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Ai Systems Engineer in San Francisco

1,487 active opportunities · Updated October 2026

Explore current ai systems engineer jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the team The Intelligence and Investigations team seeks to rapidly identify and mitigate abuse and strategic risks to ensure a safe online ecosystem in close collaboration with our internal and external partners. Our efforts contribute to OpenAI's overarching goal of developing AI that benefits humanity. This role focuses specifically on AI Safety: understanding and mitigating risks created or amplified by increasingly capable AI systems. It is not a cybersecurity, information security, or corporate security role. The Strategic Intelligence & Analysis (SIA) team provides safety intelligence for OpenAI’s products by monitoring, analyzing, and forecasting real-world abuse, geopolitical risks, and strategic threats. Our work informs AI safety mitigations, product decisions, and partnerships, ensuring OpenAI’s tools are deployed responsibly across critical sectors. About the role We are looking for a Frontier AI Risks Lead to help us understand potential harms and misuse of AI in a time of rapid, sustained change. We seek to understand how developments in AI could intersect with misuse and abuse, accelerating existing harm areas and creating novel risks. We seek to scan available signals and use strategic foresight methodologies to enable proactive detection and mitigation of frontier AI risks. This is an AI safety role focused on frontier and systemic risks, including model misalignment, recursive self-improvement (RSI), multi-agent interaction, loss of control, runaway agents, and related emerging failure modes. In this role, you will help provide a strategic-level perspective on a range of frontier AI safety areas, producing actionable understanding of issues relevant to OpenAI’s platforms, systems, and broader mission. Utilizing mixed quantitative and qualitative methodologies, you will spot early warning signs, pull threads on potentially concerning behavior, and turn weak signals into clear, prioritized risk calls. You will focus on upstream ecosystem sc

AWSRestAIGo
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team Models are becoming increasingly capable—moving from tools that assist humans to agents that can plan, execute, and adapt in the real world. Mitigating the frontier risks resulting from these capabilities is paramount to OpenAI’s ability to continue deploying models safely. The Preparedness team is dedicated to addressing these critical risks. Our work includes: Measurement. Monitoring and predicting the evolving capabilities of frontier AI systems. Mitigation. Keeping misuse and misalignment safeguards, alignment tools, and security measures on track to adequately address extreme threats that might arise in the future. Coordination. Setting mitigation targets by maintaining OpenAI’s preparedness framework , and partnering with other staff to achieve these targets. This is urgent, fast-paced work that has far-reaching implications for the company and for society. About the Role We are seeking exceptional researchers who can push the frontier of safety mitigations. You will help derisk frontier models by developing novel safety mitigations, developing and applying new techniques from domains like interpretability, control, and alignment to ensure the safety of OpenAI’s deployed models. You will play a critical role in defining how a safe AI system should look in the future at OpenAI, making a significant impact on our mission to build and deploy safe AGI. This role requires strong technical depth and close cross-functional collaboration to ensure our safety mitigations are enforceable, scalable, and effective. We seek researchers who can partner with experts across domains such as misalignment, cybersecurity, and biology in order to develop the best possible end-to-end safety stack. In this role, you will: Work on identifying emerging AI safety risks and new methodologies for exploring and mitigating the impact of such risks Build (and then continuously refine) the evaluations that enable us to assess the extent of these risks; this might include worki

PythonAWSRestMachine Learning
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team The Safety Systems team is responsible for various safety work to ensure our best models can be safely deployed to the real world to benefit the society and is at the forefront of OpenAI's mission to build and deploy safe AGI, driving our commitment to AI safety and fostering a culture of trust and transparency. The Model Safety Research team aims to fundamentally advance our capabilities for precisely implementing robust, safe behavior in AI models, and to leverage these advances to make OpenAI’s deployed models safe and beneficial. This requires a breadth of new ML research to address the growing set of safety challenges as AI becomes more powerful and used in more settings. Key focus areas include how to enforce nuanced safety policies without trading off helpfulness and capabilities, how to make the model robust to adversaries, how to address privacy and security risks, and how to make the model trustworthy in safety-critical domains. We seek to learn from deployment and distribute the benefits of AI, while ensuring that this powerful tool is used responsibly and safely. About the Role OpenAI is seeking a senior researcher with passion for AI safety and experience in safety research. Your role will set directions for research to enable and empower safe AGI and work on research projects to make our AI systems safer, more aligned and more robust to adversarial or malicious use cases. You will play a critical role in shaping how a safe AI system should look like in the future at OpenAI, making a significant impact on our mission to build and deploy safe AGI. In this role, you will: Conduct state-of-the-art research on AI safety topics such as RLHF, adversarial training, robustness, and more. Implement new methods in OpenAI’s core model training and launch safety improvements in OpenAI’s products. Set the research directions and strategies to make our AI systems safer, more aligned and more robust. Coordinate and collaborate with cross-functional team

AWSRestMachine LearningAI
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team The Safety Systems team is responsible for various safety work to ensure our best models can be safely deployed to the real world to benefit the society, and is at the forefront of OpenAI's mission to build and deploy safe AGI, driving our commitment to AI safety and fostering a culture of trust and transparency. The Safety Oversight Research team aims to fundamentally advance our capabilities to maintain oversight over frontier AI models, and leverage these advances to ensure OpenAI’s deployed models are safe and beneficial. This requires a breadth of new ML research in the areas of human-AI collaboration, reasoning, robustness, and scalable oversight to keep pace with model capabilities. We invest heavily in developing novel model and system-level methods of identifying and mitigating AI misuse and misalignment. Our goal is to learn from deployment and distribute the benefits of AI, while ensuring that this powerful tool is used responsibly and safely. About the Role OpenAI is seeking a senior researcher with a passion for AI safety and experience in safety research. Your role will set directions for research to maintain effective oversight of safe AGI and work on research projects to identify and mitigate misuse and misalignment in our AI systems. You will play a critical role in defining how a safe AI system should look in the future at OpenAI, making a significant impact on our mission to build and deploy safe AGI. In this role, you will: Develop and refine AI monitor models to detect and mitigate known and emerging patterns of misuse and misalignment. Set research directions and strategies to make our AI systems safer, more aligned, and more robust. Evaluate and design effective red-teaming pipelines to examine the end-to-end robustness of our safety systems, and identify areas for future improvement. Conduct research to improve models’ ability to reason about questions of human values, and apply these improved models to practical safety challen

PythonAWSRestMachine Learning
O
📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -83.9%
Quick readStrong listing-quality and freshness signals

About the Team Our Safety Systems team is at the forefront of OpenAI's mission to build and deploy safe AGI, driving our commitment to AI safety and fostering a culture of trust and transparency. Within Safety Systems, the Model Policy team works to ensure that increasingly capable models behave safely and reliably in real-world environments. We investigate emerging model failures, define the behavior models should exhibit instead, and develop the data, evaluations, monitoring, and safeguards needed to improve and validate that behavior. Our work connects alignment research with the practical challenges of training and deploying frontier models. About the Role In this role, you will shape how OpenAI understands and addresses real-world risks that emerge from model misalignment as models become more autonomous and operate over longer horizons. You will investigate how misaligned behavior emerges across extended trajectories - including when models persist toward the wrong objective, take unsafe shortcuts, lose track of instructions, exploit weaknesses in their environment, or circumvent constraints - and translate these insights into behavioral policies, evaluations, monitoring, and safeguards. This role is ideal for someone who wants to turn alignment and safety concerns into concrete, empirically grounded improvements to frontier AI systems. Your Responsibilities: Identify vulnerabilities that emerge as models interact with tools, data, and external systems, and translate them into model- and system-level safeguards. Develop threat models and empirical frameworks for understanding harmful outcomes from misaligned behavior. Build frameworks for understanding harmful outcomes arising from model misalignment. Identify the underlying behaviors and system conditions that drive those outcomes. Turn findings into policy frameworks, evaluation criteria, online measurement and safeguards. Develop human data campaigns and gold sets to ground measurement and evaluation of eme

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the team Models are becoming increasingly capable—moving from tools that assist humans to agents that can plan, execute, and adapt in the real world. Mitigating the frontier risks resulting from these capabilities is paramount to OpenAI’s ability to continue deploying models safely. The Preparedness team is dedicated to addressing these critical risks. Our work includes: Measurement. Monitoring and predicting the evolving capabilities of frontier AI systems. Mitigation. Keeping misalignment safeguards, alignment tools, and on track to adequately address extreme threats that might arise in the future. Coordination. Setting mitigation targets by maintaining OpenAI’s preparedness framework , and partnering with other staff to achieve these targets. This is urgent, fast-paced work that has far-reaching implications for the company and for society. About the role Preparedness is hiring strong technical executors to support preparations for accelerated AI development, which may culminate in recursive self-improvement. This work relies on anticipating misalignment risks that might exist in the future, but might not exist now; so it’s especially important that people in this role are tasteful and strategic. The role is wide-ranging, covering any mitigation for loss of control risk, spanning the design and implementation of better pre-deployment risk-assessment , control measures , RSI-relevant training interventions, and turning one’s technical work into established institutional practices and external-facing communications. Below is a subset of our focus areas: Scalable oversight: Establishing practices for model misbehavior monitoring and oversight which remain effective in superhuman model capability regimes, with a focus on bridging from today’s monitoring approaches to future-proof ones. Automated auditing: As model capabilities increase, we’ll increasingly rely on automated approaches for finding the most severe forms of model misalignments. We’ll both need to s

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time· Remote
✓ Quality checkedCompany trend -83.9%

About the Team The Safety Systems team is at the forefront of OpenAI's mission to build and deploy safe AGI, driving our commitment to AI safety and fostering a culture of trust and transparency. The Model Policy team aligns model behavior with desired human values and norms. We co-design policy with models and for models by driving rapid policy taxonomy iteration based on data and defining evaluation criteria for foundational models’ ability to reason about safety. Key focus areas include: catastrophic risk, mental health, teen safety and multimodal safety. About the Role Providing access to frontier AI systems raises complex questions around dual-use science and catastrophic risk. How should models respond to requests involving chemical synthesis, biological experimentation, or pathogen research? Where is the boundary between legitimate scientific inquiry and information that could enable misuse? How do we design policies that meaningfully reduce risk without unnecessarily restricting beneficial research? This is a senior role in which you’ll help shape policy creation and development at OpenAI for addressing biological and chemical risks. You will develop structured policy frameworks and taxonomies to guide safe model behavior. This role sits at the intersection of biosecurity expertise, AI safety research, and policy design. You will help ensure that frontier AI systems can support beneficial life sciences research, such as drug discovery, public health, and biosafety, while reducing the risk that these capabilities could be misused. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you’ll: Design and maintain model policies governing chemical and biological risk, defining how models should safely handle dual-use scenarios. Develop structured taxonomies of chemical and biological risk that inform model training data, evaluation benchmarks, and safet

AWSGitRestAI
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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team Our Safety Systems team is at the forefront of OpenAI's mission to build and deploy safe AGI, driving our commitment to AI safety and fostering a culture of trust and transparency. The Model Policy team aligns model behavior with desired human values and norms. We co-design policy with models and for models by driving rapid policy taxonomy iteration based on data and defining evaluation criteria for foundational models’ ability to reason about safety. Key focus areas include: catastrophic risk, mental health, teen safety and multimodal safety. About the Role Providing access to frontier AI systems raises complex questions around dual-use science and catastrophic risk. How should models respond to requests involving chemical synthesis, biological experimentation, or pathogen research? Where is the boundary between legitimate scientific inquiry and information that could enable misuse? How do we design policies that meaningfully reduce risk without unnecessarily restricting beneficial research? This is a senior role in which you’ll help shape policy creation and development at OpenAI for addressing biological and chemical risks. You will develop structured policy frameworks and taxonomies to guide safe model behavior. This role sits at the intersection of biosecurity expertise, AI safety research, and policy design. You will help ensure that frontier AI systems can support beneficial life sciences research, such as drug discovery, public health, and biosafety, while reducing the risk that these capabilities could be misused. Our relevant publications: Preparedness framework Preparing for future AI capabilities in biology Safety evaluations hub OpenAI GPT5 System Card Evaluating Fairness in ChatGPT Improving Model Safety Behavior with Rule-Based Rewards OpenAI Model Spec Your Responsibilities: Design and maintain model policies governing chemical and biological risk, defining how models should safely handle dual-use scenarios. Develop structured taxonomi

AWSGitRestMachine Learning
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team OpenAI’s Industrial Compute organization is building the infrastructure required to support the next generation of frontier AI systems. Through a combination of strategic partnerships and self-built data center campuses, we are scaling the physical infrastructure needed to deliver compute at unprecedented scale. The Commissioning organization is responsible for ensuring this infrastructure is safely tested, validated, integrated, and transitioned into reliable operations. As the portfolio grows, the team is building common standards, processes, tools, and reporting systems that allow commissioning programs to operate consistently across projects while giving teams and leadership clear visibility into readiness, risk, and execution. About the Role We are seeking a Commissioning Program Manager to build and scale the operating systems behind OpenAI’s infrastructure commissioning programs. You will own the development and continuous improvement of commissioning standards, processes, tools, dashboards, and KPIs across the infrastructure portfolio. You will work closely with commissioning and construction teams to translate field execution needs into practical playbooks, workflows, templates, metrics, and reporting mechanisms that teams can use from construction readiness through testing and turnover. This role sits at the intersection of infrastructure delivery, program management, process design, and data. The ideal candidate understands how complex construction projects operate and can turn fragmented workflows and project data into repeatable systems that improve execution without creating unnecessary administrative burden. Key Responsibilities Develop and maintain commissioning program standards, playbooks, process maps, templates, checklists, stage gates, and acceptance criteria across infrastructure projects. Establish consistent workflows for commissioning planning, construction readiness, QA/QC, issue management, document control, testing evidence

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team Industrial Compute is building the infrastructure ecosystem that enables OpenAI to train and deploy increasingly capable AI systems at unprecedented scale. The organization operates across compute supply, demand, infrastructure, partnerships, and the physical and commercial systems required to make large-scale compute available. Industrial Compute Strategy & Operations serves as the connective operating layer across this ecosystem. The team works directly with senior leadership across Scaling, Finance, Partnerships, Research, and Infrastructure to translate ambiguous, high-impact challenges into clear strategies, scalable operating mechanisms, and decisive execution. This team is responsible for ensuring that OpenAI’s compute strategy evolves into durable competitive advantage by identifying systemic constraints, aligning stakeholders around critical decisions, and driving the operating mechanisms required to execute at scale. About the Role We are seeking a highly experienced Strategic Operations leader to help shape and operationalize OpenAI’s compute strategy across supply, demand, infrastructure, partnerships, and commercial strategy. This is a senior individual contributor role operating at the intersection of strategy, operations, infrastructure, and executive decision-making. You will work closely with compute leadership to identify the most consequential problems facing the organization, develop structured approaches to solving them, align stakeholders across the company, and drive initiatives from ambiguous concepts through execution. The role will span both strategic and operational work. You may develop long-range compute strategies and investment frameworks, evaluate build-versus-buy decisions, shape major commercial transactions, establish organizational planning mechanisms, or take ownership of a cross-functional initiative that does not have a clear organizational home. Success in this role requires exceptional judgment, analytical

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team The Preparedness team is an important part of the Safety Systems org at OpenAI, and is guided by OpenAI’s Preparedness Framework . Frontier AI models have the potential to benefit all of humanity, but also pose increasingly severe risks. To ensure that AI promotes positive change, the Preparedness team helps us prepare for the development of increasingly capable frontier AI models. This team is tasked with identifying, tracking, and preparing for catastrophic risks related to frontier AI models. The mission of the Preparedness team is to: Closely monitor and predict the evolving capabilities of frontier AI systems, with an eye towards misuse risks whose impact could be catastrophic to our society Ensure we have concrete procedures, infrastructure and partnerships to mitigate these risks and to safely handle the development of powerful AI systems Preparedness tightly connects capability assessment, evaluations, and internal red teaming, and mitigations for frontier models, as well as overall coordination on AGI preparedness. This is fast paced, exciting work that has far reaching importance for the company and for society. About the Role We’re hiring a Data Scientist to help build, evaluate, and continuously improve mitigations that prevent extreme harms from AI systems. This role is for an experienced, highly autonomous individual contributor who can take ambiguous problem statements, structure rigorous analyses, and translate findings into actionable product and policy changes. This position goes beyond “running evals.” You’ll help create mitigation intelligence and monitoring systems that enable OpenAI to detect issues early, measure effectiveness over time, and reduce both over-blocking (unnecessary friction) and under-blocking (missed harm). What You’ll Do Evaluate and improve mitigation systems, including classifiers and detection pipelines across domains (e.g., biosecurity, cybersecurity, and emerging risk areas). Diagnose false positives and fa

PythonSQLAWSRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team OpenAI’s Hardware organization develops system and infrastructure solutions optimized for advanced AI workloads. We collaborate across research, software, and external hardware partners to design and deploy next-generation AI systems at scale. Our team works closely with silicon vendors and system partners to evaluate emerging technologies, validate performance characteristics, and ensure that hardware capabilities translate effectively to real-world AI workloads. About the Role We are seeking a 3P Hardware Architecture Expert with deep expertise in GPU and accelerator architectures to engage directly with silicon vendors and guide hardware decisions for AI infrastructure. In this role, you will evaluate architectural tradeoffs across compute, memory, and interconnect systems, translating vendor specifications into real-world workload impact. You will play a critical role in early silicon evaluation, benchmarking, and performance validation, helping ensure that next-generation hardware meets the needs of our workloads. This role is highly hands-on and requires both deep technical understanding and the ability to engage at a high level with partners such as NVIDIA and AMD on architectural direction and design tradeoffs. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance. Key Responsibilities Engage deeply with silicon vendors (e.g NVIDIA & AMD) on GPU and accelerator architecture tradeoffs. Analyze and interpret performance, power, and efficiency characteristics of next-generation hardware. Translate vendor specifications into expected real-world performance for AI workloads. Evaluate architectural aspects including: compute throughput and utilization memory systems (HBM, cache hierarchies, bandwidth constraints) data types and precision tradeoffs (FP16, BF16, FP8, etc.) interconnect and scaling behavior. Run benchmarks and profiling to validate hardware performance a

AWSRestAIRust
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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -83.9%
Quick readStrong listing-quality and freshness signals

About the role As a Pricing Strategist focused on GTM, you will help shape pricing strategy for B2B enterprise customers across our product portfolio. Working within Finance and partnering with GTM, Sales, and Product, you will focus on pricing analytics, price performance, and the effectiveness of credit programs while contributing to broader commercial strategy. In this role, you will Build regular pricing-performance reviews, analyze discounting and concessions, and turn findings into better pricing guidance. Develop commercial strategies and pricing programs for customer segments such as education, startups, and government. Define objectives and success measures for credit programs and promotions, and evaluate their return on investment. Translate segment goals and product pricing strategy into scalable pricing frameworks and commercial structures. Partner on strategic enterprise deals to align commercial proposals with sound deal economics and pricing strategy. You might thrive in this role if you Approach problems from first principles, identify root causes, and develop clear options for stakeholders. Work effectively through ambiguity and differing perspectives. Understand how sales organizations operate and collaborate well across GTM strategy, Finance, and Product. Bring relevant experience from consulting, strategy and operations, or pricing, particularly work involving analytical teams. Experience with pricing analytics, pricing frameworks, discounting guardrails, or new-product pricing is helpful, but a strictly pricing-specific background is not required. About OpenAI OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We push the boundaries of the capabilities of AI systems and seek to safely deploy them to the world through our products. AI is an extremely powerful tool that must be created with safety and human needs at its core, and to achieve our mission, we mu

Artificial IntelligenceAIFinance
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team OpenAI’s Hardware organization develops system and infrastructure solutions designed for the unique demands of advanced AI workloads. We work closely with research, software, and external hardware partners to shape the next generation of AI systems, from silicon through full-scale deployments. Our team focuses on understanding and optimizing performance across the full system stack—ensuring that architectural decisions are grounded in rigorous, quantitative analysis of real-world workloads. About the Role We are seeking a Performance Modeling Lead to build and lead a small, high-impact team responsible for answering forward-looking architectural questions across AI infrastructure systems. You will develop modeling frameworks and methodologies to evaluate system-level tradeoffs and guide key design decisions. Your work will directly influence reference architectures, vendor designs, and long-term infrastructure strategy. This role sits at the intersection of AI workloads, system architecture, and quantitative modeling, and requires strong technical judgment, ownership, and the ability to translate complex analysis into clear, actionable guidance. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance. Key Responsibilities Build and own a performance modeling framework/toolchain to evaluate AI systems across multiple levels of abstraction. Analyze and quantify architectural tradeoffs across compute, memory, networking, storage, and system topology. Develop performance models to guide decisions on: scale-up vs. scale-out architectures interconnect and network design memory hierarchy and system balance. Translate modeling outputs into clear recommendations for internal teams and external hardware vendors. Influence reference designs and vendor roadmaps through data-driven insights. Partner closely with machine learning, systems, and hardware teams to understand workload characte

AWSRestMachine LearningAI
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team OpenAI’s mission is to ensure that artificial general intelligence benefits all of humanity. Customer Education plays an important role in that mission by helping people and organizations use increasingly capable AI systems effectively, responsibly, and with confidence. We help customers build the confidence and practical skills to use OpenAI effectively, change how work gets done, and realize lasting value. About the Role Helping organizations adopt AI takes more than access to powerful technology. People across the workforce need the skills and confidence to use it well. Within Customer Education, you will lead the enterprise learning program and team. You will set direction, develop the team, and build a clear, high-quality learning portfolio that moves customers from first learning to confident use and meaningful business impact. This is a rare opportunity to define how customers learn with OpenAI at global scale, alongside the teams shaping the technology. In this role, you will: Lead and develop a high-performing Customer Learning team. Own the customer-facing Learn experience, curriculum, and program portfolio—from strategy through results. Turn priority customer needs into role-based tracks, paths, and high-quality programs. Make the portfolio easy to understand, with clear starting points, progression, and relationships among experiences. Lead how learning reaches customers through owned and partner channels. Use customer and product evidence to measure impact and decide what to build, scale, improve, defer, or stop. You might thrive in this role if you: Build strong teams, grow talent, and create accountability. Shape education strategy from customer needs and turn it into programs with measurable impact. Make clear portfolio choices about investment, capacity, and focus. Turn complex learning into clear journeys customers can understand and use. Reach customers through owned and partner channels, building trust across teams. Qualifications

AWSGitRestAI
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