Scientist R&D

POSITION SUMMARY: Natera is a global leader in cell-free DNA testing. We measure fetal, tumor, or donor cfDNA at the molecular level to help inform personalized health care decisions with a non-invasive test. The Natera R&D Department is looking for a highly motivated Senior Scientist to join the rapidly growing assay development team to help build the future of Natera. In this position, you will be an integral part of high-performing teams across functions to develop laboratory tests that positively impact the business and our patients. A successful candidate will have a deep understanding of molecular biology, strong scientific curiosity and high level of expertise of developing cfDNA assays through product development cycles. You will lead and support dedicated junior scientists and laboratory technicians to plan, execute and manage scientific studies under design control in a regulated environment to help improve and expand Natera's state-of-the-art product portfolios. PRIMARY RESPONSIBILITIES: Lead technical projects and associated timelines and deliverables as a subject matter expert and represent the assay development group in cross-functional project teams. Drive the planning, design, execution, and reporting of feasibility, development, verification and validation studies under the design control quality system. Collaborate closely with research scientists, automation engineers, biostatisticians and data scientists within a dynamic R&D team to develop new and innovative molecular assays. Communicate and document experimental data, scientific findings, and recommendations to R&D and other functions including Lab Operations, Scientific Affairs, Product Management, Quality, and Regulatory groups. May manage Research Associates. QUALIFICATIONS: Typically requires a university degree and a minimum of 8+ years of related experience or a MS degree and 6 years of related experience or a PhD and 4 years of related experience Knowledge of high throughput

POSITION SUMMARY: Natera is a global leader in cell-free DNA testing. We measure fetal, tumor, or donor cfDNA at the molecular level to help inform personalized health care decisions with a non-invasive test. The Natera R&D Department is looking for a highly motivated Staff Scientist to join the rapidly growing assay development team to help build the future of Natera. In this position, you will be an integral part of high-performing teams across functions to develop laboratory tests that positively impact the business and our patients. A successful candidate will have a deep understanding of molecular biology, strong scientific curiosity and high level of expertise of developing cfDNA assays through product development cycles. You will lead and support dedicated junior scientists and laboratory technicians to plan, execute and manage scientific studies under design control in a regulated environment to help improve and expand Natera's state-of-the-art product portfolios. PRIMARY RESPONSIBILITIES: Lead technical projects and associated timelines and deliverables as a subject matter expert and represent the assay development group in cross-functional project teams. Drive the planning, design, execution, and reporting of feasibility, development, verification and validation studies under the design control quality system. Collaborate closely with research scientists, automation engineers, biostatisticians and data scientists within a dynamic R&D team to develop new and innovative molecular assays. Communicate and document experimental data, scientific findings, and recommendations to R&D and other functions including Lab Operations, Scientific Affairs, Product Management, Quality, and Regulatory groups. May manage Scientists or Research Associates. QUALIFICATIONS: BS, MS. or PhD Degree in genetics, molecular biology, biochemistry or a closely related field. PhD with a minimum of 6 years relevant experience, or a MS degree and mini

Position Summary This is a full-time, contract hybrid position in South San Francisco, CA. The Contract Design Control Scientist supports the Platform department by owning and improving design controlled documentation across the product development lifecycle. This role bridges R&D science and regulatory compliance; translating laboratory processes, study data, and software workflows into traceable, audit-ready deliverables. The ideal candidate combines a strong scientific foundation with the ability to navigate regulated environments, engage cross-functional stakeholders, and communicate complex technical concepts to audiences ranging from R&D scientists to clinical professionals. Primary Responsibilities Author and maintain design controlled documentation in compliance with FDA QMSR, 21 CFR Part 11, GCP, CAP/CLIA, HIPAA, IVDR, and GDPR. Translate laboratory processes, study plans, and analytical data into traceable, compliant deliverables (e.g., development reports, verification/validation protocols, specifications). Establish and maintain traceability across project documentation, linking requirements to design outputs and verification evidence. Review development reports, team resources, and software scripts to extract and synthesize information for controlled documents. Create onboarding and training documentation for R&D and CLIA team members, including training plans and departmental practice descriptions. Manage documentation filing, version control, and change-control workflows within quality management systems. Identify opportunities to improve documentation processes, templates, and deliverable quality. Perform other duties as assigned. Qualifications BS or higher in a scientific discipline (molecular biology, biochemistry, genomics, or related field) or equivalent industry experience. 5+ years of experience producing controlled documentation in the medical device, IVD, or life science industry. Demonstrated experience working in

About the role Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who are passionate about delivering the possible to patients, and who lead with the desire to work on novel ideas. As a Principal Scientist, Potency, you will report to the Sr. Director, Head of Molecular and Potency Method Development. You will either lead or support the development and implementation of potency, immunoassay, and other cell-based methods for Sana’s cell therapy products, and support method transfer and qualification to enable GMP testing. This role is onsite in South San Francisco, CA. What you’ll do Act as a key contributor in developing and qualifying pivotal stage potency, immunoassay, and other cell-based methods to support the characterization, process development, release testing, and stability testing of cell therapy products Follow ICH and internal Method Development Guidance Document to develop robust analytical methods for characterizing intermediates, drug substances/products and measuring residual impurities Develop product characterization strategies and methodologies to advance Sana’s pipeline Develop and execute methods to implement control strategies for gene and cell therapy products Create detailed documentation of experimental procedures and results in the electronic laboratory notebook and complete the review and approval of notebook entries per established policy Present results at group meetings and communicate effectively with a broad audience with a range of technical, analytical, and biological expertise Serve as a subject matter expert on potency, immunoassay, and other cell-based methods Draft, review, and/or approve technical documents (e.g., Test Methods, SOPs, Development Reports, and Technical Reports, and comprehensive study plans) Perform calibration, maintenance, troubleshooting, and qualification of instruments and reagents Maintain inventory of reagents and improve

POSITION SUMMARY Natera is seeking a highly motivated Scientist, R&D – Immunohistochemistry (IHC) & Histology to join the Oncology Product Development team. This role will focus on the development, optimization, verification, and validation of IHC and tissue-based workflows supporting oncology products and clinical assay development. The ideal candidate will have strong hands-on experience in IHC assay development and optimization, supported by a solid foundation in histology and FFPE tissue workflows. Experience with automated IHC/ISH staining platforms, particularly the Roche BenchMark ULTRA IHC/ISH System, is highly desirable. Experience with NGS and molecular biology workflows is an additional plus. PRIMARY RESPONSIBILITIES Design and execute development, optimization, verification, and validation studies for IHC, histology, and tissue-based workflows. Develop and optimize IHC assays, including antibody selection and titration, antigen retrieval, staining conditions, controls, and assay performance assessment. Evaluate and optimize histology and pre-analytical variables, including tissue fixation, FFPE processing, embedding, sectioning, H&E staining, and slide preparation. Develop and troubleshoot workflows on automated IHC/ISH staining platforms and investigate staining artifacts, reagent performance, tissue quality, and assay variability. Plan and execute moderate- to high-complexity experiments; analyze and interpret results using tools such as Excel, JMP, and image-analysis approaches. Collaborate with Pathology, Clinical Laboratory Operations, Quality, Automation, and other cross-functional teams to transfer R&D methods into robust clinical laboratory workflows. Author study protocols, development/validation reports, SOPs, and transfer documentation, and provide technical guidance and training during implementation. Communicate project progress, experimental findings, risks, and recommendations to project teams and stakeholders. QUALI

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Illumina is seeking a talented individual to fulfill a Scientist 1 role in next-generation sequencing (NGS) assay research and development. This is a unique opportunity to join a talented team of scientists at the frontier of innovation in spatial transcriptomics. At Illumina you will work in a dynamic, team-oriented environment and help create novel molecular biology assays that support expansion of Illumina’s spatial transcriptomics portfolio Responsibilities Design and execute lab-based experiments using biochemistry and molecular biology skills Troubleshoot and optimize workflows and assays to improve performance Innovate new spatial transcriptomics methods and devise solutions to technical issues Work independently and as part of an interdisciplinary team Effectively communicate experimental results and next steps to team members at regular meetings Maintain detailed records of experimental work and analysis Complete goals within defined timelines Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with th