Responsibilities: Annotate Case Report Form (acrf.pdf) following FDA/CDISC or sponsor guidelines. Develop SDTM specifications and generate SDTM datasets using SAS; Develop ADaM,specifications and generate ADaM datasets using SAS based on Statistical Analysis Plan; Develop Tables, Listings, Graphs, Patient Profile in support of the Clinical Study Report, Posters, Manuscripts; Develop ADaM data, Tables, Listings, Figures for Integrated Summary of Safety (ISS) and Integrated Summary of Efficacy (ISE) Create electronic submission packages to FDA, e.g., define.xml or define.pdf following FDA guidelines with no supervision. Expert-level in analyze information and develop innovative solutions to programming and data analysis challenges; Serve as point of contact (POC) of programming with statisticians for statistical input and analysis interpretation; Follow and reinforce regulatory agency requirements during daily job. Serve as a programming team lead and contribute to department initiatives. Provide guidance, mentoring, training for team members and help solve issues from cross-functional teams; Review draft and final production deliverables for project to ensure quality and consistency. Work with global team or sponsors to coordinate project deliverables, timelines and resources. Skills and Responsibilities: Bachelor’s/Master’s degree in Statistics, Mathematics, Computer Science, Electrical Engineering, Biotechnology or related scientific disciplines with 5+years of clinical programming experience. Proven knowledge and training in high level computing languages such as. SAS, C/C++, Java, R, Python, MATLAB and SQL. Database programming experience is a plus. Expert-level in decoding programming logic and assembling programming code based on logic provided and be able to explain to team members. Expert level in applying concept in Artificial Intelligence and Machine Learning in real world. In-depth knowledge of ICH, Good Clinical Practices, Clinical research, Clinical tria
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Responsibilities: Annotate Case Report Form (acrf.pdf) following FDA/CDISC or sponsor guidelines. Develop SDTM specifications and generate SDTM datasets using SAS. Develop ADaM specifications and generate ADaM datasets using SAS based on Statistical Analysis Plan. Develop Tables, Listings, Graphs, Patient Profile in support of the Clinical Study Report, Posters, Manuscripts. Develop ADaM data, Tables, Listings, Figures for Integrated Summary of Safety (ISS) and Integrated Summary of Efficacy (ISE). Create electronic submission package to FDA, e.g., define.xml or define.pdf following FDA guidelines with minimum supervision. Proficient in analyze information and develop innovative solutions to programming and data analysis challenges; Support the point of contact (POC) of programming with statisticians for statistical input and analysis interpretation Follow and reinforce regulatory agency requirements during daily job. Serve as a programming team lead and contribute to department initiative. Provide guidance, mentoring, training for team members and help solve issues from cross-functional teams. Review draft and final production deliverables for project to ensure quality and consistency. Skills and Qualifications: Bachelor’s/Master’s degree in Statistics, Mathematics, Computer Science, Electrical Engineering, Biotechnology or related scientific disciplines with at least 4+ years of clinical programming experience. Proven knowledge and training in high level computing languages such as. SAS, C/C++, Java, R, Python, MATLAB and SQL. Database programming experience is a plus. Proficient in decoding programming logic and assembling programming code based on logic provided and be able to explain to team members. Proficient in applying concepts in Artificial Intelligence and Machine Learning in the real world. In-depth knowledge of ICH, Good Clinical Practices, Clinical research, Clinical trial process and related regulatory requirements and terminology. Good understa
Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team The Biohub is a group of nonprofit research institutes that bring together scientists, engineers, and physicians with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons. The Biohub focuses on understanding underlying mechanisms of disease and developing new technologies that will lead to actionable diagnostics and effective therapies. Our Vision We pursue large scientific challenges that cannot be pursued in conventional environments We enable individual investigators to pursue their riskiest and most innovative ideas The technologies developed at the Biohub facilitate research by scientists and clinicians at our home institutions and beyond Diversity of thought, ideas, and perspectives are at the heart of Biohub and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution. The Opportunity The Biohub Chicago is seeking an exceptional Computational Biologist, Spatiotemporal Multi-Omics to join our growing team. We are looking for a creative and collaborative bioinformatics researcher who is excited to build the analytical foundation for our spatiotemporal multi-omics technology platform. What You'll Do Develop data analysis workflows for spatiotemporal and multi-omics datasets. Build visualization tools that enable exploration and interpretation of complex biological data across space and time. Integrate proteo
About the team OpenAI’s mission is to build safe artificial general intelligence (AGI) which benefits all of humanity. This long-term undertaking brings the world’s best scientists, engineers, and business professionals into one lab together to accomplish this. In pursuit of this mission, our Go To Market (GTM) team is responsible for helping customers learn how to leverage and deploy our highly capable AI products across their business. The team is made of Sales, Solutions, Support, Marketing, and Partnership professionals that work together to create valuable solutions that will help bring AI to as many users as possible. About the role As an Account Director focused on Insurance you will own executive-level relationships with leading Insurance organizations. You’ll help these companies safely and effectively deploy OpenAI’s technology to accelerate financial data analysis, automate backend operations, drive AI-powered research, and personalize customer engagement. This role blends literacy, technical depth, business acumen, and relationship-driven enterprise sales. You will collaborate closely with researchers, engineers, and financial services solution strategists to design secure, compliant, and high-impact AI deployments. This role is based in New York City. We use a hybrid work model of three days in the office per week and offer relocation assistance to new employees. In this role, you’ll: Manage a focused portfolio of Financial Services, specifically Insurance accounts, developing long-term strategic account plans. Lead complex, multi-stakeholder sales cycles. Partner with solutions and research engineering to design pilots that demonstrate measurable business impact. Collaborate with compliance, privacy, and security teams to ensure responsible deployment of AI in regulated environments. Own a revenue and consumption target; manage forecasts and pipeline reporting. Monitor industry and regulatory trends to guide customer and product strategy. Represent Ope
About the Team Safety Systems manages the complete lifecycle of safety efforts for OpenAI’s frontier models, ensuring our models are deployed responsibly and have a positive impact on society. Our work spans diverse research and engineering initiatives—from system-level safeguards and model training to evaluation and red-teaming—all aimed at mitigating misuse, misalignment, and maintaining our high bar for safety. We lead OpenAI's commitment to developing and deploying safe Artificial General Intelligence (AGI), fostering a culture of trust, responsibility, and transparency. Our goal is to continuously learn from deployments, distribute AI’s benefits widely, and ensure that powerful tools remain aligned with human values and safety considerations. About the Role We are hiring a Product Manager to focus on risk related to multimodal models. In this role, you will drive initiatives which ensure that OpenAI’s audio, image, and video deployments are safe, impactful, and aligned with user needs and technical innovation. You will clarify strategic priorities, develop safety-focused product roadmaps, and collaborate closely with AI researchers, software engineers, policy experts, and cross-functional partners. This role suits a proactive, technically skilled product manager adept at adversarial thinking and excited to tackle challenging, ambiguous problems through structured analysis and collaborative decision-making. This position is based in San Francisco, CA, with relocation assistance available. In this role, you will: Partner closely with AI research, engineering, data science, policy teams, and other stakeholders to embed safety throughout the development and deployment of multimodal AI models - such as GPT-Live and ChatGPT Images - as well as multimodal capabilities in frontier AI models. Develop comprehensive frameworks for understanding and mitigating deployment safety risks, drawing on data analysis, expert consultation, and adversarial assessments. Define strate
At Lyft, our purpose is to serve and connect. We aim to achieve this by cultivating a work environment where all team members belong and have the opportunity to thrive. Lyft connects people to transportation to change the way we live and get around our communities. We are looking for product managers who bring exceptional creative and analytical skills to drive forward a best in class product. Product management at Lyft leads the integration of engineering, data science, and design to achieve the company’s vision for reinventing transportation. We are looking for entrepreneurial and passionate Product Managers to innovate and execute across a rapidly growing, fast paced company and industry from our San Francisco headquarters. The Core Rider team is responsible for the Lyft consumer app you know and love. This team spans the entire consumer journey across the request and purchase flows, search, pickups and dropoffs, the post-match experience, and the in-trip experience. As a Staff Product Manager on the Core Rider team, you’ll lead a large cross-functional team to build the rider “journey” (anything that gets a rider from A to B.) This includes the home screen, request flow, pickup experience, in-ride experience, and rate & pay. You’ll also be responsible for how this “golden path” experience extends to serve AVs and segments of interest – owning targeted experiences like Lyft Silver for Seniors and Price Lock for commuters. This represents a large percentage of the core Lyft rider experience used by millions of people every day. Plus, the solutions you build need to work everywhere, from the simplest suburban home to JFK Airport, and all modes of transportation (rideshare, AVs, etc.). Responsibilities: Understand Lyft's strategic and competitive position. Set goals and success metrics that align with Lyft's mission and drive maximum impact based on data analysis, market research and usability studies Set an incredibly ambitious vision that motivates and i
Hyliion is committed to creating innovative solutions that enable clean, flexible and affordable electricity production. The Company’s primary focus is to develop distributed power generators that can operate on various fuel sources to future-proof against an ever-changing energy economy. Job Purpose The Senior Strategy & Supply Chain Associate is responsible for proactively assisting in the development of sourcing strategies that are aligned with business and program needs and then driving execution of those strategies while ensuring quality, delivery, and cost targets are exceeding expectations. Duties and Responsibilities Strategic Problem-Solving: Apply a structured, hypothesis-driven approach to diagnose complex supply chain challenges, identify root causes, and develop data-backed solutions. Data Analysis and Modeling: Conduct quantitative analysis using large datasets from our ERP and supply chain data. Develop and maintain analytical models to optimize key supply chain metrics such as inventory levels, lead times, and product economics. Process Optimization and Redesign: Lead high-impact projects to re-engineer core supply chain processes, leveraging best practices to drive significant improvements in efficiency, cost, and resilience. Cross-Functional Collaboration: Serve as a trusted advisor to internal stakeholders in Engineering, Finance, and Operations. Effectively communicate complex analyses and recommendations to senior leadership, fostering alignment and driving execution. Performance Management: Design, implement, and monitor key performance indicators (KPIs) and dashboards to track supply chain health and project performance. Provide regular, insightful reports to management on progress against strategic objectives. Supplier and Sourcing Strategy: Collaborate with the Procurement team to analyze supplier capabilities, assess market dynamics, and develop commodity and category strategies that align with bot
About Us Pearl is AI for professional services at global scale, combining advanced AI with verified human expertise to deliver help that is accurate, accountable, and fast. Since 2003, our network has connected millions of customers with licensed professionals across 196 countries, making real expertise available anytime, anywhere. Our Values Data driven: Start with truth, measure what matters. Courageous: Bias to action; run toward hard problems. Innovative: Seek novel, elegant solutions. Lean: Do more with less. Build, ship, learn fast. Humble: Strong opinions, lightly held. About the Role As a Senior Product Manager at Pearl , you will own discovery, strategy, and execution for high-impact products supporting Pearl Enterprise , with direct responsibility for driving revenue outcomes (including Enterprise contracts totaling $2.5M+). This is a hands-on, high-ownership PM role in a fast-moving, ambiguous environment. You will partner closely with Engineering, AI / Innovation (IL), Sales, and cross-functional stakeholders to define priorities, set OKRs, and deliver results at Pearl-speed. Pearl's product itself is increasingly AI-driven , and while this role does not require you to be an AI engineer, it does require comfort working with AI-powered products, AI prototypes, and AI-enabled teams. What You’ll Do Product Ownership & Execution Own the end-to-end product management role: problem definition, prioritization, roadmap creation, execution, and delivery. Partner with IL / AI leaders to define OKRs, priorities, and quarterly roadmaps aligned to Enterprise goals. Lead agile teams to execute against the roadmap with speed, focus, and accountability. Own releases and delivery using lean and agile practices, balancing experimentation with execution. Discovery, Data & Decision-Making Drive discovery through customer research, data analysis, experimentation, and rapid validation. Define product requirements for MVPs, AI-enabled features, and enhancements.
As a Staff Product Manager on Datadog's Observability Data Platform (ODP) , you will lead product management for a portfolio of foundational platform bets — work that changes the cost structure and capability of the platform itself, not the cost of any single feature. Among ODP’s portfolio of engineering work are efforts to bring the platform's unit cost down meaningfully each quarter, plus a slate of architectural bets aimed at order-of-magnitude cost reduction over the longer horizon. The work you'll lead reshapes how Datadog ingests, routes, and exposes telemetry value to customers — and is foundational to how every product team in Datadog's ecosystem will think about telemetry economics going forward. This role reports to the Group Product Manager of ODP. What You'll Do: Set product direction across foundational platform bets by defining problems and desired outcomes, partnering with engineering to determine slices of work that drive value in phases for users and the business. Collaborate on the long-term cost-and-value architecture of the platform — how value-aware telemetry, innovative data engines, and customer-facing cost stories fit together over multiple quarters. Develop and defend sizing and impact estimates for large, diffuse programs — credibly produce the analysis that engineering leadership and pricing partners need to make resourcing and prioritization calls. Anticipate and communicate market trends in telemetry economics and agentic observability and how they shape platform investment. Develop deep understanding of cost-to-serve by partnering with engineering on the unit economics of the data platform and bring that cost-profile understanding into collaborative discussions with product verticals about customer-facing trade-offs. Surface the customer-positive angles in cost work that engineering-led optimization tickets don't currently make visible. Deliver concise written and verbal communication to executive, engineering, and customer audien
About the Role Anyscale is seeking a Senior / Staff Product Manager to lead Ray Data, our scalable data processing library for ML and AI workloads. This is a uniquely challenging role that requires balancing open source growth with commercial differentiation - driving rapid adoption in the open source Ray Data ecosystem while building compelling proprietary features for Anyscale RunTime, our high-performance commercial engine. You'll own the entire Ray Data product roadmap in a competitive landscape, working closely with the engineering team, the field team, enterprise customers, and the open source community. Success requires: Deeply ingraining yourself into the end-user experience to understand the nature of the product and its gaps and tradeoffs Working closely with customers and open source users to draw the subtle line between growth and commercialization Strategic thinking about which parts of the ML/Data lifecycle to focus on, identifying opportunities where our architectural strengths create the most value. Thinking deeply about and clearly articulating the product strategy to stakeholders Key Responsibilities Drive the Ray Data product roadmap - Balance open source Ray Data feature development with Anyscale Runtime commercial differentiation to ensure that both Ray Data becomes the open source standard for AI data processing and Anyscale Runtime remains sufficiently compelling. Drive open source Ray Data adoption - Focus on community growth, developer experience, and ecosystem integrations Market Positioning & Enablement - Work closely with Product Marketing on strategic market positioning, field enablement, and competitive analysis to maintain differentiation. Customer engagement - Drive key customer engagements assisting sales and field engineering teams. Required Qualifications 4+ years of product management experience with technical products Strong technical background in distributed systems, ML infrastructure, or data processing Experience working
We at NVIDIA seek an Senior Developer Relations, Automated Synthetic Chemistry Science Lead who can coordinate science streams. This role exists at the crossroads of experimental science, optimization, analytical characterization, AI modeling, laboratory automation, and data infrastructure. It demands a practitioner with a background in research who can lead interdisciplinary science teams and accelerate experimentation without compromising scientific quality. What you'll be doing: Coordinate the operating plan across research priorities, technical execution, and program achievements. Convert research objectives into experimental priorities, parameter-space development, campaign planning, and success criteria. Lead research initiatives encompassing synthetic chemistry, catalysis, process chemistry, machine learning, automated systems, and data processing. Build standardized experimental traces capturing successful and unsuccessful outcomes, metadata, quality-control signals, analytical summaries. Guide AI systems for feasibility assessment, outcome prediction, optimization, scope exploration, and campaign orchestration. Integrate automated experimentation, analytical data streams, data curation, model retraining, and campaign decisions into a closed-loop operating model. Establish science-stream governance: build reviews, decision logs, risk and dependency tracking, quality thresholds, and paths for addressing blocking issues. Prepare recurring workstream readouts for program leadership, including scientific progress, critical decisions, cross-team dependencies, resource needs, and unresolved risks. What we need to see: PhD (or equivalent experience) with 10+ years of hands-on experience in experimental science, chemical engineering, material science, robotics, a
At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Snowflake is expanding the boundaries of the Data Cloud to support mission-critical transactional workloads. Our goal is to deliver OLTP capabilities with the performance, reliability, simplicity, and scale customers expect from Snowflake, while creating a seamless experience across transactional and analytical data. We are looking for a Senior Engineering Manager – OLTP to lead engineering teams and leaders building core transactional database technology and the cloud infrastructure required to operate it at scale. You will help define the architecture and roadmap, grow the organization, and drive technology from design through production. AS A SENIOR ENGINEERING MANAGER – OLTP AT SNOWFLAKE, YOU WILL: Set technical and execution strategy for key areas of Snowflake's OLTP platform, translating product goals into architecture, roadmaps, and team plans. Lead and grow multiple engineering teams, developing managers and senior technical leaders while fostering a culture of ownership, technical excellence, and execution. Drive adoption of AI and agentic development practices to improve engineering velocity, quality, and productivity across the software development lifecycle. Drive architecture and technical decisions in areas such as transactions, concurrency control, low-latenc
About THG Ingenuity THG Ingenuity is a fully integrated digital commerce ecosystem, designed to power brands without limits. Our global end-to-end tech platform is comprised of three products: THG Commerce, THG Studios, THG Fulfilment. Each represents a single, unified solution, overcoming challenges and taking brands direct-to-consumer. Our client portfolio includes globally recognised brands such as Coca-Cola, Nestle, Elemis, Homebase, and Proctor & Gamble. About the Role As Maintenance Lead, you’ll play a central role in keeping our fulfilment operation running safely, efficiently and reliably. Working closely with the Engineering and Facilities Site Manager, you’ll lead the site’s planned and reactive maintenance activity while shaping the technical agenda and building a culture of continuous improvement. This is a high-impact leadership role for an experienced engineer who enjoys balancing the demands of a fast-moving operation with the opportunity to develop long-term reliability strategies. You’ll use modern maintenance systems and techniques to improve equipment availability, reduce recurring failures and help our engineering teams perform at their best. What you’ll be doing Support the development and delivery of the site’s maintenance strategy. Lead a reliability-focused approach using TPM, RCA, RCM and FMEA. Deliver monthly improvement plans that increase equipment reliability and availability. Use CMMS data and failure analysis to identify root causes and deliver lasting solutions. Coordinate the response to live plant issues, ensuring risks are managed and actions are followed through. Own effective weekly and monthly maintenance planning, including preventative maintenance compliance and backlog management. Monitor, analyse and report weekly and monthly KPIs, ensuring results are shared with key stakeholders. Coordinate planned maintenance outages and engineer
NVIDIA is seeking a creative and analytical Capacity Planner to join our Operations team and drive the scaling of our Boards & Systems manufacturing across all business units. In this cross-functional role, you will lead the weekly planning cycle, collaborate with Operations, Manufacturing, Supply Chain, Engineering, Finance, and Business Units, and leverage advanced analytical models to resolve capacity constraints, rationalize capital investments, and drive execution strategies for senior management. What You'll Be Doing Run the weekly capacity planning cycle for Boards & Systems, including forecast ingestion, supply planning alignment, Contract Manufacturer (CM) and testing reviews, and preparation of planning outputs. Consolidate and validate core planning inputs (18-month forecasts, NPI consumption, SKU mappings, CM commits, yield data) across enterprise applications like Anaplan. Analyze required versus available capacity, identify bottlenecks, and perform scenario analysis using data models to drive risk mitigation strategies. Lead capital investment, decisions based on capacity requirements, rationalize forecast changes, and optimize volume loading across CMs to meet target supply and revenue goals. Coordinate workflows across Supply Planning, Business Units, Contract Manufacturers, Production Planning, Purchasing, Manufacturing/Test Engineering, Finance, and NPI in a multi-program platform environment. Partner with IT teams to integrate planning models with enterprise systems, establishing standardized workflows, data pipelines, and toolsets. Present clear, data-driven execution plans, operational risk insights, and mitigation strategies to senior management. Align with cross-regional teams (US, Israel, APAC) to maintain seamless operational execution and standardized planning frameworks. What We Need to See 5+ years
Couchbase, the operational data platform for AI, empowers businesses to succeed by bringing data to life in new ways. Major market-leading companies rely on Couchbase for mission critical operational, analytical, mobile and AI workloads. Built to replace legacy infrastructure and fragmented data services, Couchbase empowers enterprises with a unified platform architected for performance, flexibility and global scale. With Couchbase, organizations bring their data to life, launching game‑changing customer experiences, exploring the limitless potential of AI, and seamlessly extending applications from the cloud to the edge and beyond. Couchbase’s AI‑ready technology and enterprise partnership model eliminate complexity and reduce total cost of ownership, enabling teams to stay agile, innovative and secure. Couchbase believes data should never slow you down, but act as the foundation for your next breakthrough. Discover why Couchbase is trusted to help the world’s biggest players scale, move fast and stay resilient, no matter what’s next on their roadmap. Visit couchbase.com and follow us on LinkedIn and X. Want to be part of our story? Apply today! Lead Software Engineer - Storage As a key contributing member of the storage development team, you will be responsible for enhancing the highly scalable and performant storage engines used by both Couchbase Server and Couchbase Capella. You will be developing a highly-available and concurrent enterprise-grade system software. Most of all, you will be able to celebrate the wins by experiencing the direct result of your hard work from our customers’ success stories. The ideal candidate will have a strong technical background, excellent communication skills, and proactive problem-solving skills. The innovative work storage team does has been widely recognized by the industry. The following publications in VLDB conferences reflect the storage work at Couchbase Nitro: A Fast, Scalable In-Memory Storage Engine for NoS
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