Research Scientist, Life Sciences (Computational)

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. About the team Anthropic's Life Sciences team is building a world-class research group focused on making fundamental biological discoveries. The team combines cutting-edge AI with hands-on biological research, positioning Anthropic at the forefront of AI-accelerated scientific discovery. About the role We're seeking an exceptional Research Scientist to join the team. As a founding member of Life Sciences, you'll work in a high-impact group that operates at the intersection of computational and experimental biology. You'll help establish Anthropic as a leader in biology research while developing product intuition through direct engagement with the challenges and opportunities of laboratory science. Key responsibilities Design, execute, and iterate on the experimental programs at the core of the team's research: molecular biology, biochemistry, protein and nucleic acid characterization, high-throughput functional screens, and the assay development that makes new questions answerable Partner directly with computational biologists to design experiments that produce high-quality, analysis-ready data, and feed results back fast enough to immediately inform the next round of analysis Generate and prioritize hypotheses by combining your experimental judgment with the literature, curated biological knowledge bases, and the team's computational predictions Use Claude and our internal agent frameworks heavily in your own work — for experimental planning, protocol development, and data interpretation — and feed what you learn back to the model-improvement and product teams as evaluations, datasets, and concrete failure cases Minimum qualification

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. We're seeking an exceptional Research Scientist to join our Life Sciences team at Anthropic. Our team is building a world-class research group focused on making Claude a superhuman life sciences research assistant. This role sits at the intersection of machine learning, software engineering, and biology — you'll directly improve model capabilities on scientific tasks through post-training, evaluation design, and RL environment development. As a core member of our Life Sciences team, you'll work in a high-impact team that translates deep biological domain knowledge into model training objectives, benchmarks, and agentic workflows. You'll help establish Anthropic as a leader in AI-accelerated biology while shaping how frontier models reason about and execute computational biology tasks. This role offers a unique opportunity to shape how frontier AI models learn to do biology. You'll work alongside some of the world's best AI researchers while tackling problems that matter for human health and scientific understanding. If you're excited about turning your computational biology expertise into model capabilities, we want to hear from you. Key Responsibilities Build and ship agentic tools and integrations that let Claude execute real life science workflows — bioinformatics pipelines, database queries, analysis notebooks, literature review Design and build evaluation benchmarks that measure model capabilities on biology tasks — figure interpretation, bioinformatics, protocol reasoning, literature synthesis Work closely with product and design teams to scope, prototype, and ship features for life sciences users Partner with external biotech,

About the team Life sciences is one of the clearest areas where advances in intelligence can meaningfully benefit the world at large. The OpenAI Life Sciences team works at the intersection of advancing frontier life sciences model capabilities and building products to help scientists accelerate their research and leverage the full potential of AI for scientific work. We’re building platforms that connect model intelligence with practical scientific workflows. Our work covers workflows from next-gen sequencing analysis to designing new drugs, helping scientists run computational workloads as well as access laboratory services. By making these capabilities more accessible and useful, we aim to improve early discovery and support downstream progress in drug development. About the role We’re looking for experienced full-stack product engineers with strong backend skills to join our growing Life Sciences team. This is an individual contributor role with substantial ownership. You’ll help define products, design systems, and ship experiences that connect scientists with AI capabilities and laboratory workflows. You’ll work across the stack, partnering with researchers, scientists, and infrastructure engineers to turn complex needs into reliable, intuitive products. We value strong engineering fundamentals, product judgment, and experience shipping to large user bases. Life sciences experience is helpful, but you don’t need a scientific background to make a meaningful contribution. In this role, you will Design backend services, APIs, and integrations that connect users with models, scientific tools, and laboratory services. Create intuitive interfaces that help scientists navigate complex workflows. Own projects from problem definition and technical design through launch, operation, and iteration. Work with scientific and research partners to identify user needs and prioritize valuable product improvements. Partner with dedicated infrastructure engineers on performance,

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. About the role Anthropic's Life Sciences team is building a research group focused on biological discoveries by combining AI with hands-on biological research. We're seeking research scientists with deep medicinal chemistry expertise to join the team. Our goal is to speed up progress in the life sciences by an order of magnitude, and this role puts that mission into practice. You'll be an expert medicinal chemist with hands-on experience designing, synthesizing, purifying, and characterizing small molecules. Above all, you'll close the loop between AI-generated hypotheses and experimental data to share with the community. Working alongside AI researchers and engineers, you'll drive experimental programs end to end and pressure-test AI-designed molecules and AI-proposed synthetic routes against real chemistry. This role is fully on-site in the San Francisco Bay Area. Key responsibilities Design multi-step synthetic routes for small molecules and oversee their execution end to end, including route selection, reaction optimization, purification strategy, and interpretation of full characterization data (NMR, LC-MS, HPLC) Coordinate synthesis and biological evaluation with external contract research organizations and academic partners Evaluate AI-designed molecules and AI-proposed synthetic routes, drive them to experimental readout, and feed results back to research teams Apply medicinal chemistry principles, including SAR analysis and physicochemical property optimization, to compound design and prioritization Ensure experimental data across programs is high quality and well documented, including procedures, spectra, and failure modes C

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. About the role We are looking for research engineers to build the safety and oversight mechanisms that govern how our models handle biological knowledge. As a bio safety researcher, you will spend your time: designing and running capability evaluations against frontier models, generating and curating training data for our safety classifiers, training and iterating on those classifiers alongside our ML engineers, and measuring how they hold up against adversarial pressure in production traffic. This work sits at the intersection of applied ML and biosecurity. You will help define what responsible AI safety looks like in the biological domain, translating threat models into evals, datasets, and deployed systems. The core technical tension you will own is precision: safeguards need to be robust against sophisticated actors while staying out of the way of the far larger population of legitimate researchers using Claude to accelerate life sciences work. Getting that tradeoff right is an empirical problem, and you will be the person measuring it. You do not need to be an ML researcher today. We are looking for strong scientific programmers with real depth in modern biology who want to bring that depth to bear on model evaluation and classifier development. Key responsibilities Design, build, and run capability evaluations to assess what new models can do in the biological domain, and turn results into concrete deployment recommendations Develop training and evaluation datasets for our safety classifiers, working with internal and external threat modeling experts to ground them in realistic risk Train, tune, and iterate on safety classifiers

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. About the role Anthropic's Safeguards organization builds the policies, evaluations, and enforcement systems that keep our models from contributing to catastrophic harm. We are hiring a manager to lead the research engineering team responsible for biological safety: the evaluations, datasets, and classifiers that govern how our models handle biological knowledge. You will lead a team of research scientists and engineers who design and run capability evaluations against frontier models, curate training data for our safety classifiers, train and iterate on those classifiers alongside our ML engineers, and measure how they hold up against adversarial pressure in production traffic. You will set the technical direction for that work, decide where the team invests, and own the results. This is a hands-on management role. Most of your time goes to growing and directing the team, but you will keep enough technical depth to review an eval design, interrogate a classifier's failure modes, and represent the work credibly to Research, Product, and Policy partners. The core tension your team owns is precision: safeguards need to be robust against sophisticated actors while staying out of the way of the far larger population of legitimate researchers using Claude to accelerate life sciences work. Getting that tradeoff right is an empirical problem, and your team is the one measuring it. Key responsibilities Manage, coach, and grow a team of research scientists and engineers working on biological safety evaluations and classifiers, including hiring, onboarding, performance, and career development Set the technical direction and roadmap for the biol