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Senior Lead Python Jobs

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Explore current senior lead python jobs. Use filters to narrow by work mode, employment type, experience and date posted.

G
GoCardless
📍 London• £99.2K – £148.8K/yr
9mo ago

About us GoCardless, a Mollie company, is a global leader in bank payments. Over 100,000 businesses, from start-ups to household names, use GoCardless to collect, manage and send bank payments through Direct Debit, real-time payments and open banking. With US$130bn+ processed annually across 30+ countries, we handle recurring and one-off payments without the chasing, stress, or expensive fees. Our end-to-end payment platform also features AI-powered solutions to improve payment success and reduce fraud, alongside connections to over 350 platforms businesses use everyday. We are headquartered in the UK, with teams and operations spanning North America, Europe and Asia-Pacific. For more information, please visit www.gocardless.com and follow us on LinkedIn @GoCardless. Mollie is the leading payments and financial services partner for business, rooted in Europe, with global reach. The role Data sits at the core of our mission. We leverage bank account data to deliver high-value, intelligent payment solutions for our customers, from enhancing payment success rates to driving payer fraud prevention. As a Senior Data Scientist within our Payment Intelligence team, you’ll partner with Software Engineers, Product Managers, and Designers to turn big ideas into reality. You’ll own the full lifecycle of our algorithms, shaping everything from the initial concept to production-ready code that powers our global payment network. At GoCardless, our stack is centered around Google Cloud Platform and Vertex AI, providing a high-performance environment for innovation. Our Data Scientists operate at the intersection of Python, SQL, and BigQuery to build and deploy high-performance models at scale. What you’ll do Lead the end-to-end delivery of models at scale, from initial discovery and feature engineering to production, A/B testing and continuous monitoring. Collaborate with product and engineering peers to turn complex data into real-time, mission-critical fraud prevention sol

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About Formation Bio Formation Bio is a tech and AI driven pharma company differentiated by radically more efficient drug development. Advancements in AI and drug discovery are creating more candidate drugs than the industry can progress because of the high cost and time of clinical trials. Recognizing that this development bottleneck may ultimately limit the number of new medicines that can reach patients, Formation Bio, founded in 2016 as TrialSpark Inc., has built technology platforms, processes, and capabilities to accelerate all aspects of drug development and clinical trials. Formation Bio partners, acquires, or in-licenses drugs from pharma companies, research organizations, and biotechs to develop programs past clinical proof of concept and beyond, ultimately helping to bring new medicines to patients. The company is backed by investors across pharma and tech, including a16z, Sequoia, Sanofi, Thrive Capital, John Doerr, Spark Capital, SV Angel Growth, and others. You can read more at the following links: Our Vision for AI in Pharma Our Current Drug Portfolio Our Technology & Platform At Formation Bio, our values are the driving force behind our mission to revolutionize the pharma industry. Every team and individual at the company shares these same values, and every team and individual plays a key part in our mission to bring new treatments to patients faster and more efficiently. About the Position As a Senior Data Scientist - Medical Imaging at Formation Bio, you will lead our efforts to integrate advanced imaging analytics and AI into our drug development pipeline. In this role, you'll pioneer the application of computer vision and deep learning to medical imaging data (MRI, X-ray, CT, PET) to accelerate clinical trials and improve patient outcomes. You'll develop state-of-the-art models for automated image analysis, disease progression monitoring, and treatment response assessment. Working closely with clinical teams, radiologists, and dru

pythonai
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PG
9mo ago

Why Sony Interactive Entertainment? Sony Interactive Entertainment isn’t just the Best Place to Play — it’s also the Best Place to Work. Sony Interactive Entertainment (SIE) is the company behind the PlayStation brand. As a subsidiary of Sony Group Corporation, we’re part of a proud legacy of innovation and excellence. SIE is a dynamic technology company, delivering cutting-edge hardware and network services to more than 100 million people and an entertainment leader, home to some of the most beloved and recognizable intellectual properties (IP) in the world. Our role at SIE is to create and nurture the experiences under the PlayStation brand, a name synonymous with entertainment excellence and creativity. Senior Data Scientist - Experimentation & Measurement San Mateo, CA Overview: As a Senior Data Scientist on the Decision Science team within the Data Science, Analytics, & Enablement (DSAE) organization at PlayStation, you will take a leading role in designing and interpreting experiments that evaluate the impact of PS4 to PS5 user migration initiatives, growth marketing strategies, and broader campaign performance. This role is focused on advancing our experimentation practices—bringing statistical rigor, clear measurement strategies, and deep causal inference expertise to some of the most critical initiatives across PlayStation. What You’ll Be Doing: Lead the design, execution, and interpretation of A/B tests and quasi-experiments to evaluate the impact of user migration initiatives (PS4 to PS5), growth marketing strategies, and campaign performance. Partner with cross-functional teams (product, engineering, marketing) to embed experimentation into development and iteration cycles. Serve as a thought leader on best practices for hypothesis development, metric selection, test structure, and results communication. Apply advanced causal inference methods when experimentation isn’t feasible or to inform test design and prior

pythonsqlmachine learning
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O
9mo ago

Who We Are At OKX, we believe that the future will be reshaped by crypto, and ultimately contribute to every individual's freedom. OKX is a leading crypto exchange, and the developer of OKX Wallet, giving millions access to crypto trading and decentralized crypto applications (dApps). OKX is also a trusted brand by hundreds of large institutions seeking access to crypto markets. We are safe and reliable, backed by our Proof of Reserves. Across our multiple offices globally, we are united by our core principles: We Before Me , Do the Right Thing , and Get Things Done . These shared values drive our culture, shape our processes, and foster a friendly, rewarding, and diverse environment for every OK-er. About the Opportunity: The Sr Data Scientist, Risk will offer a strategic perspective, deep analytical and modeling capabilities, and a collaborative working style. The right candidate will have strong intellectual curiosity and passion for achieving business results. An ability to quickly define the problem, research and leverage state-of-the-art modeling techniques, and provide timely recommendations will be essential. Key skills will include a strong analytical mindset, deep understanding of most popular machine learning algorithms and lead key initiatives with integrity and a passion for investigations, problem solving, and troubleshooting. What You’ll Be Doing : Identify complex fraud patterns and their technical root causes through detailed data mining and analysis, including identification of sophisticated fraud methods employed by actors who are deliberately trying to avoid detection. Serve as technical SME by sharing new data mining techniques, maintaining technical reference documentation, and interfacing with partner technology teams. Collaborate across business and technology stakeholders to communicate analytical findings to both technical and non-technical audiences. Provide technical guidance for engineering projects that incorporate

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C
10mo ago

Responsibilities: Annotate Case Report Form (acrf.pdf) following FDA/CDISC or sponsor guidelines. Develop SDTM specifications and generate SDTM datasets using SAS. Develop ADaM specifications and generate ADaM datasets using SAS based on Statistical Analysis Plan. Develop Tables, Listings, Graphs, Patient Profile in support of the Clinical Study Report, Posters, Manuscripts. Develop ADaM data, Tables, Listings, Figures for Integrated Summary of Safety (ISS) and Integrated Summary of Efficacy (ISE). Create electronic submission package to FDA, e.g., define.xml or define.pdf following FDA guidelines with minimum supervision. Proficient in analyze information and develop innovative solutions to programming and data analysis challenges; Support the point of contact (POC) of programming with statisticians for statistical input and analysis interpretation Follow and reinforce regulatory agency requirements during daily job. Serve as a programming team lead and contribute to department initiative. Provide guidance, mentoring, training for team members and help solve issues from cross-functional teams. Review draft and final production deliverables for project to ensure quality and consistency. Skills and Qualifications: Bachelor’s/Master’s degree in Statistics, Mathematics, Computer Science, Electrical Engineering, Biotechnology or related scientific disciplines. Minimum of 4+ years of clinical programming experience, along with 1+ year of project management and 1+ year of people management experience. Proven knowledge and training in high level computing languages such as. SAS, C/C++, Java, R, Python, MATLAB and SQL. Database programming experience is a plus. Proficient in decoding programming logic and assembling programming code based on logic provided and be able to explain to team members. Proficient in applying concepts in Artificial Intelligence and Machine Learning in the real world. In-depth knowledge of ICH, Good Clinical Practices, Clinical research, Clini

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C
10mo ago

Responsibilities: Annotate Case Report Form (acrf.pdf) following FDA/CDISC or sponsor guidelines. Develop SDTM specifications and generate SDTM datasets using SAS; Develop ADaM,specifications and generate ADaM datasets using SAS based on Statistical Analysis Plan; Develop Tables, Listings, Graphs, Patient Profile in support of the Clinical Study Report, Posters, Manuscripts; Develop ADaM data, Tables, Listings, Figures for Integrated Summary of Safety (ISS) and Integrated Summary of Efficacy (ISE) Create electronic submission packages to FDA, e.g., define.xml or define.pdf following FDA guidelines with no supervision. Expert-level in analyze information and develop innovative solutions to programming and data analysis challenges; Serve as point of contact (POC) of programming with statisticians for statistical input and analysis interpretation; Follow and reinforce regulatory agency requirements during daily job. Serve as a programming team lead and contribute to department initiatives. Provide guidance, mentoring, training for team members and help solve issues from cross-functional teams; Review draft and final production deliverables for project to ensure quality and consistency. Work with global team or sponsors to coordinate project deliverables, timelines and resources. Skills and Responsibilities: Bachelor’s/Master’s degree in Statistics, Mathematics, Computer Science, Electrical Engineering, Biotechnology or related scientific disciplines with 5+years of clinical programming experience. Proven knowledge and training in high level computing languages such as. SAS, C/C++, Java, R, Python, MATLAB and SQL. Database programming experience is a plus. Expert-level in decoding programming logic and assembling programming code based on logic provided and be able to explain to team members. Expert level in applying concept in Artificial Intelligence and Machine Learning in real world. In-depth knowledge of ICH, Good Clinical Practices, Clinical research, Clinical tria

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R
Roblox
📍 San Mateo• Full-time• $243.3K – $295.3K/yr
10mo ago

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. As a member of the Infrastructure Foundation Hardware Engineering team, you will play a key role in enabling our mission to deliver a reliable, high-performing, and cost-efficient infrastructure that powers the world’s play. In this specialized role, you will be the technical lead for our GPU and AI accelerator ecosystem. You will be responsible for the full lifecycle of GPU hardware, from initial architectural evaluation and firmware qualification to large-scale fleet integration and performance tuning. You will ensure that Roblox’s massive-scale rendering and ML workloads run on the most optimized and stable hardware possible. You Will: Architect & Prototype: Prototype next-generation GPU-accelerated hardware platforms, ensuring seamless integration between high-density compute nodes, high-speed interconnects (NVLink/PCIe Gen5/6), and system firmware. GPU Optimization: Drive the integration, performance testing, and debugging of GPUs in our fleet, focusing specifically on hardware-level optimizations, driver tuning, and thermal/power management. Validation & Certification: Develop and execute rigorous evaluation and stress-testing strategies for GPU-heavy server platforms to ensur

pythonlinuxai
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B
Bazaarvoice
📍 Belfast• Full-time• Hybrid
10mo ago

At Bazaarvoice, we create smart shopping experiences. Through our expansive global network, product-passionate community & enterprise technology, we connect thousands of brands and retailers with billions of consumers. Our solutions enable brands to connect with consumers and collect valuable user-generated content, at an unprecedented scale. This content achieves global reach by leveraging our extensive and ever-expanding retail, social & search syndication network. And we make it easy for brands & retailers to gain valuable business insights from real-time consumer feedback with intuitive tools and dashboards. The result is smarter shopping: loyal customers, increased sales, and improved products. The problem we are trying to solve : Brands and retailers struggle to make real connections with consumers. It's a challenge to deliver trustworthy and inspiring content in the moments that matter most during the discovery and purchase cycle. The result? Time and money spent on content that doesn't attract new consumers, convert them, or earn their long-term loyalty. Our brand promise : closing the gap between brands and consumers. Founded in 2005, Bazaarvoice is headquartered in Austin, Texas with offices in North America, Europe, Asia and Australia. It’s official: Bazaarvoice is a Great Place to Work in the US , Australia, India, Lithuania, France, Germany and the UK! As the Lead Engineer of Portal Reports and Insights application team, your primary responsibilities will include designing and implementing distributed, fault-tolerant systems and creating high performance Reporting and Insights applications for Bazaarvoice clients that can run nearly 10k reports every week. These reports and insights are used to produce various metrics about Bazaarvoice products and programs so that their performance can be measured. Reports can also be used to simply export raw data about client's UGC like questions, answers, reviews and products, while Insights provides an

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Who is Artefact? Artefact is a next-generation strategy and data consulting firm dedicated to transforming organizations through data and AI. We combine the rigor of top-tier strategy consulting with deep expertise in data, digital, and analytics to help clients achieve tangible business impact. With 1,800+ consultants, data scientists, and engineers across 23 countries, we work with global leaders such as Samsung, L’Oréal, Orange, and Sanofi. Our Romandie office (Geneva/Lausanne) is at the heart of Artefact’s growth, advising clients on their most pressing strategic challenges — from AI strategy and governance to digital transformation roadmaps and new business model design. Main Responsibilities As a Senior Technical Consultant / Senior AI Engineer , you will lead the design and delivery of impactful AI and data solutions. You’ll combine hands-on engineering with client advisory, guiding multi-disciplinary teams from opportunity framing to production deployment. Own solution architecture & delivery: Define end-to-end architectures (data, ML/LLM, APIs, security), make build/buy decisions, and drive projects from PoC to production with reliability, observability, and cost in mind. Lead complex PoCs & pilots: Scope, prototype, and validate AI/ML use cases (incl. LLMs/GenAI, RAG, fine-tuning, evaluation) and convert successful pilots into scalable products. Advanced programming & modeling: Build, adapt, and evaluate ML/DL/LLM models using Python (PyTorch, TensorFlow, HuggingFace, LangChain/LlamaIndex), including prompt engineering, fine-tuning/LoRA, vector search, and safety/guardrails. Cloud & MLOps/LLMOps: Design and operate solutions on Azure, GCP, or AWS (CI/CD, containers, model serving, feature stores, vector DBs, monitoring, eval pipelines). Client advisory & stakeholder management: Translate business goals into technical roadmaps, present to senior stakeholders, manage risks and trade-offs, and ensure measurable business impact. Quality, se

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TA
Together AI
📍 San Francisco• $200K – $280K/yr
11mo ago

About the Role Together AI is building the AI Acceleration Cloud, an end-to-end platform for the full generative AI lifecycle, combining the fastest LLM inference engine with state-of-the-art AI cloud infrastructure. The AI Infrastructure team at Together AI is at the forefront of building and scaling the foundational systems that power our generative AI platform. The storage and observability team is crucial for designing, implementing, and maintaining robust distributed storage solutions, ensuring seamless data access and management. They are also responsible for developing comprehensive observability platforms, providing critical insights into system performance and GPU utilization, and proactively identifying and resolving issues. Responsibilities Design and implement a scalable observability platform (metrics, logs, traces) using tools like Prometheus, Grafana, ClickHouse, ClickStack, and OpenTelemetry, including telemetry data pipelines and log aggregation workflows. Develop automated monitoring, alerting, and anomaly detection systems, including SLIs/SLOs, runbooks, and predictive analytics for critical services. Build and deploy custom observability tools and infrastructure-as-code using Go, Python, Terraform, Ansible, and Helm. Collaborate with engineering teams to enhance distributed tracing and application monitoring, and lead incident response with post-mortem analysis. Define observability best practices. Requirements Expertise in observability platforms (Prometheus, Grafana, ClickStack, OpenTelemetry) and cloud-native monitoring services (AWS, GCP, Azure). Strong programming skills in Go, Python, or similar languages, with proficiency in infrastructure-as-code tools (Terraform, Ansible, Helm). Experience designing, operating, and scaling large-scale distributed systems and pipelines for high-volume data ingestion and real-time querying. Deep understanding of containerization (Docker) and orchestration (Kubernetes). Knowledge of microservices architectu

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Location Details: India, Remote At GoDaddy, the future of work varies by team. Some teams are fully office-based. Others split their time between remote work and the office. Some teams work completely from home. This is a remote position, so you’ll be working remotely from your home. You may occasionally visit a GoDaddy office to meet with your team for events or meetings. Join Our Team... At GoDaddy, we are seeking a Senior Analyst to join our Assurance, Risk and Compliance (ARC) Enablement team. This role will help transform how our team and business improve processes, use technology, and empower people to manage risk and build the future compliance program. Reporting directly to the Director of ARC, you will drive meaningful improvements in people, processes, and technology. You will redesign workflows that cause unnecessary manual effort. You will develop automation and analytics that make compliance ongoing instead of occasional. You will ensure the team and collaborators are prepared to maintain and expand what is developed. You will work with SOX, Internal Audit (IA), and Enterprise Risk Management (ERM) to deliver scalable, auditable, and AI-forward solutions. If improving how compliance functions motivates you, this is your role! What you'll get to do... Find the friction and fix it. Map current-state workflows across ARC's SOX, IA, and ERM functions. Identify where manual effort and inefficiency exist. Lead process improvements that remove them for good. Build automation that actually sticks — develop pipelines, CI/CD-enabled code repositories, and repeatable testing frameworks that turn periodic compliance efforts into continuous, always-on operations. Make compliance visible in real time — build Power BI dashboards and analytics pipelines (Python, SQL) that give leadership and control owners a live view of risk posture. Put Jira to work for compliance — configure workflows, automation rules, and intake forms that embed traceability and standardization di

pythonsqlaws
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A
Affirm
📍 Poland• Full-time• Remote• $384K – $576K/yr
13mo ago

At Affirm, we exist for the moments that matter—giving people a clear, predictable way to pay over time, with no hidden fees, no surprises, and no tradeoffs on what matters most. Join the pioneering Servicing International team at the forefront of Affirm's global expansion, building the foundational platform to launch our products into a new generation of international markets. This role will focus specifically on purchase protection, including disputes and refunds—a critical part of the user journey and an area of significant investment—to ensure trust and satisfaction for our newest customers. Success requires deep collaboration, and you will partner closely with European engineering counterparts and engineers across our global Servicing Engineering organization to build cohesive, scalable solutions. If you are passionate about creating world-class user experiences and excited by the challenge of launching products in new regions, join us. Help build the next generation of Affirm's platform and define our presence around the world. What you’ll do You will be responsible for owning and delivering quarterly goals for your team, leading engineers on your team through ambiguity to solve open-ended problems, and ensuring that everyone is supported throughout delivery. You will support your peers and stakeholders in the product development lifecycle by collaborating with product management, design & analytics by participating in ideation, articulating technical constraints, and partnering on decisions that properly consider risks and trade-offs. You will proactively identify project, process, technology or business issues, advocate for them, and lead in solving them. You will support the operations and availability of your team’s artifacts by creating and monitoring metrics, escalating when needed, and supporting “keep the lights on” & on-call efforts. You will foster a culture of quality and ownership on your team by setting or improving code review and design

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A
Affirm
📍 Spain• Full-time• Remote• €86K – €122K/yr
13mo ago

At Affirm, we exist for the moments that matter—giving people a clear, predictable way to pay over time, with no hidden fees, no surprises, and no tradeoffs on what matters most. Join the pioneering Servicing International team at the forefront of Affirm's global expansion, building the foundational platform to launch our products into a new generation of international markets. This role will focus specifically on purchase protection, including disputes and refunds—a critical part of the user journey and an area of significant investment—to ensure trust and satisfaction for our newest customers. Success requires deep collaboration, and you will partner closely with European engineering counterparts and engineers across our global Servicing Engineering organization to build cohesive, scalable solutions. If you are passionate about creating world-class user experiences and excited by the challenge of launching products in new regions, join us. Help build the next generation of Affirm's platform and define our presence around the world. What you’ll do You will be responsible for owning and delivering quarterly goals for your team, leading engineers on your team through ambiguity to solve open-ended problems, and ensuring that everyone is supported throughout delivery. You will support your peers and stakeholders in the product development lifecycle by collaborating with product management, design & analytics by participating in ideation, articulating technical constraints, and partnering on decisions that properly consider risks and trade-offs. You will proactively identify project, process, technology or business issues, advocate for them, and lead in solving them. You will support the operations and availability of your team’s artifacts by creating and monitoring metrics, escalating when needed, and supporting “keep the lights on” & on-call efforts. You will foster a culture of quality and ownership on your team by setting or improving code review and design

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I
13mo ago

Why us? Insurify is one of the America’s fastest-growing MIT FinTech startups and has been recognized as one of Inc. 5,000’s fastest-growing private companies in America in 2025, 2024, 2023, 2022 and 2021, Forbes Fintech 50 List for 2023, 2022, and 2021, Forbes Next Billion Dollar Startups of 2022 global and Top 100 InsurTech company. We’re changing the way millions of people compare, buy and manage insurance with artificial intelligence, technology, and superior product design. Our company vision is to be recognized as the preeminent and most trusted digital agent for insurance comparison, purchase, and management. Our team is critical to achieving our vision and fostering the right culture is essential to our team’s success. How you will make an impact: Lead cross-functional projects from ideation to execution with a high degree of independence and maximum impact Solve high velocity, high impact analytics problems Scale the business using data Work on a mix of analytics engineering, business analytics, and data science using SQL and Python Build scalable data infrastructure that solves real problems Sample projects: Operate and improve a data product to serve evolving business needs Refactor data system to scale with increased volume and new requirements Build new data pipelines to support tracking of new business initiatives Champion usage of new tools and systems to improve team processes Improve the prediction accuracy of our customer acquisition machine-learning bidding algorithms Perform customer segmentation analysis to discover where to improve Insurify products Improve alerting systems to help us triage data quality issues at scale Key Skills + Background 3-4 years of experience, record of impact and success in a similar role (Analytics or Data Engineering, Data Science, Data Analysis) Expertise in and real-world experience with SQL Exposure to data warehousing and ETL concepts Strong quantitative and programming skil

pythonsqlartificial intelligence
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R
Reddit
📍 United States• Remote• $190.8K – $267.1K/yr
14mo ago

Reddit is a community of communities. It’s built on shared interests, passion, and trust, and is home to the most open and authentic conversations on the internet. Every day, Reddit users submit, vote, and comment on the topics they care most about. With 100,000+ active communities and approximately 130 million daily active unique visitors, Reddit is one of the internet’s largest sources of information. For more information, visit www.redditinc.com . Reddit has a flexible workforce! If you happen to live close to one of our physical office locations our doors are open for you to come into the office as often as you'd like. Don't live near one of our offices? No worries: You can apply to work remotely in any country in which we have a physical presence. Role Description: This is a Generalist Senior Backend Engineer position within the Ads Organization. Ads is the fuel that powers Reddit’s mission. As a backend engineer on the team, candidates might work on: Microservices and APIs that power our advertiser-facing product, ads.reddit.com Distributed systems that ensure the right ad gets shown to the right user at the right time Backends that power interactive user experiences on our ads like Polls and Games Real time, data intensive systems that measure the performance of our ad campaigns Infrastructure that supports all of the above Technologies used on the team include: Languages: Go, Python, Scala Frameworks: Spark, Thrift, Baseplate, Kafka Datastores: Postgres, BigQuery, Redis, Druid Tools: Kubernetes, Argo, Docker Responsibilities: Work with product managers to design and implement Ads products. Collaborate closely with the platform and data teams while building new features. Lead the processes needed to improve operational stability, including improving code quality, delivering dashboards and data visualizations. Build extensible components that would align with the product objectives. Support day to day project management tasks including commun

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