Jobs in United States

Senior Lead in United States

2,005 active opportunities · Updated October 2026

Explore current senior lead jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

G
📍 California, United States
✓ High-confidence listingCompany trend +165.2%

$281K – $363.7K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description At Gilead our pursuit of a healthier world for all people has yielded a cure for hepatitis C, revolutionary improvements in HIV treatment and prevention as well as advancements in therapies for viral and inflammatory diseases and certain cancers. We set and achieve bold ambitions in our fight against the world's most devastating diseases, united in our commitment to confronting the largest public health challenges of our day and improving the lives of patients for generations to come. As a Executive Director, HIV Treatment Integrated Insights , at Gilead you will serve as the senior strategic insights leader supporting the HIV Treatment Business Unit. Reporting to

Artificial IntelligenceAIFinanceRecruitment
A
📍 San Francisco, United States· Full-time
✓ High-confidence listingCompany trend -98.8%

From $232K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: Our Product Managers imagine the ideal experience for our community and work backwards, creating innovative products that delight our guests and hosts. They deeply understand the needs of our users and translate these into a strategy that combines strong product thinking and deep research. They partner with talented cross-functional team members across engineering, design, operations, data science, and more, leading teams to execute a shared vision. They are incredibly detail-oriented and hands on. The Difference You Will Make: Airbnb is seeking an exceptional product manager to reimagine how guests search on Airbnb. Search is the front door to the entire guest experience — the moment someone tells us what they want and we have to understand it, then show them the right options in the right order. Today that means query understanding, filtering, and ranking. Tomorrow it means next-generation AI capabilities that let guests search more naturally, get better matches with less effort, and trust that Airbnb understood what they were actually looking for. In this role, you will own the vision and roadmap for the future of search at Airbnb — pushing beyond keyword and filter-based search toward more intelligent, conversational, and personalized ways for guests to find their perfect stay. You'll partner closely with engineering, design, and data science teams to bring new AI-powered search capabilities from concept to guests. This is a high-visibility role building one of the most consequential surfaces in the guest experience, and will regularly interface with senior engineering and leade

C
📍 United States· Remote
✓ High-confidence listingCompany trend +340.2%
Quick readStrong listing-quality and freshness signals

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Position Summary The Manager, Care Model is responsible for owning the day‑to‑day execution of a defined care model workstream, ensuring planned activities are delivered on time and with high quality. This role translates care model strategy and direction into detailed task‑level plans, coordinates functional contributors, and drives daily follow‑through on actions, milestones, and deliverables. The Manager focuses on tactical execution, detailed tracking, and issue management, proactively identifying risks and escalating impacts that may affect the broader care model timeline. This role serves as a key operational partner to the Workstream PM and Senior Care Model leadership by providing accurate status, maintaining workstream artifacts, and ensuring reliable inputs into integrated reporting. Own day‑to‑day execution of a defined care model workstream, delivering tasks and milestones as planned Develop and maintain task‑level work plans; track actions, owners, dependencies, and due dates Coordinate functional contributors to support timely completion of workstream deliverables Identify and manage workstream‑level risks and issues; propose mitigation options and timing impacts Escalate risks, issues, or slippage impacting the broader care model critical path Provide accurate, timely status updates and inputs to integrated workstream reporti

O
📍 San Francisco, California, United States
✓ High-confidence listingCompany trend 0%
Quick readStrong listing-quality and freshness signals

Secure Every Identity, from AI to Human Identity is the key to unlocking the potential of AI. Okta secures AI by building the trusted, neutral infrastructure that enables organizations to safely embrace this new era. This work requires a relentless drive to solve complex challenges with real-world stakes. We are looking for builders and owners who operate with speed and urgency and execute with excellence. This is an opportunity to do career-defining work. We're all in on this mission. If you are too, let's talk. The Global Pricing Operations Team The Pricing Operations team works in a cross-functional, fast-paced, and dynamic environment with many moving pieces and evolving business needs. The team partners with Pricing Strategy Managers, Product Managers, Technology, Data & Intelligence, and various GTM teams to ensure Okta is operationally ready to bring new product pricing, buying programs, and strategic monetization initiatives to market. The Pricing Operations Principal Opportunity Okta is seeking a Pricing Operations Principal to lead initiatives that transform Okta's pricing strategy into successful go-to-market execution. A successful person in this role will be a strong collaborator, intensely curious, and supremely organized. They are known for connecting the dots, simplifying complexities, communicating clearly and proactively, and driving highly collaborative efforts to completion, even when the path forward isn't perfectly defined. In this role, you will serve as an operational leader for new pricing launches and a strategic buying-program implementation, establishing the integrated roadmap, operating cadence, decision-making framework, readiness criteria, and stakeholder communications required to bring these initiatives from concept through launch and sustained adoption. You will partner closely with senior cross-functional leaders to make complex tradeoffs, resolve dependencies, and ensure the business is ready to sell, quote,

Machine LearningArtificial IntelligenceAISalesforce
O
📍 Washington, District of Columbia, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team OpenAI's mission is to ensure that artificial intelligence benefits all of humanity. OpenAI for Government works with U.S. and allied government institutions to support the responsible adoption of AI across defense, intelligence, federal civilian, state and local, and international public-sector missions. We work at the intersection of technology, policy, operations, security, and delivery to help public servants use frontier AI in ways that are effective, trusted, aligned with democratic values, and grounded in real-world consequences. The team helps government agencies transform how they work through secure, compliant AI tools and mission-aligned deployments, including ChatGPT Enterprise, ChatGPT Gov, APIs, Codex, and emerging frontier capabilities. We partner with government leaders, operators, technologists, and policy stakeholders to translate cutting-edge AI into measurable mission impact while meeting government requirements for safety, reliability, security, compliance, and trust. Cyber is a critical government mission area. OpenAI's government cyber work brings together OpenAI for Government, Product, Research, Security, Product Policy, Legal, Global Affairs, and Communications to help trusted public-sector defenders responsibly use AI to protect government networks, critical infrastructure, and national-security systems. About the Role We are seeking a senior government cyber leader to serve as Head of Government Cyber Integration for OpenAI for Government. This role will integrate OpenAI's government cyber work across strategy, testing and evaluation, trusted access, deployment, policy, security, and external engagement. This is a matrix leadership role, not a replacement for line management. Product teams still own product roadmaps. Research and Safety still own model capability measurement and risk mitigation. Security still owns OpenAI's security posture and customer security requirements. Product Policy, Legal, and Global Affairs still

AWSRestAIGo
N
📍 Santa Clara, United States
✓ High-confidence listingCompany trend -8%
Quick readStrong listing-quality and freshness signals

As one of the technology industry's most desirable employers, NVIDIA has been redefining accelerated computing, computer graphics and leading the Artificial Intelligence revolution. NVIDIA's innovation is fueled by its great technology—and amazing people. We are seeking a Senior Silicon and System Product Lead to influence, innovate and take our next generation products to the market. As part of the Silicon Solutions Team, we architect and deliver groundbreaking system solutions that integrate all aspects of the system from silicon design, software design to operations and final deployment in multiple market segments that NVIDIA serves. This position offers an unique opportunity to collaborate with multiple organizations in the company and grow your career in a high impact role. We need a passionate, hard-working and creative individual to lead the products all the way from market analysis to delivering the features on the final product. What you'll be doing: Drive product performance and power targets, trade-off features/configurations and provide innovative solutions to complex silicon and system level problems. Evaluate new market segments and use cases; translate market requirements to engineering problem statements and metrics. Innovate Performance, power, yield and quality optimizations and features for the world’s fastest power-shipping products in the GPU and SoC market segments spanning gaming, automotive, datacenter and DL/AI. Develop methodologies and requirements for multi-functional teams to drive silicon and system product features to production. Incorporate productization feedback to improve the next generation. Lead the team for feature requirements and schedule from architecture to silicon phase of projects. Work alongside system architects, designers, marketing teams, chip and board designers, software/firmware engineers, HW/S

Artificial IntelligenceAI
N
📍 Santa Clara, United States
✓ High-confidence listingCompany trend -8%
Quick readStrong listing-quality and freshness signals

NVIDIA has been transforming computer graphics, PC gaming, and accelerated computing for more than 25 years. It’s a unique legacy of innovation that’s fueled by great technology—and amazing people. Today, we’re tapping into the unlimited potential of AI to define the next era of computing. An era in which our GPU acts as the brain of computers, robots, and self-driving cars that can understand the world. Doing what’s never been done before takes vision, innovation, and the world’s best talent. As a NVIDIAN, you’ll be immersed in a diverse, supportive environment where everyone is inspired to do their best work. Come join the team and see how you can make a lasting impact on the world. NVIDIA Silicon Codesign Group is seeking a versatile engineer to join the HW bring-up methodology team. The SCG team is uniquely positioned to have an end-to-end view of the product development cycle - from early architecture definition, through bringup, to product release. What will you be doing: Led end-to-end planning and on-time execution of Nvidia's new chip bringup effort, from pre-silicon through production deployment. Coordinate multi-functional teams across Architecture, Build, Validation, DFT, SW, System, and Operations to drive shared bringup achievements. Improve cross-team communication, work, and handoffs. Develop and standardize methodologies, processes, and workflows for silicon bringup, creating reusable checklists and playbooks. Drive scheduling, equipment, and material logistics to support ambitious NPI and production schedules. Lead post-action reviews and convert learnings into concrete process improvements for future silicon and solution bringups. Contribute to post-silicon learnings that feed back into architecture, design, and pre-silicon

AILogistics
P
📍 Connecticut, United States
✓ High-confidence listingCompany trend +671.4%

$88.5K – $147.5K/yr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY The Asset Lifecycle Management (ALM) Lead is responsible for the systematic tracking, installation, and removal of laboratory equipment throughout the entire lifecycle, from acquisition through deployment, maintenance, and final disposal. Operating within an R&D environment, this role facilitates asset preplanning, site assessments, and ensures all asset-related activities are documented, tracked, and compliant with regulatory standards. By optimizing equipment usage, managing inventory, coordinating maintenance, and driving process improvements, the ALM supports efficient and safe laboratory operations while controlling costs and enabling the lab for evolving technological requirements. This is to include but not be limited to supporting the regular updates and reconciliation of the Fixed Asset Registry (FAR) and physical inventory field activities. With input from both the customer equipment owner and the original equipment manufacturer (OEM), this role will develop the correct service program for assets within EAMS (Enterprise Asset Management System) or Pfizer’s Computerized Maintenance Management System (CMMS). Additionally, this position will be responsible for the documentation of asset maintenance activities within EAMS and support site EAMS administration requiring the review of training requirements and On the Job Training (OJT) for new resources requiring system access. The Asset Lifecycle Manager will also represent the site on various Global Workplace Experience (GWE) Communities of Practice or multi-site or global teams ensuring best practices and standards are being leveraged across the broader R&D portfolio. This position will foster and maintain working relationships with GWE, Preclinical & Translational Sciences (P&TS) Research and business operations team colleague and contractors to analyze needs, provide recommendations, and execute plans and options that ali

AIExcelProject ManagementAccounting
C
📍 Tampa Florida United States, United States
✓ High-confidence listingCompany trend +800%
Quick readStrong listing-quality and freshness signals

This is a senior attorney role to lead the negotiation and execution of derivatives documentation supporting our global Markets trading activities. This role will serve as a key partner to front office, risk, and legal teams, managing complex master trading agreements, such as ISDA and Futures Clearing agreements, and advising on legal and regulatory risk across OTC derivatives transactions. The position requires deep expertise in ISDA Master Agreements, collateral documentation, and derivatives market practice, along with strong stakeholder management and negotiation capabilities. Responsibilities: Serve as lead negotiator and subject matter expert for ISDA Master Agreements, Schedules, Credit Support Annexes (CSAs), and related derivatives and collateral documentation; manage complex, bespoke negotiations across the full documentation lifecycle Provide legal counsel and guidance to Markets business stakeholders, interpreting applicable laws, rules, regulations, and industry practices and delivering commercially practical, risk-appropriate solutions Advise senior management on legal matters impacting trading activities, client relationships, and strategic initiatives, contributing informed, business-oriented perspectives to decision-making Identify, evaluate, and manage legal, regulatory, and reputational risk in coordination with Legal, Risk, and ICRM; ensure alignment with internal policies and applicable regulatory requirements Objectively assess business proposals against institutional risk appetite, regulatory frameworks, and market standards, escalating issues as appropriate Collaborate closely with Trading, Sales, Credit, Risk, Operations, and Legal teams across regions to deliver coordinated, efficient, and consistent outcomes Oversee day-to-day legal and documentation activities as a subject matter expert, ensuring tim

Artificial IntelligenceAI
C
📍 Farmington, United States
✓ High-confidence listingCompany trend +340.2%
Quick readStrong listing-quality and freshness signals

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Position Summary At Aetna®, part of CVS Health, we proudly serve more than 26 million medical members through our broad range of health plan offerings. We're committed to delivering a simpler, more meaningful, and personal health care experience to each of them. As a Senior Manager Medicare Product, Vendor Management Contract Lead you will play a critical role contracting, negotiations, oversight of vendors and assisting in achieving CVS goals, work strategically together, and remain as adaptable as possible in an ever-changing environment. This role's scope of responsibility includes overseeing the following in relation to Medicare Product vendor management: Finance, Contracts, Invoicing, Negotiations, Provisioning, Aetna Medicare Supplemental & Duals benefits, Vendor relationship management, Compliance oversight, Auditing, and projects as assigned. The Senior Manager, Vendor Management Contract Lead is a high impact role. You will lead advance contract and negotiation skills, work with other partner to identify root cause, address, and resolve vendor issues, manage vendors to the contract SLAs, performance guarantees and provide insight into complex vendor problems. Responsibilities include: Work assignments involving moderately complex to complex issues where the analysis of situations or data requires an in-dep

FinanceAuditing
G
📍 California, United States
✓ High-confidence listingCompany trend +165.2%

$157.6K – $203.9K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description Gilead Sciences is seeking a collaborative, hands-on leader to shape and deliver the ERP capabilities for a new, next-generation bulk drug substance manufacturing facility at our Foster City site. As the site’s SAP business lead, you will translate operational needs into integrated processes across production, procurement, quality, and warehousing. Working closely with site stakeholders and the IT implementation team, you will define requirements, guide implementation, and connect SAP with other digital platforms to help create a compliant, paperless manufacturing environment. R

SapLogisticsProcurementWarehouse
G
📍 California, United States
✓ Quality checkedCompany trend +165.2%

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Real-World Evidence (RWE) function at Gilead is part of the Clinical Data Sciences (CDS) group within the Clinical Development organization and aims to unlock the power of Real-World Data (RWD) to help transform innovations to life-changing medicines for patients. We are seeking a Senior Director, RWE Inflammation Product Lead who will be accountable for the development and execution of the RWE strategy in support of one or more Inflammation products under development. The incumbent will serve as the key RWE subject matter expert within Gilead's lifecycle management teams for the product(s) and all its indications across the development lifecycle and serve as a strategic

Recruitment
N
📍 Santa Clara, United States
✓ High-confidence listingCompany trend -8%
Quick readStrong listing-quality and freshness signals

We at NVIDIA seek an Senior Developer Relations, Automated Synthetic Chemistry Science Lead who can coordinate science streams. This role exists at the crossroads of experimental science, optimization, analytical characterization, AI modeling, laboratory automation, and data infrastructure. It demands a practitioner with a background in research who can lead interdisciplinary science teams and accelerate experimentation without compromising scientific quality. What you'll be doing: Coordinate the operating plan across research priorities, technical execution, and program achievements. Convert research objectives into experimental priorities, parameter-space development, campaign planning, and success criteria. Lead research initiatives encompassing synthetic chemistry, catalysis, process chemistry, machine learning, automated systems, and data processing. Build standardized experimental traces capturing successful and unsuccessful outcomes, metadata, quality-control signals, analytical summaries. Guide AI systems for feasibility assessment, outcome prediction, optimization, scope exploration, and campaign orchestration. Integrate automated experimentation, analytical data streams, data curation, model retraining, and campaign decisions into a closed-loop operating model. Establish science-stream governance: build reviews, decision logs, risk and dependency tracking, quality thresholds, and paths for addressing blocking issues. Prepare recurring workstream readouts for program leadership, including scientific progress, critical decisions, cross-team dependencies, resource needs, and unresolved risks. What we need to see: PhD (or equivalent experience) with 10+ years of hands-on experience in experimental science, chemical engineering, material science, robotics, a

Machine LearningAI
I
📍 Minnesota, United States· Full-time· Remote
✓ High-confidence listingCompany trend -100%

From $265K/yr

Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Overview Enterprise Foundations is the engineering team responsible for the architectural and integration work that allows Instacart's Retailer Platform to scale across the world's largest grocers. Our work spans omnichannel integrations — bringing products like FoodStorm catering and Caper Carts onto unified Instacart platform rails — enterprise extensibility (sandbox environments, configuration systems, retailer-facing tooling), and the cross-cutting data isolation work that allows Instacart's ML and Data Engineering teams to safely build per-retailer models on top of the platform. As Instacart's enterprise retail business expands to hundreds of partner brands and new international markets, this team's work is foundational to how the platform matures. We are seeking a Senior Engineering Manager to lead this team of ~12 engineers. You'll set the unifying technical

AWSGCPAIGo
P
📍 New York, United States
✓ High-confidence listingCompany trend +671.4%

$139.1K – $231.9K/yr

Quick readStrong listing-quality and freshness signals

As a leading biopharmaceutical company, Pfizer is dedicated to the discovery and delivery of high value therapies across a variety of disease areas. It is our mission to bring innovative medicines to patients that significantly improve their lives, and our priority is to ensure patients have access to these medicines. The Health Technology Assessment (HTA), Value & Evidence (HV&E) team is responsible for ensuring patients have affordable, timely access to medicines and vaccines by advancing innovative value and evidence solutions to inform healthcare decision-making. ROLE SUMMARY The HTA, Value & Evidence Senior Manager is responsible for development and execution of high-quality HV&E strategic efforts to support optimal access and reimbursement for treatments in Oncology. This role directly impacts the ability to achieve business objectives on a global basis by providing strategic guidance and robust evidence development relevant to achieve optimal global patient access by demonstrating the value of Oncology medicines. This position will be part of Pfizer’s dynamic HTA Value & Evidence team and will have the important role of managing health economics and outcomes research (HEOR) to generate data to support patient access to the GU Cancer Portfolio. This position will be working closely with the Oncology cross-functional teams (e.g., access, medical, clinical, commercial, etc.) and country teams to foster a culture that promotes innovation and thrives on doing better for Pfizer’s patients and society in general. This position will function in a closely aligned fashion with the Global Access Strategy and Pricing (GASP) team to ensure there is a single and coordinated view on strategy and project execution. This position will function with a ‘OnePfizer’ mindset and will work in a closely ali

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