Jobs in United States

Lead Enterprise Systems Engineer in United States

2,556 active opportunities · Updated October 2026

Explore current lead enterprise systems engineer jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

PE
📍 Florham Park, New Jersey, United States· Full-time· Hybrid
✓ Quality checked

Shape the Future with Dun & Bradstreet At Dun & Bradstreet, we believe data has the power to create a better tomorrow. As a global leader in business decisioning data and analytics, we help companies worldwide grow, manage risk, and innovate. Since 1841, businesses have trusted us to turn uncertainty into opportunity. We’re a diverse, global team that values creativity, collaboration, and bold ideas. Are you ready to make an impact and help shape what’s next? Join us! Explore opportunities at dnb.com/careers. We are seeking a highly skilled Senior Incident Response Analyst to lead advanced threat detection, investigation, and remediation efforts within our Security Operations program. This role is responsible for handling complex security incidents, guiding junior analysts, improving detection capabilities, and strengthening our overall security posture. The Senior Incident Response Analyst brings deep technical expertise, strong analytical thinking, and a proactive mindset toward defending the enterprise.

C
📍 Field Texas, United States
✓ Quality checkedCompany trend +340.2%

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Position Summary **Qualified candidates will sit in either Texas or Atlanta, Georgia area due to book of business** The NAT Accounts Senior Director of Account Management leads a team of Account Executives supporting large, complex National Accounts. This leader is responsible for customer retention, profitable growth, client satisfaction, account strategy, and effective execution across an assigned portfolio. The Senior Director partners with Sales, Client Management, Underwriting, Operations, Network, Clinical, Product, and other enterprise teams to address customer needs, manage business risks, and deliver measurable value. The role requires strong healthcare-industry knowledge, sound business judgment, executive-level communication, and the ability to lead through a complex organization. **In addition to a base salary, this opportunity is eligible for Sales Incentive Compensation + Stock options* * What you will do Lead, coach, and develop a high-performing team of Account Executives. Establish clear priorities, performance expectations, and accountability across the team. Oversee customer strategies focused on retention, growth, financial performance, member experience, and client satisfaction. Identify customer and portfolio risks early and lead the development of mitigation plans. Build

TN
📍 New York, NY, United States
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

The mission of The New York Times is to seek the truth and help people understand the world. That means independent journalism is at the heart of all we do as a company. It’s why we have a world-renowned newsroom that sends journalists to report on the ground from nearly 160 countries. It’s why we focus deeply on how our readers will experience our journalism, from print to audio to a world-class digital and app destination. And it’s why our business strategy centers on making journalism so good that it’s worth paying for. About the Role: The New York Times is looking for a Director, HR Business Partner for the Product Engineering and Technology groups to support and partner with the Chief Technology Officer, leaders, managers and employees across the technology function, and with our Chief Product Officer. You will manage a team of two, while also supporting employees directly. You will report to the VP, HR Business Partners. The Director, HRBP plays a critical role in driving a people strategy aligned with enterprise goals. You will be the primary HR partner to support our Chief Technology Officer (CTO), Chief Product Officer (CPO), managers, and employees of the technology organization - including guidance, management of the performance enablement cycle, and oversight of process/HR administration. This is a hybrid role based in our New York City headquarters. You can expect to come into the office 3+ days per week. Responsibilities: Be an advisor, partner, and coach to senior leaders, managers, and individual contributors across our Technology group, including the Chief Technology Officer and Chief Product Officer Lead and develop a team of two HR Business Partners to manage multiple HR issues and support the business Provide daily support to senior-level department leaders, managers, and employees, providing coaching, management of employee lifecycles and performance management, and oversight of process/HR administration Lead planning, communication

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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 New York, New York City, United States
✓ High-confidence listingCompany trend +68.8%

$33 – $55/hr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY Pfizer Commercial Oncology is introducing the world to the next era of cancer care. With a growing portfolio of novel therapies, industry-leading R&D, and a goal of delivering eight breakthroughs by 2030 across major cancer types, we're translating cutting-edge science into market-shaping impact. Here, you'll partner with exceptional colleagues across scientific, medical, and manufacturing teams, backed by advanced digital and AI-enabled infrastructure and the authority to accelerate medicines from discovery to delivery. Guided by our values of courage, excellence, equity, and joy, you'll have the opportunity to stretch your skills and build a career that evolves with you—across teams, roles, and the Pfizer enterprise. Join us to make history — for patients, for their families, for the future. At Pfizer Oncology, we are committed to “Outdo Cancer” by advancing transformative medicines wherever we can make a profound difference in the lives of patients. Today, Pfizer Oncology has an industry leading pipeline that includes the combined legacy Pfizer and Seagen portfolio across breast, genitourinary (GU) including both prostate and bladder, hematology-oncology and thoracic therapeutic areas. The primary purpose of this position will be to provide comprehensive day-to-day administrative support to the US Prostate Franchise Lead and to support the overall Franchise business. The Administrative Assistant will report to the US Prostate Vice President. In this role, the Administrative Assistant will be responsible for (but not limited to) heavy calendar management, coordination of meetings and events, development of agendas and meeting reports, slide development for select meetings, and requests and assembly of briefing materials, arranging travel and expense report preparation. As a working professional, he/she will be expected to handle tasks independently and in a proactive manner. <

AIExcelLogisticsRecruitment
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📍 New York, New York, United States
✓ High-confidence listing

$130K – $160K/yr

Quick readStrong listing-quality and freshness signals

CLEAR is building THE secure identity company of the future. Our mission is to make experiences safer and easier—physically and digitally. With more than 43 million Members and a growing network of partners across the world, CLEAR's secure identity platform is transforming the way people live, work, and travel. Whether it’s at the airport, stadium, or throughout your everyday life, CLEAR unlocks the magic of frictionless experiences. As a Sales Engineer II, you will be responsible for ensuring our customers successfully integrate with the CLEAR1 platform, with a focus on our Healthcare vertical. You will work across the Growth, Product, and Engineering teams to develop a deep understanding of the problems our customers are facing and influence how we’re building our platform for scale. We’re looking for a candidate with an excellent technical background who is looking to have a direct impact on customer and developer experiences. What you'll do: Lead presales customer engagements, including technical discovery, product demos, use case demos, RFPs, solution and integration scoping, and proof-of-concepts Drive customer integration for enterprise-level customers including building reference applications, prototypes, and architecture diagrams Develop code samples, integrations, and applications to demonstrate best practices and minimize customer development time, across a variety of languages and frameworks Support customers throughout the presales, proof of concept, and integration processes, assisting with common coding issues and patterns or troubleshooting Creating and maintaining public and internal documentation to help scale the team Act as the internal and external expert in the integration and usage of the CLEAR identity platform Collaborate across Sales, Product and Engineering to ensure that CLEAR strategically incorporates customer feedback and new product features into our roadmap Stay up-to-date with the latest trends and developments in the Healthc

C
📍 Buffalo Grove, United States
✓ Quality checkedCompany trend +340.2%

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Role Summary At CVS Health®, you’ll be working with a team of passionate colleagues who care deeply, innovate with purpose, hold themselves accountable and prioritize safety and quality in everything we do. Do you enjoy innovation while having fun doing it? If the answer yes, then this role might be for you! Join us and be part of something bigger, innovative and simplification in healthcare. We are seeking a highly experienced and innovative Principal (Director Level) Software Development Engineer to lead the application architecture, design, development, delivery of next-generation digital applications (including Reporting and financial solutions), and optimization of scalable, secure, and high-performance solutions leveraging AI across all major cloud platforms (AWS, Azure, and GCP). This role requires deep technical expertise, AI-enabled solutions, strategic thinking, scalable digital platforms, and enterprise integrations that power critical healthcare and pharmacy experiences and a passion for driving excellence in software engineering practices. This is a senior technical leadership role for a hands-on engineer who can operate across the full stack—from intuitive front-end applications to resilient backend services—while setting architectural direction, influencing engineering standards, and mentoring teams. The ideal candidate combines deep technical expertise, platform thin

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📍 Purchase, New York, United States
✓ Quality checkedCompany trend +212.5%

Our Purpose Mastercard powers economies and empowers people in 200&#43; countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential. Title and Summary Director, Office of Transformation Process Redesign Overview The Transformation Team leads strategic change initiatives to reimagine how Mastercard works and scales, simplifies, and accelerates business outcomes. The team partners across leadership, product, technology, and operations to design and implement new organizational models, embed AI across key workflows, drive enterprise-wide transformation programs, improve operating effectiveness, and ensure successful adoption of change. By combining strategy, AI engineering, organizational design, change management, and program execution, the team helps align people, processes, and priorities to support long-term growth and business performance. The Process Redesign Lead is accountable for defining the operating model and process architecture: leading process discovery, mapping current-state journeys, and architecting redesigned processes through to implementation handoff. The Director-level Process Redesign Lead brings deep process expertise, AI fluency, and structural-frame thinking to the most ambiguous, cross-functional problem spaces, translating strategic intent into clean, scalable operating designs. The ideal candidate is highly motivated, intellectually curious, analytical, and possesses an entrepreneurial mindset, with a track record of modernizing legacy

AIProject ManagementRecruitment
G
📍 California, Foster City, United States
✓ Quality checkedCompany trend -1.6%

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description As part of Gilead’s enterprise AI strategy to accelerate insights and decision‑making, we are seeking an Sr Manager, Data/AI Solution Architect to lead the design of Data and AI solutions across the HR & LCCR Functions. In this role, you will partner closely with business stakeholders, and Data/AI Product Owners, Technical Delivery Leads and Platform Leads to determine the right solution architecture for predictive analytics and AI‑driven insights. You will drive technical excellence through architectural design, modeling approach, and platform selection—ensuring scalable solutions, aligned to Gilead standards, that translate complex digital needs into actionable insights.</

PythonAWSAIRecruitment
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📍 United States· Remote
✓ Quality checkedCompany trend -90.5%

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Why this role is on the menu Instacart’s product and technology partnerships — spanning logistics, retail technology, and enterprise products — are a core lever for how we build and grow. But as our ambitions scale into new product areas and international markets, the function needs more than experienced deal-makers. It needs a senior leader who can set the multi-year vision, personally own the most consequential relationships, and shape how Instacart decides what to build versus buy versus partner. Without this person, we risk reactive partnership decisions, misalignment between partnerships and product strategy, and missed first-mover opportunities in markets where speed matters. We’re hiring a Director of Product Partnerships to lead the team and function at the highest level — influencing build-buy-partner tradeoffs with senior leadership, taking first-of-a-kin

S
📍 Aliso Viejo, United States· Remote
✓ High-confidence listing

$193.4K – $276.3K/yr

Quick readStrong listing-quality and freshness signals

Real people. Real service. At SupplyHouse.com , we value every individual team member and cultivate a community where people come first. Led by our core values of G enerosity, R espect, I nnovation, T eamwork, and GRIT, we’re dedicated to maintaining a supportive work environment that celebrates diversity and empowers everyone to reach their full potential. As an industry-leading e-commerce company specializing in HVAC, plumbing, heating, and electrical supplies since 2004, we strive to foster growth while providing the best possible experience for our customers. We are looking for a Director of Product to own our product operating model end to end: the practice of product management, the delivery engine that gets work shipped, and the annual roadmap that connects both to company strategy. Reporting into our COO, this individual will lead a team of Product Managers embedded in cross-functional pods and hold those pods accountable for measurable customer and business outcomes. The Director of Product will work in close partnership with the VP of IT, Senior Manager of UX, Director of Enterprise AI Adoption, and business leaders to connect customer needs, business priorities, technical strategy, and execution. If you’re passionate about building high-performing product organizations, enjoy turning strategy into action, and are excited to lead cross-functional teams in delivering product experiences that are strategically sound, technically feasible, thoughtfully designed, and impactful for customers and the business, we want to hear from you! This remote position is open to individuals who live in, or are open to relocating to, the following states: Arizona, Delaware, Florida, Georgia, Kentucky, Nevada, New Jersey, New York, North Carolina, Ohio, Rhode Island, South Carolina, Tennessee, Texas, Virginia, and Washington. This position requires travel to our headquarters in Melville, NY 6 times per year for internal meetings and team building activities.

AIProject ManagementCustomer Service
RH
📍 New York, New York, United States· Full-time
✓ High-confidence listing

$150.9K – $190K/yr

Quick readStrong listing-quality and freshness signals

Healthcare is complex. We’re here to change that. RVO Health is a health technology company on a mission to make health easier to navigate, more accessible, and more affordable for everyone. Here, you'll help over 40 million people every month, with a team that genuinely cares about the work and each other. AT A GLANCE RVO Health is seeking an experienced and highly analytical Director, SEO & AEO to own organic search performance across our entire suite of health brands, including Healthline (The #1 health website in Google AI Overviews and ChatGPT visibility), Healthgrades (The #1 healthcare finder website), Medical News Today, and more. This role leads and scales a high-performing SEO team, setting strategy and driving measurable growth in both team capability and organic traffic. The Director brings deep and varied SEO expertise, spanning traditional Google search, Agentic search (AEO), and Social search, and translates that expertise into performance gains and business impact across our digital ecosystem. This is a highly visible leadership role with direct collaboration at the VP+ level, requiring strong analytical rigor, technical depth, and the ability to connect SEO performance to enterprise priorities. Where You'll Be Location: New York City, NY | Hybrid We believe great collaboration happens when we're together, solving problems, learning from each other, and connecting as a team. That's why we’re in our offices Tuesday through Thursday each week. You are welcome to work remotely Mondays and Fridays if you wish. Office address: 250 Park Ave S, New York, NY 10003 (Union Square) What You’ll Do Lead, coach and scale a highly performant SEO team across multiple priorities and brands. Develop team-wide SEO (Google, Agentic, Social) strategies, across every stage of the health search journey (including for Healthline and Healthgrades), based on a nuanced understanding of site performance, SEO data, Google's updates, and third-party industry insights, in alig

GitAIGoRust
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📍 Boston, Massachusetts, United States· Full-time
✓ High-confidence listing

From $159.9K/yr

Quick readStrong listing-quality and freshness signals

We take play seriously. We’re looking for curious adventurers ready to find their party, fueled by imagination and drive to build what’s never been built before. At Hasbro and Wizards of the Coast, you’ll collaborate with passionate teams to reimagine our iconic brands and create experiences that spark joy, connection, and community through the magic of play. This is your chance to shape legendary play that lasts a lifetime. At Hasbro, our mission is to entertain and connect generations of fans through the wonder of storytelling and exhilaration of play. We're looking for adventurous and curious people who want to explore, experiment, and innovate to come up with the best ideas. Our culture has inspired our diverse team of highly skilled, highly creative, and highly committed individuals for 100 years and we believe the best is yet to come. We're hiring a Senior Principal, Technical Product Manager to help turn that vision into reality. This is a highly influential, hands-on individual contributor role with global scope. You'll identify process complexity, design practical automation solutions, and lead AI experimentation that delivers measurable impact for our Marketing, Brand, and Commercial teams worldwide. You'll work at the intersection of business and technology - partnering closely with cross-functional leaders to translate real workflow challenges into scalable, sustainable improvements. Success in this role means simplifying planning and execution processes, reducing manual effort, growing transparency, and introducing AI-enabled capabilities that build tangible business value. If you're motivated by solving meaningful enterprise problems and building practical solutions that make teams more effective, this is an opportunity to build how Hasbro works. What You'll Drive: Process Simplification & Workflow Design Assess end-to-end workflows across Marketing, Brand, and Commercial teams to identify friction, excess, and opportunity. Redesign

AIGoMarketingFinance
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📍 Seattle, Washington, United States· Full-time
✓ High-confidence listing

$280K – $350K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Product at Brex The Product team is at the forefront of Brex's mission to empower employees anywhere to make better financial decisions. With a deep understanding of the business, we identify and scope the most impactful opportunities for Brex to tackle. We align cross-functional teams—including Engineering, Legal, Compliance, and Design—on key decisions, set strategy, and drive products from inception to launch. What you’ll do Embedded is one of Brex’s fastest-growing enterprise channels, bringing our card program into the financial software and workflows customers already trust. As Staff Product Manager, you will lead its next phase. What began as a project is now a line of business. You will build the Embedded API and partner platform to unlock 10x growth, accelerate partner launches, and expand the financial capabilities available across the ecosystem. This is a broad, commercially accountable Staff IC role across Product, Card In

AIRustAccountingFinance
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📍 San Francisco, California, United States· Full-time
✓ High-confidence listing

$280K – $350K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Product at Brex The Product team is at the forefront of Brex's mission to empower employees anywhere to make better financial decisions. With a deep understanding of the business, we identify and scope the most impactful opportunities for Brex to tackle. We align cross-functional teams—including Engineering, Legal, Compliance, and Design—on key decisions, set strategy, and drive products from inception to launch. What you’ll do Embedded is one of Brex’s fastest-growing enterprise channels, bringing our card program into the financial software and workflows customers already trust. As Staff Product Manager, you will lead its next phase. What began as a project is now a line of business. You will build the Embedded API and partner platform to unlock 10x growth, accelerate partner launches, and expand the financial capabilities available across the ecosystem. This is a broad, commercially accountable Staff IC role across Product, Card In

AIRustAccountingFinance
B
📍 New York, New York, United States· Full-time
✓ High-confidence listing

$280K – $350K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Product at Brex The Product team is at the forefront of Brex's mission to empower employees anywhere to make better financial decisions. With a deep understanding of the business, we identify and scope the most impactful opportunities for Brex to tackle. We align cross-functional teams—including Engineering, Legal, Compliance, and Design—on key decisions, set strategy, and drive products from inception to launch. What you’ll do Embedded is one of Brex’s fastest-growing enterprise channels, bringing our card program into the financial software and workflows customers already trust. As Staff Product Manager, you will lead its next phase. What began as a project is now a line of business. You will build the Embedded API and partner platform to unlock 10x growth, accelerate partner launches, and expand the financial capabilities available across the ecosystem. This is a broad, commercially accountable Staff IC role across Product, Card In

AIRustAccountingFinance
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