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Lead Full Stack Software Development Engineer Jobs

10,000 active opportunities · Updated for October 2026

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Explore current lead full stack software development engineer jobs. Use filters to narrow by work mode, employment type, experience and date posted.

R
Reddit
📍 United States• Remote• $216.7K – $303.4K/yr
3 days ago

Reddit is a community of communities. It’s built on shared interests, passion, and trust, and is home to the most open and authentic conversations on the internet. Every day, Reddit users submit, vote, and comment on the topics they care most about. With 100,000+ active communities and approximately 130 million daily active unique visitors, Reddit is one of the internet’s largest sources of information. For more information, visit www.redditinc.com . Who We Are: The Machine Learning Platform team at Reddit is a high-impact team that owns the infrastructure that powers recommendations, content discovery, user and content quantification, while directly impacting other teams such as Growth, Ads, Feeds, and Core Machine Learning teams. What You’ll Do: As a Senior Software Engineer, ML Platform, you will work on our ML Data Team and be instrumental in architecting, implementing, and maintaining foundational ML infrastructure powering Feeds Ranking, Content Understanding, Recommendations, Ads, and much more to fulfill Reddit’s mission of bringing community and belonging to everyone in the world. You will create ML data-governance tools that help MLEs discover and reason about signals, while contributing across the broader ML data platform—including prediction logging and training data systems. Lead the design, development, testing, and operation of ML signal-governance capabilities that help MLEs discover signals and understand their ownership, lineage, quality, and usage. Build tools that help teams assess signal importance and make informed lifecycle decisions. Partner with MLEs and cross-functional teams to define governance workflows and deliver reliable, intuitive ways to explore and act on signal metadata. Contribute across the ML Data Platform, including prediction logging and training data platforms, to design, develop, test, and operate batch and streaming pipelines processing petabyte-scale data. Drive complex projects end to end from technical planning an

REMOTEmachine learningartificial intelligenceai
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E
Everpure
📍 New York• $111.5K – $184K/yr
3 days ago

Everpure (NYSE: P) has evolved from storage pioneer to data platform, closing fiscal 2026 with $3.7 billion in revenue, its first billion-dollar quarter, and accelerating growth into FY27. Our strategic agenda spans the companies defining the next era of technology - hyperscalers, AI labs, the AI hardware supply chain, data platform providers, and the broader AI ecosystem. This type of work—work that changes the world—is what the tech industry was founded on. So, if you're ready to seize the endless opportunities and leave your mark, come join us. THE ROLE Everpure is seeking an Account Executive with experience selling into Commercial customers in the New York Metro Area. This Account Executive will coordinate the overall strategy and relationship between the assigned accounts and Everpure. They will be responsible for team-selling efforts with other teammates and strategic partners around the globe to close business on a quarterly and annual basis. The ideal candidate will currently be selling and living in the New York Metro Area. WHAT YOU'LL DO Evangelize our radically simple, all-flash enterprise storage technology and data solutions, ensuring customers fully grasp Everpure's total value proposition Build and invest in relationships with customers to establish Everpure's value, continually driving the highest customer satisfaction ratings in the industry Lead pursuit teams and develop account plans to make sure all internal resources are engaged to execute and win new Everpure Customers Drive and manage a healthy and robust pipeline of sales activity to assure quarterly and annual quotas are met or exceeded WHAT YOU BRING Authenticity and a genuine desire to engage customers and understand their business challenges Thought leadership, creativity and a Challenger Mindset; the ability to apply your customer insights and expertise in technology solutions to position Everpure's portfolio to solve persistent problems Avid hunter with proven p

aisupply chain
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B
Baseten
📍 San Francisco• Full-time• Remote• $165K – $330K/yr
3 days ago

ABOUT BASETEN Baseten powers mission-critical inference for the world's most dynamic AI companies, like Cursor, Notion, OpenEvidence, Abridge, Clay, Gamma, and Writer. By uniting applied AI research, flexible infrastructure, and seamless developer tooling, we enable companies operating at the frontier of AI to bring cutting-edge models into production. We're growing quickly and recently raised our $1.5B Series F , led by Altimeter Capital, Conviction Partners, and Spark Capital. Join us and help build the platform engineers turn to ship AI products. THE ROLE Container runtimes were designed for general-purpose software workloads. AI inference is not a general-purpose workload. Running large models at production scale exposes cracks in every layer of the container stack: runtimes unaware of GPU memory constraints, images that take minutes to pull when a model needs to scale to thousands of replicas, and isolation mechanisms that weren’t designed for the multi-tenant serving environments that production AI requires. The tools the industry has relied on for a decade weren’t built for this, and patching around those limitations at higher layers only goes so far. Baseten owns the entire pipeline, from the moment a developer pushes a model to the moment a request gets a response. That vertical ownership means we can fix these problems at the root. The Runtime Fabric team is doing exactly that: purpose-building the container runtime and storage layers for AI inference workloads, led by some of the world’s top containerd maintainers. As Engineering Manager for Storage Products on the Runtime Fabric team, you will lead the engineers who build and run the storage products behind that stack: the Baseten Delivery Network (BDN), which sits in the cold start path of every model on the platform, the snapshotters and filesystems that expose model weights and container images to a running container, and the storage that model deployment and training need next. The team is advancing

REMOTEkuberneteslinuxmachine learning
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Z
3 days ago

Zscaler (NASDAQ: ZS) accelerates digital transformation so customers can be more agile, efficient, resilient, and secure. The Zscaler Zero Trust Exchange platform protects thousands of customers from cyberattacks and data loss by securely connecting users, devices, and applications in any location. Distributed across 200+ public data centers globally and thousands of private sites at the edge, the SASE-based Zero Trust Exchange is the world’s largest in-line cloud security platform. We believe the future of work is Human + AI and are building an AI-native enterprise where human potential is amplified by machine intelligence to solve the world’s hardest security challenges. Driven by deep customer obsession, we are committed to the mission, outcome, and to each other. We bring these commitments to life through three core behaviors: ownership and collaboration, trust through outcomes and impact, and a challenge culture with ongoing feedback. Ready to make an impact at the company pioneering security transformation in the AI era? Join us at Zscaler. We are looking for a Sr. Manager, People Data Infrastructure and Platforms to join our team. This is a Hybrid role located at our Santa Clara, CA HQ or Bellevue, WA office, reporting to the VP, People & Culture AI and Data. In this role, you will lead the evolution of our workforce data ecosystem by establishing a trusted, governed data foundation and scaling intuitive analytics products across the enterprise. You will bridge technical architecture and business execution, partnering with cross-functional teams to eliminate manual reporting dependencies and enable AI-powered workforce intelligence. What you’ll do (Role Expectations) Manage and scale the People data foundation across our enterprise data ecosystem, overseeing workforce data models, pipelines, and data quality on Snowflake to deliver certified, trusted workforce data Establish and enforce data governance and metric certification standards, driving alignment

aiPower BITableau
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P
Pfizer
📍 California• Remote• $108.6K – $250.7K/yr
3 days ago

Pfizer US/PR Commercial Sales Founded in 1849, Pfizer Inc. began as a small chemistry enterprise built on the belief that scientific ingenuity can improve—and protect—human life. Today, as one of the world’s leading biopharmaceutical companies, Pfizer’s purpose is Breakthroughs that change patients’ lives : discovering, developing, and delivering medicines and vaccines that address unmet need, earn trust through quality and integrity, and reach patients through strong partnerships across the healthcare system. In a complex and rapidly evolving pharmaceutical landscape, our work is measured by one outcome - helping patients live longer, healthier lives . Dermatology Organization Mission & Impact Pfizer’s Dermatology organization exists to improve the lives of people living with serious skin disease by connecting scientific innovation to the clinicians and systems that deliver care. We lead with integrity and patient need - promoting Pfizer dermatology products compliantly, helping customers understand appropriate use, and reducing access and workflow barriers so more patients can start and stay on the right therapy. The impact is better, more consistent outcomes for patients and a higher standard of care across the dermatology community. Patient impact at scale: Expand appropriate identification, initiation, and persistence through customer engagement and access pull-through. Market shaping through evidence: Reinforce evidence-based value narratives using approved materials to support informed treatment decisions. Stronger care pathways: Partner across the matrix and with dermatology practic

REMOTEairecruitment
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P
Pfizer
📍 Hawaii• Remote• $108.6K – $250.7K/yr
3 days ago

Pfizer US/PR Commercial Sales Founded in 1849, Pfizer Inc. began as a small chemistry enterprise built on the belief that scientific ingenuity can improve—and protect—human life. Today, as one of the world’s leading biopharmaceutical companies, Pfizer’s purpose is Breakthroughs that change patients’ lives : discovering, developing, and delivering medicines and vaccines that address unmet need, earn trust through quality and integrity, and reach patients through strong partnerships across the healthcare system. In a complex and rapidly evolving pharmaceutical landscape, our work is measured by one outcome - helping patients live longer, healthier lives . Dermatology Organization Mission & Impact Pfizer’s Dermatology organization exists to improve the lives of people living with serious skin disease by connecting scientific innovation to the clinicians and systems that deliver care. We lead with integrity and patient need - promoting Pfizer dermatology products compliantly, helping customers understand appropriate use, and reducing access and workflow barriers so more patients can start and stay on the right therapy. The impact is better, more consistent outcomes for patients and a higher standard of care across the dermatology community. Patient impact at scale: Expand appropriate identification, initiation, and persistence through customer engagement and access pull-through. Market shaping through evidence: Reinforce evidence-based value narratives using approved materials to support informed treatment decisions. Stronger care pathways: Partner across the matrix and with dermatology practic

REMOTEairecruitment
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P
Pfizer
📍 California• Remote• $108.6K – $250.7K/yr
3 days ago

Pfizer US/PR Commercial Sales Founded in 1849, Pfizer Inc. began as a small chemistry enterprise built on the belief that scientific ingenuity can improve—and protect—human life. Today, as one of the world’s leading biopharmaceutical companies, Pfizer’s purpose is Breakthroughs that change patients’ lives : discovering, developing, and delivering medicines and vaccines that address unmet need, earn trust through quality and integrity, and reach patients through strong partnerships across the healthcare system. In a complex and rapidly evolving pharmaceutical landscape, our work is measured by one outcome - helping patients live longer, healthier lives . Dermatology Organization Mission & Impact Pfizer’s Dermatology organization exists to improve the lives of people living with serious skin disease by connecting scientific innovation to the clinicians and systems that deliver care. We lead with integrity and patient need - promoting Pfizer dermatology products compliantly, helping customers understand appropriate use, and reducing access and workflow barriers so more patients can start and stay on the right therapy. The impact is better, more consistent outcomes for patients and a higher standard of care across the dermatology community. Patient impact at scale: Expand appropriate identification, initiation, and persistence through customer engagement and access pull-through. Market shaping through evidence: Reinforce evidence-based value narratives using approved materials to support informed treatment decisions. Stronger care pathways: Partner across the matrix and with dermatology practic

REMOTEairecruitment
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P
Pfizer
📍 California• Remote• $108.6K – $250.7K/yr
3 days ago

Pfizer US/PR Commercial Sales Founded in 1849, Pfizer Inc. began as a small chemistry enterprise built on the belief that scientific ingenuity can improve—and protect—human life. Today, as one of the world’s leading biopharmaceutical companies, Pfizer’s purpose is Breakthroughs that change patients’ lives : discovering, developing, and delivering medicines and vaccines that address unmet need, earn trust through quality and integrity, and reach patients through strong partnerships across the healthcare system. In a complex and rapidly evolving pharmaceutical landscape, our work is measured by one outcome - helping patients live longer, healthier lives . Dermatology Organization Mission & Impact Pfizer’s Dermatology organization exists to improve the lives of people living with serious skin disease by connecting scientific innovation to the clinicians and systems that deliver care. We lead with integrity and patient need - promoting Pfizer dermatology products compliantly, helping customers understand appropriate use, and reducing access and workflow barriers so more patients can start and stay on the right therapy. The impact is better, more consistent outcomes for patients and a higher standard of care across the dermatology community. Patient impact at scale: Expand appropriate identification, initiation, and persistence through customer engagement and access pull-through. Market shaping through evidence: Reinforce evidence-based value narratives using approved materials to support informed treatment decisions. Stronger care pathways: Partner across the matrix and with dermatology practic

REMOTEairecruitment
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P
Pfizer
📍 California• Remote• $108.6K – $250.7K/yr
3 days ago

Pfizer US/PR Commercial Sales Founded in 1849, Pfizer Inc. began as a small chemistry enterprise built on the belief that scientific ingenuity can improve—and protect—human life. Today, as one of the world’s leading biopharmaceutical companies, Pfizer’s purpose is Breakthroughs that change patients’ lives : discovering, developing, and delivering medicines and vaccines that address unmet need, earn trust through quality and integrity, and reach patients through strong partnerships across the healthcare system. In a complex and rapidly evolving pharmaceutical landscape, our work is measured by one outcome - helping patients live longer, healthier lives . Dermatology Organization Mission & Impact Pfizer’s Dermatology organization exists to improve the lives of people living with serious skin disease by connecting scientific innovation to the clinicians and systems that deliver care. We lead with integrity and patient need - promoting Pfizer dermatology products compliantly, helping customers understand appropriate use, and reducing access and workflow barriers so more patients can start and stay on the right therapy. The impact is better, more consistent outcomes for patients and a higher standard of care across the dermatology community. Patient impact at scale: Expand appropriate identification, initiation, and persistence through customer engagement and access pull-through. Market shaping through evidence: Reinforce evidence-based value narratives using approved materials to support informed treatment decisions. Stronger care pathways: Partner across the matrix and with dermatology practic

REMOTEairecruitment
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P
Pfizer
📍 California• Remote• $108.6K – $250.7K/yr
3 days ago

Pfizer US/PR Commercial Sales Founded in 1849, Pfizer Inc. began as a small chemistry enterprise built on the belief that scientific ingenuity can improve—and protect—human life. Today, as one of the world’s leading biopharmaceutical companies, Pfizer’s purpose is Breakthroughs that change patients’ lives : discovering, developing, and delivering medicines and vaccines that address unmet need, earn trust through quality and integrity, and reach patients through strong partnerships across the healthcare system. In a complex and rapidly evolving pharmaceutical landscape, our work is measured by one outcome - helping patients live longer, healthier lives . Dermatology Organization Mission & Impact Pfizer’s Dermatology organization exists to improve the lives of people living with serious skin disease by connecting scientific innovation to the clinicians and systems that deliver care. We lead with integrity and patient need - promoting Pfizer dermatology products compliantly, helping customers understand appropriate use, and reducing access and workflow barriers so more patients can start and stay on the right therapy. The impact is better, more consistent outcomes for patients and a higher standard of care across the dermatology community. Patient impact at scale: Expand appropriate identification, initiation, and persistence through customer engagement and access pull-through. Market shaping through evidence: Reinforce evidence-based value narratives using approved materials to support informed treatment decisions. Stronger care pathways: Partner across the matrix and with dermatology practic

REMOTEairecruitment
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P
Pfizer
📍 California• Remote• $108.6K – $250.7K/yr
3 days ago

Pfizer US/PR Commercial Sales Founded in 1849, Pfizer Inc. began as a small chemistry enterprise built on the belief that scientific ingenuity can improve—and protect—human life. Today, as one of the world’s leading biopharmaceutical companies, Pfizer’s purpose is Breakthroughs that change patients’ lives : discovering, developing, and delivering medicines and vaccines that address unmet need, earn trust through quality and integrity, and reach patients through strong partnerships across the healthcare system. In a complex and rapidly evolving pharmaceutical landscape, our work is measured by one outcome - helping patients live longer, healthier lives . Dermatology Organization Mission & Impact Pfizer’s Dermatology organization exists to improve the lives of people living with serious skin disease by connecting scientific innovation to the clinicians and systems that deliver care. We lead with integrity and patient need - promoting Pfizer dermatology products compliantly, helping customers understand appropriate use, and reducing access and workflow barriers so more patients can start and stay on the right therapy. The impact is better, more consistent outcomes for patients and a higher standard of care across the dermatology community. Patient impact at scale: Expand appropriate identification, initiation, and persistence through customer engagement and access pull-through. Market shaping through evidence: Reinforce evidence-based value narratives using approved materials to support informed treatment decisions. Str

REMOTEairecruitment
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P
Pfizer
📍 California• Remote• $108.6K – $250.7K/yr
3 days ago

Pfizer US/PR Commercial Sales Founded in 1849, Pfizer Inc. began as a small chemistry enterprise built on the belief that scientific ingenuity can improve—and protect—human life. Today, as one of the world’s leading biopharmaceutical companies, Pfizer’s purpose is Breakthroughs that change patients’ lives : discovering, developing, and delivering medicines and vaccines that address unmet need, earn trust through quality and integrity, and reach patients through strong partnerships across the healthcare system. In a complex and rapidly evolving pharmaceutical landscape, our work is measured by one outcome - helping patients live longer, healthier lives . Dermatology Organization Mission & Impact Pfizer’s Dermatology organization exists to improve the lives of people living with serious skin disease by connecting scientific innovation to the clinicians and systems that deliver care. We lead with integrity and patient need - promoting Pfizer dermatology products compliantly, helping customers understand appropriate use, and reducing access and workflow barriers so more patients can start and stay on the right therapy. The impact is better, more consistent outcomes for patients and a higher standard of care across the dermatology community. Patient impact at scale: Expand appropriate identification, initiation, and persistence through customer engagement and access pull-through. Market shaping through evidence: Reinforce evidence-based value narratives using approved materials to support informed treatment decisions. Str

REMOTEairecruitment
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P
Pfizer
📍 California• Remote• $108.6K – $250.7K/yr
3 days ago

Pfizer US/PR Commercial Sales Founded in 1849, Pfizer Inc. began as a small chemistry enterprise built on the belief that scientific ingenuity can improve—and protect—human life. Today, as one of the world’s leading biopharmaceutical companies, Pfizer’s purpose is Breakthroughs that change patients’ lives : discovering, developing, and delivering medicines and vaccines that address unmet need, earn trust through quality and integrity, and reach patients through strong partnerships across the healthcare system. In a complex and rapidly evolving pharmaceutical landscape, our work is measured by one outcome - helping patients live longer, healthier lives . Dermatology Organization Mission & Impact Pfizer’s Dermatology organization exists to improve the lives of people living with serious skin disease by connecting scientific innovation to the clinicians and systems that deliver care. We lead with integrity and patient need - promoting Pfizer dermatology products compliantly, helping customers understand appropriate use, and reducing access and workflow barriers so more patients can start and stay on the right therapy. The impact is better, more consistent outcomes for patients and a higher standard of care across the dermatology community. Patient impact at scale: Expand appropriate identification, initiation, and persistence through customer engagement and access pull-through. Market shaping through evidence: Reinforce evidence-based value narratives using approved materials to support informed treatment decisions. Stronger care pathways: Partner across the matrix and with dermatology practic

REMOTEairecruitment
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I
Illumina
📍 California• $129.4K – $194K/yr
3 days ago

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Exciting opportunity to serve as the Program Manager for Illumina's High Throughput Sequencing (HTS) portfolio, including NovaSeq X and NovaSeq 6000 platforms. The Staff Program Manager is responsible for driving execution of on-market platform priorities, sustaining initiatives, product improvements, lifecycle management activities, and cross-functional governance across Development, Quality, Operations, Regulatory, Commercial, Service, and Supply Chain organizations. This role serves as a key operational partner to the Product Technical Lead and platform leadership team, translating strategic priorities into executable plans and ensuring timely delivery of critical initiatives that improve customer experience, platform reliability, quality, compliance, operational efficiency, and business performance. Operating in a highly matrixed environment, the ideal candidate is an experienced program leader with exceptional planning, communication, risk management, and stakeholder management skills who can independently lead complex cross-functional initiatives and influence decisions across multiple organizations Responsibilities

artificial intelligenceaiPMP
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I
Illumina
📍 California• $129.4K – $194K/yr
3 days ago

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Position Summary Illumina is seeking a Manager, R&D Strategic Partnerships with strong program management expertise to lead execution across complex, R&D strategic partnerships and strategic account programs. This role will translate strategic objectives and partner commitments into actionable program plans, establish effective governance, guide cross-functional teams, and coordinate delivery across R&D and other functions. Depending on the partnership model, the role may also manage the external partner relationship and lead formal joint governance. Because the portfolio is evolving, the successful candidate must be comfortable bringing structure to ambiguity, working independently, managing multiple programs, and communicating effectively with internal leaders and external stakeholders. Key Responsibilities Program leadership: Serve as the accountable program manager for assigned partnerships, determin

artificial intelligenceai
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