Medical Director - Skin/IO

POSITION SUMMARY The Area Medical Director (AMD) is a senior physician leader embedded within a defined geography (Northeast, East, Central, or West) to serve as Natera's primary MD-to-MD clinical presence across the community oncology market. This role addresses the intersection of medical affairs, field execution, and scientific credibility — driving engagement with community oncologists, KOLs, and cross-functional field teams to accelerate appropriate utilization of Natera's oncology portfolio, including Signatera and Altera. The AMD owns regional medical strategy, leads cross-functional field partnerships, and operates with high autonomy to define and execute area priorities. The AMD functions without a defined playbook, translates business strategy into field-level action, and surfaces clinical intelligence that informs both commercial execution and development priorities. This is a 50% field-based role. PRIMARY RESPONSIBILITIES MD-Level Field Engagement ● Execute 12–18 MD-level engagements per quarter across defined geography, with at least 50% concentrated in top strategic community accounts. ● Maintain field presence of at least 4 ride days per month, prioritizing and overseeing area high-value and "platinum" accounts, including lost/down account retrieval. Responsible/accountable for oversight and coordination with these accounts with Associate AMD. ● Establish and maintain contact with the medical lead in the top 20 area accounts; engage 100% of flagged accounts within 10 business days. Cross-Functional Medical Leadership ● Serve as the primary MD triage point for escalated area medical inquiries, acknowledging at least 90% within 48 hours with 100% closed-loop documentation in Salesforce. ● Partner with MSL managers, Area Sales Directors, and Area Marketing Directors through structured bi-weekly and monthly cadences to align scientific messaging and commercial strategy. ● Participate in at least 75% o

POSITION SUMMARY The Associate Area Medical Director (Associate AMD) is a physician contributor operating within a defined regional geography under the guidance of an Area Medical Director or Medical Affairs leadership. This role is designed for a clinically credentialed oncologist who is building field medical affairs expertise and developing the cross-functional, commercial, and scientific capabilities required for full AMD-level autonomy. The Associate AMD executes field engagement activities, supports MSL partnership, and delivers scientific education within established frameworks and account priorities. The role contributes to insight generation and escalation management, but does not yet carry independent ownership of area strategy or cross-functional leadership. This is a 50% field-based role requiring strong clinical foundations, a bias for action, and the capacity to develop rapidly in a high-autonomy environment. PRIMARY RESPONSIBILITIES MD-Level Field Engagement ● Execute 8–12 MD-level engagements per quarter within defined geography, with at least 50% in pre-identified top strategic community accounts. ● Maintain at least 3 field ride days per month alongside MSL counterparts, targeting accounts designated by area leadership. ● Establish contact with medical leads in assigned top accounts; engage 100% of flagged accounts within 10 business days of assignment. Share responsibility for implementation and execution of “platinum-glove” provider engagement activities with area AMD lead. Scientific Communication and Education ● Attend, support, or present at regional educational programs as directed; develop toward independent program leadership over time. ● Complete annual recurrent speaker training; maintain working proficiency across assigned tumor histologies and the MRD diagnostic landscape. ● Document scientific exchange summaries and objection-handling themes in Salesforce following each engagement. &nbs

Advance patient care in gynecologic oncology as an Associate Medical Director at Natera. In this clinical leadership role, you will direct medical strategy and clinical development for our advanced cell-free DNA (cfDNA) and liquid biopsy portfolio, focusing on minimal residual disease (MRD) and recurrence monitoring for gynecologic malignancies (ovarian, endometrial, cervical, vulvar, and vaginal cancers). You will collaborate across research, development, commercial, and medical affairs teams to ensure the scientific rigor, clinical relevance, and clinical adoption of our molecular testing solutions. Primary Responsibilities: Clinical Development Partner with the Sr. Medical Director, Oncology on the clinical development of cell-free DNA (cfDNA) molecular diagnostics and liquid biopsy assays for gynecologic cancers. Direct the development and execution of clinical strategies and evidence-generation plans that demonstrate clinical utility in gynecologic oncology, including minimal residual disease (MRD) tracking, recurrence monitoring, treatment response assessment, and clinical trial enrichment. Medical Education and Communication Oversee medical education and scientific communications for healthcare providers focused on gynecologic oncology, including tumor boards, webinars, and field medical enablement. Partner with commercial and marketing teams to deliver clear, data-driven clinical evidence and educational materials to gynecologic oncology stakeholders, including gynecologic oncology surgeons, medical oncologists, pathologists, radiation oncologists, genetic counselors, and advanced practice providers. Representation and Advocacy Represent Natera at medical congresses and industry events, including SGO, ASCO, and ESMO, both in person and virtually. Build and maintain relationships with external experts, clinical investigators, cooperative groups such as NRG/GOG, and professional societies within gynecologic oncology. Maintain a standard of scientific rigor and

Director, Field Translational Science — Oncology Position Summary Natera is shifting disease management worldwide through unprecedented molecular innovation. As the Director of Field Translational Science, you will build, scale, and lead a specialized team of field-facing translational scientists within our Oncology Business Unit. This high-autonomy leadership role is designed for a strategic builder who can run a sophisticated regional team while serving as the executive authority for advanced Natera tests - including, but not limited to, cell-free DNA (cfDNA) and minimal residual disease (MRD) assays - and their associated data analysis frameworks across elite academic medical centers. This position requires up to 50-70% regional travel to engage with institutional leadership and audit high-priority research partnerships. You will eliminate the standard boundaries between field data generation and internal pipeline design. Distinct from traditional, education-focused Medical Affairs teams (MSLs), your organization owns the structural integrity, statistical validation, and scientific output of investigator-led data collaborations. Primary Responsibilities Team Leadership & Scale: Hire, develop, and manage a premier field organization of translational scientists, establishing clear performance metrics tied to regional data velocity, scientific rigor, and publication quality. Strategic Data Architecture: Author and execute the regional data engagement strategy, guiding how field scientists partner with oncologists, pathologists, and biometricians to unlock complex ctDNA and real-world datasets; holds the institutional/enterprise escalation line for the direct day-to-day communication line with the clinicians. Regional Operations & Systems Governance: Oversee the secure regional tracking architecture and data ingestion pipelines that individual Field Translational Scientists operate within; ensure absolute data compliance, system integrity,

POSITION SUMMARY: The Medical Science Liaison (MSL), Rare Disease is a field-based scientific expert and a key scientific resource for clinicians, academic institutions, and professional organizations in the Rare Disease community. This individual builds relationships with Key Opinion Leaders (KOLs), leads scientific exchange on Natera's Rare Disease test, and brings field insights back to Rare Disease leadership. The MSL works closely with the Rare Disease Sales, Marketing, and Medical teams to help bring the test to more patients. This role operates with a high degree of autonomy and reports to the Director of MSLs, Rare Disease. PRIMARY RESPONSIBILITIES: Provide scientific and clinical presentations on Natera products, with a focus on Rare Disease, and respond to customer requests for information about marketed and developing products. Develop, maintain, and manage relationships with KOLs from the Rare Disease community and other relevant healthcare professionals. Capture field insights on clinical practice, unmet needs, and market dynamics, and share them with Rare Disease leadership. Serve as a medical and scientific resource for the Natera Sales and Marketing teams, and collaborate with Marketing to develop educational materials for healthcare providers and patients. Participate in clinical research, data analysis, and scientific writing. Work with PHI in paper and electronic form. Complete HIPAA/PHI privacy, general policy and procedure compliance, and security training within the first 30 days of hire, and keep Natera training requirements current. Performs other duties as assigned. QUALIFICATIONS: Master's degree required, or a doctorate (PharmD, PhD, MD/DO, DNP), in a clinical or scientific field with relevant knowledge of Rare Disease. Prior experience as an MSL or in another field-based role highly preferred. Experience with the introduction of new clinical laboratory tests preferred. Must pass a post-offer criminal background check. KNOWLEDGE, SK

Position Summary We are seeking a strategic, analytical, and highly collaborative leader to serve as our Associate Director/Senior Manager of Health Economics & Outcomes Research (HEOR) Oncology. In this high-impact role, you will lead the development and execution of health economic and outcomes evidence demonstrating the clinical and economic value of Natera’s precision molecular diagnostic technologies across oncology and emerging indications. You will develop health economic models, generate real-world and clinical-trial evidence, lead HEOR publication initiatives, and translate complex clinical and economic data into compelling evidence supporting market access, reimbursement, payer adoption, clinical adoption, and commercialization. Working across Medical Affairs, Clinical Development, Biostatistics, Market Access, Commercial, Marketing, Regulatory, and Business Development, you will help integrate HEOR evidence throughout the product lifecycle—from clinical development and evidence generation through publication, reimbursement, and payer adoption. This is a strategic role for an experienced HEOR professional who combines strong technical capabilities with scientific communication, business acumen, and the ability to influence cross-functional evidence strategy. Why Join Us At Natera, you will have the opportunity to shape the economic evidence strategy supporting innovative precision diagnostics and biomarker-guided approaches to patient care. You will work at the intersection of clinical evidence, health economics, market access, and commercialization, translating clinical innovation into measurable value for patients, providers, health systems, and payers. You will collaborate with internal leaders, investigators, key opinion leaders, and external research partners to generate evidence capable of influencing reimbursement decisions, clinical adoption, health technology assessments, and healthcare policy across U.S. and global markets. Key Responsibiliti