Jobs in United States

Technical Program Manager 2c Knowledge Systems in United States

4,074 active opportunities · Updated October 2026

Explore current technical program manager 2c knowledge systems jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

Hiring demand

43/100

watch · 145 related jobs

Hiring trend

-65.7%

Job postings compared with the previous 30 days

Remote options

20.7%

Share of matching jobs listed as remote

Typical salary

$145.7K – $145.7K/yr

Based on 9 salary observations

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📍 New York, New York, United States· Full-time
✓ High-confidence listing

$95K – $140K/yr

Quick readStrong listing-quality and freshness signals

Lithic is the modern card issuing and processing platform empowering ambitious financial companies to build the future of payments. Our infrastructure powers card programs for 100+ innovative clients, from fintechs reimagining credit and digital banking to platforms transforming disbursements and spend management. Companies like Mercury, Flex, and Novo rely on Lithic's developer-friendly APIs, direct network connections, and flawless reconciliation to launch and scale card programs in weeks, not years. We're building a future where access to better financial products materially improves people's lives, free from the constraints of 30-year-old mainframes and legacy processors. We're proud to be backed by world-class investors who share that vision, including Bessemer Venture Partners, Index Ventures, Spark Capital, Stripes, and Mastercard, along with many others. We're a team of 170+ across 26 states and 7 countries, headquartered in New York City. We are seeking a Product Delivery Specialist to join Lithic’s team in our NYC office. In this role, you will lead complex customer implementations, drive operational excellence, and develop scalable processes that enable billions in transactions for the most innovative fintechs and digital banks. This position offers a unique vantage point across our business from product and engineering to compliance and operations allowing you to tackle meaningful challenges while making a tangible impact. In this role, you will coordinate a wide range of activities from implementing customer requirements and configuring the software to conducting technical setup and integration support with the ultimate goal of getting the customer’s solution live as quickly as possible, driving fast Time to Revenue (TTR) and provide great customer experience. You will operate at the intersection of our customers, internal teams, and third-party partners, executing progress across multiple project streams simultaneously. You will launch new

GitAIGoRust
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📍 State Of Missouri, United States of America, United States
✓ High-confidence listingCompany trend +1850%
Quick readStrong listing-quality and freshness signals

We anticipate the application window for this opening will close on - 30 Sep 2026 Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72&#43; million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact. A Day in the Life At Medtronic, we bring bold ideas forward with speed and decisiveness to put patients first in everything we do. This position is remote to enhance our competitive edge and expand our cross-functional collaboration efforts. This role will require 75% of travel to enhance collaboration and ensure successful completion of projects. In this exciting role as a Principal Field Clinical Specialist, you will provide day-to-day field clinical study support, technical and education support, and site management, coordination and training for the Mitral and Tricuspid Therapies clinical programs. This role will promote clinical programs through education of current and new investigators, new technologies and case support to achieve safe patient outcomes and company objectives . The M&T Structural Heart Business is one of the fastest growing businesses in the medical device industry and expanding rapidly to serve patients globally. The Structural Heart and Aortic integrated operating unit offers <

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📍 State Of Tennessee, United States of America, United States
✓ High-confidence listingCompany trend +1850%
Quick readStrong listing-quality and freshness signals

We anticipate the application window for this opening will close on - 30 Sep 2026 Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72&#43; million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact. A Day in the Life At Medtronic, we bring bold ideas forward with speed and decisiveness to put patients first in everything we do. This position is remote to enhance our competitive edge and expand our cross-functional collaboration efforts. This role will require 75% of travel to enhance collaboration and ensure successful completion of projects. In this exciting role as a Principal Field Clinical Specialist, you will provide day-to-day field clinical study support, technical and education support, and site management, coordination and training for the Mitral and Tricuspid Therapies clinical programs. This role will promote clinical programs through education of current and new investigators, new technologies and case support to achieve safe patient outcomes and company objectives . The M&T Structural Heart Business is one of the fastest growing businesses in the medical device industry and expanding rapidly to serve patients globally. The Structural Heart and Aortic integrated operating unit offers <

GCPExcelProject ManagementRecruitment
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -82%

About the Team The Privacy Engineering team builds the systems and technical foundations that govern how user data is understood, retained, accessed, and used across OpenAI. We partner with Product, Data, Infrastructure, Security, and Legal to translate policy and trust commitments into durable architecture and enforceable controls. Our work spans data inventory and mapping, classification and lineage, retention and deletion, access governance, purpose and usage controls, auditability, and lifecycle automation. We aim to make policy-aligned data handling the default while giving teams clear, reliable primitives for building and operating products at scale. About the Role We are looking for an experienced Software Engineer to drive the architecture and execution of user data governance across OpenAI. You will define technical direction, build shared platforms and controls, and lead cross-functional programs that make data flows discoverable, policies enforceable, and ownership explicit. This role is well suited to a senior engineer who can move between deep systems design and organization-wide influence, turn ambiguous requirements into pragmatic roadmaps, and operate high-trust systems end to end. This position is based in San Francisco. Relocation assistance is available. In this role, you will: Set the technical strategy and architecture for user data governance across data mapping, classification, lineage, retention, deletion, access, and permitted usage. Design and build shared services, APIs, metadata systems, and policy-enforcement mechanisms that make governance controls consistent, scalable, and auditable. Establish reliable inventories of user data, system ownership, data flows, and policy applicability across products, infrastructure, analytics, and research systems. Partner with Product, Data, Infrastructure, Security, and Legal leaders to define decision rights, translate requirements into controls, and drive adoption across teams. Own governance systems

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📍 Portage, Michigan, United States
✓ High-confidence listingCompany trend +364.7%
Quick readStrong listing-quality and freshness signals

Work Flexibility: Hybrid or Onsite Stryker is seeking a dynamic and visionary product development leader with a proven track record of leading large, complex product development programs through the application of systems engineering principles. As the technical quarterback, this individual will drive alignment, collaboration, and execution across a multidisciplinary global product line, ensuring teams work cohesively toward shared objectives while delivering innovative solutions that improve patient care. As medical technologies continue to evolve, our products must operate seamlessly within broader healthcare ecosystems and enabling technology platforms. This leader will be responsible for defining and overseeing system-level architectures, ensuring robust integration across hardware, software, data, connectivity, and partner technologies. They will champion a systems-thinking approach, proactively identify opportunities and risks, and ensuring our products deliver a seamless user experience while supporting the future needs of a connected healthcare environment. The ideal candidate combines deep technical expertise with exceptional leadership, influencing stakeholders across functions, geographies, and organizational levels to bring complex systems and product visions to life. https://www.stryker.com/us/en/nse.html What You Will Do Lead system architecture, technical strategy, and integration activities for complex medical device products and platforms. Translate customer, clinical, and business needs into system-level requirements and drive alignment across software, electrical, and mechanical engineering teams. Lead requirements development, allocation, traceability, and verification planning thro

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📍 Boston, Massachusetts, United States· Remote
✓ Quality checkedCompany trend -85.2%

As a Staff Application Security Engineer at Datadog, you'll set technical direction for how we approach application security at scale. You'll define the frameworks, methodologies, and architectural patterns that engineering teams across Datadog adopt and apply independently. You're the person others come to when they don't know how to make something secure, and you reliably have an answer. You'll be a point of contact for our most complex security programs, often spanning multiple teams and multiple quarters. The role requires both depth (going very deep on specific problems when needed) and breadth (recognizing patterns across systems and drawing connections that others miss). Partnering closely with teams inside and outside the security org is key to success. You'll help shape the AppSec roadmap and make the case for where investment should go. We use our own platform. Logs, Dashboards, Service Catalog, and APM aren't just things we sell: they're tools the AppSec team uses to build security services, measure adoption of secure defaults, and communicate risk across the organization. AI is also part of the picture. Engineering at Datadog increasingly uses agentic tooling throughout the development lifecycle, and many of the products we ship to customers now include AI-powered features. Both create new attack surfaces, and defining our strategy for addressing them is part of this role. If using Datadog to observe Datadog's own security posture, building impactful tooling, and shaping how we secure AI-powered systems sounds like the right kind of problem, this role is worth a close look. What You’ll Do: Define and drive security standards and secure-by-default solutions, serving as the Application Security subject matter expert. Build security tooling and automation that scales security practices across engineering teams, and implement robust security observability to support our threat detection team with meaningful, actionable security signals. Lead threat mod

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📍 Texas, United States of America, United States
✓ High-confidence listingCompany trend +103.7%
Quick readStrong listing-quality and freshness signals

Principal Data Privacy Architect Description - Job Summary - Role Purpose • Lead and oversee complex, cross-functional privacy and data protection programs from strategy through implementation, ensuring alignment across business, technical, legal, and compliance stakeholders. • This role will design and implement scalable, AI-ready data privacy architecture across enterprise data environments, applications, and AI-enabled workflows. • The Principal Data Privacy Architect will serve as a hands-on subject matter expert responsible for embedding privacy-by-design, consent enforcement, data sovereignty, data loss prevention, and compliance controls into large, complex global data environments. • The architect will partner closely with Data Engineering, Cybersecurity, Legal, Privacy, AI Governance, Product, and Enterprise Architecture teams to ensure customer, employee, partner, and sensitive enterprise data is accessed, processed, shared, retained, and protected in a compliant, secure, and trustworthy manner. - Why This Role Matters • Architect for Trust & Scale: Build reusable privacy architecture patterns that enable secure, compliant, and scalable data usage across platforms, products, and regions. • Enable Responsible AI: Design privacy guardrails for AI agents, generative AI, RAG pipelines, model inputs and outputs, embeddings, vector stores, and automated data workflows. • Reduce Risk While Enabling Innovation: Translate privacy, consent, regulatory, and data sovereignty obligations into practical engineering controls that accelerate business outcomes. Responsibilities - Think Customer First • Embed customer trust, transparency, and privacy-by-design principles into enterprise data platforms and customer-facing applications. • Design consent-aware data access and usage p

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📍 Grand Rapids, Michigan, United States
✓ High-confidence listingCompany trend +364.7%
Quick readStrong listing-quality and freshness signals

Work Flexibility: Field-based Position summary: Utilizes a wide array of knowledge, technical skills and critical thinking abilities to facilitate job functions during surgical procedures as well as preoperative and postoperative equipment management. ​ Essential Duties and Responsibilities: (detailed description) Provides clinical surgical support by managing all relevant equipment. Anticipates related device needs of the O.R. staff and surgeon during surgical procedures. Is responsible for trouble-shooting and maintaining Stryker equipment and or other related devices. Works with surgeons, O.R. personnel, central processing, biomedical and all other related personnel. Maintains knowledge base of equipment and disposable products through Stryker education training programs. Provide physicians and OR personnel with information on new and current products. Must be able to accurately and honestly record and report data metrics related to all specific job functions on a monthly basis. Responsible for maintaining up-to-date account information to ensure continuous high levels of service at the account; including all vendor credentialing required by the account. Accurately records and reports all surgical procedure information. Adheres to all Stryker and medical facility policies, standards and procedures. Analyze and resolve both routine and non-routine product issues expediently using independent judgment. Maintain professional appearance, work ethic, and attitude required by Stryker and the medical facility. Adhere to (HIPAA) and other related patient confidentiality policies and procedures. Provide support/coverage on all shifts at your assigned account, as well as provide support/coverage at other account in and outside your region; other sh

Supply Chain
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📍 California, United States
✓ High-confidence listingCompany trend +671.4%

$79.4K – $132.4K/yr

Quick readStrong listing-quality and freshness signals

Position Summary Pfizer is seeking a highly motivated Scientist to join the In Vivo Pharmacology group within the Oncology Research Unit, with a focus on antibody-drug conjugate (ADC) programs. This role supports the execution of high-quality in vivo efficacy, pharmacodynamic, tolerability, and mechanistic studies that enable preclinical ADC discovery and development. The ideal candidate will demonstrate strong technical capability in oncology animal models, careful attention to study details, and a commitment to animal welfare, compliance, and scientific rigor. The Scientist is expected to contribute as a reliable technical and scientific team member while developing increasing independence in study execution, data interpretation, and cross-functional collaboration. Position Responsibilities Execute in vivo oncology studies supporting ADC discovery programs using a variety of in vivo models including syngeneic, cell line-derived, and patient-derived xenograft models as appropriate. Perform routine and advanced in vivo procedures, including tumor measurements, body weight monitoring, test article administration, clinical observations, and sample collection. Support ADC pharmacology studies assessing efficacy, tolerability, pharmacodynamic biomarkers, dose-response relationships, schedule optimization, and combination strategies. Prepare, review, and follow study protocols, dosing schedules, randomization plans, and sample collection timelines in alignment with project goals and internal standards. Maintain accurate, timely, and compliant study records using electronic data capture systems and approved documentation practices. Coordinate with project line leads, vivarium operations, pathology, toxicology translational scientists, bioanalytical, pharmacodynamic and pharmacokinetic teams, and external partners to enable efficient study execution. Assist with data quality revie

AIRecruitment
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📍 New York, California, United States· Full-time
✓ High-confidence listingCompany trend -85.2%

From $220K/yr

Quick readStrong listing-quality and freshness signals

About the role: Datadog is building a product-led Competitive Intelligence function to help inform product strategy, roadmap prioritization, positioning, and competitive readiness. As the Head of Competitive Intelligence you will build and lead the CompIntel function across priority competitors and adjacent market opportunities. You will translate competitor product evolution, technical capabilities, launches, pricing value, customer sentiment, analyst narratives, and ecosystem shifts into actionable insights for Product, GTM, Sales Engineering, Customer Success, Technical Advocacy, and leadership. In this highly technical, hands-on leadership role, you should understand how observability products are implemented, where workflows differ, what technical claims are credible, and how product gaps translate into customer impact. What You'll Do: Own the recurring competitive radar for Datadog’s priority competitor set, including taxonomy, source standards, evidence quality, and update cadence. Produce competitive deep dives, feature-gap analyses, early-warning briefs, and opportunity assessments tied to specific product domains and leadership questions. Translate CompIntel findings into roadmap recommendations, product differentiation hypotheses, and Product-facing decision guidance. Build and maintain a central CompIntel repository with competitor profiles, source notes, comparison frameworks, evidence logs, and decision-ready briefs. Convert validated findings into GTM-ready handoffs for battlecards, objection handling, strategic deal narratives, and field enablement. Synthesize signals from Product, Engineering, Sales Engineering, Customer Success, field teams, technical communities, Advocacy programs, win/loss, customer feedback, analyst research, public competitor materials, and CABs. Partner with Product Management to frame competitive questions, identify decision criteria, and connect findings to roadmap and prioritization discussions. Partner with Tec

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -82%

About the Team The Enablement Lead (EL) team enables organizations to turn OpenAI products into real, sustained impact through world-class enablement and training execution. Our mission is to help customers successfully adopt and operationalize AI across their organizations. We partner with enterprises to translate the potential of OpenAI’s technology into durable capability—through structured training, technical enablement, and scalable deployment programs. By helping customers move from experimentation to production, the EL team accelerates time-to-value, deepens product adoption, and helps make OpenAI indispensable to how organizations work. About the Role The Enablement Lead, Builder role is a specialist post-sales technical enablement role focused on delivering high-impact enablement and adoption services across OpenAI’s product suite. You will design and deliver technical learning experiences covering OpenAI APIs, Codex, agents, evaluations, and related platform capabilities. You will work with engineers, AI and platform teams, administrators, security stakeholders, product leaders, and executive sponsors. This role blends deep technical fluency, instructional design, and customer advisory. You will lead live trainings, workshops, and adoption interventions for audiences ranging from hands-on builders to executive leaders, helping customers understand not just what OpenAI’s products can do, but how to use them effectively in real-world contexts. Success in this role means accelerating customer confidence, increasing product adoption, helping customers progress toward production use, and turning lessons from individual engagements into resources and practices that benefit many customers. This role is based in our San Francisco HQ. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Own the technical enablement of OpenAI products, including OpenAI APIs, Codex, Agents, Evaluations a

AWSRestAIGo
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -82%

About the Team Security is at the foundation of OpenAI’s mission to ensure that artificial general intelligence benefits all of humanity. The Security team protects OpenAI’s technology, people, and products. We are technical in what we build but are operational in how we do our work, and are committed to supporting all products and research at OpenAI. Our Security team tenets include: prioritizing for impact, enabling researchers, preparing for future transformative technologies, and engaging a robust security culture. About the Role OpenAI is seeking to build an investigative capability for Secure Manufacturing & Stealth programs. The risk surface for unreleased products, prototypes, confidential hardware, infrastructure, supply chain, manufacturing, and launch-readiness efforts spans employees, vendors, suppliers, logistics partners, physical movement of assets, procurement records, manufacturing workflows, access systems, device telemetry, and adversarial collection. This role is intended to build and run investigations across that specialized environment. In this role, you will: Lead complex SMS investigations to proactively identify and mitigate risks to unreleased products, prototypes, confidential hardware, secure manufacturing programs, and launch-readiness efforts. Investigate unauthorized disclosure, suspected leaks, insider risk, supplier compromise, vendor misconduct, theft, diversion, tampering, counterfeiting, surveillance, adversarial collection, and suspicious activity involving sensitive programs. Connect digital evidence, physical access activity, supply chain records, manufacturing data, vendor behavior, employee activity, collaboration metadata, procurement records, shipping data, and OSINT into clear findings and risk-reduction actions. Conduct proactive threat hunting to surface early indicators of compromise, collection, leakage, or insider activity affecting sensitive programs. Develop investigative playbooks, evidence-handling standards,

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📍 Washington, United States
✓ High-confidence listingCompany trend +671.4%

$68.6K – $114.3K/yr

Quick readStrong listing-quality and freshness signals

What You Will Achieve A Senior Associate Scientist (R2) position is available in the Conjugation Process Development group of Bioprocess R&D in USA - WA - Bothell. We’re seeking a passionate and creative individual to join a dynamic team of scientists and engineers focused on developing robust, scalable, and high productivity conjugation processes for the manufacture of antibody-drug conjugates (ADCs) for early- and late-phase clinical programs. The work will also involve working with commercial and clinical production facilities to ensure accurate technology transfer and successful large-scale production. You may also be involved in cutting-edge technology development projects that seek to discover new innovations for ADC process development and/or manufacturing. How You Will Achieve It Design, plan, and execute milligram to gram-scale conjugation experiments in the development laboratory. Ensures timely, effective, and high-quality documentation in electronic laboratory notebooks and internal technical reports. Communicate results and findings to stakeholders on a regular basis; present data/strategy to colleagues and management in internal and external venues (technical meetings, project team meetings, and conferences, etc.) as appropriate. Assist in or lead the technology transfer of manufacturing processes to clinical and commercial manufacturing facilities. Provide support and troubleshoot during manufacturing campaigns as needed. Work collaboratively with colleagues both within the group and cross-functionally; contribute to maintaining and improving upon our safe, effective and efficient lab operations. Qualifications Must-Have BS/BA in Chemistry, Biochemistry, Chemical/Biochemical Engineering, or other related disciplines with 3-4 years of experience, or MS in the above fields with 0-2 years of experience.

AIRecruitment
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📍 Long Beach, Canada
✓ High-confidence listingCompany trend +515.8%
Quick readStrong listing-quality and freshness signals

Software Chief Architect - AvionX Company: The Boeing Company The Boeing Company is looking for a Software Chief Architect - AvionX to join the AvionX Software team located in Long Beach, California . This position will focus on leading the AvionX Software Engineering organization. The Chief Software Architect for AvionX Software Vertical is the highest software technical authority across airborne software programs from architecture definition through certification closure. This role owns the coherence, integrity, and DO-178C/LOR compliance posture of software architectures across commercial and defense platforms, bridging software engineering discipline with system-level safety objectives and regulatory strategy. This role is also responsible to work with Enterprise Software Engineering Organizations to enable SW engineering practices and processes, such as Fabric, Design Practices etc. to be implemented across all AvionX Programs. Position Responsibilities: Advises management on a wide range of topics related to the embedded software engineering environment Consults on code for embedded systems software to run on specific specialized hardware Directs testing and debugging of software for embedded devices and systems. Influences current and emerging technologies, tools, frameworks, and changes in regulations relevant to software development and hardware technologies Directs the design, development, test, debugging and maintenance of software that is integrated into embedded devices and systems and meets industry, customer, safety and regulation standards Directs the review, analyses, and translation of customer requirements into the design of softwar

JavaLinuxC#Project Management
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📍 Hazelwood, United States
✓ High-confidence listingCompany trend +515.8%
Quick readStrong listing-quality and freshness signals

Senior Software Engineer - Vehicle Health Management Company: The Boeing Company The Boeing Company is looking for Senior Software Engineer – Vehicle Health Management to join our Government Vehicle Health Management Systems (GHVMS) software team in Hazelwood, MO . This position in the Boeing Global Services (BGS) organization will primarily support Boeing Defense, Space & Security (BDS) Air Dominance programs. The Senior Project Engineer will lead the full lifecycle of embedded software development integrated within specialized devices and systems, ensuring compliance with industry, customer, safety, and regulatory standards. This role directs the translation of complex customer requirements into effective software designs, overseeing code reviews, system integration, and improving software efficiency and stability on specialized hardware. Serving as a technical authority, the engineer guides testing, debugging, and the adoption of emerging technologies, tools, and regulatory changes to advance product performance. Additionally, the position leads the evaluation and coordination of internal and supplier teams, ensuring adherence to project plans and quality standards while providing strategic oversight of embedded software project management activities. In GVHMS, we develop software that enables maintainers to keep military aircraft mission-ready and safe. As a software engineer on our team, you will create solutions that monitor and predict the health of aircraft throughout their lifecycle. Your solutions will be used to enable smarter maintenance decisions, automate processes, and reduce costs. You will also have the opportunity to develop with emerging technologies, such as AI, to advance our software capabilities and drive the future of predictive

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