Jobs in United States

Lead Senior Manager Application Security in United States

2,434 active opportunities · Updated October 2026

Explore current lead senior manager application security jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$195.7K – $253.2K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description As an Associate Director, Global Commercial Project Management at Gilead you will report to the Senior Director, Global Commercial Project Management and will serve as the project manager of early Commercialization and Commercialization Teams (eCTs / CTs). This role will lead strategic execution and support governance while coordinating cross-functional teams and initiatives to ensure successful delivery and operational execution of their teams’ priorities. This role will primarily support Gilead’s programs in Liver and Inflammation with the opportunity to support other therapeutic areas as needed. The successful candidate will be dynamic, with excellent project management capabi

AIProject ManagementPmpRecruitment
L
📍 New York, NY, United States
✓ High-confidence listingCompany trend +33.3%
Quick readStrong listing-quality and freshness signals

At Lyft, our purpose is to serve and connect. We aim to achieve this by cultivating a work environment where all team members belong and have the opportunity to thrive. Safety is fundamental to the Lyft experience and to the trust riders, drivers, and our broader communities place in our platform. Lyft’s Safety and Customer Care team works through product, technology, data, policy, and operations to prevent harm before it happens, respond compassionately when it does, and continuously learn from every incident in efforts to make Lyft the safest way to get around. We are looking for an experienced safety leader with deep Trust & Safety experience to help turn Lyft’s Trust & Safety strategy into impact at scale, with the final shape of this role informed by the strengths of the leader we bring on. This is a highly visible leadership role within Lyft’s Safety & Customer Care organization. You will report to the Senior Director and General Manager of Trust & Safety and sit on the Trust & Safety leadership team. You will additionally partner deeply with Product, Engineering, Data Science, Research & Design, Legal, Compliance, Risk, Communications, Finance, and other teams across Lyft. The ideal candidate is an exceptional operator and people leader with Trust & Safety expertise, strong strategic judgment, and a track record of leading complex, high-stakes Trust & Safety organizations at scale. You can move fluidly between setting strategy with senior executives, developing leaders, overseeing large global operations and budgets, and diving into an emerging safety issue when the situation demands it. Responsibilities Lead Global Safety Compliance & Risk Oversee Lyft’s global safety compliance, transparency, and risk functions, supporting strong functional leaders and individual contributors on your team and strengthening capabilities as Lyft scales globally. Set direction across compliance readiness, safety transparency repo

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📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -100%
Quick readStrong listing-quality and freshness signals

GitLab is the intelligent orchestration platform for DevSecOps. GitLab enables organizations to increase developer productivity, improve operational efficiency, reduce security and compliance risk, and accelerate digital transformation. More than 50 million registered users and more than 50% of the Fortune 100* trust GitLab to ship better, more secure software faster. The same principles built into our products are reflected in how our team works: we embrace AI as a core productivity multiplier, with all team members expected to incorporate AI into their daily workflows to drive efficiency, innovation, and impact. GitLab is where careers accelerate, innovation flourishes, and every voice is valued. Our high-performance culture is driven by our values and continuous knowledge exchange, enabling our team members to reach their full potential while collaborating with industry leaders to solve complex problems. Co-create the future with us as we build technology that transforms how the world develops software. * Fortune 500® is a registered trademark of Fortune Media IP Limited, used under license. Claim based on GitLab data. Fortune 100 refers to the top 20% ranked companies in the 2025 Fortune 500 list, published in June 2025. Fortune and Fortune Media IP Limited are not affiliated with, and do not endorse products or services of GitLab. An overview of this role Join us at a pivotal moment as we scale our revenue operations globally. As Chief of Staff to the CRO, you'll serve as a strategic partner and force multiplier to our revenue leadership team, driving operational excellence and orchestrating high-impact initiatives. As part of the Office of the CRO, you'll also manage our Communications lead and CRO Initiatives Program Manager, giving you direct ownership over how the CRO's key initiatives get built and run. This highly visible role offers a unique opportunity to shape strategy at the executive level while developing your path to senior leadership. Y

GitRestAIGo
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📍 New York, New York, United States· Full-time
✓ Quality checkedCompany trend -72.3%

We believe that the way people interact with their finances will drastically improve in the next few years. We’re dedicated to empowering this transformation by building the tools and experiences that thousands of developers use to create their own products. Plaid powers the tools millions of people rely on to live a healthier financial life. We work with thousands of companies like Venmo, SoFi, several of the Fortune 500, and many of the largest banks to make it easy for people to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Washington D.C., London and Amsterdam. Security Engineering is the engineering function inside the Plaid security org that focuses on developing the industry-leading security systems and infrastructure. Security Engineering owns most of Plaid’s security-related infrastructure: secure data storage, key management systems, internal identity platform, internal authentication systems, internal permission management, and internal authorization service. We develop solutions across data encryption, key management, access control, and data loss prevention to protect sensitive consumer data. We believe in the Zero Trust security model and are always looking for ways to improve our authentication and access control platforms. About the role: You will develop security capabilities to secure Plaid infrastructure and sensitive data access. You will lead the team’s strategic planning in collaboration with the manager and other senior engineers. You will own, maintain, and build Plaid’s security infrastructure and services like IAM Gateway, Key Management System and Network Firewall. You will consult with product engineers to ensure Plaid services meet security standards. You will help educate and support other engineering teams to improve security in

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📍 United States· Full-time
✓ Quality checkedCompany trend -94.3%

Who we are About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies - from the world’s largest enterprises to the most ambitious startups - use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone's reach while doing the most important work of your career. About the team Stripe's mission is to increase the GDP of the internet — and we do that responsibly. The User Risk Strategy (URS) function is at the heart of that responsibility: it is the team that defines who Stripe can do business with , on what terms, and how those standards are maintained and enforced at scale. The function sits within the First Line of Defense in Stripe's Risk organization and is the authoritative owner of Stripe's supportability framework. We are looking for a seasoned leader to own and evolve the URS / Supportability function as a Manager of Managers (M2). In this role, you will lead a team of risk strategists and analysts across Ecosystem Strategy, New Product Enablement, User Insights & Enablement, Platform Risk Strategy, and Enforcement & Monitoring Strategy (EMS). You will be a senior leader in the Risk Strategy organization, shaping the direction of Stripe's supportability ecosystem and driving cross-functional decisions that directly influence Stripe's ability to grow safely. In this role, you will report into the Head of Risk Strategy and partner closely with Product, Engineering, Legal, Financial Crimes, Financial Partnerships, Operations, and GTM leadership. What you’ll do Responsibilities Strategy & Vision Own the long-term vision and strategy for Stripe's User Risk / Supportability function, ensuring legitimate users can use Stripe while protecting Stripe's financial platform, brand, and regulatory s

GitRestAIGo
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📍 Menlo Park, California, United States· Full-time
✓ Quality checkedCompany trend -92.9%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. The Position Snowflake is seeking a Sr. Director, GTM Process & Operations to own our global GTM operating model, reporting to the SVP of Revenue Strategy and Operations. This executive role defines how Snowflake's revenue motion runs — setting business priorities and processes, leading AI and automation adoption across GTM workflows, and standardizing the Quote-to-Cash and field support functions that directly drive revenue velocity. You will own the operating cadence that connects GTM strategy to execution, lead cross-functional alignment across Sales, Finance, Legal, and Partner Operations, and manage a global team of Directors, Senior Managers, and specialists across QTC, Core Sales, and Shared Services. As a key leader in Snowflake's AI-native RevOps evolution, you will inherit a highly capable team and push it further — ensuring Snowflake's own revenue operations are the best proof point for Snowflake's technology. Key Responsibilities GTM Business Strategy & Operating Model Own GTM business priorities, processes, policies, and operating metrics across the revenue motion. Define field requirements and translate GTM strategy into clear business cases and outcome targets. Drive the operating cadence that connects strategy to execution. AI & Automation Adopti

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📍 New York, New York, United States· Full-time· Remote
✓ High-confidence listingCompany trend -72.3%
Quick readStrong listing-quality and freshness signals

We believe that the way people interact with their finances will drastically improve in the next few years. We’re dedicated to empowering this transformation by building the tools and experiences that thousands of developers use to create their own products. Plaid powers the tools millions of people rely on to live a healthier financial life. We work with thousands of companies like Venmo, SoFi, several of the Fortune 500, and many of the largest banks to make it easy for people to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Seattle, Washington D.C., Raleigh, London, and Amsterdam. At Plaid, our mission is to empower innovators by delivering access to the financial system. Since 2012 we've helped tens of millions of consumers live a better financial life and thousands of customers build a new financial future. We work with companies like PayPal, Rocket, H&R Block, and many of the largest banks in the US to make it easy for consumers to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Seattle, Raleigh, Washington D.C., London and Amsterdam. The Account Management team in Plaid’s Enterprise Segment leverages deep product and industry expertise to help our customers build and scale technology solutions. We act as partners, advisors, and advocates for our customers to help shape how consumers interact with their finances. As an Enterprise Account Management Lead, you’ll be responsible for managing the team of senior account managers who are growing the revenue from the Enterprise customer base, as well as setting the vision and strategy to build long-term

AWSAIGoFinance
C
📍 Tampa Florida United States, United States
✓ High-confidence listingCompany trend +800%
Quick readStrong listing-quality and freshness signals

This is a senior attorney role to lead the negotiation and execution of derivatives documentation supporting our global Markets trading activities. This role will serve as a key partner to front office, risk, and legal teams, managing complex master trading agreements, such as ISDA and Futures Clearing agreements, and advising on legal and regulatory risk across OTC derivatives transactions. The position requires deep expertise in ISDA Master Agreements, collateral documentation, and derivatives market practice, along with strong stakeholder management and negotiation capabilities. Responsibilities: Serve as lead negotiator and subject matter expert for ISDA Master Agreements, Schedules, Credit Support Annexes (CSAs), and related derivatives and collateral documentation; manage complex, bespoke negotiations across the full documentation lifecycle Provide legal counsel and guidance to Markets business stakeholders, interpreting applicable laws, rules, regulations, and industry practices and delivering commercially practical, risk-appropriate solutions Advise senior management on legal matters impacting trading activities, client relationships, and strategic initiatives, contributing informed, business-oriented perspectives to decision-making Identify, evaluate, and manage legal, regulatory, and reputational risk in coordination with Legal, Risk, and ICRM; ensure alignment with internal policies and applicable regulatory requirements Objectively assess business proposals against institutional risk appetite, regulatory frameworks, and market standards, escalating issues as appropriate Collaborate closely with Trading, Sales, Credit, Risk, Operations, and Legal teams across regions to deliver coordinated, efficient, and consistent outcomes Oversee day-to-day legal and documentation activities as a subject matter expert, ensuring tim

Artificial IntelligenceAI
H
📍 Louisville, United States
✓ High-confidence listingCompany trend +310%
Quick readStrong listing-quality and freshness signals

Become a part of our caring community The Senior Portfolio Enablement Lead is a strategic portfolio transformation role responsible for shaping and enabling Humana's portfolio operations, Agile Release Train (ART) design, and Ways of Working across the portfolio. Acting as a trusted advisor to senior executives (SVPs, VPs, and portfolio leaders), the role translates transformation strategy into scalable execution by diagnosing portfolio delivery challenges, guiding organizational design, and improving alignment, flow, and value delivery. As a Senior Portfolio Enablement Lead, you will: Partner with portfolio and organization leadership to develop and enable portfolio, aligned to enterprise portfolio operations to achieve portfolio initiatives their outcomes. Perform quantitative and qualitative assessments, including stakeholder analysis and change impact assessments, to develop data-driven change strategies for key stakeholder groups. Build and manage portfolio transformation roadmaps to drive executive buy-in and sponsor engagement across technology and business/product leadership and leadership to drive understanding and adoption of key changes Develop Release Train Engineers to our Humana Ways of Working and enterprise tooling subject matter experts for Agile Release Trains and Scrum Teams Measure effectiveness of change interventions through defined metrics and continuously evolve plans to optimize adoption outcomes Regularly report activity status to organizational, portfolio and transformation leadership; proactively escalate and help resolve risks and issues Partners with leaders to align all continuous improvement goals and objectives Partner with Release Train Engineers in the portfolio to monitor activity level of continuous improvement, adoption of Humana Ways of Working, risks patterns

AzureAIRecruitment
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📍 San Francisco, United States· Full-time
✓ High-confidence listingCompany trend -98.8%

From $156K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. About Airbnb Host Community Airbnb creates opportunities for millions of hosts to build a business, develop connections with guests and hosts, and positively impact local communities. The strength of the global Host community sets Airbnb apart. We keep hosts at the center of everything we do. The Airbnb Community team treats hosts as partners by fostering connection, supporting their development and success, and incorporating their feedback in our product and policies. About the Role The Senior Host Development Lead is an experienced leader responsible for the creation and execution of global educational programs and systems that inspire and empower Airbnb hosts to grow their business and deliver high quality hospitality. This role collaborates cross-functionally to build strategy, define scope, and lead execution of initiatives that support host onboarding, continuous learning, and long-term development throughout the host journey. Aligned with Airbnb’s highest-priority company goals, these initiatives take the form of scalable solutions—such as in-product content, webinars, workshops, articles, and online toolkits—designed to meet diverse learning styles and contexts in a way that is globally consistent and locally relevant. Each educational touchpoint is conceived as part of a broader, holistic system that shapes host success through education and recognition. Responsibilities: Drive the vision and strategy of key host education programs across the host lifecycle, from onboarding to long-term optimization. Manage the end-to-end strategy, design, and execution of scaled host education initiatives

AIGoExcelMarketing
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📍 New York, United States· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

ROLE SUMMARY We are looking for a Senior Data Scientist to lead complex data science engagements that combine traditional statistical modelling with Generative AI. You will work hands-on with very large datasets across disparate systems and formats, translate ambiguous business problems into rigorous analytical solutions, and present those solutions clearly to C-level stakeholders. This is a delivery-first role with a fast track into technical leadership: alongside your own project work, you will help guide junior data scientists and shape how Lynx builds and ships data science solutions. KEY RESPONSIBILITIES Solution Design & Delivery Design and deliver end-to-end solutions for defined data science problems, combining classical modelling, data transformation, and Generative AI / LLM techniques. Work hands-on with very large datasets across disparate stores and formats, from ingestion and transformation through to modelling and validation. Apply statistical and machine learning methods to business problems such as customer retention, campaign management, and commercial performance optimisation. Client Communication & Leadership Present results and prepare client-ready materials for project stakeholders, including C-level audiences, translating technical work into clear business narratives. Lead smaller data science workstreams, with support from internal leadership and the PMO, including day-to-day guidance for junior team members. Partner with delivery and account teams to scope problems, set realistic timelines, and manage stakeholder expectations. Knowledge Building Create reusable documentation, presentations, and code libraries during projects so future engagements can build on prior work. Participate in internal education, research, and knowledge-sharing initiatives that raise the technical bar across the practice. SKILLS, QUALIFICATIONS AND EXPERIENCE 8+ years of overall experience in data science, with a track record of leading analytic

PythonSQLAWSAzure
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📍 Texas, California, United States· Full-time
✓ Quality checkedCompany trend -100%

Coder is looking for a Senior Sales Development Representative (SDR) to fuel our growth by generating qualified pipeline for our Enterprise Account Managers. You’ll help bring Coder’s Environment-as-a-Service platform to some of the world’s largest companies that are adopting AI-driven development at scale. This role is all about creating opportunities: finding and engaging the right prospects, uncovering the pain points Coder can help with, and setting up qualification calls that set our EAMs up for success. You’ll play a critical role in driving Coder’s outbound motion and helping large organizations build software faster, more securely, and at scale through the collaboration of AI coding agents and human developers. In the US, this is a hybrid position and requires in-office presence three days a week at our office in South Austin (78704). What you’ll do here Generate qualified opportunities for EAMs through targeted outbound prospecting Conduct multi-channel outreach across phone, email, and LinkedIn using tools like SalesLoft, Sales Navigator, ZoomInfo, 6sense, and Nooks Research target accounts and key personas to craft personalized and value-driven messaging Set up qualification calls for EAMs to run and advance through the sales cycle Work closely with EAMs to strategize account outreach and hand off qualified opportunities seamlessly Maintain accurate activity and lead data in CRM and engagement platforms Collaborate with marketing to align messaging and campaigns to drive higher response rates Stay sharp on developer tooling, platform engineering, and AI-driven development trends to speak credibly with prospects What we’re looking for 1-3 years in outbound SDR or BDR roles within SaaS or developer-focused technology companies Proven ability to generate pipeline through outbound cold calling, emailing, and social selling Experience with SalesLoft, LinkedIn Sales Navigator, ZoomInfo, 6sense, and similar prospecting tools Strong written and verbal communicati

AWSAIGoDevOps
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📍 Bellevue, WA, United States· Full-time
✓ High-confidence listingCompany trend -91.7%
Quick readStrong listing-quality and freshness signals

For over 20 years, Smartsheet has empowered teams to manage work seamlessly and scale solutions smarter. Now, in our most ambitious chapter yet, we are uniting human teams with AI agents. By orchestrating the work agents do best, automating manual tasks and uncovering insights at scale, we create the space for people to focus on what truly matters: judgment, creativity, and big thinking. That is magic at work, and it’s what we show up for every day. Corporate Systems Engineering builds and operates the software platforms, integrations, and automations that power Smartsheet’s core business functions across Finance, Sales/GTM, and People & Culture. Our team owns mission-critical systems and workflows that enable how the company hires, sells, bills, pays, reports, and scales. We operate at the intersection of software engineering, enterprise platforms, and business-critical data, treating internal systems with the same rigor, reliability, and product mindset as customer-facing software. The Automation team builds human-to-system and system-to-system automations that reduce manual effort and friction across the business. We combine cloud-native services, agentic AI, and workflow orchestration to enable employees to interact with enterprise systems through intelligent, secure, and auditable automation. As a Senior Software Engineer I (Automation), you will lead the design, build, and operation of systems and workflows that directly support business execution at scale. You will own complex technical initiatives, partner with Product Managers and stakeholders on technical roadmaps, and mentor junior engineers. This full-time position reports to the Sr. Director, Development and can be located in our Bellevue, WA office, or you may work remotely from anywhere in the US where Smartsheet is a registered employer. You Will: Architect AI Agents: Take a leading role in designing Agentic Workflows using AWS Step Functions and Bedrock Agents that reason

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C
📍 Hartford, United States
✓ High-confidence listingCompany trend +340.2%
Quick readStrong listing-quality and freshness signals

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Position Summary The Director of the Divestiture Management Office (DMO) will lead the team responsible for delivering on a Transition Services Agreements (TSAs) following the sale of a CVS Health business unit. This role serves as the primary liaison between CVS Health, the acquiring company, vendors, and impacted employees to ensure all transition commitments are successfully executed. The ideal candidate is a strong leader who can manage complex programs, build relationships across multiple stakeholders, and drive solutions in a fast-paced environment. Key Responsibilities Lead and manage the Divestiture Management Office and supporting team members. Oversee execution of Transition Services Agreement (TSA) commitments and contractual obligations. Build and maintain relationships with buyers, vendors, impacted employees, and CVS stakeholders. Review and interpret legal agreements, contracts, and transaction documents. Identify risks, issues, and improvement opportunities, and drive resolution through collaboration and negotiation. Provide clear updates, recommendations, and reporting to senior leadership. Manage project budgets and ensure financial goals are met. Track program performance through metrics, reporting, and governance processes. Lead project planning, execution, and continuous improvement efforts.

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📍 Remote, United States· Remote
✓ High-confidence listingCompany trend -8%
Quick readStrong listing-quality and freshness signals

NVIDIA’s DGX Cloud organization is seeking a Senior Data Engineer to become part of its data team! We develop the reliable data foundation that supports fleet health, capacity, utilization, cost, reliability, and operational decision-making throughout DGX Cloud. Our platform supports engineering, operations, finance, and product teams managing and expanding large GPU fleets across cloud service providers and NVIDIA Cloud Partners. We are looking for a practical engineer and technical lead to take charge of a key part of the Navigator data platform. We develop the systems that transform distributed infrastructure telemetry and operational data into dependable, managed data products that support fleet health, capacity, utilization, cost, and operational decisions. We are seeking a hands-on, platform-minded engineer to build and evolve the systems that turn distributed infrastructure telemetry and operational data into reliable, governed data products. You will work across ingestion, transformation, data quality, platform architecture, security, observability, and self-service consumption to help make Navigator and the DGXC data platform a dependable source of truth. We do expect strong engineering fundamentals, experience operating production systems, and the ability to learn new platforms and domains quickly. What you'll be doing: Own systems end to end. For example, work from ambiguous customer and operational needs through architecture, implementation, deployment, observability, incident response, and ongoing support. Construct data pipelines and products. Such as designing and maintain batch and streaming ingestion, transformation, reconciliation, and serving paths for fleet, capacity, utilization, cost, scheduling, and operational telemetry. Build shared libraries, workflow and DAG or equivalent experience abstractions to evolve the data platform. Develop deployment tooling, data

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