Jobs in United States

Senior Manager Software Development in United States

1,941 active opportunities · Updated October 2026

Explore current senior manager software development jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 New York, United States
✓ High-confidence listingCompany trend +671.4%

$230.9K – $384.8K/yr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY Pfizer Commercial Oncology is introducing the world to the next era of cancer care. With a growing portfolio of novel therapies, industry-leading R&D, and a goal of delivering eight breakthroughs by 2030 across major cancer types, we're translating cutting-edge science into market-shaping impact. Here, you'll partner with exceptional colleagues across scientific, medical, and manufacturing teams, backed by advanced digital and AI-enabled infrastructure and the authority to accelerate medicines from discovery to delivery. Guided by our values of courage, excellence, equity, and joy, you'll have the opportunity to stretch your skills and build a career that evolves with you—across teams, roles, and the Pfizer enterprise. Join us to make history — for patients, for their families, for the future. The US Precision Medicine Thoracic Franchise is entering its most consequential — and most complex — growth chapter. Our in-line thoracic portfolio spans two biomarker-defined populations: LORBRENA (lorlatinib) for adults with ALK-positive metastatic non-small cell lung cancer (NSCLC), and the BRAFTOVI + MEKTOVI (encorafenib + binimetinib) regimen for BRAF V600E-mutant metastatic NSCLC. Both sit inside a molecularly driven treatment landscape where the right patient is identified by a biomarker signature. Winning here means mastering precision targeting: reaching narrow, high-value, genomically defined patient populations through the exact clinicians who test for and treat them. This is a people-management leadership role that demands a strong enterprise leader — one fluent in both commercial strategy and AI-enabled execution, and able to think and operate at the enterprise level. The colleague who leads this team will set a multi-year strategic vision, make thoughtful trade-off and resource-prioritization decisions across two brands, and influence senior leadership across the wider organizati

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📍 Remote, United States· Remote
✓ High-confidence listingCompany trend -8%
Quick readStrong listing-quality and freshness signals

NVIDIA DGX Cloud is an AI Factory designed to power the next generation of AI and industrial-scale breakthroughs. As a Principal Engineer for Security Architecture, within our Security Engineering organization, you will own a core security domain of the AI factory: the architecture, the paved road that delivers it, and much of the code underneath. You will hold the security design bar across DGX Cloud from inside the teams doing the building, and this is a founding seat on a new team. Security Engineering is a new organization at DGX Cloud, accountable for the security outcome of the platform, and Security Architecture is the function inside it that holds the design bar. Security here is fleet horizontal and stack vertical, so your work will cross every DGX Cloud engineering organization: you will embed with the teams building GPU clusters, control planes, and services, join their designs as a participant rather than an approver, and leave behind systems in which an entire class of risk is no longer possible. There is no architecture review board here and no approval queue. You are a senior IC with deep security domain knowledge, and the security bar holds because you helped set it and then helped ship it. What You Will Be Doing: Own a Security Domain End to End: Take architectural ownership of a core domain of DGX Cloud security, from the design through the system running in production. That could be tenant and GPU workload isolation, workload identity, infrastructure and network, supply-chain provenance, hardened baselines and patching, or deploy-time policy and admission control. Embed with the Teams Building It: Join the design early, write the code, and help land it. The posture is not "you did this wrong." It is "here are the considerations we need to meet, I will help, let's go to work." Build Paved Roads, Not

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📍 California, USA - Remote, United States· Remote
✓ High-confidence listingCompany trend +90.9%
Quick readStrong listing-quality and freshness signals

Job Requisition ID # 26WD100708 Director, Expansion & Strategic Accounts D&M We are seeking a strategic Director Expansion & Strategic Accounts to lead a regional sales organization focused on the Design and Manufacturing industry. This leader will drive revenue growth, develop high-performing teams, strengthen customer and partner relationships, and execute sales strategies aligned with Autodesk’s business objectives. What You’ll Do Lead, coach, and develop a high-performing sales team focused on revenue growth and customer expansion. Develop and execute territory and industry sales strategies aligned to Autodesk priorities. Drive quota attainment through pipeline discipline, forecasting, deal inspection, and accountability. Build strong customer, partner, and internal relationships to identify growth opportunities and deliver outcomes. Partner across sales, technical sales, customer success, partner management, marketing, finance, and product teams to improve execution. Create a culture of ownership, collaboration, inclusion, and continuous improvement. What You Bring Experience leading sales teams in enterprise software, SaaS, technology, or a related B2B environment. Track record of achieving revenue targets and building predictable sales performance. Strong understanding of territory planning, pipeline generation, forecasting, account planning, and customer expansion. Experience with direct and indirect sales channels, including partner ecosystems. Ability to lead through influence across matrixed teams and senior stakeho

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📍 San Francisco, California, United States
✓ High-confidence listingCompany trend +212.5%
Quick readStrong listing-quality and freshness signals

Our Purpose Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential. Title and Summary Vice President, Software Engineering Overview Decision Stream is Mastercard's next-generation AI-native decisioning platform, designed to power intelligent, real-time decisions across fraud, authentication, payments, and risk. Built with a startup mindset and enterprise-scale ambition, the platform combines innovation, speed, and engineering excellence to redefine decisioning across Mastercard's global ecosystem. We are seeking a visionary and hands-on VP of Software Engineering to help build and scale the platform. This leader will partner closely with Product, Architecture, AI, and Platform Engineering teams to drive technology strategy, architecture, engineering execution, and organizational growth. What You'll Do Lead Through Technical Excellence • Serve as a senior technology leader and role model for engineering teams. • Drive architecture, design, and technology decisions across distributed systems, streaming, AI, and cloud-native platforms. • Engage deeply with engineers, architects, and product leaders to solve complex technical challenges. • Influence engineering standards, software quality, and operational excellence. Build and Scale the Platform • Help shape and deliver a highly scalable, resilient, and secure decisioning platform operating at Mastercard scale. • Balan

KubernetesAIRecruitment
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📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$109.7K – $141.9K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Oncology department at Gilead Sciences is seeking an experienced and motivated Associate Scientist/ Senior associate Scientist with exceptional technical skills to support research programs focused on the discovery and development of novel therapies that mobilize the immune response against cancer. The successful candidate will be instrumental in conducting experiments and help develop novel assays to test therapeutic hypotheses and advance immune engager therapeutic candidates to selectively target tumors. Our highly diverse, collaborative, and interdisciplinary research teams utilize state-of-the-art technologies and innovative methodologies to advance novel immuno-oncology therapies in

Recruitment
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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -93.7%

$165K – $270K/yr

Quick readStrong listing-quality and freshness signals

Drata is building the trust layer between great companies - automating compliance, managing risk, and helping organizations prove trust continuously as they scale. We're Dratanauts: a global crew of 600+ professionals united by a culture that rewards integrity, ownership, and raising the bar, no matter where in the world we're working from. Why Join the Drata Team? At Drata, you're not maintaining legacy compliance software - you're building the agentic AI platform defining what trust looks like for the next generation of companies. Here's what makes the work itself worth showing up for: Problems without a playbook: You'll work at the edge of AI and security, building agentic governance, continuous compliance, and real-time trust verification to solve problems that don't have an established answer yet. You're writing it as you go. Real ownership, not just process: Our values center on owning outcomes and raising the bar, not checking boxes. You're expected to have opinions and back them. A seat at the table: Your perspective is unique and valued. Open debate and diverse viewpoints are built into how decisions actually get made here, at every level. Growth at rocketship speed: Drata is scaling fast, which means scope grows fast too. High performers get more ownership, visibility, and experience. A crew, not just coworkers: Dratanauts consistently describe a "come as you are" culture with sharp, curious people—the kind of team that makes hard problems genuinely fun to solve. See what they say here and follow us on LinkedIn for company news, employee stories, and career updates. Job Summary: Drata is looking for a Staff Data Engineer! This person will be a key member of the growing data team, supporting one of the fastest growing B2B SaaS startups to achieve unicorn status. At Drata, we’re on a mission to help build trust across the internet! Data accuracy is an essential cornerstone of our mission. We are looking for a senior data engineer that can help us strategize

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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the Role As Head of Finance - Data Centers, you will be the finance leader for OpenAI’s self-built data center efforts. You will partner with teams across infrastructure, real estate, energy, construction, procurement, and finance to turn proposed sites into sound investment decisions and funded projects. This role spans the full development lifecycle: evaluating opportunities, building investment cases, forecasting capital needs, managing construction budgets, and helping determine how projects should be financed. You will give leadership a clear view of project economics, funding requirements, and risks as we build data center capacity at scale. In this role, you will: Lead financial evaluation of proposed data center and related power infrastructure projects, including site economics, development costs, capacity phasing, lifecycle costs, and key risks. Build and own project-level models and capital expenditure forecasts that connect construction schedules, power delivery, equipment procurement, contingencies, and funding needs. Establish capital budgets and financial controls for active builds. Track commitments, actual spending, change orders, and forecasts to completion; identify cost or schedule risks early. Partner with development, engineering, energy, construction, and procurement leaders on decisions that affect cost, timing, and long-term performance. Work with Treasury, Corporate Finance, Tax, and Legal to evaluate financing options, including project or construction debt, leases, joint ventures, and other partnership structures where appropriate. Prepare investment recommendations and capital approval materials for senior leadership, translating complex project details into clear choices and tradeoffs. Build a consistent portfolio view of project costs, cash requirements, milestones, and financial performance. Partner with Accounting and operations teams through project completion and handoff. You might thrive in this role if you have: Prior exper

AWSRestAIRust
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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the Team OpenAI’s User Operations team shepherds our customers’ adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others, to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. Within Premium Support, Dedicated Support Engineers combine deep technical troubleshooting with an enduring understanding of our most strategic customers’ architectures, critical workloads, and business priorities. Through proactive reliability work, ownership during incidents, and AI-powered support capabilities, we help customers operate successfully as their use of OpenAI grows. About the Role We’re looking for a senior leader to build and scale our Dedicated Support Engineering function globally. You will define its strategy, build the team, and establish how we deliver technically rigorous, proactive support for customers running some of the most complex and consequential workloads on OpenAI. This role combines organizational leadership, technical judgment, and executive customer engagement. You will establish a model in which DSEs develop deep customer context, independently advance difficult investigations, anticipate operational risks, and drive issues through resolution. You will also turn what the team learns into improvements that benefit customers across OpenAI. You should bring experience building technical organizations that maintain long-term accountability for enterprise customers. Leadership in Technical Account Management, enterprise Support Engineering, or a comparable technical customer function is particularly rel

AWSRestAIGo
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📍 Austin, Texas, United States· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

About DevRev At DevRev, we're building the future of work with Computer – your AI teammate. Unlike traditional tools, Computer unifies all your data sources, tools, and workflows into a single AI-ready platform, giving employees real-time insights, proactive suggestions, and powerful agentic actions. It extends your existing software with AI-native apps and agents that work alongside your teams and customers – updating workflows, coordinating across teams, and eliminating repetitive work. We call this Team Intelligence: human-AI collaboration that breaks down silos, brings people back together, and frees you to solve bigger problems. Backed by Khosla Ventures and Mayfield with $150M+ raised, DevRev is trusted by global companies across industries. About the team The Applied AI Engineering team ensures our customers get the optimal experience from DevRev. As customers go through their DevRev journey, they may identify needs for integration with existing enterprise systems and services, workflow and process automation, or customization of the DevRev platform to achieve their business objectives. Our team works with customers to understand requirements and design, develop, and implement solutions to meet customer goals. Your mission is to systematically help customers find value with DevRev by developing a thorough understanding of their needs, owning coordination between internal and external stakeholders, and engineering the solution to get the job done. You are a product expert and will use your application development and AI/ML skills to ensure our customers get the most out of the DevRev platform. About the role As a Forward Deployed Architect, you will serve as a hands-on senior technical architect on the Applied AI Engineering team, owning the end-to-end design and delivery of AI-driven business transformation projects. You will work closely with pre-sales teams to scope technical integration and implementation strategies, translating business requirement

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📍 Aliso Viejo, United States· Full-time· Remote
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

About OfficeSpace: OfficeSpace Software provides the leading AI operating system for the built world, that helps teams plan, connect, and perform in the workplace. As a performance-based, PE-backed company, we hire based on merit and a willingness to do what it takes to succeed long-term. You’re a great fit for the role if you’re entrepreneurial, passionate, motivated by building at light speed, and an Agentic AI early adopter. Our world-class teams operate in the US, Canada, and Costa Rica in a culture of trust, respect, growth, and impact. Role Summary: You win new logos. Full stop. As a Enterprise Account Executive, you own the end-to-end motion of bringing new customers into OfficeSpace. You run disciplined, value-led sales cycles with senior decision-makers and use AI-powered tools to prospect smarter, sell faster, and close with confidence. We give you a market-leading platform. You turn it into revenue. What You’ll Do: Own new-logo acquisition across a defined Enterprise territory—build pipeline, run deals, and close. Lead buyer-driven, value-based sales cycles with C-level, VP, and Director stakeholders. Orchestrate AI-assisted prospecting to identify high-intent accounts and create net-new opportunities. Translate workplace, facilities, and real estate challenges into clear, quantifiable business value. Deliver sharp, compelling product demos that connect OfficeSpace capabilities to real-world outcomes. Guide AI-generated proposals, pricing models, and forecasts—ensuring accuracy, clarity, and impact. Negotiate contracts and commercial terms with confidence and discipline. Maintain rigorous pipeline hygiene and forecasting using Salesforce and revenue intelligence tools. Partner with Marketing and Business Development to accelerate deal velocity and improve win rates. Share frontline market feedba

AgileAIGoRust
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📍 Atlanta, Georgia, United States· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

About OfficeSpace: OfficeSpace Software provides the leading AI operating system for the built world, that helps teams plan, connect, and perform in the workplace. As a performance-based, PE-backed company, we hire based on merit and a willingness to do what it takes to succeed long-term. You’re a great fit for the role if you’re entrepreneurial, passionate, motivated by building at light speed, and an Agentic AI early adopter. Our world-class teams operate in the US, Canada, and Costa Rica in a culture of trust, respect, growth, and impact. About the role: OfficeSpace is looking for a Director of Sales Development to build the next generation of our pipeline engine. You will own inbound- and outbound-sourced pipeline across new-logo and expansion accounts, lead our strategic ABX motion, and develop SDRs and Senior SDRs into high-performing GTM talent. You'll shape how people and AI agents work together—using automation to expand capacity while keeping judgment, relationships, and buyer experience human-led. This is a builder role. You'll partner closely with Sales, Marketing, Revenue Operations, Finance, and Enablement to turn revenue goals into a focused operating system that improves account penetration, conversion, pipeline productivity, and talent development as OfficeSpace moves upmarket. What you'll do: Own the pipeline engine. Translate revenue targets, pipeline coverage, conversion rates, and productivity assumptions into SDR capacity, quotas, territories, coverage, and investment decisions. Build a high-performing team. Lead, coach, and develop SDRs and Senior SDRs against clear goals for pipeline, conversion, quality, productivity, and progression. Lead strategic ABX. Turn account segments, intent, buying-group signals, whitespace, and market triggers into focused action across Mid-Market and Enterprise new-logo and expansion accounts. Build depth in priority accounts. Establish disciplined account-planning motions across research, contact ma

AgileAIGoRust
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📍 Boston, Massachusetts, United States· Full-time
✓ High-confidence listing

From $91.1K/yr

Quick readStrong listing-quality and freshness signals

We take play seriously. We’re looking for curious adventurers ready to find their party, fueled by imagination and drive to build what’s never been built before. At Hasbro and Wizards of the Coast, you’ll collaborate with passionate teams to reimagine our iconic brands and create experiences that spark joy, connection, and community through the magic of play. This is your chance to shape legendary play that lasts a lifetime. Reliable workplace technology enables teams to do their best work. This role focuses on maintaining and improving that reliability across devices, collaboration systems, and workplace technology environments. The Workplace Technology Support Engineer - Executive Support helps maintain the stability, performance, and continuous improvement of workplace technology across the organization, with a main focus on our executive leadership team. This will serve as the main point of contact for issues in the executive space. The role will need to be available to travel to support events, shows, presentations, and calls. You'll work closely with platform engineering, security, networking, and other internal teams to diagnose advanced issues, maintain operational standards, and translate recurring problems into scalable solutions through standardization, documentation, automation and AI-assisted operational improvements! Effective from the date that Hasbro opens its new Boston location, this position will be onsite Monday – Friday at Hasbro’s new HQ location in Boston, MA. In the interim, this position will be onsite Monday – Friday at Hasbro’s HQ in Pawtucket, RI. What You'll Do Executive Support Primary technology support resource for executives and senior leadership, delivering responsive, high-touch technical support across office, remote, and travel environments. Provide white-glove support for executive workstations, laptops, mobile devices, collaboration platforms, and workplace technologies while maintaining exceptional custom

GitAIGoSEM
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📍 Boston, Massachusetts, United States· Full-time
✓ High-confidence listing

From $143.9K/yr

Quick readStrong listing-quality and freshness signals

We take play seriously. We’re looking for curious adventurers ready to find their party, fueled by imagination and drive to build what’s never been built before. At Hasbro and Wizards of the Coast, you’ll collaborate with passionate teams to reimagine our iconic brands and create experiences that spark joy, connection, and community through the magic of play. This is your chance to shape legendary play that lasts a lifetime. Hasbro is updating the way work is conducted across supply chain, go to market, finance, consumer products, and licensing. Our mature RPA practice on Automation Anywhere is now growing to include agentic AI. These systems interpret unstructured inputs, invoke tools, and perform complex workflows with human oversight where needed. We are looking for a Principal Automation Specialist to act as the senior technical expert in this initiative. This hands-on leadership role involves setting the architectural vision for our intelligent automation platform, building the most complex elements, and raising the team’s technical standards. Responsibilities As a Principal Automation Specialist, your responsibilities will include: Architect and build agentic automation: LLM-orchestrated workflows that combine deterministic RPA with reasoning based on data patterns, tool/API calling, and structured output. Extend our Automation Anywhere estate — migrate brittle, screen-scraped bots to API- and agent-based patterns and decide deliberately when a task should stay deterministic. Build the reliability layer that makes agents safe to run in production: evaluation harnesses, regression suites, confidence thresholds, human-in-the-loop approval gates, fallback paths, and audit logging. Own the integration surface — connect agents to ERP (SAP), data platforms, ticketing, and internal APIs via standardized tool interfaces (e.g., MCP servers, REST/GraphQL, event-driven triggers). Apply document and language intelligence to workflows that resisted cl

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📍 New York, United States· Full-time· Remote
✓ High-confidence listing

From $192K/yr

Quick readStrong listing-quality and freshness signals

Zscaler (NASDAQ: ZS) accelerates digital transformation so customers can be more agile, efficient, resilient, and secure. The Zscaler Zero Trust Exchange™️ platform protects thousands of customers from cyberattacks and data loss by securely connecting users, devices, and applications in any location. Distributed across 160+ public exchanges globally and thousands of private exchanges at the edge, the SASE-based Zero Trust Exchange is the world’s largest in-line cloud security platform. We believe the future of work is Human + AI and are building an AI-native enterprise where human potential is amplified by machine intelligence to solve the world’s hardest security challenges. Driven by deep customer obsession, we are committed to the mission, outcome, and to each other. We bring these commitments to life through three core behaviors: ownership and collaboration, trust through outcomes and impact, and a challenge culture with ongoing feedback. Ready to make an impact at the company pioneering security transformation in the AI era? Join us at Zscaler. Role We are looking for a Global Alliance Director - Accenture to join our Global GSI Advisory Team. This is a role based in the Americas, reporting to the Senior Director, Alliance Partners. You will lead the end-to-end Global Partnership with Accenture, building key relationships and developing joint offerings that drive transformational, incremental net new opportunities for Zscaler. You will serve as the primary architect for our global Accenture business plan, ensuring mutual revenue growth and strategic alignment across our Security, Network, and Cloud practices. What you’ll do (Role Expectations) Create and execute a global Business Plan to expand the Accenture partnership and brand footprint globally Lead the end-to-end Global Partnership by developing joint offerings that can be leveraged by the field sales organization to drive net new opportunities Drive Zscaler revenue growth while ensuring Accenture meets th

AWSGitAgileAI
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📍 Miami, Florida, United States· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

About Us OpenFX is on a mission to move money as freely as data, unrestricted by time zones, banking hours, or legacy systems. We are building the infrastructure that will power the next generation of cross-border payment systems for institutions. The team's execution has been exceptional, and we're scaling at a remarkable pace. Our stellar early team comes with experience in companies like J.P. Morgan, Goldman Sachs, FalconX, Paypal, Affirm, Polygon, Kraken, Nium & others. We’re backed by Accel, Lightspeed, NfX and other top-tier investors. Role Overview We're seeking an exceptional Americas Legal Counsel to serve as a strategic partner and legal advisor across our business, with a particular focus on financial products and partnerships. This role combines the intellectual challenge of navigating cutting-edge financial technology with the opportunity to shape legal strategy in the early stages at a high-growth company. You'll work on some of the most complex and interesting problems at the intersection of cross-border payments, cryptocurrency, foreign exchange and technology—providing pragmatic, business-oriented counsel that enables rapid growth while managing risk effectively. The ideal candidate is a team player who is energized by a high-growth environment and translating complex legal requirements and legal ambiguity into clear, actionable strategies. You move quickly with sound judgment, and excel as a trusted senior advisor to product, engineering, compliance, and business teams. Key Responsibilities: Product Legal Advise product and engineering teams on the legal and regulatory aspects of product design, development, and launch, with a particular focus on payment and banking products Translate complex regulatory requirements into clear guidance that helps teams build compliant products while growing rapidly Regulatory & Licensing Strategy Partner closely with business teams and compliance to develop and execute licensing and market entry strategies

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