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Senior Lead Python Jobs

10,000 active opportunities · Updated for October 2026

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Explore current senior lead python jobs. Use filters to narrow by work mode, employment type, experience and date posted.

T
Twilio
📍 - US• Full-time• Remote• $106.3K – $132.9K/yr
1mo ago

Who we are At Twilio, we’re shaping the future of communications, all from the comfort of our homes. We deliver innovative solutions to hundreds of thousands of businesses and empower millions of developers worldwide to craft personalized customer experiences. Our dedication to remote-first work , and strong culture of connection and global inclusion means that no matter your location, you’re part of a vibrant team with diverse experiences making a global impact each day. As we continue to revolutionize how the world interacts, we’re acquiring new skills and experiences that make work feel truly rewarding. Your career at Twilio is in your hands. . Hiring and how we work We use Artificial Intelligence (AI) to help make our hiring process efficient. That said, every hiring decision is made by real Twilions! Also, while we are a remote-first company, you may be asked to report in person on an ad-hoc basis for team gatherings, functional off-sites or customer meetings. . See yourself at Twilio Join the team as Twilio’s next Senior Executive Business Partner. About the job This position is needed to proactive calendar support, juggling multiple deliverables with competing deadlines and take effective action without knowing the full picture. You will partner with executives to drive execution on team initiatives in support of business priorities. You will serve as a point person for both your executives direct reports and the administrative business partners in your organization. Responsibilities In this role, you’ll: Handle end to end meeting coordination and facilitation, plan team building activities, leadership summits and offsites Partner with your execs to understand their priorities, stack rank meeting requests and redirect as needed, work independently and make decisions on behalf of your executive. Act as a point person for your executives’ direct reports and team, build strong cross functional relationships and maintain team morale.

REMOTErestaigo
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T
Twilio
📍 - Canada• Full-time• Remote• From $99.8K/yr
1mo ago

Who we are At Twilio, we’re shaping the future of communications, all from the comfort of our homes. We deliver innovative solutions to hundreds of thousands of businesses and empower millions of developers worldwide to craft personalized customer experiences. Our dedication to remote-first work , and strong culture of connection and global inclusion means that no matter your location, you’re part of a vibrant team with diverse experiences making a global impact each day. As we continue to revolutionize how the world interacts, we’re acquiring new skills and experiences that make work feel truly rewarding. Your career at Twilio is in your hands. . Hiring and how we work We use Artificial Intelligence (AI) to help make our hiring process efficient. That said, every hiring decision is made by real Twilions! Also, while we are a remote-first company, you may be asked to report in person on an ad-hoc basis for team gatherings, functional off-sites or customer meetings. . See yourself at Twilio Join the team as Twilio’s next Senior AI and Data Specialist About the job This position will be responsible for unlocking exceptional growth for Twilio’s customers and business. We are seeking a high-achieving individual to join Twilio’s Strategy & Operations team within the Industry Relations & Strategic Growth organization. In this high-visibility role, you will use data analysis, scripting, and agentic workflows to improve product quality, fight fraud, reduce billing errors, and optimize gross margins for our global telecommunications network. You will build root-cause-analysis tools and automations that query complex datasets, uncover trends, drive human decisions, and allow business partners to self-serve data insights. To achieve this, you will collaborate closely with Carrier Relations to define business requirements, engage with Enterprise Technology and Engineering to build data pipelines and governance, and partner with Produc

REMOTEpythonsqlrest
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T
Twilio
📍 - US• Full-time• Remote• $106.3K – $132.9K/yr
1mo ago

Who we are At Twilio, we’re shaping the future of communications, all from the comfort of our homes. We deliver innovative solutions to hundreds of thousands of businesses and empower millions of developers worldwide to craft personalized customer experiences. Our dedication to remote-first work , and strong culture of connection and global inclusion means that no matter your location, you’re part of a vibrant team with diverse experiences making a global impact each day. As we continue to revolutionize how the world interacts, we’re acquiring new skills and experiences that make work feel truly rewarding. Your career at Twilio is in your hands. . Hiring and how we work We use Artificial Intelligence (AI) to help make our hiring process efficient. That said, every hiring decision is made by real Twilions! Also, while we are a remote-first company, you may be asked to report in person on an ad-hoc basis for team gatherings, functional off-sites or customer meetings. . See yourself at Twilio Join the team as Twilio’s next Senior AI and Data Specialist About the job This position will be responsible for unlocking exceptional growth for Twilio’s customers and business. We are seeking a high-achieving individual to join Twilio’s Strategy & Operations team within the Industry Relations & Strategic Growth organization. In this high-visibility role, you will use data analysis, scripting, and agentic workflows to improve product quality, fight fraud, reduce billing errors, and optimize gross margins for our global telecommunications network. You will build root-cause-analysis tools and automations that query complex datasets, uncover trends, drive human decisions, and allow business partners to self-serve data insights. To achieve this, you will collaborate closely with Carrier Relations to define business requirements, engage with Enterprise Technology and Engineering to build data pipelines and governance, and partner with Produc

REMOTEpythonsqlrest
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S
1mo ago

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Senior Software Engineer - External Observability Platform Location: Bellevue, WA (Hybrid: 3 days/week in-office) Team: Infrastructure & Observability Platform Engineering About the Role Snowflake’s Data Cloud processes exabytes of data across multi-cloud global environments every day. Delivering seamless reliability and real-time visibility to thousands of global enterprise customers requires an Observability Platform built on hyper-scalable backend distributed systems. We are seeking a Senior Software Engineer to own key components of our AI native External Observability Platform . In this role, you will contribute to the technical road map for customer-facing telemetry, system metrics, audit logs, distributed tracing, and actionable operational insights. You will build high-throughput, low-latency infrastructure capable of ingesting, processing, and serving petabytes of telemetry data with strict SLA guarantees. You will join a team of world-class engineers in our Bellevue, WA office. To be successful, you must be deeply technical, capable of leading complex technical projects, and skilled at collaborating with the brightest technical minds in the industry. Key Responsibilities Develop and Scale Distributed Infrastructure: Design and implement key components of Snowf

javavueaws
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PE
Private Employer
📍 New York• Full-time• Hybrid• $66.2K – $99.2K/yr
1mo ago

The Editorial team provides our customers with premium, differentiated visuals across news, sports, and entertainment that cover real people, events, actions, and facts. We also grow and maintain one of the world’s most extensive archives of socially significant, historical photos, footage, and prints. Getty Images is hiring a Senior Editor to join the Sport Editorial team in New York. Who You Are: As Senior Sports Editor, you will guide our Sport editing team in delivering exceptional results across live sporting events and client projects. Your role will be a blend of remote, in office and onsite work, including event support, team leadership during group edits, and ensuring timely global content distribution. Working in a fast-paced, deadline-oriented environment, you will balance editorial excellence with customer satisfaction. You’ll be integral to our global strategy, leading editing teams supporting events on an international scale. You should bring a deep understanding of both domestic and international sports, combined with experience in efficiently editing large volumes of content while meeting client expectations. Expertise in digital photography, photo editing, metadata management, and technical troubleshooting across PC and MAC platforms will be key to success in this role

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Glance
📍 San Mateo• $224.5K – $264.5K/yr
1mo ago

Glance Glance is an intelligent shopping agent, redefining the commerce experience. Powered by proprietary agentic intelligence and generative AI, Glance delivers a hyper-personalized consumer experience across mobile and TV — shaping the new era of shopping. Glance is operated by Glance InMobi Pte. Ltd., a non-consolidated subsidiary of global technology leader InMobi, and is backed by Mithril Capital, Google and Jio Platforms. To learn more, visit glance.com. InMobi InMobi Group is a global technology company shaping the future of agentic commerce and advertising. Through its ecosystem of businesses — including InMobi Advertising and flagship consumer platform Glance — InMobi leverages data, machine learning, and generative AI to help brands reach audiences more precisely and consumers discover products more intuitively. Glance, which is pioneering new models of agentic commerce, is owned and operated by Glance InMobi Pte. Ltd., a non-consolidated subsidiary of InMobi Pte. Ltd. InMobi Advertising InMobi Advertising, part of global technology company InMobi, is an agentic advertising platform helping brands and merchants achieve their business outcomes. Through its proprietary intelligence, AI-led solutions, and vast consumer reach — including flagship consumer platform Glance — InMobi Advertising delivers the omnichannel performance defining what's next in advertising and commerce. Glance is owned and operated by Glance InMobi Pte. Ltd., a non-consolidated subsidiary of InMobi Pte. Ltd. To learn more, visit advertising.inmobi.com. Overview of the Role: Glance is at an inflection point. With over 250 million daily active users and a platform embedded at the heart of the Android ecosystem, we're not building for scale...we're already there. Now, we're looking for a Senior Program Manager to join our Growth team and help us turn that scale into new markets, new partners, and new revenue. This is not a conventional program management role. You won't just track t

machine learningai
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About Us At Cloudflare, we are on a mission to help build a better Internet. Today the company runs one of the world’s largest networks that powers millions of websites and other Internet properties for customers ranging from individual bloggers to SMBs to Fortune 500 companies. Cloudflare protects and accelerates any Internet application online without adding hardware, installing software, or changing a line of code. Internet properties powered by Cloudflare all have web traffic routed through its intelligent global network, which gets smarter with every request. As a result, they see significant improvement in performance and a decrease in spam and other attacks. Cloudflare was named to Entrepreneur Magazine’s Top Company Cultures list and ranked among the World’s Most Innovative Companies by Fast Company. At Cloudflare, we’re not looking for people who wait for a polished roadmap; we’re looking for the builders who see the cracks in the Internet that everyone else has simply learned to live with. We value candidates who have the instinct to spot a "normalized" problem and the AI-native curiosity to create a solution using the latest tools. Our culture is built on iteration, leveraging AI to ship faster today to make it better tomorrow, while ensuring that every improvement, no matter how small, is shared across the team to lift everyone up. If you’re the type of person who values curiosity over bureaucracy, and that AI is a partner in solving tough problems to keep the Internet moving forward, you’ll fit right in. Available Locations: Southern California or Arizona *This is a work-from-home 100% remote role, but you should reside in one of the regions." What you’ll do as a Senior Customer Engineer SLED About the Role At Cloudflare , we are on a mission to help build a better Internet. As the architectural complexity of enterprise solutions scales, we are evolving how we partner with our customers. The Customer Engineer (CE) represents the core driver of our

javascriptpythonai
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A
Airbnb
📍 United States• Full-time• Remote
1mo ago

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: Airbnb’s mission is to create a world where anyone can belong anywhere. Airbnb Payments team supports this mission by economically empowering Airbnb businesses and our global community of guests and hosts. Airbnb Payments team allows any two people in the world to frictionlessly exchange money with easy to use payments services. It is a core strategy to fulfill Airbnb’s belongs anywhere mission.We are building a world-class payments platform that moves billions of dollars, in 191 countries, with 75 currencies, through a complex ecosystem of payments partners. We build and maintain our own in-house global payments platform because no solution exists with the global reach needed. As the platform grows we’ll be adding new payment partners, global licenses, compliance and regulation controls, and building new payment experiences for our guests and hosts. Payments Transactions team and Payments Payouts team are part of the core platform of the Airbnb Payments ecosystem. The teams are building the core billing system and payouts system for Airbnb money movements. The team engineers are responsible for the seamless orchestration and recording of Airbnb’s payment obligations with our community. They initiate, advance, and realize Airbnb’s payment commitments with our community in a way that is reliable, accurate, timely, scalable, and auditable. The Difference You Will Make: We are looking for talented and self-motivated Senior Software Engineers who are passionate about working in this highly dynamic domain and collaborating with world-class XFN teams to advance our mission. As part

REMOTEreactai
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B
1mo ago

About Us At BGBx , we're driven by a simple idea: breakthrough thinking creates breakthrough impact. As an independent commercial solutions partner to pharmaceutical and life science companies, we bring together strategists, scientists, communicators, creatives, technologists, and data experts to tackle some of healthcare's most important challenges. Our teams work across consulting and communications to help clients shape strategy, launch innovations, engage stakeholders, and drive meaningful results throughout the product lifecycle. The work is complex, fast-moving, and deeply connected to improving lives, creating opportunities for curious minds to make a real difference every day. If you're energized by collaboration, inspired by innovation, and motivated by work that matters, you'll find a place to grow, contribute, and make a meaningful impact at BGBx. Position Overview The Senior Medical Director, Medical Strategy & Scientific Affairs is responsible for leading the strategic direction and hands-on creation of high-quality medical and scientific content across multiple therapeutic areas. This role holds overall accountability for the medical and scientific integrity of both ongoing medical education programs and new business proposals. The Senior Medical Director will work on high-profile and strategic projects, with significant visibility both within the company and with clients. This position involves frequent interactions with clients and internal teams, ensuring alignment and effective communication. The Senior Medical Director will manage a team that includes Associate Medical Directors, Medical Writers, and Medical Interns, while also serving as a key liaison across various departments. The role requires the development of strong professional relationships with key customers and active participation in the creation of new service offerings that address the evolving needs of Evolution’s pharmaceutica

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Observe by Snowflake is an AI-powered observability platform built on the Snowflake AI Data Cloud and engineered for scale. We ingest and store logs, metrics, traces, and events on an open, scalable data lakehouse using open formats like Apache Iceberg — at dramatically lower cost. A dynamic Context Graph and chat-based AI SRE provide rich context and automated workflows so teams can move from detection to root cause and resolution 10x faster. Leading engineering teams at companies like Capital One, Topgolf, and Dialpad rely on Observe to troubleshoot hundreds of terabytes of telemetry daily while maintaining reliability at enterprise scale. As part of Snowflake, Observe combines startup-style ownership and velocity with the global reach, operational excellence, and ecosystem of one of the world's leading data platforms. We are hiring a Senior Software Engineer for Observe by Snowflake on the Data Management team. This team is responsible for the tables, views, and materialized views at the core of Observe's architecture. Observe's data lake approach lets customers correlate heterogeneous telemetry — logs, metrics, traces, events — across a unified data model. This role owns that data model: how customers define, shape, and query the semi-structured data that makes cross-si

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