POSITION SUMMARY: Join Natera’s Oncology Research Use Only (RUO) team as a Supervisor for the Signatera Plasma Team. You will direct laboratory staff executing cell-free DNA (cfDNA) extraction, library preparation, and Next-Generation Sequencing (NGS) workflows to advance our personalized Minimal Residual Disease (MRD) assays. Every sample represents a real person, and you will ensure that all lab processes operate with the pace and precision required to support our clinical pipeline. PRIMARY RESPONSIBILITIES: Oversee the daily scheduling of employees executing DNA extractions, library preparation, Nucleic Acid Quality Control (QC), and NGS workflows Conduct regular 1:1 meetings to deliver unvarnished, data-backed performance evaluations and guide career development Take ownership of daily lab operations by directly executing sample processing alongside the team to maintain throughput Serve as the primary technical point of contact, using data to guide team members on data interpretation, next steps, and troubleshooting Execute process development and method/instrument testing to increase operational precision and scale Use data to identify lab process deviations, root-cause the underlying issues, and document findings via nonconformance reports to drive corrective action Draft, generate, and rigorously review Standard Operating Procedures (SOPs) and work instructions Maintain precise records of lab work using Google Sheets, Microsoft Excel, and internal Laboratory Information Management Systems (LIMS) Ensure accurate, ethical, and appropriate management of samples in strict compliance with all applicable federal regulations Think team by partnering directly with Oncology RUO peer groups to eliminate bottlenecks and optimize sample processing without needing translation layers Present data-backed summaries on team activities, project milestones, and timeline adherence Adapt to evolving science and operational needs, taking ownership of tasks that move th
Market pay estimate
$230,000–$319,023 / year for comparable Software Engineer roles in United States. Not employer-provided.
Role overview
Job description
POSITION LOCATION & DURATION: This is a six-month hybrid (one day a week onsite in San Carlos, CA) contract role with hourly compensation . There is potential to extend or convert to full-time based on performance and business needs. POSITION SUMMARY: As a Software Engineer, Full Stack you will design, develop, and maintain full-stack software applications, APIs, and data services that support our Sample Management and analytics platform. You have experience building user-facing web applications and have a passion for great user experience with a great eye for design. You're comfortable leveraging APIs and services, local and cloud-based, to deliver these experiences to users. You'll use these skills, along with tools like React, TypeScript, Python, FastAPI, Snowflake, dbt, AWS (ECS Fargate, Lambda, S3), and AWS CDK. Together with the talented Engineering Team, Product Managers and Desi
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What they are looking for
Skills & requirements
Qualification
5+ years of overall software development experience, preferably secure, scalable web applications with frontend and backend web technologies The following are specifically desirable: Experience with TypeScript Experience with Python and modern backend frameworks, especially FastAPI (with Pydantic and Uvicorn) Experience designing and building RESTful APIs Experience with React for frontend development, ideally with Material UI and Vite Experience with Docker, AWS ECS (Fargate), and infrastructure-as-code using AWS CDK Experience with cloud providers, AWS is preferred Experience with data warehousing and analytics, especially Snowflake and dbt Experience with databases including SQL (PostgreSQL, MySQL) and cloud data platforms Experience with micro-service enterprise architecture, cross-platform integration, and building scalable applications in heterogeneous environments Experience with the software development lifecycle process from build, software configuration, change control, and release and deployment activities Strong relational database skills including database design and optimization Demonstrated teamwork skills with a solid analytical background Excellent organizational
Department · Bio Development
Hiring company
Natera
Dedicated to oncology, women’s health, and organ health. Natera’s cell-free DNA tests help protect health and inform more personalized decisions about care.
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