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Python in San Francisco

319 active opportunities · Updated October 2026

Explore current python jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.

O
📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -79.2%

$230K – $325K/yr

Quick readStrong listing-quality and freshness signals

About the Team OpenAI’s Safety teams work to ensure our products are safe, trusted, and resilient as frontier AI systems scale globally. We tackle some of the company’s most important challenges across understanding and preventing misuse and misalignment, intercepting fraud and abuse, and protecting vulnerable users. We are hiring Data Scientists to help build the analytical foundations that allow OpenAI to deploy increasingly capable AI responsibly. We are hiring Data Scientists across several teams that contribute to safety in different ways, including: Safety Systems Integrity Product Policy This is a high-impact role operating at the intersection of product, safety, policy, and research. About the Role As a Data Scientist, Safety, you will help solve complex and ambiguous problems where rigorous analysis directly informs critical decisions. Depending on your background and team alignment, you may work on areas such as: Measure harmful or abusive behavior across OpenAI’s products Detect fraud, manipulation, coordinated misuse Evaluate and improve safety classifiers, rules systems, mitigation systems, and human review workflows Design experiments and causal analyses to understand product, policy, and mitigation impacts Build prevalence estimators, dashboards, monitoring systems, and executive decision frameworks Diagnose gaps in safety and integrity systems using behavioral and product data, and help quantify and navigate false positive / false negative tradeoffs Translate ambiguous safety risks into measurable problems and evidence-based recommendations Partner with Product, Engineering, Policy, Research, and Operations teams to improve safety outcomes Build zero-to-one analytical systems in rapidly evolving domains Ideal Candidate We’re looking for strong Data Scientists who thrive in ambiguous, high-leverage environments. You may be a fit if you have: Strong statistical reasoning and analytical judgment Experience with experimentation, causal inference, or obse

PythonSQLAWSRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team Security is at the foundation of OpenAI’s mission to ensure that artificial general intelligence benefits all of humanity. The Identity Infrastructure Engineering team sits at the core of this effort, designing and building the identity and access management solutions that protect our model weights, customer data, and critical systems across multiple cloud environments. We partner with teams across OpenAI—Applied Engineering, Research, IT, and Security—to provide a secure and scalable platform for permissioning, orchestration, and innovative AI research. About the Role We’re looking for a Staff+ Software Engineer to help build and evolve the identity infrastructure that supports OpenAI’s research, engineering, and internal platforms. This role sits at the intersection of cloud infrastructure, identity systems, and software engineering. You’ll work across production systems, infrastructure-as-code, cloud control planes, identity providers, and operational infrastructure to build secure, scalable, and reliable systems used broadly across the company. The ideal candidate has experience building and operating large-scale, mission-critical systems with strong reliability and security requirements, and is comfortable writing production code, designing distributed systems, and driving ambiguous projects from 0 to 1 while building the operational rigor needed to run critical infrastructure over time. In this role, you will: Lead the architecture, development, and operation of identity infrastructure that spans cloud platforms, internal systems, and critical engineering services. Design and evolve systems for authentication, authorization, access governance, auditability, and policy enforcement with a strong focus on reliability, scalability, and secure-by-default design. Build foundational infrastructure and platform capabilities that are broadly used across engineering, research, and security teams. Improve the reliability, observability, performance, and op

PythonAWSRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team Training Runtime builds the distributed systems that power OpenAI's largest model training runs - most recently GPT-5.5! The Data Movement area owns the infrastructure that keeps training jobs supplied with the right data at the right time, and keeps model state moving safely and efficiently across large clusters. Our work spans machine learning systems, distributed storage, high-throughput data loading, reliability engineering, and developer experience. Success means researchers can move quickly while training runs remain fast, reproducible, debuggable, and resilient at scale. About the Role We are looking for a deeply hands-on Technical Lead Manager to own datasets throughout our training infrastructure. This person will set the direction for how training jobs read data: the APIs, storage contracts, versioning model, benchmarks, debugging tools, and reliability guarantees that make data access consistent across current and future training frameworks. You will begin as the primary technical owner for dataset reads, working directly in the code while aligning researchers, training framework owners, storage teams, and infrastructure partners around a durable platform. The problem is deceptively hard at frontier scale: make enormous, heterogeneous datasets easy to consume, correct across distributed workers, observable when something goes wrong, and flexible enough to support pretraining, reinforcement learning, and multimodal training. In this role, you will Design and build a unified dataset read platform for multiple current and future training frameworks. Define dataset APIs, storage-format expectations, registration/versioning, and migration paths that make data access reproducible and maintainable. Build reliability into the read path, including stateful iteration, caching, fast restart, recovery, and clear operational contracts. Build terminal and web-based visualizers that let teams inspect text, multimodal, and reinforcement learning data late

PythonAWSRestMachine Learning
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team The Frontier Systems team at OpenAI builds, launches, and supports the largest supercomputers in the world that OpenAI uses for its most cutting edge model training. We take data center designs, turn them into real, working systems and build any software needed for running large-scale frontier model trainings. Our mission is to bring up, stabilize and keep these hyperscale supercomputers reliable and efficient during the training of the frontier models. About the Role As a Software Engineer on the Frontier Systems team focused on power management, you will work on critical infrastructure to support cutting-edge research. With large-scale supercomputers consuming substantial amounts of power, managing this efficiently is key to maximizing computational capacity. This role is critical to ensuring that our cutting-edge research supercomputing infrastructure runs smoothly, while maintaining reliability and grid-level power stability. Our team empowers strong engineers with a high degree of autonomy and ownership, as well as ability to effect change. This role will require a keen focus on system-level comprehensive investigations and the development of automated solutions. We want people who go deep on problems, investigate as thoroughly as possible, and build automation for detection and remediation at scale. In this role, you will: Develop and implement system-level and software-level solutions to optimize power usage in large-scale supercomputers, ensuring efficient and reliable operations. Build automation to monitor power consumption patterns during training workloads and design algorithms to stabilize these fluctuations, preventing issues with grid reliability. Work with researchers and engineers to design tools for real-time monitoring, detection, and remediation of power-related hardware and system faults. Collaborate cross-functionally to translate complex electrical system requirements into code, while driving continuous improvements in power man

PythonSQLAWSGit
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team OpenAI’s Applications Engineering organization builds and operates the products (such as ChatGPT & Codex) that bring our cutting-edge research to millions of users and developers worldwide. The Applied Foundations team owns the core product and platform layers that make those experiences possible — from identity & access, to safety to payments & commerce across all of our apps. Our teams span product engineering, infrastructure, and safety, working together to deliver technology that is reliable, secure, and trusted at global scale. About the Role We’re hiring Backend Software Engineers to design and implement safe services and infrastructure that power our core products. What You’ll Do Architect, build, and improve scalable backend systems and APIs. Drive performance, reliability, and safety across distributed services. Implement data storage, retrieval, compute, and integration solutions. Participate in long-term architectural planning and technical design reviews. Collaborate with cross-functional teams to design solutions that protect against and mitigate adversarial attacks without compromising user experience. You Might Thrive Here If You: Have strong experience with distributed systems, APIs, and backend languages (e.g., Go, Python, Rust, C++). Have experience setting up and maintaining production backend services and data pipelines. Have a humble attitude, an eagerness to help your colleagues, and a desire to do whatever it takes to make the team succeed. Enjoy building resilient services that handle large scale and complexity. Are self-directed and enjoy figuring out the best way to solve a particular problem Own problems end-to-end, and are willing to pick up whatever knowledge you're missing to get the job done. About OpenAI OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We push the boundaries of the capabilities of AI systems and seek

PythonAWSRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team Full Stack engineers within the Fleet Scheduling team are dedicated to building intuitive and scalable interfaces that empower researchers to efficiently manage AI workloads across some of the largest supercomputers in the world. Our focus is on developing robust, high-performance systems that provide real-time insights, resource tracking, and seamless interaction with complex infrastructure. We aim to optimize resource allocation, minimize operational overhead, and create user-friendly tools that enhance researcher productivity and system transparency. About the Role You will design, develop, and operate web-based systems that provide a powerful and intuitive interface to OpenAI’s supercomputing clusters. You will collaborate closely with researcher, product and infrastructure teams to deliver scalable solutions that enable seamless monitoring, job scheduling, and resource management. This is an opportunity to work at the cutting edge of AI infrastructure, designing tools that scale to exascale workloads while maintaining usability and performance. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Design and develop full-stack web applications to track, monitor, and manage large-scale AI workloads in real time. Collaborate with researchers and infrastructure teams to translate complex operational needs into intuitive UIs and scalable backends. Build data visualization tools (e.g., Gantt charts, dashboards) to provide insights into job scheduling and resource allocation. Optimize backend services to handle massive data throughput while ensuring low-latency performance and high availability. Implement frontend components that provide seamless interactions with scheduling, storage, and compute systems. Ensure system security, reliability, and scalability across globally distributed supercomputing infrastructure. You might thrive i

PythonReactNode.jsAngular
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team Business Systems / Enterprise Platform Technology builds the internal systems, data foundations, workflow infrastructure, and enterprise platforms that help OpenAI operate at scale. The EPT AI Pod builds AI-native internal apps, MCP connectors, multi-agent workflows, and reusable platform capabilities across Finance, People, and GTM. About the Role As an Enterprise Applied AI Engineer, you will build internal apps for enterprise operations and the shared platform components those apps run on. This includes MCP connectors, multi-agent orchestration, data architecture, evals, monitoring, auditability, and governance. We’re looking for a hands-on engineer who is strong in Python, system design, enterprise integrations, data architecture, and applied AI systems. You should be excited to turn ambiguous business workflows into reliable internal products and shared infrastructure. In this role, you will: • Build internal apps for enterprise operations across Finance, People, and GTM • Build MCP connectors and enterprise integrations with strong auth, permissions, idempotency, retries, and rate-limit handling • Design end-to-end multi-agent workflows with tool routing, human approvals, audit trails, and safe action boundaries • Design data architecture for operational AI systems, including ingestion, schemas, quality checks, lineage, and governance • Build evals, monitoring, metrics, and regression tests for agentic workflows • Create reusable infrastructure, patterns, and components that other enterprise teams can build on • Partner with system owners and business owners to turn messy enterprise workflows into reliable internal products You might thrive in this role if you: • Have strong Python engineering skills for backend services, MCP connectors, agent/tool workflows, eval harnesses, and data ingestion jobs • Have strong system design skills across shared infrastructure, app architecture, reliability, and scaling • Have experience building internal apps,

PythonAWSRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team The Technical Support team is responsible for ensuring that developers and enterprises can reliably build mission critical solutions using OpenAI models. We provide technical guidance, resolve complex issues and support customers in maximizing value and adoption from deploying our highly-capable models. We work closely with Technical Success, Product, Engineering and others to deliver the best possible experience to our customers at scale. We think from an automation-first mindset and leverage the latest in AI to scale our support operations. Join the Senior Support Engineering (SSE) team at OpenAI and help shape the future of Technical Support in the age of AI. About the Role We are looking for a Senior Support Engineer to collaborate directly with our strategic enterprise accounts and product teams, helping solve some of the most difficult problems faced by our Customers. You will be part of the best technical troubleshooting team at OpenAI, and our Customers and Engineering teams will look to you for technical guidance in addressing the most technically difficult issues in our environment. As a Senior Support Engineer, you will design and run operational processes to monitor our top strategic customers and a 24x7 response team. You’ll work closely with our Infrastructure and Engineering teams to deliver the best possible experience to customers at scale. Working directly with our most strategic Customers - You will be crucial to the success of the most innovative, disruptive, and high-scale AI solutions being built with the OpenAI API platform. The nature of this role will be low volume, high difficulty. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Be among the foremost technical and troubleshooting experts for our API platform at OpenAI. You are the last line of defense before the core Engineering team. Proactively iden

PythonAWSRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team Our Applied team brings OpenAI technologies to consumers and businesses around the world. We collaborate across research, engineering, design and business functions to turn cutting-edge AI advancements into impactful real-world applications. Our team has been behind notable product launches ( ChatGPT , API , Sora ), creating tools that help developers write code, enable businesses to operate more efficiently, and empower individuals to learn and create. As AI capabilities rapidly evolve, we focus on ensuring that our products are safe, accessible, and beneficial to all. About the Role As a Data Scientist on the Applied Product team, you will contribute to a data-driven product development culture for consumer and enterprise products at OpenAI. This is critical as our products reach millions of users and businesses worldwide. We are focused on aligning both research and product development to drive measurable impact for these individuals and organizations alike. You should expect to define our north-star metrics, design A/B tests, and establish source-of-truth dashboards that the entire company can use to answer their own product questions. Most importantly, you should expect to be a core member of the product development team. This role is based in San Francisco, CA or Seattle, WA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Embed with the product development team as a trusted partner, uncovering new ways to improve the product and drive growth Define and interpret A/B tests that help answer critical questions about the impact of model and UX changes to our product Establish a data-driven product development culture by defining, tracking, and operationalizing feature-, product-, and company-level metrics Develop and socialize dashboards, reports, and other ways of enabling the team and company to answer product data questions in a self-serve way You might thrive

PythonSQLAWSRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

Overview: The Data Acquisition team within the Foundations organization at OpenAI is responsible for all aspects of data collection to support our model training operations. Our team manages web crawling and GPTBot services and works closely with Data Processing, Architecture, and Scaling teams. We are looking for a skilled Full-Stack Engineer to join our Data Acquisition team to build and optimize the interfaces and tools that power our data infrastructure. Responsibilities: Develop and maintain full-stack applications that support data acquisition, including internal tools and dashboards. Collaborate closely with cross-functional teams, including Data Processing, Architecture, and Scaling, to ensure seamless data ingestion and workflow management. Design and implement APIs to facilitate data interactions between internal services and external data sources. Enhance user experience by developing intuitive web-based interfaces for managing and monitoring data pipelines. Optimize backend services for performance, scalability, and security in a distributed computing environment. Work with legal and compliance teams to ensure our data acquisition processes adhere to privacy regulations and best practices. Deploy and maintain infrastructure using Kubernetes and Infrastructure-as-Code (IaC) methodologies. Analyze system performance, conduct experiments, and improve data workflows to maximize efficiency. Qualifications: BS/MS/PhD in Computer Science or a related field. 4+ years of industry experience in full-stack development. Proficiency in frontend frameworks (React, Vue, or similar) and backend technologies such as Python, Node.js, or Go. Strong expertise in RESTful APIs, GraphQL, and database design (SQL and NoSQL). Experience building data-intensive applications that handle large-scale datasets. Familiarity with cloud platforms (AWS, GCP, or Azure) and container orchestration (Kubernetes, Docker). Prior experience with web crawling and large-scale data processing is a

PythonReactNode.jsVue
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team We’re hiring a Developer Productivity engineer to support OpenAI’s Inference Runtime teams. These teams own the systems responsible for serving models reliably, efficiently, and safely across Codex, ChatGPT, API, and internal research workloads. We’re hiring a Developer Productivity Engineer to help scale the engineering systems, safeguards, and developer workflows that enable our teams to move quickly without compromising reliability or performance. This role sits at the intersection of developer experience, CI/CD infrastructure, release engineering, production readiness, and inference systems reliability. You’ll work on the tooling and operational foundations that support model launches, inference optimizations, cloud provider integrations, and large-scale deployments across a rapidly evolving inference stack. About the Role We’re looking for an autonomous, high-ownership engineer who cares deeply about making other engineers faster, safer, and more confident. A major focus of this role will be improving the tooling and infrastructure around deploy gates for inference engine images. These systems help ensure that every image released to production and research is correct, numerically sound, free of regressions, and performant across key metrics like time-to-first-token (TTFT) and time-between-tokens (TBT). You’ll help harden the systems that catch issues before they reach production, reduce noise from flaky or infrastructure-related test failures, and improve automation around triage, ownership, debugging, and escalation when failures occur. You’ll also work on improving observability, rollout safety, release automation, and developer self-service tooling across a rapidly evolving inference stack. This is not generic internal tools work. The systems you build directly impact OpenAI’s ability to support new model launches, safely ship inference optimizations to the world, onboard new infrastructure providers, and operate one of the largest and most p

PythonAWSCI/CDRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team The Core Network Engineering team owns the end-to-end networking stack that connects OpenAI’s compute infrastructure — spanning global WAN/edge connectivity, data-center networking, and high-performance host/xPU networking used for large-scale training and inference workloads. This team is responsible for ensuring networking is never the bottleneck to model training efficiency, cluster reliability, or fleet expansion. They design and operate the systems that provide predictable, high-throughput, low-latency connectivity across some of the world’s most advanced AI infrastructure. About the Role We’re looking for engineers to help build and operate the networking foundation behind OpenAI’s frontier AI systems. Depending on your background and area of focus, you may work across host networking, datacenter fabrics, or global WAN infrastructure. The problems span low-level systems software, distributed infrastructure, protocol readiness, observability, performance engineering, automation, and large-scale network operations. You’ll work on systems where microseconds of latency, tail performance, and network reliability directly impact model training efficiency and production serving performance. This role is ideal for engineers who enjoy operating close to the hardware/software boundary and solving performance-critical infrastructure problems at massive scale. In this role, you will: Design, build, and operate networking systems that support large-scale AI training and inference infrastructure Improve performance, reliability, and scalability across host networking, datacenter fabrics, and WAN systems Develop automation for provisioning, configuration management, validation, upgrades, and lifecycle management of networking infrastructure Build tooling and observability systems for network health, performance analysis, debugging, and automated remediation Optimize network performance across technologies such as RDMA, RoCE, InfiniBand, Ethernet, and high-perf

PythonAWSLinuxRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team The Hardware Health and Observability team owns the end-to-end health lifecycle of OpenAI’s global compute fleet. Our mission is to maximize healthy, usable compute across accelerator vendors, generations, cloud providers, and regions through reliable health signals, automated remediation, and scalable operational tooling. We build the systems that observe, detect, remediate, and verify hardware issues across GPUs, CPUs, networking, and platform infrastructure, enabling frontier model training and inference workloads to run reliably at hyperscale. We are the last line of defense for the success of OAI’s production and research workloads. About the Role On the Hardware Health and Observability team, you’ll build critical infrastructure that keeps OpenAI’s largest compute clusters healthy and operational at scale. Even small numbers of unhealthy systems can impact large-scale training and inference workloads. This team focuses on minimizing downtime, improving fleet efficiency, and ensuring compute resources remain continuously available to researchers and product teams. Engineers on this team own problems end-to-end, from defining health signals and debugging failures to building automated remediation systems that operate across millions of GPUs globally. In this role, you will: Define and maintain health signals across GPUs, CPUs, networking, and platform infrastructure. Build and evolve health checks that detect, remediate, and verify failures at scale. Ensure critical health checks execute with minimal latency to maximize workload uptime. Investigate hardware failures and system-level issues across large-scale compute environments. Own node lifecycle workflows including drain, quarantine, repair, RMA, and return-to-service processes. Build automation and tooling that enables global cluster management with minimal manual intervention. Partner with workload, reliability, and provider teams to integrate health signals into training and inference system

PythonSQLAWSLinux
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team The Safety Systems team is responsible for various safety work to ensure our best models can be safely deployed to the real world to benefit the society, and is at the forefront of OpenAI's mission to build and deploy safe AGI, driving our commitment to AI safety and fostering a culture of trust and transparency. The Safety Oversight Research team aims to fundamentally advance our capabilities to maintain oversight over frontier AI models, and leverage these advances to ensure OpenAI’s deployed models are safe and beneficial. This requires a breadth of new ML research in the areas of human-AI collaboration, reasoning, robustness, and scalable oversight to keep pace with model capabilities. We invest heavily in developing novel model and system-level methods of identifying and mitigating AI misuse and misalignment. Our goal is to learn from deployment and distribute the benefits of AI, while ensuring that this powerful tool is used responsibly and safely. About the Role OpenAI is seeking a senior researcher with a passion for AI safety and experience in safety research. Your role will set directions for research to maintain effective oversight of safe AGI and work on research projects to identify and mitigate misuse and misalignment in our AI systems. You will play a critical role in defining how a safe AI system should look in the future at OpenAI, making a significant impact on our mission to build and deploy safe AGI. In this role, you will: Develop and refine AI monitor models to detect and mitigate known and emerging patterns of misuse and misalignment. Set research directions and strategies to make our AI systems safer, more aligned, and more robust. Evaluate and design effective red-teaming pipelines to examine the end-to-end robustness of our safety systems, and identify areas for future improvement. Conduct research to improve models’ ability to reason about questions of human values, and apply these improved models to practical safety challen

PythonAWSRestMachine Learning
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team At OpenAI, we’re building the connective tissue between our mission and our people. People Innovation Labs is a fast-moving engineering team embedded in the People organization, focused on rethinking how we find and retain the best talent and empower everyone to do their best work. From recruiting to culture, we’re designing systems that give our People Team a significant edge by infusing OpenAI’s models and first-principles thinking into every aspect of our work. Our projects range from greenfield 0-1 products like OpenHouse (our internal knowledge hub) to AI-powered automations and scalable recruiting tools. We’re defining the future of work at OpenAI, creating a blueprint for how AI can supercharge productivity, culture, and innovation. About the Role We’re seeking a Data Engineer to build data-intensive systems that will power People Innovation Labs’ internal products and enable the People Analytics function to do their best work. These data pipelines are crucial for our build-out of people products backed by business systems of record and for ongoing people data analytics. One example of an employee-facing product you’ll help us build is OpenHouse, which serves as a culture and communication hub and an organization-wide front door into all other aspects of People Innovation Labs’ work. OpenHouse and other products in our portfolio are built by full stack product engineers who are deeply curious about culture, recruiting and people development, and want to know everything from the business strategy and metrics down through the code that gets us there. In this role, you will work with People Innovation Labs leadership and software engineers and the People Analytics team to build the data systems that enable this work. In this role, you will: Design, build and manage people data pipelines, ensuring all data is seamlessly integrated into our Databricks warehouse. Develop canonical datasets to track key people metrics and People Innovation Labs produc

PythonJavaAWSRest
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