Jobs in United States

Mission Systems Engineers in United States

2,141 active opportunities · Updated October 2026

Explore current mission systems engineers jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

G
📍 Field, United States
✓ Quality checkedCompany trend +190.5%

$133.2K – $172.4K/yr

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description As a Sr. Therapeutic Specialist within Gilead's HIV Treatment team, you will represent Gilead's products and services to a defined customer base. Your focus will be on generating and growing sales by consistently achieving or exceeding sales targets within a specific geographic area. This role emphasizes a comprehensive account management approach, engaging healthcare practices through in-person representation, face-to-face meetings, and strategic partnerships. You will establish strong working relationships with healthcare providers and deliver timely disease awareness information, clinical updates, and education on healthcare changes. The ability to distill complex clin

Recruitment
G
📍 California, United States
✓ Quality checkedCompany trend +190.5%

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Real-World Evidence (RWE) function at Gilead is part of the Clinical Data Sciences (CDS) group within the Clinical Development organization and aims to unlock the power of Real-World Data (RWD) to help transform innovations to life-changing medicines for patients. We are seeking a Senior Director, RWE Inflammation Product Lead who will be accountable for the development and execution of the RWE strategy in support of one or more Inflammation products under development. The incumbent will serve as the key RWE subject matter expert within Gilead's lifecycle management teams for the product(s) and all its indications across the development lifecycle and serve as a strategic

Recruitment
G
📍 California, United States
✓ Quality checkedCompany trend +190.5%

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description As the primary Public Affairs liaison to the R&D organization, the V ice P resident will develop and execute an integrated internal and external communications strategy that advances enterprise priorities, strengthens trust in our science, and enables business readiness for key pipeline and regulatory events. This leader will provide senior counsel to R&D and enterprise leaders on reputation and risk, set the operating model and governance for R&D communications globally, and build a high-performing team with deep scientific, regulatory, and issues-management expert

FinanceRecruitment
G
📍 New Jersey, United States
✓ Quality checkedCompany trend +190.5%

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description We are seeking a Clinical Data Scientist -RWE Data Analysis Oversight Lead: Inflammation. This position is responsible for the oversight of timeliness and quality of analysis results supporting the CDS-RWE book of work for the Inflammation therapeutic area (TA). This role reports to the CDS-RWE TA Head and supports the scientific leads in implementing strategies to generate analysis results that deliver on portfolio priorities. Serving as the primary point of contact for study and analysis vendors and service vendors, this role is responsible for planning, execution, and quality acceptance of analysis deliverables. The position requires demonstrated experience in managing complex analytical w

Recruitment
G
📍 California, United States
✓ Quality checkedCompany trend +190.5%

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description This will be a site base role at our global headquarters in Foster City, CA or our facility in Parsippany, NJ. We do offer a hybrid environment with three core collaboration days in the office (Tues-Thurs) and optional work from home days on Monday and Friday. Key Responsibilities Reporting to the Senior Director, Global Value and Access liver, inflammation, and emerging viruses (LIVE), GHEOR the Director role will: Lead the development and implementation of global HEOR strategies and programs for to support key marketed LIVE products and treatment pipeline by being a strategic cross-functional partner. Advocate and demonstrate subject matter expertise to sup

Recruitment
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📍 O Fallon, Missouri, United States
✓ Quality checkedCompany trend +212.5%

Our Purpose Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential. Title and Summary Director, Platform Engineering Who is Mastercard? Mastercard is a global technology company in the payments industry. Our mission is to connect and power an inclusive, digital economy that benefits everyone, everywhere by making transactions safe, simple, smart, and accessible. Using secure data and networks, partnerships, and passion, our innovations and solutions help individuals, financial institutions, governments, and businesses realize their greatest potential. Our decency quotient, or DQ, drives our culture and everything we do inside and outside of our company. With connections across more than 210 countries and territories, we are building a sustainable world that unlocks priceless possibilities for all. Role Summary Director, Platform Engineering At Mastercard, the pace of change across technology, AI, and the nature of work requires that we constantly push the boundaries for the technologies in building and operating infrastructure and applications globally. The Director, Platform Engineering is a critical technology and engineering leadership role within Operations Automation Program accountable for advancing our infrastructure and platform automation strategy through innovation and effective problem-solving. This role focuses on analyzing, coding, and delivering software an

PythonAWSAzureGCP
M
📍 O Fallon, Missouri, United States
✓ Quality checkedCompany trend +212.5%

Our Purpose Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential. Title and Summary Software Engineer II Overview Who is Mastercard? Mastercard is a global technology company in the payments industry. Our mission is to connect and power an inclusive, digital economy that benefits everyone, everywhere by making transactions safe, simple, smart, and accessible. Using secure data and networks, partnerships and passion, our innovations and solutions help individuals, financial institutions, governments, and businesses realize their greatest potential. Our decency quotient, or DQ, drives our culture and everything we do inside and outside of our company. With connections across more than 210 countries and territories, we are building a sustainable world that unlocks priceless possibilities for all. The Fraud Products team (part of O&T) is developing new capabilities for MasterCard's Decision Management Platform, which serves as the core for multiple business solutions to combat fraud and validate cardholder identity. Our patented Java-based platform processes billions of transactions per month in tens of milliseconds using a multi-tiered, message-oriented approach for high performance and availability. MasterCard software engineering teams leverage Agile development principles, advanced development, design and test automation practices, and an obsession over security, reliability, and perfo

JavaSQLJenkinsRecruitment
M
📍 New York City, New York, United States
✓ Quality checkedCompany trend +212.5%

Our Purpose Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential. Title and Summary Executive Assistant Who is Mastercard? Mastercard is a global technology company in the payments industry. Our mission is to connect and power an inclusive, digital economy that benefits everyone, everywhere by making transactions safe, simple, smart, and accessible. Using secure data and networks, partnerships, and passion, our innovations and solutions help individuals, financial institutions, governments, and businesses realize their greatest potential. Our decency quotient, or DQ, drives our culture and everything we do inside and outside of our company. With connections across more than 210 countries and territories, we are building a sustainable world that unlocks priceless possibilities for all. Overview: Mastercard Software Builders Experience (MSBX) is responsible for enabling more than 12,000 engineers globally to build, test, secure, and deliver software at scale. As part of Mastercard's ONE organization, MSBX delivers the platforms, tools, and services that power engineering productivity and developer experience across the enterprise. Our teams build and operate strategic capabilities including: • Developer Workbench and AI-powered engineering tools • Application frameworks and software bootstrapping services • Standardized CI/CD pipelines and developer tooling • Cloud platfo

AIExcelSupply ChainLogistics
O
📍 Chicago, Illinois, United States
✓ Quality checkedCompany trend +66.7%

Secure Every Identity, from AI to Human Identity is the key to unlocking the potential of AI. Okta secures AI by building the trusted, neutral infrastructure that enables organizations to safely embrace this new era. This work requires a relentless drive to solve complex challenges with real-world stakes. We are looking for builders and owners who operate with speed and urgency and execute with excellence. This is an opportunity to do career-defining work. We're all in on this mission. If you are too, let's talk. The Customer First Team We are a team of Identity and Access Management experts. We help customers, businesses, and organisations maximise their Okta IAM platform investment, providing rapid time-to-value in adoption and usage and promoting scalability and agility. Our team sits within the Customer First area - focused on ensuring the long term success of our customers. Join our team! We’re building a world where Identity belongs to you. Role Summary The Business Analyst (BA) is an essential member of the Okta Professional Services team. This role offers a unique opportunity to learn Identity and Access Management (IAM) fundamentals from the ground up. You will serve as a bridge between customer business objectives and technical implementation, developing the skills to own the requirements lifecycle and ensuring final deliveries are secure, scalable, and aligned with strategic needs. Key Responsibilities Discovery & Requirements Facilitation: Facilitate stakeholder workshops to uncover requirements, map current-state IAM processes, and identify dependencies and pain points across IT, security, and application teams. Documentation & Solution Design: Translate business needs into detailed functional and non-functional requirements. Produce clear business process flows and solution design diagrams to visualize the "how" and "why" behind the technical configuration. Traceability & Solution Integrity: Support senior team members in maintaining

Machine LearningArtificial IntelligenceAIRecruitment
S
📍 New York, NY, United States
✓ Quality checkedCompany trend -94.3%

Who we are About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies—from the world's largest enterprises to the most ambitious startups—use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone's reach while doing the most important work of your career. About the team This role is open to remote candidates located anywhere within the Eastern Time Zone. The Cash Platform team is part of Stripe's Money Movement Services Platform. We manage Stripe's FX and cash positions across the globe, owning two of the most commercially critical problems in our business: delivering the best possible FX trades for our users, and optimizing the cost and routing of cross-border payouts across countries. Stripe recently launched its own in-house bank, enabling near-instant movement of funds across accounts worldwide—and Cash Platform is at the center of bringing that infrastructure to Stripe's products and, increasingly, to our customers. What you'll do You'll work closely with engineering teams across Cash Platform and Money Movement Services, cross-functional partners spanning Legal, Treasury, Financial Crimes, and Sales, and senior stakeholders inside and outside Stripe. You'll define the strategy and roadmap for Stripe's FX and cross-border payout products, drive cost optimization and routing decisions at scale, and help shape the path toward monetizing Stripe's in-house banking infrastructure for users globally. Responsibilities You are expected to: Deeply understand the competitive landscape and define clear benchmarks for where Stripe's FX and cross-border payout products need to be Own the product strategy and roadmap for Cash Platform, balancing near-term cost and performance optimization with longer-term platform m

S
📍 New York, NY, United States
✓ Quality checkedCompany trend -94.3%

Who we are About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies—from the world’s largest enterprises to the most ambitious startups—use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone’s reach while doing the most important work of your career. What you’ll do As an Account Executive, Existing Business, you’ll be managing existing relationships and identifying new opportunities to expand Stripe’s footprint within existing accounts. Specifically, we’re looking for someone who can execute on long-term sales strategies, engage with internal and external stakeholders, align on technical and business requirements with product teams, build value in competitive situations, lead commercial negotiations, and close deals. Responsibilities Work with existing Stripe customers to develop and execute long-term sales strategies to expand Stripe’s revenue Own the full sales cycle, from business case development, to deal structuring and negotiating, to close Develop account plans and cross sell into your list of strategic customers, driving growth through expansion and new revenue streams Drive deal strategy and commercial negotiations for large, complex renewals Develop relationships with executive stakeholders within your book of business, deeply understanding problems they are solving and helping drive to solutions Be responsible for account mapping and coordinating effective meetings with the appropriate external stakeholders expanding the customer relationship Lead and contribute to team projects to develop and refine our sales process and help shape the Stripe sales culture Who you are We’re looking for someone who meets the minimum requirements to be considered for the role. If you meet these requirem

T
📍 Pittsburgh, PA 15237-3423, United States
✓ Quality checkedCompany trend +89.4%

From $17/hr

Starting Hourly Rate / Salario por Hora Inicial: $16.75 USD per hour ALL ABOUT TARGET Working at Target means helping all families discover the joy of everyday life. We bring that vision to life through our values and culture. Learn more about Target here. ALL ABOUT HUMAN RESOURCES You are a team that champions change, proactively removes roadblocks and builds diverse and inclusive talent strategies to deliver on our guest centric mission. You are part of a Hum a n Resource ( HR ) t eam who ar e committed to supporting teams and leaders to build a sales force that is passionate about exceeding guests’ expectations and a place where teams love to work. At Target , we believe in our team members having meaningful experiences that help them build and develop skills for a career. The role of a Human Resources Expert can provide you with the skills and experience of : Understanding f ederal, <s

Human ResourcesHR
T
📍 Houston, TX 77082-6870, United States
✓ Quality checkedCompany trend +89.4%

From $16/hr

Starting Hourly Rate / Salario por Hora Inicial: $16.00 USD per hour ALL ABOUT TARGET Working at Target means helping all families discover the joy of everyday life. We bring that vision to life through our values and culture. Learn more about Target here. ALL ABOUT HUMAN RESOURCES You are a team that champions change, proactively removes roadblocks and builds diverse and inclusive talent strategies to deliver on our guest centric mission. You are part of a Hum a n Resource ( HR ) t eam who ar e committed to supporting teams and leaders to build a sales force that is passionate about exceeding guests’ expectations and a place where teams love to work. At Target , we believe in our team members having meaningful experiences that help them build and develop skills for a career. The role of a Human Resources Expert can provide you with the skills and experience of : Understanding f ederal, <s

Human ResourcesHR
T
📍 Hackettstown, NJ 07840-4978, United States
✓ Quality checkedCompany trend +89.4%

From $17/hr

The Starting Hourly Rate / Salario por Hora Inicial is $17.00 USD per hour. The Pay Range / Rango salarial is $17.00 USD - $25.50 USD per hour. ALL ABOUT TARGET Working at Target means helping all families discover the joy of everyday life. We bring that vision to life through our values and culture. Learn more about Target here. ALL ABOUT HUMAN RESOURCES You are a team that champions change, proactively removes roadblocks and builds diverse and inclusive talent strategies to deliver on our guest centric mission. You are part of a Hum a n Resource ( HR ) t eam who ar e committed to supporting teams and leaders to build a sales force that is passionate about exceeding guests’ expectations and a place where teams love to work. At Target , we believe in our team members having meaningful experiences that help them build and develop skills for a career. The role of a Human Resources Expert can provide you with the skills and experience of : U

Human ResourcesHR
T
📍 San Ramon, CA 94583-2338, United States
✓ Quality checkedCompany trend +89.4%

From $20/hr

Starting Hourly Rate / Salario por Hora Inicial: $19.75 USD per hour ALL ABOUT TARGET Working at Target means helping all families discover the joy of everyday life. We bring that vision to life through our values and culture. Learn more about Target here. ALL ABOUT HUMAN RESOURCES You are a team that champions change, proactively removes roadblocks and builds diverse and inclusive talent strategies to deliver on our guest centric mission. You are part of a Hum a n Resource ( HR ) t eam who ar e committed to supporting teams and leaders to build a sales force that is passionate about exceeding guests’ expectations and a place where teams love to work. At Target , we believe in our team members having meaningful experiences that help them build and develop skills for a career. The role of a Human Resources Expert can provide you with the skills and experience of : Understanding f ederal, <s

Human ResourcesHR
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