Jobs in United States

Ai Oncology Portfolio Lead in United States

5,082 active opportunities · Updated October 2026

Explore current ai oncology portfolio lead jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

M
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

From $151K/yr

Quick readStrong listing-quality and freshness signals

Join the MongoDB Server Query Execution team, and help us build a world-class distributed open-source database. Our team plays a crucial role in the performance and efficiency of MongoDB's data processing. We are responsible for building and improving the core execution engine that powers all queries, taking a logical query plan produced by the optimizer and turning it into reality. This includes developing the physical operators for data retrieval and manipulation, improving the runtime for complex analytical and transactional workloads, and owning critical components such as our new execution engine. In addition to the core server, we support the query execution needs of other major products like Atlas Streams, Atlas Search and Vector Search, and mongosync, making our work vital to the entire MongoDB ecosystem. You will be joining a globally distributed team with a significant presence in both North America and Europe. While this role is based in the NAMER region, you will regularly collaborate closely with colleagues across different time zones. We support both office-based work in our North America hubs like New York, as well as remote work. We have tons of interesting problems to solve with a direct impact on users for transactional, time-series, and analytical workloads. To meet the ever-increasing data demands of modern applications, we are actively evolving our query system; this includes strategically re-architecting and improving key components of our query execution engine. We need your help to design and build the core of a distributed, flexible schema document database. This role can be based out of one of our North America offices, such as NYC or Palo Alto, or remotely across North America. Candidate Profile 10+ years of hands-on, professional experience in query engine development or database internals Experience with building production-level code with a large user base, robust design structure and rigorous code quality Degree in Computer Science or

MongoDBAWSAzureRest
M
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

From $1.3M/yr

Quick readStrong listing-quality and freshness signals

The Opportunity MongoDB’s partner ecosystem — systems integrators, ISVs, and the major cloud providers — is a strategic growth engine for the business. We’re looking for a Senior Manager, Sales Plays and Offerings to design the joint go-to-market motions that turn partner relationships into pipeline and revenue. This is a highly cross-functional, strategic role: you’ll build the sales plays and joint offerings themselves, partner with Enablement to get the field and our partners ready to sell them, instrument how they perform, and work with the Programs lead to make sure incentives reward the behavior we want to see. You will report directly to the VP of Partner Strategic Operations and act as a connective layer between Partnerships, Sales, Enablement, and Programs — translating ecosystem strategy into repeatable, measurable, field-ready motions. We are looking to speak to candidates who are based anywhere in the US for our hybrid working model. What You'll Do Build sales plays and joint offerings Design and package partner sales plays and joint solution offerings with priority ISVs, SIs, and cloud partners — defining the joint value proposition, target segment, competitive positioning, and playbook for how field and partner sellers execute it Partner with Product Marketing, Solutions Engineering, and partner counterparts to validate technical integration stories and translate them into a compelling, sellable narrative Prioritize which plays to build and scale based on market opportunity, partner readiness, and alignment to MongoDB’s strategic pillars (e.g., AI, migrations, industry verticals) Own the lifecycle of each play from concept through launch, iteration, and eventual retirement or refresh Drive partner and field enablement Partner closely with the Enablement team to translate each sales play into field- and partner-facing assets: pitch decks, battlecards, demo scripts, certification conte

MongoDBAWSAzureGCP
D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -85.2%

From $192K/yr

Quick readStrong listing-quality and freshness signals

As the Engineering Manager for Commercial Audit, you will lead a high-performing team responsible for scaling Datadog’s security and compliance posture through automation, tooling, and engineering excellence. Our GRC (Governance, Risk, and Compliance) function is a critical partner to the broader Security and Engineering organizations, ensuring that Datadog not only meets rigorous global regulatory standards but does so in a way that is efficient, scalable, and integrated into our cloud-native infrastructure. You will manage a team of engineers and analysts who are transitioning to a GRC engineering direction to treat compliance as a software problem, leveraging AI, custom tooling, CI/CD pipelines, and cloud-native services to turn complex regulatory requirements into actionable, automated controls. You will lead the strategy, roadmap, and execution of Datadog’s Commercial Audit initiatives. This is a high-impact leadership role where you will grow a team of engineers and analysts responsible for directly maintaining our compliance programs and related audits (e.g., SOC2, PCI, HIPAA, ISO) while looking to improve efficiency and effectiveness through platforms and tooling. You will act as a bridge between technical engineering, legal, and compliance, enabling the organization to move fast while maintaining a secure and compliant environment. You will champion a culture of "compliance-as-code," identifying opportunities to automate evidence collection, streamline control testing, and reduce manual toil for both your team and our partner engineering teams. At Datadog, we place value in our office culture - the relationships and collaboration it builds, and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Lead the strategy, roadmap, and execution of Datadog’s commercial security compliance efforts, shifting from manual audit processes to automated, scalable

PythonAWSAzureGCP
M
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

From $104K/yr

Quick readStrong listing-quality and freshness signals

MongoDB is hiring a Staff Product Marketing Manager to build and own our go-to-market narrative for the Public Sector vertical, with a focus on Federal Government and the broader public sector market. This is a foundational hire for MongoDB’s Industry Verticals product marketing function: you will define how MongoDB’s unified data platform, spanning cloud, on-premises, and hybrid database deployments with integrated, production-ready AI capabilities, shows up for government buyers. You’ll turn a major compliance milestone into a durable competitive differentiator: developing the positioning, messaging, and sales-ready content that helps government agencies, systems integrators, and cloud/public-sector resellers understand why MongoDB is the right data platform for mission-critical, regulated workloads. You do not need prior government or public-sector work experience to succeed in this role — you need to be an excellent product marketer who can get fluent in a new domain quickly and partner closely with the compliance, product, and sales experts who already are. This role can be based in one of our MongoDB hub offices in the U.S. or remotely in the U.S. What you’ll do Own positioning and messaging for MongoDB’s Public Sector go-to-market, leading the federal GTM and launch related activities Translate MongoDB’s data platform capabilities — document database, search, vector search, stream processing, and integrated AI — into mission-relevant outcomes and value propositions for government buyers and the systems integrators who serve them Partner with Compliance, Security, Industry Solutions and Product teams to accurately represent related certification requirements in external-facing content, staying current as MongoDB pursues additional authorizations (e.g., DoD Impact Levels) Build the public sector sales enablement toolkit: battlecards, pitch decks, discovery guides, ROI/value models, and competitive intelligence tailored to federal buying processes and procuremen

MongoDBAWSAzureAI
D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -85.2%

From $192K/yr

Quick readStrong listing-quality and freshness signals

As Engineering Manager for Threat Detection, you will lead a high-performing team that powers Datadog's detection program. Threat Detection is the organization responsible for keeping Datadog ahead of an evolving threat environment: closing coverage gaps faster, raising the bar on signal quality, and shipping detections that hold up under the scale and complexity of cloud-native infrastructure. Your team will combine direct detection expertise, platform engineering, and applied AI to ship detections at a pace and scale traditional rule-writing alone cannot match. Examples of what your team will work on include detection-authoring agents, the detection platform that powers every rule in production, coverage analysis, alert triage and response automation, and the evaluation infrastructure that holds these systems to a high bar of fidelity. Detection authorship is a shared responsibility across the organization, and your team will contribute both by building the systems that scale our authoring capacity and by writing detections directly when their domain expertise is the right tool. You will partner closely with our Security Incident & Response Team (SIRT), Cyber Threat Intelligence (CTI), AI Engineering teams, and Datadog's broader Security organization. This is a high-impact leadership role: you will grow a team of security and software engineers responsible for building and executing our detection and AI strategy. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Lead the strategy, roadmap, and execution of Datadog Security's shift to AI-accelerated detection and response. Drive development of high-fidelity detections as a shared responsibility across the organization, ensuring your team's systems and direct contributions raise the bar on coverage and

PythonCI/CDRestAI
M
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

From $151K/yr

Quick readStrong listing-quality and freshness signals

MongoDB’s Security Product Management team is seeking a Staff Product Manager to own security, compliance, and public sector product strategy within Atlas for Government (A4G). In this role, you will be a key member of the security product management team, helping make data security a market differentiator that enables MongoDB to win in enterprise and regulated industries. You will lead product strategy and execution for capabilities and programs that support federal compliance requirements and broader regulated-industry needs. You will work across Engineering, Compliance, Legal, Security, and Go-to-Market teams to translate complex regulatory and customer requirements into clear product investments, roadmaps, and outcomes. This role is suited for a candidate who can orchestrate multiple interlinked product areas, own cross-team product and architectural trade-offs, and align senior stakeholders around multi-year bets. You will be expected to identify opportunities and dependencies that cut across team boundaries, bring clarity to ambiguous problem spaces, and establish reusable ways of working that help MongoDB deliver secure, compliant platform capabilities for public sector and other regulated markets. You will partner closely with senior engineering and business leaders to evaluate trade-offs, sequence investments, and bring clarity to decisions that balance customer impact, execution risk, and long-term business value. This role can be based out of of our offices or remotely in the United States. The Federal Risk and Authorization Management Program (FedRAMP) is a US government-wide program that provides a standardized approach to security assessment, authorization, and continuous monitoring for cloud products and services. Our FedRAMP program requires that anyone who is accessing customer data or metadata inside the Authorization Boundary be a US Person on US Soil. Responsibilities Security and Compliance Product Strategy Own the public sector compliance roadm

MongoDBAWSAzureGCP
M
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

From $151K/yr

Quick readStrong listing-quality and freshness signals

The Role MongoDB is seeking a Staff Product Manager to lead strategic initiatives across Identity and Security. In this role, you will serve as the senior product leader shaping the next generation of authentication, authorization, and access control across MongoDB Atlas, the core database engine, and emerging developer platforms. You will lead the strategy for non-human identity—spanning workload identity federation, zero-trust passwordless access, Model Context Protocol (MCP) integrations, and autonomous AI agentic identity. You will partner closely with engineering, UX, product marketing, and enterprise customers to build identity experiences that are enterprise-grade, seamless for developers, and secure by default. Responsibilities Set and champion a multi-year product strategy across interrelated identity areas, aligning dependencies and investments to MongoDB’s broader objectives Identify cross-cutting customer and market opportunities, build business cases for investment, and bring a clear point of view to senior stakeholders Lead workload identity federation and programmatic access initiatives across cloud and enterprise identity environments Define secure authorization approaches for AI agents and MCP clients, including delegation, identity lifecycle, policy, and administrative controls Drive developer-first access management, ensuring security controls enhance rather than obstruct developer velocity Partner with engineering, design, GTM, and cross-functional leadership to validate enterprise requirements, prioritize initiatives, and measure feature adoption Stay ahead of evolving cloud security paradigms, emerging standards (e.g., SPIFFE/SPIRE, O4AA), and AI access patterns to guide executive decision-making Represent MongoDB’s security and identity vision at industry events, customer advisory boards, and executive briefings Demonstrate creativity, an innovative spirit, and a bias towards action Requirements 8+ years (or equivalent experience) in Pro

MongoDBAWSAzureGCP
M
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

From $92K/yr

Quick readStrong listing-quality and freshness signals

We are hiring a Senior Technical Product Marketing Manager to lead positioning and messaging and to grow adoption of MongoDB Search and Vector Search as foundational components of our platform – the retrieval layer powering the next generation of grounded AI applications and agents. This is a high-impact role for a marketer who thinks like a builder. As developers architect increasingly sophisticated systems – RAG pipelines, agentic workflows, multi-modal search experiences – retrieval has moved from an implementation detail to a core design decision. You’ll join a high-performing, globally distributed team and partner closely with Marketing, Builder Relations, Product Management, Engineering, Partners, and Sales to develop, measure, and achieve cross-functional goals. The role requires technical depth in information retrieval — lexical and vector search, hybrid approaches, embeddings, re-ranking, agentic retrieval loops, and the tradeoffs that matter in production systems — paired with the product marketing instincts to turn that depth into crisp, differentiated messaging for distinct user and buyer personas. Hands-on experience building or shipping AI-enabled products is a strong advantage. Individuals with prior experience in technical sales, developer relations, or technical marketing are encouraged to apply. This person is a voracious consumer of AI research and pays close attention to shifting patterns in application architectures and development, including agentic systems. This individual is confident in communicating with technical practitioners and non-technical decision makers in one-to-few and one-to-many engagements for internal and external audiences. We are looking to speak to candidates who are based in the US for our hybrid working model. What You’ll Do Drive Strategy & Execution: Act as a strategic partner for high-impact initiatives that align with MongoDB’s long-term business goals in collaboration with Marketing, Developer Relations, Product

MongoDBAWSAzureAI
M
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

From $114K/yr

Quick readStrong listing-quality and freshness signals

The Assurance, Risk and Compliance (ARC) Initiatives team at MongoDB owns the governance and delivery of key cross-functional security risk and compliance initiatives. The team designs and executes programs that support compliance audits, risk assessments, common control frameworks, operating cadences, and executive reporting that strengthen the organization’s assurance, risk management and compliance objectives. The policy and controls governance pillar is responsible for the structure, standards and operating mechanisms that keep MongoDB’s security policies, standards, procedures, and controls governance processes current, aligned, auditable and scalable across the organization. This includes ownership of the policy lifecycle, common controls framework governance, issue management, and the review cadences and cross-functional coordination needed to maintain strong governance maturity and audit readiness. This role sits under the Assurance, Risk and Compliance function within the Global Security Office and reports to the Director of ARC Initiatives. This role will be based remotely in the United States Responsibilities: Scope of Ownership Policy governance program ownership, including policy lifecycle management, documentation standards, review and approval cadences, change tracking, and exception governance Controls governance ownership, including common controls framework lifecycle management, control harmonization, framework mapping, and processes that support audit readiness and scalable control oversight Governance over supporting systems and workflows, including Jira, GRC tooling, documentation repositories, and reporting structures, that enable consistent execution and visibility Issue management and remediation governance, including intake, triage, tracking, and reporting for timely closure of findings Executive-ready reporting and metrics for policy health, controls maturity, policy exceptions and broader program effectiveness Program Leadership Own

MongoDBAWSAzureAI
M
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

From $127K/yr

Quick readStrong listing-quality and freshness signals

The Team Platform Engineering is the department within SRE that is responsible for a range of critical infrastructure and operational functions that support the broader engineering organization. Among these are our multi-cloud-provider Kubernetes infrastructure, deployment machinery, and observability and alerting systems. The Fabric team manages the infrastructure that enables secure communication between systems and from the public internet. Their responsibilities encompass network architecture, service mesh, and edge load balancing, ensuring customer data remains safe in transit. The team plays a crucial role in developing and maintaining the reliable and globally connected multi-cloud network that supports MongoDB products. This role can sit in our NYC HQ, our smaller Austin, Palo Alto, or San Francisco offices, or fully remote from anywhere in North America. When based in an office, we provide hybrid work accommodation. Role Overview We are seeking a talented Site Reliability Engineer (SRE) with a strong networking background to join the Fabric team. This role is pivotal in building and maintaining the robust infrastructure necessary for secure and efficient communication between our services. As an SRE on the Fabric team, you will leverage your expertise in networking, distributed systems, and automation to ensure our systems are resilient, scalable, and reliable. The ideal candidate should Have 10+ years of experience working on software and operating distributed systems, with deep expertise in networking fundamentals and a good understanding of how the internet works, e.g. TCP/IP (including IPv6), DNS, TLS/mTLS, BGP, tunnels, overlays, and SDN principles Possess a customer-focused mindset, driving improvements that benefit end-users Value efficiency in processes and operations, and display a strong preference for automation over manual processes (“allergic to ops work”) Be intimately familiar with modern cloud-based infrastructure and the network design prim

MongoDBAWSAzureGCP
M
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

From $126K/yr

Quick readStrong listing-quality and freshness signals

Our Database Experience (DBX) Team A great MongoDB experience starts with great tools. The Database Experience team builds the libraries and tools that developers use day-to-day working with MongoDB. Our mission is to increase developer adoption, satisfaction and retention by providing a reliable, enjoyable interface for developers and other end-users. Our senior engineers are typically specialists in a particular programming language, but are capable of contributing to projects in other languages as well. For this role, we're looking for someone who will enjoy designing, writing, and supporting open source libraries for the Python ecosystem developers that use MongoDB. This is an opportunity to make a major impact at MongoDB as Python is one of the most popular runtimes for MongoDB users, and our driver has over 3 million daily pypi downloads. You might be right for this role if you... Have substantial experience writing high-quality software in Python Have extensive knowledge in Python tools and frameworks, scientific python and web development frameworks Have practical experience with AI/ML frameworks and technologies in Python, including large language models and agentic tools are a plus Have an interest in learning and staying up-to-date with Python ecosystem trends and best practices and incorporating them into your work Can make pragmatic design decisions, balancing tradeoffs such as usability, maintainability and delivery time Want to, or already do, participate in open source software development and communities, both online via e.g. GitHub and optionally through conferences and speaking engagements Communicate well, internally and externally, both verbally and in writing Enjoy collaborating with teammates, and mentoring junior engineers and interns Are self-motivated, organized, and have strong time management skills You'll be on the team responsible for... Developing and supporting the MongoDB Python drivers and subsidiary libraries ( PyMongo , Django Mon

PythonMongoDBAWSAzure
M
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%
Quick readStrong listing-quality and freshness signals

The MongoDB Query Team is seeking a Senior Staff Product Manager to provide division-wide, product leadership for our fast, modular distributed query engine and flexible query system. As the most senior product management contributor, you will shape the multi-year strategy, product architecture, and market trajectory for the entire Query business unit. You will be the primary product authority on the most complex trade-offs, anticipating systemic risks and cutting through structural friction that blocks multiple teams and initiatives. This role requires collaboration with distinguished engineers to rigorously debate strategy and pressure-test assumptions and advise executive leadership on options that balance long-term monetization, strategy, and business outcomes. And, where relevant, owns the pricing and monetization strategy for the product line. We are looking to speak to candidates who are based in New York City for our hybrid working model. Responsibilities Product Vision and Roadmap: Spearhead strategic unity across multiple product areas over a multi-year horizon to drive a coherent product experience Business Leadership: Originate and de-risk the division’s most consequential strategic bets, owning rigorous business cases and advising leadership on multi-year economic outcomes Customer Advocacy: Engage with strategically significant customers at the senior level (e.g., advisory boards and executive briefings) to surface cross-portfolio opportunities and inform the roadmap PM Excellence: Elevate the global standard of product management by mentoring Staff and Senior PMs and pioneering new data-driven playbooks across the organization. Create frameworks and standards for customer and market research that others use for conducting high-quality customer and market research Cross-Functional Alignment and Execution: Partner with Directors and VPs to shape investment allocation and sequencing across the query, developer experiences, and core database p

SQLMongoDBAWSAzure
M
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

From $84K/yr

Quick readStrong listing-quality and freshness signals

A senior field and partner marketer who can translate Public Sector strategy into focused, measurable go-to-market execution across priority federal accounts, partner ecosystems, and high-impact market moments. We are looking to speak to candidates who are based in United States. About the Role MongoDB is seeking a Senior Marketing Manager, U.S. Public Sector to lead strategy and execution for key Public Sector marketing priorities, with a primary focus on federal growth motions. This role will translate business priorities into integrated marketing plans that strengthen account engagement, accelerate pipeline, deepen partner alignment, and build market momentum for MongoDB in highly regulated buying environments. This is a strategic, hands-on senior individual contributor role. The right candidate can independently lead complex, cross-functional programs; create clear operating rhythms; influence senior stakeholders across Sales, Partner, Product Marketing, Developer Relations, Customer Success, Communications, and Marketing leadership; and connect marketing activity to measurable business outcomes. The Senior Marketing Manager will play a central role in MongoDB’s Public Sector growth strategy by driving high-impact programs across priority agencies and partner-led routes to market. This includes helping activate major Public Sector growth moments, such as FedRAMP High-related go-to-market motions. This role reports to the Regional Marketing Lead and works closely with Public Sector Sales, Partner, and Marketing leadership. What You’ll Do Build and own the annual U.S. Public Sector marketing plan, aligning investments to business priorities, target segments, priority accounts, partner ecosystems, and pipeline goals Translate senior leadership direction into clear quarterly priorities, program plans, success metrics, and stakeholder operating rhythms across the Public Sector business Lead the strategy, planning, execution, and measurement of MongoDB’s flagship Publ

MongoDBAWSAzureAI
M
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

From $126K/yr

Quick readStrong listing-quality and freshness signals

Senior Forward Deployed Engineers (FDE) sit at the intersection of enterprise customer environments and a fast-moving internal product. They partner directly with customers to design, build, troubleshoot, and improve production solutions, and they are ultimately accountable for helping customers get to production. This role is best suited for engineers who want to own technical outcomes end to end: understanding what a customer is trying to build, shipping the integration, and feeding learnings back into the product roadmap. This role will be based remotely in the United States (East Coast). Responsibilities Customer success Serve as the primary technical owner for customer engagements from initial discovery through production rollout Understand each customer's architecture, constraints, and definition of success, and drive toward that outcome Manage expectations, communicate risks clearly, and help customers navigate technical decisions with confidence Technical integration Build the connectors, pipelines, and supporting tooling needed to make the platform work inside real enterprise environments Write production-quality code, troubleshoot issues, and implement fixes directly in active workstreams Work effectively within customer environments that have different stacks, infrastructure, and integration constraints Product feedback loop Capture product feedback with precision, including logs, reproduction steps, and a clear proposed path forward Use customer engagements to identify product gaps, surface recurring patterns, and help improve the product roadmap Document technical decisions and tradeoffs clearly so product and engineering teams can extend the work Workstream collaboration Partner closely with product and engineering teams to help turn field patterns into reusable product capabilities Contribute directly in focused workstreams by helping drive technical design, implementation, and delivery Make sound engine

MongoDBAWSAzureAI
M
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

From $151K/yr

Quick readStrong listing-quality and freshness signals

We’re looking for a Senior Engineering Manager who is ready to lead through ambiguity and improve how software gets built at MongoDB. This role leads teams focused on developer productivity, with an emphasis on measurable improvements to the software development lifecycle. This role can be based remotely in the United States. The Team The AXIS team (AI, X-functional tools, Insights, and Signals) sits within Developer Productivity and is responsible for overseeing the metrics and observability infrastructure of our expansive developer environment to help build a strong data-driven culture. You’ll also be a key partner in building the agentic ecosystem for AI-driven development across engineering. Candidate Profile We’re looking for an experienced leader with a passion for solving the big challenge of measuring developer productivity and providing the actionable signals that help teams improve their performance. They should be comfortable working collaboratively with other leaders and partners across our Engineering and Data teams in maximizing the use of data for insights and AI enablement. The right candidate for this role will have 4+ years of experience managing software engineers, including hiring, performance management, growth planning, and compensation; required for external candidates and preferred for internal candidates 8+ years of hands-on software engineering experience building and operating production systems; experience in developer tooling, platform engineering, observability, or data engineering is a strong plus Demonstrated the ability to lead through ambiguity, work across team boundaries, and deliver outcomes without close supervision Strong customer orientation and sound judgment in finding practical, high-leverage solutions Experience working with systems involving analytics, data pipelines, and metrics platforms Experience with AI tools development and enablement efforts Strong technical judgment, including the ability to evaluate t

MongoDBAWSAzureAI
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