Laboratory Director

As the Associate/Laboratory Director, you have clinical oversight of Natera’s laboratory testing. You ensure that testing is properly performed, and applicable regulatory standards are met. You are responsible for ensuring that the laboratory implements testing while consistently providing accurate and reliable patient test results. PRIMARY RESPONSIBILITIES: Review, approve, and sign-out reports for a variety of clinical molecular/cytogenetic and/or oncologic results, including NIPT, carrier screening, PGD/PGS, products of conception and rare disease testing on platforms including SNP array analysis, NGS, and other methodologies. Oversee the review of genetic and CNV variant data: interpret NGS and microarray results in the context of medical literature, online variant databases and other references along with relevant patient demographic data. Provide clinical and technical support for genetic counselors and other laboratory personnel. Set standards for laboratory testing and acceptable levels of analytic performance and ensure these are maintained. Analyze lab data, contribute to or write publications for high-quality scientific journals. May serve as Technical Supervisor. The Technical Supervisor is responsible for ensuring: appropriate test method selection; adequate method verification to determine the accuracy and precision of the test; enrollment of the laboratory in a CMS-approved proficiency testing (PT) program for the test performed; PT samples are tested in accordance with the CLIA requirements; PT results are returned within the time frames established by the PT program; PT reports are reviewed by the appropriate staff; corrective action plans are followed when PT results are found to be unacceptable or unsatisfactory; quality assessment and quality control programs are established and maintained; acceptable analytical test performance is established and maintained for each test system; remedial actions are taken and documented when signific

As the Associate/Laboratory Director, Oncology and one of our Laboratory Directors, you have clinical oversight of Natera’s laboratory testing. You ensure that testing is properly performed, and applicable regulatory standards are met. You are responsible for ensuring that the laboratory implements testing while consistently providing accurate and reliable patient test results. PRIMARY RESPONSIBILITIES: Review, approve, and sign-out reports for a variety of clinical molecular/cytogenetic and/or oncologic results, including the Signatera MRD assay and other Next Generation Sequencing based assays. Oversee the review of genetic and CNV variant data: interpret NGS results in the context of medical literature, online variant databases and other references along with relevant patient demographic data. Provide clinical and technical support for genetic counselors and other laboratory personnel. Set standards for laboratory testing and acceptable levels of analytic performance and ensure these are maintained. Analyze lab data, contribute to or write publications for high-quality scientific journals. May serve as Technical Supervisor. The Technical Supervisor is responsible for ensuring: appropriate test method selection; adequate method verification to determine the accuracy and precision of the test; enrollment of the laboratory in a CMS-approved proficiency testing (PT) program for the test performed; PT samples are tested in accordance with the CLIA requirements; PT results are returned within the time frames established by the PT program; PT reports are reviewed by the appropriate staff; corrective action plans are followed when PT results are found to be unacceptable or unsatisfactory; quality assessment and quality control programs are established and maintained; acceptable analytical test performance is established and maintained for each test system; remedial actions are taken and documented when significant deviations from the laboratory’s established

This is an exciting opportunity to lead and grow the Data Science and Bioinformatics function supporting Natera's Women's Health and Organ Health product portfolios. In this role, you will build the bioinformatics capability within the Data Science development team, establish scalable AWS cloud infrastructure, and ensure the quality and reproducibility of the genomic algorithms powering our clinical products. PRIMARY RESPONSIBILITIES: Strategy and Vision Build and define the Bioinformatics function within the Data Science development team, identify technical tooling gaps, and execute a roadmap to advance genomics-based algorithm development. Establish and enforce pipeline and algorithm quality standards, including review processes, validation frameworks, and documentation practices Infrastructure and Automation Own and architect scalable AWS-based data science and bioinformatics infrastructure, ensuring quality, reproducibility, and reliable deployment of Next-Generation Sequencing (NGS) algorithms. Implement MLOps tooling and automated validation frameworks to support reliable algorithm deployment into clinical production. Cross-Functional Collaboration Partner with Research, Product Development, Laboratory Operations, Engineering, and Quality teams to implement stable, scalable pipelines and support successful productization Team Leadership Lead, mentor and hire a high-performing team of bioinformaticians and data scientists, establishing technical quality standards and clear operational ownership. Build technical depth within the team to support expanding product roadmaps across Women's Health and Organ Health. QUALIFICATIONS: Master of Science or Ph.D. in a quantitative technical discipline (Biostatistics, Bioinformatics, Computer Science, Physics, Applied Mathematics, or equivalent). Minimum of 10 years of experience in Data Science or Bioinformatics, with at least 5 years of direct people management experience leading technical teams. Hands-on experience archi

The Laboratory Waste Technician is an entry-level position within the Environmental Health and Safety (EHS) department, responsible for the safe collection, handling, and management of laboratory waste streams in compliance with all applicable federal, state, and local regulations. This role supports day-to-day waste management operations across laboratory and research spaces, ensuring proper accumulation, labeling, packaging, and disposition of chemical, biological, and mixed waste. Reporting directly to the EHS Supervisor, you will work collaboratively with laboratory staff to maintain compliant and organized waste accumulation areas. You will own hazardous waste operations on the floor, gaining immediate, hands-on experience driving compliance with RCRA and DOT regulations in a fast-paced lab environment. Core Responsibilities Collect, segregate, label, and transport chemical, biological, and mixed waste from laboratory accumulation areas in accordance with RCRA satellite and central accumulation area requirements. Monitor waste accumulation start dates, container integrity, and labeling compliance throughout laboratory and research spaces to ensure regulatory deadlines are met. Move and manage biohazardous waste, including regulated medical waste and sharps, in compliance with applicable biosafety and institutional guidelines. Support hazardous waste shipment preparation in accordance with DOT regulations, including proper packaging, labeling, and marking of waste containers prior to off-site pickup. Keep lab operations moving quickly and without disruption by anticipating supply needs and executing waste pickups flawlessly. Partner with the EHS Supervisor to drive regulatory compliance, taking active ownership of recordkeeping, waste manifests, and lab inspections. Step in to resolve operational bottlenecks as they arise. Qualifications High school diploma or GED required; Associate’s degree or coursework in Environmental Science, Biology, Chemistry, or

POSITION SUMMARY: Join Natera’s Oncology Research Use Only (RUO) team as a Supervisor for the Signatera Plasma Team. You will direct laboratory staff executing cell-free DNA (cfDNA) extraction, library preparation, and Next-Generation Sequencing (NGS) workflows to advance our personalized Minimal Residual Disease (MRD) assays. Every sample represents a real person, and you will ensure that all lab processes operate with the pace and precision required to support our clinical pipeline. PRIMARY RESPONSIBILITIES: Oversee the daily scheduling of employees executing DNA extractions, library preparation, Nucleic Acid Quality Control (QC), and NGS workflows Conduct regular 1:1 meetings to deliver unvarnished, data-backed performance evaluations and guide career development Take ownership of daily lab operations by directly executing sample processing alongside the team to maintain throughput Serve as the primary technical point of contact, using data to guide team members on data interpretation, next steps, and troubleshooting Execute process development and method/instrument testing to increase operational precision and scale Use data to identify lab process deviations, root-cause the underlying issues, and document findings via nonconformance reports to drive corrective action Draft, generate, and rigorously review Standard Operating Procedures (SOPs) and work instructions Maintain precise records of lab work using Google Sheets, Microsoft Excel, and internal Laboratory Information Management Systems (LIMS) Ensure accurate, ethical, and appropriate management of samples in strict compliance with all applicable federal regulations Think team by partnering directly with Oncology RUO peer groups to eliminate bottlenecks and optimize sample processing without needing translation layers Present data-backed summaries on team activities, project milestones, and timeline adherence Adapt to evolving science and operational needs, taking ownership of tasks that move th

POSITION SUMMARY: Join Natera’s Oncology Research Use Only (RUO) team as the Laboratory Manager . You will take ownership of the physical operations, asset management, and Environmental Health and Safety (EH&S) compliance for a high-throughput Next-Generation Sequencing (NGS) research laboratory. This environment supports internal and externally contracted research studies rather than clinical diagnostic reporting. You will operate with pace and rigor, using data to anticipate bottlenecks and treating lab compliance as the foundation of execution. PRIMARY RESPONSIBILITIES: Lab Organization & Cleanliness Maintain a clean, safe, and well-organized laboratory that meets institutional and company standards Establish and enforce workspace organization standards, including bench layouts, labeling conventions, shared-equipment zones, and waste segregation Own housekeeping schedules, decontamination routines, and general lab organization, coordinating cleaning and biohazard or chemical waste pickup Ensure adequate stocking and organization of consumables at the point of use Serve as the point of contact for lab safety, ensuring Personal Protective Equipment (PPE) availability, spill readiness, and adherence to EH&S requirements Cross-Team Coordination & Equipment Think team by partnering directly with Facilities, Engineering/Instrumentation, EH&S, Procurement, and IT to drive lab operations without needing translation layers Coordinate preventive maintenance, calibration, service visits, and repair of major instrumentation (e.g., NGS sequencers, liquid handlers, qPCR/dPCR systems, centrifuges, thermal cyclers), minimizing downtime Manage vendor and service-provider relationships, including scheduling, tracking service tickets, and escalating unresolved issues based on data Own end-to-end inventory management, tracking reorder points, purchasing requests, receiving, and stock rotation for reagents, consumables, and controls Maintenance Logs & Protocol