Jobs in United States

Lead Senior Python Engineer in United States

2,434 active opportunities · Updated October 2026

Explore current lead senior python engineer jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

C
📍 Jersey City New Jersey United States, United States
✓ High-confidence listingCompany trend +800%
Quick readStrong listing-quality and freshness signals

Join a pioneering team at the forefront of financial technology innovation. We are building a cutting-edge, agentic AI platform designed to revolutionize the end-to-end credit risk model development lifecycle. By leveraging the power of Large Language Models (LLMs) and intelligent workflows, we aim to augment our quantitative modelers, dramatically increasing their productivity, enhancing model governance, and accelerating the delivery of critical risk models. We are seeking a senior, hands-on technology leader to drive this transformation. In this role, you will partner directly with quantitative analysts and key stakeholders to shape the most impactful use cases and then lead a team of talented developers to design, build, and deploy the generative AI platform that brings this vision to life. Key Responsibilities Strategic Vision & Stakeholder Partnership: Collaborate closely with quantitative model developers, Model Risk Management (MRM), and business leaders to deeply understand their pain points and translate them into a technical vision and product roadmap. Identify, scope, and prioritize use cases for the agentic workflow platform, ensuring they deliver measurable value and align with strategic objectives. Serve as the primary technical liaison between the engineering team and its users, ensuring a tight feedback loop and continuous alignment. Platform Design & Hands-On Development: Lead the architectural design of a scalable, robust, and secure agentic AI platform, including core components for orchestration, knowledge retrieval (e.g. RAG), and tool integration. Engage in hands-on software development to build foundational components, create proofs-of-concept, and tackle the most complex technical challenges. Design and implement secure integrations with internal data sources, external APIs, and various LLMs, ensuring compliance

PythonJavaArtificial IntelligenceAI
O
📍 Atlanta, Georgia, United States
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

Strength in Trust OneTrust’s mission is to enable innovation through the responsible use of data and AI. We believe that ensuring data is trusted shouldn’t slow teams down—it should accelerate what’s possible. This led us to develop the first technology platform for responsible data use in 2016. Today, with AI representing the latest and most impactful expansion of data yet, OneTrust is once again redefining what responsible innovation looks like. OneTrust, the AI‑Ready Governance Platform™, unifies regulatory intelligence, automation, and connected governance workflows so businesses can continue to move at the speed of AI while ensuring good governance to prevent data misuse at scale. Trusted by thousands of organizations worldwide, OneTrust is shaping the future where trusted data becomes a transformative force for business and society. The Challenge As a Senior Staff Software Engineer, you will serve as a technical leader for OneTrust’s AI Governance (AIG) platform, driving the design, scalability, and reliability of systems that enable enterprises to deploy and govern AI and LLM-powered applications responsibly. You will deeply understand how customers build, deploy, and operate AI systems, and translate those needs into secure, compliant, and observable platform capabilities. Your Mission Development Lead the design and development of Java/Python microservices and shared libraries integrating with AI platforms for OneTrust’s AI Governance product. Design, build, and test cloud-native applications deployed on Microsoft Azure using Core Java, REST, and the Spring ecosystem. Lead the architecture and development of reusable AIG reporting and dashboard capabilities that integrate governance data from SQL databases and analytical platforms with runtime observability signals. Design reusable semantic-layer and metric-abstraction capabilities, including dataset contracts, metric defini

PythonJavaSQLAWS
O
📍 San Francisco, California, United States
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

Strength in Trust OneTrust’s mission is to enable innovation through the responsible use of data and AI. We believe that ensuring data is trusted shouldn’t slow teams down—it should accelerate what’s possible. This led us to develop the first technology platform for responsible data use in 2016. Today, with AI representing the latest and most impactful expansion of data yet, OneTrust is once again redefining what responsible innovation looks like. OneTrust, the AI‑Ready Governance Platform™, unifies regulatory intelligence, automation, and connected governance workflows so businesses can continue to move at the speed of AI while ensuring good governance to prevent data misuse at scale. Trusted by thousands of organizations worldwide, OneTrust is shaping the future where trusted data becomes a transformative force for business and society. The Challenge As a Senior Staff Software Engineer, you will serve as a technical leader for OneTrust’s AI Governance (AIG) platform, driving the design, scalability, and reliability of systems that enable enterprises to deploy and govern AI and LLM-powered applications responsibly. You will deeply understand how customers build, deploy, and operate AI systems, and translate those needs into secure, compliant, and observable platform capabilities. Your Mission Development Lead the design and development of Java/Python microservices and shared libraries integrating with AI platforms for OneTrust’s AI Governance product. Design, build, and test cloud-native applications deployed on Microsoft Azure using Core Java, REST, and the Spring ecosystem. Lead the architecture and development of reusable AIG reporting and dashboard capabilities that integrate governance data from SQL databases and analytical platforms with runtime observability signals. Design reusable semantic-layer and metric-abstraction capabilities, including dataset contracts, metric defini

PythonJavaSQLAWS
PG
📍 Aliso Viejo, United States· Remote
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

Why Sony Interactive Entertainment? Sony Interactive Entertainment isn’t just the Best Place to Play — it’s also the Best Place to Work. Sony Interactive Entertainment (SIE) is the company behind the PlayStation brand. As a subsidiary of Sony Group Corporation, we’re part of a proud legacy of innovation and excellence. SIE is a dynamic technology company, delivering cutting-edge hardware and network services to more than 100 million people and an entertainment leader, home to some of the most beloved and recognizable intellectual properties (IP) in the world. Our role at SIE is to create and nurture the experiences under the PlayStation brand, a name synonymous with entertainment excellence and creativity. Reporting to the Director of Global Vulnerability Management, you will serve as a Senior Security Research Engineer and technical lead within SIE’s Global Vulnerability Management team. You will lead complex work that advances our Threat Exposure Management capability and supports our transition to a Continuous Threat Exposure Management operating model, while remaining directly engaged in vulnerability research, analysis, security validation, prioritization, and remediation support. You will partner across Information Security, engineering, technology, and business teams to improve how SIE discovers, prioritizes, validates, and mobilizes action on security risks. You will translate annual TEM goals into defined workstreams, delivery plans, success measures, and repeatable operating practices that improve visibility, decision-making, remediation outcomes, and program scale. Responsibilities Lead complex Global Vulnerability Management workstreams that advance SIE’s Threat Exposure Management capability and transition toward a Continuous Threat Exposure Management operating model across discovery, prioritization, validation, and mobilization. Translate annual TEM goals into defined delivery plans, milestones, success measures, dependencies, and repeatable operating

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C
📍 Work From Hom, United States
✓ High-confidence listingCompany trend +340.2%
Quick readStrong listing-quality and freshness signals

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. POSITION SUMMARY CVS Health is seeking a Senior Full Stack Engineer, Agentic AI Platform to join and lead engineering efforts for Lumina, CVS Health's enterprise knowledge and agentic AI platform. The Senior Full Stack Engineer, Agentic AI Platform will provide both technical and people leadership while driving the evolution of a platform that delivers trusted, secure, and governed AI experiences across the enterprise. As a Senior Full Stack Engineer, Agentic AI Platform, you will own the technical direction, architecture, scalability, and operational excellence of Lumina while leading a team of engineers and data scientists responsible for building and supporting the platform. This is a hands-on leadership role requiring active contribution to production code, architectural decision-making, code reviews, and engineering best practices, while simultaneously coaching and developing team members. The Senior Full Stack Engineer, Agentic AI Platform will play a critical role in advancing agentic AI capabilities, retrieval-augmented generation (RAG) systems, Model Context Protocol (MCP) integrations, enterprise search, knowledge ingestion, and AI governance. You will drive platform enhancements that improve retrieval quality, strengthen security and access controls, expand automation capabilities, and ensure the platform remains reliable, observable, and scalable as adoption accelerates across CVS

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📍 Remote, United States· Remote
✓ High-confidence listingCompany trend -8%
Quick readStrong listing-quality and freshness signals

NVIDIA’s DGX Cloud organization is seeking a Senior Data Engineer to become part of its data team! We develop the reliable data foundation that supports fleet health, capacity, utilization, cost, reliability, and operational decision-making throughout DGX Cloud. Our platform supports engineering, operations, finance, and product teams managing and expanding large GPU fleets across cloud service providers and NVIDIA Cloud Partners. We are looking for a practical engineer and technical lead to take charge of a key part of the Navigator data platform. We develop the systems that transform distributed infrastructure telemetry and operational data into dependable, managed data products that support fleet health, capacity, utilization, cost, and operational decisions. We are seeking a hands-on, platform-minded engineer to build and evolve the systems that turn distributed infrastructure telemetry and operational data into reliable, governed data products. You will work across ingestion, transformation, data quality, platform architecture, security, observability, and self-service consumption to help make Navigator and the DGXC data platform a dependable source of truth. We do expect strong engineering fundamentals, experience operating production systems, and the ability to learn new platforms and domains quickly. What you'll be doing: Own systems end to end. For example, work from ambiguous customer and operational needs through architecture, implementation, deployment, observability, incident response, and ongoing support. Construct data pipelines and products. Such as designing and maintain batch and streaming ingestion, transformation, reconciliation, and serving paths for fleet, capacity, utilization, cost, scheduling, and operational telemetry. Build shared libraries, workflow and DAG or equivalent experience abstractions to evolve the data platform. Develop deployment tooling, data

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📍 Austin, Texas, United States· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

About us Graphcore is one of the world’s leading innovators in Artificial Intelligence compute. It is developing hardware, software and systems infrastructure that will unlock the next generation of AI breakthroughs and power the widespread adoption of AI solutions across every industry. As part of the SoftBank Group, Graphcore is a member of an elite family of companies responsible for some of the world’s most transformative technologies. Together, they share a bold vision: to enable Artificial Super Intelligence and ensure its benefits are accessible to everyone. Graphcore’s teams are drawn from diverse backgrounds and bring a broad range of skills and perspectives. A melting pot of AI research specialists, silicon designers, software engineers and systems architects, Graphcore enjoys a culture of continuous learning and constant innovation. Job Summary We are seeking a Senior Principal Network Engineer to help design, deploy, and optimize next‑generation AI data center networks. AI training and inference workloads require extremely high bandwidth, deterministic low latency, and zero‑packet‑loss networking environments. In this role, you will partner closely with the Network Architecture Lead to design and scale high‑performance computing (HPC) network fabrics supporting GPU clusters. You will work across hardware, networking, and AI application layers to ensure Graphcore’s large‑scale AI infrastructure operates at peak performance. The ideal candidate brings deep experience operating hyperscale or HPC data center networks and has expertise in high‑speed Ethernet fabrics, RDMA technologies, advanced automation, and telemetry systems. The Team The Data Center Network Engineering team designs and operates the high‑performance network fabrics that power Graphcore’s AI compute platforms. The team collaborates closely with hardware engineering, AI researchers, and infrastructure teams to build scalable networking environments optimized for distributed training and infe

PythonAIGoDevOps
C-
📍 New York, New York, United States· Full-time
✓ High-confidence listing

From $225K/yr

Quick readStrong listing-quality and freshness signals

CLEAR is building THE secure identity company of the future. Our mission is to make experiences safer and easier—physically and digitally. With more than 43 million Members and a growing network of partners across the world, CLEAR's secure identity platform is transforming the way people live, work, and travel. Whether it’s at the airport, stadium, or throughout your everyday life, CLEAR unlocks the magic of frictionless experiences. We are seeking a Senior Product Security Engineer to serve as a technical leader and strategic contributor within our Product Security team. This role goes beyond execution — you will drive the evolution of CLEAR’s application security posture by influencing architecture, shaping security engineering processes, and mentoring team members in security and engineering. You’ll lead security initiatives across the organization and help embed security into every stage of our software development lifecycle. What you'll do: Drive security strategy and implementation across all CLEAR products and engineering teams, ensuring consistent protection of customer and business-critical assets. Partner with engineering leadership to align application security initiatives with company-wide technology and product roadmaps, balancing innovation with risk mitigation. Provide technical leadership across CLEAR’s application security initiatives, guiding architecture, design, and development to meet high security standards. Serve as a trusted advisor to cross-functional teams — including Engineering, DevOps, Product, GRC, and IT — enabling secure-by-design practices across the organization. Design and drive implementation of scalable automated security controls and testing frameworks integrated into CLEAR’s CI/CD pipelines. Lead complex threat modeling, architecture reviews, and risk assessments across high-value systems and platforms, driving meaningful security outcomes. Engage with CLEAR's customers to provide insight and support their fraud and ident

JavaScriptPythonJavaCI/CD
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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -72.3%
Quick readStrong listing-quality and freshness signals

We believe that the way people interact with their finances will drastically improve in the next few years. We’re dedicated to empowering this transformation by building the tools and experiences that thousands of developers use to create their own products. Plaid powers the tools millions of people rely on to live a healthier financial life. We work with thousands of companies like Venmo, SoFi, several of the Fortune 500, and many of the largest banks to make it easy for people to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Seattle, Washington D.C., Raleigh, London, and Amsterdam. The Fraud Data team at Plaid builds the machine learning systems that power Plaid’s fraud detection products, leveraging insights from across Plaid’s network to help identify and stop fraud before it happens. Our team works across the full data science and machine learning lifecycle—from discovering new signals and experimenting with models to deploying and optimizing them in production. We continuously learn from real-world model performance and customer feedback to improve our systems and develop new ways to protect customers and consumers from evolving fraud threats. As a Senior Machine Learning Engineer on Plaid's Fraud Data team, you will develop models that improve fraud detection for our customers. You will identify predictive patterns in Plaid's network data and lead projects from initial experiments through model deployment and ongoing improvement. Investigate fraud patterns and model errors to identify new signals, improve detection, and expand coverage across customers and use cases. Develop training datasets and predictive features, addressing challenges such as incomplete labels, class imbalance, data leakage, and changing fraud behavior. Design, train, and tune model

PythonSQLAWSGit
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📍 New York, New York, United States· Full-time· Remote
✓ High-confidence listingCompany trend -72.3%
Quick readStrong listing-quality and freshness signals

We believe that the way people interact with their finances will drastically improve in the next few years. We’re dedicated to empowering this transformation by building the tools and experiences that thousands of developers use to create their own products. Plaid powers the tools millions of people rely on to live a healthier financial life. We work with thousands of companies like Venmo, SoFi, several of the Fortune 500, and many of the largest banks to make it easy for people to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Seattle, Washington D.C., Raleigh, London, and Amsterdam. We are the Fraud Data team within Plaid's Fraud organization. We leverage relationships and activity across Plaid’s network to develop machine learning models that help customers detect and prevent fraud while minimizing friction for legitimate users. Our team owns the full model lifecycle, from data processing and experimentation to feature pipelines, model serving, and monitoring. In this research role, you’ll partner closely with Machine Learning Engineers and Data Scientists to uncover new signals, explore and evaluate innovative modeling approaches, and translate promising research into production-ready solutions that strengthen fraud detection across Plaid’s network. As a Senior Research Scientist, you will lead applied research to develop next-generation fraud detection models across relational graphs, sequential events, images, and video data. You’ll design rigorous experiments and evaluation methodologies that reflect real-world fraud dynamics, while exploring state-of-the-art approaches such as Graph Neural Networks and Transformer-based foundation models. In close partnership with Machine Learning Engineers, you’ll translate promising research into production-ready solu

PythonAWSGitMachine Learning
B
📍 Berkeley, United States
✓ Quality checkedCompany trend +515.8%

Senior Low Observables (LO) Mission Systems Integration Engineer Company: The Boeing Company The Senior LO Mission Systems Integration Engineer will lead design, integration, analysis, test, and production activities for low observable materials, structures, apertures, sensors, and radomes for mission systems. The role requires strong technical leadership, independent execution of complex tasks, advanced use of computational electromagnetic (CEM) solvers, and the ability to produce and defend technical results with minimal oversight. Key Responsibilities Lead design, modeling, and analysis efforts for LO materials, coatings, structures, and integrated mission systems to meet signature reduction and performance requirements. Independently apply CEM solvers (e.g., FEKO, HFSS, CST, WIPL‑D, xFDTD, or equivalent) to model antennas, apertures, radomes, and LO treatments; perform design optimization and trade studies. Drive integration of LO treatments with mechanical, thermal, and sensor/antenna system constraints; identify and mitigate producibility, testability, and sustainment risks. Plan, execute, and oversee laboratory and field tests (anechoic chamber measurements, antenna/radome characterization, RCS measurements); lead data collection, reduction, and validation activities. Develop and validate predictive models, reconcile simulations with measurements, perform uncertainty quantification, and provide actionable recommendations to engineering and program leadership. Produce high-quality technical documentation: test plans, test reports, technical memoranda, design reviews, and customer briefings. Mentor and provide technical oversight to junior engineers and technicians; ensure adherence to engineering processes, qual

PythonRecruitment
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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -80.6%

$155K – $400K/yr

Quick readStrong listing-quality and freshness signals

About Sentry Software runs the world and the pace is faster than ever. Sentry helps developers fix errors and performance issues before users notice, so teams can spend less time firefighting and more time building. Trusted by 200,000+ organizations, Sentry is today’s application monitoring standard and our team is building its AI-native future. About the role The Events Analytics Platform (EAP) team is responsible for the infrastructure that powers all of Sentry's time-series data and searching capabilities across billions of events with sub-second latency. We started this initiative by building Snuba, the primary storage and query service for Sentry's event data powered by ClickHouse, and we are now focused on unlocking deeper visibility and reporting across the terabytes of event data our users generate. As a Senior Software Engineer, you will lead efforts to push the boundaries of data visibility at Sentry. You will do this by expanding the capabilities of our search infrastructure, building new capabilities on top of our state-of-the-art storage layer and increasing the performance and integrity of Sentry’s core data services. You will also help shape Infrastructure's technical direction at Sentry and collaborate with Product and other Engineering teams to turn that vision into a reality. If you want to solve the hard problems that come with scaling event data into the petabyte range, this could be the job for you. In this role you will: Expand EAP's ability to deliver data at world-class speed and reliability. Architect and automate services and systems to scale reliably under growing demand. Make architectural trade-offs that balance product requirements with engineering constraints. Maintain and grow the team's code quality initiatives by regularly reviewing code and contributing to design decisions. Lead design and discussions around deliverables the team is working towards. Improve the maintainability and developer experience of the codebases EAP owns. Exa

PythonSQLPostgreSQLRedis
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -82%

About the Team Security is at the foundation of OpenAI’s mission to ensure that artificial general intelligence benefits all of humanity. The Identity Infrastructure Engineering team sits at the core of this effort, designing and building the identity and access management solutions that protect our model weights, customer data, and critical systems across multiple cloud environments. We partner with teams across OpenAI—Applied Engineering, Research, IT, and Security—to provide a secure and scalable platform for permissioning, orchestration, and innovative AI research. About the Role We’re looking for a Staff+ Software Engineer to help build and evolve the identity infrastructure that supports OpenAI’s research, engineering, and internal platforms. This role sits at the intersection of cloud infrastructure, identity systems, and software engineering. You’ll work across production systems, infrastructure-as-code, cloud control planes, identity providers, and operational infrastructure to build secure, scalable, and reliable systems used broadly across the company. The ideal candidate has experience building and operating large-scale, mission-critical systems with strong reliability and security requirements, and is comfortable writing production code, designing distributed systems, and driving ambiguous projects from 0 to 1 while building the operational rigor needed to run critical infrastructure over time. In this role, you will: Lead the architecture, development, and operation of identity infrastructure that spans cloud platforms, internal systems, and critical engineering services. Design and evolve systems for authentication, authorization, access governance, auditability, and policy enforcement with a strong focus on reliability, scalability, and secure-by-default design. Build foundational infrastructure and platform capabilities that are broadly used across engineering, research, and security teams. Improve the reliability, observability, performance, and op

PythonAWSRestAI
B
📍 Daytona Beach, FL, United States
✓ High-confidence listingCompany trend +515.8%
Quick readStrong listing-quality and freshness signals

Senior Software Engineer Mission Systems Software Developer Company: The Boeing Company The Boeing Company has an exciting opportunity for a Senior Software Engineer Mission Systems Software Developer (Level 5) to join Boeing Defense, Space & Security (BDS) in Daytona Beach, Florida . BDS is a global leader in the development, production, maintenance and enhancement of fixed-wing and rotary wing aircraft, commercial and government satellites, human spaceflight programs and weapons. Key markets include aeronautics, space and weapons. Core capabilities are in development, production and mission enabling upgrades of integrated solutions. BDS delivers the most digitally advanced, simply and efficiently produced and intelligently supported solutions to its customers. Daytona Beach is the company's newest state-of-the-art facility focused on engineering excellence. Florida offers no state income tax and a variety of other desirable personal and financial benefits. This position will include developing software and software tests throughout all phases of the software development life cycle (requirements, architecture, implementation, and verification). The software engineer will develop software in a Continuous Integration / Continuous Deployment (CI/CD) DevSecOps software build pipeline using an agile methodology focused on code quality, security and automation. Position Responsibilities: Develop Participates in use case development of software requirements Ability to lead activities to develop, document and maintain software architecture, requirements, algorithms, interfaces and designs for mission systems software Leads development of code and integration of complex Mission Systems softwar

PythonJavaGitLinux
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📍 New York, NY, United States· Full-time
✓ High-confidence listing

$225K – $300K/yr

Quick readStrong listing-quality and freshness signals

CLEAR is building THE secure identity company of the future. Our mission is to make experiences safer and easier—physically and digitally. With more than 43 million Members and a growing network of partners across the world, CLEAR's secure identity platform is transforming the way people live, work, and travel. Whether it’s at the airport, stadium, or throughout your everyday life, CLEAR unlocks the magic of frictionless experiences. Today, CLEAR is well-known as a leader in digital and biometric identification, reducing friction for our members wherever an ID check is needed. We’re looking for a Senior Software Engineer to establish our Observability framework and foundations. You will join us to accelerate building and scaling our innovative systems that support our growing identity platform. You will drive on Observability best practices to find and fix gaps in our observability and our overall systems. You will also lead practices such as load testing, capacity planning, game days, chaos testing, and incident post-mortems. What You Will Do: Embed within the Engineering pillar to deeply understand the product and implement observability across all key flows Facilitate and build load testing cases, ensuring we understand the limits and scaling factors of our services and systems Contribute to observability and support the design of new services and systems, ensuring highly reliable and scalable concepts are implemented Build and lead practices such as game days, chaos engineering, and failure analysis Build long-term capacity plans, with an eye toward reliability and cost-efficiency Who You Are: 6+ experience writing production-grade software in a modern language, such as Java and Python. Strong knowledge of distributed systems concepts (think CAP theorem), microservices architecture, and distributed tracing . Experience with modern observability systems such as Datadog. Experience with performance debugging tools and patterns. You should be able to read a f

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