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Python in San Francisco

319 active opportunities · Updated October 2026

Explore current python jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

AI Systems Engineer - Codex Core Agents About The Team The Codex Core Agents team builds the agent harness that turns model capability into real-world action. We own the systems around the model: prompting and interpreting model outputs, executing actions safely in real environments, and feeding production experience back into better models and better agent behavior. This team sits close to research and works across the stack: harness, model interaction, inference, sandboxed execution, orchestration, evals, production reliability, and the performance envelope around tokens, latency, cost, capacity, and quality. The harness is open source and increasingly part of how models are trained and evaluated, making this one of the highest-leverage layers in Codex. About The Role We’re looking for engineers to build the AI systems that make Codex agents dependable in production. The ideal candidate is an agent-systems builder: hands-on across low-level systems and ML workflows, able to debug Codex behavior end to end across the harness, model behavior, inference/runtime stack, GPU fleet, and product surface. You’ll work with research, infrastructure, and product to design agent harness capabilities, run experiments and ablations across the model + system prompt + harness stack, build frameworks for assessing production agent performance, and turn messy failures into durable improvements. What You’ll Do Design and build the core agent harness and execution loop that lets Codex agents interpret model outputs, use tools, execute code, and complete long-horizon tasks safely. Build sandboxing, isolation, orchestration, state, and workflow infrastructure for agents operating in real development environments. Develop evaluation, experimentation, and debugging systems that distinguish harness issues, model behavior, inference/runtime issues, and product failures. Run ablations across prompts, model-facing interfaces, context construction, tool-use strategies, and harness behavior to

PythonAWSRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI's Research Data Team exists to accelerate the evaluation, safety and capabilities of our models and products. Made up of technical operators and software engineers, we design the methods in which we acquire and create data. About the Role As a Research Program Manager (RPM), Data Acquisition, you will partner with research, engineering, and operations to design and implement pragmatic solutions for acquiring data. You will be a key interface between our research roadmap and external data offerings. This role is based in our San Francisco HQ and will be part of a team of RPMs pushing the frontier of data acquisition. In this role, you will: Partner deeply with research: Work with researchers to scope data needs, define success criteria, and translate priorities into clear execution plans. Shape the data acquisition pipeline: Identify, evaluate, and advance high impact data opportunities - balancing research value, feasibility, quality, and responsible execution. Unblock yourself: Move work forward even when the path is unclear — using technical judgement, creative problem solving, and scrappy execution to make progress while longer-term solutions are still forming. Build lightweight systems and visibility: Use SQL, Python, dashboards, and simple tooling to track performance, quality, and blockers. Drive technical roadmaps: Collaborate with engineers to enhance data platforms, resolve blockers, and ensure security best practices such as access management. Scale your impact: Equip vendors and internal teams with the context, standards, and operating rhythms needed to focus on the most important problems. You’ll thrive in this role if you: Are proficient in SQL and Python for analysing datasets, querying databases, building dashboards, and generating actionable insights. Are comfortable using APIs, automation, and AI tools such as Codex to accelerate workflows, remove manual overhead, and upskill quickly in unfamiliar technical areas.Experience sou

PythonSQLAWSRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The IT and Security organization builds the systems, data foundations, and automation that help OpenAI operate securely and reliably at scale. We support critical domains across identity, access, infrastructure security, enterprise systems, and internal productivity. As OpenAI grows, audit readiness and control assurance increasingly depend on reliable data: accurate system inventories, access populations, change records, configuration state, exception signals, and evidence generated directly from source systems. Our goal is to move beyond manual evidence collection and build scalable data products, automated validation, and continuous control monitoring that make security and IT controls measurable, repeatable, and defensible. About the Role We are looking for an IT Controls Data Engineer to build the data infrastructure that powers audit readiness, IT controls, evidence automation, and continuous control monitoring. In this role, you will design and maintain the pipelines, datasets, models, validation logic, dashboards, and evidence exports that make IT controls measurable, repeatable, and defensible. You will work across Security, IT, Infrastructure, Engineering, Finance Risk Management, and auditors to turn complex system behavior into reliable control data products. This is a technical builder role. The ideal candidate is strong in data engineering and analytics engineering, comfortable working with enterprise and security system data, and able to explain data lineage, source-system behavior, and control logic clearly to technical and audit stakeholders. You’ll be responsible for Building reliable data pipelines, models, and datasets for IT controls, including access, identity, configuration, change, ticketing, exception, and evidence data. Creating data quality, lineage, reconciliation, and completeness checks that make control data defensible for SOX and other audit use cases. Designing automated evidence generation workflows that produce compl

PythonSQLAWSAzure
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Business Data Science team uses data and analytics to optimize business performance, drive growth, and foster meaningful partnerships, with the goal of ensuring the sustained and impactful expansion of OpenAI's initiatives to maximize the benefits of AGI for all of humanity. We partner with Sales (GTM), Marketing, Partnerships, Support, Finance, Product, and Growth. About the Role As a member of our Business Data Science team, you will help build a data-driven culture around insight generation, decision making, and strategy at OpenAI. This role is focused on driving customer success within our business products (ChatGPT Team, ChatGPT Enterprise, and API). You will work on projects such as identifying opportunities for interventions within a customer lifecycle to drive activation & onboarding, identifying target audiences for new feature launches, and measuring the efficacy of emails, events, and other interventions to drive ongoing engagement with our products. This role is based in San Francisco, CA or New York, NY. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Embed with our Customer Success organization as a trusted partner, uncovering new ways to drive customer adoption and engagement of our business products. Establish key metrics, run experiments, and perform analysis to help us understand the incrementality of our efforts to drive adoption/engagement. Proactively surface insights and opportunities to drive engagement and growth. Build tools and systems for stakeholders to self-serve routine data and insights freeing up time to work on more leveraged analyses. Become an expert in OpenAI’s data and systems. Through partnership with Data Eng, Finance and other business teams, you will self-serve all the underlying data for our business and derive insights from them. Partner with other data scientists across the company to share knowledge and continually

PythonSQLAWSRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

We’re looking for a Software Engineer to architect and build backend systems that enforce data privacy and automate compliance at scale. You’ll work closely with product, infrastructure, security, and legal teams to embed privacy-by-design into our data and access layers. This is a hands-on, high-impact role for an experienced engineer who is passionate about protecting user data while enabling innovation. What You’ll Do Design, build, and operate backend services that enforce policy-driven data access, lifecycle controls, and privacy protections. Develop distributed authorization and identity-aware enforcement mechanisms integrated directly into data services and control planes. Implement auditability, policy hooks, and enforcement observability to ensure compliance is continuously verifiable. Partner with Security, Legal, and Compliance to convert privacy requirements into scalable technical designs and developer-friendly APIs. Harden data platforms and backend services through schema-level controls and data handling constraints by default. Collaborate with infrastructure teams to ensure consistent enforcement across systems while minimizing duplicated implementations. Contribute patterns, libraries, and education that elevate trustworthy data access patterns across the organization. You Might Thrive in This Role If You Have 5+ years of industry experience building and operating backend or infrastructure systems in production. Strong software engineering fundamentals , with fluency in at least one major programming language (e.g., Python, Go, Rust, C++, Java). Experience with distributed authorization, RBAC/ACL systems, encryption-based access, or policy engines. Familiarity with global privacy regulations and their architectural implications. Ability to influence and collaborate with teams across legal, compliance, product, and engineering. A bias toward practical, impactful solutions that balance privacy protections with product needs. Nice to Have Experience wi

PythonJavaAWSAzure
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team Codex is OpenAI’s first-party developer product focused on agentic software engineering. We’re building tools that help engineers design, write, test, and ship code faster—safely and at scale. We partner tightly with research and product to translate model advances into tangible developer productivity. About the Role As a Data Scientist on Codex, you will measure and accelerate product-market fit for AI developer tools. You’ll define what “developer productivity” means for our product, run experiments on new coding models and UX, and pinpoint where the model helps or hurts across languages and tasks. Your insights will directly shape how an entire industry builds software. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will Embed with the Codex product team to discover opportunities that improve developer outcomes and growth Design and interpret A/B tests and staged rollouts of new coding models and product features Define and operationalize metrics such as suggestion acceptance, edit distance, compile/test pass rates, task completion, latency, and session productivity Build dashboards and analyses that help the team self-serve answers to product questions (by language, framework, repo size, task type) Diagnose failure modes and partner with Research on targeted improvements (model quality signals, user feedback, evals) You might thrive in this role if you have 5+ years in a quantitative role at a developer-facing or high-growth product Fluency in SQL and Python; comfort with experiment design and causal inference Experience defining product metrics tied to user value Ability to communicate clearly with PM, Eng, and Design—and to influence product direction You could be an especially great fit if you have Strong programming background; ability to prototype, run simulations, and reason about code quality Familiarity with IDE/extensi

PythonSQLAWSRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Interpretability team studies internal representations of deep learning models. We are interested in using representations to understand model behavior, and in engineering models to have more understandable representations. We are particularly interested in applying our understanding to ensure the safety of powerful AI systems. Our working style is collaborative and curiosity-driven. About the Role OpenAI is seeking a researcher passionate about understanding deep networks, with a strong background in engineering, quantitative reasoning, and the research process. You will develop and carry out a research plan in mechanistic interpretability, in close collaboration with a highly motivated team. You will play a critical role in helping OpenAI ensure future models remain safe even as they grow in capability. This will make a significant impact on our goal of building and deploying safe AGI. In this role, you will: Develop and publish research on techniques for understanding representations of deep networks. Engineer infrastructure for studying model internals at scale. Collaborate across teams to work on projects that OpenAI is uniquely suited to pursue. Guide research directions toward demonstrable usefulness and/or long-term scalability. You might thrive in this role if you: Are excited about OpenAI’s mission of ensuring AGI benefits all of humanity, and are aligned with OpenAI’s charter . Show enthusiasm for long-term AI safety, and have thought deeply about technical paths to safe AGI. Bring experience in the field of AI safety, mechanistic interpretability, or spiritually related disciplines. Hold a Ph.D. or have research experience in computer science, machine learning, or a related field. Thrive in environments involving large-scale AI systems, and are excited to make use of OpenAI’s unique resources in this area. Possess 2+ years of research engineering experience and proficiency in Python or similar languages. Are deeply curious. About OpenA

PythonAWSRestMachine Learning
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team Our infrastructure team helps deliver OpenAI’s most capable models and products to the world by scaling infrastructure and turning demand into useful FLOPS. We collaborate across research, engineering, design, and business to turn cutting-edge AI advancements into impactful, real-world applications. Our team ensures the right compute is available—at the right time and place—to support some of the world’s most demanding workloads. We empower all of OpenAI’s products and research by scaling the infrastructure behind them. Our work makes it possible to launch new models and products reliably and at scale. About the Role As a Data Scientist on the Infra team, you will play a key role in shaping how we scale the infrastructure that powers OpenAI’s products and research. This is critical as we operate one of the largest and most advanced compute fleets in the world, supporting millions of users and businesses globally. We focus on aligning infrastructure measurement, planning, scaling, allocation, and efficiency to drive measurable impact across the company. You should expect to guide the definition of foundational datasets for infrastructure resources, develop metrics that inform key decisions, build forecasting and optimization models, and establish source of truth dashboards and analyses that enable teams to understand and improve infra usage. Most importantly, you should expect to be a core partner to engineering, research, and product teams in shaping the infrastructure that powers everything OpenAI builds. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Build and maintain foundational datasets and metrics that reflect infrastructure usage, efficiency, and scaling. Develop forecasting and optimization models to support infra planning and resource allocation. Partner with engineering, research, and product teams to shape infrast

PythonSQLAWSRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI is building the infrastructure foundation for the next generation of AI. The Data Center Engineering team defines the strategy, reference architectures, technical requirements, and delivery standards for the large-scale data centers that support OpenAI research, products, and infrastructure partners. As a Data Center Controls Network Engineer, you will design, validate, and scale the controls and OT network architectures that support high-density AI data centers. You will work across controls systems, OT infrastructure, telemetry, commissioning, deployment, and operations, partnering with mechanical, electrical, IT/networking, security, and external delivery teams. About the Role We are seeking a mid to senior OT Network Engineer with a strong controls systems background to lead the design and operation of resilient, secure, and scalable OT network architectures for high-density AI data centers. This role translates compute, power, cooling, and operational requirements into practical OT network designs, evaluates vendor solutions, and drives technical decisions across controls infrastructure, telemetry, commissioning, and operations. The ideal candidate has strong hands-on experience in mission-critical OT environments, including industrial networking, virtualized infrastructure, and OT network operations, with expertise in routing, switching, segmentation, firewall policy, time synchronization, monitoring, and network lifecycle support. Key Responsibilities Define controls, automation, and OT network requirements for AI data center campuses. Develop reference architectures, engineering standards, and reusable design templates. Review and develop basis-of-design and functional design documents, including OT network diagrams, IP/VLAN schemes, telemetry architectures, data flow diagrams, and commissioning requirements. Design OT and infrastructure network architectures, including physical topology, logical topology, IP addressing, subnetting, VLA

PythonSQLPostgreSQLMySQL
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s User Operations team shepherds our customers’ adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others, to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. About the Role We’re looking for dedicated, experienced, and deeply curious individuals to help solve some of the most complex challenges faced by our customers while building the future of post-AGI support alongside us. In this role, you’ll work directly with customers through support tickets and live calls, troubleshooting high-impact issues and resolving novel, often ambiguous technical problems in one of the fastest-moving environments in technology. As AI adoption rapidly accelerates, the work you do will directly support mission-critical systems being built on OpenAI’s platform, serving as a critical line of defense for customers operating at massive scale. Beyond resolving technical issues, you’ll help define what world-class support looks like in an AGI-driven future. You’ll partner closely with Engineering, Product, and Operations to improve systems, reduce bugs, and elevate the customer experience, while leveraging automation, agents, and our own AI technology to transform how support operates at scale. You’ll be responsible for: Working directly with customers to troubleshoot and resolve their most complex technical issues, including API failures, integration challenges, authentication errors, and production incidents. Providing end-to-end ownership through debugging logs, analyzing system behavior, reproducing issues, and

PythonAWSRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s Financial Engineering (FinEng) team powers how revenue flows through our products—pricing & packaging, checkout, payments, subscriptions, and the financial infrastructure behind them. We partner with Product, Engineering, Risk, Finance, and Go-to-Market to make paying for OpenAI products seamless, reliable, and efficient worldwide. About the Role As a Data Scientist on FinEng, you’ll own the analytics and experimentation that improve our checkout and payments , subscriptions , and pricing & monetization systems. You’ll define the metrics that matter, build the source-of-truth data assets, and design experiments that increase conversion, reduce churn and payment failures, and expand global payment method coverage. Your work will directly influence revenue, customer experience, and how we scale internationally. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will Own checkout & payments analytics and experimentation across methods and locales (e.g., bank transfers, emerging rails), improving conversion while monitoring risk and latency. Build and run the experimentation program for in-house checkout—define success metrics and guardrails, execute staged rollouts, and use offline incrementality when online tests aren’t feasible. Create operational visibility and source-of-truth data with FinEng Data Engineering—land team-level metrics, SLAs, and self-serve dashboards that drive proactive action. Lead subscription, retention, and monetization analytics—ship launch-readiness for new subscription features, reduce involuntary churn (e.g., targeted retrials/nudges), and develop elasticity/FX frameworks toward pricing optimality. You might thrive in this role if you have 5+ years in a quantitative role (data science, product analytics, or experimentation) in high-growth or fintech environments Fluency in SQL and Python ,

PythonSQLAWSRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the team The Fleet team at OpenAI supports the computing environment that powers our cutting-edge research and product development. We oversee large-scale systems that span data centers, GPUs, networking, and more, ensuring high availability, performance, and efficiency. Our work enables OpenAI’s models to operate seamlessly at scale, supporting both internal research and external products like ChatGPT. We prioritize safety, reliability, and responsible AI deployment over unchecked growth. About the role As a software engineer on the Fleet High Performance Computing (HPC) team, you will be responsible for the reliability and uptime of all of OpenAI’s compute fleet. Minimizing hardware failure is key to research training progress and stable services, as even a single hardware hiccup can cause significant disruptions. With increasingly large supercomputers, the stakes continue to rise. Being at the forefront of technology means that we are often the pioneers in troubleshooting these state-of-the-art systems at scale. This is a unique opportunity to work with cutting-edge technologies and devise innovative solutions to maintain the health and efficiency of our supercomputing infrastructure. Our team empowers strong engineers with a high degree of autonomy and ownership, as well as ability to effect change. This role will require a keen focus on system-level comprehensive investigations and the development of automated solutions. We want people who go deep on problems, investigate as thoroughly as possible, and build automation for detection and remediation at scale. In this role, you will: Build and maintain automation systems for provisioning and managing server fleets. Develop tools to monitor server health, performance, and lifecycle events. Collaborate with clusters, networking, and infrastructure teams. Partner with external operators to ensure a high level of quality. Identify and fix performance bottlenecks and inefficiencies. Continuously improve automati

PythonSQLAWSLinux
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the team The Fleet team at OpenAI supports the computing environment that powers our cutting-edge research and product development. We oversee large-scale systems that span data centers, GPUs, networking, and more, ensuring high availability, performance, and efficiency. Our work enables OpenAI’s models to operate seamlessly at scale, supporting both internal research and external products like ChatGPT. We prioritize safety, reliability, and responsible AI deployment over unchecked growth. About the role As a software engineer on the Fleet Hardware team, you will be responsible for the reliability and uptime of all of OpenAI’s compute fleet. Minimizing hardware failure is key to research training progress and stable services, as even a single hardware hiccup can cause significant disruptions. With increasingly large supercomputers, the stakes continue to rise. Being at the forefront of technology means that we are often the pioneers in troubleshooting these state-of-the-art systems at scale. This is a unique opportunity to work with cutting-edge technologies and devise innovative solutions to maintain the health and efficiency of our supercomputing infrastructure. Our team empowers strong engineers with a high degree of autonomy and ownership, as well as ability to effect change. This role will require a keen focus on system-level comprehensive investigations and the development of automated solutions. We want people who go deep on problems, investigate as thoroughly as possible, and build automation for detection and remediation at scale. In this role, you will: Build and maintain automation systems for provisioning and managing server fleets. Develop tools to monitor server health, performance, and lifecycle events. Collaborate with clusters, networking, and infrastructure teams. Partner with external operators to ensure a high level of quality. Identify and fix performance bottlenecks and inefficiencies. Continuously improve automation to reduce manual work

PythonSQLAWSLinux
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s Hardware organization develops AI-native silicon and system-level solutions for the unique demands of advanced AI workloads. Building on efforts like Jalapeño, the team is developing future generations of AI-native silicon and tightly integrated systems to power the next generation of frontier models. By co-designing chips, systems, tools, and methodologies, the team helps deliver faster, more efficient, and production-ready hardware for OpenAI’s supercomputing platform. About the Role As a software engineer on the Scaling team, you’ll help build and optimize the low-level stack that orchestrates computation and data movement across OpenAI’s supercomputing clusters. Your work will involve designing high-performance runtimes, building custom kernels, contributing to compiler infrastructure, and developing scalable simulation systems to validate and optimize distributed training workloads. You will work at the intersection of systems programming, ML infrastructure, and high-performance computing, helping to create both ergonomic developer APIs and highly efficient runtime systems. This means balancing ease of use and introspection with the need for stability and performance on our evolving hardware fleet. This role is based in San Francisco, CA, with a hybrid work model (3 days/week in-office). Relocation assistance is available. In this role, you will: Design and build APIs and runtime components to orchestrate computation and data movement across heterogeneous ML workloads. Contribute to compiler infrastructure, including the development of optimizations and compiler passes to support evolving hardware. Engineer and optimize compute and data kernels, ensuring correctness, high performance, and portability across simulation and production environments. Profile and optimize system bottlenecks, especially around I/O, memory hierarchy, and interconnects, at both local and distributed scales. Develop simulation infrastructure to validate runtime b

PythonAWSRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Intelligence and Investigations team seeks to rapidly detect and disrupt abuse in AI technologies to ensure their safe use. We are dedicated to identifying emerging abuse trends, analyzing risks, and working with our internal partners to implement effective mitigation strategies to protect against misuse. Our efforts contribute to OpenAI's overarching goal of developing AI that benefits all of humanity. About the Role As an Intelligence Systems Engineer, you’ll be focused on advancing our Intelligence & Investigations efforts at OpenAI, ensuring the safe and responsible use of AI across our products and services. We are seeking a self-starter to prototype, develop, and maintain new tools and processes that integrate OpenAI’s models and infrastructure to enable internal teams to make sense of large, open-domain datasets, fight abuse, and inform high-stakes decisions. You will be a crucial technical bridge between our data scientists and subject matter experts and technical teams like Platform Integrity, Safety Systems, and Research by leading the development of innovative tools and processes that bolster goals in scaled collections, investigations, and analysis. The ideal candidate has strong analytical and data skills, with a background in both prototyping and building scalable systems that can swiftly detect emerging threats, process vast amounts of information, and deliver insights to stakeholders. We value professionals with outstanding communication skills, a commitment to continuous learning, and who are dedicated to promoting the responsible use of AI. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Prototype, build, and maintain at-scale intelligence systems that detect, triage, and monitor targeted signals from both open-source and internal data Analyze requirements and deliver end-to-end solutions that address

PythonSQLAWSRest
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