About the Team Security is at the foundation of OpenAI’s mission to ensure that artificial general intelligence benefits all of humanity. The Security team protects OpenAI’s technology, people, and products. We are technical in what we build but are operational in how we do our work, and are committed to supporting all products and research at OpenAI. Our Security team tenets include: prioritizing for impact, enabling researchers, preparing for future transformative technologies, and engaging a robust security culture. About the Role OpenAI is seeking a Principal Security Engineer to join our Infrastructure Security (InfraSec) team. InfraSec protects the foundations of OpenAI’s research and production environments, spanning GPU supercomputing clusters, multi-cloud infrastructure, datacenters, networking, storage, and the critical services that power our frontier AI models. Our charter includes securing everything from bare-metal hardware and firmware, to Kubernetes clusters and service meshes, to data storage and access pathways for highly sensitive model weights and user data. As a principal engineer, you will set technical direction and drive execution on high-impact infrastructure security programs, partnering across various orgs at OpenAI to deliver durable controls that raise the security bar at OpenAI scale. In this role, you will: Own end-to-end security outcomes for one or more critical infrastructure areas, including multi-quarter strategy, roadmap, and delivery. Design and build security controls across diverse layers (e.g., physical hardware, firmware/BMC, OS, Kubernetes, networks, and CI/CD) to defend against sophisticated adversaries and insider threats. Lead cross-functional programs to deploy security enhancements and control changes across broad-scale infrastructure, balancing security guarantees with reliability and velocity. Take a generalist approach to building security controls, balancing a mix of security expertise and broad technical skillsets
Jobs in United States
Lead Technical Program Manager 2c Knowledge Systems in United States
2,434 active opportunities · Updated October 2026
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Explore current lead technical program manager 2c knowledge systems jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.
From $295.3K/yr
Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. As a Principal Software Engineer on the Sharing team, you will lead large, multi-team initiatives with long-term technical vision and group-level impact. You will be expected to define and drive the platform-wide strategy powering how millions of users capture, share, and discover content on Roblox. In this role, you will set engineering standards, mentor senior engineers, and serve as a key architect of our long-term technical direction. You Will Drive Strategy & Execution: Own the outcome of complex, business-critical programs spanning several teams, often lasting years. Innovate at Scale: Develop and drive a multi-year technical vision for content creation and sharing, anticipating scale, technology, and business evolution. Elevate Reliability: Lead high-severity incident response across groups; drive durable systemic solutions that improve reliability and velocity. Architect Foundations: Regularly improve shared infrastructure and foundational systems, introducing frameworks that uplift development speed across the organization. Align Teams: Aligns multiple teams on shared technical direction, producing detailed design docs, phased roadmaps, and planning models that balance short an
About the Team OpenAI, in close collaboration with our capital partners, is building the world’s most advanced AI infrastructure ecosystem. Our Industrial Compute organization develops and deploys large-scale AI campuses designed to support the next generation of frontier model training and inference workloads. The Hardware Operations team is responsible for ensuring the reliability, availability, and lifecycle health of OpenAI’s compute infrastructure. We partner closely with Data Center Operations, Fleet Health Engineering, Manufacturing, Network Infrastructure, Capacity Planning, and our infrastructure partners to maintain world-class operational performance across rapidly expanding AI environments. As we scale globally, we are building the operational frameworks, reliability standards, and sustaining engineering practices required to support thousands of GPUs and servers across multiple campuses. About the Role We are seeking a Datacenter Hardware Technician Lead to serve as the senior on-site technical authority for hardware reliability and fleet health at one of OpenAI’s flagship AI campuses. This role operates at the intersection of hardware operations, sustaining engineering, and fleet reliability. You will partner closely with Cloud Service Provider operations teams, OpenAI fleet-health engineers, hardware engineering teams, and OEM vendors to identify, diagnose, and resolve hardware issues affecting production systems. Beyond day-to-day operational support, you will drive root cause investigations, reliability improvement initiatives, lifecycle management programs, and operational readiness efforts. You will help establish hardware maintenance standards, operational procedures, and best practices that scale across future OpenAI infrastructure deployments. The ideal candidate combines deep hands-on datacenter hardware expertise with strong troubleshooting, failure analysis, and cross-functional leadership skills. Candidates must be able to sit onsite at our
$169.3K – $219.1K/yr
At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Senior Scientist, Purification Process Development (Pivotal & Commercial) role will be responsible for leading aspects of purification development including commercial process development and process characterization for multiple biologics programs during pivotal phases (phases II/III and post-launch). In addition, this role is also expected to lead/support technology transfer, participate in purification and cross-functional initiatives, and support purification regulatory documentation. Key Responsibilities: Design experiments and demonstrate hands-on technical leadership of all aspects of purification process development including chromatography, TFF, virus f
Mission Systems Engineers (Associate or Experienced) Company: The Boeing Company Boeing Defense Space & Security (BDS) has an exciting opportunity for Mission Systems Engineers (Associate or Experienced) to join our Experimental Systems Group (ESG) located in Seal Beach, CA; with options to work from Aurora, CO or El Segundo, CA ; to support development of new first-of-kind space vehicles and missions. ESG supports a variety of government customers spanning technology domains, and is an extremely fast-paced, responsive development environment delivering new capabilities to customers rapidly and affordably. The ESG portfolio consists of a range of platforms and technologies including the X-37B, the world’s first fully autonomous reusable spaceplane, which is continuing to shape the future of space technology while flying its eighth mission. As a mission systems engineer, you will be expected to lead modelling and simulation efforts and enable your assigned programs’ development from early capabilities studies through demonstration. You will serve as a core point of contact for customers and will work directly with subject matter experts across the business to quickly iterate and converge on achievable solutions that meet our customers’ needs. Our development timelines are aggressive, and you will be asked to develop solutions to previously unsolved problems. In this role, you will work in multidisciplinary teams to bring concept of operations to fruition in support of our customers’ mission objectives. You will work both as an individual contributor and as a product lead. An ideal candidate has a strong technical background across all spacecraft subsystems with particular depth in Attitude Control Systems (ACS)/Guidance Navigat
We believe that the way people interact with their finances will drastically improve in the next few years. We’re dedicated to empowering this transformation by building the tools and experiences that thousands of developers use to create their own products. Plaid powers the tools millions of people rely on to live a healthier financial life. We work with thousands of companies like Venmo, SoFi, several of the Fortune 500, and many of the largest banks to make it easy for people to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Washington D.C., London and Amsterdam. The Customer Operations team sits at the center of how we scale world-class customer experiences at Plaid. As the Customer Operations Leader, you'll own the strategy and execution of all global ops initiatives in a director level role — leading a team across product operations, customer experience engineering, technical enablement, and org development. As Customer Operations Leader, you'll focus on scaling operations and enablement across the full customer lifecycle for our Customer Engineering organization, including Support, Technical Account Management, Sales Engineering and Professional Services. You'll be responsible for building our VoC programs as a strategic lever to drive insights from our frontline teams into product improvements and adoption strategies. You will build tooling and programs with measurable outcomes that remove friction for customers and empower our customers to serve themselves. Responsibilities Hire, develop, and lead a high-performing Customer Ops team across Product Operations, Customer Experience Engineering and Technical Enablement Own operations strategy and execution across the full customer lifecycle for Support, Technical Account Management, Sales Engineering and P
At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. At Snowflake, we are building a high-impact team to help the world's most innovative companies unlock the power of AI. As a Senior Forward Deployed Engineer, Applied AI on our Cortex AI team, you will be a hands-on technical leader and trusted partner to our most strategic customers. You will own the end-to-end delivery of enterprise AI programs, leading a team of 2–4 engineers while staying deeply technical yourself. You will set the technical direction for your customer engagements, mentor your team, and serve as the senior technical voice at the intersection of product, engineering, and customer success. IN THIS ROLE AT SNOWFLAKE, YOU WILL: Lead Customer Programs : Own the full lifecycle of complex, multi-engineer AI engagements – from scoping and architecture through deployment, monitoring, and handoff. Be accountable for delivery quality and customer outcomes for the projects you lead. Own AI Quality : Define what "good" means for each engagement. Translate ambiguous customer goals into measurable quality metrics, evaluation frameworks, and golden datasets – then run systematic eval loops to hill-climb on agent quality, catch regressions before customers do, and continuously raise the bar on accuracy, faithfulness, and safety. Set the standard for how the team measures
$185K – $220K/yr
Who We Are Notion is the collaborative AI workspace where teams and agents think together . We're building one place where your knowledge, projects, meetings, and AI tools live side by side, so work is faster, clearer, and less fragmented. Millions of individuals, small teams, and large companies run their work on Notion. Notinos (our employees) are customer zero in bringing this future of work to life. We care about craft, building things that last, and the belief that great work is still fundamentally human. Our goal isn’t to ship the next feature. Each and every team of Notinos is working to set the standard for how humans work together in the AI era. From building a business’s system of record to making and managing AI agents to automating away the busy work, we care deeply about giving our customers more time for their life’s work. About the Role: We are seeking a strategic and technically fluent Lead, IT Audit to join our Finance team reporting to the Head of Internal Audit. This is a broad, high-impact role spanning both IT SOX compliance and operational IT audits. You will help establish and elevate our technology controls program end to end — owning the IT SOX lifecycle, designing the IT general and application controls framework, embedding AI and automation into how we test and monitor controls, and delivering value-added operational IT and cybersecurity audits that strengthen how the company builds and runs its systems. You will partner with leaders across Engineering, Security, IT, Finance, and the business to ensure sound technology controls are built into how the company operates as we scale. This role is ideal for someone who thinks like a builder, not just an auditor — someone who can translate complex control and security requirements into practical, scalable processes in a fast-moving SaaS environment with modern cloud architecture and complex data flows. This role can be based in either San Francisco or New York City. We work from our offices on M
About Sentry Software runs the world and the pace is faster than ever. Sentry helps developers fix errors and performance issues before users notice, so teams can spend less time firefighting and more time building. Trusted by 200,000+ organizations, Sentry is today’s application monitoring standard and our team is building its AI-native future. About the Role Sentry's blog, newsletter, and content programs need an owner — someone who can walk into ambiguity, decide what needs to exist, and just start making it happen. This is a self-starter role in the truest sense: no one is handing you a content calendar and asking you to fill it in, you're the one building the calendar. You should be quick with a draft and quicker to ship it — bias to action over polished process. You're technically savvy enough to keep up with a developer audience and write about our product credibly (or make an exec sound like they wrote it themselves). And you're proactive: you see the narrative before anyone asks you to go find it. You'll work collaboratively with Growth, Comms, PMM, and DevEx, with real ownership and editorial judgment to know what's worth writing and what isn't. In this role you will Co-lead blog strategy. Partner closely with Growth to run the editorial calendar, and scale the program by focusing on creating thought leadership, customer and employer brand content to create a robust narrative driven editorial program in collaboration with comms, devex and product marketing. Oversee the quality itself. Be the last line of defense on quality and prose — every post should read like it came from the same sharp, confident voice. Track the industry and get us into the conversation. Know what's trending in the developer and infrastructure world before it's obvious, and turn that into content that puts Sentry in the room. Collaborate with Comms and Marketing to push those narratives forward. Content partner for the exec team. Collaborate closely with core execs to support content
From $160K/yr
Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: The Growth Marketing team sits at the intersection of marketing, data, and technology, driving scalable acquisition and measurable business impact across Airbnb. Our work is critical to driving the company’s top line growth. We are looking for a highly strategic and technically savvy Growth Marketing Lead to own Host SEM, the supply side of our Paid Search program. You will be a channel expert, thought partner, and trusted advisor to leaders and business partners across Product, Data Science, Engineering, Supply, FP&A, Brand, and Creative teams to shape strategy and exceed ambitious KPI goals. The Difference You Will Make: You will lead end-to-end strategy and execution of Airbnb's Global Host SEM program, driving efficient host acquisition and long-term supply growth. You'll lead large-scale SEM investments across major search platforms, identify new growth opportunities, design and scale experimentation to inform investment decisions, and optimize performance to maximize business impact and ROI. You’ll collaborate cross-functionally to drive scalable solutions, influence roadmaps, and communicate data-driven recommendations to senior leadership that shape key business decisions. A Typical Day: Lead Airbnb's global Host SEM program across major search platforms (Google, Bing, and emerging channels) to drive efficient host acquisition and long-term supply growth. Develop and execute the strategic roadmap for Host SEM, aligning investment strategy and budget allocation with global and regional business priorities. Design, execute, and scale experiments across bi
From $170K/yr
Datadog is seeking a highly motivated Senior Corporate Development Lead to drive our AI product strategy, build strong relationships across the founder and VC ecosystem, and support high-impact initiatives including acquisitions, venture investments, and startup partnerships. You will be part of a small, high-visibility team that reports directly to Datadog's Founder/CEO. The ideal candidate is passionate about AI and developer tools, comfortable rolling up their sleeves, and excited to operate in a fluid, technically demanding environment. You will support evaluations, source promising AI startups, collaborate closely with internal product and engineering leaders, and help position Datadog as the preferred partner for the next generation of founders. This role is ideal for someone who is hungry for increased responsibility, operates with authenticity and creativity, and prioritizes the company's interests. At Datadog, we place value in our office culture - the relationships and collaboration it builds, and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You'll Do: Support Datadog's AI product strategy by analyzing emerging technologies, market opportunities, and competitive dynamics. Source high-potential AI startups for acquisition, investment, or partnership, and build a strong presence across the founder and VC ecosystem through meetups, conferences, and events. Drive workstreams across diligence, valuation, financial modeling, strategic assessment, and internal recommendations. Partner with Product and Engineering leaders to evaluate build/buy/partner opportunities aligned with Datadog's AI roadmap. Support negotiation processes, including term sheets and partnership structures, and collaborate on integration planning with cross-functional partners after deals close. Help attract early-stage AI companies into Datadog's startup program. Wh
From $180K/yr
We are a global team of innovators and pioneers dedicated to shaping the future of observability. At New Relic, we build an intelligent platform that empowers companies to thrive in an AI-first world by giving them unparalleled insight into their complex systems. As we continue to expand our global footprint, we're looking for passionate people to join our mission. If you're ready to help the world's best companies optimize their digital applications, we invite you to explore a career with us! Your opportunity New Relic is looking for a strategic, technically fluent Competitive Intelligence (CI) Director to own our competitive intelligence program from strategy through execution. In this strategic role, you will be the company’s foremost expert on the observability, monitoring, and AIOps competitive landscape tracking and analyzing New Relic competitors and turning that analysis into intelligence that sharpens our positioning, accelerates win rates, and informs product and GTM strategy. This is a role for a proven CI leader who can operate at the intersection of technology and go-to-market. Ideally someone equally comfortable digging into distributed tracing or AIOps and AI observability capabilities with product teams as briefing the field or executive staff on what it means for New Relic’s competitive position. If you thrive on staying ahead of a fast-moving observability market and building the programs, content, and platform that keep an entire GTM organization sharp, we want to hear from you. What you'll do Own and Scale the CI Program: Lead New Relic’s global competitive intelligence program end-to-end competitor tracking, battlecards, and competitive playbooks, plus the CI platform that powers enablement across Sales, Marketing, and Product. Build the Competitive Knowledge Base: Develop and maintain in-depth, technically accurate coverage of key observability, monitoring, and AIOps competitors. This includes product architecture, pricing, roadmap signal
At Vanta, our mission is to help businesses earn and prove trust. We believe that security should be monitored and verified continuously, and we empower companies to practice better security and prove it with ease. Vanta has a kind and talented team, and while some have prior security experience, many have been successful at Vanta without it. Vanta for Government (V4G) is how we bring that mission to the public sector. As federal compliance undergoes its biggest shift in a decade — FedRAMP 20x, machine-readable authorization, OSCAL — we're building the platform that turns federal frameworks into automated, continuously monitored product experiences. The GRC Subject Matter Experts on this team are the people who make that possible. As Vanta's GRC Subject Matter Expert for V4G , you'll own federal compliance content used by every customer pursuing or maintaining federal authorization on our platform. This is an interpretation-and-authoring role, not a compliance program administration role: your job is to interpret underlying control requirements, identify where FedRAMP modifies or constrains the NIST framework, and translate those interpretations into precise, technically testable guidance that engineering can build and customers can act on. The content you write ships as product — a five-person startup and a Fortune 100 CSP both receive it — so calibrating depth, precision, and universality is the core craft. You'll join Vanta's Security organization, which directly influences product development, facilitates the creation of automated GRC solutions for customers, and provides expert advisory services across the company. What you’ll do as a V4G GRC SME at Vanta: Build and own federal compliance frameworks — Lead the creation, enhancement, and lifecycle management of controls, evidence requirements, and implementation guidance for FedRAMP (Low/Moderate/High), NIST SP 800-53, NIST SP 800-171, CMMC, DFARS, and StateRAMP. Author clear control rationales, acceptance crite
Leidos has an exciting opportunity for a Lead Technical Project Manager (TPM) in our Enterprise Science Business Area specifically supporting our NASA customer. At Leidos, we offer competitive benefits, including Paid Time Off, 11 paid Holidays, Immediate Vesting in our 401K, Flexible Schedules, Discounted Stock Purchase Plans, Technical Upskilling, Education and Training Support, Parental Paid Leave, and much more. Join us and make a difference in NASA’s Mission! The Lead Technical Project Manager leads complex technical initiatives while also overseeing and guiding a team of Project Managers to ensure successful planning, coordination, and execution. This is a working Lead position, responsible for directly managing complex technical projects while also optimizing team performance, developing the technical capabilities of the TPM team, resolving cross-project challenges, managing resources, and maintaining consistent delivery standards across all efforts. PRIMARY RESPONSIBILITIES: Lead technical planning, architecture alignment, schedule management, and execution across one or multiple NASA projects. Ensure project activities integrate engineering constraints, system lifecycles, technical readiness, and solution architecture. Identify and diagnose technical blockers, working directly with engineering and technical SMEs to enable faster issue resolution and to reduce schedule delays. Understand and challenge technical decisions and workflows rather than simply relaying them administratively. <sp
About the Team OpenAI Finance is responsible for ensuring the organization is set up for success in pursuit of its mission. The Technical Accounting team plays a crucial role in helping OpenAI navigate complex, judgmental, and rapidly evolving accounting matters with rigor and clarity. We aim to bring both technical excellence and strong business partnership to some of the most novel accounting questions in the industry. About the Role As Senior Manager, Technical Accounting, Compute Infrastructure, you will lead the evaluation, documentation, and operationalization of complex accounting matters related to OpenAI's compute infrastructure, strategic investments, and other non-routine business activities.. This role sits at the intersection of U.S. GAAP technical accounting, infrastructure strategy, financial reporting, controls, and cross-functional execution. Key areas may include cloud compute arrangements, data center and colocation arrangements, lease accounting under ASC 842, power purchase agreements, strategic investments, consolidation evaluations under ASC 810, financial instruments, and other emerging or non-standard arrangements. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Lead technical accounting analysis for complex, judgmental, and non-routine transactions under U.S. GAAP. Evaluate accounting implications for compute infrastructure arrangements, including cloud compute, data center, colocation, lease, PPA, infrastructure procurement, and related commercial arrangements. Partner with Controllership, Tax, Legal, FP&A, Procurement, Infrastructure, and other cross-functional teams to assess the accounting implications of new products, commercial arrangements, strategic transactions, and business initiatives. Prepare and review technical accounting memoranda, position papers, and other auditor-ready documentation. Translate
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