Jobs in United States

Senior Lead Software Engineer Machine Learning in United States

2,154 active opportunities · Updated October 2026

Explore current senior lead software engineer machine learning jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

Hiring demand

51/100

steady · 558 related jobs

Hiring trend

-78.4%

Job postings compared with the previous 30 days

Remote options

15.6%

Share of matching jobs listed as remote

Typical salary

$177.2K – $177.2K/yr

Based on 29 salary observations

P
Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, United States· Full-time· Remote
✓ High-confidence listingCompany trend -86.4%

From $163.6K/yr

Quick readStrong listing-quality and freshness signals

About Pinterest: Millions of people around the world come to our platform to find creative ideas, dream about new possibilities and plan for memories that will last a lifetime. At Pinterest, we’re on a mission to bring everyone the inspiration to create a life they love, and that starts with the people behind the product. Discover a career where you ignite innovation for millions, transform passion into growth opportunities, celebrate each other’s unique experiences and embrace the flexibility to do your best work. Creating a career you love? It’s Possible. At Pinterest, AI isn't just a feature, it's a powerful partner that augments our creativity and amplifies our impact, and we’re looking for candidates who are excited to be a part of that. To get a complete picture of your experience and abilities, we’ll explore your foundational skills and how you collaborate with AI. Through our interview process, what matters most is that you can always explain your approach, showing us not just what you know, but how you think. You can read more about our AI interview philosophy and how we use AI in our recruiting process here . As a Sr. Staff Technical Program Manager for Search Signals at Pinterest, you will lead company-level programs that are foundational to Pinterest’s strategic transformation into a shopping and inspiration platform. This role is responsible for driving innovation and execution across offsite signals, content understanding, and relevance, with direct impact on multiple company OKRs. You will operate at the intersection of technical depth, cross-org influence, and long-term business strategy, shaping the future of search and personalization at Pinterest. What you’ll do: Strategic Leadership & Vision Envision and trailblaze the company’s approach to leveraging offsite and onsite signals, anticipating future business, technical, and regulatory challenges. Drive the creation and evolution of the company-wide roadmap for signals,

AWSRestAIGo
I
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -92.5%

From $240K/yr

Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Overview As a Senior Machine Learning Engineer II on the Ads Response Prediction team, you will lead the design and development of core ML models that power Instacart’s ads ecosystem. This is a research-leaning role focused on theoretical problem formulation, training methodology, and model quality rather than infrastructure or full-stack engineering. You will tackle fundamental challenges in pCTR modeling such as mitigating selection bias, position bias, and optimizer’s curse in training data, improving model calibration across surfaces and domains, and advancing our multi-task learning and sequence modeling capabilities. You will also have the opportunity to shape our next-generation foundation model approach for ads ranking and contribute to cutting-edge retrieval systems like TIGER (Transformer Index for Generative Recommenders), Semantic ID and domain language

PythonSQLMachine LearningAI
I
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -92.5%

From $183K/yr

Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Overview Instacart is seeking a Senior Manager to build, train, and lead our Technical Account Management (TAM) practice and own post-launch technical excellence for our premier Storefront Pro (SFP) product. Storefront Pro is the market leader in e-commerce solutions for grocery, combining Instacart's enormous scaling abilities with best-in-class customer experiences, while bridging online and in-store commerce. Over the past two years, SFP has grown explosively, launching triple digits of retailers ranging from local independent favorites to midsize players to multinational giants — totalling billions in revenue. You will own post-launch technical health and excellence across the entire SFP space, founding and scaling a tiered TAM organization to match the size and complexity of that portfolio. About the Job Hire, train, and develop the Technical Account Ma

ReactCI/CDGitRest
I
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -92.5%
Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Overview Instacart’s Enterprise Platform team is responsible for the white-label product that enables retailers of all sizes to compete online through their own ecommerce experiences. The team is focused on platform growth and long-term retailer success — from onboarding new partners to helping them acquire, serve, and retain their end customers in ways that align with their unique brand and strategy. We are seeking a Senior Product Manager to own two important efforts: creative tools that give retailers control over their e-commerce theme and brand experience, accelerated with AI acting as the product lead for large enterprise retailers – shaping proposals, aligning complex retailer requirements, and guiding planning cycles that unlock mutual growth This role is one of the most dynamic and high leverage roles we have. It requires someone who can move fluidly

GitAIGoRust
I
📍 Minnesota, United States· Full-time· Remote
✓ High-confidence listingCompany trend -92.5%

From $265K/yr

Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Overview Enterprise Foundations is the engineering team responsible for the architectural and integration work that allows Instacart's Retailer Platform to scale across the world's largest grocers. Our work spans omnichannel integrations — bringing products like FoodStorm catering and Caper Carts onto unified Instacart platform rails — enterprise extensibility (sandbox environments, configuration systems, retailer-facing tooling), and the cross-cutting data isolation work that allows Instacart's ML and Data Engineering teams to safely build per-retailer models on top of the platform. As Instacart's enterprise retail business expands to hundreds of partner brands and new international markets, this team's work is foundational to how the platform matures. We are seeking a Senior Engineering Manager to lead this team of ~12 engineers. You'll set the unifying technical

AWSGCPAIGo
I
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -92.5%

From $240K/yr

Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Overview The Advertiser Optimization team is the decision-making engine of Instacart's $1B+ ads business. We own the systems responsible for Bidding, Pacing, Budgeting, and Targeting: converting stated advertiser goals into real-time auction actions. Our mission is to maximize realized Advertiser Value by deciding when to participate, how much to bid, and how fast to spend, all while balancing User Experience and Platform Revenue. We are hiring a Senior Applied Scientist II to lead the algorithmic direction of these systems. This is a role for someone who thinks in terms of control theory, constrained optimization, and auction economics, and who can translate those frameworks into production code that makes millions of decisions per day. You will formulate problems from first principles, shape the technical roadmap, and own systems end-to-end from mathematic

PythonJavaAIC++
I
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -92.5%

From $185K/yr

Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Why this role is on the menu We are seeking a Senior SOX Manager to lead enterprise-wide programs focused on SOX compliance, IT controls, and controls transformation across modern technology environments. This role sits at the intersection of technical program management, digital risk, and engineering, requiring the ability to translate complex system architectures into scalable, audit-ready control frameworks. The Senior SOX Manager will own program strategy and execution, driving alignment across Engineering, Finance, Data, and Audit stakeholders to deliver automated, efficient, and sustainable control environments. What you'll cook up in your first year Program Strategy & Execution Lead end-to-end SOX programs, including planning, execution, and delivery across ITGCs, ITACs, and key business process controls Drive risk assessments, control scoping, te

AWSAzureGCPCI/CD
I
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -92.5%

From $208K/yr

Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Why this role is on the menu Instacart's Strategic Finance team partners across the business to drive disciplined growth and long-term value creation. Within this group, the Retailer pod supports our Retail Partnerships organization as we expand and deepen relationships with grocers and retailers across North America. In this role you will be the finance lead for retailer deal flow—setting financial strategy, shaping pricing philosophy, and driving portfolio-level decision-making across the full lifecycle of retailer partnerships. You will develop decision frameworks, build robust models, and advise senior leaders through high-stakes negotiations that shape Instacart’s revenue and margin profile. This is an individual contributor role to start, with a clear path to people management as the team grows. This person will report to the Director of Retailer Finan

C
📍 United States· Full-time· Remote
✓ Quality checkedCompany trend -100%

Ready to do the most impactful work of your career? At Coinbase , we are uncompromising on our mission to increase economic freedom. The bar is high, the environment is intense, and we like it that way. This isn't a place for complacency, it’s a place to be pushed past your perceived limits. If you're ready to build the future of finance alongside people who refuse to settle for "good enough," you belong here. Coinbase is a remote-first, but not remote-only company. Expect to get together quarterly for intense in-person working sessions called “surges.” learn more about working at Coinbase . As the Senior User Researcher on the Advanced Trade team within the Consumer & Business group, you'll be the dedicated research voice for Coinbase's most sophisticated traders. The Advanced Trade team builds and improves trading experiences for high-volume, analytical traders, competing directly with top global exchanges. You'll generate deep user empathy through mixed-methods research, directly shaping roadmap prioritization, feature design, and scalable research programs that keep the entire team embedded in trader needs. What you’ll do: Lead the UX research function for the Advanced Trade team, partnering closely with Design, Product, and Data to turn user insights into actionable product ideas and measurable impact. Conduct mixed-methods research, including interviews, usability testing,

A
📍 United States· Full-time
✓ Quality checkedCompany trend -98.9%

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: MarTech Data Science Measurement empowers Airbnb to optimize marketing ROI by generating data-driven recommendations. We lead the way in defining and advancing best practices for measuring and optimizing marketing impact. We collaborate with Marketing, Finance, and Engineering to provide actionable recommendations and tools based on effective, timely, and granular measurements. Our team’s tenets are: Actionable: Deliver insights that drive confident business decisions. Impactful: Prioritize projects based on their expected value to Airbnb. Balanced: Adapt methods to business questions and data realities, acknowledging limitations. Rigorous: Maintain methodological integrity and quantify the sensitivity of findings. Innovative: Invest in advancing measurement science and developing new methods. Influential: Share learnings across Airbnb and the broader data science community. The Difference You Will Make: We are seeking an experienced (Contract) Sr. Data Scientist for a 24 month contract with deep expertise in marketing measurement, with a particular focus on Marketing Mix Modeling (MMM) and geo-based causal inference. The ideal candidate brings strong statistical intuition and hands-on modeling experience to quantify the incremental impact of Airbnb's marketing investments across channels and geographies. They are fluent in Python, comfortable working with Bayesian frameworks, and can translate complex measurement findings into clear, actionable recommendations for senior stakeholders. A Typical Day: Marketing Mix Modeling: Design, build, and maintain MMM models that est

PythonSQLAIGo
A
📍 United States· Full-time
✓ High-confidence listingCompany trend -98.9%

From $179K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: We’re looking for people who know and use Airbnb and believe in what we’re trying to accomplish. Airbnb is a marketplace that connects guests and hosts, and Payments is central to creating the trust that makes every transaction possible. The Platform team plays the role of conductor, leveraging AI prototyping to bring together engineers, designers, and data scientists to build great product experiences. Our Payments Platform Managers define and execute roadmaps for their product areas, translating organizational priorities into clear plans, requirements, and measurable outcomes. The Difference You Will Make: We are building foundational platform capabilities that require expertise and experience with digital wallets and identity services, and how they interact with payment services for our guests and hosts across the world. The Senior Platform Manager, Accounts will help shape the product vision, strategy, and roadmap for the Payment Accounts area, and lead execution of cross-functional initiatives with partner teams across Payments, Trust, Guest & Host, and Compliance. This is a highly strategic role with a mandate to define and build new platform capabilities and initiatives from the ground up. You will own how this platform scales to many different guest and host use cases, and support business outcomes on guest and host services. You will partner with a cross-functional team of engineers, designers, data scientists, marketplace businesses and operations to build and scale these capabilities. You will also work closely with external enterprise partners and identit

GitRestAIGo
A
📍 United States· Full-time· Remote
✓ Quality checkedCompany trend -98.9%

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: BizTech fosters culture and connection at Airbnb by providing reliable corporate tools, innovative products, and technical support for all teams. We drive technical breakthroughs and strategies that redefine what it means to belong anywhere, delivering greater value for the business and our people. The Global Operations team at BizTech manages production services across Airbnb’s corporate environment, delivering reliable operations through Observability, Incident Management, Core Operations, and AI-enabled automation. We partner across BizTech to scale service quality, efficiency, and resilience. The Difference You Will Make: As a Senior Staff Engineer in Operations, you will lead and mentor a high-performing team to scale our AI-enabled operations model and deliver AIOps solutions that streamline operational workstreams and help BizTech teams focus on their core work with confidence. Ops owns triage and resolution, proactive monitoring across networks, systems, applications, and cloud services via a homegrown observability platform, and drives process excellence through automation and shift-left programs. You will set the technical bar, model operational excellence, and ensure high-quality, reliable service. Your scope includes leading projects ac

PythonAWSCI/CDAI
A
📍 United States· Full-time
✓ High-confidence listingCompany trend -98.9%

From $139K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: The Cities team leads the work necessary to implement the regulatory products and processes needed globally to comply with regulations, and does so in a manner that also sustainably supports Airbnb’s growth. The Difference You Will Make: We are seeking an operator who is exceptionally effective, entrepreneurial, collaborative, and an excellent communicator. In this role, you will help us scale regulatory compliance strategies and programs for jurisdictions, presenting to cross-functional peers and leadership. You will be the accountable owner for compliance programs, aligning strategy and execution across disparate stakeholders. You will have an eye towards scale, testing, and iterating to further the capacity of the team. You are both scrappy and polished, enabling you to move quickly while bringing stakeholders along. Ultimately your work will support our Stays business and partnerships with jurisdictions around the world, keeping Airbnb a trusted community. A Typical Day: Develop and drive regulatory initiatives that unlock supply growth and proactively address risks Lead the development and execution of successfully scaled programs across discrete compliance verticals. Create an operational rhythm and manage cross-functional stakeholders, ensuring initiatives are on track, and maintaining project documentation Analyze strategic opportunities for risk reduction across jurisdictions, partner with Engineering, Data Science, Policy and Legal to align roadmaps, and drive successful execution with measurable impact Support strategic projects to drive efficiency and e

SQLAIGoRust
S
📍 Seattle, Washington, United States· Full-time
✓ Quality checkedCompany trend -95.2%

Who we are About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies—from the world’s largest enterprises to the most ambitious startups—use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone’s reach while doing the most important work of your career. About the team The Support Experience group develops and applies technology at all points of the user support journey to solve customer problems at scale, keeping millions of business running and unlocking growth across Stripe’s product suite. What you’ll do As a Product Lead for Support Experience, you will be devising strategy, developing product requirements, and driving execution for critical initiatives that create a world-class support experience for all of Stripe’s customers and users. You’ll be at the forefront of applied AI, solving problems for businesses and consumers, and redefining what great can look like. You’ll be leading and growing a team of experienced Product Managers who have a track record of delivering high-impact products that elevate the support experience for Stripe’s users and our user-facing support teams. Support is a high-visibility area at Stripe, and you’ll need to be comfortable orienting company leadership around your goals. Responsibilities Own and drive the product roadmap for the future of conversational AI and human support at Stripe Shape strategy, steer product requirements, and hold a high bar for the execution of high-impact initiatives that impact key segments and top customers. Partner with Stripe’s AI teams to unlock opportunities for serving users more effectively Build strong relationships with senior leaders across Operations to continually uplevel our human support functions Grow and coach a glob

O
Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team The Product Marketing team shapes how OpenAI brings its research, models, and products to market. We work across Research, Product, Engineering, Sales, Communications, and Marketing to translate technical advances into clear customer value, compelling market narratives, and go-to-market strategies that drive meaningful adoption. About the Role We’re looking for a senior product marketing leader to shape how OpenAI’s models and research are understood and adopted around the world. You’ll work directly with frontier research teams to understand emerging capabilities and translate them into compelling product strategies, market narratives, and customer experiences. Your scope will span frontier models, specialized models for cybersecurity and life sciences, multimodal capabilities, and the API portfolio that makes these systems accessible to developers and businesses. You’ll build and lead the team responsible for helping customers understand what our models can do, how they’re evolving, and how to deploy them responsibly. In this role, you will: Define the product marketing strategy for OpenAI’s models, research advances, and API portfolio. Embed with Research, Product, and Engineering to understand model capabilities, evaluations, limitations, and technical tradeoffs. Shape how OpenAI explains advances in AI to developers, business leaders, and the broader market. Lead positioning, launches, demonstrations, and adoption strategies across frontier, specialized, and multimodal models. Help customers navigate model selection, API access, privacy, security, and responsible deployment. Bring customer and market insights into research and product decisions. Partner with Sales, Solutions, Partnerships, and regional teams to develop customer narratives, use cases, and enablement. Work with Communications, Safety, Policy, and Legal to ensure technical claims are accurate and grounded. Build and lead a high-performing product marketing team and define success ac

AWSRestAIGo

Related career options

Similar roles with stronger pay

Client Service Associate

Demand 46/100 · 8 jobs

$840K – $840K/yr

Salary →
Director of Product

Demand 43/100 · 6 jobs

$382.5K – $382.5K/yr

Salary →
Physical Design Engineer

Demand 43/100 · 8 jobs

$300K – $300K/yr

Salary →
Sr. Engineer

Demand 42/100 · 7 jobs

$300K – $300K/yr

Salary →
Senior Director

Demand 38/100 · 30 jobs

$278.9K – $278.9K/yr

Salary →
Senior Product Designer

Demand 30/100 · 11 jobs

$255.7K – $255.7K/yr

Salary →
🔔

Get new senior lead software engineer machine learning jobs in United States by email

Daily job updates · Unsubscribe anytime