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Senior Lead Program Manager Jobs

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ClinChoice is a global full-service CRO committed to professional growth and a quality-driven “one-team” culture. We are seeking a Senior/ Principal Statistician to join our in-house team and support projects across a diverse client portfolio, including pharmaceutical, biotechnology, medical device, and consumer health companies of varying sizes. We are seeking an experienced Senior/Principal Statistician Consultant to provide statistical leadership and expertise across clinical development programs within the pharmaceutical industry. The successful candidate will contribute to clinical trial design, statistical methodology, data analysis, and regulatory submissions while collaborating with cross-functional teams to support evidence generation and informed decision-making throughout drug development. Key Responsibilities Provide statistical leadership across clinical development programs, from early-phase studies through late-phase clinical trials. Lead clinical trial design, including endpoint selection, sample size calculations, power analyses, and randomization strategies. Develop and review clinical study protocols, statistical analysis plans (SAPs), and other statistical documentation. Oversee statistical analyses and interpretation of clinical trial data to ensure scientific rigor and regulatory compliance. Provide statistical expertise for regulatory submissions and interactions with health authorities, including the FDA and EMA. Collaborate with Clinical Development, Clinical Operations, Data Management, Regulatory Affairs, and Medical Writing teams. Review statistical outputs, including tables, listings, and figures (TLFs), to ensure accuracy and consistency with analysis plans. Apply appropriate statistical methodologies to address complex clinical trial design and analysis challenges. Contribute to clinical study reports (CSRs), integrated summaries of safety and efficacy, and other regulatory documents. Identify statistical risks and recommend appropriat

ClinChoice is a global full-service CRO committed to professional growth and a quality-driven “one-team” culture. We are seeking a Senior/ Principal Statistician to join our in-house team and support projects across a diverse client portfolio, including pharmaceutical, biotechnology, medical device, and consumer health companies of varying sizes. We are seeking an experienced Senior/Principal Statistician Consultant to provide statistical leadership and expertise across clinical development programs within the pharmaceutical industry. The successful candidate will contribute to clinical trial design, statistical methodology, data analysis, and regulatory submissions while collaborating with cross-functional teams to support evidence generation and informed decision-making throughout drug development. Key Responsibilities Provide statistical leadership across clinical development programs, from early-phase studies through late-phase clinical trials. Lead clinical trial design, including endpoint selection, sample size calculations, power analyses, and randomization strategies. Develop and review clinical study protocols, statistical analysis plans (SAPs), and other statistical documentation. Oversee statistical analyses and interpretation of clinical trial data to ensure scientific rigor and regulatory compliance. Provide statistical expertise for regulatory submissions and interactions with health authorities, including the FDA and EMA. Collaborate with Clinical Development, Clinical Operations, Data Management, Regulatory Affairs, and Medical Writing teams. Review statistical outputs, including tables, listings, and figures (TLFs), to ensure accuracy and consistency with analysis plans. Apply appropriate statistical methodologies to address complex clinical trial design and analysis challenges. Contribute to clinical study reports (CSRs), integrated summaries of safety and efficacy, and other regulatory documents. Identify statistical risks and recommend appropriat

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Vanta
📍 United States• Full-time• Remote• $195K – $263K/yr
23 days ago

At Vanta, our mission is to help businesses earn and prove trust. We believe that security should be monitored and verified continuously, and we empower companies to practice better security and prove it with ease. Vanta has a kind and talented team, and while some have prior security experience, many have been successful at Vanta without it. The Risk pillar builds products that help customers understand and act on exposure across their organizations. Our work spans AI and data governance, privacy, identity and access, workforce security, enterprise risk management, and third-party oversight. These areas come together through Vanta's Trust Graph, which connects people, agents, data, controls, assets, and vendors to turn fragmented signals into clear context, prioritization, and action. As a Senior Fullstack Engineer, you'll lead product engineering work end to end across the stack, partnering closely with product and design to turn ambiguous customer problems into simple, high-quality experiences. This role offers a unique opportunity to shape a critical and rapidly growing area of Vanta's product. Depending on team priorities, you might build AI-powered workflows that let the Vanta Agent take on operational work, systems that transform connected signals into trustworthy recommendations, or intuitive experiences for complex internal and third-party programs. You'll tackle unique technical challenges and help customers move from manual, disconnected work to continuous, informed decision-making. Our business has achieved strong product-market fit and has monetized effectively since the day we signed our first customer. As Vanta continues to scale, engineers have meaningful opportunities to accelerate their growth and contribute directly to the company's next stage. What you'll do as a Senior Fullstack Engineer at Vanta: Identify, scope, and lead large technical projects, laying the groundwork for core products to evolve and scale into highly performant, reliable, and

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Okta
📍 San Francisco• Full-time• $264K – $363K/yr
2mo ago

Secure Every Identity, from AI to Human Identity is the key to unlocking the potential of AI. Okta secures AI by building the trusted, neutral infrastructure that enables organizations to safely embrace this new era. This work requires a relentless drive to solve complex challenges with real-world stakes. We are looking for builders and owners who operate with speed and urgency and execute with excellence. This is an opportunity to do career-defining work. We're all in on this mission. If you are too, let's talk. Position Overview: We are seeking a visionary Senior Director, Governance, Risk and Compliance (GRC) to lead and scale our world-class GRC Security organization. We don't view Governance, Risk, and Compliance (GRC) as a passive reporting function or an administrative checklist—we build engineering-forward, automated, and AI-driven GRC programs capable of operating in an evolving AI world. Reporting directly to Security Executive leadership, you will operate as a partner to the Senior Executives across Okta’s workforce, taking direct responsibility for cyber risk, data governance, security compliance and product certifications to enable Okta to ship world class, secure products. You will blend deep domain expertise across enterprise cyber risk, audit, and global compliance with a forward-thinking engineering mindset—pioneering continuous control monitoring, compliance-as-code, and robust AI governance for generative and agentic architectures. This is not just a leadership role. This is a builder’s role. Key Responsibilities: Drive AI-first Transformation: Execute a vision to integrate AI and agentic tools into daily GRC operations (automated evidence collection, automated risk scoring, intelligent policy mapping, and continuous audit readiness). Enterprise Risk & Governance: Operationalize Okta’s AI risk and governance framework—addressing training data protection, model risk management, responsible AI principles, and alignment with emerging

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Lyft
📍 United States• Full-time
3mo ago

At Lyft, our purpose is to serve and connect. We aim to achieve this by cultivating a work environment where all team members belong and have the opportunity to thrive. Data Science is at the heart of Lyft’s products and decision-making. Data Scientists at Lyft operate in dynamic environments, moving quickly to build the world’s best transportation solutions.We tackle a wide range of challenges - from shaping long-term business strategy with data, to making critical short-term decisions, to developing algorithms and models that power both internal systems and customer-facing products. Lyft Business builds products that help organizations move the people who matter most - employees, customers, patients, and guests - easily and efficiently. Our offerings include Business Travel, Lyft Pass, and Concierge (for healthcare and non-healthcare rides), enabling companies to manage transportation at scale through APIs, integrations (e.g., Concur, Expensify), and dedicated tools. These platforms power high-impact B2B use cases across corporate travel, healthcare access, customer experience, and community programs. We are seeking a Senior Data Scientist to lead technical initiatives across the entire Lyft Business product suite. In this role, you will shape the technical vision, define algorithmic roadmaps, and drive execution for data science projects that accelerate growth, improve operational efficiency, and deliver measurable value to our enterprise partners. You’ll collaborate closely with Product, Engineering, Design, and Go-to-Market teams to build production ML models, experimentation frameworks, and advanced analytics that inform strategy and power product innovation. This is a high-visibility, high-impact role with direct influence on Lyft’s enterprise offerings. The ideal candidate will bring deep expertise in algorithm development, machine learning, causal inference, and experimentation, alongside strong business acumen in B2B contexts and a proven track record of t

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3mo ago

At Lyft, our purpose is to serve and connect. We aim to achieve this by cultivating a work environment where all team members belong and have the opportunity to thrive. Data Science is at the heart of Lyft’s products and decision-making. Data Scientists at Lyft operate in dynamic environments, moving quickly to build the world’s best transportation solutions.We tackle a wide range of challenges - from shaping long-term business strategy with data, to making critical short-term decisions, to developing algorithms and models that power both internal systems and customer-facing products. Lyft Business builds products that help organizations move the people who matter most - employees, customers, patients, and guests - easily and efficiently. Our offerings include Business Travel, Lyft Pass, and Concierge (for healthcare and non-healthcare rides), enabling companies to manage transportation at scale through APIs, integrations (e.g., Concur, Expensify), and dedicated tools. These platforms power high-impact B2B use cases across corporate travel, healthcare access, customer experience, and community programs. We are seeking a Senior Data Scientist to lead technical initiatives across the entire Lyft Business product suite. In this role, you will shape the technical vision, define algorithmic roadmaps, and drive execution for data science projects that accelerate growth, improve operational efficiency, and deliver measurable value to our enterprise partners. You’ll collaborate closely with Product, Engineering, Design, and Go-to-Market teams to build production ML models, experimentation frameworks, and advanced analytics that inform strategy and power product innovation. This is a high-visibility, high-impact role with direct influence on Lyft’s enterprise offerings. The ideal candidate will bring deep expertise in algorithm development, machine learning, causal inference, and experimentation, alongside strong business acumen in B2B contexts and a proven track record of t

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About the Team At OpenAI, our User Safety & Risk Operations (USRO) team helps protect our products and users from abuse, fraud, safety risks, and other forms of misuse. We operate at the front line of real-world safety and risk management, translating user and operational signals into timely decisions, effective interventions, and improvements to our systems. This role sits on a new team within USRO focused on building operational capacity for new, ambiguous, or fast-moving areas of work. The team helps define what needs to be built, creates the operating model to support it, and works with partner teams to make the work scalable and durable over time. As a Strategic Operations Lead, you will focus on large, cross-functional initiatives that require clear thinking, technical fluency, strong execution, and the ability to bring structure to undefined problems. About the Role We are seeking a Strategic Operations Lead to drive new and existing strategic operating builds across User Safety & Risk Operations. This is a senior IC role for someone who can turn broad, undefined priorities into clear operating models, launch plans, requirements, stakeholder alignment, documentation, reporting, and execution rhythms. This role will often support initiatives where OpenAI is developing new products or partnerships and the operating model is still being defined. These programs have a direct user safety and risk nexus because new deployment models can change what signals OpenAI can see, who owns response decisions, and how user-impacting risks are detected, escalated, and resolved. You will clarify what OpenAI owns, what partner teams own, what signals we can reliably monitor, how issues should be escalated, and how the workflow should evolve from launch support into a durable operating model. The right person is highly strategic and deeply practical. They can move from executive-level framing to detailed workflow design, stakeholder management, SOPs, launch readiness, ri

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OpenAI
📍 San Francisco• Full-time• Remote• $234K – $260K/yr
15 days ago

About the Team OpenAI Finance helps ensure the organization is positioned for long-term success as we pursue our mission. The Strategic Sourcing & Procurement team enables OpenAI to scale responsibly, securely, and at speed by helping teams choose the right external partners, structure strong commercial agreements, and build resilient supplier ecosystems. We work at the intersection of innovation and execution, partnering closely with leaders across the company to turn rapidly evolving needs into scalable, compliant, and economically sound solutions. Professional services are a critical source of specialized expertise, capacity, and operational leverage across OpenAI. Our work spans consulting and advisory services, finance and accounting, legal, people and talent, managed services, Human Data services, and other enterprise capabilities. Done well, sourcing becomes a source of trust and momentum—helping teams move faster with the right partners, clearer outcomes, stronger economics, and appropriate safeguards. About the Role We are seeking a Strategic Sourcing Lead to own and execute OpenAI’s category strategy for Professional Services. This is an experienced individual-contributor role for a high-velocity, hands-on sourcing operator who can set category priorities, own complex work end to end, exercise sound judgment, influence senior stakeholders, and build scalable category mechanisms in a rapidly growing organization. You will turn incomplete information, shifting priorities, and unclear decision paths into practical next steps and disciplined execution. You will manage a broad portfolio of services engagements—from strategic advisory relationships and enterprise programs to high-volume statements of work. Partnering directly with leaders across Finance, Accounting, Legal, People, Extended Workforce, and business teams, you will set category priorities and translate needs into clear sourcing strategies, executable engagement models, and measurable outcomes.

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Coinbase
📍 Abu Dhabi• Remote• AED 730K – AED 730K/yr
17 days ago

Ready to do the most impactful work of your career? At Coinbase , we are uncompromising on our mission to increase economic freedom. The bar is high, the environment is intense, and we like it that way. This isn't a place for complacency, it’s a place to be pushed past your perceived limits. If you're ready to build the future of finance alongside people who refuse to settle for "good enough," you belong here. Coinbase is a remote-first, but not remote-only company. Expect to get together quarterly for intense in-person working sessions called “surges.” learn more about working at Coinbase . Coinbase is building its regulated presence in the Middle East, and this role sits at the center of that expansion. In this role, you'll drive Coinbase's regional crypto strategy, manage critical regulatory relationships, and build the operational foundation for our growing business. This is a rare opportunity to shape how crypto capital markets develop in one of the world's most strategically important financial centers. What You'll Do Build and lead the locally based Abu Dhabi team, managing Coinbase's Middle East crypto business and ADGM legal entity while engaging senior regulators, clients, and industry stakeholders Drive the development and execution of Coinbase's UAE crypto strategy in close collaboration with the Dubai/VARA team Develop operational capacity to grow Coinbase's tokenization business and adjacent opportunities under ADGM Oversee strategic budgeting and resourcing to optimize business impact and ensure alignment with local and global financial frameworks Establish robust governance structures, including controls, compliance programs, and ethical leadership practices that align local operations with global standards Lead ongoing engagement with ADGM and FSRA, cultivating trusted relationships with senior regulators and key external stakeholders Champion Coinbase's culture within the entity, ensuring customer interests are appropriately prioritized

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Mach Industries
📍 Huntington Beach• $125K – $175K/yr
18 days ago

About Mach Industries Founded in 2023, Mach Industries is a rapidly growing defense technology company focused on developing next-generation autonomous defense platforms. At the core of our mission is the commitment to delivering scalable, decentralized defense systems that enhance the strategic capabilities of the United States and its allies. With a workforce of approximately 350 employees, we operate with startup agility and ambition. Our vision is to redefine the future of warfare through cutting-edge manufacturing, innovation at speed, and unwavering focus on national security. We are dedicated to solving the next generation of warfare with lethal systems that deter kinetic conflict and protect global security. The Role We are seeking a knowledgeable and proactive Lead Environmental Health & Safety Engineer to provide technical leadership and hands-on execution of EHS programs across our engineering, manufacturing, prototyping, testing, and operational environments. This role will serve as a senior technical EHS resource, partnering directly with Engineering, Manufacturing, Operations, Facilities, and site leadership to identify hazards, evaluate risk, develop engineering and administrative controls, and ensure compliance with applicable environmental and occupational safety requirements. The Lead EHS Engineer will be highly engaged in day-to-day operations and is expected to spend significant time in manufacturing, laboratory, prototype, test, and other operational areas. The ideal candidate is comfortable operating in rapidly evolving environments where new equipment, processes, materials, and hazards are regularly introduced. The successful candidate will combine strong regulatory knowledge with an engineering mindset; focusing on eliminating or reducing hazards through design and practical risk controls rather than relying solely on procedures or administrative compliance. Key Responsibilities EHS Technical Leadership & Risk Management Serve as a te

Work Flexibility: Remote or Hybrid or Onsite Provides strategic leadership for portfolio and technology transformation across GQO & Corporate Functions, shaping an integrated agenda that advances enterprise priorities, standardization, and measurable business value across critical capabilities. Serves as a trusted advisor to senior business and technology leaders, aligning strategic priorities, informing investment decisions, and advancing high-impact initiatives across EDT, GQO, and Corporate Functions. Converts business strategy into a clear, multi-year transformation agenda that strengthens operating models, accelerates execution, and enhances enterprise performance. Essential duties & responsibilities: (detailed description) Enterprise Transformation Leadership: Help set the strategic direction for technology transformation and acceleration across GQO & Corporate Functions, translating enterprise priorities into an integrated portfolio of initiatives that enhance process effectiveness, scalability, standardization, and business performance. Technology Acceleration Office: Lead the Technology Acceleration Office as the portfolio engine that runs delivery and execution readiness. Manage multiple workstreams and deliver sequenced multi-quarter roadmaps with cross-initiative dependencies. Produce execution-ready initiatives including scope, value, ROM cost, risks, and decisions needed. Develop business cases with estimated value in performance, headcount impact, level of effort, and time to value. Portfolio Strategy, Governance, and Prioritization: Lead a disciplined portfolio management capability across strategic programs and investments. Establish governance, prioritization frameworks, sequencing, dependency management, resource alignment, and performance oversight to

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2mo ago

About the Team OpenAI Finance helps ensure the organization is positioned for long-term success as we pursue our mission. The Strategic Sourcing & Procurement team enables OpenAI to scale responsibly, securely, and at speed by helping teams choose the right external partners, structure strong commercial agreements, and build resilient supplier ecosystems. We work at the intersection of innovation and execution, partnering closely with leaders across the company to turn rapidly evolving needs into scalable, compliant, and economically sound solutions. Professional services are a critical source of specialized expertise, capacity, and operational leverage across OpenAI. Our work spans consulting and advisory services, finance and accounting, legal, people and talent, managed services, and other enterprise capabilities. Done well, sourcing becomes a source of trust and momentum—helping teams move faster with the right partners, clearer outcomes, stronger economics, and appropriate safeguards. About the Role We are seeking a Strategic Sourcing Lead to own and execute OpenAI’s category strategy for Professional Services. This is an experienced individual-contributor role for a high-velocity, hands-on sourcing operator who can set category priorities, own complex work end to end, exercise sound judgment, influence senior stakeholders, and build scalable category mechanisms in a rapidly growing organization. You will turn incomplete information, shifting priorities, and unclear decision paths into practical next steps and disciplined execution. You will manage a broad portfolio of services engagements—from strategic advisory relationships and enterprise programs to high-volume statements of work. Partnering directly with leaders across Finance, Accounting, Legal, People, Extended Workforce, and business teams, you will set category priorities and translate needs into clear sourcing strategies, executable engagement models, and measurable outcomes. You will operate inde

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Midjourney
📍 San Francisco• Full-time• $241K – $250K/yr
2mo ago

What you’ll do Act as the in-house electrical lead for Midjourney Medical: own the electrical architecture of the scanner and the technical direction for all board-level design. Own complex board design end-to-end: architecture, schematic capture, layout (high-speed digital, analog/mixed-signal, power), DFM/DFT, fabrication and assembly vendor management, bring-up, and revision control. Write firmware for embedded targets (MCU/SoC): drivers, real-time control loops, safety-relevant logic, bootloaders, and field update paths. Audit and update HDL (FPGA) code for high-throughput data acquisition, timing/synchronization, triggering, and pre-processing of ultrasound and sensor data streams. Define electrical interfaces and data contracts with software, recon/ML and mechanical teams: timing budgets, clocking/sync, signal integrity, connectors/harnessing, and failure modes. Establish electrical engineering rigor: design reviews, schematic/layout review checklists, bring-up procedures, test fixtures, and documentation suitable for a regulated medical device program (DHF, traceability, change control). Mentor and grow the electrical function; select and manage external design partners where leverage is high. What we’re looking for Deep experience designing complex boards from blank page to stable revision, including high-speed digital and analog/mixed-signal domains. Strong schematic and layout skills (Altium/KiCad or equivalent) with real signal integrity, power integrity, grounding, and EMI/EMC instincts. Solid embedded firmware background in C/C++ (and Python for tooling): peripherals, DMA, interrupts, real-time constraints, and debugging on hardware. Practical HDL experience (VHDL/Verilog/SystemVerilog) for data acquisition, timing, and streaming interfaces. Track record of owning bring-up and debug on real hardware: scopes, logic analyzers, and disciplined root-cause analysis. Technical leadership: clear trade-offs, strong written documentation, and the ability to set

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Upwork
📍 Toronto• Full-time• C$114K – C$164K/yr
Just now

Upwork Inc.’s (Nasdaq: UPWK) family of companies connects businesses with global, AI-enabled talent across every contingent work type including freelance, fractional, and payrolled. This portfolio includes the Upwork Marketplace, which connects businesses with on-demand access to highly skilled talent across the globe, and Lifted, which provides a purpose-built solution for enterprise organizations to source, contract, manage, and pay talent across the full spectrum of contingent work. From Fortune 100 enterprises to entrepreneurs, businesses rely on Upwork Inc. to find and hire expert talent, leverage AI-powered work solutions, and drive business transformation. With access to professionals spanning more than 10,000 skills across AI & machine learning, software development, sales & marketing, customer support, finance & accounting, and more, the Upwork family of companies enables businesses of all sizes to scale, innovate, and transform their workforces for the age of AI and beyond. Since its founding, Upwork Inc. has facilitated more than $30 billion in total transactions and services as it fulfills its purpose to create opportunity in every era of work. Learn more about the Upwork Marketplace at Upwork.com and follow us on LinkedIn, Facebook, Instagram, TikTok, and X; and learn more about Lifted at Go-Lifted and follow on LinkedIn. Lifecycle Marketing is a horizontal team that shapes how we engage clients and talent across the full journey, and this role sits in our demand-side acquisition lane. We’re hiring a Lifecycle Marketing Lead, Growth & Acquisition to own high-impact lifecycle programs that help close the new-client acquisition gap through smarter demand capture and stronger engagement with SMB audiences. You’ll lead key initiatives across outbound prospecting and always-on content, translate performance signals into clear recommendations, and help shape how lifecycle marketing contributes to Upwork’s 2026 priorities. This is a senior indi

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Snowflake
📍 Menlo Park• Full-time• $122K – $160.6K/yr
10 days ago

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. We are growing our Global Communications team and hiring a Public Relations Lead to help drive the narratives behind how Snowflake is shaping the future of enterprise AI. This role sits within Corporate Communications and focuses on some of our highest-impact storytelling: bringing customer proof points to life, supporting executive thought leadership, and building PR programs for Snowflake's emerging and growth markets. You will work across programs ranging from earnings and executive visibility to customer campaigns and international market launches, with real ownership, variety, and room to build. We are looking for someone who is equal parts strategist and executor, scrappy and organized, and energized by working at the intersection of corporate narrative and customer impact. AS A SNOWFLAKE PR LEAD, YOU WILL: Own and drive PR programs that amplify Snowflake's customer success, sourcing stories, building campaigns, and securing meaningful earned media coverage Support executive thought leadership programs for senior Snowflake leaders, translating company strategy into compelling external narratives Lead PR strategy and execution for Snowflake's emerging markets, including international media relations, agency management, and stakeholder coordination Develop and pitch pre

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