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Senior System Engineer Cloudflare Hyperdrive in California

54 active opportunities · Updated October 2026

Explore current senior system engineer cloudflare hyperdrive jobs in California. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 California, Fremont 47900 Bayside Pkwy, United States· Hybrid
✓ High-confidence listingCompany trend +364.7%
Quick readStrong listing-quality and freshness signals

Work Flexibility: Hybrid or Onsite Stryker is hiring a Senior Quality Engineer to join our Neurovascular division. This is a hybrid r ole based in Fremont, CA or Salt Lake City, UT . As the Senior Design Quality Engineer , you will be actively involved in Product Risk Management, Post Market Surveillance, Design Control and Product Quality Improvement. You will be involved in a fast-paced mix of short design change efforts and will be responsible for product risk management and adherence to design control requirements throughout the product lifecycle. You will be responsible for ensuring that post market data and feedback is channeled into the risk management system throughout the product lifecycle. You will make regular use of problem-solving tools and statistical analysis to analyze and trend data and provide quality input into technical investigations, perform test method development and validation, design verification, risk assessment and design reviews. You will be responsible for supporting product testing and failure analysis, writing protocols and reports, creating and maintaining risk files and assessing the impact of necessary changes to our products. You will lead initiatives to increase sales and improve the customer experience of our devices. Neurovascular (NV) products push the boundaries of technology to meet ever increasing product performance requirements, making the goal of assessing and demonstrating, safety, performance and compliance an exciting challenge. What You Will Do Develop qualification plans, protocols, and reports for new products, existing products, components, and subassemblies. Execute product testing, inspection, verification, and validation activities to support design and quality objectives. Perform failure investigations and root cause anal

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📍 California, United States of America, United States
✓ High-confidence listingCompany trend +1850%
Quick readStrong listing-quality and freshness signals

We anticipate the application window for this opening will close on - 10 Oct 2026 Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72+ million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact. A Day in the Life The Neuromodulation Research & Development organization develops therapies and technologies that address chronic pain and other neurological conditions. Within the Interventional Pain portfolio, teams focus on minimally invasive therapies used to treat musculoskeletal pathologies, including vertebral compression fractures, nerve pain, metastatic bone tumors, and benign bone tumors. This role supports the development of system-level verification and validation strategies for new products and enhancements across mechanical, electrical, and software components. This position is based in Santa Clara, California, and follows an onsite work model. No travel is required for this role. As a Research & Development Test Engineer, you will lead and execute verification and validation activities that support the development of interventional pain therapies and associated medical device systems. You will collaborate with cross-functional partners to define test strategies, evaluate product performance, manage technical risks, and generate evidence needed to support product development and regulatory requirements. Primary Responsibiliti

RecruitmentHR
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📍 California, United States
✓ High-confidence listing

$98.4K – $147.6K/yr

Quick readStrong listing-quality and freshness signals

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. We are seeking a Senior Mechanical Engineer to support new product development in genomics instrumentation. This is a highly technical mechanical design role focused on the development of custom mechanisms, precision motion systems, and electromechanical assemblies used in advanced instrumentation. The ideal candidate will be an engineer with experience designing motorized mechanisms and precision motion systems, including a strong understanding of system requirements, motion architecture, controls integration, structural design, and performance validation. The ideal candidate also has experience developing motion solutions from requirements through implementation and understands the engineering principles behind achieving precise, reliable motion in complex systems. Responsibilities Design and develop custom mechanical mechanisms for use in genomics instruments, including motion systems, precision assemblies, and fluidic or sample‑handling components. Integrate mechanical designs with electrical, firmware, and control systems Create and maintain 3D CAD models, engineering drawings, and support

Artificial IntelligenceAI
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📍 California, United States
✓ High-confidence listing

$141.6K – $212.4K/yr

Quick readStrong listing-quality and freshness signals

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Summary The Staff Data Engineer is a seasoned, hands-on engineer who designs, builds, and scales data products on our cloud lakehouse, powering analytics, reporting, and AI/ML across Illumina. We are looking for someone with strong proficiency in Python, SQL, and data modeling, a solid understanding of distributed systems and system design who has built and scaled data products on modern cloud platforms such as Databricks and Snowflake. This is a hands-on, senior individual-contributor role with end-to-end ownership and leadership spanning multiple domains such as Supply Chain, Manufacturing and Quality, including mentoring engineers on our global (India-based) team. Responsibilities Partner across business, AI, and platform teams translating domain needs (e.g., SAP, Manufacturing, Quality) into well-modeled, governed and scalable data products. Design, build, and scale end-to-end data products on Databricks (and interoperating with Snowflake) — from ingestion through curated, analytics-ready datasets following a medallion (Bronze/Silver/Gold) architecture. Develop reusable frameworks, libraries, and

PythonSQLAWSGit
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📍 California, United States of America, United States
✓ High-confidence listingCompany trend +103.7%

$162K – $225K/yr

Quick readStrong listing-quality and freshness signals

Senior Software Engineer, Cloud Services Description - Who We Are HP IQ is HP’s new AI innovation lab. Combining startup agility with HP’s global scale, we’re building intelligent technologies that redefine how the world works, creates, and collaborates. We’re assembling a diverse, world-class team—engineers, designers, researchers, and product minds—focused on creating an intelligent ecosystem across HP’s portfolio. Together, we’re developing intuitive, adaptive solutions that spark creativity, boost productivity, and make collaboration seamless. We create breakthrough solutions that make complex tasks feel effortless, teamwork more natural, and ideas more impactful—always with a human-centric mindset. By embedding AI advancements into every HP product and service, we’re expanding what’s possible for individuals, organisations, and the future of work. Join us as we reinvent work, so people everywhere can do their best work. About The Role As a Senior Software Engineer, Cloud Services, you will create scalable, reliable backend systems that support HP IQ's mission to transform the way people work. We value how we work as much as what we deliver. Our journey of continuous learning and evolution requires a flexible and resilient services platform that fosters innovation, experimentation, and adaptation. To enable this, we focus on designs and tools rooted in strong engineering principles like abstraction, composition, virtualization, automation, and iterative development cycles. What You Might Do Design, develop, and maintain backend services and RESTful APIs using Java and Spring Boot. Write clean, efficient, and well-tested code following established best practices. Collaborate with frontend developers, product managers, and other engineers to deliver end-to-end features. Integ

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📍 California, California, United States· Full-time
✓ Quality checkedCompany trend -100%

Who Are We? Postman is the world’s leading API platform, used by more than 45 million+ developers and 500,000 organizations, including 98% of the Fortune 500. Postman is helping developers and professionals across the globe build the API-first world by simplifying each step of the API lifecycle and streamlining collaboration—enabling users to create better APIs, faster. The company is headquartered in San Francisco and has offices in Boston, New York, Austin, Tokyo, London, and Bangalore - where Postman was founded. Postman is privately held, with funding from Battery Ventures, BOND, Coatue, CRV, Insight Partners, and Nexus Venture Partners. Learn more at postman.com or connect with Postman on X via @getpostman. P.S: We highly recommend reading The "API-First World" graphic novel to understand the bigger picture and our vision at Postman. The Opportunity (Summer 2026 AI Internship - Applications Open Now) We're seeking an AI Engineer Intern to work alongside our AI team on large-scale AI and Agentic systems from data pipeline to production deployment. This role is scoped for someone with foundational experience who wants to deepen it: you'll own discrete pieces of real systems under the mentorship of senior engineers, not shadow work or isolated coursework-style projects. What You'll Do You’ll work directly with the AI team, taking responsibility for well-scoped pieces of real systems, with mentorship from senior engineers. Benchmarks & Evaluation Contribute to APIFlow-Bench , our open-source benchmark for real API-development work: design and review benchmark tasks and their mock API environments, extend the evaluation harness and task-generation pipeline in Python, and help maintain the public multi-model leaderboard with statistical confidence intervals. Help build a new action-level AI safety benchmark: instead of grading what a model says, it scores what an agent actually does inside a simulated enterprise API environment. You’ll work on scenari

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📍 California, USA - Remote, United States· Remote
✓ Quality checkedCompany trend +90.9%

Job Requisition ID # 26WD97363 Position Overview We are seeking a Principal Software Engineer – Backend to join Autodesk’s Enterprise Data Management (EDM) organization within the COO-GET Engineering group. This is a senior individual contributor role operating at the Principal (P4) level , expected to drive technology direction for large, complex, and business-critical backend and distributed systems . This role is anchored in backend software engineering excellence : designing, building, and evolving scalable services, APIs, and event-driven systems that operate at enterprise scale. As a Principal Engineer, you will work with high autonomy and ambiguity , shape long-term architecture, and influence multiple teams and domains. Familiarity with data engineering concepts is valuable, but backend systems, service design, and distributed systems are the core competencies. You will function as a technical authority and force multiplier—guiding design decisions, setting standards, and ensuring Autodesk’s core data services are reliable, resilient, and evolvable over time. Responsibilities Provide principal-level technical

PythonAWSAI
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📍 California, United States
✓ High-confidence listingCompany trend +365.2%
Quick readStrong listing-quality and freshness signals

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 122,000 colleagues serve people in more than 160 countries. JOB DESCRIPTION: At Lingo, we’re building a groundbreaking health platform that combines continuous biosensor data, real-time analytics, and personalized insights to help people live fuller, longer, and healthier lives. Our systems ingest millions of sensor readings daily, powering experiences for consumers and partners worldwide, with the reliability and scalability of cloud-native, enterprise-grade platforms. At Abbott, you can do work that matters, grow, and learn, care for yourself and family, be your true self and live a full life. You’ll also have access to: Career development with an international company where you can grow the career you dream of. Employees can qualify for free medical coverage in our Health Investment Plan (HIP) PPO medical plan in the next calendar year An excellent retirement savings plan with high employer contribution Tuition reimbursement, the Freedom 2 Save student debt program and FreeU education benefit - an affordable and convenient path to getting a bachelor’s degree. A company recognized as a great place to work in dozens of countries around the world and named one of the most admired companies in the world by Fortune. A company that is recognized as one of the best big companies to wor

ReactGraphqlAIKotlin
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📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$243.1K – $314.6K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description At Gilead, our pursuit of a healthier world for all people has led to transformative advances in HIV treatment and prevention, a cure for hepatitis C, and important progress across viral, inflammatory, and oncology diseases. We set bold ambitions in our work to address some of the world’s most urgent public health challenges and improve the lives of patients around the globe. Position Overview The Gilead Patient Solutions (GPS) team operates in almost 140 low-and lower-middle income countries across the world to champion innovative solutions that improve patient outcomes, promote health system sustainability, strengthen infrastructure and uplift communities. The Senior Dir

Recruitment
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📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$115.3K – $149.2K/yr

Quick readStrong listing-quality and freshness signals

We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet. Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows. Job Description Position Summary The Senior IT Quality Engineering Specialist serves as the technical lead for the Kite Laboratory Information Management System (KLIMS) within North America West Coast (El Segundo). This role is responsible for the operational stability, compliance, maintenance, enhancement, and technical governance of the LabVantage platform and associated integrations. The position partners closely with Quality Control, Manufacturing, Validation, Infrastructure, and Kite Business stakeholders to ensure reliable and compliant laboratory operations. Key Responsibilities System Administration & Operational Support • Provide day-to-day administration and technical support for KLIMS and related

JavaSQLRecruitment
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📍 California, United States of America, United States
✓ High-confidence listingCompany trend +1850%
Quick readStrong listing-quality and freshness signals

We anticipate the application window for this opening will close on - 29 Sep 2026 Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72+ million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact. A Day in the Life This is a field based position. We are seeking a committed professional to join our team, required to reside within the territory and drive to multiple accounts throughout the region. A valid driver's license is essential for this role, which also includes travel outside the territory, presenting opportunities for broader engagement. Across our global Neuroscience organization, we advance care for some of medicine’s most complex neurological and spinal conditions by combining innovative technology, data-driven insights, and deep clinical expertise. Within this organization, our Neurovascular operating unit is dedicated to advancing the treatment of stroke, brain aneurysms, and other vascular disorders through innovative endovascular technologies. By partnering with physicians and health systems, we help improve patient outcomes through solutions designed for revascularization, embolization, and precise intervention, supporting clinicians in delivering timely, effective care throughout the patient journey. Check us out on LinkedIn: Medtronic Neurovascular A Senior Terr

AccountingFinanceRecruitmentHR
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📍 California, United States
✓ High-confidence listingCompany trend +671.4%

$68.6K – $114.3K/yr

Quick readStrong listing-quality and freshness signals

Position Summary Pfizer is seeking a motivated Senior Associate Scientist to join the In Vivo Pharmacology group within the Oncology Research Unit, with a focus on antibody-drug conjugate (ADC) programs, but including other large molecule and small molecule programs. This role supports the execution of in vivo oncology studies that enable ADC discovery and preclinical development, including efficacy, tolerability, pharmacodynamic, and sample collection workflows. The ideal candidate will demonstrate strong technical aptitude, careful attention to detail, and a commitment to animal welfare, compliance, and high-quality study execution. The Senior Associate Scientist is expected to contribute as a dependable technical team member while building scientific understanding of oncology pharmacology and ADC-specific study requirements. Position Responsibilities Execute in vivo oncology studies supporting discovery programs using a variety of in vivo models including human cell line- derived, patient-derived xenograft, syngeneic models as appropriate with minimum guidance from study leads. Perform routine and advanced in vivo procedures, including tumor measurements, body weight monitoring, test article administration (IV, PO, subQ, IP dosing), clinical observations, and sample collection. Perform routine in vitro tissue culture procedures Support pharmacology studies evaluating efficacy, tolerability, pharmacodynamic biomarkers, dosing schedules, and combination approaches. Prepare study materials, confirm dosing and sampling schedules, and ensure study activities are performed according to approved protocols and SOPs. Maintain accurate, timely, and compliant study records using approved electronic data capture and documentation systems. Communicate study observations, technical issues, animal welfare concerns, and timeline risks promptly to managers and study line leads. Collabo

AIRecruitment
A
📍 California, United States
✓ High-confidence listingCompany trend +365.2%
Quick readStrong listing-quality and freshness signals

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 122,000 colleagues serve people in more than 160 countries. JOB DESCRIPTION: Job Title Senior Medical Writer / Senior Project Manager, Clinical Evaluation Working at Abbott At Abbott, you can do work that matters, grow, and learn, care for yourself and your family, be your true self, and live a full life. You’ll also have access to: Career development with an international company where you can grow the career you dream of. Employees can qualify for free medical coverage in our Health Investment Plan (HIP) PPO medical plan in the next calendar year. An excellent retirement savings plan with a high employer contribution. Tuition reimbursement, the Freedom 2 Save student debt program, and FreeU education benefit - an affordable and convenient path to getting a bachelor’s degree. A company recognized as a great place to work in dozens of countries worldwide and named one of the most admired companies in the world by Fortune. A company that is recognized as one of the best big companies to work for as well as the best place to work for diversity, working mothers, female executives, and scientists. The Oppor

Project Management
I
📍 California, United States· Hybrid
✓ High-confidence listing

$82.5K – $123.7K/yr

Quick readStrong listing-quality and freshness signals

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Position Title: Senior Financial Analyst, R&D Finance Location: San Diego, CA (Hybrid) Reports To: Associate Director, Finance – R&D FLSA Status: Exempt Position Summary: The R&D Finance Business Partner provides finance support for a complex portfolio of R&D functions, programs, strategic initiatives, and R&D leadership team members. The role works with R&D and Finance leadership to translate technical and operational activity into clear financial insight, improve forecast accuracy, evaluate investment trade-offs, and support resource decisions across operating expense, headcount, and capital investment. This position operates as an individual contributor in a matrixed environment with limited day-to-day direction. Success requires strong financial rigor, sound business judgment, clear communication, and the ability to build trusted partnerships while maintaining appropriate financial challenge and discipline. *This is a full-time role, Monday through Friday, with an expectation of 2–3 in-office days per week and additional on-site presence as

Artificial IntelligenceAISapExcel
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📍 California, United States
✓ High-confidence listingCompany trend +190.5%
Quick readStrong listing-quality and freshness signals

We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet. Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows. Job Description The Senior Manager, Kite Safety and Pharmacovigilance provides scientific and strategic leadership for pharmacovigilance activities supporting Kite’s investigational and marketed products. This role serves as a senior pharmacovigilance science expert, leading complex safety analyses, regulatory deliverables, and cross-functional safety strategy execution. Key Responsibilities Aggregate Reporting and Medical Writing Serve as lead author for complex aggregate safety reports, including PSURs, PBRERs, and DSURs, synthesizing global safety data and clinical context Author and review high-impact safety documents supporting regulatory submissions and lifecycle management Safety Analysis and Signal Management <

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