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Ai Systems Engineer in San Francisco

1,456 active opportunities · Updated October 2026

Explore current ai systems engineer jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team Our Cyber team builds AI systems and products that help trusted defenders understand and respond to cyber threats while improving the safety and reliability of frontier models in security-sensitive settings. The team works across product engineering, model training, evaluations, safeguards, and deployment to make advanced cyber capabilities useful to defenders and responsibly managed. We collaborate closely with Safety/Preparedness, Research, Security, Legal, Communications, GTM, and external partners across OpenAI’s broader cyber work. About the Role We’re looking for research and software engineers to join Codex Cyber. You’ll help define and ship security products, work with trusted defenders and customers, shape model training and access patterns, and build research and evaluation systems for assessing cyber capabilities, validating safeguards, and improving training data. This role is hands-on and cross-functional, connecting product launches, model development, safety work, and real-world security use cases. In this role, you will: Help define and execute the technical roadmap for Codex Cyber’s security products, including evaluations, safeguards, trusted-defender workflows, and deployment decisions. Work with trusted defenders, customers, and partner teams to understand cyber use cases, evaluate risk, and turn feedback into product and research priorities. Shape cyber-specific model training and access patterns, including data, evaluations, validation, and deployment criteria. Build and validate systems for measuring cyber capabilities, monitoring misuse risk, and proving safeguards work in practice. Collaborate with Safety/Preparedness, Research, Security, Legal, Communications, Go-to-Market, and external partners on company-wide cyber priorities. Translate frontier cyber research into launch-ready tools, operational playbooks, and durable infrastructure for Codex and security products. You might thrive in this role if you: Enjoy 0 -> 1 envi

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team GTM Growth Engineering builds AI-native products and systems that help OpenAI's go-to-market and B2B marketing organizations operate with greater speed, focus, and leverage. Our mandate is revenue leverage: products tied directly to pipeline quality, customer engagement, seller and marketer productivity, and the speed at which OpenAI can bring its technology to customers. We build the infrastructure and user experiences behind high-impact GTM workflows, including customer context, prioritization, routing, campaign execution, review surfaces, feedback loops, and measurement. Our work combines product craft, applied AI, reliable systems, and thoughtful operational design. About the Role We’re looking for a product-minded Software Engineer to build AI-powered products and full-stack experiences for GTM Growth Engineering. You will own meaningful product slices end to end, from user experience and frontend implementation to backend APIs, integrations, data models, instrumentation, and launch readiness. This is a role for engineers who want to build products that do real work in production. You will partner with Product, Design, Data Science, Sales, B2B Marketing, and operations teams to understand high-value workflows and ship systems that improve customer engagement, pipeline, conversion, and team productivity. The role is ideal for a strong product engineer who can move between product craft, systems engineering, applied AI, and measurable business outcomes. You should be excited to build from ambiguous problem statements, ship quickly, and improve products based on real user feedback. What You'll Do Build AI-powered products and workflows that help sales and B2B marketing teams identify opportunities, coordinate work, and engage customers more effectively. Own full-stack product experiences from prototype through launch, instrumentation, iteration, and production hardening. Design intuitive user journeys that combine polished interfaces, reliable servi

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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the Team OpenAI’s Healthcare team is working to ensure that advances in AI meaningfully improve health for everyone. We build AI systems that support patients, clinicians, and healthcare organizations while setting a high standard for deploying AI responsibly in a high-stakes domain. On the Healthcare team, we are building products and infrastructure that bring OpenAI’s capabilities into healthcare organizations and clinical workflows. We serve health care systems, insurance companies, and the broad range of healthcare IT companies. Our products include connecting ChatGPT with healthcare data and systems and building reliable enterprise experiences that can operate within complex security, privacy, compliance, and interoperability requirements. We work closely with product, research, design, security, privacy, GTM, and our healthcare customers to turn powerful AI capabilities into dependable products that clinicians and healthcare organizations use in their everyday work. About the Role We are looking for backend and full-stack software engineers to build the systems behind OpenAI’s healthcare products. You will work across backend services, APIs, data systems, integrations, and product surfaces to connect AI with healthcare workflows and enterprise data. You’ll tackle the technical challenges involved in making these systems secure, reliable, observable, and scalable enough for real-world healthcare environments. This is a product-engineering role for someone who can move between customer problems and complex system architecture, and who is comfortable owning ambiguous problems end-to-end. In this role, you will: Design and build backend and full-stack systems powering OpenAI’s healthcare products. Build services, APIs, and data pipelines that connect OpenAI products with healthcare systems and enterprise data. Develop integrations with electronic health records and other healthcare data sources. Design systems that meet demanding requirements around privacy,

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

Join the engineering teams that bring OpenAI’s ideas safely to the world! The Applied Engineering team works across research, engineering, product, and design to bring OpenAI’s technology to consumers and businesses. We seek to learn from deployment and distribute the benefits of AI, while ensuring that this powerful tool is used responsibly and safely. Safety is more important to us than unfettered growth. About the Role As OpenAI continues to grow, we are looking for experienced, problem-solving engineers to ensure our systems scale. Our success depends on our ability to quickly iterate on products while also ensuring that they are performant and reliable. You will work in a deeply iterative, collaborative, fast-paced environment to bring our technology to millions of users around the world, and ensure it’s delivered with safety and reliability in mind. Successful candidates will play a crucial role in ensuring the reliability, scalability, and performance of our systems as we continue to expand. As a reliability expert, you will be at the forefront of maintaining and enhancing the stability, scalability, and performance of our rapidly evolving infrastructure. You will work closely with cross-functional teams, including software engineers, product managers, and data scientists, to build and maintain resilient systems that can handle our growing user base and workload. In this role, you will: Design and implement solutions to ensure the scalability of our infrastructure to meet rapidly increasing demands. Build and maintain the load, chaos and synthetic-testing software leveraged by development teams to make the systems they design and operate more reliable. Build and maintain automation tools to streamline repetitive tasks and improve system reliability. Build and maintain the platform for CPU, storage, GPU, and network lifecycle management to drive efficiency, accountability and dynamic optimization of our resources. Implement fault-tolerant and resilient design

AWSKubernetesRestMicroservices
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s Applications Engineering organization builds and operates the products (such as ChatGPT & Codex) that bring our cutting-edge research to millions of users and developers worldwide. The Applied Foundations team owns the core product and platform layers that make those experiences possible — from identity & access, to safety to payments & commerce across all of our apps. Our teams span product engineering, infrastructure, and safety, working together to deliver technology that is reliable, secure, and trusted at global scale. About the Role We’re hiring Backend Software Engineers to design and implement safe services and infrastructure that power our core products. What You’ll Do Architect, build, and improve scalable backend systems and APIs. Drive performance, reliability, and safety across distributed services. Implement data storage, retrieval, compute, and integration solutions. Participate in long-term architectural planning and technical design reviews. Collaborate with cross-functional teams to design solutions that protect against and mitigate adversarial attacks without compromising user experience. You Might Thrive Here If You: Have strong experience with distributed systems, APIs, and backend languages (e.g., Go, Python, Rust, C++). Have experience setting up and maintaining production backend services and data pipelines. Have a humble attitude, an eagerness to help your colleagues, and a desire to do whatever it takes to make the team succeed. Enjoy building resilient services that handle large scale and complexity. Are self-directed and enjoy figuring out the best way to solve a particular problem Own problems end-to-end, and are willing to pick up whatever knowledge you're missing to get the job done. About OpenAI OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We push the boundaries of the capabilities of AI systems and seek

PythonAWSRestAI
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s API Multicloud team is responsible for extending OpenAI’s API platform into strategic cloud environments, starting with AWS . The team’s mission is to distribute OpenAI’s API broadly and safely by enabling key API technologies in AWS-native environments, in close partnership with Amazon and internal teams across Codex, Research, Safety Systems, and Applied. The team is focused on bringing core developer and enterprise capabilities into cloud-native environments, including AWS-hosted Codex, model customization / post-training as a service, and new stateful runtime environments for agentic workloads. This work sits at the intersection of production ML systems, developer platforms, model behavior, and large-scale infrastructure. About the Role We’re hiring Machine Learning Engineers to build and improve the AI systems that help strategic partners adapt OpenAI models to important use cases in cloud-native environments. This role spans post-training workflows, evaluation, data pipelines, model behavior, and API/infrastructure integration. You’ll work at the boundary between partner needs and core ML systems: helping teams understand what is and isn’t working, diagnosing issues in training and evaluation workflows, and turning those learnings into improvements to the underlying platform. You should enjoy working with external technical partners, extracting the real goal from messy requests, and pushing back or reframing when the requested experiment is not the highest-leverage path. You’ll collaborate closely with Research, Applied, Safety Systems, infrastructure teams, and external technical partners to solve ambiguous model-performance problems. When you succeed, strategic partners and internal teams will be able to improve model behavior with confidence, driving measurable product improvements while the systems behind that work become more reliable, scalable, and effective over time. In this role, you will Partner with strategic customers and in

PythonAWSKubernetesRest
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Legal team is building the next generation of AI-powered products and experiences for the legal industry. We are exploring how advanced AI systems can transform legal workflows, improve access to information, and enable legal professionals and organizations to work more effectively. As a founding member of the Legal engineering team, you will help define the technical foundation for this new product area from the earliest stages. You’ll operate at the intersection of AI, product, and real-world legal workflows—identifying opportunities, building prototypes, and turning emerging ideas into scalable products that can create meaningful impact. We operate with a startup-like mindset inside OpenAI: small teams, rapid iteration cycles, and a willingness to explore bold ideas, learn quickly, and adapt based on user feedback. Our goal is to build products that meaningfully improve how legal professionals work while leveraging OpenAI’s cutting-edge models and infrastructure. About the Role As a Founding Full-Stack Software Engineer on the Legal team, you will help imagine, build, and scale new AI-powered products for the legal industry. You’ll work across the stack to design intuitive user experiences, build robust backend systems, and create the foundations for products used by legal professionals and organizations around the world. You’ll have significant ownership from the earliest stages—working closely with product, design, research, and go-to-market partners to understand customer needs, shape product direction, and deliver high-impact solutions. This includes rapidly prototyping new concepts, building production-quality applications on top of OpenAI’s platforms, and developing new technical approaches when existing systems are not sufficient. We’re looking for engineers who thrive in ambiguity, have strong product instincts, and enjoy building from 0→1. You should be comfortable moving quickly, making thoughtful technical decisions, and taking owner

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team With Codex we’re building an AI software engineer. One that you can pair with, delegate to, or even ask to take on future tasks proactively. Our team is a fast-moving group within OpenAI, bringing together research, engineering, design, and product. We iteratively build the Codex agent harness and product to get the most out of the model, and we iteratively train the model to be great at complex software engineering tasks. The Codex team is responsible for building state-of-the-art AI systems that can write code, reason about software, and act as intelligent agents for developers and non-developers alike. We operate across research, engineering, product, and infrastructure; owning the full lifecycle of experimentation, deployment, and iteration on novel coding capabilities. Codex Enterprise builds the ecosystem, governance, and enterprise capabilities that help Codex spread across developers, teams, and organizations worldwide. The User Activation team owns the product experiences that help developers discover Codex, understand its capabilities, connect it to their workflows, and turn initial usage into sustained adoption across teams. About the Role As Codex adoption grows, our challenge is no longer just building powerful AI capabilities. It is helping developers and teams quickly understand how Codex fits into their work, connect it to the tools and codebases they already use, and unlock workflows that make Codex feel like a true teammate. This role will help build the full-stack product surfaces that drive activation and adoption across Codex Enterprise. You will work across onboarding, workspace setup, integrations, discovery, collaboration, usage insights, and ecosystem capabilities that help Codex spread naturally through organizations. You will partner closely with product, design, research, infrastructure, GTM, and customers to identify where users get stuck, where teams fail to adopt Codex, and what product experiences can turn curiosity int

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The ChatGPT organization at OpenAI supports our mission by bringing advanced AI capabilities to hundreds of millions of users worldwide. The Image Generation team is responsible for one of the fastest-growing experiences in ChatGPT, enabling users to create, edit, and transform images through natural language. Recent breakthroughs in multimodal AI have dramatically improved image quality, instruction following, editing precision, consistency, and text rendering. We're building the systems and experiences that turn these research advances into products used daily by creators, professionals, businesses, and consumers around the world. Our team sits at the intersection of research, product, design, and infrastructure. We work closely with model researchers, mobile engineers, frontend engineers, and platform teams to build intuitive experiences and scalable systems that power image generation at global scale. Whether users are creating marketing assets, visualizing ideas, editing photos, designing products, or simply exploring their creativity, our goal is to make visual creation feel as natural as having a conversation. About the Role We are looking for an experienced Full Stack Engineer to join the Image Generation team and help shape the future of AI-powered visual creation. In this role, you'll own features end-to-end across both frontend and backend systems, building the experiences that enable users to generate, edit, organize, and interact with images inside ChatGPT. You'll work across the entire stack—from highly interactive user interfaces and real-time workflows to backend services, APIs, orchestration systems, and data infrastructure. This role is ideal for engineers who enjoy moving fluidly between product development and systems engineering, collaborating closely with design, product, and research teams to rapidly bring new AI capabilities to users. You'll help define entirely new interaction paradigms as multimodal AI continues to evolve. In

TypeScriptReactAWSRest
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s Applications Engineering organization builds and operates the products (such as ChatGPT & Codex) that bring our cutting-edge research to millions of users and developers worldwide. The Applied Foundations team owns the core product and platform layers that make those experiences possible — from identity & access, to safety to payments & commerce across all of our apps. Our teams span product engineering, infrastructure, and safety, working together to deliver technology that is reliable, secure, and trusted at global scale. About the Role We’re hiring Full-Stack Software Engineers to design and implement safe services, systems and infrastructure that power our core products. In this role, you will: Architect, build, and improve frontend and backend systems. Work across the full stack to build products and systems from initial exploration through launch readiness. Participate in long-term architectural planning and technical design reviews. Collaborate with cross-functional teams to design solutions that protect against and mitigate adversarial attacks without compromising user experience. You might thrive in this role if you: Have built and shipped full-stack apps or systems end-to-end — in fast-moving, startup-like environments. Have a humble attitude, an eagerness to help your colleagues, and a desire to do whatever it takes to make the team succeed. Enjoy building resilient products and services that handle large scale and complexity. Are self-directed and enjoy figuring out the best way to solve a particular problem Own problems end-to-end, and are willing to pick up whatever knowledge you're missing to get the job done. About OpenAI OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We push the boundaries of the capabilities of AI systems and seek to safely deploy them to the world through our products. AI is an extremely powerful tool t

AWSRestAIRust
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team With Codex we’re building an AI software engineer. One that you can pair with, delegate to, or even ask to take on future tasks proactively. Our team is a fast-moving group within OpenAI, bringing together research, engineering, design, and product. We iteratively build the Codex agent harness and product to get the most out of the model, and we iteratively train the model to be great at complex software engineering tasks. The Codex team is responsible for building state-of-the-art AI systems that can write code, reason about software, and act as intelligent agents for developers and non-developers alike. We operate across research, engineering, product, and infrastructure; owning the full lifecycle of experimentation, deployment, and iteration on novel coding capabilities. Codex Enterprise builds the ecosystem, governance, and enterprise capabilities that help Codex spread across developers, teams, and organizations worldwide. The Enterprise Controls team owns the systems that allow companies to safely deploy Codex across their organization while protecting their most sensitive code, data, and internal knowledge. About the Role As Codex adoption grows inside large organizations, customers are increasingly trusting Codex with their most valuable assets: proprietary codebases, internal documentation, customer data, and sensitive workflows. This role will help build the enterprise control plane that makes Codex secure, governable, and trustworthy at scale. You will design and operate backend systems that give enterprise administrators visibility and control over how Codex is used across their organization. You will work across identity, access, encryption, policy enforcement, auditability, and admin controls. This may include systems that let customers manage encryption keys, control which Codex capabilities are enabled, enforce organizational policies, and understand how data flows through Codex. This role owns systems end-to-end: from architecture and

PythonJavaAWSRest
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Applied Engineering team works across research, engineering, product, and design to bring OpenAI’s technology to consumers and businesses. You’ll join the team responsible for running the core infrastructure that supports products like ChatGPT and the API. The systems we support include our kubernetes clusters, infrastructure deployment, our networking stack, cloud abstractions, and more. We seek to learn from deployment and distribute the benefits of AI, while ensuring that this powerful tool is used responsibly and safely. Safety is more important to us than unfettered growth. About the Role The cloud infrastructure team builds and maintains infrastructure abstractions allowing OpenAI to ship products quickly and scalably. This role is based in San Francisco, CA. In this role, you will: Design and build the development and production platforms that power our products, enabling reliability and security at scale Ensure our infrastructure can scale to the next order of magnitude Help create a diverse, equitable, and inclusive culture that makes all feel welcome while enabling radical candor and the challenging of group think Like all other teams, we are responsible for the reliability of the systems we build. This includes an on-call rotation to respond to critical incidents as needed. You might thrive in this role if you: Have 5+ years building core infrastructure Have experience operating orchestration systems such as Kubernetes at scale Have experience building abstractions over cloud platforms Take pride in building and operating scalable, reliable, secure systems Are comfortable with ambiguity and rapid change This role is exclusively based in our San Francisco HQ. We offer relocation assistance to new employees. About OpenAI OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We push the boundaries of the capabilities of AI systems and seek to safely depl

AWSKubernetesRestAI
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team With Codex we’re building an AI software engineer. One that you can pair with, delegate to, or even ask to take on future tasks proactively. Our team is a fast-moving group within OpenAI, bringing together research, engineering, design, and product. We iteratively build the Codex agent harness and product to get the most out of the model, and we iteratively train the model to be great at complex software engineering tasks. The Codex team is responsible for building state-of-the-art AI systems that can write code, reason about software, and act as intelligent agents for developers and non-developers alike. We operate across research, engineering, product, and infrastructure; owning the full lifecycle of experimentation, deployment, and iteration on novel coding capabilities. Codex Enterprise builds the ecosystem building blocks, discovery surfaces, and enterprise capabilities that help Codex spread across developers, teams, and organizations worldwide. It is a cross-cutting team that works across the stack to build both delightful product experiences and fundamental platform capabilities. Its customers range from individual developers and small teams to large enterprises, and our mission is critical to achieving the vision of Codex as a proactive teammate. About the Role As we grow, we’re focused on turning Codex from a powerful individual tool into a production-grade teammate for entire organizations. You will work across internal OpenAI teams and external customers, from fast-moving startups to large enterprises, to make it possible to deploy, operate, and trust Codex in increasingly demanding real-world environments. As Codex’s consumer adoption accelerates, enterprise demand is growing just as quickly, and there is also increasing opportunity to expand Codex through ecosystem capabilities that unlock new workflows, integrations, and discovery. This team helps turn messy, real-world team requirements into robust, repeatable, and scalable product and

PythonAWSCI/CDRest
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s mission is to ensure that artificial general intelligence benefits all of humanity. A majority of our users interact with our products in languages other than English, and our products must work seamlessly across languages, regions, and cultures. The Internationalization team builds the infrastructure that enables OpenAI products to ship globally by default. We develop the systems that power localization, international product launches, and high-quality global user experiences across all OpenAI products. About the Role As a Senior Software Engineer on the Internationalization team, you will build the systems that power localization and international product launches at OpenAI. You’ll work on the platform that manages product content, translation workflows, and localization infrastructure across our products. This role sits at the intersection of AI systems, developer platforms, and product infrastructure. In this role, you will Build and scale OpenAI’s localization, content, and experimentation platform used across OpenAI product teams, including open-source components: Develop AI-powered translation pipelines combined with human-in-the-loop review workflows. Design systems that reliably deliver localized product content across web and mobile apps. Build tools that enable linguists and localization teams to review and improve translations. Develop developer tooling that simplifies localization and internationalization workflows. Build and maintain internationalization libraries used across OpenAI products: Design systems that correctly handle numbers, currencies, dates, and pluralization across locales. Improve support for multilingual interfaces and right-to-left languages. Partner with product teams to improve the international readiness of new features. You might thrive in this role if you Have strong software engineering experience building backend or full-stack systems. Have familiarity with Java, React, MySQL, and cloud infrastructure p

JavaReactSQLMySQL
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Applied team brings OpenAI’s technology to the world through products used by hundreds of millions of people and by developers and businesses building on our APIs. We work across research, engineering, product, policy, safety, and operations to deploy frontier AI systems responsibly and safely. The Trust & Safety Data Engineering team builds the data foundations that help OpenAI understand, detect, investigate, and mitigate abuse and safety risks across our products. We partner with Integrity, Investigations, Safety Systems, Product Policy, Privacy, Data Science, Engineering, and Data Platform to create reliable, privacy-safe datasets and pipelines for fraud and abuse detection, enforcement workflows, safety measurement, ML feature generation, launch readiness, and transparency reporting. About the Role We are hiring a Technical Lead Manager to lead and grow the Trust & Safety Data Engineering team. This is a hands-on leadership role for someone who can set strategy, shape data architecture, align senior stakeholders, coach engineers, and drive execution on high-impact data systems. You will help turn fragmented launch and incident support into durable, reusable, privacy-safe data foundations that Trust & Safety teams can rely on. The systems your team builds will help OpenAI detect risk, investigate abuse, power operational workflows, develop and evaluate safety models, measure interventions, support product launches, and report accurately on platform integrity. In This Role, You Will Lead and grow a high-performing Trust & Safety Data Engineering team. Define the roadmap and technical strategy for Trust & Safety data systems. Build canonical, privacy-safe datasets and pipelines for abuse detection, fraud detection, risk signals, enforcement, scaled review, transparency reporting, and safety monitoring. Create reusable foundations for Trust & Safety model development, including features, labels, training data, backtesting,

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