Senior Sr Software Engineer Backend Jobs

Job Title: Principal Software Engineer Location: South San Francisco, CA preferred; Remote optional Job Type: Full-time About the Role We're seeking a Principal Software Engineer to join Natera's R&D team. We build the cloud infrastructure, workflow platforms, and data platforms that R&D uses to do its science - including a Kubernetes-based workflow execution platform, a custom R&D LIMS system, and a set of supporting tools that routinely handle production-scale workloads. This is a senior technical role. You'll own the full architecture, implementation, and delivery of large projects across our platform. You'll partner with the team lead on roadmap and tough technical calls, mentor mid-level engineers, and help the team find the right solution for the problem - not the most elaborate one. We're a small team (4 engineers + lead) with broad scope, and we're heavily AI-augmented: every engineer uses Claude Code / Cursor as a daily tool, and we build our own AI tooling (custom plugins, MCP servers, agents) to multiply ourselves. Responsibilities Architecture & Delivery: Own the design, implementation, and delivery of major initiatives across our platform. Take fuzzy problems through to shipped, working software used in production. Technical Leadership: Lead architecture and design reviews. Help the team find the right solution for the problem and avoid unnecessary complexity. Influence technical decisions across the team. Mentorship: Mentor mid-level engineers through code review, design docs, and pairing. Raise the engineering bar by example. AI-Native Development: Build and improve our AI-coding tooling alongside the rest of the team. Help us push the frontier of agent-driven software development inside the company. Cross-Functional Partnership: Work with bioinformaticians, scientists, and other R&D engineers to understand their needs and translate them into platform capabilities. Partner with the team lead on roadmap, prioritization, and tough te

POSITION SUMMARY: We are looking for a highly motivated Senior Research Associate with a strong focus on process optimization and improvements to join the Molecular Biology product development team, joining a group of scientists who are tasked with developing and advancing Natera’s oncology product portfolio. The Senior Research Associate performs research and/or development tasks in collaboration with others. Makes detailed observations, analyzes data, and interprets results. Investigates creates and develops new methods and technologies for project advancement. Maintains a high level of professional expertise through familiarity with scientific literature. PRIMARY RESPONSIBILITIES: Design, plan, and perform experiments geared towards the development of non-invasive prenatal tests and cancer detection tests. Autonomously and accurately plan and execute complex laboratory experiments Analyze data using advanced analytical tools Keep a detailed laboratory notebook; write protocols and experimental plans, and document results and scientific interpretations Contribute insight toward experimental findings and troubleshoot laboratory processes and protocols Communicate and discuss results with a multidisciplinary team including biologists, bioinformaticians, statisticians, software engineers, and managers Summarize work in research reports and laboratory meeting presentations Learn and understand the science behind ongoing research projects while simultaneously completing increasingly complex tasks. This role will have occasional access to PHI both in paper and electronic form and have occasional access to various technologies to access PHI (paper and electronic) in order to perform the job. The employee must complete training relating to HIPAA/PHI privacy, General Policies and Procedure Compliance training and security training as soon as possible but not later than the first 30 days of hire. Must maintain a current st

RDQ426R193 At Databricks, we are passionate about enabling data teams to solve the world's toughest problems — from making the next mode of transportation a reality to accelerating the development of medical breakthroughs. We do this by building and running the world's best data and AI infrastructure platform so our customers can use deep data insights to improve their business. Search plays a foundational role in this mission. Whether through keyword-based retrieval, semantic similarity via vector embeddings, or hybrid approaches that combine both, our Search technologies help customers find, discover, and understand information across massive, complex datasets. These capabilities power everything from Retrieval Augmented Generation (RAG), AI assistants, and recommendation systems to enterprise knowledge management, in-product search, and data exploration. As a Senior Engineering Manager for Search, you’ll play a critical role in building and scaling our next-generation Search product — spanning Vector Search, Keyword Search, and Search Quality. You’ll drive the design and evolution of a highly-performant, cost-efficient, and developer-friendly Search stack that enables customers to build AI applications with accuracy, speed, and scale. Beyond hands-on contributions, you’ll help define the long-term vision, mentor senior engineers, collaborate across teams, and lead strategic efforts that expand the technical and business impact of Search at Databricks. Check out our recent blog post: Decoupled by Design: Billion-Scale AI Search The impact you will have: Lead a team of talented software engineers to design, build, and operate the next-generation cloud-native Search services. Drive innovation across Vector Search, Keyword Search, and Hybrid Search capabilities to improve relevance, latency, and cost efficiency. Build a strong partnership with product and research teams to define the roadmap for Search Quality, including ranking models and evaluation frameworks. Mana

S r. Security Engineer - IAM Truveta provides unprecedented real-world data and real-time intelligence, powered by a dataset built with and owned by US health systems united in a mission of Saving Lives with Data. Together, we power breakthrough medical discoveries, accelerate regulatory-grade evidence, and improve patient care. Today, Truveta enables research on more than 130 million de-identified patients across the US. Achieving Truveta’s ambitious mission requires an incredible team of talented and inspired people with a special combination of health, software and big data experience who share our company values . This job requires daily onsite work at our headquarters in Hyderabad . Who We Need Truveta is rapidly building a talented and diverse team to tackle complex health and technical challenges. Beyond core capabilities, we are seeking problem solvers, passionate and collaborative teammates, and those willing to roll up their sleeves while making a difference. If you are interested in the opportunity to pursue purposeful work, join a mission-driven team, and build a rewarding career while having fun, Truveta may be the perfect fit for you. If you are interested in the opportunity to pursue purposeful work, join a mission-driven team, and build a rewarding career while having fun, Truveta may be the perfect fit for you. This Opportunity Success in the healthcare industry is predicated on a foundation of trust. We demonstrate our trustworthiness as stewards of health data through three foundational pillars: security, privacy, and compliance. The successful candidate will design , implement, and support solutions that support the company’s Digital Workplace strategy. The

JOB ROLE : SENIOR MANAGER, SOFTWARE ENGINEERING Location: Hyderabad, India (Hybrid) Department: Product Development ABOUT GHX GHX (Global Healthcare Exchange) is a leading healthcare technology company on a mission to simplify the business of healthcare and improve patient outcomes. Founded in 2000, GHX has built the world's largest cloud-based supply chain community connecting healthcare providers, suppliers, distributors, and partners to automate processes, reduce costs, and increase operational efficiency. GHX continues to innovate with intelligent automation and AI-driven capabilities across its product portfolio. ABOUT THE ROLE GHX is seeking a Senior Engineering Manager to lead a multi-disciplinary engineering team that powers intelligent, AI-augmented automation across multiple product lines with document understanding — extracting structured meaning from unstructured documents and data — as one of its core technical problems. This team spans three areas: a platform engineering team (AI, DevOps, Infra, architecture, business continuity, security etc.), a set of product-line delivery teams (each building product-specific business logic, validation, and integrations), and a team building the Human-in-the-Loop (HiTL) application along with reporting/analytics capabilities. You will lead through team leads or senior engineers rather than running delivery for a single team directly. You will set technical direction for shared platform capabilities that every product-line team depends on, while ensuring each product line independently meets its own functionality, quality, and delivery commitments. You will work directly with business, product, and operations stakeholders across every product line this platform serves, and you will own end-to-end outcomes: people, technical direction, and customer impact across the full teams. RESPONSIBILITIES Organizational & Engineering Leadership: • Lead and develop a multi-disciplinary team spanning platform engineering, pro

Zscaler (NASDAQ: ZS) accelerates digital transformation so customers can be more agile, efficient, resilient, and secure. The Zscaler Zero Trust Exchange platform protects thousands of customers from cyberattacks and data loss by securely connecting users, devices, and applications in any location. Distributed across 200+ public data centers globally and thousands of private sites at the edge, the SASE-based Zero Trust Exchange is the world’s largest in-line cloud security platform. We believe the future of work is Human + AI and are building an AI-native enterprise where human potential is amplified by machine intelligence to solve the world’s hardest security challenges. Driven by deep customer obsession, we are committed to the mission, outcome, and to each other. We bring these commitments to life through three core behaviors: ownership and collaboration, trust through outcomes and impact, and a challenge culture with ongoing feedback. Ready to make an impact at the company pioneering security transformation in the AI era? Join us at Zscaler. Role We are looking for a Sr. Manager of Software Engineering to join our team. This is a hybrid role, reporting to the Director, Engineering in the Zero Trust Exchange department. The Sr. Manager will oversee Identity and Access control infrastructure while leading a dynamic team advancing Zero Trust technology and flagship cloud security products. In this role, you will manage end-to-end development and quality, collaborating globally with architects, product managers, developers, and engineers to ensure successful production delivery. What you’ll do (Role Expectations) Promote the product vision internally and externally as the representative of the company, product, and team at all levels Collaborate with product management to develop roadmaps, identify gaps, and implement changes for improved outcomes Design solutions and implement with cloud reliability, availability, scalability, and security in mind Wor

Opportunity Overview: We are seeking a Senior Engineering Manager to lead our Review Engineering team — roughly 20+ engineers across three squads in the US and India — building the workflows and capabilities that let clinical operations staff deliver care at scale, efficiently and with high quality. Leading through dedicated technical leads on each squad, you'll own the reliability and technical direction of Review's systems while partnering closely with Product, Design, Security, Clinical Operations, and peer engineering teams on shared platforms. This is an opportunity to shape a growing, business-critical part of Cohere's platform and to grow the next generation of engineering leaders in health technology. This is a remote-first role that may require travel to Boston, MA for new hire onboarding and occasional in-person team meetings and company events. What you’ll do: Lead 20+ engineers across multiple agile squads (US and India) through dedicated technical leads Own production reliability for Review-owned systems — incident response, root-cause RCAs, and cross-functional tiger teams for major incidents Set technical vision and provide leadership across design and sprint processes, partnering with Staff Engineers Drive delivery transparency through sprint metrics, catching risk early and informing data-driven interventions Partner with Product, Design, Security, Clinical Ops, and peer engineering teams (including our Hyderabad group) on shared systems and initiatives Own hiring, leveling, and career growth for direct reports and their leads; help attract and retain top talent Build a culture that grows early-career engineers into future health-tech leaders, with a bias toward team autonomy Champion testing, quality, and security practices in a regulated (HIPAA/SOC2) environment What you’ll need: 5+ years managing software engineering teams in a fast-paced, agile environment, including 3+ years leading multiple teams through technical leads or managers Exper

As a Sr. Staff Technical Program Manager, you will partner with key Engineering, Product, Product Design, Marketing, and Analytics stakeholders to conduct data-driven experiments and deliver features for MongoDB. As a seasoned program leader, you will be responsible for one of our most mission-critical programs this fiscal year, and own executive level communication related to the program. We are looking to speak to candidates who are based in Dublin or Cork for our hybrid working model, or remote within Ireland. The right candidate for this role will be: Experienced with 15+ years of working in an engineering organization leading complex cross-functional technical programs Experienced with 10 years of Software development background, with Cloud storage and compute products Experience with Service Oriented Architecture and Cloud Infrastructure Able to leverage their knowledge and experience to influence technical discussions, summarizing outcomes and next steps Skilled at communicating across a diverse set of engineers and stakeholders Hyper-organized and capable of coordinating across multiple independent work streams and organizations A role model for effective execution practices, driven by an attuned sense of priority and urgency Able to leverage their experience in program delivery to influence improvements to our tools, operations, and architecture Trained in working with project tracking software (e.g. Jira, Rally, MS Project) Familiar with MongoDB or a comparable technology Interested in business automation work such as scripting in Python, Google Apps Script and Slack Position Expectations: Leverage technical acumen and analytical skills to drive engineering programs forward and maximize business value delivery Recognize patterns in a sea of information and take action accordingly Design, maintain, and improve the processes and tools that power program delivery Build strategic partnerships with Product and Engineering stakeholders Expand knowledge into new

GAQ427R209 We're looking for a Senior Recruiter with experience driving recruitment in the EMEA region for our Field Engineering & Forward Deployed Engineering teams, to help us identify and hire great people for Databricks as we continue our expansion. You will conceive practical and creative ways to identify leading talent and invest considerable time activating and engaging passive candidates. You will use data to set benchmarks and metrics to create targeted recruiting strategies while partnering with leadership to build inspired teams. You will report directly to the Manager, EMEA Talent Acquisition. This is a fixed-term position for a period of 12 months, with the possibility of extension. The impact you will have: Apply your knowledge to meet our hiring needs within Field Engineering and develop unique full-cycle hiring strategies. Build engaged talent pipelines for roles across Field Engineering, with active and passive candidates which can sustain long-term hiring goals. Act as a trusted advisor to Field Engineering leaders across EMEA — running intake and calibration sessions, challenging assumptions on role design and seniority, and holding hiring managers to a consistently high bar. Create closing approaches to manage partner expectations through market data Lead the business with data to promote future workforce planning decisions and accurate forecasting Help Databricks to provide a positive interview experience for all and periodically review experiential data to enhance our offering and drive Diversity and Inclusion in our hiring What we look for: Experience with recruiting for Go To Market professionals, specifically Pre-sales Engineers and Post-sales engineers from Entry level to Director within the software industry. Experience building strategic partnerships within the business and cross-functionally, and influencing senior stakeholders with data rather than opinion. Experience recruiting across multiple EMEA markets and navigating the

About Syllo Syllo is on a mission to transform litigation. Our product is a unified litigation platform that enables lawyers and paralegals to safely harness the power of language models and agentic AI throughout the litigation life cycle. Since going to market, we have gained a diverse group of enterprise customers, including some of the biggest law firms and corporations in the country, and we are quickly expanding. By reducing the expense of litigation industry-wide, we aim to improve access to high-quality representation and promote the alignment of legal outcomes with merit. About the Role We’re looking for a Sr. Engineering Manager who will foster a collaborative, high-performing environment where engineers can grow, learn, and thrive. Responsibilities Mentor, coach, and support the career growth of 8-10 engineers. You will conduct regular 1-on-1s, provide actionable feedback, and foster a culture of ownership and psychological safety. Participate in personnel review, including the shaping of the performance review process and structure. Improve engineering processes (scrum meetings, code reviews, testing) to increase velocity without sacrificing quality. Partner with Product Managers to translate roadmaps and designs into concrete execution plans. Be responsible for allocating work among engineers, monitoring progress, and facilitating collaboration. Work with the leadership team to define engineering staffing strategy and team structure, and participate in hiring and recruiting. Qualifications 5+ years of experience in engineering management, leading teams of 5 or more in a fast-paced environment, preferably remote. Core software engineering skills, including proficiency in languages such as Python and Ruby. Knowledge of engineering practices and patterns for the full software development lifecycle. Comfortable with ambiguity and shifting pr

Everpure (NYSE: P) has evolved from storage pioneer to data platform, closing fiscal 2026 with $3.7 billion in revenue, its first billion-dollar quarter, and accelerating growth into FY27. Our strategic agenda spans the companies defining the next era of technology - hyperscalers, AI labs, the AI hardware supply chain, data platform providers, and the broader AI ecosystem. This type of work—work that changes the world—is what the tech industry was founded on. So, if you're ready to seize the endless opportunities and leave your mark, come join us. THE ROLE As a Senior SSD Firmware Architect, you will be the visionary behind the intelligence of our proprietary DirectFlash™ technology, fundamentally decoupling storage software from commodity hardware limitations. You will architect high-performance firmware that harmonizes custom controller SoCs with NAND media to deliver unprecedented density and reliability for enterprise and hyperscale environments. By leading the technical strategy between hardware, silicon vendors, and systems teams, you ensure our storage modules don't just store data—they redefine how the world accesses it. WHAT YOU'LL DO Define and drive the firmware architecture for next-generation DirectFlash™ SSD modules, including subsystem design, firmware modularization, and system integration. Work with controller vendors and hardware teams to bring up new SSD controller SoCs and enable features such as PCIe, NAND interfaces, power-loss protection, and telemetry. Develop firmware components supporting NVMe and OCP SSD specifications, ensuring compliance, performance, and interoperability. Debug complex cross-layer issues involving firmware, controller hardware, NAND media, and host systems. Improve SSD data path performance and latency through firmware design and analysis. Review designs, mentor engineers, and improve development tools, testing, and automation. We are primarily an in-office environment and therefore, you will be expected to work from th

The Sr. Technical Program Manager for Robot Platform on PMO is a seasoned program management expert and cross-functional leader that will be responsible for strategic planning and execution of technical and integrated product milestones for our vehicle platforms on our path to launch. This person will work closely with hardware, firmware, software, safety, operations, manufacturing and systems integration teams to structure, plan, and execute milestones to achieve our company goals. The right candidate will have experience with complex HW/SW systems engineering and integration, and with leading large, cross-functional teams to deliver ambitious programs. In this role, you will: Partner with a wide range of department managers to translate the top-down corporate strategy and milestones into detailed technical roadmaps, timelines, and deliverables Influence key decisions working cross-functionally across engineering, manufacturing, product, operations, and strategy to reach the right outcomes Establish standard reports to provide concise and effective communications to key stakeholders on program status, issues/risks, and accomplishments Define and develop new KPIs and other methods to measure performance that best translate progress toward goals Ensure the program goals are aligned with business objectives; build and sustain momentum among cross-functional TPMs and workstreams towards delivering on time and on target Maintain a strong technical understanding of our vehicle platforms, software lifecycle, safety clearance process, and test operations Qualications: BS or MS degree in an engineering discipline or equivalent experience 7+ years of experience in engineering, program management, or management consulting with a focus on product launches Success in driving complex SW/HW integration processes and optimizations and leading complex cross-functional programs end to end

Replit is the agentic software creation platform that enables anyone to build applications using natural language. With millions of users worldwide, Replit is democratizing software development by removing traditional barriers to application creation. Replit is seeking a Senior Business Development Manager to lead and scale our outbound sales development team as we expand our go-to-market efforts. This role will oversee a team of BDRs (Business Development Representatives) proactively targeting and engaging high-potential accounts to build a robust pipeline for our Account Executives. The ideal candidate will have hands-on outbound prospecting experience and proven leadership skills, a strong understanding of the modern GTM technology, previous experience in creating systems and orchestrating technology to support an efficient & scalable 0->1 outbound workflow, and previous experience collaborating tightly with marketing and sales ops to build highly-targeted account lists and multi-channel outreach sequences. Experience & interest in vibe coding and/or technical experience is highly valued. This position is critical to our go-to-market strategy, responsible for defining our outbound playbook, identifying key target personas , hiring top-tier talent, coaching team members, and ensuring persistent, high-quality outreach & pipeline generation across all segments from SMB to Enterprise. You'll establish the foundation for scalable revenue growth while architecting a personalized first-touch experience that sets the tone for their Replit journey. We believe this role offers a distinctive opportunity for proven sales development professionals who excel in both strategic account targeting and team leadership, with a passion for technology and AI. You'll leverage your expertise to build a world-class BDR organization that effectively cuts through the noise to communicate Replit's value proposition: a world where anyone can create software using natural langu

Who We Are Addepar is a global data and AI platform empowering investment professionals to turn complex financial information into actionable intelligence. Addepar unifies portfolio, market and client data in a total portfolio view and delivers AI-powered insights within investment and client workflows. More than 1,500 firms in 60 countries use Addepar to manage and advise on nearly $10 trillion in assets. Its open platform integrates with 650 software, data and consulting partners to power end-to-end investment operations across firms of all sizes and levels of complexity. Addepar supports clients worldwide with offices in New York City, Salt Lake City, São Paulo, London, Edinburgh, Geneva, Warsaw, Dubai, Pune and Singapore. The Role We are currently seeking a Client Success Strategy and Operations Senior Analyst. Addepar is looking for a driven and adaptable professional to join our Client Success Strategy & Operations team. In this role, you'll help define and optimize how our Client Success and Services organization operates. You'll develop recommendations and solutions that bridge the gap between our client success vision and the people, processes, and systems that deliver on it day to day. You'll work cross-functionally across CS, Services, Sales, and R&D to drive alignment and ensure our clients are set up for long-term success. This is a dynamic role ideal for someone looking to combine strategic thinking with hands-on operational execution in a high-growth SaaS environment. Applicants must be legally authorized to work in the United States for any employer without requiring current or future visa sponsorship (for example, employment-based visas such as H-1B , F-1 /OPT, or similar), and must be authorized to begin work in the U.S. on their first day of employment. What You'll Do Bring analytical rigor and creative problem-solving to Client Success operations, developing strategies and operational frameworks to improve health scoring, net revenu

POSITION SUMMARY: The Product Development Sr. Research Associate will contribute to the design, execution and participation in experiments/tasks to support oncology product development and verification and validation (V&V) studies under design control, for next generation sequencing (NGS) assays. We are looking for a meticulous and dedicated candidate with direct laboratory experience in assay development who can work effectively in a fast-paced environment to ensure the highest quality clinical assays are developed and launched for our patients. The ideal candidate will be an enthusiastic and driven professional who is eager to learn, flexible, enjoys multi-tasking and possesses strong wet lab skills. PRIMARY RESPONSIBILITIES : With some supervision, design and execute low to moderate complexity experimental workflows, including cfDNA extraction, library preparation for next-generation sequencing (NGS) using both manual and automated platforms, employing various molecular biology and standard laboratory methods in accordance with standard operating procedures (SOPs) and work instructions Assist with the design, plan and execution of experiments to support the development and V&V of oncology assays Maintain a detailed and organized electronic laboratory notebooks and accurate records of lab work using a variety of software including Google Sheets, Microsoft Excel, and internal databases Analyze and interpret experimental data using appropriate statistical and analytical tools Assist in drafting documentation including study protocols, reports, SOPs and work instructions Coordinate across multiple internal teams to ensure the timely execution of the studies. Adapt to handle multiple tasks and priorities, and perform other duties as assigned Learn the science behind ongoing research projects while actively completing increasingly complex tasks QUALIFICATIONS : Bachelor’s degree in molecular biology, genetics, biochemistry or related field with a minimum