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Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team Our immune cell reprogramming team integrates foundational research on immunology and disease biology with AI-modeling to develop engineered cells that harness our own immune system to detect and treat early signs of age-related diseases, like cancer, Alzheimer’s, and Parkinson’s. These technologies will enable precise, context-dependent therapeutic responses only when and where it is needed. You can learn more about our work here . Our work brings together three powerhouse universities - Columbia University, The Rockefeller University, and Yale University - into a single collaborative technology and discovery engine. Our Vision Pursue large scientific challenges that cannot be pursued in conventional environments Enable individual investigators to pursue their riskiest and most innovative ideas Facilitate research by scientists and clinicians at our home institutions and beyond We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease. The Opportunity The newly established Laboratory of Synthetic Spatial Omics at CZ Biohub NY (https://takeilab.org/) advances our understanding of engineered immune cell function within their native microenvironment to design better cell therapeutic approaches. Toward this goal, we develop and integrate state-of-the-art immune cell engineering, imaging-based and sequencing-based multi-omics, and machine learning/AI frameworks. We bring t

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team Our AI research team sits at the heart of our mission to unlock new dimensions of biological understanding. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology—developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide. Our approach is comprehensive and integrated, bringing together world-class AI model development, exceptional engineering talent, high-quality biological data, powerful computing infrastructure, and strategic partnerships. Success requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools. The Opportunity This is an opportunity to shape the future of biological research by pushing the boundaries of what AI can achieve in science. You’ll work alongside leading experts in AI and biology, with the resources and mandate to tackle some of the most important questions in human health—advancing frontier AI research, accelerating engineering velocity, connecting rich biological data to AI systems, enabling reliable compute acro

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team Our AI research team sits at the heart of our mission to unlock new dimensions of biological understanding. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology—developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide. Our approach is comprehensive and integrated, bringing together world-class AI model development, exceptional engineering talent, high-quality biological data, powerful computing infrastructure, and strategic partnerships. Success requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools. The Opportunity This is an opportunity in the AI Research Wet Lab team to shape the future of biological research by pushing the boundaries of what AI can achieve in science. You’ll work alongside leading experts in AI and biology, with the resources and mandate to tackle some of the most important questions in human health—advancing frontier AI research, connecting rich biological data to AI systems, and translating models and data i

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team The AI Cluster Production Engineering team is part of the AI Compute Platform organization at Biohub, a non-profit research lab committed to open science and open-source AI. We own the design, operation, and reliability of large-scale multi-GPU AI clusters that power frontier AI biology research: protein language models, genomic foundation models, and scientific reasoning systems built to be shared, not monetized. Our clusters run Slurm on Kubernetes infrastructure and support everything from day-to-day AI researcher workflows to multi-node hero training runs at thousands of GPUs. The team works at the intersection of AI tooling, distributed systems, HPC, and frontier AI, debugging deep AI infrastructure problems and building AI systems critical to the entire AI organization. The Opportunity CZ Biohub's mission is to cure or prevent all human disease. Achieving that requires training frontier-scale AI biology models, and that demands reliable, high-performance compute infrastructure. This is production engineering work at a frontier AI lab, with the twist that the mission is biology and the science is open. You'll keep GPU clusters running at high utilization, debug the toughest distributed systems failures, and build the operational foundations for scaling to multi-thousand GPU hero runs. The technical problems are genuinely hard (e.g., multi-node distributed training, InfiniBand fabrics, large-scale storage, Slurm at scale) inside an organization where the work is aimed at helping peop

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world's leading biologists. We're not a startup trying to find product-market fit, and we're not a pharma company optimizing a pipeline. We're building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment. Our research spans: Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond. Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science Imaging foundation models trained across the world's largest microscopy datasets Reasoning and agentic systems that connect frontier LLMs with biological foundation models Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled Join Our Team! As a Research Engineer, you'll build the models and systems that define what AI can do in biology: foundation models, reasoning, reinforcement learning, and multi-agent systems at frontier scale. What You'll Do Build on and advance the AI systems at th

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team Our decoding inflammation team builds tools to enable precise molecular-level measurements of inflammation within human tissues in real time, and develop proactive, early interventions that can be deployed when inflammation — which underlies the most significant causes of death worldwide — first flares in the body. You can learn more about our work here . Our team collaborates with three powerhouse universities - Northwestern University, the University of Chicago, and the University of Illinois Urbana-Champaign - to develop first-in-class technologies and make breakthroughs. Our Vision Pursue large scientific challenges that cannot be pursued in conventional environments Enable individual investigators to pursue their riskiest and most innovative ideas Facilitate research by scientists and clinicians at our home institutions and beyond We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease. The Opportunity The Chan Zuckerberg Biohub Chicago is seeking outstanding early-career scientists to join and participate in the launch of the Proteoform Spatial Biology Group by continuing their training as a Postdoctoral Fellow in Multimodal Modeling. The Proteoform Spatial Biology Group aims to uncover the spatiotemporal regulation of proteins and their unique molecular forms, proteoforms, in inflammation and autoimmunity. For this position, the ideal candidate is expect

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world's leading biologists. We're not a startup trying to find product-market fit, and we're not a pharma company optimizing a pipeline. We're building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment. Our research spans: Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond. Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science Imaging foundation models trained across the world's largest microscopy datasets Reasoning and agentic systems that connect frontier LLMs with biological foundation models Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled Join Our Team! As a Research Scientist, you'll build the models and systems that define what AI can do in biology: foundation models, reasoning, reinforcement learning, and multi-agent systems at frontier scale. What You'll Do Build on and advance the AI systems at t

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world's leading biologists. We're not a startup trying to find product-market fit, and we're not a pharma company optimizing a pipeline. We're building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment. Our research spans: Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond. Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science Imaging foundation models trained across the world's largest microscopy datasets Reasoning and agentic systems that connect frontier LLMs with biological foundation models Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled Join Our Team! As a Research Engineer, you'll build the models and systems that define what AI can do in biology: foundation models, reasoning, reinforcement learning, and multi-agent systems at frontier scale. What You'll Do Build on and advance the AI systems at th

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world's leading biologists. We're not a startup trying to find product-market fit, and we're not a pharma company optimizing a pipeline. We're building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment. Our research spans: Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond. Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science Imaging foundation models trained across the world's largest microscopy datasets Reasoning and agentic systems that connect frontier LLMs with biological foundation models Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled Join Our Team! As a Research Scientist, you'll build the models and systems that define what AI can do in biology: foundation models, reasoning, reinforcement learning, and multi-agent systems at frontier scale. What You'll Do Build on and advance the AI systems at t

About Voyage AI Team at MongoDB Voyage AI team in MongoDB is building a best-in-class, general-purpose, domain-specific, and fine-tuned embedding models and rerankers to enable accurate, efficient unstructured data search and retrieval for RAG, recommendation, semantic search, and more. It is backed by a strong team of AI researchers from Stanford, MIT, Berkeley, Princeton, and CMU, who have conducted over five years of cutting-edge research on training embedding models. Voyage AI was acquired by MongoDB recently, and is now integrating the SOTA embedding models with MongoDB's data platform to create powerful end-to-end solutions. We are looking to speak to candidates who are based in Palo Alto for our hybrid working model. Position Overview We are seeking a Staff Research Scientist to join our team and contribute to the development of next-generation AI models. This position offers a unique opportunity to work on challenging problems at the intersection of machine learning research and practical deployment of large neural networks. This role can be based out of our Palo Alto office, or remotely in the United States. Responsibilities Conduct cutting-edge research in artificial intelligence, from frontier LLMs to embedding models and rerankers Innovate in next-generation information retrieval and LLM agent paradigm Collaborate closely with other research scientists and research engineers as well as peers across the organization Qualifications PhD degree in Computer Science or related field A track record of coming up with new ideas or improving upon existing ideas in machine learning, demonstrated by accomplishments such as first author publications in top venues Strong background in machine learning, deep learning, and natural language processing Experience building complex neural networks for language and visual understanding Capable of conducting rigorous empirical studies to validate theoretical results Excellent leadership, problem-solving, and communication ski

About Voyage AI Team at MongoDB Voyage AI team in MongoDB is building a best-in-class, general-purpose, domain-specific, and fine-tuned embedding models and rerankers to enable accurate, efficient unstructured data search and retrieval for RAG, recommendation, semantic search, and more. It is backed by a strong team of AI researchers from Stanford, MIT, Berkeley, Princeton, and CMU, who have conducted over five years of cutting-edge research on training embedding models. Voyage AI was acquired by MongoDB recently, and is now integrating the SOTA embedding models with MongoDB's data platform to create powerful end-to-end solutions. Position Overview We are seeking a Senior Research Scientist to join our team and contribute to the development of next-generation AI models. This position offers a unique opportunity to work on challenging problems at the intersection of machine learning research and practical deployment of large neural networks. We are looking to speak to candidates who are based in Palo Alto for our hybrid working model. Responsibilities Conduct cutting-edge research in artificial intelligence, from frontier LLMs to embedding models and rerankers Innovate in next-generation information retrieval and LLM agent paradigm Collaborate closely with other research scientists and research engineers as well as peers across the organization Qualifications PhD degree in Computer Science or related field Strong background in machine learning, deep learning, and natural language processing Familiarity with training distributed training of neural networks for language and visual understanding What We Offer Opportunity to work on real-world problems at the cutting edge of AI research Opportunity to utilize research vision to innovate the entire company and make real-world impact Exposure to the full lifecycle of AI model development, from research to production Our compensation (base + equity) for this position is competitive with frontier AI labs About MongoDB

About the Team The Personalization-Memory team, within OpenAI's broader Personal AGI organization, is focused on developing agents that can learn from prior interactions in order to become more helpful and efficient over time. We build general-purpose memory and personalization capabilities that transfer across ChatGPT and other agentic products, and we collaborate with applied engineering on the product surfaces that allow users to interact with memory. About the Role As a Research Engineer / Research Scientist on the Personalization-Memory team, you will research and develop improvements to memory usage and personalization in OpenAI's frontier models. Our team works on reinforcement learning, dataset creation, evaluations, and other post-training methods. We partner closely with research and product teams across the company to realize the vision of a truly personalized ChatGPT. We're looking for individuals who have a background in frontier model post-training, are able to iterate quickly, and who are passionate about product-driven research. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Own and pursue a research agenda for improving memory use and personalization in frontier models. Build robust evaluations for tracking modeling improvements. Design, implement, test, and debug code across our research stack. Collaborate closely with the research and product teams to influence the shape of technical solutions in the product. You might thrive in this role if you: Are passionate about personalization and building personalized assistants. Have experience working with user signals and human data to turn feedback into reliable signals for training and evaluation. Have a deep understanding of frontier model post-training and machine learning applications. Value principled approaches and research craftsmanship. Are comfortable diving into a lar

This role will support the fleet infrastructure team at OpenAI. The fleet team focuses on running the world’s largest, most reliable, and frictionless GPU fleet to support OpenAI’s general purpose model training and deployment. Work on this team ranges from Maximizing GPUs doing useful work by building user-friendly scheduling and quota systems Running a reliable and low maintenance platform by building push-button automation for kubernetes cluster provisioning and upgrades Supporting research workflows with service frameworks and deployment systems Ensuring fast model startup times though high performance snapshot delivery across blob storage down to hardware caching Much more! About the Role As an engineer within Fleet infrastructure, you will design, write, deploy, and operate infrastructure systems for model deployment and training on one of the world’s largest GPU fleet. The scale is immense, the timelines are tight, and the organization is moving fast; this is an opportunity to shape a critical system in support of OpenAI's mission to advance AI capabilities responsibly. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Design, implement and operate components of our compute fleet including job scheduling, cluster management, snapshot delivery, and CI/CD systems. Interface with researchers and product teams to understand workload requirements Collaborate with hardware, infrastructure, and business teams to provide a high utilization and high reliability service You might thrive in this role if you: Have experience with hyperscale compute systems Possess strong programming skills Have experience working in public clouds (especially Azure) Have experience working in Kubernetes Execution focused mentality paired with a rigorous focus on user requirements As a bonus, have an understanding of AI/ML workloads About OpenAI OpenAI is an AI resea

About the Team OpenAI Finance is responsible for ensuring the organization is set up for success in pursuit of its mission to ensure that artificial general intelligence benefits all of humanity. The Controllership team delivers the financial truth that powers OpenAI’s growth. By translating operational activity into accurate, timely, and decision-grade financial data, we enable leadership to scale the business with confidence. Our commitment to rigorous controls and best-in-class systems ensures financial integrity as OpenAI grows. About the Role We are seeking a strategic and execution-oriented Inventory & Cost Accounting Lead to build and scale manufacturing accounting and product costing capabilities across consumer hardware and robotics businesses. This role partners closely with Finance, Supply Chain, Manufacturing Operations, Technical Accounting, Strategic Finance, and Systems teams to establish scalable costing methodologies, inventory valuation processes, manufacturing close procedures, and reporting infrastructure supporting rapid growth and product launches. The ideal candidate brings deep experience in consumer hardware manufacturing environments, including standard costing, inventory accounting, variance analysis, contract manufacturing, and ERP operationalization — particularly within Oracle Fusion. This person should thrive in ambiguity, balance strategic thinking with operational execution, and possess the executive presence and judgment to influence cross-functional stakeholders and senior leadership. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Manufacturing Costing & Inventory Accounting Lead product costing and inventory accounting across consumer hardware and robotics programs, including inventory valuation, manufacturing variances, reserves, and close processes. Partner with Supply Chain, Operations, and Str

About the Team The Privacy Engineering Team at OpenAI is committed to integrating privacy as a foundational element in OpenAI's mission of advancing Artificial General Intelligence (AGI). Our focus is on all OpenAI products and systems handling user data, striving to uphold the highest standards of data privacy and security. We build essential production services, develop novel privacy-preserving techniques, and equip cross-functional engineering and research partners with the necessary tools to ensure responsible data use. Our approach to prioritizing responsible data use is integral to OpenAI's mission of safely introducing AGI that offers widespread benefits. About the Role As a part of the Privacy Engineering Team, you will work on the frontlines of safeguarding user data while ensuring the usability and efficiency of our AI systems. You will help us understand and implement the latest research in privacy-enhancing technologies such as differential privacy, federated learning, and data memorization. Moreover, you will focus on investigating the interaction between privacy and machine learning, developing innovative techniques to improve data anonymization, and preventing model inversion and membership inference attacks. This position is located in San Francisco. Relocation assistance is available. In this role, you will: Design and prototype privacy-preserving machine-learning algorithms (e.g., differential privacy, secure aggregation, federated learning) that can be deployed at OpenAI scale. Measure and strengthen model robustness against privacy attacks such as membership inference, model inversion, and data memorization leaks—balancing utility with provable guarantees. Develop internal libraries, evaluation suites, and documentation that make cutting-edge privacy techniques accessible to engineering and research teams. Lead deep-dive investigations into the privacy–performance trade-offs of large models, publishing insights that inform model-training and prod