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Ai Systems Research And Development Engineer in Massachusetts

37 active opportunities · Updated October 2026

Explore current ai systems research and development engineer jobs in Massachusetts. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 Massachusetts, United States
✓ High-confidence listingCompany trend +671.4%

$60.2K – $100.4K/yr

Quick readStrong listing-quality and freshness signals

Use Your Power for Purpose At Pfizer, our purpose is to deliver breakthroughs that change patients’ lives. In this role, you will contribute to the discovery and advancement of innovative medicines for patients worldwide by applying rigorous science, modern pharmacology, and cutting-edge technologies. Your work will help transform promising therapeutic ideas into high-quality experimental data that enable confident decisions across the drug discovery process. What You Will Achieve A key strategic focus within the Internal Medicine Research Unit (IMRU) is the discovery of novel therapies for obesity, cardiovascular disease, and related cardiometabolic conditions. As an Associate Scientist in the In Vitro Pharmacology group, you will contribute to early drug discovery programs by generating rigorous, reproducible pharmacology data that support target validation, assay development, compound profiling, and mechanism-of-action studies. This role is well suited for a collaborative, hands-on scientist with experience in cell-based assay execution, mammalian cell culture, quantitative data analysis, and an interest in receptor pharmacology within cardiometabolic drug discovery. How You Will Achieve It Develop, optimize, and execute cell-based signaling, ligand-binding, and other in vitro pharmacology assays to generate high-quality data that support project decisions. Support compound profiling and mechanism-of-action studies through careful experimental design, troubleshooting, and quantitative data analysis. Maintain mammalian cell cultures and prepare fit-for-purpose cellular or membrane-based assay reagents to support screening, binding, and functional assay workflows. Apply core pharmacology concepts, including ligand potency, efficacy and affinity to interpret experimental results. Work collaboratively with pharmacology colleagues and cross-functional pr

AIExcelRecruitment
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📍 Massachusetts, United States
✓ High-confidence listingCompany trend +671.4%

$99.2K – $165.4K/yr

Quick readStrong listing-quality and freshness signals

Why Patients Need You Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world. What You Will Achieve As part of the Comparative Medicine team, you will support the Research & Development site by managing a vivarium to deliver flawless animal care and welfare and will assure the quality of care and the animal facility environment is in compliance with local regulations and AAALAC International guidelines partnering with Research and Development Research Units and Partner lines to facilitate study support. It is your hard work along with innovative ideas and focus that will help in making Pfizer ready to achieve new milestones and help patients across the globe. How You Will Achieve It Assure that the care and welfare of laboratory animals is provided in compliance with local regulations and AAALAC International guidelines. Manage and engage animal care and technical staff in the pursuit of flawless animal care and welfare by ensuring adherence to established policies and procedures. Support the career and personal development of the animal care and technical staff. Assist with a centralized CM training program for research animal care and use for animal care staff, principal investigators and research technicians throughout WRD. Participate in the direction of a centralized CM program of occup

AIRecruitment
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📍 Massachusetts, United States
✓ High-confidence listingCompany trend +671.4%

$139.1K – $231.9K/yr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY Exciting opportunity in Clinical Pharmacology! Our Clinical Pharmacology Team is looking for an Associate Director to support the exciting portfolio in Internal Medicine. Our team members champion the innovative use of MIDD for efficient drug development and robust decision-making. A great environment for learning and professional growth! Our Clinical Pharmacology Leads have key roles to play in influencing the discovery and development of drugs. Pfizer is a leader in model informed drug discovery and development (MIDD), and we are expanding in influence and impact. We have an open position as Clinical Pharmacology Lead supporting our End-to-End Internal Medicine portfolio. The ideal candidate is responsible for providing the clinical pharmacology and MIDD components of clinical plans and provide clinical pharmacology expertise to the project team and regulatory interactions. Working with multifunctional study team, Clinical Pharmacology Leads utilize innovative methods to integrate knowledge of pharmacokinetics, pharmacodynamics, patient characteristics and diseases for rational development strategies and decisions, as well as optimal study designs and dosage regimen selections. ROLE RESPONSIBILITIES Act as Clinical Pharmacology representative on Clinical Sub Team and Development Team and other multifunctional teams as appropriate. Responsible for providing expertise, leadership, and deliverables of clinical pharmacology for the assigned projects within sphere of influence. Design and execute clinical pharmacology plans and implement clinical pharmacology best practices on project teams. Work closely with other disciplines to ensure that sufficient preclinical PK/PD knowledge exists to underwrite safe human administration and to establish the structure of a predictive model prior to FIH. Responsible for planning and overseeing clinical pharmacolo

AIRecruitment
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📍 Massachusetts, United States
✓ Quality checkedCompany trend +671.4%

$162.9K – $271.5K/yr

ROLE SUMMARY: The key strategic focus within the Internal Medicine Research Unit (IMRU) is identifying novel therapies to prevent or treat metabolic diseases such as obesity and cardiovascular disease. Our goal is to build a world-class research team of dedicated scientists committed to developing a deep mechanistic understanding of the metabolic pathways underlying disease pathogenesis. As a senior scientific leader and member of the obesity discovery biology team, this individual will play a significant role in shaping the scientific direction for the obesity therapeutic area and influencing broader IMRU research strategy and portfolio priorities. The individual will help create and drive discovery research strategy across multiple programs, including target ideation, validation, translational biomarker strategy, hypothesis testing, and early clinical development within the IMRU obesity portfolio. The successful candidate will lead through both direct team leadership and influence across multidisciplinary partners, helping align scientific decisions across discovery biology, translational sciences, clinical, computational, and external collaborators. The individual will identify emerging therapeutic opportunities, advance portfolio programs with scientific rigor and urgency, and represent research strategies to internal leadership and the external scientific community. Knowledge and experience in the study of metabolic pathways are essential, and familiarity with the pathophysiology of dysmetabolic states would be advantageous. Strong self-motivation, excellent communication and interpersonal skills, and the ability to lead, mentor, and build scientific capability in a highly collaborative environment are essential. ROLE RESPONSIBILITIES: Shape and influence the scientific direction for discovery research programs aligned with IMRU therapeutic area and portfolio strategy. Ap

AIRecruitment
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📍 Massachusetts, New York, United States· Full-time
✓ High-confidence listingCompany trend -83.5%

From $100K/yr

Quick readStrong listing-quality and freshness signals

Our SLED sales team works with a best-of-breed product that solves real problems for our customers. Sellers follow a well-defined methodology that helps them identify the customer's unique needs and clearly convey the value of the Datadog product. Whether you're looking to learn from the best or be the best, the Datadog sales team is dedicated to furthering personal development and team success. We are searching for an experienced SLED Sales Executive that has a real passion for technology and can deliver on bold revenue targets. As we continue to enter into bigger markets, and formalize our support for the Public Sector enterprise segment, this division within Datadog will blaze the path for organizational growth. This is a lucrative opportunity to break into new State, Local, and Education accounts within a rich territory, as well work with accounts who are in a hybrid state and transitioning to the cloud. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Prospect into large State, Local, and Education organizations while running an efficient sales process Maintain, build and own specific relationship maps for your territory including existing relationships and aspirational contacts Develop a deep comprehension of customer's business Negotiate favorable pricing and business terms with large SLED enterprises by selling value and ROI Handle existing customer expectations while expanding reach and depth into assigned territory Demonstrate resourcefulness when faced with challenges that defy easy solution Have intuitive sense of necessary steps to close business and gain customer validation Identify robust set of value drivers behind all opportunities Ensure high forecasting accuracy and consistency Who You Are: Someone with 5+ years closing expe

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📍 Massachusetts, California, United States· Full-time
✓ High-confidence listingCompany trend -83.5%

From $173K/yr

Quick readStrong listing-quality and freshness signals

We are seeking a Head of Executive Search to build and lead a centralized, specialized function responsible for global leadership hiring across sales, marketing, technical solutions, and G&A. This role will bring consistency, rigor, and strategic ownership to Senior Director, VP, and SVP hiring while partnering closely with executive stakeholders to deliver high-impact talent outcomes. You will elevate assessment and decision-making practices, develop proactive executive talent pipelines, and generate market intelligence that informs hiring and organizational strategy. This is a high-visibility opportunity to shape how Datadog attracts, evaluates, and hires senior leadership globally, with potential to expand scope to Director+ and executive-level searches over time. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Own end-to-end strategy and execution for Senior Director, VP, and SVP searches, with dotted line to APAC Recruit highly confidential searches end to end, taking on execution responsibilities when needed Build and lead a specialized executive search team, including defining operating rhythms and performance expectations Establish and operationalize a standardized leadership hiring playbook, including executive assessment frameworks, confidentiality protocols, and stakeholder governance Partner directly with C-suite, VP, and SVP stakeholders to drive alignment, calibration, and high-quality hiring decisions Develop proactive, long-term pipelines for critical leadership roles while producing market intelligence to inform talent and organizational strategy Define and execute an agency engagement and executive candidate closing strategy to reduce external spend and deliver a high-touch candidate experience Who You Are: Expe

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📍 Massachusetts, New York, United States· Full-time
✓ High-confidence listingCompany trend -83.5%

From $98K/yr

Quick readStrong listing-quality and freshness signals

You will have the opportunity to shape, mold, and impact how fast we grow, the way we’re viewed, and the candidate experience. We are looking to hire a Recruiter who will be responsible for finding the best talent; you will be the face of recruiting at Datadog! You will be the first point of contact for new candidates in the hiring process, playing a critical role in identifying great candidates, telling the Datadog story and ultimately turning great candidates into great employees. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Find qualified talent for our open roles via sourcing, job posts, referrals, and agencies Screen candidates to ensure their qualifications match the open roles Collaborate with leadership to design or streamline interview processes Ensure follow up and closure for all interviewed candidates Negotiate compensation with qualified candidates Enhance our recruitment process through training interview teams Leverage Greenhouse to track candidate progress through funnel, resurface existing talent, and keep consistently clean data for reporting Ensure candidates have an excellent interview experience - regardless of outcome Who You Are: Experienced in full-lifecycle recruiting, with 5+ years either in-house or in a staffing agency environment A sourcing master in your ability to identify where top talent lives Autonomous with a demonstrated ability to work independently and simultaneously on multiple positions Exceptional at selling value proposition, negotiating and closing great candidates Skilled at operating with a sense of urgency in all stages of the recruiting cycle Able to successfully navigate an ever-changing process Datadog values people from a

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📍 Massachusetts, New York, United States· Full-time
✓ High-confidence listingCompany trend -83.5%

From $152K/yr

Quick readStrong listing-quality and freshness signals

The Manager of Networking at Datadog leads the global management of network services across all Datadog offices worldwide. This role is responsible for ensuring seamless, high-performance Wi-Fi and direct internet access in our global offices and conference room technology, supporting a rapidly growing global enterprise. As Datadog continues to grow rapidly, this role plays a critical part in scaling both the team and network infrastructure to meet increasing demand. This is a hybrid role that sits in global headquarters in New York city and requires three days in the office each week with occasional travel to our offices around the world. What You’ll Do: Lead the global network engineering teams, managing both full-time employees and third-party vendors to ensure consistent and high-quality service delivery for Datadog offices worldwide. Oversee the design, deployment and scaling of office network infrastructure, including Wi-Fi (Cisco Meraki) and edge networking devices (Cisco, Palo Alto, Juniper, and others), ensuring these services operate according to Datadog's defined service level objectives. Define and implement standards, policies, and processes for network infrastructure to ensure security, reliability and scalability. Collaborate with IT Security, Enterprise Technology, and Workplace teams to align network services with broader IT and business objectives. Develop and track operational metrics for service availability, network performance, driving continuous improvement and optimization. Who You Are: An experienced people manager with at least 5+ years of leadership experience managing teams of network engineers. Proven expertise in Wi-Fi network engineering, including deep knowledge of Cisco Meraki and edge networking solutions from vendors like Cisco, Palo Alto and Juniper. Experience managing large-scale office technology projects in global enterprises with more than 10 offices and 7,000+ employees, ensuring infrastructure keeps pace with ra

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📍 Massachusetts, California, United States· Full-time
✓ High-confidence listingCompany trend -83.5%

From $211K/yr

Quick readStrong listing-quality and freshness signals

We are Datadog's in-house product experts. The technical solutions team enables Datadog's worldwide growth by educating potential clients and ensuring that existing customers are happy and successful. The Product Solution Architecture team works closely with Datadog customers, Datadog’s Product management, engineering and Tech Solutions teams to help architect and implement the Datadog Solution. The team has grown to cover more than 12 Product Categories and needs a highly motivated, results-oriented individual to help lead the team. At Datadog, we place value in our office culture - the relationships and collaboration it builds, and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Manage a team of expert individual contributors, working with Engineering and Product Management on their Product, who help create best practices for adoption of Datadog at scale. Assist in recruiting and hiring of top talent for the team. Mentor/coach new hires during on-boarding to ensure proper ramping of skills and capabilities Ensure that your team is aligned to top company initiatives and enabled to work with various Datadog internal and external stakeholders Deliver performance reviews along with collaborating on and executing individual development plans Be a Trusted Advisor to Product Management by providing high quality feedback based on your field experience working closely with our Sales, Support, Partners and Customers Offer guidance on architecture choices, data collection, and best practices to large Enterprise customers as they adopt these Datadog services across the organization Participate in Executive Brief conversations with high profile customers and prospects about overall architecture, Observability Best Practices and industry trends Who You Are: 10+ years of experience solving complex problems for customers and a strong kno

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📍 Massachusetts, New York, United States· Full-time
✓ High-confidence listingCompany trend -83.5%

From $131K/yr

Quick readStrong listing-quality and freshness signals

Senior Partner Program Manager - Datadog Reseller Program Remote (US) or New York, New York, USA We're looking for an experienced Senior Partner Program Manager to own partner pricing strategy, partner deal support, and pricing enablement across Datadog's Channels & Alliances organization. In this role, you'll serve as the subject matter expert for partner pricing, helping shape how Datadog structures, operationalizes, and scales partner pricing across its ecosystem. You'll act as the primary liaison between Channels & Alliances and Deal Desk, ensuring partner-specific pricing requirements, commercial frameworks, and program considerations are represented in Datadog's broader pricing strategy and processes. You'll support both internal teams and external partners by providing guidance on pricing models, deal structures, incentives, and commercial programs. You'll also own pricing enablement for the partner organization, developing training content and onboarding programs that help Partner Sales Managers confidently navigate Datadog's evolving pricing landscape. This is a highly cross-functional role that requires deep experience with Deal Desk, partner commercial models, and SaaS pricing, along with the ability to translate complex pricing concepts into scalable programs, tools, and training. At Datadog, we place value in our office culture—the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You'll Do Own global partner pricing for the Datadog Partner Network Serve as the Channels & Alliances subject matter expert for partner pricing, commercial frameworks, and deal strategy Act as the primary liaison between Channels & Alliances and Deal Desk for partner-related pricing, discounting, incentives, and program requirements Advise Partner Sales Managers (PSMs) and partners on pricing models, deal structure

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📍 Massachusetts, California, United States· Full-time
✓ High-confidence listingCompany trend -83.5%

From $238K/yr

Quick readStrong listing-quality and freshness signals

Datadog is looking for a visionary Senior Leader of Sales Engineering (SE) to lead and scale a high-performing team of SE Directors in North America across Enterprise, Majors, and Public Sector accounts. This is a strategic leadership role with regional and global impact. You will define the Sales Engineering strategy for North America and act as a regional voice in global discussions with Product Management, Engineering, and Go-To-Market teams—ensuring that customer needs in North America influence Datadog’s global direction. At Datadog, we place value in our office culture - the relationships and collaboration it builds, and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You Will Do Executive Leadership & Organizational Growth Recruit, develop, and lead a team 3rd line SE Directors, fostering a culture of technical excellence, customer-centricity, and continuous growth. Define and drive the technical sales strategy across North America, and globally. Set the vision, priorities, and operating model for Sales Engineering, ensuring alignment with Datadog’s business objectives and local market dynamics. Partner with Sales Leadership to align on revenue targets, go-to-market initiatives, and strategic customer engagement across the region. Represent North America Sales Engineering globally, ensuring regional perspectives and requirements are reflected in Datadog’s product roadmap and GTM planning. Customer Partnership & Advocacy Act as a trusted advisor to C-level and senior technical executives, demonstrating how Datadog solves critical observability, performance, and security challenges, especially given the rapid business adoption of AI. Provide executive support for high-stakes opportunities, offering guidance throughout complex sales cycles. Serve as an executive sponsor for strategic customers across North America. Promote value-based technical s

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📍 Massachusetts, New York, United States· Full-time
✓ High-confidence listingCompany trend -83.5%

From $143K/yr

Quick readStrong listing-quality and freshness signals

We’re building the Compensation functions with the People team to scale with and support one of the fastest growing companies in tech. We're experiencing tremendous growth worldwide, and you will be key to incentivizing and rewarding employees on this exciting path. As one of the first people in an emerging function, you have a unique opportunity to put your stamp on the role and set the path for the future. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Collaborate closely with global business recruiting team on offers in real time as a trusted advisor Consult with and influence HR Business Partners, Recruiting, and Managers + Leadership to help drive compensation decisions and strategy critical for our Go To Market functions (sale, marketing) Use external data and a strong understanding of our business, maintain a competitive and current job catalog for all of our Technical Solutions and General & Administration teams Provide regular updates on industry trends and best practices, especially with respect to stock, to help ensure our overall Compensation strategy is highly competitive Partner with compensation colleagues to support the compensation team’s internal data gathering, modeling, analytics, reporting, and insights, using recruiting intelligence, manager knowledge, and benchmarking surveys to make sure our compensation approach is market-leading, scalable, and internally aligned Identify when our standard program is not meeting the needs of the business and proactively suggest improvements Who You Are: Experience in 5+ years of Compensation work, with expert-level understanding of compensation survey data and providers, and industry best practices You have supported technical solutions and/or general administrati

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📍 Massachusetts, United States
✓ High-confidence listingCompany trend +671.4%

$93.6K – $156K/yr

Quick readStrong listing-quality and freshness signals

What You Will Achieve A Senior Scientist (R 4 ) position is available in the Upstream Process Development group within the Bioprocess R&D organization. The successful applicant will join a team of scientists and engineers focused on developing and optimizing manufacturing processes for recombinant proteins and other modalities for early- and late-phase human clinical trials. In this role, the candidate will be responsible for designing and executing laboratory experiments in bench-top bioreactors and associated scale-down equipment with the goal of developing robust, scalable, and high productivity processes. The work will also involve collaborating with pilot, clinical, and commercial production facilities to ensure accurate technology transfer, successful large-scale production and associated regulatory filing activities. The candidate may also be involved in cutting edge technology development projects that seek to improve production processes and control strategies leveraging various process analytical technologies. How You Will Achieve It Design and execute

PythonAIRecruitment
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📍 Massachusetts, New York, United States· Full-time
✓ High-confidence listingCompany trend -83.5%
Quick readStrong listing-quality and freshness signals

Datadog is looking for a Senior Product Manager to help lead the evolution of our fleet and lifecycle management capability, the product surface that gives customers visibility into, and control over, the observability software running across their infrastructure. This capability manages the deployment lifecycle for core observability agents and OpenTelemetry collectors running on customer hosts and containers. The Senior PM will expand the scope of fleet capability to additional Datadog software components, making it the single place customers go to see everything running in their environment, at any version, in any deployment model, and to manage it remotely and safely at scale, for both human operators and, increasingly, AI agents acting on their behalf. This is a high-visibility, cross-functional role. You'll partner with multiple engineering teams and be responsible for defining and delivering a coherent, unified fleet experience across UI, API, and MCP for customers. At Datadog, we place value in our office culture - the relationships and collaboration it builds, and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You'll Do Own and evolve the product vision and roadmap for a unified fleet and lifecycle management capability spanning multiple product lines and deployment models. Define what "managed" means for each new software component as it's brought into fleet, balancing consistency of experience with the realities of each component's operational model. Drive a phased expansion plan, sequencing new components into fleet based on customer value, technical complexity, and dependency readiness. Partner closely with engineering leads across several teams to align on shared architecture principles to support disparate software components. Represent the voice of the customer for a capability that must work equally well for human operators using a UI and for AI

KubernetesAIGoRust
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📍 Massachusetts, New York, United States· Full-time
✓ High-confidence listingCompany trend -83.5%

From $960K/yr

Quick readStrong listing-quality and freshness signals

Datadog is seeking a Payroll Specialist to keep up with our rapidly growing company. As a Payroll Specialist, you will support the US payroll process for over 3000 employees. Direct responsibilities will include facilitating the semi monthly payroll for salaried exempt and nonexempt employees. The Payroll Specialist will review accuracy and partner closely with senior team leads to ensure payrolls are processed in a timely fashion. You will also be responsible for providing administrative support across our Canada, and Latin America population. Most importantly, you will collaborate with our People and Finance teams to continue to scale this important function. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do Partner with payroll team stakeholders to analyze data entry feeds while also supporting the semi-monthly payroll process from start to finish, ensuring employees are paid correctly and on time within our Workday payroll module. Understand the US payroll function and process payroll according to internal accounting principals and regulatory requirements. Process new hires, terminations, status changes, tax changes, domestic and international transfers, 401k contribution feeds and changes, timesheet data, compensation changes, employee personal information changes, retroactive adjustments, garnishments and supplemental payments entered into Workday HRIS. Resolve payroll discrepancies by running and analyzing Workday data reports. Directly involved in processing of equity transactions inclusive of restricted stock units (RSU), non-qualified stock options (NSO), incentive stock options (ISO), disqualified dispositions and all other equity related transactions. Collaborate with Finance stakeholders to support audits, identify and

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