Principal Hardware Design Engineer (Engineering Manager)

Job Title Principal Electrical Engineer- Medical Device Job Description As a Principal Electrical Engineer, you will be part of the multidisciplinary IntraSight Hardware Team, contributing to innovative imaging clinical solutions. You will serve as the key technical interface between Philips and external suppliers, design partners, and contract manufacturers for PCBA development, ensuring high-quality, reliable, and cost-effective electronic designs that meet performance, safety, quality, and regulatory requirements. Your role Serve as the primary electrical engineering interface to suppliers, design partners, and contract manufacturers, providing technical leadership for PCBA design, development, prototyping, and industrialization. Drive alignment on electrical requirements, schematics, PCB layout, architecture, acceptance criteria, timelines, cost, and quality. Lead supplier selection, technical evaluations, design reviews, and issue resolution in partnership with sourcing, procurement, and cross-functional engineering teams. Review and approve schematics, PCB layouts, and design documentation to ensure alignment with Philips standards and system architecture. Drive design for manufacturability (DFM), design for testability (DFT), design for cost (DFC), and component selection strategies while considering availability, lifecycle, obsolescence, and overall product cost. Manage supplier change requests and mitigate component and PCBA lifecycle risks. Oversee PCBA verification and validation, including functional, signal integrity, power integrity, electrical safety, and EMC testing, ensuring compliance with applicable medical device standards such as IEC 60601-1 and IEC 60601-1-2. Partner with quality and regulatory teams to ensure suppliers meet required quality systems, documentation, and regulatory expectati

About Tr1X Tr1X is a clinical-stage biotechnology company developing engineered Tr1 cell therapies to restore immune balance in autoimmune and inflammatory diseases. Leveraging the unique biology of Tr1 cells, the company is advancing a pipeline of off-the-shelf allogeneic and in vivo CAR-Tr1 therapies designed to deliver targeted immunoregulation and address diseases driven by immune dysfunction, including transplant-related complications. Founded by pioneers in the discovery of Tr1 cells, Tr1X, Inc. is focused on developing durable, potentially curative therapies for conditions with high unmet need. For more information, visit www.tr1x.bio. Position Summary The Principal Scientist, LNP Platform & Process Development (Scientist) is an experienced hands-on, lab-based, individual contributor that leads the design, development, and optimization of lipid nanoparticle (LNP) formulation and process development efforts supporting the Tr1X in vivo CAR-Treg platform. This individual plays a central role in developing and advancing the targeted lipid nanoparticle (tLNP) delivery systems from early research optimization through scalable, IND-enabling development. This is a high-impact, foundational role within the company. The Scientist helps design and implement the LNP backbone of the platform and influence both short-term program execution and long-term manufacturability strategy. The Scientist brings deep hands-on expertise in LNP formulation and process development, strong analytical rigor, and the ability to thrive in a fast-paced startup environment. Key Responsibilities Lead the design, development, and optimization of LNP formulations for mRNA delivery, including targeted LNP systems incorporating conjugated or functionalized lipids. Evaluate lipid composition, formulation parameters, and mixing conditions to optimize particle size, polydispersity, encapsulation efficiency, surface functionalization, stability, release characteristics, and biologica

Systems Technology Inc. (STI) is a private, employee-owned company (ESOP) that provides engineering consulting and product development with a focus on safety. We are a small company that enjoys many of the perks of start-ups, but we have been in business for over sixty years and have an aggressive growth plan. Being part of STI means being a key contributor in the company while working with a team that spans the range of experience from recent graduates to 20+ year tenure. At STI, we look for business partners who want to be part of something special and contribute to a culture built on transparency, friendliness, innovation, ownership and accountability. If you are of a like mind and enthusiastic about solving challenging, real world, relevant problems, we would love to hear from you. As a 100% employee-owned company, STI understands that employees' individual and collective hard work and dedication will lead directly to the success of the company in the long term. An Employee Stock Ownership Plan (ESOP) gives employees an ownership interest in the company that employs them. What You’ll Do: The Electrical Engineer designs, develops, and validates embedded electronics hardware for aerospace, defense, and advanced autonomy applications. This role spans the full hardware development lifecycle — from requirements capture and schematic design through PCB layout, board bring-up, and fielded system support. You’ll work closely with software and systems engineers, contribute to technical documentation and reporting, and grow into broader program ownership over time. Reports to a Principal Engineer or Engineering Manager. Design complex multilayer PCB assemblies for embedded systems used in aerospace, UAS, and defense applications Develop schematics and manage PCB layout using KiCad, Altium, or similar EDA tools Select and integrate sensors including IMUs, magnetometers, pressure sensors, GNSS receivers, and ADCs Design power supply circuitry including switching regulators

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. Roblox's Object Store team is building the in-house, multi-tenant object storage platform that underpins every large-object workload at Roblox — assets, media, analytics, backups, and machine learning datasets — at exabyte scale, trillions of objects, and terabytes per second of throughput. We build and run it ourselves on bare metal in our own data centers, replacing cloud object storage with a platform we control end to end — down to the hardware. As a principal engineer on the Object Store team, you will shape the architecture, build and launch the capabilities that keep this platform durable, fast, and efficient at global scale, and set the technical direction for where it goes next. You will report to the Engineering Manager for Storage. You will: Design and build the object store — S3-compatible gateway, metadata and indexing, data placement and tiering, multi-tenancy and isolation. Own the technical strategy : multi-year architecture, build-vs-buy calls, and the migration off cloud object storage. Evolve the control plane for elastic scaling, autonomous healing, self-service provisioning, and zero-downtime tenant moves. Run the bare-metal fleet at scale — cluster lifecycle, upgrades,

What you’ll do Act as the in-house electrical lead for Midjourney Medical: own the electrical architecture of the scanner and the technical direction for all board-level design. Own complex board design end-to-end: architecture, schematic capture, layout (high-speed digital, analog/mixed-signal, power), DFM/DFT, fabrication and assembly vendor management, bring-up, and revision control. Write firmware for embedded targets (MCU/SoC): drivers, real-time control loops, safety-relevant logic, bootloaders, and field update paths. Audit and update HDL (FPGA) code for high-throughput data acquisition, timing/synchronization, triggering, and pre-processing of ultrasound and sensor data streams. Define electrical interfaces and data contracts with software, recon/ML and mechanical teams: timing budgets, clocking/sync, signal integrity, connectors/harnessing, and failure modes. Establish electrical engineering rigor: design reviews, schematic/layout review checklists, bring-up procedures, test fixtures, and documentation suitable for a regulated medical device program (DHF, traceability, change control). Mentor and grow the electrical function; select and manage external design partners where leverage is high. What we’re looking for Deep experience designing complex boards from blank page to stable revision, including high-speed digital and analog/mixed-signal domains. Strong schematic and layout skills (Altium/KiCad or equivalent) with real signal integrity, power integrity, grounding, and EMI/EMC instincts. Solid embedded firmware background in C/C++ (and Python for tooling): peripherals, DMA, interrupts, real-time constraints, and debugging on hardware. Practical HDL experience (VHDL/Verilog/SystemVerilog) for data acquisition, timing, and streaming interfaces. Track record of owning bring-up and debug on real hardware: scopes, logic analyzers, and disciplined root-cause analysis. Technical leadership: clear trade-offs, strong written documentation, and the ability to set

This is where your work makes a difference. At Baxter, we believe every person—regardless of who they are or where they are from—deserves a chance to live a healthy life. It was our founding belief in 1931 and continues to be our guiding principle. We are redefining healthcare delivery to make a greater impact today, tomorrow, and beyond. Our Baxter colleagues are united by our Mission to Save and Sustain Lives. Together, our community is driven by a culture of courage, trust, and collaboration. Every individual is empowered to take ownership and make a meaningful impact. We strive for efficient and effective operations, and we hold each other accountable for delivering exceptional results. Here, you will find more than just a job—you will find purpose and pride. Your role at Baxter The Principal Systems Engineer will serve as a Product Design Owner (PDO) responsible for technical owner for the design, risk and integration of infusion pump systems and/or projects, which combine electro-mechanical hardware, embedded software, and user interface components, as well as the interface with other related EM and/or digital products. This role drives operational excellence and predictable, consistent execution in our products, and design and risk integrity and may serve as Risk Owner on some projects. The engineer is accountable for product safety, performance, reliability, usability and regulatory compliance, as well as risk. The PDO drives design decisions, manages design control activities, may be accountable for a product risk file, and collaborates across engineering disciplines and cross-functions to deliver robust, reliable, safe and innovative infusion therapy solutions. What you will be doing: Leads interdisciplinary design and development of medical products in compliance with FDA, EU MDR,