Jobs in United States

Lead Senior Staff Technical Program Manager 2c Site Reliability Engineering in United States

2,434 active opportunities · Updated October 2026

Explore current lead senior staff technical program manager 2c site reliability engineering jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

Hiring demand

35/100

watch · 21 related jobs

Hiring trend

-38.5%

Job postings compared with the previous 30 days

Remote options

14.3%

Share of matching jobs listed as remote

Typical salary

$127.5K – $127.5K/yr

Based on 6 salary observations

H
📍 Oregon, United States of America, United States
✓ High-confidence listingCompany trend +103.7%

$116.2K – $182.4K/yr

Quick readStrong listing-quality and freshness signals

PageWide Industrial Strategic Sourcing Lead Description - We are seeking a Strategic Sourcing & Contract Manufacturing Lead to define and advance the organization’s approach to managing contract manufacturers and critical suppliers. This role establishes supplier governance and commercial standards, leads complex sourcing and negotiation strategies, and provides senior oversight for supplier performance, operational readiness, risk, and continuous improvement. Serving as a functional leader and advisor, the position guides supplier relationship owners and cross-functional partners in making consistent, well-informed decisions that balance business requirements, supply continuity, and long-term supplier capability. The ideal candidate brings extensive strategic sourcing and contract manufacturing experience, strong commercial judgment, and the ability to influence senior stakeholders and improve organizational capability without relying on direct authority. Responsibilities Contract Manufacturing and Supplier Performance Define and lead the management model for contract manufacturers and critical suppliers, including governance, performance expectations, review cadence, escalation protocols, and continuous improvement priorities. Establish expectations for cost, quality, delivery, inventory, capacity, responsiveness, compliance, operational readiness, and business continuity. Guide supplier relationship owners in resolving complex commercial, operational, quality, and supply continuity issues. Lead supplier performance reviews and long-term improvement plans that deliver measurable business results. Partner with Operations, Engineering, Quality, Finance, and Program Management to align supplier capabilities and deliverables with business requirements. Provide senior recommendations on supplier select

FinanceSupply ChainProcurement
P
📍 Washington, United States
✓ High-confidence listingCompany trend +671.4%

$68.6K – $114.3K/yr

Quick readStrong listing-quality and freshness signals

What You Will Achieve A Senior Associate Scientist (R2) position is available in the Conjugation Process Development group of Bioprocess R&D in USA - WA - Bothell. We’re seeking a passionate and creative individual to join a dynamic team of scientists and engineers focused on developing robust, scalable, and high productivity conjugation processes for the manufacture of antibody-drug conjugates (ADCs) for early- and late-phase clinical programs. The work will also involve working with commercial and clinical production facilities to ensure accurate technology transfer and successful large-scale production. You may also be involved in cutting-edge technology development projects that seek to discover new innovations for ADC process development and/or manufacturing. How You Will Achieve It Design, plan, and execute milligram to gram-scale conjugation experiments in the development laboratory. Ensures timely, effective, and high-quality documentation in electronic laboratory notebooks and internal technical reports. Communicate results and findings to stakeholders on a regular basis; present data/strategy to colleagues and management in internal and external venues (technical meetings, project team meetings, and conferences, etc.) as appropriate. Assist in or lead the technology transfer of manufacturing processes to clinical and commercial manufacturing facilities. Provide support and troubleshoot during manufacturing campaigns as needed. Work collaboratively with colleagues both within the group and cross-functionally; contribute to maintaining and improving upon our safe, effective and efficient lab operations. Qualifications Must-Have BS/BA in Chemistry, Biochemistry, Chemical/Biochemical Engineering, or other related disciplines with 3-4 years of experience, or MS in the above fields with 0-2 years of experience.

AIRecruitment
C
📍 Jersey City New Jersey United States, United States
✓ High-confidence listingCompany trend +800%
Quick readStrong listing-quality and freshness signals

Citi, the leading global bank, has approximately 200 million customer accounts and does business in more than 160 countries and jurisdictions. Citi provides consumers, corporations, governments, and institutions with a broad range of financial products and services, including consumer banking and credit, corporate and investment banking, securities brokerage, transaction services, and wealth management. As a bank with a brain and a soul, Citi creates economic value that is systemically responsible and in our clients’ best interests. As a financial institution that touches every region of the world and every sector that shapes your daily life, our Enterprise Operations & Technology teams are charged with a mission that rivals any large tech company. Our technology solutions are the foundations of everything we do from keeping the bank safe, managing global resources, and providing the technical tools our workers need to be successful to designing our digital architecture and ensuring our platforms provide a first-class customer experience. We reimagine client and partner experiences to deliver excellence through secure, reliable, and efficient services. Our commitment to diversity includes a workforce that represents the clients we serve from all walks of life, backgrounds, and origins. We foster an environment where the best people want to work. We value and demand respect for others, promote individuals based on merit, and ensure opportunities for personal development are widely available to all. Ideal candidates are innovators with well-rounded backgrounds who bring their authentic selves to work and complement our culture of delivering results with pride. If you are a problem solver who seeks passion in your work, come join us. We’ll enable growth and progress together. Position Overview: The Senior Platform Engineering Lead is a pivotal senior-level engineering position responsible for driving the

JavaAngularSQLArtificial Intelligence
G
📍 California, United States
✓ High-confidence listingCompany trend +190.5%
Quick readStrong listing-quality and freshness signals

We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet. Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows. Job Description The Senior Manager, Kite Safety and Pharmacovigilance provides scientific and strategic leadership for pharmacovigilance activities supporting Kite’s investigational and marketed products. This role serves as a senior pharmacovigilance science expert, leading complex safety analyses, regulatory deliverables, and cross-functional safety strategy execution. Key Responsibilities Aggregate Reporting and Medical Writing Serve as lead author for complex aggregate safety reports, including PSURs, PBRERs, and DSURs, synthesizing global safety data and clinical context Author and review high-impact safety documents supporting regulatory submissions and lifecycle management Safety Analysis and Signal Management <

Recruitment
B
📍 New York, New York, United States
✓ High-confidence listing

$147K – $187K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Design at Brex Design at Brex creates the experiences that make complex systems feel effortless through thoughtful, scalable design. Whether crafting interfaces, shaping product strategy, or harnessing AI to empower our users, we obsess over quality and clarity. This is a team where creativity meets high craft — and where designers grow by building for ambitious customers. Our production and operations function is essential to making our designers succeed on this mission. What you’ll do We’re seeking an exceptional Senior Brand Producer to join as the first individual contributor on the Creative Operations team. You’ll set the high bar for this role and help define what great production looks like at Brex. This is a highly visible, hands-on role where you’ll lead the execution of complex creative projects from start to finish. You’ll bring both strategic oversight and tactical excellence — ensuring the right systems, vendors, and work

AIAccountingFinance
B
📍 Seal Beach, Canada
✓ High-confidence listingCompany trend +515.8%
Quick readStrong listing-quality and freshness signals

Configuration Management Specialist (Senior) Company: The Boeing Company Boeing Space, Intelligence & Weapons Systems (SI&WS) in Seal Beach California or Colorado Springs, Colorado, is seeking an Configuration Management Specialist (Senior) to support the ESS – MPA Phase 3 Program. Responsibilities of this position include but not limited to oversee and review of software and hardware documentation for internal consistency and adherence to Boeing and program standards, oversee configuration control of work products, generating CM records as evidence of adherence to CM plans and Boeing standards, verifies accuracy of deliveries, both internal and external, support Change Boards, and responds to internal audits and customer queries. This position requires the CM representative to lead the CM activities for the program and also be responsible for maintaining large number of documents. This position is expected to be 100% onsite in Seal Beach CA or Colorado Springs CO This position also requires the person to have an active DOD-Top Secret Clearance . Position Responsibilities: Oversee and review software and hardware documentation for internal consistency and adherence to Boeing and program standards. Oversee configuration control of work products. Generate CM records as evidence of adherence to CM plans and Boeing standards. Verify accuracy of deliverables, both internal and external. Support Change Boards. Respond to internal audits and customer queries. Lead CM activities for the program and maintain a large number of documents. This position is expected to be fully on site in Seal Beach, California or Colorado Springs, CO. <

Recruitment
H
📍 Texas, United States of America, United States
✓ High-confidence listingCompany trend +103.7%

$147.1K – $230.9K/yr

Quick readStrong listing-quality and freshness signals

Platform Deployment Management Lead Description - Job Summary • This role is responsible for leading the development and success of software products or features. The role formulates strategies and meticulous software plans for organization's platforms and technologies. The role recruits, motivates, mentors, coaches, develops, and retains a high-performing team of product managers and product marketers. Responsibilities • Plays a leadership role and drives the progress of the product management function. • Leads cross-functional teams through agile development processes, including sprint planning, daily stand-ups, and retrospectives. • Monitors competitive market to determine client needs for certain product improvements. • Strategically partners with key senior stakeholders to understand needs and priorities. • Recommends product requirements and definitions to align with stakeholder's needs. • Collaborates with the software engineering team on feature ideas and prototypes to bring potential solutions to life. • Advises key stakeholders on the portfolio strategy across all phases of the lifecycle. • Tracks and reports key metrics to drive future product developments. • Collaborates with marketing and sales teams to develop go-to-market strategies, product launch plans, and marketing collateral. • Demonstrates process improvement and project management experience, preferably with the implementation of large projects. Education & Experience Recommended • Four-year or Graduate Degree in Computer Science, Software Engineering, Information Systems, or any other related discipline or commensurate work experience or demonstrated competence. • Typically has 10&#43; years of work experience, preferably in product management, digital or software product development, or a related field.

Project Management
M
📍 California, United States of America, United States
✓ High-confidence listingCompany trend +1850%
Quick readStrong listing-quality and freshness signals

We anticipate the application window for this opening will close on - 10 Oct 2026 Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72&#43; million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact. A Day in the Life The Neuromodulation Research & Development organization develops therapies and technologies that address chronic pain and other neurological conditions. Within the Interventional Pain portfolio, teams focus on minimally invasive therapies used to treat musculoskeletal pathologies, including vertebral compression fractures, nerve pain, metastatic bone tumors, and benign bone tumors. This role supports the development of system-level verification and validation strategies for new products and enhancements across mechanical, electrical, and software components. This position is based in Santa Clara, California, and follows an onsite work model. No travel is required for this role. As a Research & Development Test Engineer, you will lead and execute verification and validation activities that support the development of interventional pain therapies and associated medical device systems. You will collaborate with cross-functional partners to define test strategies, evaluate product performance, manage technical risks, and generate evidence needed to support product development and regulatory requirements. Primary Responsibiliti

RecruitmentHR
M
📍 Colorado, United States of America, United States
✓ High-confidence listingCompany trend +1850%
Quick readStrong listing-quality and freshness signals

We anticipate the application window for this opening will close on - 2 Oct 2026 Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72&#43; million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact. A Day in the Life The Acute Care & Monitoring (ACM) Operating Unit develops technologies that help clinicians monitor, diagnose, and manage patients across care settings. Within ACM, the Product DNA organization is responsible for advancing product lifecycle processes, data governance, and digital capabilities that support efficient product development, commercialization, and ongoing lifecycle management. The team partners across research and development, quality, regulatory, operations, information technology, and business functions to drive standardized processes, enterprise system adoption, and operational excellence. This role may be based at the Medtronic campus in Lafayette, Colorado or the office in Mounds View, Minnesota. This is an onsite position that requires regular in-person collaboration with cross-functional stakeholders and project teams. Travel up to 25% is required to support program activities, stakeholder engagement, deployments, and collaboration across Medtronic locations. As Senior Program Manager, Business Transformation, you will lead strategic transformation initiatives like the PTC Windchill integration that improve how product information, business processes, and enterprise technologies support the product lifecycle. This role

SapRecruitmentHR
M
📍 O Fallon, Missouri, United States
✓ High-confidence listingCompany trend +212.5%
Quick readStrong listing-quality and freshness signals

Our Purpose Mastercard powers economies and empowers people in 200&#43; countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential. Title and Summary Senior Software Engineer Job Overview: Responsible for the analysis, design, development, testing, and delivery of secure, scalable software solutions. Define requirements for new applications and customization adhering to Mastercard standards, processes, and best practices. Develop, customize, and test applications to integrate to Mastercard specifications. Provide leadership, mentoring, and technical training to other team members. Major Accountabilities • Plan, design, architect, and develop secure, scalable, and maintainable technical solutions and alternatives to meet business requirements in adherence with Mastercard standards, processes, and best practices • Lead day-to-day system development and maintenance activities of the team to meet service level agreements (SLAs) and create solutions with a high level of innovation, cost effectiveness, quality, reliability, and faster time to market. • Accountable for the full systems development life cycle including creating high-quality requirements documents, use cases, designs, and other technical artifacts including but not limited to detailed test strategies, performance benchmarking, release rollout and deployment plans, contingency/back-out plans, feasibility studies, cost and time analysis, and detailed estimates. • Design, develop, test, dep

JavaDockerGitAI
M
📍 O Fallon, Missouri, United States
✓ High-confidence listingCompany trend +212.5%
Quick readStrong listing-quality and freshness signals

Our Purpose Mastercard powers economies and empowers people in 200&#43; countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential. Title and Summary Senior Technical Program Manager Overview As a Senior Technical Program Manager at Mastercard, you’ll bring your expertise with conceptualizing, coordinating and driving technology projects, and coaching Agile practices in high-performing, self-organizing development teams. We’re building a global B2B, microservices-based platform to help businesses of all sizes streamline how they manage payments when buying or selling products & services. As a global business, the projects you lead for Mastercard will deliver software operating at massive scale requiring a focus on performance, security, and reliability. This role will support our Network Solutions team within Payment Networks, assisting the development team with building out software solutions for Mastercard. Role: • Dive as deep as you want into the tech stack, the integration patterns, the organizational capabilities, and the company wide assets that can be leveraged to provide technical solutions to customer problems. • Contribute to the strategies, design choices, and even the cloud infrastructure necessary to build comprehensive and achievable execution plans to deliver high-profile new features and capabilities for our customers. • Drive the execution of an initiative that may span multiple teams and integrations, reporting meani

AIRecruitment
A
📍 Denver, CO, United States
✓ High-confidence listingCompany trend +90.9%
Quick readStrong listing-quality and freshness signals

Job Requisition ID # 26WD101306 Position overview Autodesk Flow is the connected platform behind how film and television get made — from the moment footage is captured on set, through review and approval, to final delivery. This is a dedicated ABM role for Flow, working hand in hand with the Flow sales organization. You will be their marketing counterpart: building the account clusters, programs and sales-facing materials that turn business priorities into engaged accounts and qualified pipeline. You will shape how the account-based motion works here — how accounts are scored and clustered, how programs are built around sales priorities, and how we measure what they produced. You will work in close partnership with a Field Marketing Manager, the wider Media & Entertainment marketing organization, and our central content team. Location :This position can be remote or hybrid. Responsibilities Partner with Sales: Act as the dedicated ABM partner to the Flow sales organization, building programs around their account priorities and revenue targets Run a recurring planning cadence with Sales — account co-planning, pipeline reviews and quarterly business reviews — reviewing engagement, buying signals and next best actions Own lead routing and funnel optimization for Flow, making sure the handoff from marketing program to seller follow-up is fast, clean and measured Partner across Marketing, Industry Strategy and Technical Sales to coordinate account engagement Build and prioritize account clusters: Build account clusters around shared buying t

AISalesforceCRM
S
📍 New York City, New York, United States· Full-time· Remote
✓ High-confidence listingCompany trend -81%
Quick readStrong listing-quality and freshness signals

Synthesia is the world’s leading AI video platform for business, used by over 90% of the Fortune 100. Founded in 2017, the company is headquartered in London, with offices and teams across Europe and the US. As AI continues to shape the way we live and work, Synthesia develops products to enhance visual communication and enterprise skill development, helping people work better and stay at the center of successful organizations. Following our recent Series E funding round, where we raised $200 million, our valuation stands at $4 billion. Our total funding exceeds $530 million from premier investors including Accel, NVentures (Nvidia's VC arm), Kleiner Perkins, GV, and Evantic Capital, alongside the founders and operators of Stripe, Datadog, Miro, and Webflow. About the Role Synthesia is looking for a Senior Sales Operations Analyst to help our sales organization run efficiently, scale smoothly, and make faster, better-informed decisions. You'll own the systems, data, and processes that power our go-to-market motion partnering closely with Sales, Finance, and RevOps to keep the engine running and to surface the insights leadership needs to forecast and plan. This is a hands-on role for someone who's equally comfortable deep in Salesforce configuration as they are building a forecast model or presenting a pipeline analysis to sales leadership. What You'll Do Drive reporting & analytics — Build and maintain dashboards for pipeline, forecast, quota attainment, and funnel conversion; deliver regular reporting to sales leadership Support forecasting — Prepare and validate the data behind weekly/monthly/quarterly forecast calls Design sales processes — Improve territory planning, lead routing, deal desk operations, and quote-to-cash workflows Support compensation & quota planning — Model commission plans, calculate payouts, and assist with quota-setting analysis alongside Finance Partner cross-functionally — Work with Marketing, Customer Success/RevOps, and Finance

SQLAISalesforceExcel
G
📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$169.3K – $219.1K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description At Gilead our pursuit of a healthier world for all people has yielded a cure for hepatitis C, revolutionary improvements in HIV treatment and prevention as well as advancements in therapies for viral and inflammatory diseases and certain cancers. We set and achieve bold ambitions in our fight against the world’s most devastating diseases, united in our commitment to confronting the largest public health challenges of our day and improving the lives of patients for generations to come. The Protein Therapeutics department is seeking a highly motivated laboratory-based scientist to lead the Molecular Biology function within the Mammalian Expression team. In this capacity

PythonExcelRecruitment
S
📍 California, Fremont 47900 Bayside Pkwy, United States· Hybrid
✓ High-confidence listingCompany trend +364.7%
Quick readStrong listing-quality and freshness signals

Work Flexibility: Hybrid or Onsite Stryker is hiring a Senior Quality Engineer to join our Neurovascular division. This is a hybrid r ole based in Fremont, CA or Salt Lake City, UT . As the Senior Design Quality Engineer , you will be actively involved in Product Risk Management, Post Market Surveillance, Design Control and Product Quality Improvement. You will be involved in a fast-paced mix of short design change efforts and will be responsible for product risk management and adherence to design control requirements throughout the product lifecycle. You will be responsible for ensuring that post market data and feedback is channeled into the risk management system throughout the product lifecycle. You will make regular use of problem-solving tools and statistical analysis to analyze and trend data and provide quality input into technical investigations, perform test method development and validation, design verification, risk assessment and design reviews. You will be responsible for supporting product testing and failure analysis, writing protocols and reports, creating and maintaining risk files and assessing the impact of necessary changes to our products. You will lead initiatives to increase sales and improve the customer experience of our devices. Neurovascular (NV) products push the boundaries of technology to meet ever increasing product performance requirements, making the goal of assessing and demonstrating, safety, performance and compliance an exciting challenge. What You Will Do Develop qualification plans, protocols, and reports for new products, existing products, components, and subassemblies. Execute product testing, inspection, verification, and validation activities to support design and quality objectives. Perform failure investigations and root cause anal

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