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Python Engineer in San Francisco

115 active opportunities · Updated October 2026

Explore current python engineer jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.

A
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$165K – $247K/yr

Quick readStrong listing-quality and freshness signals

Amplitude is the leading AI analytics platform, helping over 4,700 customers—including Atlassian, Burger King, NBCUniversal, and Square—build better products and digital experiences. With powerful AI Agents embedded across our platform, teams can analyze, test, and optimize user experiences faster than ever. Ranked #1 across multiple categories in G2’s Winter 2026 Report, Amplitude is the best-in-class solution for product, data, and marketing teams. Learn more at amplitude.com . As an organization, we deliver for our customers by living our values. We operate from a place of humility, take ownership of problems and successes, approach challenges with a growth mindset, and put our customers at the center of everything we do. Amplitude’s Commitment to Diversity Equity & Inclusion (DEI): Amplitude believes that diversity enables the creation of better products, improves the ability to solve complex problems, and drives more powerful solutions. We strive to create an environment of inclusion—one focused on psychological safety, empathy, and human connection—that will allow employees of all backgrounds to thrive. About the Role Amplitude's Cloud Platform team builds the systems that every Amplitude engineer relies on every day to ship code — and we're rebuilding them for the AI era. As a Senior Platform Engineer, you'll own medium-to-high-complexity platform projects end-to-end and help shape a platform where AI agents are first-class users alongside humans: kicking off deploys, opening pull requests against infrastructure, and triaging incidents, so a single engineer can get the throughput of a team. You'll partner with Staff engineers and product teams to make Kubernetes effortless across the engineering org, building self-service automation and scalable AWS infrastructure that lets product teams ship faster, safer, and with less cognitive load. If you're excited about building the systems that other engineers will rely on every day, this role is for you. Key Resp

PythonAWSGCPKubernetes
V
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$150K – $210K/yr

Quick readStrong listing-quality and freshness signals

Location: San Francisco, CA (Hybrid) What is Verse? The race to AI has become the race to power. Every breakthrough in artificial intelligence depends on one thing: access to electricity. But across the country, aging grid infrastructure and years-long interconnection queues are slowing the deployment of the data centers that will power the next generation of innovation. Solving this challenge isn't just about energy—it's about unlocking the future of AI. At Verse, we're building the energy intelligence platform for the AI economy. Our software helps the world's largest energy consumers achieve faster, cheaper, and cleaner power by combining real-time control of energy assets with complete visibility into their energy portfolio. Backed by Bessemer Venture Partners, GV, Coatue, and NVIDIA, and built by pioneers in grid-scale batteries, energy markets, and enterprise software, we're redefining how the world's most ambitious organizations access and manage energy. The Role We're seeking an experienced Senior Optimization Engineer to join our Data Science Team. In this role, you will lead the design, development, and deployment of optimization models that power our software platform across applications including electricity markets, renewable energy, and battery energy storage systems. You will be responsible for developing production-grade optimization engines that solve complex operational and planning problems at scale. This role requires deep expertise in mathematical optimization, strong software engineering skills in Python, and experience building optimization models that integrate with production systems. The ideal candidate has significant experience in the energy industry, particularly electricity markets and battery storage optimization. This position emphasizes technical leadership, ownership of complex optimization projects, and collaboration across engineering, product, and commercial teams to deliver high-impact optimization solutions. Key Res

PythonCI/CDAIGo
V
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$150K – $240K/yr

Quick readStrong listing-quality and freshness signals

Location: San Francisco, CA (Remote/Hybrid Available) What is Verse? The race to AI has become the race to power. Every breakthrough in artificial intelligence depends on one thing: access to electricity. But across the country, aging grid infrastructure and years-long interconnection queues are slowing the deployment of the data centers that will power the next generation of innovation. Solving this challenge isn't just about energy—it's about unlocking the future of AI. At Verse, we're building the energy intelligence platform for the AI economy. Our software helps the world's largest energy consumers achieve faster, cheaper, and cleaner power by combining real-time control of energy assets with complete visibility into their energy portfolio. Backed by Bessemer Venture Partners, GV, Coatue, and NVIDIA, and built by pioneers in grid-scale batteries, energy markets, and enterprise software, we're redefining how the world's most ambitious organizations access and manage energy. The Role As a Software Engineer focused on Fleet Telemetry & Control at Verse, you will be working closely with our energy solutions partners to design, implement, and test distributed energy resource controls and telemetry software on customer hardware at sites around the world. You will be part of a dynamic, high-performance team building applications directly on bare-metal or on hardware-level virtualization platforms. As an advanced technical leader in network programming and state management development, engineering teams will look to you for best standards and practices for interfacing with on-premises grid assets using solutions you will build and maintain. Key Responsibilities Foster a culture and mindset of well-designed systems, test-driven software, and transparent communication with a high caliber of mutual respect and consideration for stakeholders Mentor and support career and junior level engineers in their fleet telemetry and control software career development

PythonSQLAIC++
SC
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$240K – $270K/yr

Quick readStrong listing-quality and freshness signals

About the Role At Sigma, we’re not just adding AI—we’re building the future of how people work with data. Our platform already lets users explore billions of rows of data in seconds with a spreadsheet-like interface, analyze and present their data in workbooks, and build data apps and workflows. Now we’re pushing further, applying AI to reshape how people build in Sigma, discover insights, and make smarter decisions—fast. That’s where you come in. As an AI/ML Engineer, you’ll join a growing team focused on building the AI foundation that will power Sigma for the future. Your work will become an integral part of the workflow for the thousands of enterprises that run on Sigma. What You’ll Do Partner with product, design, and engineering teams to identify high-impact AI/ML opportunities Prototype and productionize AI systems that feel intuitive but do a lot under the hood—recommendations, natural language interfaces, agentic workflows, and more Develop and scale AI/ML infrastructure that powers both internal tooling and customer-facing features Tackle novel UX problems at the intersection of AI, BI, and apps What You Bring Bachelor’s degree in Computer Science, Engineering, Mathematics, or a related field (required) 10+ years of experience building and deploying production-grade AI/ML systems Deep knowledge of machine learning, deep learning, and applied AI Experience across the full ML lifecycle: data curation, training, deployment, monitoring A track record of building things that ship—whether it’s recommendations, search, machine translation, or something equally complex Experience adapting or training foundation models (language or multimodal) for novel domains Bonus Points (or skills you’ll build here) You've built agents that can plan, reason, and use tools You know your way around cloud infrastructure (AWS, GCP, Azure) You’ve worked in a fast-moving startup or high-growth environment Additional Job details The base salary range for this posit

PythonSQLAWSAzure
SC
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$90K – $115K/yr

Quick readStrong listing-quality and freshness signals

Sigma is growing rapidly, and our Technical Support Engineering team is scaling alongside it to meet the needs of an expanding global user base. As a Technical Support Engineer at Sigma, you will be part of an award-winning team recognized with the 2024 Stevie Gold Award for Customer Service, helping customers solve technical, business, and data challenges using the Sigma platform. You'll work closely with Product, Engineering, and Go-to-Market teams to diagnose complex issues, drive solutions, and contribute to the continuous improvement of our product and support operations. Minimum Education Requirement This position requires a U.S. Bachelor's degree (or foreign equivalent) in Computer Science, Software Engineering, Information Systems, Data Science, or a closely related technical field. This requirement is a minimum and cannot be substituted by work experience alone. What You Will Be Doing You will work with Sigma's customers and the pre-sales team to assist with the diagnosis and resolution of complex technical issues. Working closely with the development team, you will develop best practices and tools for diagnosing issues and optimizing the service for performance. Collaborate with cross-functional groups — backend, frontend, DevOps, design, product, and the go-to-market teams to create a first-class experience for users of our product. Participate in quarterly projects and perform periodic on-call duties to improve automation and processes. Qualifications We Are Looking For 2+ years of experience in a customer-facing technical role (Technical Support, Solutions Engineering, or Software Engineering) at a cloud or SaaS provider. SQL proficiency — strong grasp of JOINs, Partitions, Window Functions, Aggregations, CTEs, and sub-queries. SQL query performance troubleshooting and query plan analysis. Proficient in data modeling concepts. Ability to chart data into logical visualizations. A proven track record of building trust with customers and brin

PythonSQLAWSGCP
SC
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$240K – $270K/yr

Quick readStrong listing-quality and freshness signals

About the Role Sigma is transforming how businesses run by delivering a high performance platform on the modern data architecture. Hence, we are growing the engineering team and looking for engineers who are excited to solve challenging problems, deliver impactful capabilities throughout our stack to build world-class technology. You will be part of a talented team of engineers with a shared mission to make data easily accessible for all users. What You Will Be Doing Solve challenging problems that arise in providing an interactive experience on data warehouses for data exploration and analysis Build with modern tools and languages like Rust, Go, GraphQL, Node, and Kubernetes Build backend distributed services, new algorithms and modern API to support a cloud application Triage product or system issues and debug/track/resolve by analyzing the sources of issues Design and implement new software features to support our fast growing user base Collaborate with peers and stakeholders through design and code reviews to ensure best practices amongst available technologies Qualifications We Need 5+ years industry experience building and maintaining high-quality software Experience building and deploying robust and secure web applications in a continuous deployment environment Desire to be a great teammate and have fun at work without compromising ownership towards your work Strong sense of craftsmanship, and a healthy academic curiosity to solve challenges at sigma Strong Computer Science fundamentals Qualifications We Want (also, skills you’ll learn!) Data driven aptitude and its application to solve distributed system problems Data model design, and API development experience SQL query optimization and database internals Administered cloud service infrastructure (GCP, AWS, Azure) Prior experience working at high growth company solving technical problems to enable continued success Additional Job details The base salary range for this position is $240k - $270

PythonSQLAWSAzure
SC
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$230K – $270K/yr

Quick readStrong listing-quality and freshness signals

Sigma is transforming how businesses run by delivering a high performance platform on the modern data architecture. As we grow the engineering team, we are looking for engineering leaders who want to build great products, devising product development, prioritization and execution strategy as well as developing a strong team providing career development, coaching, mentoring, performance evaluations, developing promotion cases, and other managerial responsibilities. About the role: We are looking for a self motivated, engineering leader eager to lead engineering teams with high performing engineers. You will need to be comfortable working in a fast-paced environment and support your teams to deliver incrementally against our roadmap. What you will be doing: Collaborate with cross-functional groups, executive team, field teams to devise business impact product strategy Enable the team to realize their potential and set them for achieving their career development goals Own execution and delivery of roadmaps, to help setup the business and your team for success Partner with the staffing team to recruit and build performing team Instill a strong sense of ownership and accountability within the team wherein members hold each other to a high bar Participate in discussions pertaining to the architecture and implementation techniques to represent, translate and optimize user directives into optimized queries You: Love working with world-class engineers, product managers, and architects to solve complex problems and enable business impact Have 5+ years of technical experience and 2+ years of people management experience Are opinionated and have great product sense make data driven decisions when unblocking the business Have hired, and developed high performing engineering teams Are curious, love to learn and to dig into new technologies to apply them when solving technical challenges Have demonstrated strong technical architecture and engineering skil

PythonSQLAIGo
SC
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$240K – $270K/yr

Quick readStrong listing-quality and freshness signals

About the Role At Sigma, we’re not just adding AI—we’re building the future of how people work with data. Our platform already lets users explore billions of rows of data in seconds with a spreadsheet-like interface, analyze and present their data in workbooks, and build data apps and workflows. Now we’re pushing further, applying AI to reshape how people build in Sigma, discover insights, and make smarter decisions—fast. That’s where you come in. As an AI/ML Engineer, you’ll join a growing team focused on building the AI foundation that will power Sigma for the future. Your work will become an integral part of the workflow for the thousands of enterprises that run on Sigma. What You’ll Do Partner with product, design, and engineering teams to identify high-impact AI/ML opportunities Prototype and productionize AI systems that feel intuitive but do a lot under the hood—recommendations, natural language interfaces, agentic workflows, and more Develop and scale AI/ML infrastructure that powers both internal tooling and customer-facing features Tackle novel UX problems at the intersection of AI, BI, and apps What You Bring Bachelor’s degree in Computer Science, Engineering, Mathematics, or a related field (required) 10+ years of experience building and deploying production-grade AI/ML systems Deep knowledge of machine learning, deep learning, and applied AI Experience across the full ML lifecycle: data curation, training, deployment, monitoring A track record of building things that ship—whether it’s recommendations, search, machine translation, or something equally complex Experience adapting or training foundation models (language or multimodal) for novel domains Bonus Points (or skills you’ll build here) You've built agents that can plan, reason, and use tools You know your way around cloud infrastructure (AWS, GCP, Azure) You’ve worked in a fast-moving startup or high-growth environment Additional Job details The base salary range for this posit

PythonSQLAWSAzure
SC
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$170K – $240K/yr

Quick readStrong listing-quality and freshness signals

Senior Software Engineer - Observability and Reliability About the Role We are growing the engineering team and looking for engineers who have the chops to build and deliver world-class technology. You will be part of a talented team of engineers with a shared mission to make data easily accessible. What You Will Be Doing Build observability tools and platforms, including: metrics, logging, distributed tracing, dashboarding, alerting, application performance management Build with modern tools and languages like Go, Open Telemetry and Kubernetes Participate in on-call rotation and ensure uptime of services Create runtime tools/processes that optimize cloud triaging and limit downtime Define best practices around making our systems and services measurable Collaborate with peers and stakeholders through design and code reviews to ensure best practices amongst available technologies. We expect successful candidates to be coding a majority of their time Qualifications We Need Strong Computer Science fundamentals 5+ years industry experience building and maintaining high-quality software, especially software other engineers use You apply a product mindset to infrastructure systems and feel accomplished enabling others Desire to be a great teammate and have fun at work Strong sense of craftsmanship, and a healthy academic curiosity Qualifications We Want (also, skills you’ll learn!) Experience building systems for data analytics Distributed systems monitoring and profiling skills Knowledge of cloud application security models Administered cloud service infrastructure (GCP, AWS, Azure) Startup experience Additional Job details Additional Job details The base salary range for this position is $170k - $240k annually. Compensation may vary outside of this range depending on a number of factors, including a candidate’s qualifications, skills, competencies and experience. Base pay is one part of the Total Package that is provided to compensate and recognize e

PythonSQLAWSAzure
SC
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$170K – $240K/yr

Quick readStrong listing-quality and freshness signals

About the Role Sigma is transforming how businesses run by delivering a high performance platform on the modern data architecture. Hence, we are growing the engineering team and looking for engineers who are excited to solve challenging problems, deliver impactful capabilities throughout our stack to build world-class technology. You will be part of a talented team of engineers with a shared mission to make data easily accessible for all users. What You Will Be Doing Solve challenging problems that arise in providing an interactive experience on data warehouses for data exploration and analysis Build with modern tools and languages like Rust, Go, GraphQL, Node, and Kubernetes Build backend distributed services, new algorithms and modern API to support a cloud application Triage product or system issues and debug/track/resolve by analyzing the sources of issues Design and implement new software features to support our fast growing user base Collaborate with peers and stakeholders through design and code reviews to ensure best practices amongst available technologies Qualifications We Need 5+ years industry experience building and maintaining high-quality software Experience building and deploying robust and secure web applications in a continuous deployment environment Desire to be a great teammate and have fun at work without compromising ownership towards your work Strong sense of craftsmanship, and a healthy academic curiosity to solve challenges at sigma Strong Computer Science fundamentals Qualifications We Want (also, skills you’ll learn!) Data driven aptitude and its application to solve distributed system problems Data model design, and API development experience SQL query optimization and database internals Administered cloud service infrastructure (GCP, AWS, Azure) Prior experience working at high growth company solving technical problems to enable continued success Additional Job details The base salary range for this position is $170k - $240

PythonSQLAWSAzure
SA
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $264.8K/yr

Quick readStrong listing-quality and freshness signals

Scale AI is the data foundation for AI, helping organizations build and deploy reliable production AI applications. We partner with leading enterprises and government organizations to accelerate their AI initiatives through our data annotation platform, generative AI solutions, and enterprise AI capabilities. About the General Agents Team The General Agents team, part of Scale’s Enterprise organization, builds robust general agents for customer use cases and applications. The team sits at the intersection of frontier agent development and real-world deployment, translating state-of-the-art reasoning and agentic capabilities into reliable, production-grade systems that drive real economic value. Our agents are scalable systems built around recurring enterprise problem domains, with a strong emphasis on generalization, extensibility, and deployment across many customers. About the Role As a Senior/Staff Machine Learning Engineer (MLE) on the General Agents team, you’ll play a critical role in designing, building, and deploying production-ready AI agents that solve high-impact enterprise problems. You will work across the full agent lifecycle—from model and system design to evaluation, deployment, and iteration—bridging cutting-edge agentic techniques with the constraints and requirements of real customer environments. You will: Design and implement end-to-end agent systems that combine LLM reasoning, tool use, memory, and control logic to solve recurring enterprise use cases. Build scalable, reliable agent architectures that can be deployed across many customers with varying data, tools, and constraints. Develop evaluation frameworks, datasets, environments, and metrics to measure agent performance, reliability, and business impact in production settings. Collaborate closely with product managers, customers, data annotators, and other engineering teams to translate enterprise requirements into robust agent designs. Productionize frontier agent techniques (e.g.,

PythonAWSRestMachine Learning
SA
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $216K/yr

Quick readStrong listing-quality and freshness signals

Software is eating the world, but AI is eating software. We live in unprecedented times – AI has the potential to exponentially augment human intelligence. Every person will have a personal tutor, coach, assistant, personal shopper, travel guide, and therapist throughout life. As the world adjusts to this new reality, leading platform companies are scrambling to build LLMs at billion scale, while large enterprises figure out how to add it to their products. To make them safe, aligned and actually useful, these models need human eval and reinforcement learning through human feedback (RLHF) during pre-training, fine-tuning, and production evaluations. This is the main innovation that’s enabled ChatGPT to get such a large headstart among competition. At Scale, our products include the Generative AI Data Engine, SGP, Donovan, and others that power the most advanced LLMs and generative models in the world through world-class RLHF, human data generation, model evaluation, safety, and alignment. The data we are producing is some of the most important work for how humanity will interact with AI. At the foundation of these products is the Identity Engineering team. In this role, you will help support the design and development of core software systems specifically focused on identity, access management, authorization, and authentication. You’ll also get widespread exposure to the forefront of the AI race as Scale sees it in enterprises, startups, governments, and large tech companies. You will: Drive the design, and implementation of our identity infrastructure to ensure secure authentication and authorization across enterprise systems. Build software for authentication mechanisms such as Single Sign-On (SSO), Multi-Factor Authentication (MFA), and federated identity solutions (SAML, OAuth, OpenID Connect). Build software for authorization mechanisms such as Relation-based access control (ReBAC), Attribute-based access control (ABAC), Role-based access cont

PythonJavaNode.jsAWS
DU
📍 San Francisco, Canada· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

About the Team DoorDash Labs is an independent team within DoorDash. We explore robotics and automation to transform last mile logistics in the long term. If you have a passion for applying robotics solutions in a service used by millions of people, then we want to talk to you! About the Role We are hiring a Software Integration Engineer for our Platform Integration team. This is a critical role with impact across the robot lifecycle, from manufacturing to daily operation. The Platform Integration team owns making sure the robot works as one cohesive system. The focus is on the interfaces between subsystems; this role in particular is focused on the software side handling interaction between: OS & software stack; firmware; networking; timing; and calibration. In this role, you will work cross functionally with our electrical, hardware, firmware, and autonomy engineers to support new functionality both in both hardware and software. This includes creating provisioning tools, functional tests, and supporting integration into the autonomy software stack. You will report to the Autonomy Platform Lead on our Autonomy Platform Team at DoorDash Labs. We expect this role to be hybrid with some time in-office and some time remote. You’re excited about this opportunity because you will… Play an integral role on a small and focused team. Lead system-level debug when an issue crosses subsystem boundaries or no single team can isolate it. Support early integration of new sensor and software component designs by identifying interface requirements, risks, dependencies and required checks. Design and maintain integration tests, test setups, and procedures to ensure subsystems, once combined, satisfy requirements and design intent. Build and maintain the mission-readiness checks used before manufacturing signoff, validation, field testing, or mission use for different robot platforms. Create the tools, checks, and debug guidance that Manufacturing Integration, Validation,

PythonAWSGitRest
DU
📍 San Francisco, Canada· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

About the Team DoorDash’s GenAI Platform team sits within Machine Learning Platform and builds the shared infrastructure that helps DoorDash, Wolt, and Deliveroo teams safely bring GenAI-powered products, agents, automation, and personalization to production. Our mission is to increase the velocity of business impact from GenAI. A central pillar of that work is running frontier open-weight LLMs and VLMs (such as GLM, Qwen, Kimi, and DeepSeek) ourselves — real-time GPU serving, high-throughput batch inference, and fine-tuning on autoscaling GPUs — delivering large cost and latency wins (for example, a billion embeddings produced roughly 20× cheaper and visual models served roughly 72% cheaper). We also own core platform surfaces including the LLM Gateway, Agent Gateway, evals infrastructure, guardrails, and cost attribution. About the Role You will join a small, high-leverage team building production infrastructure for Generative AI at DoorDash, leading the design and architecture of our open-weights model platform spanning inference and fine-tuning: real-time GPU serving, high-throughput batch inference, and model fine-tuning. You’ll set technical direction across model serving and inference engines, fine-tuning and training pipelines, GPU autoscaling and utilization, batch pipelines, backend services, and observability, and mentor engineers as you go. This role is ideal for a senior engineer who enjoys owning ambiguous, high-impact systems and pushing the cost/performance frontier of GPU inference and fine-tuning in a fast-moving technical area where product needs, model capabilities, vendor ecosystems, and cost/performance tradeoffs are evolving quickly. You’re excited about this opportunity because you will… Lead the design of infrastructure that helps DoorDash teams move GenAI ideas from prototype to production, increasing the velocity of business impact from AI across the company. Own and evolve our open-weights serving stack — real-time GPU endpoints, high-thr

PythonAWSGCPKubernetes
G
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$180K – $205K/yr

Quick readStrong listing-quality and freshness signals

About Glean: Glean is the Work AI platform that helps everyone work smarter with AI. What began as the industry’s most advanced enterprise search has evolved into a full-scale Work AI ecosystem, powering intelligent Search, an AI Assistant, and scalable AI agents on one secure, open platform. With over 100 enterprise SaaS connectors, flexible LLM choice, and robust APIs, Glean gives organizations the infrastructure to govern, scale, and customize AI across their entire business - without vendor lock-in or costly implementation cycles. At its core, Glean is redefining how enterprises find, use, and act on knowledge. Its Enterprise Graph and Personal Knowledge Graph map the relationships between people, content, and activity, delivering deeply personalized, context-aware responses for every employee. This foundation powers Glean’s agentic capabilities - AI agents that automate real work across teams by accessing the industry’s broadest range of data: enterprise and world, structured and unstructured, historical and real-time. The result: measurable business impact through faster onboarding, hours of productivity gained each week, and smarter, safer decisions at every level. Recognized by Fast Company as one of the World’s Most Innovative Companies (Top 10, 2025), by CNBC’s Disruptor 50, Bloomberg’s AI Startups to Watch (2026), Forbes AI 50, and Gartner’s Tech Innovators in Agentic AI, Glean continues to accelerate its global impact. With customers across 50+ industries and 1,000+ employees in more than 25 countries, we’re helping the world’s largest organizations make every employee AI-fluent, and turning the superintelligent enterprise from concept into reality. If you’re excited to shape how the world works, you’ll help build systems used daily across Microsoft Teams, Zoom, ServiceNow, Zendesk, GitHub, and many more - deeply embedded where people get things done. You’ll ship agentic capabilities on an open, extensible stack, with the craf

PythonJavaAWSGit
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