About Iovance Biotherapeutics, Inc. Iovance Biotherapeutics , Inc. is the global leader in innovating, developing, and delivering tumor infiltrating lymphocyte (TIL) cell therapies for patients with solid tumors. Amtagvi® (lifileucel) is the first FDA-approved, one-time treatment for previously treated advanced melanoma, now approved in three global markets and available at more than 95 authorized treatment centers. The Iovance TIL platform spans registrational trials and next-generation programs in additional solid tumors, including gene-edited and IL-12 tethered TIL therapies, next-generation IL-2, and precision immuno-oncology approaches. As the first and only company to take TIL therapy from concept to a broadly accessible commercial treatment, Iovance operates as an end-to-end cell therapy company, anchored by fully owned, centralized U.S.-based manufacturing that is scaled to serve thousands of cancer patients worldwide each year. For more information, please visit www.iovance.com . Amtagvi® and its accompanying design marks, Proleukin ® , Iovance ® , and IovanceCares™ are trademarks and registered trademarks of Iovance Biotherapeutics, Inc. or its subsidiaries. All other trademarks and registered trademarks are the property of their respective owners. Information on Iovance’s broad, industry-leading patent portfolio is available on the Intellectual Property page on www.iovance.com . Overview Iovance Biotherapeutics is an immuno-oncology company focused on the development and commercialization of novel cancer immunotherapies based on tumor infiltrating lymphocytes (TIL). The Aseptic Manufacturing Technician , role is crucial for the autologous cell therapy manufacturing program. This position requires a broad understanding of theories, techniques, and principles to support manufacturing processes. As an Aseptic Manufacturing Technician I, you will primarily be responsible for th
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About Iovance Biotherapeutics, Inc. Iovance Biotherapeutics , Inc. is the global leader in innovating, developing, and delivering tumor infiltrating lymphocyte (TIL) cell therapies for patients with solid tumors. Amtagvi® (lifileucel) is the first FDA-approved, one-time treatment for previously treated advanced melanoma, now approved in three global markets and available at more than 95 authorized treatment centers. The Iovance TIL platform spans registrational trials and next-generation programs in additional solid tumors, including gene-edited and IL-12 tethered TIL therapies, next-generation IL-2, and precision immuno-oncology approaches. As the first and only company to take TIL therapy from concept to a broadly accessible commercial treatment, Iovance operates as an end-to-end cell therapy company, anchored by fully owned, centralized U.S.-based manufacturing that is scaled to serve thousands of cancer patients worldwide each year. For more information, please visit www.iovance.com . Amtagvi® and its accompanying design marks, Proleukin ® , Iovance ® , and IovanceCares™ are trademarks and registered trademarks of Iovance Biotherapeutics, Inc. or its subsidiaries. All other trademarks and registered trademarks are the property of their respective owners. Information on Iovance’s broad, industry-leading patent portfolio is available on the Intellectual Property page on www.iovance.com . Overview The Senior Project Manager will play a key role in the development, management, and execution of Iovance’s manufacturing sites’ project portfolios in Philadelphia, PA, reporting to the Senior Director, Operational Excellence. This experienced individual will shape project management processes and standards and provide guidance to less experienced project managers. The role will be responsible for planning, leading, and managing the successful execution of complex cross-function
About Iovance Biotherapeutics, Inc. Iovance Biotherapeutics , Inc. is the global leader in innovating, developing, and delivering tumor infiltrating lymphocyte (TIL) cell therapies for patients with solid tumors. Amtagvi® (lifileucel) is the first FDA-approved, one-time treatment for previously treated advanced melanoma, now approved in three global markets and available at more than 95 authorized treatment centers. The Iovance TIL platform spans registrational trials and next-generation programs in additional solid tumors, including gene-edited and IL-12 tethered TIL therapies, next-generation IL-2, and precision immuno-oncology approaches. As the first and only company to take TIL therapy from concept to a broadly accessible commercial treatment, Iovance operates as an end-to-end cell therapy company, anchored by fully owned, centralized U.S.-based manufacturing that is scaled to serve thousands of cancer patients worldwide each year. For more information, please visit www.iovance.com . Amtagvi® and its accompanying design marks, Proleukin ® , Iovance ® , and IovanceCares™ are trademarks and registered trademarks of Iovance Biotherapeutics, Inc. or its subsidiaries. All other trademarks and registered trademarks are the property of their respective owners. Information on Iovance’s broad, industry-leading patent portfolio is available on the Intellectual Property page on www.iovance.com . Overview This position is integral to the continued and planned future growth of Iovance Biotherapeutics’ Cell Therapy Manufacturing Center and capabilities. The Senior Manager, Cost Accounting is responsible for overseeing cost accounting (including cost of goods sold, bill of materials and inventory costing. The Senior Manager provides reporting and analysis to the corporate finance and accounting team, including the SVP, Finance and CFO, to support the strategic and operational planning. T
About Iovance Biotherapeutics, Inc. Iovance Biotherapeutics , Inc. is the global leader in innovating, developing, and delivering tumor infiltrating lymphocyte (TIL) cell therapies for patients with solid tumors. Amtagvi® (lifileucel) is the first FDA-approved, one-time treatment for previously treated advanced melanoma, now approved in three global markets and available at more than 95 authorized treatment centers. The Iovance TIL platform spans registrational trials and next-generation programs in additional solid tumors, including gene-edited and IL-12 tethered TIL therapies, next-generation IL-2, and precision immuno-oncology approaches. As the first and only company to take TIL therapy from concept to a broadly accessible commercial treatment, Iovance operates as an end-to-end cell therapy company, anchored by fully owned, centralized U.S.-based manufacturing that is scaled to serve thousands of cancer patients worldwide each year. For more information, please visit www.iovance.com . Amtagvi® and its accompanying design marks, Proleukin ® , Iovance ® , and IovanceCares™ are trademarks and registered trademarks of Iovance Biotherapeutics, Inc. or its subsidiaries. All other trademarks and registered trademarks are the property of their respective owners. Information on Iovance’s broad, industry-leading patent portfolio is available on the Intellectual Property page on www.iovance.com . Overview The Supervisor, Engineering & Maintenance is responsible for oversight of engineering, maintenance and calibration activities during second shift at Iovance iCTC. This position will be responsible for resolving escalations, technical issues and making sound critical decisions. Typical day to day activities include supporting the repair and maintenance of equipment, utilities and systems serving cGMP Manufacturing, Laboratories and Warehouse facilities. Ensure planned and corrective maintenanc
About Iovance Biotherapeutics, Inc. Iovance Biotherapeutics , Inc. is the global leader in innovating, developing, and delivering tumor infiltrating lymphocyte (TIL) cell therapies for patients with solid tumors. Amtagvi® (lifileucel) is the first FDA-approved, one-time treatment for previously treated advanced melanoma, now approved in three global markets and available at more than 95 authorized treatment centers. The Iovance TIL platform spans registrational trials and next-generation programs in additional solid tumors, including gene-edited and IL-12 tethered TIL therapies, next-generation IL-2, and precision immuno-oncology approaches. As the first and only company to take TIL therapy from concept to a broadly accessible commercial treatment, Iovance operates as an end-to-end cell therapy company, anchored by fully owned, centralized U.S.-based manufacturing that is scaled to serve thousands of cancer patients worldwide each year. For more information, please visit www.iovance.com . Amtagvi® and its accompanying design marks, Proleukin ® , Iovance ® , and IovanceCares™ are trademarks and registered trademarks of Iovance Biotherapeutics, Inc. or its subsidiaries. All other trademarks and registered trademarks are the property of their respective owners. Information on Iovance’s broad, industry-leading patent portfolio is available on the Intellectual Property page on www.iovance.com . Overview Iovance Biotherapeutics is an immuno-oncology company focused on the development and commercialization of novel cancer immunotherapies based on tumor infiltrating lymphocytes (TIL). The Aseptic Manufacturing Technician II , role is crucial for the autologous cell therapy manufacturing program. This position requires a broad understanding of theories, techniques, and principles to support manufacturing processes. As an Aseptic Manufacturing Technician II, you will primarily be responsible fo
Job Title: Locum Speech and Language Therapist – Head and Neck Cancer – Central London Banding: Band 6/7 Location: Central London Start Date: ASAP Rate: £24.00–£32.00 per hour Contract Length: 3 months Working Hours: Full time or part time available Job Overview We are currently seeking an experienced and dedicated Locum Speech and Language Therapist (SALT) to join a specialist Head and Neck Cancer service in Central London. This role offers an excellent opportunity for a Band 6 or Band 7 therapist to provide expert assessment and intervention for patients experiencing communication and swallowing difficulties associated with head and neck cancer. The successful candidate will work as part of a supportive multidisciplinary team, providing high-quality, patient-centred care across the pathway. This role is ideal for a therapist with experience in acute, community, or specialist oncology settings who is looking for a rewarding locum opportunity starting ASAP. Key Responsibilities In this role, you will: • Assess, diagnose, and manage patients with speech, language, voice, and swallowing difficulties related to head and neck cancer. • Provide specialist assessment and intervention plans tailored to individual patient needs. • Work collaboratively with medical teams and wider multidisciplinary professionals to support patient outcomes. • Provide advice and education to patients, families, and healthcare professionals. • Maintain accurate and timely clinical documentation in line with professional standards. • Participate in multidisciplinary meetings and contribute to service development where appropriate. Qualifications and Experience To be considered for this role, you must have: • A recognised degree in Speech and Language Therapy (or equivalent). • HCPC registration and eligibility for membership of the Royal College of Speech and Language Therapists (RCSLT). • Previous experience working within a Head and Neck Cancer, oncology, acute, or specialist SLT setting. • E
Locum Consultant Medical Oncologist – HPB & Breast We are currently seeking an experienced Locum Consultant Medical Oncologist to join a leading NHS Trust for an initial 3-month assignment , with an immediate start available . This is an excellent opportunity for a highly skilled consultant with substantial experience managing both HPB and Breast malignancies within an NHS setting. Essential Requirements Full GMC registration with a licence to practise. Extensive NHS experience at Consultant level in Medical Oncology. Proven expertise in managing HPB and Breast cancer pathways . Ability to independently lead outpatient clinics, systemic anti-cancer therapy (SACT) services, MDT participation, and inpatient oncology care. Strong multidisciplinary working experience within established cancer services. Key Responsibilities Deliver high-quality consultant-led Medical Oncology services. Manage patients with HPB and Breast cancers across outpatient and inpatient settings. Participate in and contribute to relevant MDT meetings. Develop and oversee treatment plans, including systemic therapies. Provide clinical leadership and support to the wider oncology team. Contract Details Start Date: ASAP Duration: Initial 3 months (extension potential available) Hours: Full-time preferred Rate: Negotiable based on experience and availability Why Apply? Immediate start opportunity. Competitive and negotiable rates. Supportive NHS oncology department. Potential for contract extension. Dedicated recruitment and compliance support throughout the placement. Contact Cillean Guihen for further details regarding role For further information or to express interest, please submit your CV along with your availability and GMC details for immediate consideration.
POSITION SUMMARY: Natera is hiring a Machine Learning Scientist to join our AI and computational biology team. This role develops and deploys deep learning models across digital pathology, genomics, transcriptomics, and cell-free DNA (cfDNA) modalities. You will build multimodal AI systems that integrate imaging, molecular, and clinical data, leveraging proprietary genomic and clinical datasets. You will collaborate with scientists, pathologists, bioinformaticians, and software engineers to scale machine learning approaches that advance personalized oncology diagnostics and tumor-informed minimal residual disease (MRD) testing. PRIMARY RESPONSIBILITIES: Design, implement, and evaluate deep learning models across biomedical data modalities, including histopathology imaging, genomic sequencing, transcriptomics, and cfDNA features Develop multimodal AI architectures that integrate H&E whole-slide imaging data with molecular and clinical data sources Build scalable, production-quality machine learning workflows and pipelines using cloud infrastructure (AWS) Apply modern machine learning techniques including convolutional neural networks (CNNs), vision transformers (ViTs), sequence transformers, representation learning, and foundation model fine-tuning Collaborate across technical and clinical teams to translate machine learning prototypes into validated tools Analyze model outputs to generate reproducible biological and clinical insights Document pipelines thoroughly and communicate data-driven findings clearly to cross-functional stakeholders QUALIFICATIONS: PhD in Computer Science, Computational Biology, Biomedical Engineering, Bioinformatics, Statistics, or a related quantitative discipline with a focus on machine learning or AI Core experience developing machine learning models for biomedical applications, specifically in medical imaging, computational pathology, genomics, transcriptomics, multi-omics, or molecular diagnostics Hands-on expertise with PyTorch and
Lynx Analytics is an AI-native consulting firm focused on solving complex challenges for global life sciences organizations. We work with leading pharma, biotech, and medtech organisations to design and deliver high-impact solutions — from AI-driven commercial analytics to pharmacovigilance and patient insights. Our work is hands-on, deeply technical, and built around real client outcomes Our clients include some of the world’s largest pharmaceutical companies — spanning oncology, commercial analytics, and beyond. We are a lean, expert team and we are growing. This is an early, foundational hire — and the opportunity to shape how we go to market. We are hiring a VP of Sales to build and lead our commercial function from the ground up. This is a hands-on leadership role at a real inflection point: Lynx has strong delivery capability, a growing reputation, and a clear set of service offerings — and we are ready to scale. You will work directly with the CEO and leadership team to turn that foundation into a consistent, scalable revenue engine. You will define how we sell, what we lead with, and where we focus. Critically, you will not just build the playbook — you will execute it. Early on, that means personally driving and closing key deals while putting the systems and structure in place to grow the team over time. If you are energised by building something from scratch — and by winning business that genuinely matters — this is that role. What This Involves: Own and deliver on revenue targets across target markets and accounts Personally lead and close strategic engagements, particularly in the early phase Define Lynx’s go-to-market: positioning, service packaging, pricing, and messaging Build the full sales motion — from pipeline generation and qualification through to deal close and account expansion Establish practical, lightweight systems for pipeline visibility, forecasting, and account planning Develop and steward senior relationships across pharma, biotech, an
Primary Responsibilities: Awareness and understanding of relevant GVP modules. Perform medical review of non-serious & serious ICSRs with emphasis on seriousness, expectedness, causality & narrative etc. without missing on quality & compliance. Experience of medical review of ICSRs received from sources such as Spontaneous, Literature, Regulatory Authority, Solicited and Clinical trials. Experience across multiple therapeutic areas such as Oncology, Respiratory, Immunology, Neuroscience, Rare diseases etc. Support triage of cases and determine seriousness and relatedness across products as assigned. Review and verify appropriate selection of adverse events from source documents, assign appropriate MedDRA code, assess labelling and review narrative. Acquire and maintain current knowledge of product portfolio and safety profiles for products across therapeutic areas. Involve in process improvement activities such as implementation of quality control process. Provide medical guidance and expert opinion on the cases to the data entry associates and quality reviewers to help resolve queries. Identify and resolve case issues, coordinate with client therapeutic teams and within functional team and manage as appropriate. Maintain PV expertise and understanding of international safety regulations and guidelines. Responsible for completing the MR activities in the safety database within the stipulated time to comply with service level agreements and regulatory timelines. Provide timely feedback to case processors on the errors/ discrepancies noted. Assist in training/mentoring of other case processing/medical review personnel as necessitated. Adapt to different client case processing conventions and multi-task as per business needs. Perform ad-hoc tasks as advised by the team lead/manager with quality and compliance as per project requirement. Participate in organizational activities to meet objectives suitable for the role/area of expertise. Candidate Profile: Me
POSITION SUMMARY As the Laboratory Director and one of our Laboratory Directors, you have clinical oversight of Natera’s laboratory testing. You ensure that testing is properly performed, and applicable regulatory standards are met. You are responsible for ensuring that the laboratory implements testing while consistently providing accurate and reliable patient test results. PRIMARY RESPONSIBILITIES: Review, approve, and sign-out reports for a variety of clinical molecular/cytogenetic and/or oncologic results, including NIPT, carrier screening, PGD/PGS, products of conception and oncology testing on platforms including SNP array analysis, NGS, and other methodologies. Oversee the review of genetic and CNV variant data: interpret NGS and microarray results in the context of medical literature, online variant databases and other references along with relevant patient demographic data. Provide clinical and technical support for genetic counselors and other laboratory personnel. Set standards for laboratory testing and acceptable levels of analytic performance and ensure these are maintained. Analyze lab data, contribute to or write publications for high-quality scientific journals. May serve as Clinical Consultant. The Clinical Consultant is responsible for ensuring: Test reports include pertinent information for test interpretation, and Availability for consultation concerning test results and the interpretation of those results as they relate to specific patient conditions May serve as Technical Supervisor. The Technical Supervisor is responsible for ensuring: Appropriate test method selection Adequate method verification to determine the accuracy and precision of the test Enrollment of the laboratory in a CMS-approved proficiency testing (PT) program for the test performed PT samples are tested in accordance with the CLIA requirements PT results are returned within the time frames established by the PT program P
Job Title: Physiotherapist - Trauma and Orthopaedics Banding: Band 6 Location: London, Greater London Working Hours: Full-time Start Date: ASAP Rate: £25-30 per hour Duration: Until 5 August We are seeking an exceptionally skilled and motivated Physiotherapist specialising in Trauma and Orthopaedics to join our esteemed client in London. This role requires working in a fast-paced and dynamic environment, where you will be responsible for assessing and treating patients with lower limb fractures, as well as gynae oncology patients. Your advanced expertise will be pivotal in ensuring the precision and reliability of physiotherapy outcomes, which are critical for accurate patient diagnosis and treatment. Key Responsibilities In this role, you will be responsible for providing a specialist level of clinical skill in trauma and orthopaedics physiotherapy, managing a clinical caseload of patients with lower limb fractures and gynae oncology patients. You will use clinical assessments, interview, and observational skills to determine the physiotherapy needs of patients, effectively setting goals and planning interventions. Additionally, you will be involved in complex discharge planning, as patients often require experience with discharge planning. You will work autonomously, maintaining meticulous records and documentation, and collaborating effectively with multidisciplinary healthcare teams to deliver superior patient care. Qualifications and Experience: Extensive experience in trauma and orthopaedics physiotherapy. Experience in assessing and treating patients with lower limb fractures and gynae oncology patients. Strong experience in complex discharge planning. HCPC registration. Bachelor’s degree in Physiotherapy or a related field. Why Work with Pulse? From the moment you register with us, our focus is entirely on you. During our first conversation, you’ll quickly see that we understand your specialty inside and out. Our expert re
Band 7 Locum Senior Dosimetrist Job Title: Senior Dosimetrist Banding: 7 Location: London Working Hours: Monday to Friday 0900-1700 Rate: £32.00 - £33.00 We are currently seeking an experienced Band 7 Locum Senior Dosimetrist to join a leading oncology department in London. This role offers an excellent opportunity to work in a state-of-the-art radiotherapy centre, contributing to high-quality cancer treatment planning. The ideal candidate will have a strong background in radiotherapy dosimetry and treatment planning, working collaboratively with clinical oncologists, radiographers, and physicists. Responsibilities : As a Senior Dosimetrist, you will be responsible for the accurate planning and calculation of radiation treatment dose s for cancer patients, ensuring optimal treatment delivery while minimising exposure to surrounding healthy tissues. You will work with advanced radiotherapy techniques such as IMRT, VMAT, and IGRT, using the latest treatment planning systems. You will liaise closely with oncologists, radiographers, and medical physicists to develop personalised treatment plans, adhering to strict safety protocols and quality assurance standards. Additionally, you will contribute to workflow optimisation, protocol development, and continuous improvement initiatives within the radiotherapy department. Requirements: BSc in Radiotherapy, Medical Physics, or a relevant field. Significant experience in radiotherapy treatment planning and dosimetry. Proficiency with treatment planning systems such as Eclipse, Monaco, or RayStation. Strong understanding of IMRT, VMAT, IGRT, and other advanced radiotherapy techniques. HCPC registration (or equivalent). Ability to work effectively in a multidisciplinary team. Excellent problem-solving skills and attention to detail. Familiarity with quality assurance procedures and radiation safety guidelines. Why work with Pulse? From the moment you register with us, our focus is entirely on you.
At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description At Gilead, our pursuit of a healthier world for all people has led to transformative advances in HIV treatment and prevention, a cure for hepatitis C, and important progress across viral, inflammatory, and oncology diseases. We set bold ambitions in our work to address some of the world’s most urgent public health challenges and improve the lives of patients around the globe. Position Overview The Gilead Patient Solutions (GPS) team operates in almost 140 low-and lower-middle income countries across the world to champion innovative solutions that improve patient outcomes, promote health system sustainability, strengthen infrastructure and uplift comm
Are you interested in working directly for a single sponsor while having the security and additional career opportunities that working for a global CRO can bring? Our team says it’s the best of both worlds…. ClinChoice is searching for a Senior Statistical Programmer Consultant to join one of our clients. ClinChoice is a global full-service CRO with a strong focus on quality, professional development, and supportive culture. As a client-facing role, we are looking for confident candidates with the ability to work independently whilst establishing a high-trust environment with the client’s counterparts. We are seeking an experienced Senior Statistical Programmer with hands-on experience in Gene Therapy clinical trials to lead study-level statistical programming activities. The ideal candidate will have strong SAS programming expertise, a solid understanding of clinical trial data and regulatory requirements, and the ability to independently manage programming deliverables in collaboration with Biostatisticians and cross-functional teams. Experience in Gene Therapy clinical development is essential. Experience in Oncology or Internal Medicine is also valuable. Key Responsibilities Lead statistical programming activities for Gene Therapy clinical trials from study start-up through database lock, analysis, and reporting. Develop, review, and validate SAS programs for SDTM, ADaM, Tables, Listings, and Figures (TLFs). Collaborate with Biostatisticians to interpret study protocols, Statistical Analysis Plans (SAPs), and programming specifications. Develop and validate clinical datasets and statistical outputs for safety and efficacy analyses. Support interim and final analyses, database lock activities, and Clinical Study Report preparation. Ensure programming deliverables comply with CDISC standards and applicable regulatory requirements. Perform independent validation and quality control of datasets, TLFs, and other programming outputs. S
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