Lead Safety Engineer Jobs

Natera’s Research team is building tests that can detect many cancers from a single blood draw. We are looking for a Staff Machine Learning and Bioinformatics Scientist to help design the models at the heart of that effort. You’ll work with large-scale, multi-modal genomic datasets from clinical cohorts and partner closely with molecular biologists and clinical scientists. Your research will advance the state-of-the-art and you will drive new methods from prototype, through scalable implementation, toward clinical validation and, ultimately, to patients. PRIMARY RESPONSIBILITIES: Lead the development of novel statistical and machine learning methods for cancer signal detection on multi-modal genomic data Build interpretable, well-calibrated models, setting the standard for uncertainty estimation and reproducibility across the group Prototype, test and productionize ML models using scalable infrastructure Own key technical deliverables within larger projects and help shape the team’s research roadmap Collaborate closely with molecular biologists and clinical experts on design and analysis of experiments and validation studies Keep raising the bar through code and design reviews across projects Translate complex results into clear stories for technical and non-technical audiences Mentor junior scientists and champion a culture of curiosity, collaboration, and scientific excellence QUALIFICATIONS: PhD in Computer Science, Mathematics, Bioinformatics, or a related quantitative field with 6-12 years of experience post-PhD Hands-on experience developing novel statistical / ML analysis methods applied to complex biological data Proven track record of innovation and technical leadership in complex method development projects Expertise in deep learning and multimodal foundation models Proficient in Python and its scientific computing ecosystem Scientific rigor throughout the R&D process, with eagerness to teach and learn new computational methods and biology Excellent co

Natera’s Research team is building tests that can detect many cancers from a single blood draw. We are looking for a Staff Machine Learning and Bioinformatics Scientist to help design the models at the heart of that effort. You’ll work with large-scale, multi-modal genomic datasets from clinical cohorts and partner closely with molecular biologists and clinical scientists. Your research will advance the state-of-the-art and you will drive new methods from prototype, through scalable implementation, toward clinical validation and, ultimately, to patients. PRIMARY RESPONSIBILITIES: Lead the development of novel statistical and machine learning methods for cancer signal detection on multi-modal genomic data Build interpretable, well-calibrated models, setting the standard for uncertainty estimation and reproducibility across the group Prototype, test and productionize ML models using scalable infrastructure Own key technical deliverables within larger projects and help shape the team’s research roadmap Collaborate closely with molecular biologists and clinical experts on design and analysis of experiments and validation studies Keep raising the bar through code and design reviews across projects Translate complex results into clear stories for technical and non-technical audiences Mentor junior scientists and champion a culture of curiosity, collaboration, and scientific excellence QUALIFICATIONS: PhD in Computer Science, Mathematics, Bioinformatics, or a related quantitative field with 6-12 years of experience post-PhD Hands-on experience developing novel statistical / ML analysis methods applied to complex biological data Proven track record of innovation and technical leadership in complex method development projects Expertise in deep learning and multimodal foundation models Proficient in Python and its scientific computing ecosystem Scientific rigor throughout the R&D process, with eagerness to teach and learn new computational methods and biology Excellent co

The Team + The Role Pendo’s Customer Engineering team is the technical backbone of the pre- and post-sales customer motion. The team brings together work across Customer Success, Technical Account Management, and Solutions Engineering into one full-lifecycle technical owner. Customer Engineering helps customers connect technical execution to business outcomes and realize the value of their investment in Pendo. As a Senior Customer Engineer you will own strategic and complex Enterprise accounts across acquisition, implementation, adoption, expansion, and escalation. You will lead technical strategy for complex deployments, resolve ambiguous customer challenges, and partner closely with account teams to drive retention, expansion, and customer value. Your impact will extend beyond your own accounts through playbooks, coaching, repeatable fixes, and workflow improvements that raise the capability of the broader Customer Engineering team. This role is based in our London office. What this looks like day-to-day New customer acquisition and selling: Partner with Account Directors on pre-sales motions for new customer acquisition, product expansion, and growth across lines of business. You identify customer pain, craft and deliver tailored demos, and lead technical evaluations through requirements gathering, success criteria, installation guidance, and hands-on workshops. Quarterly business outcomes: Drive measurable improvement in customer health, retention, expansion, and technical resolution across strategic accounts. You contribute at least one reusable framework, playbook, or process that other Customer Engineers use and become a trusted advisor to Account Directors on account health and technical strategy. Adoption, expansion, and growth: Identify opportunities to expand adoption across underutilized features, untapped products, and new lines of business. When adoption stalls, y

About the Organization Crypto.com is one of the world's leading cryptocurrency platforms, serving over 100 million customers globally. Through its acquisition of the North American Derivatives Exchange, Inc. (Nadex), Crypto.com operates a CFTC-regulated designated contract market (FCM/DCM) in the United States, offering derivatives and event contracts to U.S. participants. OG.com, the company's prediction markets platform, extends this regulated infrastructure to event-based trading, positioning the organization at the forefront of the rapidly evolving intersection of digital assets, derivatives, and prediction markets. The Opportunity We are seeking a CFO, North Americas to lead the financial function, with responsibility for managing all aspects of finance, audit, tax, accounting and treasury for our U.S. and Canadian entities. This executive will serve as the senior finance leader on the ground in North America, partnering closely with the Group CFO and global finance team while owning the regional financial architecture that supports a CFTC-regulated exchange, a crypto trading platform, a prediction markets business, new business lines, and a NY OCC Trust bank.. The ideal candidate brings a distinctive blend of financial services expertise, public accounting rigor, and hands-on experience in the digital asset industry. Key Responsibilities Strategic Finance & Leadership Own the financial strategy and long-range planning for all Americas entities, including Nadex (DCM), OG.com prediction markets operations, and the U.S. crypto exchange business. Serve as the primary finance business partner to Americas leadership, providing data-driven insights on revenue, margin, product economics, and capital allocation. Build and present board-ready financial narratives and investor materials as needed. Lead annual budgeting, quarterly forecasting,

The Team + The Role Pendo’s Customer Engineering team is the technical backbone of the pre- and post-sales customer motion. The team brings together work across Customer Success, Technical Account Management, and Solutions Engineering into one full-lifecycle technical owner. Customer Engineering helps customers connect technical execution to business outcomes and realize the value of their investment in Pendo. As a Senior Customer Engineer you will own strategic and complex Enterprise accounts across acquisition, implementation, adoption, expansion, and escalation. You will lead technical strategy for complex deployments, resolve ambiguous customer challenges, and partner closely with account teams to drive retention, expansion, and customer value. Your impact will extend beyond your own accounts through playbooks, coaching, repeatable fixes, and workflow improvements that raise the capability of the broader Customer Engineering team. This role is based in our London office. What this looks like day-to-day New customer acquisition and selling: Partner with Account Directors on pre-sales motions for new customer acquisition, product expansion, and growth across lines of business. You identify customer pain, craft and deliver tailored demos, and lead technical evaluations through requirements gathering, success criteria, installation guidance, and hands-on workshops. Quarterly business outcomes: Drive measurable improvement in customer health, retention, expansion, and technical resolution across strategic accounts. You contribute at least one reusable framework, playbook, or process that other Customer Engineers use and become a trusted advisor to Account Directors on account health and technical strategy. Adoption, expansion, and growth: Identify opportunities to expand adoption across underutilized features, untapped products, and new lines of business. When adoption stalls, y

About the Team The User Operations team (Support) is central to ensuring that our customers' experience with our products is nothing short of exceptional. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. About the Role We’re seeking a Program Manager to lead support readiness and operational programs for OpenAI’s cloud and strategic partnerships. You’ll work closely with Engineering, Product, Support Delivery, and external partners to translate complex technical and business requirements into scalable customer support experiences. This role will help define how we support customers across partner ecosystems, from launch planning and issue-routing workflows to escalation management and ongoing operational improvements. In this role, you will: Lead support readiness for new and existing cloud and strategic partnerships, including launch planning, operational design, and ongoing program execution. Partner closely with Engineering, Product, go-to-market teams, and external partners to develop support models for technically complex products and integrations. Define partner-specific customer journeys, support workflows, escalation paths, ownership models, and cross-company handoffs. Identify operational and technical risks, align stakeholders on solutions, and drive improvements that strengthen the customer experience. Establish clear success metrics and operating rhythms to monitor partnership health, launch readiness, and support performance. Use AI and automation to improve partner-related support workflows and scale operations effectively. You might thrive in this role if you: Have 8+ years of experience

As Head of Social for Square, you’ll sit within Brand Strategy & Marketing and own social as a channel: its strategy, audience, content calendar, community, and performance. This is an individual contributor role with no internal team; you’ll be the primary point of contact for social, partnering with the Brand Lead and your creative counterpart to connect Square’s positioning to the work that gets published. Your primary focus will be organic and owned content, with responsibility for advancing brand perception goals and partnering with paid teams so organic and paid reinforce each other. You Will Set the social strategy for Square. Define what social is for, what it does that other channels cannot, and what it is deliberately not for. Connect that strategy to Square’s positioning in partnership with the Brand Lead. Define the audience and measures of success. Identify who Square is talking to on social, what they care about, and where they spend time. Make that understanding the foundation of the strategy, and establish the channel’s key success metric and the rationale behind it. Build and own the social content calendar. Plan for major brand campaigns and moments alongside a consistent, always-on content program, showing how both support Square’s brand perception goals. Bring cross-team activity into social with intent. Work with partnerships, the Brand Lead, and other teams to identify what belongs on social and how it should show up. Be the primary point of contact for requests and make decisions about channel fit. Partner with paid social and media teams. Ensure organic and paid activity reinforce each other as part of a connected approach. Shape the role of creators and influencers. Identify where they can credibly support Square’s social strategy, audience, and campaign goals. Partner with Partnerships, Brand, Demand Generation, Legal, and agencies on recommendations, vetting, briefing, disclosure guidance, and performance readouts. Take content from id

At Ripple, we’re building a world where value moves like information does today. It’s big, it’s bold, and we’re already doing it. Through our crypto solutions for financial institutions, businesses, governments and developers, we are improving the global financial system and creating greater economic fairness and opportunity for more people, in more places around the world. And we get to do the best work of our career and grow our skills surrounded by colleagues who have our backs. If you’re ready to see your impact and unlock incredible career growth opportunities, join us, and build real world value. THE WORK: We seek a Senior Staff Product Manager to lead and develop our Trust Platform — the programmable controls, integrations, and tools that enable our products to function securely and reliably as we grow into more regulated, higher-risk markets such as banks and other regulated entities. You'll determine what features should be included in the platform and which ones become reusable components other teams can build upon. You will assess how the roadmap stands up to careful examination from regulators, bank diligence teams, and the product teams working on what you develop. You will work closely with Compliance, Legal, and Engineering, maintaining clear responsibility for the product roadmap and decisions. Why Now? The regulatory landscape is growing. More jurisdictions, more counterparties, more edge cases — this needs someone thinking ahead of requirements, crafting our posture before it's forced on us. Trust is a competitive advantage. Our strategy increasingly points at selling into banks and other regulated counterparties, who diligence maturity, auditability, and programmable controls as part of the buying decision. This work helps us secure agreements. The platform opportunity is genuine and ready to develop. We have reached a stage where this logic should become a configurable core element for other teams to build upon. It involves deciding what is

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. About the role AI is changing what security teams can do. Claude can find and help fix vulnerabilities in code at a pace that wasn't possible a year ago, and we want defenders to have that advantage first. As a Cybersecurity Sales Specialist, you'll own Anthropic's security business across the accounts in one of our business units, such as financial services, healthcare and life sciences, or technology. You'll lead the security strategy with CISOs, partnering with the Account Executives who own the accounts in your industry to drive opportunities and put Claude to work on their hardest security problems. You'll help decide how we sell security, what we learn from customers, and how that shapes our products. The work matters to our mission: a safe transition through transformative AI depends on the people who defend critical systems being able to use it well. Key responsibilities Build and close security business, from the first conversation with a CISO's team through contract and expansion, working with the Account Executive who owns each relationship Create security pipeline with the Account Executives in your industry, from their existing accounts and through outbound to security leaders, events and joint work with partners Lead with the customer's problem: finding and fixing vulnerabilities, application security, security operations, and deploying AI agents securely Partner with your Applied AI engineers on discovery, proofs of concept and architecture, and know when to bring them in Guide customers through security reviews, verification for security use cases, and procurement Teach the Account Executives in your business unit to s

At Affirm, we exist for the moments that matter—giving people a clear, predictable way to pay over time, with no hidden fees, no surprises, and no tradeoffs on what matters most. The Marketplace and App Experience domain is the main pillar of our core consumer strategy, driving the user journey across all of our frontend surfaces: Mobile and Web. The teams span across multiple products and areas to engage and provide value to our customers, starting with the Home hub in the app or website, which expands into the various product offers and journeys a user can embark on with Affirm. This role will be at the forefront of our front-end facing cross-team projects, working closely with other teams and engineers across our mobile and web technologies, while also evolving and collaborating with every product experience team at Affirm. What You'll Do With the support of your team’s tech lead and manager, you will break down larger projects into individual tasks, deliver them in multiple phases, and collaborate with others to ensure timely delivery of your work. You will support your peers and stakeholders in the product development lifecycle by collaborating with product management, design & analytics by participating in ideation, articulating technical constraints, and partnering on decisions that properly consider risks and trade-offs. You will support the operations and availability of your team’s artifacts by creating and monitoring metrics, escalating when needed, and supporting “keep the lights on” & on-call efforts. You will contribute to a sense of community on your team by engaging in growth and development activities such as participation in the interview process. What We Look For You have a total of 4+ years of experience as a software engineer. You have experience shipping web apps using declarative UI frameworks like React or Vue You have experience shipping mobile apps using native or cross-platform languages like React Native You have experience design

At Affirm, we exist for the moments that matter—giving people a clear, predictable way to pay over time, with no hidden fees, no surprises, and no tradeoffs on what matters most. The Marketplace and App Experience domain is the main pillar of our core consumer strategy, driving the user journey across all of our frontend surfaces: Mobile and Web. The teams span across multiple products and areas to engage and provide value to our customers, starting with the Home hub in the app or website, which expands into the various product offers and journeys a user can embark on with Affirm. This role will be at the forefront of our front-end facing cross-team projects, working closely with other teams and engineers across our mobile and web technologies, while also evolving and collaborating with every product experience team at Affirm. What You'll Do With the support of your team’s tech lead and manager, you will break down larger projects into individual tasks, deliver them in multiple phases, and collaborate with others to ensure timely delivery of your work. You will support your peers and stakeholders in the product development lifecycle by collaborating with product management, design & analytics by participating in ideation, articulating technical constraints, and partnering on decisions that properly consider risks and trade-offs. You will support the operations and availability of your team’s artifacts by creating and monitoring metrics, escalating when needed, and supporting “keep the lights on” & on-call efforts. You will contribute to a sense of community on your team by engaging in growth and development activities such as participation in the interview process. What We Look For You have a total of 4+ years of experience as a software engineer. You have experience shipping web apps using declarative UI frameworks like React or Vue You have experience shipping mobile apps using native or cross-platform languages like React Native You have experience design

POSITION SUMMARY The Leader of Strategic Programs /COS drives internal organizational program and project management on behalf of the Executive Leadership Team (ELT), turning strategic priorities into coordinated, well-governed execution. This role act s as a force multiplier, enabling leaders to focus on high-priority decisions while ensuring that organizational initiatives are executed efficiently ; monitors progress across cross-functional initiatives, keeps stakeholders accountable to deadlines, and removes roadblocks so leadership's strategic agenda moves forward on schedule. The ideal candidate is a creative problem solver with a strong bias toward operational effectiveness, is comfortable using project and work-management tools to bring visibility and structure to fast-moving initiatives and is seeking to build the breadth of experience needed to advance into a leadership role. SPECIFIC JOB RESPONSIBILITIES Strategic Initiative & Program Management Serve as the internal program/project management lead for organization-wide initiatives sponsored by the Executive Leadership Team. Work collaboratively with Executive Leadership to translate strategic priorities into structured plans, workstreams, and measurable milestones. Build and maintain a portfolio view of active initiatives, surfacing status, risks, and dependencies to leadership on a regular cadence . Maintain a keen focus on meeting deadlines under pressure, adjusting plans proactively when priorities or timelines shift. Acting as a liaison, they translate executive priorities to teams and communicate organizational updates back to leadership . They may lead high-impact projects, prepare executives for key meetings, and respond to urgent organizational challenges . Provide data‑backed insights, challenge assumptions, and support executive decision‑making. Stakeholder Accountability & Execution Monitor progress agains

At Affirm, we exist for the moments that matter—giving people a clear, predictable way to pay over time, with no hidden fees, no surprises, and no tradeoffs on what matters most. Our Marketplace is continually evolving to deliver a deeply personalized shopping experience that seamlessly links consumers with merchant partners. By leveraging machine learning alongside rich consumer and merchant data, we aim to simplify and streamline the customer journey around everyday and major purchases with tailored brands, products, deals, and offers. In tandem, we are advancing our Ads Platform which is a key technology that empowers merchant partners to strategically deploy their budgets and reach targeted consumers for maximum incremental impact. What You'll Do With the support of your team’s tech lead and manager, you will break down larger projects into individual tasks, deliver them in multiple phases, and collaborate with others to ensure timely delivery of your work. You will support your peers and stakeholders in the product development lifecycle by collaborating with product management, design & analytics by participating in ideation, articulating technical constraints, and partnering on decisions that properly consider risks and trade-offs. You will support the operations and availability of your team’s artifacts by creating and monitoring metrics, escalating when needed, and supporting “keep the lights on” & on-call efforts. You will contribute to a sense of community on your team by engaging in growth and development activities such as participation in the interview process. What We Look For You have a total of 1.5+ years of experience as a software engineer. You have experience shipping web apps using declarative UI frameworks like React. You have experience designing, developing and launching APIs at scale using languages like Python or Kotlin. You have mastered taking a simple problem or business scenario into a solution that interacts with multiple softwa

At Affirm, we exist for the moments that matter—giving people a clear, predictable way to pay over time, with no hidden fees, no surprises, and no tradeoffs on what matters most. Our Marketplace is continually evolving to deliver a deeply personalized shopping experience that seamlessly links consumers with merchant partners. By leveraging machine learning alongside rich consumer and merchant data, we aim to simplify and streamline the customer journey around everyday and major purchases with tailored brands, products, deals, and offers. In tandem, we are advancing our Ads Platform which is a key technology that empowers merchant partners to strategically deploy their budgets and reach targeted consumers for maximum incremental impact. What You'll Do With the support of your team’s tech lead and manager, you will break down larger projects into individual tasks, deliver them in multiple phases, and collaborate with others to ensure timely delivery of your work. You will support your peers and stakeholders in the product development lifecycle by collaborating with product management, design & analytics by participating in ideation, articulating technical constraints, and partnering on decisions that properly consider risks and trade-offs. You will support the operations and availability of your team’s artifacts by creating and monitoring metrics, escalating when needed, and supporting “keep the lights on” & on-call efforts. You will contribute to a sense of community on your team by engaging in growth and development activities such as participation in the interview process. What We Look For You have a total of 1.5+ years of experience as a software engineer. You have experience shipping web apps using declarative UI frameworks like React. You have experience designing, developing and launching APIs at scale using languages like Python or Kotlin. You have mastered taking a simple problem or business scenario into a solution that interacts with multiple softwa

Who we are About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies—from the world’s largest enterprises to the most ambitious startups—use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone’s reach while doing the most important work of your career. About the team Stripe Checkout helps any business–from fast-growing startups to enterprises–accept payments without building their checkout from scratch. We have a suite of checkout surfaces that range from no- and low-code checkout pages to embedded payment forms and highly customized checkout flows. We’re expanding the suite to support emerging business models and continually optimizing so we can ensure Stripe has the most profitable, safest checkouts on the internet. What you’ll do As a Staff Designer on Checkout, you'll lead the visual and interaction design direction for our most opinionated and optimized checkout surfaces. You’ll define how checkouts should flex to support emerging business models and underserved verticals, taking complex merchant needs and translating them to simple, conversion-optimized solutions. You’ll also contribute to and evolve the backing design system for our checkout surfaces. Responsibilities Define the design direction for new features and checkout surfaces across the conversion funnel Lead design explorations from initial concept through launch Evolve and push boundaries on visual language, component patterns, and design systems Shape early product strategy through design exploration and rapid prototyping, making abstract opportunities tangible for product and engineering partners Represent Checkout in senior reviews and establish the creative bar for new product directions Who you are We’re looking for someone who meet