Jobs in United States

Lead Senior Sr Software Engineer 2c Backend in United States

2,624 active opportunities · Updated October 2026

Explore current lead senior sr software engineer 2c backend jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

Hiring demand

51/100

steady · 561 related jobs

Hiring trend

-78.6%

Job postings compared with the previous 30 days

Remote options

15.7%

Share of matching jobs listed as remote

Typical salary

$177.2K – $177.2K/yr

Based on 31 salary observations

V
📍 United States· Full-time
✓ Quality checkedCompany trend -92.7%

At Vanta, our mission is to help businesses earn and prove trust. We believe that security should be monitored and verified continuously, and we empower companies to practice better security and prove it with ease. Vanta has a kind and talented team, and while some have prior security experience, many have been successful at Vanta without it. Vanta's Corporate Engineering team is the infrastructure layer that keeps 1,500+ people connected, secure, and moving fast. AI is now central to how that happens, and this role leads the team that owns the backbone underneath it. Corporate Engineering owns the shared AI platform for Vanta's internal systems: identity and access for AI tools, cost visibility and controls, sanctioned tooling and guardrails, and the enablement that helps people use those tools well. We do not own product AI, which stays with Engineering, and we do not replace the AI work happening inside individual departments. We build the engineering layer that makes all of it safer, cheaper, and better supported. The company has moved fast. AI assistant use is widespread across every function, MCP infrastructure is live and self-serve company-wide, internal apps ship on a hosted platform, and AI spend has grown to the point where attribution and guardrails genuinely matter. What does not exist yet is a single owner for that platform layer. That is this role. As Sr. Manager, AI Engineering, you will lead a small, senior team, write the charter for what Corporate Engineering owns versus enables, and build the platform that lets the rest of Vanta adopt AI quickly without accumulating cost, risk, or duplication. What you’ll do as a Senior Manager, AI Corporate Engineering at Vanta: Lead, coach, and grow a senior team spanning platform engineering and technical program management. Set clear direction, hold a high bar, and give the team explicit permission to push back with data. Own the AI access layer end to end: identity and authentication for AI tools, connector

CI/CDRestAIGo
V
📍 United States· Full-time
✓ Quality checkedCompany trend -92.7%

At Vanta, our mission is to help businesses earn and prove trust. We believe that security should be monitored and verified continuously, and we empower companies to practice better security and prove it with ease. Vanta has a kind and talented team, and while some have prior security experience, many have been successful at Vanta without it. Vanta's Corporate Engineering team is the infrastructure layer that keeps 1,500+ people connected, secure, and moving fast. This role leads the shift from a reactive support function to a platform function the whole company relies on. Corporate Engineering owns the systems, tooling, and access infrastructure Vanta runs on. From identity and device management to AI tooling infrastructure and ITSM, CE makes sure Vanta's people have the right access, the right tools, and the right guardrails on day one and every day after. CE is at an inflection point. The company has scaled quickly, AI tooling is live company-wide, and the team is ready for a leader who sets technical direction, establishes clear ownership, and builds the leadership layer beneath them. As Sr. Manager, Systems Engineering, you will lead a team of experienced engineers, own several of the company's highest-priority platform initiatives, and make CE a function the rest of Vanta builds on rather than routes around. What you’ll do as a Senior Manager, Systems Engineering at Vanta: Lead, coach, and grow a team of systems engineers and a tech lead. Set clear expectations, hold a high bar, and develop the people who build Vanta's most critical internal systems. Own joiner, mover, and leaver automation end to end in Okta Workflows, so access is correct on day one, follows people through role changes, and closes completely on departure, including API keys and service credentials. Build and own device assurance across macOS and Windows, defining OS, browser, and device-state policy ahead of enforcement rather than in response to it. Rationalize the ITSM estate so self-servi

ReactGitRestAI
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $176.5K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. Roblox is building the future of human connection through play. As a Senior Growth Marketing Manager, you will play a critical role in scaling Roblox's global growth engine, helping millions of users discover, engage with, and return to Roblox. This role sits at the intersection of marketing, product, data science, and engineering. You will lead high-impact growth initiatives spanning user acquisition, lifecycle marketing, personalization, creator growth, and product-led growth. You will be responsible for identifying new growth opportunities, designing and executing experiments, influencing product strategy, and scaling programs that drive measurable business impact. This is a highly cross-functional role for someone who combines analytical rigor, strong growth instincts, operational excellence, and the ability to influence across teams. You will report to Sr Manager, Growth Marketing. You will: Own and Scale Growth Programs Lead end-to-end growth initiatives across user acquisition, reactivation, paid influencer, and product-led growth programs. Manage and optimize multimillion-dollar marketing investments across ad platforms including but not limited to Google, YouTube, Meta, TikTok, App

ReactSQLAWSGit
P
Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, United States· Full-time· Remote
✓ High-confidence listingCompany trend -86.4%

From $163.6K/yr

Quick readStrong listing-quality and freshness signals

About Pinterest: Millions of people around the world come to our platform to find creative ideas, dream about new possibilities and plan for memories that will last a lifetime. At Pinterest, we’re on a mission to bring everyone the inspiration to create a life they love, and that starts with the people behind the product. Discover a career where you ignite innovation for millions, transform passion into growth opportunities, celebrate each other’s unique experiences and embrace the flexibility to do your best work. Creating a career you love? It’s Possible. At Pinterest, AI isn't just a feature, it's a powerful partner that augments our creativity and amplifies our impact, and we’re looking for candidates who are excited to be a part of that. To get a complete picture of your experience and abilities, we’ll explore your foundational skills and how you collaborate with AI. Through our interview process, what matters most is that you can always explain your approach, showing us not just what you know, but how you think. You can read more about our AI interview philosophy and how we use AI in our recruiting process here . As a Sr. Staff Technical Program Manager for Search Signals at Pinterest, you will lead company-level programs that are foundational to Pinterest’s strategic transformation into a shopping and inspiration platform. This role is responsible for driving innovation and execution across offsite signals, content understanding, and relevance, with direct impact on multiple company OKRs. You will operate at the intersection of technical depth, cross-org influence, and long-term business strategy, shaping the future of search and personalization at Pinterest. What you’ll do: Strategic Leadership & Vision Envision and trailblaze the company’s approach to leveraging offsite and onsite signals, anticipating future business, technical, and regulatory challenges. Drive the creation and evolution of the company-wide roadmap for signals,

AWSRestAIGo
S
📍 Austin, TX, United States· Full-time
✓ Quality checkedCompany trend -93.3%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. We are hiring a Senior Technical Architect for our Services Delivery team. Our SD organization partners with customers across every stage of their data and AI journey, from initial implementation through long-term platform strategy. In this role, you will own the technical delivery and outcome for complex, high-priority engagements, serve as the most senior technical voice in the room, and shape how our customers use Snowflake to drive real business transformation. AS A SENIOR TECHNICAL ARCHITECT AT SNOWFLAKE, YOU WILL: Customer Leadership and Advisory Lead customer engagements as the primary technical authority, owning architecture decisions and driving measurable outcomes across complex, multi-workstream implementations Partner with customer executives and senior technical leadership to define platform strategy, develop long-term roadmaps, and align Snowflake capabilities to business objectives Translate ambiguous business problems into well-defined, scalable technical solutions, with clear delivery paths and risk-mitigation strategies Serve as the trusted escalation point for technical challenges within engagements, unblocking delivery teams and resolving architectural issues Technical Architecture and Delivery Architect and implement end-to-end AI/ML solutions on Snowfl

PythonSQLAWSAzure
S
📍 New York, United States· Full-time
✓ Quality checkedCompany trend -93.3%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. We are hiring a Senior Technical Architect for our Services Delivery team. Our SD organization partners with customers across every stage of their data and AI journey, from initial implementation through long-term platform strategy. In this role, you will own the technical delivery and outcome for complex, high-priority engagements, serve as the most senior technical voice in the room, and shape how our customers use Snowflake to drive real business transformation. AS A SENIOR TECHNICAL ARCHITECT AT SNOWFLAKE, YOU WILL: Customer Leadership and Advisory Lead customer engagements as the primary technical authority, owning architecture decisions and driving measurable outcomes across complex, multi-workstream implementations Partner with customer executives and senior technical leadership to define platform strategy, develop long-term roadmaps, and align Snowflake capabilities to business objectives Translate ambiguous business problems into well-defined, scalable technical solutions, with clear delivery paths and risk-mitigation strategies Serve as the trusted escalation point for technical challenges within engagements, unblocking delivery teams and resolving architectural issues Technical Architecture and Delivery Architect and implement end-to-end AI/ML solutions on Snowfl

PythonSQLAWSAzure
S
📍 New York, United States· Full-time
✓ Quality checkedCompany trend -93.3%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. We are hiring a Senior Technical Architect for our Services Delivery team. Our SD organization partners with customers across every stage of their data and AI journey, from initial implementation through long-term platform strategy. In this role, you will own the technical delivery and outcome for complex, high-priority engagements, serve as the most senior technical voice in the room, and shape how our customers use Snowflake to drive real business transformation. AS A SENIOR TECHNICAL ARCHITECT AT SNOWFLAKE, YOU WILL: Customer Leadership and Advisory Lead customer engagements as the primary technical authority, owning architecture decisions and driving measurable outcomes across complex, multi-workstream implementations Partner with customer executives and senior technical leadership to define platform strategy, develop long-term roadmaps, and align Snowflake capabilities to business objectives Translate ambiguous business problems into well-defined, scalable technical solutions, with clear delivery paths and risk-mitigation strategies Serve as the trusted escalation point for technical challenges within engagements, unblocking delivery teams and resolving architectural issues Technical Architecture and Delivery Architect and implement end-to-end AI/ML solutions on Snowfl

PythonSQLAWSAzure
S
📍 New York, United States· Full-time
✓ Quality checkedCompany trend -93.3%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. We are hiring a Senior Technical Architect for our Services Delivery team. Our SD organization partners with customers across every stage of their data and AI journey, from initial implementation through long-term platform strategy. In this role, you will own the technical delivery and outcome for complex, high-priority engagements, serve as the most senior technical voice in the room, and shape how our customers use Snowflake to drive real business transformation. AS A SENIOR TECHNICAL ARCHITECT AT SNOWFLAKE, YOU WILL: Customer Leadership and Advisory Lead customer engagements as the primary technical authority, owning architecture decisions and driving measurable outcomes across complex, multi-workstream implementations Partner with customer executives and senior technical leadership to define platform strategy, develop long-term roadmaps, and align Snowflake capabilities to business objectives Translate ambiguous business problems into well-defined, scalable technical solutions, with clear delivery paths and risk-mitigation strategies Serve as the trusted escalation point for technical challenges within engagements, unblocking delivery teams and resolving architectural issues Technical Architecture and Delivery Architect and implement end-to-end AI/ML solutions on Snowfl

PythonSQLAWSAzure
S
📍 Washington, United States· Full-time
✓ Quality checkedCompany trend -93.3%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. We are hiring a Senior Technical Architect for our Services Delivery team. Our SD organization partners with customers across every stage of their data and AI journey, from initial implementation through long-term platform strategy. In this role, you will own the technical delivery and outcome for complex, high-priority engagements, serve as the most senior technical voice in the room, and shape how our customers use Snowflake to drive real business transformation. AS A SENIOR TECHNICAL ARCHITECT AT SNOWFLAKE, YOU WILL: Customer Leadership and Advisory Lead customer engagements as the primary technical authority, owning architecture decisions and driving measurable outcomes across complex, multi-workstream implementations Partner with customer executives and senior technical leadership to define platform strategy, develop long-term roadmaps, and align Snowflake capabilities to business objectives Translate ambiguous business problems into well-defined, scalable technical solutions, with clear delivery paths and risk-mitigation strategies Serve as the trusted escalation point for technical challenges within engagements, unblocking delivery teams and resolving architectural issues Technical Architecture and Delivery Architect and implement end-to-end AI/ML solutions on Snowfl

PythonSQLAWSAzure
S
📍 Menlo Park, California, United States· Full-time
✓ Quality checkedCompany trend -93.3%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. About the Role Snowflake is transforming how enterprise Procure to Pay operates — and we're looking for a senior operations leader to help us execute on that vision. This is not a role for someone who wants to maintain the status quo. We have agentic AI projects in flight, a best-in-class technology stack, and a team that is motivated to build something the industry hasn't seen before. We need someone who can run the operation at a high level while simultaneously driving execution on the automation and AI initiatives already on our roadmap. As Sr. Manager of Procure to Pay Operations, you will own the operational performance of our end-to-end P2P function — spanning Procurement, Accounts Payable, Strategic Sourcing, Travel & Expense, and Global Contracts. You will report directly to the Chief Procurement Officer and serve as the operational backbone of a global, fast-moving team. What You'll Do Own P2P Operations End to End Lead day-to-day operations across Procurement, AP, Strategic Sourcing, T&E, and Global Contracts Ensure SLA performance, approval cycle times, and process compliance meet or exceed targets across all functions Establish clear ownership, operating rhythms, and accountability across a globally distributed team Serve as the primary operational escal

AWSAIGoRust
G
📍 California, Foster City, United States
✓ High-confidence listingCompany trend +5.2%

$169.3K – $219.1K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Senior Scientist, Purification Process Development (Pivotal & Commercial) role will be responsible for leading aspects of purification development including commercial process development and process characterization for multiple biologics programs during pivotal phases (phases II/III and post-launch). In addition, this role is also expected to lead/support technology transfer, participate in purification and cross-functional initiatives, and support purification regulatory documentation. Key Responsibilities: Design experiments and demonstrate hands-on technical leadership of all aspects of purification process development including chromatography, TFF, virus f

Supply ChainRecruitment
G
📍 California, El Segundo, United States
✓ High-confidence listingCompany trend +5.2%

$115.3K – $149.2K/yr

Quick readStrong listing-quality and freshness signals

We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet. Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows. Job Description Position Summary The Senior IT Quality Engineering Specialist serves as the technical lead for the Kite Laboratory Information Management System (KLIMS) within North America West Coast (El Segundo). This role is responsible for the operational stability, compliance, maintenance, enhancement, and technical governance of the LabVantage platform and associated integrations. The position partners closely with Quality Control, Manufacturing, Validation, Infrastructure, and Kite Business stakeholders to ensure reliable and compliant laboratory operations. Key Responsibilities System Administration & Operational Support • Provide day-to-day administration and technical support for KLIMS and related

JavaSQLRecruitment
G
📍 California, Foster City, United States
✓ High-confidence listingCompany trend +5.2%

$243.1K – $314.6K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Oncology Business, Strategy, and Operations Lead will play a pivotal role in supporting the SVP of Oncology Clinical Development in building and executing the strategic vision for the Oncology Therapeutic Area (TA). As Gilead Oncology enters an exciting phase of growth and investment, this position offers the unique opportunity to collaborate directly with senior leadership to advance a world-class clinical development team, build the portfolio, and elevate oncology as a key focus area for Gilead. RESPONSIBILITIES As a member of the Oncology Leadership Team help to design and facilitate

RecruitmentHR
P
Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 New York, NY, United States
✓ Quality checkedCompany trend -86.4%

About Pinterest: Millions of people around the world come to our platform to find creative ideas, dream about new possibilities and plan for memories that will last a lifetime. At Pinterest, we’re on a mission to bring everyone the inspiration to create a life they love, and that starts with the people behind the product. Discover a career where you ignite innovation for millions, transform passion into growth opportunities, celebrate each other’s unique experiences and embrace the flexibility to do your best work. Creating a career you love? It’s Possible. At Pinterest, AI isn't just a feature, it's a powerful partner that augments our creativity and amplifies our impact, and we’re looking for candidates who are excited to be a part of that. To get a complete picture of your experience and abilities, we’ll explore your foundational skills and how you collaborate with AI. Through our interview process, what matters most is that you can always explain your approach, showing us not just what you know, but how you think. You can read more about our AI interview philosophy and how we use AI in our recruiting process here . Pinterest is building its programmatic and ad tech capabilities from the ground up to enhance the comprehensiveness and shoppability of ads. By expanding advertising demand sources through strategic partnerships with third-party platforms, agencies, and media companies, we are strengthening our performance marketing ecosystem. As Senior Manager of Programmatic Tech Operations, you will play a pivotal role in shaping the operational strategy, team, and roadmap behind a new and high-impact function. This is a rare opportunity to make a lasting impact on Pinterest’s global programmatic advertising solutions, influence ad products at scale, and drive innovation across one of the internet’s most engaged user communities. What you’ll do: Build and lead Pinterest’s Programmatic Tech Operations, shaping scalable processes, team structure, and best

Machine LearningAIExcelTableau
S
📍 Menlo Park, California, United States· Full-time
✓ Quality checkedCompany trend -93.3%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. At Snowflake, we empower both enterprises and individuals to reach their full potential. Our culture prioritizes impact, innovation, and collaboration, making Snowflake the ideal place to build ambitious projects, execute quickly, and advance technology — and your career — to the next level. The Role We are seeking a Senior Manager, Applied Field Engineering — AI/ML Product Specialists to lead a high-performing team of AI/ML specialists at the intersection of product, field, and customer success. In this hands-on leadership role, you will manage a team of Applied Field Engineers who are deep practitioners in Snowflake's AI/ML product portfolio — including Cortex AI, ML modeling, and agentic workflows. You will drive product adoption and customer outcomes, ensuring customers move beyond initial activation to unlock the full depth of Snowflake's AI/ML capabilities. Critically, you will serve as a strategic bridge between the field and Snowflake's product organization — translating customer experience into structured product insight that directly shapes roadmap priorities. You will work closely with Product Management, Engineering, and Sales leadership to ensure Snowflake builds the right things and customers realize their full potential. Responsibilities & Focus Areas Pro

AIGoRustMarketing

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