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Python in San Francisco

319 active opportunities · Updated October 2026

Explore current python jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.

O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Systems Integration team is responsible for building the infrastructure, tooling, and validation systems that ensure our device software is reliable, testable, and ready to ship. We design and maintain automated test frameworks, hardware-in-the-loop labs, and release pipelines that keep quality signals trustworthy and enable rapid, safe product launches. Our work spans developer tools, automation, systems integration, and cross-team collaboration to ensure every release meets the highest standards. About the Role As a Software Engineer, Quality and Developer Tools , you will build and own the systems that validate our device software—from test frameworks and regression infrastructure to hardware-in-the-loop labs and release gates. You’ll design the tooling and automation that keep quality signals trustworthy, integrate them into CI/CD, and make it easy for engineers and QA vendor technicians to execute reliable, repeatable workflows. We’re looking for engineers with deep experience in software quality, automation, developer tooling, and hardware-software integration who thrive on building scalable, reliable systems for validation and release readiness. This role is based in San Francisco, CA. We use a hybrid work model of four days in the office per week and offer relocation assistance to new employees. In this role, you will: Test infrastructure & frameworks: Design, implement, and maintain a unified test framework for device software across unit, integration, system, and end-to-end testing, with reproducible runs and integrations with GitHub, Linear, and Slack. CI/CD integration & releases: Integrate test suites with Buildkite, enforce promotion criteria for staging and production, auto-file regressions, and publish traceable artifacts and release notes. Hardware-in-the-loop lab design & orchestration: Plan and bring up racks, power and networking systems, and orchestration for device testing; support automated flashing, provisioning

PythonAWSCI/CDGit
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Safety Systems team is dedicated to ensuring the safety, robustness, and reliability of AI models and their deployment in the real world. Learn more about OpenAI’s approach to safety. Building on the many years of our practical alignment work and applied safety efforts, Safety Systems addresses emerging safety issues and develops new fundamental solutions to enable the safe deployment of our most advanced models and future AGI, to make AI that is beneficial and trustworthy. About the Role At OpenAI, we're dedicated to advancing artificial intelligence, and we know that creating a secure and reliable platform is vital to our mission. That's why we're seeking a software engineer to help us build out our trust and safety capabilities. In this role, you'll work with our entire engineering team to design and implement systems that detect and prevent abuse, promote user safety, and reduce risk across our platform. You'll be at the forefront of our efforts to ensure that the immense potential of AI is harnessed in a responsible and sustainable manner. Your Responsibilities: Architect, build, and maintain anti-abuse and content moderation infrastructure designed to protect us and end users from unwanted behavior. Work closely with our other engineers and researchers to utilize both industry standard and novel AI techniques to measure, monitor and improve AI models’ alignment to human values. . Diagnose and remediate active incidents on the platform and build new tooling and infrastructure that address the root causes of system failure. You might thrive in this role if: You have built and run production services in a high growth, rapidly scaling environment. You can debug live issues and restore systems quickly. You have worked on content safety, fraud, or abuse, or are motivated and excited to work on present-day (“now-term”) AI safety. You have experience with Python or with modern languages such as C++, Rust, or Go, and are able to quickly ramp up on Py

PythonAWSAzureKubernetes
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

Job Description: Data Scientist, B2B Demand Generation, Growth & Measurement About the Role We are hiring a Data Scientist to lead measurement, experimentation, and decision science for B2B marketing demand generation. You will help us understand which marketing investments create incremental demand, qualified pipeline, and revenue and how to scale them efficiently. Our mandate is to build a rigorous, full-funnel view of how B2B marketing creates demand and moves prospects from awareness and engagement to qualified opportunities, closed-won revenue, and expansion. You will shape how we measure marketing impact and influence across channels, campaigns, audiences, and account segments. In this role, you will partner closely with B2B Marketing, Demand Generation, Growth, Sales, RevOps, Finance to connect marketing activity to qualified pipeline, customer acquisition, and efficient revenue growth. What You’ll Do Define north-star, leading, and guardrail metrics for B2B demand generation, including account engagement, qualified leads and opportunities, sourced and influenced pipeline, conversion rates, pipeline velocity, and incremental ARR. Design and execute measurement and experimentation strategies across channels and campaigns, using randomized tests, audience or geographic holdouts, lift studies, quasi-experimental methods, and other causal approaches suited to long B2B sales cycles. Analyze channel, audience, campaign, creative, content, landing-page, and account-segment performance to identify the drivers of qualified demand, funnel conversion, pipeline quality, and incremental revenue. Partner with Marketing, Sales, RevOps, Finance, Product, and Engineering to improve instrumentation, campaign taxonomy, CRM data quality, lead-to-account matching, and the operating cadence for acting on measurement insights. Build AI-native measurement and decision-support workflows, using LLMs and agents to synthesize campaign performance, surface growth opportunities, and h

PythonSQLAWSRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Software Engineering team is responsible for designing and building the scalable, performant, and secure backend systems that power our products—from early prototypes to large-scale deployments. We collaborate closely with product, hardware, and full-stack teams to ensure our infrastructure enables fast iteration while setting a strong foundation for long-term growth. About the Role As a Backend Engineer , you will design and build services, APIs, and infrastructure that support evolving product needs. You’ll apply a deep understanding of backend systems and maintain enough end-to-end context—from hardware to cloud—to guide technical decisions that best serve the product and team. We’re looking for engineers who thrive in fast-paced, collaborative environments and care deeply about building robust systems that scale. This role is based in San Francisco, CA . We use a hybrid work model of four days in the office per week and offer relocation assistance to new employees. In this role, you will: Architect, build, and maintain high-performance, secure backend systems. Design APIs, data models, and infrastructure to support evolving product needs. Balance near-term development velocity with long-term maintainability and scalability. Collaborate with cross-functional teams to ensure cohesive, end-to-end solutions. You might thrive in this role if you: Have 7+ years of professional software engineering experience, with a focus on backend systems. Have a proven track record of building and scaling systems from early stage to large scale. Are proficient with Python and Go, and familiar with a range of server-side technologies. Have a strong grasp of system design, performance optimization, and security best practices. Can reason about full-stack tradeoffs from hardware through cloud infrastructure. (Nice to have) Have experience with distributed systems and cloud architectures. (Nice to have) Bring a background in instrumentation, analytics, and performanc

PythonAWSRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team Security is at the foundation of OpenAI’s mission to ensure that artificial general intelligence benefits all of humanity. The Security team protects OpenAI’s technology, people, and products. We are technical in what we build but are operational in how we do our work, and are committed to supporting all products and research at OpenAI. Our Security team tenets include: prioritizing for impact, enabling researchers, preparing for future transformative technologies, and engaging a robust security culture. About the Role As a Security Engineer you will join our OpenAI engineers and researchers in building, operating and securing transformational AI technologies. This role will focus on all aspects of Detection & Response but with a strong emphasis on detecting insider threats and influencing controls to safeguard OpenAI's most sensitive assets. In this role, you will: In this role, you will: Innovate on Detection and Response infrastructure to engineer and automate end-to-end detection and investigation workflows. Develop, measure, and tune detection rules to ensure effective and sustainable operations. Drive projects across OpenAI’s technology stack with a focus on insider threats, ranging from access abuse and intellectual property theft to novel risks emerging within AI infrastructure. Partner closely with cross-functional stakeholders, including HR, Legal, and peer investigative teams, providing technical expertise and evidence to support investigations. Collaborate on cutting-edge AI research, and use AI to improve OpenAI’s Security posture. You might thrive in this role if you: 5+ years experience working in a detection/response or insider-risk role.. We are seeking mid-level and senior candidates. You have broad familiarity with operating systems and platforms such as macOS, Windows, Linux, and Kubernetes, along with experience in cloud infrastructure. Knowledge of modern adversary tactics and attack paths, data exfiltration techniques, and h

PythonAWSKubernetesLinux
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s User Operations team shepherds our customers’ adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others, to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. About the Role We’re looking for dedicated, experienced, and deeply curious individuals to help solve some of the most complex challenges faced by our customers while building the future of post-AGI support alongside us. In this role, you’ll work directly with customers through support tickets and live calls, troubleshooting high-impact issues and resolving novel, often ambiguous technical problems in one of the fastest-moving environments in technology. As AI adoption rapidly accelerates, the work you do will directly support mission-critical systems being built on OpenAI’s platform, serving as a critical line of defense for customers operating at massive scale. Beyond resolving technical issues, you’ll help define what world-class support looks like in an AGI-driven future. You’ll partner closely with Engineering, Product, and Operations to improve systems, reduce bugs, and elevate the customer experience, while leveraging automation, agents, and our own AI technology to transform how support operates at scale. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. As employees in this role with work with many customers based on the East Coast, regularly weekday hours will commence at 6am Pacific. To comply with a U.S. government contract, applicants for this position must be U.

PythonAWSRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s Hardware organization develops AI-native silicon and system-level solutions for the unique demands of advanced AI workloads. Building on efforts like Jalapeño, the team is developing future generations of AI-native silicon and tightly integrated systems to power the next generation of frontier models. By co-designing chips, systems, tools, and methodologies, the team helps deliver faster, more efficient, and production-ready hardware for OpenAI’s supercomputing platform. About the Role You will develop and evolve the tooling ecosystem that hardware engineers rely on every day — from hardware compilers and IR transformations to simulation, debugging, and automation infrastructure. The work spans software engineering, compiler concepts, and practical hardware workflows, with direct impact on how quickly and effectively we design next-generation AI systems. You’ll collaborate closely with architects, RTL designers, and verification engineers to translate real engineering friction into durable, scalable tooling solutions. In this role you will: Build and improve the software tooling that makes hardware teams faster: compilation, IR transforms, RTL generation, simulation, debug, and automation. Extend and integrate hardware compiler stacks (frontends, IR passes, lowering, scheduling, codegen to Verilog/SystemVerilog) and connect them to real design workflows. Improve developer experience and reliability: reproducible builds, better error messages, faster iteration loops, and dependable CI and regression infrastructure. Work closely with designers and verification engineers to turn real pain points into durable tools. Dive into RTL when needed: read and reason about Verilog/SystemVerilog to debug issues, validate tool output, and improve debuggability. Be willing to go all the way down the stack when necessary, including gate-level views, synthesis results, and implementation artifacts. Help enable PPA optimization loops by building analysis and au

PythonAWSGitRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s Hardware organization develops silicon and system-level solutions designed for the unique demands of advanced AI workloads. The team is responsible for building the next generation of AI-native silicon while working closely with software and research partners to co-design hardware tightly integrated with AI models. In addition to delivering production-grade silicon for OpenAI’s supercomputing infrastructure, the team also creates custom design tools and methodologies that accelerate innovation and enable hardware optimized specifically for AI. About the Role As an Engineer on our hardware optimization and co-design team, you will co-design future hardware from different vendors for programmability and performance. You will work with our kernel, compiler and machine learning engineers to understand their unique needs related to ML techniques, algorithms, numerical approximations, programming expressivity, and compiler optimizations. You will evangelize these constraints with various vendors to develop and influence future hardware architectures towards efficient training and inference on our models. If you are excited about efficiently distributing a large language model across devices, dealing with and optimizing system-wide/rack-wide networking bottlenecks and eventually tailoring the compute pipe and memory hierarchy of the hardware platform, simulating workloads at different abstractions and working closely with our partners, this is the perfect opportunity! This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. Key Responsibilities Co-design future hardware for programmability and performance with our hardware vendors Assist hardware vendors in developing optimal kernels and add support for it in our compiler Develop performance estimates for critical kernels for different hardware configurations and drive decisions on compute core and memory h

PythonAWSRestMachine Learning
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Preparedness team is an important part of the Safety Systems org at OpenAI, and is guided by OpenAI’s Preparedness Framework . Frontier AI models have the potential to benefit all of humanity, but also pose increasingly severe risks. To ensure that AI promotes positive change, the Preparedness team helps us prepare for the development of increasingly capable frontier AI models. This team is tasked with identifying, tracking, and preparing for catastrophic risks related to frontier AI models. The mission of the Preparedness team is to: Closely monitor and predict the evolving capabilities of frontier AI systems, with an eye towards misuse risks whose impact could be catastrophic to our society Ensure we have concrete procedures, infrastructure and partnerships to mitigate these risks and to safely handle the development of powerful AI systems Preparedness tightly connects capability assessment, evaluations, and internal red teaming, and mitigations for frontier models, as well as overall coordination on AGI preparedness. This is fast paced, exciting work that has far reaching importance for the company and for society. About the Role We’re hiring a Data Scientist to help build, evaluate, and continuously improve mitigations that prevent extreme harms from AI systems. This role is for an experienced, highly autonomous individual contributor who can take ambiguous problem statements, structure rigorous analyses, and translate findings into actionable product and policy changes. This position goes beyond “running evals.” You’ll help create mitigation intelligence and monitoring systems that enable OpenAI to detect issues early, measure effectiveness over time, and reduce both over-blocking (unnecessary friction) and under-blocking (missed harm). What You’ll Do Evaluate and improve mitigation systems, including classifiers and detection pipelines across domains (e.g., biosecurity, cybersecurity, and emerging risk areas). Diagnose false positives and fa

PythonSQLAWSRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s Hardware organization develops AI-native silicon and system-level solutions for the unique demands of advanced AI workloads. Building on efforts like Jalapeño, the team is developing future generations of AI-native silicon and tightly integrated systems to power the next generation of frontier models. By co-designing chips, systems, tools, and methodologies, the team helps deliver faster, more efficient, and production-ready hardware for OpenAI’s supercomputing platform. Role summary We are seeking a Networking Operating System Firmware Engineer to help bootstrap and scale the switching layer of our AI supercomputers. In this role, you will build and maintain custom NOS images from scratch, using open source components from SONiC, SAI, FRR, and related networking stacks while working across the Linux kernel, switch ASIC SAI/SDKs, platform drivers, control-plane services, and orchestration layers. This is a software engineering role that requires a deep understanding of networking, NOS internals, switch hardware, and production systems. You will design, implement, test, and debug production NOS software across platform drivers, routing and control-plane state, ASIC programming, observability, and fleet integration. The engineer in this role should be able to work through ambiguous, open-ended technical problems and drive feature development across software, hardware, and vendor boundaries. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will Design, develop, and maintain custom NOS images for large-scale AI fabrics, using open source components from SONiC, FRR, and related networking stacks. Integrate, build and configure Linux kernel components, device drivers, switch ASIC SDKs, and SAI layers. Bring up new switch platforms, including thermal and fan control, power monitoring, transceiver management, watchdogs, OSFP CMIS, L

PythonAWSCI/CDLinux
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Release Engineer team is responsible for building and maintaining the systems that power software delivery—from CI/CD pipelines and artifact management to release automation and fleet telemetry. We ensure software across bootloaders, firmware, operating systems, and cloud services is built reproducibly, validated rigorously, and released safely at scale. About the Role As a Release Engineer, you’ll design, build, and operate release infrastructure that enables reliable, secure, and traceable software delivery across complex multi-component systems. You’ll partner closely with embedded, cloud, and QA teams to ensure that every build—from development to OTA deployment—is fast, verifiable, and production-ready. We’re looking for engineers who take pride in automation, build reproducibility, and system reliability—and who enjoy building the connective tissue that allows hardware and software to ship together seamlessly. This role is based in San Francisco, CA. We use a hybrid work model of four days in the office per week and offer relocation assistance to new employees. In this role, you will: Design and operate CI/CD pipelines for multi-component builds (bootloader, firmware, OS images, backend, companion apps) using hermetic toolchains. Define versioning and branching strategies; automate promotions, changelogs, and artifact retention. Integrate unit, integration, and hardware-in-the-loop (HIL) test results; quarantine flaky tests, auto-bisect failures, and block unsafe promotions. Build A/B OTA update flows with verity and health checks; run staged rollouts and canaries; implement safe rollback and roll-forward strategies. Implement code signing for binaries and firmware, generate SBOMs, run vulnerability scanning, and attach build attestations and provenance. Manage dashboards and alerts for build health, promotion latency, failure rates, and fleet update telemetry. You might thrive in this role if you: Have experience building and operating buil

PythonAWSCI/CDGit
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s User Operations team shepherds our customers’ adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others, to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. About the Role We’re looking for dedicated, experienced, and deeply curious individuals to help solve some of the most complex challenges faced by our customers while building the future of post-AGI support alongside us. In this role, you’ll work directly with customers through support tickets and live calls, troubleshooting high-impact issues and resolving novel, often ambiguous technical problems in one of the fastest-moving environments in technology. As AI adoption rapidly accelerates, the work you do will directly support mission-critical systems being built on OpenAI’s platform, serving as a critical line of defense for customers operating at massive scale. Beyond resolving technical issues, you’ll help define what world-class support looks like in an AGI-driven future. You’ll partner closely with Engineering, Product, and Operations to improve systems, reduce bugs, and elevate the customer experience, while leveraging automation, agents, and our own AI technology to transform how support operates at scale. You’ll be responsible for: Working directly with customers to troubleshoot and resolve their most complex technical issues, including API failures, integration challenges, authentication errors, and production incidents. Providing end-to-end ownership through debugging logs, analyzing system behavior, reproducing issues, and

PythonAWSRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team With Codex we’re building an AI software engineer. One that you can pair with, delegate to, or even ask to take on future tasks proactively. Our team is a fast-moving group within OpenAI, bringing together research, engineering, design, and product. We iteratively build the Codex agent harness and product to get the most out of the model, and we iteratively train the model to be great at complex software engineering tasks. The Codex team is responsible for building state-of-the-art AI systems that can write code, reason about software, and act as intelligent agents for developers and non-developers alike. We operate across research, engineering, product, and infrastructure; owning the full lifecycle of experimentation, deployment, and iteration on novel coding capabilities. Codex Enterprise builds the ecosystem building blocks, discovery surfaces, and enterprise capabilities that help Codex spread across developers, teams, and organizations worldwide. It is a cross-cutting team that works across the stack to build both delightful product experiences and fundamental platform capabilities. Its customers range from individual developers and small teams to large enterprises, and our mission is critical to achieving the vision of Codex as a proactive teammate. About the Role As we grow, we’re focused on turning Codex from a powerful individual tool into a production-grade teammate for entire organizations. You will work across internal OpenAI teams and external customers, from fast-moving startups to large enterprises, to make it possible to deploy, operate, and trust Codex in increasingly demanding real-world environments. As Codex’s consumer adoption accelerates, enterprise demand is growing just as quickly, and there is also increasing opportunity to expand Codex through ecosystem capabilities that unlock new workflows, integrations, and discovery. This team helps turn messy, real-world team requirements into robust, repeatable, and scalable product and

PythonAWSCI/CDRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s API Multicloud team is responsible for extending OpenAI’s API platform into strategic cloud environments, starting with AWS . The team’s mission is to distribute OpenAI’s API broadly and safely by enabling key API technologies in AWS-native environments, in close partnership with Amazon and internal teams across Codex, Research, Safety Systems, and Applied. The team is focused on bringing core developer and enterprise capabilities into cloud-native environments, including AWS-hosted Codex, model customization / post-training as a service, and new stateful runtime environments for agentic workloads. This work sits at the intersection of production ML systems, developer platforms, model behavior, and large-scale infrastructure. About the Role We’re hiring Machine Learning Engineers to build and improve the AI systems that help strategic partners adapt OpenAI models to important use cases in cloud-native environments. This role spans post-training workflows, evaluation, data pipelines, model behavior, and API/infrastructure integration. You’ll work at the boundary between partner needs and core ML systems: helping teams understand what is and isn’t working, diagnosing issues in training and evaluation workflows, and turning those learnings into improvements to the underlying platform. You should enjoy working with external technical partners, extracting the real goal from messy requests, and pushing back or reframing when the requested experiment is not the highest-leverage path. You’ll collaborate closely with Research, Applied, Safety Systems, infrastructure teams, and external technical partners to solve ambiguous model-performance problems. When you succeed, strategic partners and internal teams will be able to improve model behavior with confidence, driving measurable product improvements while the systems behind that work become more reliable, scalable, and effective over time. In this role, you will Partner with strategic customers and in

PythonAWSKubernetesRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Connectivity Software Engineering team is responsible for enabling seamless, secure, and high-performance wireless connectivity across OpenAI’s products. We design and optimize Bluetooth, BLE, Wi-Fi, and emerging wireless technologies to ensure robust device pairing, network performance, and interoperability. Our work spans kernel drivers, system services, and user-level tools, with a focus on real-world performance, scalability, and reliability. About the Role OpenAI is seeking a Connectivity Software Engineer to design, implement, and optimize wireless connectivity features across our product ecosystem. You’ll work at the intersection of systems software, wireless standards, and hardware integration—building robust pairing and provisioning flows, debugging low-level protocols, and driving performance under real-world RF constraints. You will also support certification, field interoperability, and fleet-scale connectivity infrastructure. This role is based in San Francisco, CA . We use a hybrid work model of 4 days in the office per week and offer relocation assistance to new employees. In this role, you will: Design, implement, and debug Bluetooth/BLE and Wi-Fi features across kernel drivers, BlueZ/wpa_supplicant/hostapd, and systemd/D-Bus services Deliver robust pairing, bonding, and provisioning flows (GATT/GAP, LE Audio/LC3, WPA3/802.1X, captive portals, NAN) Optimize link performance: throughput, latency, jitter, roaming, coexistence (BT↔Wi-Fi), and power modes (TWT, WoWLAN) Build reliable network management using NetworkManager/nmcli, nl80211/cfg80211/mac80211, DNS/DHCP/mDNS, P2P/SoftAP Instrument and analyze with packet captures and tooling (btmon/hcidump, Wireshark, iperf, eBPF/perf, spectrum sniffers) Drive interoperability and certification readiness (Bluetooth SIG, Wi-Fi Alliance) and resolve field issues with root-cause fixes Contribute to OTA-safe configuration, telemetry, and diagnostics for fleet-scale operation You might thrive in

PythonAWSLinuxRest
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