Senior Lead Full Stack Software Engineer Application Development in United States

ROLE SUMMARY: The key strategic focus within the Internal Medicine Research Unit (IMRU) is identifying novel therapies to prevent or treat metabolic diseases such as obesity and cardiovascular disease. Our goal is to build a world-class research team of dedicated scientists committed to developing a deep mechanistic understanding of the metabolic pathways underlying disease pathogenesis. As a senior scientific leader and member of the obesity discovery biology team, this individual will play a significant role in shaping the scientific direction for the obesity therapeutic area and influencing broader IMRU research strategy and portfolio priorities. The individual will help create and drive discovery research strategy across multiple programs, including target ideation, validation, translational biomarker strategy, hypothesis testing, and early clinical development within the IMRU obesity portfolio. The successful candidate will lead through both direct team leadership and influence across multidisciplinary partners, helping align scientific decisions across discovery biology, translational sciences, clinical, computational, and external collaborators. The individual will identify emerging therapeutic opportunities, advance portfolio programs with scientific rigor and urgency, and represent research strategies to internal leadership and the external scientific community. Knowledge and experience in the study of metabolic pathways are essential, and familiarity with the pathophysiology of dysmetabolic states would be advantageous. Strong self-motivation, excellent communication and interpersonal skills, and the ability to lead, mentor, and build scientific capability in a highly collaborative environment are essential. ROLE RESPONSIBILITIES: Shape and influence the scientific direction for discovery research programs aligned with IMRU therapeutic area and portfolio strategy. Ap

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Staff Network Engineer Location: MPK/Bellevue/Dublin Snowflake's Enterprise Technology Network Services team is looking for a Senior Network Engineer to lead the design, operation, and optimization of our Zero Trust and secure-access platform. This role is Zscaler-centric — you will own the health, performance, and roadmap of our ZIA/ZPA deployment — while working across a modern, multi-cloud network stack that supports a global workforce of 10,000+ users. You'll be the escalation point for the most complex connectivity issues and a driver of automation and observability across the environment. What You'll Do Own and operate the Zscaler platform (ZIA, ZPA, ZDX, ZCC) end-to-end, including policy frameworks, app-segmentation models, PAC/traffic-forwarding standards, App Connector topology, and NSS/log-streaming design. Troubleshoot secure-access incidents like tunnel flapping, broker/connector health, SSL inspection edge cases, DNS/DTLS failures, and lead root-cause analysis for systemic issues. Manage Palo Alto firewalls, Panorama and GlobalProtect VPN, while planning migration toward Zscaler solutions. Support Aruba (Central) Wireless, Ekahau and Cisco Catalyst switches globally. Design, install, and configure network devices and ISP circuits at new offices. Build automatio

Developers don’t want more marketing. They want relevance, technical depth, and experiences worth showing up for. As Field Marketing Manager you will help bring Coder’s regional marketing programs to life. You will execute field and ABM programs that build awareness, support sales, and create pipeline across the North American market. You will work closely with a Senior Marketing Manager, sales, partners, and the broader marketing team. You will coordinate events, activate campaigns, and keep programs moving on time and on brand. What you’ll do here Execute regional field marketing plans aligned to global strategy and North America priorities. Run virtual and in-person events that people actually remember, from platform engineering roundtables to developer meetups to enterprise field programs. Support lead generation and pipeline goals through strategic programs, clear handoffs, and timely follow-through. Partner with global marketing teams to localize campaign content and messaging for North American audiences. Help execute co-branded campaigns and joint event opportunities with strategic alliances, resellers, and channel partners. Partner closely with sales on ABM plays for high-priority accounts, helping turn target account lists into real conversations and pipeline. Coordinate account-specific assets, communications, and campaign touchpoints that support sales outreach and pipeline creation. Support pre-event ABM motions, including target account coordination, personalized outreach support, and follow-up planning. Keep projects organized, timelines moving, and chaos to a minimum across regional campaigns and events. What we’re looking for 4–7 years of field marketing experience, preferably in B2B technology or developer-focused companies. Hands-on experience executing regional field marketing programs, including events, partner campaigns, and sales-aligned marketing motions. Experience supporting or executing account-based marketing programs, including target ac

Replit is the agentic software creation platform that enables anyone to build applications using natural language. With millions of users worldwide, Replit is democratizing software development by removing traditional barriers to application creation. Replit is changing who gets to build software. As an agentic software creation platform, Replit enables anyone, from individual creators to teams inside the world’s largest companies, to turn natural language into applications, internal tools, dashboards, workflows, websites, and software that solves real problems. We are looking for a Director or VP of Communications to help lead Replit’s next chapter of storytelling, reputation building, and market awareness. This is a senior communications role for a creative, strategic, and hands-on leader who can help build and scale the communications function as Replit grows from a beloved developer platform into a defining company in AI, software creation, and enterprise transformation. This person will help own Replit’s external and internal communications strategy, including company narrative, media relations, analyst relations, executive communications, internal communications, crisis communications, customer storytelling, policy-related communications, and global awareness. The role requires someone who can push through the noise and make the Replit story heard and for it to be a part of the narrative at all times. The Director / VP of Communications will help develop a compelling narrative that evolves with the company, the product, and the market, and deliver that narrative to the audiences across media, policymakers, partners, customers, potential ones and employees.The role will also support Replit’s international awareness, with a focus on key markets in Europe and Asia. This person must be both strategic and execution-oriented. They should have been able to build a comms function at a fast-growing technology company or have been the second in command at one. But, this

We’re looking for an experienced sourcing leader to join the Datadog Procurement team and help grow the Strategic Sourcing group. Make an impact by partnering closely with senior technology and business leaders, owning our fastest-growing AI, neocloud, and inference spend end-to-end, and continuing to prove the value that Strategic Sourcing brings to the organization. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Own the AI spend category end-to-end, covering foundation-model and AI APIs, AI development and productivity tools, and AI-enabled SaaS (with neocloud and inference compute as an emerging area), while developing and executing category strategies aligned to business objectives Champion AI and automation adoption across the sourcing function by identifying tools (e.g. Claude, ChatGPT) and building repeatable workflows that make sourcing faster, smarter, and more scalable Lead high-value AI vendor negotiations spanning foundation-model and API agreements, AI development and productivity tools, and AI SaaS, structuring seat- and consumption-based pricing across net-new purchases and strategic renewals, and building neocloud and GPU-capacity capability as the category grows Partner with Engineering and Finance to turn architectural and consumption trade-offs into commercial business cases, forecasts, and savings targets Build pricing and consumption models and apply FinOps discipline to quantify buying scenarios and uncover savings across a fast-moving spend base Work alongside executive and senior technology leadership as a trusted advisor on AI and neocloud investment decisions, influencing strategy and commercial trade-offs at the leadership level Track category KPIs (savings, pipeline, cycle time), monitor AI market, vendor, and pricing trends,

MongoDB’s Security Product Management team is seeking a Staff Product Manager to own security, compliance, and public sector product strategy within Atlas for Government (A4G). In this role, you will be a key member of the security product management team, helping make data security a market differentiator that enables MongoDB to win in enterprise and regulated industries. You will lead product strategy and execution for capabilities and programs that support federal compliance requirements and broader regulated-industry needs. You will work across Engineering, Compliance, Legal, Security, and Go-to-Market teams to translate complex regulatory and customer requirements into clear product investments, roadmaps, and outcomes. This role is suited for a candidate who can orchestrate multiple interlinked product areas, own cross-team product and architectural trade-offs, and align senior stakeholders around multi-year bets. You will be expected to identify opportunities and dependencies that cut across team boundaries, bring clarity to ambiguous problem spaces, and establish reusable ways of working that help MongoDB deliver secure, compliant platform capabilities for public sector and other regulated markets. You will partner closely with senior engineering and business leaders to evaluate trade-offs, sequence investments, and bring clarity to decisions that balance customer impact, execution risk, and long-term business value. This role can be based out of of our offices or remotely in the United States. The Federal Risk and Authorization Management Program (FedRAMP) is a US government-wide program that provides a standardized approach to security assessment, authorization, and continuous monitoring for cloud products and services. Our FedRAMP program requires that anyone who is accessing customer data or metadata inside the Authorization Boundary be a US Person on US Soil. Responsibilities Security and Compliance Product Strategy Own the public sector compliance roadm

About the Team OpenAI’s Legal team plays a crucial role in advancing our mission by tackling novel and consequential legal issues in AI. The commercial infrastructure legal team supports the systems and facilities that make advanced AI possible, including compute, first-party silicon, colocation, and first-party data center development. About the Role We’re seeking a senior commercial infrastructure lawyer to lead legal work across our rapidly growing data center development and colocation portfolio. You will advise on complex, high-value transactions involving new data center sites, power, construction, colocation, and related infrastructure arrangements. This role is designed for a lawyer who understands how data centers are developed and operated—not a general real estate practitioner. You will work closely with infrastructure, finance, procurement, and operations teams, while coordinating outside counsel where appropriate, to help projects move quickly and responsibly. San Francisco is preferred, and occasional travel may be required. In this role, you will: Lead commercial legal strategy and risk management for data center development and colocation transactions. Draft, negotiate, and advise on colocation agreements, construction agreements, power-related arrangements, and other contracts supporting data center development. Support first-party projects involving raw land, site and power rights, design and construction, EPC models, third-party build-to-suit structures, and leasebacks. Partner cross-functionally with infrastructure, finance, procurement, operations, and other stakeholders on fast-moving, complex projects. Manage and collaborate effectively with outside counsel across a high volume of infrastructure matters. Develop scalable legal playbooks and contracting approaches for a growing portfolio of data center sites. You might thrive in this role if you have: 12+ years of legal experience, primarily in commercial legal roles. Deep, hands-on experience

About the Team OpenAI’s mission is to ensure that general-purpose artificial intelligence benefits all of humanity. Our Communications team includes External Communications, Internal Communications, and other strategic communications functions. This team’s ethos is to support OpenAI's mission and goals by clearly and authentically explaining our technology, values, and approach to safely building powerful AI. About the Role We’re looking for a senior communications leader to shape how OpenAI communicates about its emerging ads and monetization business. This person will define the global narrative, lead communications for major product and business milestones, and build sustained programs that explain our approach to ads and monetization clearly and credibly. The role will be central to showing how OpenAI can develop advertising experiences that are useful to people, valuable to businesses, transparent in how they work and consistent with our mission. You will work closely with Product, Go-to-Market, Marketing, Policy, Legal and Partnerships to anticipate opportunities and risks, develop integrated campaigns and help the business scale with trust. You will also serve as a trusted advisor to senior leaders on positioning, reputation, media strategy and the broader industry conversation. This is both a strategic and hands-on role. The right person will be comfortable defining a long-term communications strategy, building the systems and relationships needed to execute it, and personally leading through high-profile launches and fast-moving issues. This role reports to the VP of Communications and is based in San Francisco, CA. We use a hybrid work model of four days per week in the office and offer relocation assistance In this role, you will: Define and lead communications strategy for OpenAI’s ads and monetization initiatives, from global narrative development through launches and sustained storytelling. Build a clear, differentiated story about how OpenAI approache

About the Team OpenAI's research training infrastructure powers how our frontier models are trained and evaluated. The Simulation team sits at the intersection between the agentic harness that powers OpenAI's products and the research infrastructure where GPT-next is trained, ensuring that our model's training environment is as realistic as possible. This team owns the integration layer that connects our production harness capabilities into the training stack. The work is highly cross-functional and high leverage: researchers depend on it to run experiments and evaluations reliably as well as to develop the next generation of harness capabilities. Failures in this surface can materially affect training velocity and correctness. About the Role We're looking for a Principal Software Engineer to lead the architecture and evolution of the Simulation Platform. You'll own a critical interface between research and engineering, building the systems, APIs, and operational patterns that let researchers use agentic coding infrastructure safely and effectively in training environments. This role is ideal for a senior backend or infrastructure engineer with strong technical judgment, product sense for highly technical users, and the ability to drive execution across multiple teams. The highest-leverage work is building robust infrastructure that supports and accelerates research without compromising engineering quality. In this role, you will Design, build, and evolve the integration between the Codex harness that powers OpenAI's products and research training infrastructure used for training GPT-next Build a platform for our LLMs to train and be evaluated in simulated environments that mimic their deployment setting as closely as possible, on every axis: agentic harness, compute substrate, timing, tools, data sources, humans in the loop, and more Own major integration surfaces end-to-end, from architecture and API design through rollout, operations, and long-term maintenance Bu

About the Team OpenAI’s User Operations team shepherds our customer’s adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. About the Role We are looking for a Technical Program Manager to join our Senior Support Engineering team. This role is an exciting opportunity to help define and implement foundational support practices that will scale with OpenAI’s growth. You will lead efforts to establish new operational frameworks, driving process alignment with various internal teams, and leading tooling and automation projects. This position offers the chance to make a significant impact in shaping customer experience while collaborating across multiple teams. We’re looking for people who thrive at the intersection of project management, systems building, data science/data engineering/software engineering, team enablement, and customer advocacy – and enjoy working cross-functionally in a fast-paced, evolving environment. This role is based in San Francisco, CA, and follows a hybrid work model of 3 days in-office per week. Relocation assistance is available. In this role, you will: Lead support delivery programs for Tier 3 frontline delivery for our most strategic customers, including productivity and workflow improvements, team operations, and knowledge management for the Support Delivery team Partner with Support Delivery and cross-functional leadership to define the experience, stand up the program, manage pilots and rollout, and ensure premium operations and

About the Team Our Robotics team is focused on unlocking general-purpose robotics and pushing towards AGI-level intelligence in dynamic, real-world settings. Working across the entire model stack, we integrate cutting-edge hardware and software to explore a broad range of robotic form factors. We strive to seamlessly blend high-level AI capabilities with the constraints of physical systems to improve peoples’ lives. About the Role We are seeking a Senior Mechanical Engineer to lead the design, integration, and sustaining engineering of mechanical subsystems in robotic platforms. You will work closely with experienced engineers and cross-functional partners to set functional requirements, develop and iterate on hardware to meet program expectations. This role is aimed at candidates with strong fundamentals in mechanical system design — including tolerance, alignment, load paths, wear, and failure modes — and robotics. You will contribute to real hardware programs moving from prototype through early production. You will lead both new subsystem development and ongoing improvements to existing systems based on testing, field performance, and manufacturing feedback. This role is based in San Francisco, CA, and requires in-person presence 4 days a week. In this role, you will Lead the design and iteration of mechanical subsystems, including structures, mechanisms, and actuators. Create and maintain CAD models, assemblies, and drawings with appropriate tolerancing and documentation. Build and test prototypes, supporting debugging of mechanical issues such as fit, alignment, friction, and wear. Assist in developing test methods and executing validation to evaluate performance, durability, and failure modes. Work with cross-functional teams to integrate mechanical components with sensors, actuators, and control systems. Support transition of designs from prototype to manufacturable assemblies, incorporating DFM and DFA considerations. Collaborate with manufacturing partners

About the Team: OpenAI, in close collaboration with our capital partners, is embarking on a journey to build the world’s most advanced AI infrastructure ecosystem. Our Stargate program develops and deploys massive, state-of-the-art data center campuses in partnership with industry leaders today—and through future OpenAI infrastructure projects tomorrow. We design for scale, speed, and reliability, and we need experienced technicians who can translate network blueprints into physical reality. About the Role: We are seeking a Senior Data Center Networking Technician who thrives in fast-moving build environments and is eager to roll up their sleeves during active datacenter deployments. Your first assignment will focus on the physical bring-up of network infrastructure at a large partner-operated campus, collaborating with partner teams and their delivery vendors to achieve agreed performance and reliability targets. As that campus reaches steady state, you will transition to lead network deployment for future OpenAI data center projects, defining standards and guiding implementation across multiple locations. Candidates must be able to sit onsite in Abilene, Texas 5 days per week Key Responsibilities Serve as OpenAI’s technical lead technician during the current campus build, partnering with internal engineers and external contractors on design reviews, installation plans, and acceptance criteria. Spend significant time on the data-center floor performing inspections, assisting with cable routing/termination when needed, conducting fiber testing (OTDR, power levels, continuity), and resolving installation challenges in real time. Troubleshoot and optimize cabling routes, patching, and equipment turn-up to ensure clean, reliable handoff to network operations. Contribute to design discussions and peer reviews for structured cabling and physical network layouts, providing practical field feedback to engineering teams. Develop repeatable engineering standards, as-built do

About the team OpenAI’s mission is to build safe artificial general intelligence (AGI) which benefits all of humanity. This long-term undertaking brings the world’s best scientists, engineers, and business professionals into one lab together to accomplish this. In pursuit of this mission, our Go To Market (GTM) team is responsible for helping customers learn how to leverage and deploy our highly capable AI products across their business. The team is made of Sales, Solutions, Support, Marketing, and Partnership professionals that work together to create valuable solutions that will help bring AI to as many users as possible. About the Role OpenAI is building a dedicated Digital Natives vertical focused on high-growth technology and internet companies shaping the future of software. As a Sales Manager, you will recruit, develop, and lead a team of senior Account Directors responsible for landing and expanding OpenAI’s largest and most strategic Digital Native customers. You will define how we win in this segment — establishing the operating cadence, deal strategy, and vertical GTM playbook for engaging sophisticated, technically fluent buyers building AI into their core products. You will operate as a hands-on front-line leader: deeply involved in complex opportunities, elevating sales discipline, and shaping how OpenAI scales enterprise revenue in the most dynamic segment of the market. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. Key Responsibilities Recruit and develop a high-performing team of Account Directors. Establish a coaching culture centered on rigorous deal reviews, structured 1:1s, and clear performance standards. Raise the talent bar continuously through thoughtful hiring, development, and accountability. Architect and refine the GTM strategy for high-growth tech and internet companies. Shape territory design, account prioritization, and coverage mo

About the team OpenAI’s mission is to build safe artificial general intelligence (AGI) that benefits all of humanity. Achieving this requires bringing together world-class scientists, engineers, and business leaders to translate frontier research into real-world impact. Within OpenAI, the Go-to-Market organization helps customers understand, adopt, and scale our products across their businesses. The team includes Sales, Solutions, Support, Marketing, Partnerships, and Strategic Pursuits professionals who work together to bring the benefits of AI to organizations globally. About the role We are hiring a Senior Specialist Seller to join the Strategic Pursuits team and lead priority opportunities generated through the joint AWS and OpenAI co-sell motion. You will partner closely with Account Directors, AWS field teams, and cross-functional stakeholders to identify, shape, advance, and close high-value strategic enterprise engagements. This role is ideal for a senior seller with deep experience in enterprise technology, AI, cloud, or complex transformation sales motions. You should be comfortable operating in executive-facing environments, aligning multiple stakeholders, and turning customer priorities into commercially compelling and technically credible opportunities. This role is based in San Francisco, Seattle, or New York. We operate on a hybrid model of 3 days per week in office and offer relocation support. We are also open to remote candidates based in the United States. In this role, you will: Lead commercial execution of priority AWS/OpenAI co-sell opportunities across strategic enterprise accounts. Identify and qualify high-potential opportunities focused on GenAI adoption, frontier platform use cases, and enterprise-wide transformation. Partner with AWS and OpenAI field teams to align account strategy, messaging, stakeholder mapping, and execution plans. Develop customer-facing value propositions that connect OpenAI capabilities with business priorities and

About the Team OpenAI’s Hardware organization develops system and infrastructure solutions designed for the unique demands of advanced AI workloads. We work closely with architecture, infrastructure, and vendor teams to evaluate system performance and guide critical design decisions. Our team focuses on building and applying performance modeling frameworks to understand system behavior, quantify tradeoffs, and support next-generation infrastructure design. About the Role We are seeking an Performance Modeling Engineer to support the development and application of modeling tools used to evaluate AI system performance and inform architectural decisions. In this role, you will partner closely with Senior Performance Modeling Engineers and the Performance Modeling Lead to analyze system behavior, run simulations and analytical models, and help evaluate tradeoffs across compute, memory, networking, and storage. You will contribute to building modeling frameworks while developing a strong foundation in system architecture and AI infrastructure. This role is ideal for early-career engineers with 1–2 years of experience in software engineering, systems analysis, or performance modeling who are excited to grow in large-scale infrastructure and hardware/software systems. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance. Key Responsibilities Support the development and maintenance of performance modeling tools and frameworks Assist in building models to evaluate system behavior across compute, memory, networking, and interconnect subsystems Help analyze distributed system scaling behavior and identify performance bottlenecks Run simulations and analytical models to support architecture and infrastructure decisions Partner with senior engineers to evaluate design tradeoffs across hardware and system components Interpret modeling outputs and help translate findings into clear recommendations Vali