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Principal Scientist Jobs

1,489 active opportunities · Updated for October 2026

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Explore current principal scientist jobs. Use filters to narrow by work mode, employment type, experience and date posted.

S
1mo ago

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Snowflake's Data Engineering organization builds the platform that ingests, transforms, and stores data for modern lakehouse architectures — powering billions of queries, DML, and DDL operations with industry-leading price-performance. We lead the industry's shift to open data lakes through our work on Iceberg and Polaris, and we deliver capabilities like Snowpark, Dynamic Tables, cross-region replication, time travel, and zero-copy cloning at enterprise scale. We are investing in a new line of applied research — building toward verified data infrastructure and trustworthy data systems — that brings formal methods, automated reasoning, and modern AI techniques to bear on the hardest problems in our distributed systems and developer tooling. The goal is to improve correctness, reliability, and engineering velocity at a scale very few platforms operate at. We're hiring at both the Staff and Principal level; we'll calibrate the offer to the candidate's experience and scope of impact. What you'll do Lead research projects that apply formal methods, program analysis, automated reasoning, and AI-driven techniques (including code generation and modeling) to real problems in our cloud data platform. Translate research ideas into prototypes, then into shipped capabilities that move

aigorust
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What you’ll do Partner with medical image reconstruction scientists / engineers to build ML components that improve reconstruction quality, speed, robustness, or quantitative accuracy. Define training/evaluation pipelines, datasets, and metrics that map to user needs and design requirements. Productionize models: inference performance, reproducibility, monitoring for drift/regressions, and safe fallbacks. Collaborate on hybrid algorithms, incorporating physics and learned priors, denoisers, learned regularizers, and quality estimation. Help build tooling for rapid experimentation as well as rigorous verification of algorithm changes. What we’re looking for Strong applied ML experience plus comfort with signal processing / imaging or adjacent domains. Ability to move fluidly between research prototypes and production-quality systems. Strong evaluation discipline: metrics, ablations, data leakage avoidance, and reproducibility. A demonstrated track record of applying ML to physics-based or inverse problems (i.e., shipped projects, a portfolio, or publications.) Useful experience ML for imaging/inverse problems (or adjacent) with strong evaluation discipline and comfort with GPU performance constraints. Pragmatic production mindset: reproducible training/inference, regression testing, and safe deployment in high-stakes contexts. A background in computational physics or scientific computing. Leverage ML-based methods such as PiNNs and Neural Operators to solve partial differential equations arising in ultrasound simulation and imaging. Experience in Agentic-SciML is a plus. Hands-on experience with data curation for ML: building datasets from messy, real-world sources, defining ground truth, and managing labeling or simulation pipelines. Background in data assimilation: combining observations with physics-based models (Kalman filtering, variational methods, ensemble approaches, or learned variants).

B
Biohub
📍 Redwood City• Full-time• Hybrid• $214K – $268K/yr
1mo ago

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team Through our multi-dimensional imaging program, we build imaging tools that capture life across scales — from single proteins to whole organisms — revealing how proteins and cells function, communicate, and assemble into living systems. These observations are laying the groundwork for a new generation of AI models that can predict cellular behavior and guide the development of better treatments for widespread diseases. You can learn more about our work here . Our work brings together three powerhouse universities - Stanford, UC Berkeley, and UC San Francisco - into a single collaborative technology and discovery engine. Our Vision Pursue large scientific challenges that cannot be pursued in conventional environments Enable individual investigators to pursue their riskiest and most innovative ideas Facilitate research by scientists and clinicians at our home institutions and beyond We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease. The Opportunity Biohub is seeking an experienced Technical Project Manager to support the VP of Imaging in leading cross-functional teams to plan, execute, and deliver ambitious imaging science and technology projects. The ideal candidate will combine strong technical knowledge with exceptional project management skills to guide complex initiatives from conception to completion. This is ideal for a TPM who takes pride in discipli

restaigo
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A
21 days ago

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 122,000 colleagues serve people in more than 160 countries. JOB DESCRIPTION: Working at Abbott At Abbott, you can do work that matters, grow, and learn, care for yourself and your family, be your true self, and live a full life. You’ll also have access to: Career development with an international company where you can grow the career you dream of. Employees can qualify for free medical coverage in our Health Investment Plan (HIP) PPO medical plan in the next calendar year. An excellent retirement savings plan with a high employer contribution Tuition reimbursement, the Freedom 2 Save student debt program, and FreeU education benefit - an affordable and convenient path to getting a bachelor’s degree. A company recognized as a great place to work in dozens of countries worldwide and named one of the most admired companies in the world by Fortune. A company that is recognized as one of the best big companies to work for as well as the best place to work for diversity, working mothers, female executives, and scientists. The Opportunity The Principal Product Manager for Enterprise Developer Experience defines the vision, strategy, and roadmap for t

aiprocurement
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Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 122,000 colleagues serve people in more than 160 countries. JOB DESCRIPTION: Working at Abbott At Abbott, you can do work that matters, grow, and learn, care for yourself and your family, be your true self, and live a full life. You’ll also have access to: Career development with an international company where you can grow the career you dream of. Employees can qualify for free medical coverage in our Health Investment Plan (HIP) PPO medical plan in the next calendar year. An excellent retirement savings plan with a high employer contribution. Tuition reimbursement, the Freedom 2 Save student debt program, and FreeU education benefit - an affordable and convenient path to getting a bachelor’s degree. A company recognized as a great place to work in dozens of countries worldwide and named one of the most admired companies in the world by Fortune. A company that is recognized as one of the best big companies to work for as well as the best place to work for diversity, working mothers, female executives, and scientists. The Opportunity This position works out of our Alameda, CA location in the Diabetes Care division where we are focused on helping people with diabetes manage their health with life-changing prod

pythonsqlPower BI
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Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 115,000 colleagues serve people in more than 160 countries. JOB DESCRIPTION: Working at Abbott At Abbott, you can do work that matters, grow, and learn, care for yourself and family, be your true self and live a full life. You’ll also have access to: Career development with an international company where you can grow the career you dream of Employees can qualify for free medical coverage in our Health Investment Plan (HIP) PPO medical plan in the next calendar year. An excellent retirement savings plan with high employer contribution Tuition reimbursement, the Freedom 2 Save student debt program and FreeU education benefit - an affordable and convenient path to getting a bachelor’s degree A company recognized as a great place to work in dozens of countries around the world and named one of the most admired companies in the world by Fortune A company that is recognized as one of the best big companies to work for as well as a best place to work for diversity, working mothers, female executives, and scientists Abbott Vascular provides innovative, minimally invasive and cost-effective products for treatment of vascular disease. Our extensive portfolio includes drug-eluting stents, bare metal stents, guide wires, balloon dilatation catheters, imaging catheters and s

supply chain
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R
Roblox
📍 San Mateo• Full-time• From $295.3K/yr
1mo ago

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. ML Platform @ Roblox today supports hundreds of ML use cases and billions of inferences per day across Discovery, Safety, Engine, and much more. As a Model Optimization engineer on ML Platform, you will be responsible for digging deep into model internals to optimize performance, for both training and inference. We are looking for accomplished engineers to help us maximize performance of our platform. You Will: Optimize machine learning models for performance on GPU architectures, focusing on both training and inference workflows. Conduct low-level performance profiling analysis to identify bottlenecks in existing machine learning pipelines and propose actionable improvements. Contribute to the development of best practices and tooling for model optimization and deployment. Collaborate with cross-functional teams, including data scientists and software engineers, to integrate and deploy optimized models into production environments. Partner across organizations to build tooling, interfaces, and visualizations that make the ML@Roblox a delight to use. You Have: 6+ years of professional experience and a tool chest of system design experience upon which to draw to build performant system

awsgitmachine learning
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R
Roblox
📍 San Mateo• Full-time• From $278.5K/yr
1mo ago

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. ML Platform @ Roblox today supports hundreds of ML use cases and billions of inferences per day across Discovery, Safety, Engine, and much more. As an Infrastructure Engineer on the ML Platform team, you will design, scale, and maintain the foundational infrastructure powering our entire machine learning ecosystem. We are looking for accomplished engineers to spearhead the development of our next-generation ML tooling and platform capabilities. You will: Bootstrap and maintain Kubernetes and Cloud infrastructure for ML Platform components--Serving Layer, Metadata Store, Model Registry, and Pipeline Orchestrator. Set technical strategy and oversee development of high scale and reliable infrastructure systems. Propose and implement new platform tooling to improve time to production for MLEs and Data Scientists across the full ML lifecycle. Work on infrastructure projects such as GPU fleet management, hybrid-cloud orchestration, and writing custom Kubernetes controllers and resources. Stay abreast of industry trends in machine learning and infrastructure to ensure the adoption of leading-edge technologies and practices. Partner across organizations to build tooling, interfaces, and visualizati

awsgcpdocker
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Reddit is a community of communities. It’s built on shared interests, passion, and trust, and is home to the most open and authentic conversations on the internet. Every day, Reddit users submit, vote, and comment on the topics they care most about. With 100,000+ active communities and approximately 130 million daily active unique visitors, Reddit is one of the internet’s largest sources of information. For more information, visit www.redditinc.com . Reddit’s Ads Data Science team is looking for a Senior Staff Data Scientist to lead the scientific strategy behind Reddit’s ads measurement and signal systems. This role sits at the center of how Reddit proves advertiser value, improves signal quality, builds privacy-aware measurement systems, and connects ads exposure to real advertiser outcomes. As a Senior Staff Data Scientist for Ads Measurement, you will be the principal architect of our technical vision and the driving force behind the next generation of our measurement ecosystem. In a landscape rapidly shifting due to privacy regulations, browser changes, and evolving platform dynamics, you will spearhead innovation across experimental design (incrementality/lift), identity, signals, and privacy-safe 1P/3P measurement. This is a high-visibility, high-impact role requiring a rare blend of deep experimentation & causal inference expertise, strategic foresight, and the ability to influence cross-functional executives and industry standards. You will not just adapt to the changing ad-tech environment, you will redefine how we measure value. Responsibilities Technical Vision & Strategy: Define the long-term data science vision & strategy across ads measurement, signal quality, identity, attribution, and privacy. Establish how Reddit should evaluate advertiser value, measurement quality, and signal utility across first-party and third-party products. Set the Cross-Pillar Measurement Science Strategy: Define the long-term data science strategy across a

pythonsqlrest
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S
1mo ago

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. We're looking for a Director of Engineering to join our leadership team in the AI Functions product portfolio, a hybrid director/principal engineer role at the forefront of AI-powered analytics. Our mission is to democratize AI by surfacing powerful AI functions directly in SQL for analyzing structured and unstructured data, with minimal configuration. We handle the full AI lifecycle behind the scenes, so data analysts, engineers, and scientists can build data transformation pipelines with AI using the most sophisticated building blocks seamlessly within their existing SQL workflows. The AI Functions product portfolio represents one of the most strategic and impactful product surfaces within Snowflake, bringing together two of the company's core strengths: its industry-leading ability to process massive volumes of data and its growing capability to make that data AI-ready. By embedding advanced AI and LLM-powered functions directly into SQL, this portfolio transforms Snowflake from a data platform into an intelligent data system where structured and unstructured data can be seamlessly prepared, enriched, and analyzed using AI at scale. This convergence enables customers to operationalize AI within their existing workflows, unlocking faster insights, more powerful applicatio

F
Fin
📍 Dublin• Full-time
1mo ago

Fin is the AI Customer Agent company on a mission to help businesses provide perfect customer experiences. Our AI Agent Fin is the highest-performing AI Customer Agent on the market today, enabling businesses to deliver impeccable, always-on customer support across the customer journey – from service, to sales, to ecommerce. Powered by our own AI models, Fin resolves complex customer issues end-to-end across every channel, with minimal set-up and integration. Fin can also be combined with our natively integrated Intercom help desk for one single system that is designed to meet the needs of modern day support teams. Founded in 2011, Fin became one of the fastest growing companies and remains one of the largest private software companies in the world with nearly 30,000 global businesses using our products to transform their customer support. Driven by our core values, we push boundaries, build with speed and intensity, and relentlessly deliver incredible value to our customers. We are looking for a technically-capable product leader to head up AI Design at Fin. Fin is the #1 AI agent for customer service — a full-stack, vertically integrated AI system powered by our own in-house models, Apex, designed specifically for customer experiences. The role is to lead the Design function within our AI Group, where our custom models and core Fin functionality are developed. You will be managing our AI Designers (currently 3 Staff/Principal level AI Designers). You will work directly with AI Engineers and Scientists in our AI Group , and Product Designers and teams in our R&D group. We believe that leading AI Design is a new type of product leadership role that combines technical, product, and leadership qualities. This includes shaping how the Fin AI models and harness behave — how they reason, respond, and improve over time. The experience is defined as much by model behavior, evals, and iteration loops as it is by UI. We’re looking for someone to lead in that world.

restaigo
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N
23 days ago

We are hiring senior engineers to work on the CUDA driver, a core component of our platform for accelerating general purpose computation on the GPU. Our team delivers features and improvements to better realize the potential of NVIDIA hardware for a growing range of computational workloads, ranging from deep learning, scientific computation, and self-driving cars to video games and virtual reality! CUDA defines a unified programming model across a range of system configurations and hardware capabilities. To accomplish this, the CUDA driver interacts with GPU hardware, kernel mode drivers, switches and the operating system. What you'll be doing: As a member of our team, you will use your design abilities, coding expertise, and creativity to deliver the best Compute platform in the world. You will craft elegant solutions to exciting problems and craft the future direction of CUDA as you collaborate with your peers across NVIDIA. You will evangelize, architect, and implement new CUDA features You'll oversee and drive development efforts across multiple teams Collaborate with members of hardware architecture teams Help define forward-looking improvements to the CUDA APIs and programming model Design and maintain performance and precision modeling Write effective, maintainable, and well-tested code Develop code for multiple operating systems What we need to see: Bachelor of Science or Master of Science degree in Computer Science, Electrical Engineering, or related field (or equivalent experience) 15&#43; years of relevant systems software development experience Strong C programming skills </

artificial intelligenceai
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For over 20 years, Smartsheet has empowered teams to manage work seamlessly and scale solutions smarter. Now, in our most ambitious chapter yet, we are uniting human teams with AI agents. By orchestrating the work agents do best, automating manual tasks and uncovering insights at scale, we create the space for people to focus on what truly matters: judgment, creativity, and big thinking. That is magic at work, and it’s what we show up for every day. Smartsheet is hiring a Senior Analytics Engineer to lead the way in data-driven decision-making. You will be responsible for the creation and maintenance of a governed, reliable, and scalable analytics system, transforming raw data into usable datasets for DS/ML, analytics, and reporting. A key aspect of this role is leading the architecture and implementation of efficient data transformation systems within Snowflake, fostering data democratization and impacting business outcomes. Working closely with BI analysts and Data scientists, you will ensure data accessibility and drive activation on critical customer-facing platforms. This full-time position reports to the Director of Analytics Engineering and is based in Smartsheet’s corporate offices in Bengaluru, India. You Will: Leading the implementation of efficient and scalable systems that optimize data transformations from our data lake in Snowflake into clean, documented data products. Contribute to the design standards and architectural principle standards, designs and processes. Build and maintain a governed, robust, reliable, and scalable analytics system (DW/DV). Collaborating with BI analysts and data scientists to provide proper data accessibility guidelines. Foster data democratization via activation of data on critical platforms like Smartsheet platform, Amplitude, Thoughtspot , Gainsight. Create and contribute to frameworks that improve data quality and observability to identify and resolve issues faster. Create and implement data testing plans, en

sqlawsci/cd
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ABOUT THE BRAND: Callaway Golf Company is a premium golf equipment, gear and apparel company with a portfolio of global brands, including Callaway Golf, Odyssey, TravisMathew, and OGIO. Through an unwavering commitment to innovation and premium craftsmanship, Callaway designs, manufactures, and sells high-performance golf clubs, golf balls, apparel, bags, and other accessories—setting the standard for performance in the game of golf. Our Mission: To create demonstrably superior and pleasingly different products powered by innovative technology and premium craftsmanship enabling golfers of all abilities to play their best and find more joy in the game. Our company is a blend of experience and diverse backgrounds, and together we look to leave the past behind while moving the game forward. For more information, please visit https://www.callawaygolf.com ROLES AND RESPONSIBILITIES: Provide business insight into the workings of SAP Sales and Distribution functionality Manage the design, development, and implementation of global business solutions. Establish, grow, and enhance collaborative relationships with regional and global business leads. Provide value-added input and alternatives and facilitate requirements definition whenever appropriate. Manage multiple projects/solutions/support for multiple business areas. Collaborate within the department to ensure alignment and adherence to goals. Collaborate with business areas to understand needs and develop or introduce solutions to maximize value. Act as an active change agent within the organization challenging the team and business to improve and excel. <

SAPExcelproject management
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ABOUT THE BRAND: Callaway Golf Company is a premium golf equipment, gear and apparel company with a portfolio of global brands, including Callaway Golf, Odyssey, TravisMathew, and OGIO. Through an unwavering commitment to innovation and premium craftsmanship, Callaway designs, manufactures, and sells high-performance golf clubs, golf balls, apparel, bags, and other accessories—setting the standard for performance in the game of golf. Our Mission: To create demonstrably superior and pleasingly different products powered by innovative technology and premium craftsmanship enabling golfers of all abilities to play their best and find more joy in the game. Our company is a blend of experience and diverse backgrounds, and together we look to leave the past behind while moving the game forward. For more information, please visit https://www.callawaygolf.com ROLES AND RESPONSIBILITIES Lead the design, configuration, implementation, and support of the SAP Analytics Cloud (SAC) Application for developing and supporting the planning and analytics functions. Lead the implementation and support of SAP’s Business Intelligence solutions. Lead all phases of the project life cycle including analysis, design, development, testing, deployment, and post-production support/maintenance. <l

SAPPower BIfinance
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