Senior Backend Software Engineer, AI Observability & Evals Platform (LangSmith)

About Us At LangChain, our mission is to make intelligent agents ubiquitous. We build the foundation for agent engineering in the real world, helping developers move from prototypes to production-ready AI agents that teams can rely on. We began as widely adopted open-source tools and have grown to also offer a platform for building, evaluating, deploying, and operating agents at scale. With $125M raised at Series B from IVP, Sequoia, Benchmark, CapitalG, and Sapphire Ventures, we’re at a stage where we’re continuing to develop new products, growth is accelerating, and all team members have meaningful impact on what we build and how we work together. LangChain is a place where your contributions can shape how this technology shows up in the real world. Today, our platform includes LangSmith (Observability, Evaluation, Deployment, Fleet, and Sandboxes), our open source frameworks (LangChain, LangGraph, and Deep Agents), and the newly launched LangSmith Engine for autonomous agent improvement. We have 100M+ monthly open source downloads, 6,000+ active LangSmith customers, and 5 of the Fortune 10 use LangSmith in production (+ 35% of the Fortune 500 overall), including teams at Klarna, Clay, Coinbase, Workday, Lyft, Cloudflare, Harvey, Rippling, Vanta, LinkedIn, Monday.com, Nvidia, and Bridgewater. About The Team The LangSmith team owns and builds LangChain's core platform for observability, evaluation, and production reliability of AI systems. From tracing and annotation to run rules, evaluations, and beyond, this team owns LangSmith end-to-end. If you want to define what great AI observability looks like at production scale, this is where that work gets done. About the role This role is onsite 5 days/week in Boston, MA We're looking for a Senior Fullstack Engineer to work on LangSmith. In this role, you'll have the opportunity to shape the technical direction of our platform while working closely with our enterprise customers, developer end-users, and cross functional

About Us At LangChain, our mission is to make intelligent agents ubiquitous. We build the foundation for agent engineering in the real world, helping developers move from prototypes to production-ready AI agents that teams can rely on. We began as widely adopted open-source tools and have grown to also offer a platform for building, evaluating, deploying, and operating agents at scale. With $125M raised at Series B from IVP, Sequoia, Benchmark, CapitalG, and Sapphire Ventures, we’re at a stage where we’re continuing to develop new products, growth is accelerating, and all team members have meaningful impact on what we build and how we work together. LangChain is a place where your contributions can shape how this technology shows up in the real world. Today, our platform includes LangSmith (Observability, Evaluation, Deployment, Fleet, and Sandboxes), our open source frameworks (LangChain, LangGraph, and Deep Agents), and the newly launched LangSmith Engine for autonomous agent improvement. We have 100M+ monthly open source downloads, 6,000+ active LangSmith customers, and 5 of the Fortune 10 use LangSmith in production (+ 35% of the Fortune 500 overall), including teams at Klarna, Clay, Coinbase, Workday, Lyft, Cloudflare, Harvey, Rippling, Vanta, LinkedIn, Monday.com, Nvidia, and Bridgewater. About The Team The LangSmith team owns and builds LangChain's core platform for observability, evaluation, and production reliability of AI systems. From tracing and annotation to run rules, evaluations, and beyond, this team owns LangSmith end-to-end. If you want to define what great AI observability looks like at production scale, this is where that work gets done. About The Role (Onsite in Boston) We’re looking to bring on an experienced frontend engineer to develop and enhance new features on LangSmith, our enterprise platform product for LLM application observability, testing, and debugging. What You Will Do Develop new user-facing features using React & Typescript B

About the role Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who want to challenge status quo, and who lead with the desire to translate novel ideas into clinical and commercial product. As the Senior Director, Late-Stage Cell Therapy Process Development, you will report to the Head of Process and Analytical Development and provide strategic, technical leadership for late stage process development of a PSC-derived islet product for Type 1 diabetes. You will build and manage a high performing process development team to develop commercial ready manufacturing processes. You will play a critical role in advancing our pipeline through pivotal process development, technology transfer, process characterization, and commercial readiness, ensuring robust, scalable, and compliant manufacturing processes. Cool Stuff! This role will require onsite leadership in Cambridge, MA. What you’ll do Partner closely with Research to develop 3D stem cell seed train and differentiation processes, including integration of bioreactors and automated and closed technologies and drug product (DP) process-enabling studies including formulation, fill/finish, and cryopreservation. Lead late stage process development for PSC-derived products, ensuring scalability, robustness, quality and regulatory compliance. Lead process characterization and validation activities, leveraging design of experiments (DoE) and Quality by Design (QbD) approaches and support process performance qualification (PPQ). Establish and execute a comparability strategy for pivotal process changes. Enable technology transfer to CDMOs or internal manufacturing, providing technical input and ensuring successful implementation. Author and review CMC sections of regulatory submissions (e.g., IND, BLA) and support regulatory Q&A and inspections. Collaborate and influence partners across multidisciplinary teams (e.g. Research, Analytical Dev

About the role Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who are passionate about delivering the possible to patients, and who lead with the desire to work on novel ideas. As a Senior Director, Business Development, you will report to the Chief Financial Officer to lead and execute key business development initiatives for a publicly traded biotechnology company advancing innovative cell and gene therapy programs. This individual will play a central role in evaluating, structuring, negotiating, and managing transactions that support the company’s long-term growth objectives, including licensing, partnerships, collaborations, co-development arrangements, platform transactions, and other strategic opportunities. What you’ll do Lead or play a central role in the execution of business development transactions, including: in-licensing and out-licensing, co-development and co-commercialization agreements, research collaborations & platform partnerships, option-based deals, key supply agreements, geographic licensing arrangements, and joint ventures or other structured transactions. Coordinate cross-functional diligence processes involving R&D, technical operations/CMC, clinical, regulatory, legal, IP, finance, commercial, and executive leadership. Develop business cases, valuation frameworks, competitive assessments, and transaction rationale to support internal decision-making. Structure, negotiate, and finalize term sheets, letters of intent, confidentiality agreements, and definitive agreements in collaboration with legal and executive leadership. Support preparation of presentations and recommendations for senior management, executive committees, and the Board of Directors. Build and maintain strong relationships with biotechnology peers, pharmaceutical companies and academic institutions. Serve as a key point of contact for existing a

About the role Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who are passionate about delivering the possible to patients, and who lead with the desire to work on novel ideas. As a Senior Manager, FP&A, you will report to the Executive Director, FP&A and play a critical role in linking business activities with financial reporting. You will support finance partnership with leaders in R&D, CMC, and G&A functions, help create financial plans, and promote spending discipline and transparency through insightful analysis and reporting. You will support long-range and annual planning, forecast, close, and management reporting activities, while helping improve the accuracy and efficiency of planning and reporting processes. What you’ll do Support annual budgeting, forecasting, and long-range planning for assigned business functions, partnering with stakeholders and Finance leadership to meet process deadlines and established targets. Prepare monthly variance analyses comparing actuals to forecast and budget; explain and investigate significant discrepancies and identify key business drivers. Support monthly and quarterly close activities related to operating expense management, cash burn analysis, general ledger reviews, headcount reviews, accruals, and related processes. Develop processes, tools, and infrastructure that enable project-level budgeting, resource planning, and portfolio planning. Help rationalize department investments, including headcount, OPEX, and CapEx, within annual and long-term operating plans, and maintain updates needed for forecast deliverables. Analyze inputs such as open purchase orders, invoices, vendor agreements, business feedback, and forecasts to support appropriate recognition of functional expenses in accordance with US GAAP and company po

Senior Designer, Visual Interaction Design In a nutshell: We’re looking for a Senior Visual Interaction Designer to join our Cambridge Studio who is passionate about crafting elegant, thoughtful user experiences, and who brings strong visual design craft to the interactions people have with complex design systems, software, services, and each other. Senior Visual Interaction Designers at IDEO shape how experiences look, feel, and behave. In this role, you’ll translate human-centered insights into clear, compelling interactions and interfaces that are functional, expressive, and meaningful. You’ll balance visual excellence with usability, and bring a distinct visual voice to each design challenge while learning and growing alongside a multidisciplinary team. This is a phenomenal opportunity for designers who are highly self-guided, eager to take on complexity, and motivated to continually sharpen their craft. Once here you will: Contribute to a diverse portfolio of projects spanning data, experience, interaction, digital product, and service design across a range of industries Work across all phases of a project, from research synthesis and concepting through prototyping, refinement, and production-ready execution Translate human-centered insights into interaction models, visual systems, and polished digital interfaces Create “looks-like / works-like” prototypes to explore ideas, test assumptions, and communicate concepts to teammates and client stakeholders Collaborate closely with designers from different backgrounds—including design research, business design, industrial design, and communication design—to develop cohesive, holistic experiences Design across a wide variety of mediums and contexts, such as mobile apps, AI experiences, websites, digital/physical systems, room-scale displays, AR/VR, or voice interfaces, always guided by user needs and context Advocate for high-quality visual and interaction design, contributing to a culture of strong craft, curiosity,