Lead Machine Learning Scientist Jobs

We’re looking for a Staff Software Engineer with deep experience in GenAI/ML to join Datadog’s Application Performance Monitoring (APM) team. APM is a product which provides deep visibility into applications, enabling users to identify performance bottlenecks, troubleshoot issues, and optimize services. With distributed tracing, profiling, out-of-the-box dashboards, and seamless correlation with other telemetry data, Datadog APM provides some of the deepest and most structured visibility into the health and performance of applications. This context sets us up for an opportunity to be the world leaders in agentic investigations and incident troubleshooting. You’ll act as a technical leader within the APM group, focused on agentic workflows. You’ll lead efforts to design, train, evaluate, and deploy GenAI/ML models at scale. We’re looking for a product-minded ML engineer with strong technical expertise, excellent communication skills, and a track record of driving impactful initiatives end to end. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Act as a technical leader within the APM organization, driving GenAI/machine learning projects from concept to production. Build and benchmark GenAI/ML models using state-of-the-art techniques. Collaborate with cross-functional teams to build automated investigation and triaging tools. Influence product direction by bringing a strong product mindset to your work, always advocating for the end user. Guide teams through ambiguity, scaling challenges, and evolving requirements with clear technical direction. Actively mentor engineers and influence engineering culture through leadership in design reviews, technical talks, and working groups. Who You Are: You have a BS/MS/PhD in a scientific field or equiva

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. About the role We are looking for a threat intel manager to build and run our CBRN-E & Advanced Weapons team within Threat Intelligence. This team detects, investigates, and disrupts attempts to misuse Anthropic's AI systems for chemical, biological, radiological, nuclear, and explosives threats and for the development of advanced or novel weapons. You will mature this from a promising start into a rigorous program, hiring investigators with real CBRN-E, weaponization, and counterproliferation expertise, sharpening detection beyond broad harm screens into threat-specific capabilities, and personally leading the cases where scientific judgment determines whether we're seeing curiosity, legitimate research, or a genuine weapons-development attempt. The area carries significant engagement with government, biosecurity, and scientific stakeholders. Important context: In this position you may be exposed to explicit content spanning a range of topics, including those of a sexual, violent, or psychologically disturbing nature. This role may require responding to escalations during weekends and holidays. Key responsibilities Own strategy, priorities, and outcomes for the CBRN-E & Advanced Weapons mission area; mature it from an emerging function into a rigorous investigative program Hire, manage, and develop a team of investigators with deep domain expertise across biological, chemical, and weapons-development threat areas Personally lead investigations into attempts to use our systems to develop, enhance, or disseminate CBRN-E weapons, or advanced weapons capabilities Evolve detection from broad harm screens toward CBRN-specific signa

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, agitation associated with dementia due to Alzheimer’s disease, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, as well as multiple novel product candidates addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X . About This Role: Axsome Therapeutics is seeking an Associate Director, HEOR Analytics. This is a hands-on, technical role responsible for designing and executing real-world evidence (RWE) analyses using large-scale healthcare datasets, including administrative claims, electronic health records (EHR/EMR), and other real-world data sources. This role combines advanced statistical programming, study design, and analytical expertise to generate rigorous evidence supporting evidence generation priorities. The individual will lead the development of study protocols, statistical analysis plans, and study reports in partnership with the HEOR Lead & Medical Strategy colleagues, oversee programming and execution of analyses inclusive of quality control procedures, and deliver high-quality evidence to inform value demonstration, payer engagement, and scientific publications. This role is based at Axsome’s HQ in New York City with an on-site requireme

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. Anthropic is at the forefront of AI research, dedicated to developing safe, ethical, and powerful artificial intelligence. Our mission is to ensure that transformative AI systems are aligned with human interests. We are seeking a Research Engineer to join our Pretraining team, responsible for developing the next generation of large language models. In this role, you will work at the intersection of cutting-edge research and practical engineering, contributing to the development of safe, steerable, and trustworthy AI systems. Key Responsibilities: Conduct research and implement solutions in areas such as model architecture, algorithms, data processing, and optimizer development Independently lead small research projects while collaborating with team members on larger initiatives Design, run, and analyze scientific experiments to advance our understanding of large language models Optimize and scale our training infrastructure to improve efficiency and reliability Develop and improve dev tooling to enhance team productivity Contribute to the entire stack, from low-level optimizations to high-level model design Qualifications: Advanced degree (MS or PhD) in Computer Science, Machine Learning, or a related field Strong software engineering skills with a proven track record of building complex systems Expertise in Python and experience with deep learning frameworks (PyTorch preferred) Familiarity with large-scale machine learning, particularly in the context of language models Ability to balance research goals with practical engineering constraints Strong problem-solving skills and a results-oriented mindset Excellent communication skills a

Responsibilities: Annotate Case Report Form (acrf.pdf) following FDA/CDISC or sponsor guidelines. Develop SDTM specifications and generate SDTM datasets using SAS. Develop ADaM specifications and generate ADaM datasets using SAS based on Statistical Analysis Plan. Develop Tables, Listings, Graphs, Patient Profile in support of the Clinical Study Report, Posters, Manuscripts. Develop ADaM data, Tables, Listings, Figures for Integrated Summary of Safety (ISS) and Integrated Summary of Efficacy (ISE). Create electronic submission package to FDA, e.g., define.xml or define.pdf following FDA guidelines with minimum supervision. Proficient in analyze information and develop innovative solutions to programming and data analysis challenges; Support the point of contact (POC) of programming with statisticians for statistical input and analysis interpretation Follow and reinforce regulatory agency requirements during daily job. Serve as a programming team lead and contribute to department initiative. Provide guidance, mentoring, training for team members and help solve issues from cross-functional teams. Review draft and final production deliverables for project to ensure quality and consistency. Skills and Qualifications: Bachelor’s/Master’s degree in Statistics, Mathematics, Computer Science, Electrical Engineering, Biotechnology or related scientific disciplines. Minimum of 4+ years of clinical programming experience, along with 1+ year of project management and 1+ year of people management experience. Proven knowledge and training in high level computing languages such as. SAS, C/C++, Java, R, Python, MATLAB and SQL. Database programming experience is a plus. Proficient in decoding programming logic and assembling programming code based on logic provided and be able to explain to team members. Proficient in applying concepts in Artificial Intelligence and Machine Learning in the real world. In-depth knowledge of ICH, Good Clinical Practices, Clinical research, Clini

Responsibilities: Annotate Case Report Form (acrf.pdf) following FDA/CDISC or sponsor guidelines. Develop SDTM specifications and generate SDTM datasets using SAS; Develop ADaM,specifications and generate ADaM datasets using SAS based on Statistical Analysis Plan; Develop Tables, Listings, Graphs, Patient Profile in support of the Clinical Study Report, Posters, Manuscripts; Develop ADaM data, Tables, Listings, Figures for Integrated Summary of Safety (ISS) and Integrated Summary of Efficacy (ISE) Create electronic submission packages to FDA, e.g., define.xml or define.pdf following FDA guidelines with no supervision. Expert-level in analyze information and develop innovative solutions to programming and data analysis challenges; Serve as point of contact (POC) of programming with statisticians for statistical input and analysis interpretation; Follow and reinforce regulatory agency requirements during daily job. Serve as a programming team lead and contribute to department initiatives. Provide guidance, mentoring, training for team members and help solve issues from cross-functional teams; Review draft and final production deliverables for project to ensure quality and consistency. Work with global team or sponsors to coordinate project deliverables, timelines and resources. Skills and Responsibilities: Bachelor’s/Master’s degree in Statistics, Mathematics, Computer Science, Electrical Engineering, Biotechnology or related scientific disciplines with 5+years of clinical programming experience. Proven knowledge and training in high level computing languages such as. SAS, C/C++, Java, R, Python, MATLAB and SQL. Database programming experience is a plus. Expert-level in decoding programming logic and assembling programming code based on logic provided and be able to explain to team members. Expert level in applying concept in Artificial Intelligence and Machine Learning in real world. In-depth knowledge of ICH, Good Clinical Practices, Clinical research, Clinical tria

Who We Are Nuro believes self-driving vehicles are the most immediate and profound opportunity for AI to drive positive change in the physical world. Safer streets, more time for what matters, and easier access to the world around us, that’s why we’re building a universal autonomy platform: self-driving for all roads and all rides. Founded in 2016, Nuro is a physical AI company developing Level 4 autonomous driving technology for a wide range of vehicles, use cases, and markets. Powered by the Nuro Driver™, our universal autonomy platform enables the global mobility ecosystem to deploy autonomy at scale, from robotaxis and logistics fleets to personal vehicles. With years of real-world deployment experience and a flexible, partner-led business model, Nuro is working toward a future where millions of autonomous vehicles powered by our technology help make everyday life safer, easier, and more connected. Nuro has raised over $2B in capital from Uber, NVIDIA, Google, Softbank, Fidelity, T. Rowe Price, and other leading investors. About the Role We are looking for a Senior/Staff Machine Learning Engineer to be a technical leader on Nuro’s Behavior & Planning team. Our team owns how the Nuro Driver behaves on the road: prediction, decision making, and planning, and is responsible for turning Nuro’s large-scale driving data into safe, comfortable, and natural driving behavior. In this role you will bring strong, general machine learning expertise to some of the hardest problems in autonomy and drive them from research through to deployment on real vehicles. You’ll work at the frontier of applied ML spanning areas such as foundation and world models, LLM/VLM reasoning, reinforcement and imitation learning, generative and diffusion models, and transformer-based prediction and planning. You’ll apply this knowledge and experience to make our driving generalize as we scale across new geographies as we expand throughout the U.S. and globally, and across new vehi

Why Sony Interactive Entertainment? Sony Interactive Entertainment isn’t just the Best Place to Play — it’s also the Best Place to Work. Sony Interactive Entertainment (SIE) is the company behind the PlayStation brand. As a subsidiary of Sony Group Corporation, we’re part of a proud legacy of innovation and excellence. SIE is a dynamic technology company, delivering cutting-edge hardware and network services to more than 100 million people and an entertainment leader, home to some of the most beloved and recognizable intellectual properties (IP) in the world. Our role at SIE is to create and nurture the experiences under the PlayStation brand, a name synonymous with entertainment excellence and creativity. Role Description: We are looking for an independent, dedicated Lead or Senior Lead: Machine Learning to join the Visual Computing Group (VCG). This role contributes to redefining game play and live streaming through advanced R&D. VCG’s mission is to design and deploy advanced neural networks and machine learning (ML) for game rendering and streaming systems of SIE that exceed the state-of-the-art in runtime efficiency, visual quality and latency. Who Are You? You have a demonstrated ability in managing high performance research teams in the field of ML or Graphics You are a dynamic and visionary leader with a passion for building and leading high-performance teams. Your leadership style is grounded in clear communication, inspiration, and empathy. You possess the ability to motivate and empower your team, fostering an environment where creativity and collaboration thrive. A strong advocate for personal and professional growth, you ensure that every team member feels valued and heard. Your approach to leadership is proactive, adaptable, and driven by a deep commitment to the success of both your team and the organization. Experience in coaching and mentoring team members, fostering an inclusive and collaborative work environment. You have the coura

We offer a hybrid work environment. Most US-based positions can also be performed remotely (any exceptions will be noted in the Minimum Qualifications below.) Our Mission: To actively connect people to their next great opportunity. Who We Are: ZipRecruiter is a leading online employment marketplace. Powered by AI-driven smart matching technology, the company actively connects millions of all-sized businesses and job seekers through innovative mobile, web, and email services, as well as through partnerships with the best job boards on the web. ZipRecruiter has the #1 rated job search app on iOS & Android. About the Team: Jobs change lives - ask any one of our millions of job seekers we serve and you’ll no doubt get a similar answer. At ZipRecruiter, our products help connect job seekers with employers, eager to add talent to their company. Our team works on applications at scale, serving millions of job seekers. We’re building an innovative marketplace for both jobs and job seekers alike. As part of this effort, we’re hiring an Engineering Manager to lead our Machine Learning Engineering team. Our business is complex and we’re looking for engineering managers who can own entire (or even multiple) product lines, drive business value while investing in their team’s/tech stack’s health, and coach engineers to build a strong culture of excellence, ownership, and personal and professional growth. About the Job: Own the mission, execution, morale, and code quality of your team Partner effectively with product managers to maintain and execute against the product roadmap Serve as a force multiplier for your team by removing roadblocks, identifying and implementing process improvements, and delegating effectively Actively build community and culture throughout the engineering organization Continually develop, coach, motivate, and improve your team, leading by example Champion and evolve innovation at ZipRecruiter and evangelize BIG ideas Minimum Q

About Us Are you ready to build the future of supply chain? At Gather AI, we’re not just creating software; we’re pioneering a new era of warehouse intelligence. We’ve developed a groundbreaking, vision-powered platform that uses autonomous drones and existing equipment to capture real-time data, completely digitizing workflows that have historically been manual and error-prone. This means facilities operate smarter, safer, and more efficiently, ultimately redefining “on-time, in full” delivery. If you’re looking for an opportunity to contribute to truly transformative technology and make a significant impact in a vital industry, Gather AI is the place for you. We’re leading the charge in the rapidly evolving robotics industry, and we invite you to join us in reshaping the global supply chain, one intelligent warehouse at a time. About the Team You’ll lead the Machine Learning and FPT teams, working closely with the Director of Cloud Engineering and Director of Autonomy. Cross-departmentally, you’ll collaborate with Product and Business leadership to translate ML capabilities into product value. This is a high-visibility role with a direct line to executive leadership and significant influence over product direction. About the Role We are looking for a Director of Machine Learning to define our ML strategy, lead our computer vision organization, and drive the next phase of ML maturity at Gather AI. You will assess existing ML and CV capabilities, identify gaps and opportunities, and establish a clear technical vision for how machine learning will power our warehouse intelligence platform over the next 12–18 months. The ideal candidate brings deep computer vision expertise, a track record of shipping production ML systems, and the leadership experience to build and scale a world-class ML team. What You’ll Do Define and own the ML strategy and technical roadmap for Gather AI, aligned with product and business objectives Lead and grow the Machine Learning and FPT teams

We offer a hybrid work environment. Most US-based positions can also be performed remotely (any exceptions will be noted in the Minimum Qualifications below.) Our Mission: To actively connect people to their next great opportunity. Who We Are: ZipRecruiter is a leading online employment marketplace. Powered by AI-driven smart matching technology, the company actively connects millions of all-sized businesses and job seekers through innovative mobile, web, and email services, as well as through partnerships with the best job boards on the web. ZipRecruiter has the #1 rated job search app on iOS & Android. Summary: With data such as a billion+ historical job postings, tens of millions of active job seekers interacting with our system, and hundreds of billions of impression and click events, there are incredible opportunities to use your skills to build new data-driven features. Working at ZipRecruiter, you will be helping literally millions of people find their dream job. We’re working on problems like: given a training set of job postings, and known salaries, build a system that predicts salary for novel jobs.Of course, you know that while building models is fun, it's also just one step in the process; gathering training data, cleansing it, digging into it, extracting features from it, etc, is a huge part of the job Key Focuses: Design, develop, and maintain advanced machine learning models and algorithms to solve complex business problems Lead complex machine learning projects that solve business challenges and add value to the broader ZipRecruiter Business Design the overall architecture and infrastructure for machine learning systems, ensuring scalability, efficiency, and robustness Push the boundaries of what's possible in machine learning in your organization, finding new and innovative ways to use AI to drive business value Provide leadership and set tone for Machine Learning Engineers at ZipRecruiter leveraging industry best practices an

We offer a hybrid work environment. Most US-based positions can also be performed remotely (any exceptions will be noted in the Minimum Qualifications below.) Our Mission: To actively connect people to their next great opportunity. Who We Are: ZipRecruiter is a leading online employment marketplace. Powered by AI-driven smart matching technology, the company actively connects millions of all-sized businesses and job seekers through innovative mobile, web, and email services, as well as through partnerships with the best job boards on the web. ZipRecruiter has the #1 rated job search app on iOS & Android. Summary: With data such as a billion+ historical job postings, tens of millions of active job seekers interacting with our system, and hundreds of billions of impression and click events, there are incredible opportunities to use your skills to build new data-driven features. Working at ZipRecruiter, you will be helping literally millions of people find their dream job. We’re working on problems like: given a training set of job postings, and known salaries, build a system that predicts salary for novel jobs.Of course, you know that while building models is fun, it's also just one step in the process; gathering training data, cleansing it, digging into it, extracting features from it, etc, is a huge part of the job Key Focuses: Design, develop, and maintain advanced machine learning models and algorithms to solve complex business problems Lead complex machine learning projects that solve business challenges and add value to the broader ZipRecruiter Business Design the overall architecture and infrastructure for machine learning systems, ensuring scalability, efficiency, and robustness Push the boundaries of what's possible in machine learning in your organization, finding new and innovative ways to use AI to drive business value Provide leadership and set tone for Machine Learning Engineers at ZipRecruiter leveraging industry best practices an

We are hiring a Machine Learning Team Lead to lead a team of driven ML engineers working on translating cutting-edge research into ambitious, customer-centric speech solutions. As innovators in speech technology, our mission is to Understand Every Voice — a vision that has propelled us to be world leaders of Speech AI. Fuelled by innovation, inclusivity, and a passion for making a global impact through world-leading Speech AI, we're looking for an experienced Machine Learning Team Lead to accelerate our efforts towards exceptional speech solutions. Our Modelling Team builds and trains a broad spectrum of models, including large self-supervised architectures, advancing Speechmatics’ mission to provide the most accurate speech recognition technology worldwide. It also ensures their deployment into production, working with the latest developments in ML, but also with the best practices for software engineering and model serving. What you’ll be doing: Lead, mentor, and grow a world-class team of ML engineers through coaching and professional development Provide technical oversight and guidance for end-to-end ML development, ensuring solutions are robust and scalable Guide the adoption of best practices in software engineering Plan work, allocate resources and collaborate cross-functionally to align initiatives with business objectives and bring solutions to production Drive the technical work for the ML team to deliver high-quality technical solutions that achieve ambitious strategic goals Who we are looking for: Demonstrable experience in guiding and mentoring ML engineers Adept at prioritizing work by impact, feasibility, and time-to-value, with clear success metrics Strong understanding of the modern Machine Learning stack, for example: - Knowledge of contemporary transformer architectures, related concepts (e.g., GQA , KV -caching) and best practices - Expertise in distributed training techniques - Familiarity with optimisation strategies for m

We are hiring a Machine Learning Team Lead to lead a team of driven ML engineers working on translating cutting-edge research into ambitious, customer-centric speech solutions. As innovators in speech technology, our mission is to Understand Every Voice — a vision that has propelled us to be world leaders of Speech AI. Fuelled by innovation, inclusivity, and a passion for making a global impact through world-leading Speech AI, we're looking for an experienced Machine Learning Team Lead to accelerate our efforts towards exceptional speech solutions. Our Modelling Team builds and trains a broad spectrum of models, including large self-supervised architectures, advancing Speechmatics’ mission to provide the most accurate speech recognition technology worldwide. It also ensures their deployment into production, working with the latest developments in ML, but also with the best practices for software engineering and model serving. What you’ll be doing: Lead, mentor, and grow a world-class team of ML engineers through coaching and professional development Provide technical oversight and guidance for end-to-end ML development, ensuring solutions are robust and scalable Guide the adoption of best practices in software engineering Plan work, allocate resources and collaborate cross-functionally to align initiatives with business objectives and bring solutions to production Drive the technical work for the ML team to deliver high-quality technical solutions that achieve ambitious strategic goals Who we are looking for: Demonstrable experience in guiding and mentoring ML engineers Adept at prioritizing work by impact, feasibility, and time-to-value, with clear success metrics Strong understanding of the modern Machine Learning stack, for example: - Knowledge of contemporary transformer architectures, related concepts (e.g., GQA , KV -caching) and best practices - Expertise in distributed training techniques - Familiarity with optimisation strategies for m

About Ema Ema is building the world’s leading Agentic AI platform to transform enterprise productivity. We enable organizations to delegate repetitive tasks to Ema, the Universal AI Employee, delivering 10x gains in workforce efficiency, across functions. Founded by former executives from Google, Coinbase, Flipkart, and Okta, our team includes engineers from premier tech companies and graduates of Stanford, MIT, UC Berkeley, CMU, and IITs. We are backed by industry leading investors including Accel, Naspers/Prosus, Section32, and angels like Sheryl Sandberg and Dustin Moskovitz. Headquartered in Silicon Valley and with offices in London, Bangalore and Vancouver, Ema is at the frontier of what Agentic AI can do in production — we ship real systems that run real business processes at scale. Who you are We're looking for an innovative and passionate Machine Learning Engineers to join our team. You are someone who loves solving complex problems, enjoys the challenges of working with huge data sets, and has a knack for turning theoretical concepts into practical, scalable solutions. You are a strong team player but also thrive in autonomous environments where your ideas can make a significant impact. You love utilizing machine learning techniques to push the boundaries of what is possible within the realm of Natural Language Processing, Information Retrieval and related Machine Learning technologies. Most importantly, you are excited to be part of a mission-oriented high-growth startup that can create a lasting impact. You will: Conceptualize, develop, and deploy machine learning models that underpin our NLP, retrieval, ranking, reasoning, dialog and code-generation systems. Implement advanced machine learning algorithms, such as Transformer-based models, reinforcement learning, ensemble learning, and agent-based systems to continually improve the performance of our AI systems. Lead the processing and analysis of large, complex datasets (structured, semi-structured, and