Ai Senior Systems Engineer in New York

Who We Are Notion is the collaborative AI workspace where teams and agents think together . We're building one place where your knowledge, projects, meetings, and AI tools live side by side, so work is faster, clearer, and less fragmented. Millions of individuals, small teams, and large companies run their work on Notion. Notinos (our employees) are customer zero in bringing this future of work to life. We care about craft, building things that last, and the belief that great work is still fundamentally human. Our goal isn’t to ship the next feature. Each and every team of Notinos is working to set the standard for how humans work together in the AI era. From building a business’s system of record to making and managing AI agents to automating away the busy work, we care deeply about giving our customers more time for their life’s work. About the Role You’ll lead the Mobile AI engineering team, responsible for making Notion AI genuinely useful on phones and tablets. Mobile is where AI needs to work in the moment: when users are capturing ideas, catching up between meetings, asking questions, or trying to move work forward away from their desk. This role can be based in either San Francisco or New York City. We work from our offices on Mondays, Tuesdays and Thursdays (our Anchor Days) because we do our best thinking and building together in person. We’re looking for someone who’s excited to work alongside the team during those days. What You'll Achieve Define and evolve the roadmap for Notion’s core mobile AI surfaces, including chat, capture, agent workflows, workspace Q&A, and lightweight creation flows. Take new mobile AI ideas from exploration to shipped product, using prototypes, user feedback, and product data to decide what to build next. Improve the production quality of mobile AI by identifying instrumentation gaps, reliability risks, and performance bottlenecks before they become user problems. Help the team build the right technical foundations for fas

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Product at Brex The Product team is at the forefront of Brex's mission to empower employees anywhere to make better financial decisions. With a deep understanding of the business, we identify and scope out the most impactful opportunities for Brex to tackle. We are responsible for aligning cross-functional teams — such as Engineering, Legal, Compliance, and Design — on key decisions. We set strategy and drive products from inception to launch, enabling Brex to grow rapidly and help our customers reach their full potential. Unlocking AI Agents for the Finance Admin Companies buy Brex to run their spend, and the person on the hook for that is the finance admin — a controller, an accounting manager, a finance ops lead. Their job comes down to two things they can never quite get ahead of: making sure money is being spent compliantly and documented in time to close the books, and knowing where the company's money is actually going. Today t

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Product at Brex The Product team is at the forefront of Brex's mission to empower employees anywhere to make better financial decisions. With a deep understanding of the business, we identify and scope out the most impactful opportunities for Brex to tackle. We are responsible for aligning cross-functional teams — such as Engineering, Legal, Compliance, and Design — on key decisions. We set strategy and drive products from inception to launch, enabling Brex to grow rapidly and help our customers reach their full potential. What you’ll do As a Product Leader at Brex, you will be the driving force behind our Growth Product team — overseeing the thoughtful strategy and execution of team and technical systems to drive customer acquisition and onboarding. You will also collaborate closely with our Go-to-Market (GTM) teams to ensure seamless acquisition and onboarding for customers, particularly those with significant and complex spending n

About the Team The Technical Success team helps OpenAI’s customers realize meaningful and sustained value from our technology. We partner with customers throughout their journey—from initial exploration and solution design to production implementation and organization-wide adoption. Applied AI Engineers serve as trusted technical partners to customer executives, engineering teams, product leaders, security organizations, and transformation teams. They combine deep technical judgment with strong customer instincts, translating frontier AI capabilities into secure, reliable systems and durable business outcomes. About the Role We are seeking a Manager to build, lead, and develop a high-performing team of Applied AI Engineers supporting our enterprise customers. You will be accountable for the technical success of a broad and strategically important customer portfolio. You will help your team identify high-value opportunities, design and deploy production-grade AI systems, navigate complex technical and organizational constraints, and expand successful implementations across workflows, teams, and business units. This role requires technical depth, people leadership, customer judgment, and operational rigor. You should be comfortable coaching engineers through architecture and evaluation decisions, engaging directly in high-stakes customer situations, and collaborating with Sales, Solutions Engineering, Product, Research, Engineering, Security, and Legal. You will also help define how we serve enterprise customers at scale by developing effective coverage models, reusable implementation patterns, technical enablement, escalation mechanisms, and systems for turning field insights into high-quality product feedback. In This Role, You Will Build, manage, and develop a high-performing team of Applied AI Engineers supporting large and complex enterprise customers. Own the quality and impact of the team’s work across solution design, implementation, production readiness, adop

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. LEAD. STRATEGIZE. TRANSFORM. We are seeking an advanced professional handling complex enterprise AI/ML deployments, deconstructing system dependencies, and ensuring production robustness. WHY THIS ROLE? This role marks a shift from managing tactical tasks to managing strategic outcomes. You are a seasoned professional with a full understanding of your specialization, resolving a wide range of issues in creative ways. WHAT YOU'LL DO: Design robust, scalable AI/ML solutions utilizing the full Snowflake native stack and partner ecosystem. Perform deep-dive Root Cause Analysis (RCA) for complex system dependencies in AI/ML solutions. Collaborate cross-functionally with Sales and Product teams to align technical roadmaps with customer ROI. Mentor Level 3 architects on best practices for MLOps and architectural design. TECHNICAL DEPTH & RISK MANAGEMENT: Distributed Systems: Deconstruct failures in complex pipelines involving external cloud services (AWS/Azure/GCP). Predictive Failure Analysis: Critically think about potential failure modes like model drift and data skew early in the lifecycle. Governance: Architect data security and access controls specifically for sensitive AI/ML training data. SNOWFLAKE-NATIVE TECH STACK: Snowflake Model Registry, Cortex Functions, Python,

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. At Snowflake, we empower both enterprises and individuals to reach their full potential. Our culture prioritizes impact, innovation, and collaboration, making Snowflake the ideal place to build ambitious projects, execute quickly, and advance technology — and your career — to the next level. The Role We are seeking a Manager, Applied Field Engineering - AI/ML Product Specialists to lead a high-performing team of Applied Field Engineers within the Applied Field Engineering organization. In this hands-on leadership role, you will manage a team of Applied Field Engineers who specialize in Generative AI, Machine Learning, and Advanced Analytics. You will be responsible for coaching your team through technical sales engagements, driving execution excellence, and ensuring customers successfully activate and consume Snowflake's AI/ML capabilities. You will translate team-level insights into feedback that shapes broader strategy, working closely with your manager and cross-functional partners to align execution with organizational priorities. Responsibilities & Focus Areas: Technical Execution & Consumption Activation: Drive team performance toward Consumption Activation — ensuring customers successfully move workloads into production and realize contracted credit value Coa

Datadog is seeking a Director of Product Management to lead our AI Observability portfolio and shape how organizations build, monitor, and scale AI systems in production. This role leads LLM Observability and helps define the next wave of innovation across GPU Monitoring, Distributed AI Monitoring, and emerging research-oriented tooling such as Model Lab. You will set the vision and strategy for this rapidly growing area, expanding established products while incubating new capabilities that deliver deep visibility into AI infrastructure, model performance, and distributed AI environments. As AI becomes core to modern applications, this team plays a critical role in ensuring customers can deploy and scale AI with confidence. We’re looking for a builder-minded product leader with strong technical depth and hands-on curiosity - someone who has built or worked closely with AI-powered products and understands the realities of production AI. You will lead a team of product managers and partner closely with engineering and design to advance Datadog’s leadership in AI observability. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Own the vision and strategy for AI-driven products, ensuring alignment with overall company goals and customer needs. This will include managing our embed program to enhance the capabilities of existing products as well as developing dedicated and independent AI products. Lead and mentor a team of product managers, helping them grow and advance their careers while ensuring the delivery of high-quality, AI-powered features. Collaborate with cross-functional teams including engineering, data science, marketing, and sales to deliver AI product solutions that meet customer needs and business objectives. Identify new opportunities for

About the Team The Astral team builds high-performance developer tools to power the future of programming, at OpenAI and beyond, including Ruff, uv, and ty. The Astral toolchain sees hundreds of millions of installs per month and powers hundreds of millions of package downloads per day for the Python ecosystem. As a team, we are building on those foundations to continue solving impactful tooling problems as programming evolves. About the Role We are looking for an experienced software engineer to build next-generation programming language tooling. If you like writing high-performance Rust, it could be a good fit; if you like thinking about the future of programming, it could also be a good fit. Strong candidates tend to have deep experience with Rust, Python, open source, compilers, or developer tools — but few candidates are deep in all of these areas, and we've hired candidates without prior Rust or Python experience. In this role, you will: Design and implement features in Astral’s existing open source projects (Ruff, uv, ty, and python-build-standalone, and more). Support Astral’s open source projects as a maintainer, triaging user issues, reviewing pull requests, and participating in community discussions. Evolve the Astral toolchain to accelerate development velocity at OpenAI. Build entirely new tools, in entirely different programming ecosystems, to power the future of agentic software development. Your background might look something like: 5+ years of professional engineering experience, excluding internships, in relevant engineering roles. High agency and comfort operating in a fast-moving environment, with strong ownership of security, reliability, and operational excellence. Strong developer empathy and communication skills, including experience maintaining open source projects. Exceptional systems engineering fundamentals and a track record of leading complex projects from ambiguous problem statements through to user impact. Proficiency in one or more s

ROLE SUMMARY The primary purpose of this job role is to function as a member of the Sample Logistics (SL) operations within Pfizer Vaccine Research and Development (VRD). The incumbent will be responsible for receiving samples from global clinical/study trials according to approved protocols and processes. The individual will participate in all aspects of tracking and documenting the chain of custody of samples. The incumbent’s role will include sample receipt, documentation, storage, tracking, aliquoting, distribution to the testing labs, and sample disposal. The colleague will work in a team setting and will share roles and responsibilities as assigned by the team leader/manager. ROLE RESPONSIBILITIES The incumbent will be required to complete all processes as detailed in Sample Management’s Standard Operating Procedures. The colleague will perform job responsibilities in compliance with GXP and all other regulatory agency requirements. The candidate will receive samples from clinical trial sites and enter samples into an electronic database management system. Performs sample storage and retrieval using manual freezers and BiOS (automated freezer storage system). Performs manual sample aliquoting and aliquoting using the Hamilton robotic instrument. <span style="color:#

ROLE SUMMARY This is a laboratory-based position within the Vaccine Research and Development, EBPD – Analytical GLP laboratory group. The individual will perform routine sample testing, assay verification and qualification studies in support of material characterization for vaccine GLP toxicology studies. Assays include but are not limited to enzyme-linked immunosorbent assays (ELISAs) and other plate-based testing, Antigenicity by MSD and Hamilton, HPLC, spectroscopic techniques (UV-Vis), Endotoxin, Bioburden, pH and Appearance. This position will require work on fast-moving high-visibility projects within regulated GLP laboratory environment. ROLE RESPONSIBILITIES Under direct supervision, perform sample testing in support of toxicology studies, including release, stability, and assay qualification. Ability to perform necessary calculations independently and discuss conclusions with their manager. Document experiments and analyze data from sample testing and method qualification experiments using an electronic laboratory notebook and LIMS with guidance. Contribute to the authoring of technical documents including assay qualification reports, analytical test methods, stability protocols/reports. Assure safety and compliance. Provide daily laboratory operations support. QUALIFICATIONS Basic Qualifications: BS or BA degree in biology or related discipline with 0- 2 years relevant experience. · Basic knowledge of bioassay analytical techniques. Strong verbal and written communication skills. Proficiency with personal computers including word processing, spreadsheets, PowerPoint and relevant scientific software is required. Preferred Qualifications: Prior experience work

ROLE SUMMARY The Clinician Medical Monitor is accountable for providing medical and scientific expertise and oversight for Clinical Trials and serves as a single point of accountability for design, execution, monitoring, delivery and reporting of one or more clinical studies and to ensure patient safety. The clinician medical monitor may be required to design a development strategy for multiple protocols designed to obtain worldwide approval for a compound or group of compounds. In addition to study level activities, the clinician medical monitor may participate in standing committees, review compounds for potential in-licensing, including performance of due diligence reviews, and aid new business development on market opportunities and the target product profile. ROLE RESPONSIBILITIES Accountable for safety across the study Provide study team with medical advice for all medical issues during risk assessment and mitigation planning to enable quality, compliance and patient safety at the trial, site and patient level. Ensures development of and adherence to the Safety Surveillance Review Plan (SSRP). Consistent with the SSRP, performs and documents regular review of individual subject safety data, and performs review of cumulative safety data with the safety risk lead. As appropriate, the clinician medical monitor may delegate these responsibilities to the study clinician scientist identified in the SSRP. The specific components of safety data review are detailed in the appropriate SOPs and the “Safety Data Review Guide – for Clinicians.” Monitor study safety issues and provide input to serious adverse events (SAEs) reports. Provides appropriate medical context in terms of risk factors, medical history and other important medical factors required to put the SAE or AE into appropriate medical context required for benefit-risk assessm

ROLE SUMMARY The primary purpose of this job role is to function as a member of the Sample Logistics (SL) operations within Pfizer Vaccine Research and Development (VRD). The incumbent will be responsible for receiving samples from global clinical/study trials according to approved protocols and processes. The individual will participate in all aspects of tracking and documenting the chain of custody of samples. The incumbent’s role will include sample receipt, documentation, storage, tracking, aliquoting, distribution to the testing labs, and sample disposal. The colleague will work in a team setting and will share roles and responsibilities as assigned by the team leader/manager. ROLE RESPONSIBILITIES The incumbent will be required to complete all processes as detailed in Sample Management’s Standard Operating Procedures. The colleague will perform job responsibilities in compliance with GXP and all other regulatory agency requirements. The candidate will receive samples from clinical trial sites and enter samples into an electronic database management system. Performs sample storage and retrieval using manual freezers and BiOS (automated freezer storage system). Performs manual sample aliquoting and aliquoting using the Hamilton robotic instrument. Ship samples and lab supplies to external and internal testing labs. Assists in the general maintenance of the Hamilton robotic instruments. Participates in the shipment discrepancy resolution process. Completes documentation according to cGMP/GLP and all other regulatory agency requirements and archives documents as per applicable policies. Carries out sample disposal/sample destruction according to regulated policies and procedures Performs other duties as assigned. QUALIFICATIONS Must Have Bachelor of Science Degree or Bachel

Why Patients Need You Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world. What You Will Achieve As an Associate Scientist, you will be at the center of our operations and you’ll find that everything we do, every day, is in line with an unwavering commitment to quality. In this role, you will join a team of scientists focused on optimizing biologics reagents for vaccine programs. Your primary role is to support, assist and deliver reagents for nonclinical and clinical targets within Vaccines. Likewise, you’re expected to have a strong foundation in general scientific practice and the principles and concepts that will support meeting critical deadlines. You will be performing aseptic serological processing, preparation of buffers, and growing bacterial cultures, as necessary. All work is to be done in a compliant manner according to relevant SOP guidelines and GLP and/or GMP guidelines, as required. How You Will Achieve It Perform aseptic serological processing, reagent preparation, and bacterial culture growth to support high throughput clinical and nonclinical testing in Vaccines. Complete all work in compliance with SOPs, safety guidelines, and Good Laboratory Practice (GLP) requirements. Utilize time management, organization, detail orientation, and strong interpersonal skills to effectively perform tasks to support clinical immunology and diagnostics. Complete ad h

#Team Nextdoor Nextdoor (NYSE: KIND) is the essential neighborhood network. Neighbors, public agencies, and businesses use Nextdoor to connect around local information that matters in more than 350,000 neighborhoods across 11 countries. Nextdoor builds innovative technology to foster local community, share important news, and create neighborhood connections at scale. Download the app and join the neighborhood at nextdoor.com . Meet your Future Neighbors Nextdoor Account Managers are a diverse, driven, and strategic group of client services and salespeople focused on connecting brands with our community of neighbors through our growing portfolio of advertising products. The team culture mirrors the larger business focus, relying on building trusted relationships both internally as well as with our partners. The team drives results for our brand partners while creating neighbor value. We're a purpose-driven company and we're recruiting like-minded client services professionals who are as passionate about customer value as they are professional growth, and building a culture of belonging. At Nextdoor, we operate in an AI-first environment and expect every team member to actively use AI tools as part of their workflow. We aren't looking for prompt engineers; we’re looking for people who use tools like Claude, Gemini, ChatGPT, and Glean to challenge their own thinking and take full ownership of AI-assisted outputs. We also offer a warm and inclusive work environment that embraces a hybrid employment model, blending an in office presence and work from home experience for our valued employees. The hiring team will go over these expectations with you if you are being considered for a role near one of our offices in San Francisco, Los Angeles, Chicago, Dallas, New York, and London. The Impact You’ll Make Nextdoor’s Account Management team helps advertisers by connecting them with our hyper-local community of neighbors across the United States through our native a

About Glean: Glean is the Work AI platform that helps everyone work smarter with AI. What began as the industry’s most advanced enterprise search has evolved into a full-scale Work AI ecosystem, powering intelligent Search, an AI Assistant, and scalable AI agents on one secure, open platform. With over 100 enterprise SaaS connectors, flexible LLM choice, and robust APIs, Glean gives organizations the infrastructure to govern, scale, and customize AI across their entire business - without vendor lock-in or costly implementation cycles. At its core, Glean is redefining how enterprises find, use, and act on knowledge. Its Enterprise Graph and Personal Knowledge Graph map the relationships between people, content, and activity, delivering deeply personalized, context-aware responses for every employee. This foundation powers Glean’s agentic capabilities - AI agents that automate real work across teams by accessing the industry’s broadest range of data: enterprise and world, structured and unstructured, historical and real-time. The result: measurable business impact through faster onboarding, hours of productivity gained each week, and smarter, safer decisions at every level. Recognized by Fast Company as one of the World’s Most Innovative Companies (Top 10, 2025), by CNBC’s Disruptor 50, Bloomberg’s AI Startups to Watch (2026), Forbes AI 50, and Gartner’s Tech Innovators in Agentic AI, Glean continues to accelerate its global impact. With customers across 50+ industries and 1,000+ employees in more than 25 countries, we’re helping the world’s largest organizations make every employee AI-fluent, and turning the superintelligent enterprise from concept into reality. If you’re excited to shape how the world works, you’ll help build systems used daily across Microsoft Teams, Zoom, ServiceNow, Zendesk, GitHub, and many more - deeply embedded where people get things done. You’ll ship agentic capabilities on an open, extensible stack, with the craf