Jobs in United States

Lead Senior Python Engineer in United States

2,434 active opportunities · Updated October 2026

Explore current lead senior python engineer jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -85.2%

From $80K/yr

Quick readStrong listing-quality and freshness signals

The GTM Strategy & Operations Associate will join a global team driving Datadog’s next phase of growth. We’re interdisciplinary thinkers leveraging diverse business backgrounds in tech, management consulting, investment banking and business development to accelerate Datadog’s global growth. We work directly with Datadog’s most senior leaders to set corporate strategy, improve efficiency across the business, support data-driven decision-making, own complex operations, and more. In this role, you will identify opportunities for revenue growth and design strategic go-to-market (GTM) initiatives by evaluating business tradeoffs and partnering with senior leaders to shape GTM strategy. You will drive key planning processes, including capacity planning and quota planning, optimization and expansion strategies, and KPI design and measurement. Additionally, you will lead critical operational initiatives and long-term strategic projects that improve execution and help build the foundation for the company's continued growth. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What you’ll do: Strategic roadmap development: Develop short- and long-term GTM strategies by identifying growth opportunities, setting business priorities, and aligning sales and growth targets. Lead strategic planning initiatives, including headcount and KPI planning, incentive design, and cross-functional projects to improve execution and accelerate revenue growth. Global quota ownership: Own quotas for the global Sales organization – build and maintain quota models, adjust them throughout the year in response to org changes, and drive stakeholder alignment along the way. GTM analysis, reporting, and modeling: Analyze sales and GTM data to identify trends and understand efficiency by channel. Develop data

PythonSQLAIGo
S
📍 Austin, TX, United States· Full-time
✓ Quality checkedCompany trend -92.9%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. We are hiring a Senior Technical Architect for our Services Delivery team. Our SD organization partners with customers across every stage of their data and AI journey, from initial implementation through long-term platform strategy. In this role, you will own the technical delivery and outcome for complex, high-priority engagements, serve as the most senior technical voice in the room, and shape how our customers use Snowflake to drive real business transformation. AS A SENIOR TECHNICAL ARCHITECT AT SNOWFLAKE, YOU WILL: Customer Leadership and Advisory Lead customer engagements as the primary technical authority, owning architecture decisions and driving measurable outcomes across complex, multi-workstream implementations Partner with customer executives and senior technical leadership to define platform strategy, develop long-term roadmaps, and align Snowflake capabilities to business objectives Translate ambiguous business problems into well-defined, scalable technical solutions, with clear delivery paths and risk-mitigation strategies Serve as the trusted escalation point for technical challenges within engagements, unblocking delivery teams and resolving architectural issues Technical Architecture and Delivery Architect and implement end-to-end AI/ML solutions on Snowfl

PythonSQLAWSAzure
S
📍 New York, United States· Full-time
✓ Quality checkedCompany trend -92.9%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. We are hiring a Senior Technical Architect for our Services Delivery team. Our SD organization partners with customers across every stage of their data and AI journey, from initial implementation through long-term platform strategy. In this role, you will own the technical delivery and outcome for complex, high-priority engagements, serve as the most senior technical voice in the room, and shape how our customers use Snowflake to drive real business transformation. AS A SENIOR TECHNICAL ARCHITECT AT SNOWFLAKE, YOU WILL: Customer Leadership and Advisory Lead customer engagements as the primary technical authority, owning architecture decisions and driving measurable outcomes across complex, multi-workstream implementations Partner with customer executives and senior technical leadership to define platform strategy, develop long-term roadmaps, and align Snowflake capabilities to business objectives Translate ambiguous business problems into well-defined, scalable technical solutions, with clear delivery paths and risk-mitigation strategies Serve as the trusted escalation point for technical challenges within engagements, unblocking delivery teams and resolving architectural issues Technical Architecture and Delivery Architect and implement end-to-end AI/ML solutions on Snowfl

PythonSQLAWSAzure
S
📍 New York, United States· Full-time
✓ Quality checkedCompany trend -92.9%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. We are hiring a Senior Technical Architect for our Services Delivery team. Our SD organization partners with customers across every stage of their data and AI journey, from initial implementation through long-term platform strategy. In this role, you will own the technical delivery and outcome for complex, high-priority engagements, serve as the most senior technical voice in the room, and shape how our customers use Snowflake to drive real business transformation. AS A SENIOR TECHNICAL ARCHITECT AT SNOWFLAKE, YOU WILL: Customer Leadership and Advisory Lead customer engagements as the primary technical authority, owning architecture decisions and driving measurable outcomes across complex, multi-workstream implementations Partner with customer executives and senior technical leadership to define platform strategy, develop long-term roadmaps, and align Snowflake capabilities to business objectives Translate ambiguous business problems into well-defined, scalable technical solutions, with clear delivery paths and risk-mitigation strategies Serve as the trusted escalation point for technical challenges within engagements, unblocking delivery teams and resolving architectural issues Technical Architecture and Delivery Architect and implement end-to-end AI/ML solutions on Snowfl

PythonSQLAWSAzure
S
📍 New York, United States· Full-time
✓ Quality checkedCompany trend -92.9%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. We are hiring a Senior Technical Architect for our Services Delivery team. Our SD organization partners with customers across every stage of their data and AI journey, from initial implementation through long-term platform strategy. In this role, you will own the technical delivery and outcome for complex, high-priority engagements, serve as the most senior technical voice in the room, and shape how our customers use Snowflake to drive real business transformation. AS A SENIOR TECHNICAL ARCHITECT AT SNOWFLAKE, YOU WILL: Customer Leadership and Advisory Lead customer engagements as the primary technical authority, owning architecture decisions and driving measurable outcomes across complex, multi-workstream implementations Partner with customer executives and senior technical leadership to define platform strategy, develop long-term roadmaps, and align Snowflake capabilities to business objectives Translate ambiguous business problems into well-defined, scalable technical solutions, with clear delivery paths and risk-mitigation strategies Serve as the trusted escalation point for technical challenges within engagements, unblocking delivery teams and resolving architectural issues Technical Architecture and Delivery Architect and implement end-to-end AI/ML solutions on Snowfl

PythonSQLAWSAzure
S
📍 Washington, United States· Full-time
✓ Quality checkedCompany trend -92.9%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. We are hiring a Senior Technical Architect for our Services Delivery team. Our SD organization partners with customers across every stage of their data and AI journey, from initial implementation through long-term platform strategy. In this role, you will own the technical delivery and outcome for complex, high-priority engagements, serve as the most senior technical voice in the room, and shape how our customers use Snowflake to drive real business transformation. AS A SENIOR TECHNICAL ARCHITECT AT SNOWFLAKE, YOU WILL: Customer Leadership and Advisory Lead customer engagements as the primary technical authority, owning architecture decisions and driving measurable outcomes across complex, multi-workstream implementations Partner with customer executives and senior technical leadership to define platform strategy, develop long-term roadmaps, and align Snowflake capabilities to business objectives Translate ambiguous business problems into well-defined, scalable technical solutions, with clear delivery paths and risk-mitigation strategies Serve as the trusted escalation point for technical challenges within engagements, unblocking delivery teams and resolving architectural issues Technical Architecture and Delivery Architect and implement end-to-end AI/ML solutions on Snowfl

PythonSQLAWSAzure
O
📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -82%
Quick readStrong listing-quality and freshness signals

About the Team OpenAI’s People team hires, engages, and retains world-class talent to safely build and deploy AGI that benefits all of humanity. The People Analytics team helps leaders make rigorous, evidence-based talent decisions and ensures that the systems supporting those decisions are valid, reliable, fair, and accountable. About the Role As a People Data Scientist focused on AI fairness and bias testing, you will help establish how OpenAI evaluates AI-assisted People systems and high-impact talent processes. You will design and conduct rigorous assessments to identify, measure, and mitigate potential bias across the lifecycle of models, agents, decision-support tools, and automated workflows. Your work will span the entire employee life-cycle, such as hiring, performance, promotion, employee development, workforce planning, etc. You will evaluate both technical systems and the broader human-AI decision processes in which they operate, examining not only model performance but also data quality, measurement validity, differential outcomes, human oversight, and unintended consequences. We’re looking for an experienced data scientist or applied researcher who can translate complex fairness questions into defensible evaluation strategies, scalable testing infrastructure, and clear recommendations for technical teams and senior leaders. This role is preferred to be based in San Francisco, CA. In this role, you will: Define and lead fairness and bias-testing strategies for AI-assisted People processes, models, agents, and decision-support systems from development through deployment and ongoing monitoring. Design rigorous algorithmic audits and validation studies, including adverse-impact analysis, subgroup and intersectional evaluation, error-rate analysis, calibration, measurement invariance, reliability, criterion-related validity, and sensitivity testing. Identify the appropriate fairness criteria for each use case, evaluate tradeoffs among competing definitions

PythonSQLAWSRest
S
📍 Bellevue, Washington, United States· Full-time
✓ Quality checkedCompany trend -92.9%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. ABOUT THE ROLE Snowpark is how developers run distributed Python, Java, and Scala workloads directly on the Snowflake platform — securely, at scale, and without moving data. It is one of Snowflake's most differentiated and fastest-growing products, and as workloads become agent-driven — where Python is the default — its growth is only accelerating. Having expanded from structured data into semi-structured and ETL workloads, Snowpark is now entering its most exciting phase: unstructured, multimodal, and agentic AI data processing. We are looking for a Principal Product Manager to own Snowpark and lead this next chapter. This is a general-manager-style role: you will own the strategy, growth, and go-to-market for a critical product line, acting as an entrepreneur with the autonomy to propose and launch multiple 0→1 bets on top of an already highly successful product. You will be the most senior PM on the product, with a clear path to lead the Snowpark PM team as you demonstrate impact. AS A PRINCIPAL PM AT SNOWFLAKE, YOU WILL: Define the Mission: Own the end-to-end, multi-year strategy and roadmap for Snowpark as the standard for distributed Python, Java, and Scala processing on the data platform. Lead the 0→1: Drive the expansion into unstructured/multimodal data processing

PythonJavaAIGo
M
📍 San Francisco Bay Area, California, United States· Full-time
✓ Quality checkedCompany trend -100%

What you'll do Run human-subjects recording sessions end-to-end: participant prep and fitting, sensor configuration and calibration, stimulus delivery, real-time signal monitoring, and session documentation. Own daily system QC for a one-of-a-kind sensing instrument: baseline noise recordings, per-sensor health checks, log review, and escalation of anomalies before they touch a dataset. Own participant operations: recruitment coordination, scheduling, screening, consent, and compliant handling of participant records. Stand up and maintain the operational backbone of the program: SOPs for acquisition, QC, and participant workflows — documentation that survives you. Handle first-pass data operations: file conversion, organization, metadata, and quality review in Python. Partner daily with the program lead to refine acquisition protocols and improve system performance over time. What we're looking for Hands-on experience acquiring physiological or imaging data from human participants in a clinical or research setting Obsessive consistency and attention to detail: you notice when something is off and you don't let it slide. Professional, patient, and calm with research participants — sessions succeed or fail on how people feel in the room. Basic scripting ability (Python and/or shell) for QC and data-handling tasks, or clear aptitude and motivation to build it. High ownership of the unglamorous parts: scheduling, documentation, tidy data hygiene. Discretion — parts of this program are not yet public. We'll walk you through the specifics, including the exact technology you'd be operating, in the first conversation. Useful experience Controlled or low-noise recording environments and highly sensitive instrumentation. Physiological signal-processing tools in Python. Human-subjects research administration (IRB protocols, consent workflows). Research studies involving structured tasks or sensory protocols with human participants.

C
📍 Tampa Florida United States, United States
✓ High-confidence listingCompany trend +800%
Quick readStrong listing-quality and freshness signals

The Applications Development Technology Senior Lead Analyst is a senior level position responsible for establishing and implementing new or revised application systems and programs in coordination with the Technology Team. The overall objective of this role is to lead applications systems analysis and programming activities. Responsibilities: Lead the architecture, design, development, and delivery of enterprise UI applications. Strong hands-on experience with Angular and Ext JS for developing scalable and responsive user interfaces. Strong experience with Java and Spring Boot for designing and developing backend services and APIs. Experience deploying, supporting, and troubleshooting applications in ECS/containerized environments . Define application architecture, technical standards, reusable components, and development best practices. Provide technical leadership to development teams, including design reviews, code reviews, performance optimization, and troubleshooting . Strong understanding of CI/CD pipelines , including automated build, testing, deployment, and release processes. Hands-on experience with GitHub , including source-code management, branching strategies, pull requests, code reviews, and integration with CI/CD pipelines. Strong knowledge of open-source technologies and frameworks , with hands-on implementation experience. Ability to evaluate and select appropriate open-source libraries, frameworks, and tools , considering security, licensing, maintainability, vulnerabilities, and enterprise standards. Drive application modernization, technical improvements, and adoption of engineering best practices. Work closely with architects, developers, infrastructure teams, product owners, and business stakeholders to deliver solutions successfully. Prov

JavaAngularGitArtificial Intelligence
C
📍 Monroeville, United States
✓ Quality checkedCompany trend +340.2%

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Position Summary As the Senior Lead Coordinator you will be responsible for implementing and maintaining comprehensive billing review processes. You will identify and quantify trends/issues and effectively communicate/report them to the appropriate members of the management team and payer business partners along with the potential impact. You will assist leadership in building and maintaining a high performing highly engaged team. In this role you will also provide excellent mentorship and support to your colleagues as well as design and implement training classes. The key responsibilities of the Medical Revenue Cycle Senior Lead Coordinator are: Review and analyze patient profiles, benefits, and prior authorizations to identify potential issues affecting clean claims. Collaborate with clinical and administrative teams to ensure accurate documentation is maintained and available for claims processing. Monitor claims submissions and follow up on pending claims to expedite resolution and payment. Identify trends in claims denials and develop strategies for improvement. Conduct training sessions for staff on best practices for claims submissions and compliance. Maintain up-to-date knowledge of insurance policies, regulations, and healthcare trends that impact claims

C
📍 Nc Charlotte, United States
✓ High-confidence listingCompany trend +800%
Quick readStrong listing-quality and freshness signals

The AML Risk Management Senior Lead Analyst is a senior level position responsible for establishing internal procedures to prevent money laundering and assist in all matters concerning financial crimes in coordination with the broader AML team. The overall objective is to utilize established disciplinary knowledge to identify inconsistencies in data or result and formulate strategic recommendations on policies, procedures, and practices. Responsibilities: Execute and implement firm-wide AML risk management policy and strategic direction for the Markets Institutional line of business. Maintain AML compliance program for the business including assessment of risks and the development of policies, procedures, and governance, including those pertaining to an institutional broker dealer. Identify and assess risk, vulnerabilities, and opportunities for efficient and effective risk coverage. Work within team and across business/functional line management to assess complex issues, structure potential solutions, and drive effective resolution within permissible statutory and regulatory frameworks. Analyze data, prepare and present regional/global reports related to AML risk assessments. Monitor AML related issues and escalations with senior management and global partners. Evaluate and respond to escalated matters, further escalate as required, and advise senior management on next steps as needed. Appropriately assess risk when business decisions are made, demonstrating particular consideration for the firm's reputation and safeguarding Citigroup, its clients and assets, by driving compliance with applicable laws, rules and regulations, adhering to Policy, applying sound ethical judgment regarding personal behavior, conduct and business practices, and escalating, managing and reporting control issues with transparency. Qualifications

Artificial IntelligenceAI
B
📍 Kirtland Afb, NM, United States
✓ High-confidence listingCompany trend +515.8%
Quick readStrong listing-quality and freshness signals

Electronics Test and Evaluation Lab Technician (Senior or Lead) Company: The Boeing Company Boeing Defense, Space and Security (BDS) is looking for a Senior or Lead Electronics Test and Evaluation Lab Technician (Level 4 or 5) to join our team at the Starfire Optical Range on Kirtland AFB in Albuquerque, New Mexico. The role supports the Air Force Research Lab in their advancement of Space Domain Awareness capabilities using ground-based telescopes. Starfire Optical Range is a world class research facility with recognized achievements in adaptive optics, enabled by the quality, enthusiasm, and dedication of our entire team. Our team consists of engineers and technicians in all disciplines required to plan, design, integrate, and test complex optical, electronic, laser systems to achieve research objectives. Position Responsibilities: Plans, conducts and documents complex tests on products, systems, components, materials, and manufacturing processes and technologies. Designs, fabricates, builds and analyzes test systems, materials, components, software and methodologies. Coordinates test requirements, determines test methods and capabilities. Conducts system test preparations by guiding system integration, fabrication, modification, setup, checkout and teardown. Performs test article configuration control. Conducts complex tests, analyzes data and documents results; participates in test readiness reviews. Identifies and resolves test anomalies. Troubleshoots and resolves complex laboratory and test-related problems. Coordinates test laboratory activities, maintenance and repairs, and

Recruitment
B
📍 Berkeley, United States
✓ Quality checkedCompany trend +515.8%

Cloud Platform Administrator (Mid-Level, Senior or Lead) **Sign on Bonus Potential** Company: The Boeing Company The Boeing Company’s Specialized United States Infrastructure Operations is currently seeking a Cloud Platform Administrator (Mid-Level, Senior or Lead) to join the team in Berkeley, MO; Seattle, WA; or Daytona Beach, FL . The Infrastructure team is seeking a skilled platform engineer to help build and operate the cloud platform services that host critical enterprise applications and software toolchains. In this role, the selected candidate will focus on the shared platform capabilities that enable teams to deploy, run, and maintain containerized and cloud-hosted solutions in a consistent and supportable manner. As both an individual contributor and technical leader, this position will help define and implement platform standards for Kubernetes, container hosting, deployment automation, configuration management, and operational support. This role is focused on platform reliability, repeatability, scalability, and service enablement, rather than custom application software development. Position Responsibilities: Design, implement, and maintain cloud platform services supporting Kubernetes, containers, ingress, storage integration, secrets management, and service connectivity Build and sustain reusable deployment patterns for Commercial-Off-The-Shelf (COTS), Open Source Software (OSS), and internally customized applications Develop and maintain automation for platform provisioning, upgrades, patching, and lifecycle support Manage cluster lifecycle activities including: Cluster upgrades Node management <

AWSAzureDockerKubernetes
B
📍 Berkeley, United States
✓ Quality checkedCompany trend +515.8%

Cloud Infrastructure Administrator (Mid-Level, Senior or Lead) **Sign on Bonus Potential** Company: The Boeing Company The Boeing Company’s Specialized United States Infrastructure Operations organization is currently seeking a Cloud Infrastructure Administrator (Mid-Level, Senior or Lead) to join the team in Berkeley, MO; Seattle, WA; or Daytona Beach, FL . The Infrastructure team is seeking an experienced cloud infrastructure professional to help design, build, and sustain the foundational cloud environment supporting critical program needs. In this role, the selected candidate will help establish and operate secure, scalable, and resilient cloud infrastructure environments in Microsoft Azure to enable enterprise applications, software toolchains, and digital engineering workloads. As both an individual contributor and technical leader, this position will work across network, computer, storage, identity, security, and automation domains to deliver repeatable cloud infrastructure patterns and operational excellence. This role is focused on infrastructure operations, sustainment, automation, and reliability, rather than application software development. Position Responsibilities: Design, implement, and maintain Microsoft Azure-based infrastructure solutions including networking, compute, storage, identity integration, and supporting services Develop and maintain Infrastructure as Code (IaC) and configuration automation solutions using Terraform, Ansible, PowerShell, and Bash Implement cloud policies to enforce security, ensure regulatory compliance, and manage user access Build repeatable landing zones and cloud infrastructure patterns that support mul

AzureTerraformAnsibleSap
🔔

Get new lead senior python engineer jobs in United States by email

Daily job updates · Unsubscribe anytime