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Python in San Francisco

319 active opportunities · Updated October 2026

Explore current python jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -83.5%

From $1.2M/yr

Quick readStrong listing-quality and freshness signals

We are Datadog's in-house product experts. The technical solutions team enables Datadog's worldwide growth by educating potential clients and ensuring that existing customers are happy and successful. A Technical Account Manager (TAM) will continue to provide hands-on technical services to our largest customers by supporting, adopting and providing guidance over the comprehensive suite of products and features available at Datadog. A TAM is held in high regard as an expert and trusted advisor for how IT Operations translates to business value. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Advise on technical support and product adoption for customers in line with pre-sales, post-sales and the renewal processes Analyze customer’s IT Operations environment on a regular basis and provide recommendations that will maximize Datadog’s value. Be the customer’s advocate by knowing their goals and use cases then suggesting process changes, product adoption, configuration and additional features to meet their requirements Participate and prepare for Monthly and Quarterly Business Reviews with customers Collaborate with Datadog’s product management, engineering and technical services teams to help identify new features and products Continuously evolve best practice to technical product adoption and customer success Who You Are: Someone with a solid technical grounding and hands-on experience of IT Operations Confident in your hands on experience AWS, Azure or GCP Comfortable scripting languages like Python, Javascript, Ruby, Perl, Go, PHP, or Chef/Puppet etc. Skilled in using CI/CD tools e.g. Jenkins, Gitlab etc. Knowledgeable about Containerization tools e.g. Docker, Kubernetes or Rancher etc. Able to sit up to 4 hours, traveling to and from client sites A

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team Enterprise Verticals builds role-specific ChatGPT Work experiences for high-value enterprise workflows. We combine product engineering, plugins and skills, connectors, data, evaluations, and customer evidence to turn useful demos into reliable daily work. This opening sits within the Technology vertical inside Enterprise Verticals. The group focuses on repeatable workflows for people at technology companies, beginning with functions such as data and analytics, sales, and design, and carries the shared platform needs—tool integration, permissions, quality measurement, and safe rollout—across those experiences. We work closely with Design, Research, GTM, Security, and platform teams, as well as with customers and design partners. Success means that people can reach a trustworthy first result, understand what the system did, and keep using the workflow—not merely that a prototype exists. About the Role We are looking for an exceptionally experienced, hands-on full-stack engineer to define and build the next generation of AI-powered enterprise workflows. You will take on the hardest and most ambiguous problems in the Technology vertical: translating real customer needs into product direction, designing the systems behind the experience, and personally writing and shipping production-quality code across the stack. You will own the technical direction and end-to-end delivery of products spanning ChatGPT Work surfaces, backend services, plugins, connectors, enterprise data, permissions, and evaluations. You will make foundational architecture and product tradeoffs; establish patterns other engineers can build on; and hold these experiences to a high bar for reliability, security, observability, and customer value. This is an individual-contributor role for an engineer who leads through technical judgment, direct execution, and influence—not people management. You should be equally comfortable working directly with customers, setting direction with senior cro

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team OpenAI for Financial Services is part of OpenAI's Verticals organization, which focuses on accelerating the economy and knowledge work. We build AI products for financial institutions and the professionals who power them, from investment bankers and research analysts to investors and other financial services teams. We combine OpenAI's models, financial data, and enterprise knowledge to help professionals research companies, analyze markets, and produce high-quality work in the tools they use every day. We're a small, entrepreneurial team working closely with customers and partners across research, product, design, engineering, and go-to-market to bring new capabilities from idea to production. About the Role We're looking for full-stack engineers to build new, AI-native products on top of ChatGPT Work and Codex. This is zero-to-one work: you'll help define how financial professionals research, analyze, and make decisions alongside AI. You'll own the experience across the stack, work directly with customers to understand their workflows, and collaborate across OpenAI to turn new model capabilities into products that professionals can trust. Your work will shape how some of the world's largest financial institutions adopt AI and how financial knowledge work gets done. In this role, you will: Build a new financial services app within ChatGPT Work and Codex, creating intuitive AI-native experiences for company research, financial analysis, document review, and professional work products. Develop new product experiences around enterprise memory that learn from an organization's knowledge, workflows, and context, and adapt to how its teams work. Develop the APIs, services, and integrations required to connect user experiences with financial data providers, enterprise systems, and OpenAI's models. Work closely with product and design to turn ambiguous customer problems into polished, useful, and reliable products. Work directly with financial institutions to

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team OpenAI for Financial Services is part of OpenAI's Verticals organization, which focuses on accelerating the economy and knowledge work. We build AI products for financial institutions and the professionals who power them, from investment bankers and research analysts to investors and other financial services teams. We combine OpenAI's models, financial data, and enterprise knowledge to help professionals research companies, analyze markets, and produce high-quality work in the tools they use every day. We're a small, entrepreneurial team working closely with customers and partners across research, product, design, engineering, and go-to-market to bring new capabilities from idea to production. About the Role We're looking for backend engineers to build the systems that make advanced AI useful, reliable, and trustworthy in financial services. You'll build the data systems, agentic workflows, and enterprise integrations behind our products. You'll also help bring them into production at some of the world's largest financial institutions. This is a product-minded engineering role with significant ownership and zero-to-one building. You'll shape new products from the ground up, work directly with customers to understand their workflows, and collaborate across OpenAI to turn new model capabilities into products that professionals can trust with high-stakes work. In this role, you will: Design and build backend systems that power AI-native financial workflows across ChatGPT Work and Codex. Build infrastructure to ingest, index, retrieve, and serve financial data, company filings, market information, and firm-specific knowledge at scale. Develop integrations with financial data providers, enterprise knowledge systems, and customer environments, including the authentication, authorization, and entitlements required to use them securely. Build the systems that let models and agents use the right tools and data, preserve source provenance, and produce accurate,

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team Enterprise Verticals builds role-specific ChatGPT Work experiences for high-value enterprise workflows. We combine product engineering, plugins and skills, connectors, data, evaluations, and customer evidence to turn useful demos into reliable daily work. This opening sits within the Technology vertical inside Enterprise Verticals. The group focuses on repeatable workflows for people at technology companies, beginning with functions such as data and analytics, sales, and design, and carries the shared platform needs—tool integration, permissions, quality measurement, and safe rollout—across those experiences. We work closely with Design, Research, GTM, Security, and platform teams, as well as with customers and design partners. Success means that people can reach a trustworthy first result, understand what the system did, and keep using the workflow—not merely that a prototype exists. About the Role We are looking for a full-stack product engineer who can own ambiguous enterprise workflows end to end: understand a customer problem, shape the product, build across frontend and backend, work through platform dependencies, instrument quality, and learn quickly with design partners. You will build across ChatGPT Work surfaces, services, plugins, connectors, and data or permission boundaries when the experience requires it. You will make quality and rollout observable through evaluations, product and operational signals, and clear fallback or rollback paths. This is a product-engineering role for someone who can move between user problems and system details without losing ownership of either. The strongest candidates will be able to turn specific customer evidence into a generalizable product, explain scope and architecture tradeoffs, and carry a feature from an early prototype through a bounded production rollout. In this role, you will: Build and ship role-specific workflows across ChatGPT Work surfaces, services, plugins, and connectors. Turn customer a

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team API Enterprise Controls is part of the API Infrastructure organization and owns the platform capabilities that help developers, startups, and enterprises adopt the OpenAI API securely and confidently. We build the systems underneath our APIs and developer platform across authentication and identity, service accounts and key management, secure networking, compliance, auditability, observability, and operational controls. Our users are developers and teams running critical applications on OpenAI, and we partner closely with Product, go-to-market, security, and infrastructure teams to turn their most important needs into reliable, intuitive platform capabilities. About the Role We are looking for an exceptional backend software engineer to help define and ship the enterprise capabilities our API Platform needs to scale.; this is a product-engineering role grounded in deep backend systems. You will work across databases, streaming systems, request routing, authentication, and developer-facing APIs while bringing strong product judgment, developer empathy, and attention to the small details that make a platform easier to understand, trust, and operate. You will lead large cross-functional initiatives, work closely with Product and go-to-market teams, engage directly with sophisticated users, and carry ambiguous needs from discovery through design, launch, and iteration. In this role, you will: Own backend product capabilities end to end across authentication and identity, service accounts and key controls, secure networking, compliance, observability, and operational workflows. Partner with Product, go-to-market, security, infrastructure teams, and sophisticated customers to identify needs, shape the roadmap, and lead large cross-functional projects from design through launch. Design developer-facing APIs, system behavior, configuration, error handling, safe defaults, auditing, and notifications with exceptional care for the details that define a great dev

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

ABOUT THE TEAM Critical Harm Operations sits within User Safety & Risk Operations and builds enforcement systems for Frontier Risk and Material Harm that are accurate, fast, defensible, and built to scale. The Cyber vertical turns policy into reviewer standards, calibrated judgment, quality systems, escalation paths, and automation guardrails. ABOUT THE ROLE We are looking for a senior cybersecurity practitioner and operations strategist to raise the quality, scalability, and technical rigor of our Cyber Operations. You will combine hands-on cyber judgment with systems-level operating design: resolve the hardest dual-use questions, evolve SOPs, uplift reviewers and vendors, and build practical tools and automations. This is a senior IC role. Success is not primarily cases closed; it is durable improvement in the operating model and the reviewers who run it. IN THIS ROLE, YOU WILL: Drive the Cyber Operations operating model across domain priorities, SOPs, escalation paths, quality health, vendor capability, roadmap inputs and help inform trusted access strategies. Serve as the senior cyber expert for complex or high-risk decisions across ChatGPT, API, Codex, agents, and emerging product surfaces. Translate policy ambiguity, quality misses, appeals, and reviewer disagreement into clear decision rules, calibration examples, training, and tooling requirements. Build durable operating systems and quality loops: golden sets, holdouts, double-labeling, adjudication, error taxonomies, reviewer calibration, and automation evaluations. Raise FTE and BPO capability through onboarding, certification, coaching, recurring calibration, and vendor-performance partnership. Use quality, appeals, SLA, backlog, and disagreement signals to diagnose root causes and prioritize high-leverage fixes. Build hands-on solutions—SQL analyses, scripts, dashboards, LLM eval workflows, evidence enrichment, routing logic, and lightweight automations—that improve decision quality and reduce manua

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team API Agents builds the shared agent harness, tools, and infrastructure that turn OpenAI’s frontier models into systems that can reliably complete real work. We carry the capabilities behind Codex into a much broader set of products and workflows across software engineering, research, finance, healthcare, enterprise operations, and more. Our work spans search and connected context, computer use, memory, delegation and multi-agent coordination, and safe execution. Sitting at the intersection of Research, Codex, infrastructure, and applied product teams, we build reusable agent capabilities that compound across the ecosystem. About the Role We are looking for an experienced backend software engineer to build the core systems behind the next generation of agents. You will design reliable services and abstractions that help agents find the right context, use tools and computers, retain knowledge, coordinate over long-running workflows, and take action safely. The role combines deep backend and infrastructure work with strong product judgment, with opportunities to work across agent runtimes, orchestration, search, execution environments, identity and permissions, observability, and evaluations. This is software and systems engineering rather than model training: success comes from strong backend fundamentals, high agency, and the ability to turn fast-moving research capabilities into dependable production primitives. In this role, you will: Design, build, and operate the shared agent harness and backend infrastructure that power long-running, high-value workflows across OpenAI and third-party products. Build reusable capabilities across search and connected context, computer use, memory, tool execution, delegation, subagents, and multi-agent orchestration. Establish the foundations agents need to operate safely in production, including secure execution environments, identity and permissions, observability, evaluations, reliability, and cost and latency effi

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team We're building the foundation for a new kind of AI coworker: persistent agents that have their own environments, can meet people wherever they work, and continue making progress for as long as a task requires. Our goal is to help individuals, teams, and organizations delegate meaningful work to AI—not just ask questions or complete a single turn. Our work brings together product, agent, and infrastructure capabilities across OpenAI. Together, we are creating always-on virtual coworkers that can carry context across tasks, operate through the right tools and channels, and deliver reliable results in real workplace environments. About the Role We’re looking for a full stack product engineer to shape how people discover, direct, and collaborate with AI coworkers. You’ll own product experiences end to end, spending roughly equal time building intuitive frontend surfaces and the backend systems that make agentic workflows persistent, reliable, and useful. You’ll work at the intersection of product engineering, design, agent capabilities, and enterprise readiness—turning rapidly evolving model and platform capabilities into experiences customers can understand, trust, and use every day. In this role, you will: Design, build, and ship full stack product experiences that help people and teams delegate meaningful work to persistent AI coworkers. Create intuitive frontend interfaces for directing agents, reviewing their progress, understanding their actions, and collaborating on the work they produce. Build backend APIs, services, and data models that support persistent agent state, asynchronous execution, orchestration, and progress reporting. Develop workflows that help agents access relevant context, use tools, and collaborate with people across workplace surfaces and channels. Partner with product, design, research, and engineering teams to turn shared capabilities into cohesive products. Build trust into the product through clear user controls, understanda

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team API Multimodal builds the developer-facing products and infrastructure that bring OpenAI’s image, audio, and real-time model capabilities into the world. We are responsible for high-scale APIs for image generation, speech transcription, speech generation, and low-latency voice interactions. We partner closely with Research and Inference to bring frontier model capabilities to developers and use customer feedback to improve our models. About the Role As a software engineer on API Multimodal, you will build and operate the products and distributed systems behind OpenAI’s image, audio, and real-time APIs. You will work across model integration, API design, and production infrastructure to turn new research capabilities into reliable developer experiences. This hands-on role combines backend and systems depth with product judgment: you will own projects end to end, partner with Research, Inference, and Safety, and help make multimodal AI useful at scale. Model training experience is not required. In this role, you will: Design, build, and ship developer-facing APIs and backend services that serve frontier models. Architect low-latency streaming, request, session, and model integration systems that make complex multimodal interactions reliable and intuitive at scale. Work directly with Research to bring new model capabilities into production, shape the systems around them, and incorporate feedback from real-world developers and customers. Own the availability, latency, scalability, and cost efficiency of the services you build. Own projects from technical design and implementation through launch and ongoing iteration, while raising the team’s engineering standards. Your background might look something like: 7+ years of professional experience, excluding internships, in backend, infrastructure, platform, or product engineering roles. A track record of designing, building, and operating production backend services, developer-facing APIs, or distributed syste

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team OpenAI's mission is to ensure that AGI benefits all of humanity. The Business Systems team helps make that mission possible by building the internal products and platforms that allow OpenAI to operate with speed, reliability, and care. We build internal applications and workflows for Finance and Supply Chain. Our work spans product discovery, React and TypeScript interfaces, Python services and APIs, data models, workflow orchestration, enterprise integrations, and the systems that connect people to systems of record. We work directly with the people who use these products and care about correctness, permissions, auditability, and production reliability. Examples of our work include building an integration platform for supply chain integrations, integrations with Oracle Fusion and Zip, contract intelligence applied to B2B revenue recognition, and Temporal-based agentic workflows for credit checks, duplicate bank detection, and invoice triaging. We turn these efforts into reusable patterns that can support many workflows, rather than one-off automations. About the Role We are looking for Product Engineers to build internal applications end to end. This role spans product discovery, user experience, frontend, backend services, data models, workflow orchestration, and integrations with order management, fulfillment, and supply chain systems. You will take a problem from a first conversation with a Finance or Supply Chain partner through design, implementation, rollout, and production support. Strong candidates combine product judgment with engineering depth. You should be comfortable moving between a React interface, a Python API, a durable workflow, and an integration with an enterprise system. You should be able to ship a useful first version quickly while building the foundations for reuse, security, and long-term maintainability. Direct AI experience is helpful, but the core requirement is strong product engineering judgment and reliable execution. I

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team The Systems Integration team is responsible for building the infrastructure, tooling, and validation systems that ensure our device software our device software is reliable, testable, and ready to ship. We design and maintain build systems, CI pipelines, automated test frameworks, and hardware-in-the-loop labs to enable rapid, safe product launches. Our work spans build systems, developer tools, systems integration, and cross-team collaboration to ensure developers can build reliably and ship with confidence. About the Role We are looking for an engineer to help evolve OpenAI’s Consumer Products build and continuous integration systems for a fast-growing engineering organization. This role sits at the intersection of developer productivity, build systems, distributed infrastructure, software quality, and on-device software. You will work on the systems that determine how quickly and confident engineers can move: Bazel-bazed builds, Buildkite pipelines, test coverage, remote caching and execution, CI observability, and tooling that helps engineers understand and fix failures quickly. Our mission is to enable OpenAI to ship software running on consumer devices rapidly with a high bar for correctness, reliability, and safety. The best version of this work is invisible when it succeeds: builds are fast, tests are trusted, CI failures are understandable, and engineers can focus on shipping products instead of fighting infrastructure. This role is based in San Francisco, CA. We use a hybrid work model of four days in the office per week and offer relocation assistance to new employees. In This Role, You Will Own and evolve Bazel and yocto-based build and test workflows in a polyrepo environment Design and maintain Starlark rules, macros, toolchains, and integrations that make builds hermetic, reproducible, and easy for teams to adopt Improve CI performance and reliability across Buildkite pipelines, including queue time, build time, cache hit rates, retry b

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team With Codex we’re building an AI software engineer. One that you can pair with, delegate to, or even ask to take on future tasks proactively. Our team is a fast-moving group within OpenAI, bringing together research, engineering, design, and product. We iteratively build the Codex agent harness and product to get the most out of the model, and we iteratively train the model to be great at complex software engineering tasks. The Codex team is responsible for building state-of-the-art AI systems that can write code, reason about software, and act as intelligent agents for developers and non-developers alike. We operate across research, engineering, product, and infrastructure; owning the full lifecycle of experimentation, deployment, and iteration on novel coding capabilities. Codex Enterprise builds the ecosystem, governance, and enterprise capabilities that help Codex spread across developers, teams, and organizations worldwide. The User Activation team owns the product experiences that help developers discover Codex, understand its capabilities, connect it to their workflows, and turn initial usage into sustained adoption across teams. About the Role As Codex adoption grows, our challenge is no longer just building powerful AI capabilities. It is helping developers and teams quickly understand how Codex fits into their work, connect it to the tools and codebases they already use, and unlock workflows that make Codex feel like a true teammate. This role will help build the full-stack product surfaces that drive activation and adoption across Codex Enterprise. You will work across onboarding, workspace setup, integrations, discovery, collaboration, usage insights, and ecosystem capabilities that help Codex spread naturally through organizations. You will partner closely with product, design, research, infrastructure, GTM, and customers to identify where users get stuck, where teams fail to adopt Codex, and what product experiences can turn curiosity int

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team ChatGPT is evolving from answering questions to becoming a deeply personalized assistant that helps people discover, create, and make decisions across everyday life. We're building new multimodal product experiences that combine language, images, personalization, and interactive interfaces to help millions of users accomplish tasks in entirely new ways. This team sits at the intersection of AI research, product engineering, design, and consumer experiences. We move quickly, ship frequently, and work on products that define how people interact with AI every day. About the Role We're looking for exceptional full stack product engineers who love building polished consumer experiences from the ground up. You'll work across frontend, backend, AI-powered workflows, and rich interactive interfaces to create new product experiences that blend conversation, visual understanding, personalization, and commerce. You'll collaborate closely with designers, researchers, product managers, and model teams to rapidly prototype, launch, and iterate on experiences used by millions of people. This is an opportunity to help invent entirely new interaction paradigms—not just build traditional web applications. In This Role, You Will Design and build end-to-end product experiences across web services, APIs, and modern frontend applications. Partner closely with product, design, and research to rapidly prototype and launch new AI-native experiences. Build intuitive, performant interfaces that make advanced AI capabilities feel simple and delightful. Develop scalable backend systems that power personalized, real-time product experiences. Work with multimodal capabilities including text, images, and interactive UI components. Iterate quickly using user feedback, experimentation, and product metrics. Help define engineering standards, architecture, and technical direction for a fast-growing product area. You Might Thrive If You Have significant experience building consumer-facin

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Team OpenAI’s API Multicloud team is responsible for extending OpenAI’s API platform into strategic cloud environments, starting with AWS . The team’s mission is to distribute OpenAI’s API broadly and safely by enabling key API technologies in cloud-native environments, in close partnership with Amazon and internal teams across Codex, Research, Safety Systems, and Applied. The team is focused on bringing core developer and enterprise capabilities into cloud-native environments, including cloud-hosted Codex, model customization / post-training as a service, and new stateful runtime environments for agentic workloads. This work sits at the intersection of production ML systems, developer platforms, model behavior, and large-scale infrastructure. About the Role We’re looking for a backend engineer who can quickly understand OpenAI’s models, products, and systems, then adapt first-party deployments for other cloud platforms. You’ll build backend services, APIs, SDK integrations, authentication flows, and cloud service infrastructure that let developers use OpenAI capabilities in the cloud environments where they already build. This role involves working across teams, sometimes embedded with partner product groups, to ship products quickly and across multiple platforms at the same time. It’s a strong fit for engineers who have built developer tools, especially AI-powered tools, communicate clearly across technical boundaries, and can shape architectures that support different deployment models; experience building cloud services is a strong plus. In this role, you will: Build backend and infrastructure systems that extend OpenAI’s API platform into cloud-native environments, like AWS. Design and ship cloud-contained products that allow customers to use OpenAI capabilities while keeping workloads and data within cloud environments. Help stand up cloud-hosted Codex experiences powered by the OpenAI Responses API. Build the infrastructure and runtime abstractions

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