Senior Clinical Data Manager Jobs

What you’ll do Own the tissue-class segmentation and labeling models for the ultrasound CT clinical analysis layer, and the pipelines that make them trainable and verifiable. Retune across 2D per-slice, 3D volumetric, and 2D×3D fusion as reconstructed image inputs are continuously updated, and clinical indications for use expand. Define training/evaluation pipelines, datasets, and metrics from the ground up or from open source; map model behavior to user needs and design requirements. Work with data labeling contractors, expert clinicians, and our internal cloud/data teams on labeling specs, QC, and dataset versioning. Help productionize models into a versioned, HIPAA-bound analysis service: reproducible/low-latency inference, per-prediction confidence, drift monitoring, and safe fallbacks. What we’re looking for Strong applied ML experience with a track record of developing new models — architecting, training, and evaluating from scratch as well as benchmarking against existing models. Experience with image segmentation (semantic/instance, 2D and ideally 3D/volumetric) and the modeling and training-data choices that make it robust across diverse patient anatomy. Comfortable moving fluidly between open-ended research iteration and producing quantifiable, testable models. Fluent in modern deep-learning tooling (e.g., PyTorch) and current development practices. Comfortable working under design controls, where model changes carry documentation and verification weight. Useful experience Image segmentation and label generation with modern architectures (U-Net / nnU-Net, 3D U-Net, transformer-based and promptable segmentation like SAM), including the geometry that ties voxel- and mesh-level predictions back to a coordinate frame. Learning under limited or noisy supervision: self-supervised / semi-supervised methods (masked autoencoders, contrastive pretraining like DINO/SimCLR), active learning, weak labels, and simulation-driven pretraining. Hands-on experience with data

ROLE SUMMARY Clinical development & Operation is a critical domain where scientific innovation is translated into evidence that supports new medicines and improves outcomes for patients and trial participants globally. It operates at the intersection of clinical operations, data science, digital platforms, external partners, and global regulatory expectations, requiring solutions that are scalable, compliant, user-centered, and trusted across diverse stakeholders. Digital platforms, data products, and AI-enabled capabilities are increasingly essential to improving clinical trial planning, execution, monitoring, and decision-making. This role helps deliver responsible technology solutions that strengthen data quality, reduce operational complexity, support audit readiness, and enhance the experience of clinical teams, investigators, and participants while keeping participant safety at the center of the domain As a Sr. Associate, AI and Analytics Data Engineer, you will be part of a global team responsible for engineering the trusted, scalable, and governed data foundation for a major AI-driven platform serving the Clinical Development and Operations domain. You will design and build reusable data products, pipelines, and processing frameworks that integrate complex clinical, operational, and external data; enable advanced analytics, machine learning, and generative AI use cases; and meet enterprise expectations for security, privacy, quality, lineage, reliability, and regulatory compliance. Join our diverse team in making an impact on patient health through the application of cutting-edge technology and collaboration. ROLE RESPONSIBILITIES Design, build, test, and operate scalable batch and streaming data pipelines that ingest, standardize, and integrate clinical, operational, scientific, and external

About Formation Bio Formation Bio is a tech and AI driven pharma company differentiated by radically more efficient drug development. Advancements in AI and drug discovery are creating more candidate drugs than the industry can progress because of the high cost and time of clinical trials. Recognizing that this development bottleneck may ultimately limit the number of new medicines that can reach patients, Formation Bio, founded in 2016 as TrialSpark Inc., has built technology platforms, processes, and capabilities to accelerate all aspects of drug development and clinical trials. Formation Bio partners, acquires, or in-licenses drugs from pharma companies, research organizations, and biotechs to develop programs past clinical proof of concept and beyond, ultimately helping to bring new medicines to patients. The company is backed by investors across pharma and tech, including a16z, Sequoia, Sanofi, Thrive Capital, John Doerr, Spark Capital, SV Angel Growth, and others. You can read more at the following links: Our Vision for AI in Pharma Our Current Drug Portfolio Our Technology & Platform At Formation Bio, our values are the driving force behind our mission to revolutionize the pharma industry. Every team and individual at the company shares these same values, and every team and individual plays a key part in our mission to bring new treatments to patients faster and more efficiently. About the Position This role sits on Formation's Asset Acquisition & Diligence (AAD) team. In the course of evaluating and completing diligence on individual drug assets, our Data Science team runs sophisticated one-off analyses (e.g. a novel algorithm run against a specific gene or indication, a causal model built for a specific therapeutic hypothesis). Much of that work directly shapes a specific deal decision in the moment. This role exists to take these and scale them into strategies and tools that can provide an organization level advantage. You

About Formation Bio Formation Bio is a tech and AI driven pharma company differentiated by radically more efficient drug development. Advancements in AI and drug discovery are creating more candidate drugs than the industry can progress because of the high cost and time of clinical trials. Recognizing that this development bottleneck may ultimately limit the number of new medicines that can reach patients, Formation Bio, founded in 2016 as TrialSpark Inc., has built technology platforms, processes, and capabilities to accelerate all aspects of drug development and clinical trials. Formation Bio partners, acquires, or in-licenses drugs from pharma companies, research organizations, and biotechs to develop programs past clinical proof of concept and beyond, ultimately helping to bring new medicines to patients. The company is backed by investors across pharma and tech, including a16z, Sequoia, Sanofi, Thrive Capital, John Doerr, Spark Capital, SV Angel Growth, and others. You can read more at the following links: Our Vision for AI in Pharma Our Current Drug Portfolio Our Technology & Platform At Formation Bio, our values are the driving force behind our mission to revolutionize the pharma industry. Every team and individual at the company shares these same values, and every team and individual plays a key part in our mission to bring new treatments to patients faster and more efficiently. About the Position The Data Governance Associate Director/Director is a critical member of the Quality Governance team, with a primary focus on data governance and AI oversight across Formation Bio's R&D organization. This role serves as Process Owner for R&D Data and Records Integrity and as Business Owner for key quality technology systems (Veeva Quality Docs, DocuSign Part 11), and owns the organization's inventory of R&D data and AI applications, along with their associated risk assessments. Reporting directly to the Head of Quality with no inte

Job Description: Help guide report strategy, help determine important safety concerns and review medical and medical safety content that will be included or discussed in the report, including but not limited to safety signals, health authority requests, safety-related literature, adverse event case reviews, benefit-risk assessments, and overall medical assessments and conclusions. Work in collaboration with contributing team members, particularly with the reports assigned to the Global Risk Assessment and Safety Physician. Review all stages of the report that are assigned during the report authoring process, record their recommended revisions, and indicate completion of their reviews in the corresponding systems. Key Responsibilities: Provide medical and scientific judgment in the evaluation of data pertaining to the efficacy and safety of Client products including, but not limited to, PBRER-PSURs and benefit-risk evaluations Review and contribute to strategy discussions, including determination of the important safety concerns and review of draft/final data, HA feedback topics, signals, and benefit-risk evaluation. Coordinate with Global Risk Assessment and Safety Physicians regarding PBRER steps and hand-offs and collaborate with other members of the report authoring team. Review the drafts and final reports as assigned and provide feedback, which may include pre-initial, drafts, drafts, final drafts, and final reports as assigned. Qualifications: Requirement: Licensed Medical Physician Experience in Drug Safety and Pharmacovigilance (PV) Concepts, regulatory requirements, research principles, and safety data analysis. 1-3 years of experience in pharmaceutical regulations and R&D processes. Technical Skills: the ability to analyze, interpret, and present complex data in a concise and understandable scientific manner, both orally and in written format, is essential. Attention to detail: diligence in record-keeping and records organizatio

Responsibilities: Annotate Case Report Form (acrf.pdf) following FDA/CDISC or sponsor guidelines. Develop SDTM specifications and generate SDTM datasets using SAS; Develop ADaM,specifications and generate ADaM datasets using SAS based on Statistical Analysis Plan; Develop Tables, Listings, Graphs, Patient Profile in support of the Clinical Study Report, Posters, Manuscripts; Develop ADaM data, Tables, Listings, Figures for Integrated Summary of Safety (ISS) and Integrated Summary of Efficacy (ISE) Create electronic submission packages to FDA, e.g., define.xml or define.pdf following FDA guidelines with no supervision. Expert-level in analyze information and develop innovative solutions to programming and data analysis challenges; Serve as point of contact (POC) of programming with statisticians for statistical input and analysis interpretation; Follow and reinforce regulatory agency requirements during daily job. Serve as a programming team lead and contribute to department initiatives. Provide guidance, mentoring, training for team members and help solve issues from cross-functional teams; Review draft and final production deliverables for project to ensure quality and consistency. Work with global team or sponsors to coordinate project deliverables, timelines and resources. Skills and Responsibilities: Bachelor’s/Master’s degree in Statistics, Mathematics, Computer Science, Electrical Engineering, Biotechnology or related scientific disciplines with 5+years of clinical programming experience. Proven knowledge and training in high level computing languages such as. SAS, C/C++, Java, R, Python, MATLAB and SQL. Database programming experience is a plus. Expert-level in decoding programming logic and assembling programming code based on logic provided and be able to explain to team members. Expert level in applying concept in Artificial Intelligence and Machine Learning in real world. In-depth knowledge of ICH, Good Clinical Practices, Clinical research, Clinical tria

About the Role We are building a new class of clinical-grade AI agents powered by a foundational model that unifies 3D volumetric medical data and textual reasoning . These agents will assist with radiology workflows, treatment planning, case summarization, longitudinal patient analysis, and human-in-the-loop clinical decision support. In this role, you will design the agent layer that transforms a powerful multimodal foundation model into a safe, reliable, adaptive medical assistant capable of analyzing 3D scans, retrieving past cases, explaining findings, and coordinating multi-step reasoning chains. This position is ideal for researchers from multimodal/VLM/CLIP ecosystems who want to move up the stack into autonomous medical reasoning , multimodal alignment, and real-world clinical impact. What You Will Work On Architect LLM-driven medical agents capable of: Reading & interpreting 3D medical volumes (MRI, CT, PET). Answering radiology questions, generating report drafts, and performing differential reasoning. Retrieving similar prior cases using contrastive embeddings. Synthesizing multi-instance evidence across scans, labs, and notes. Executing multi-step “clinical workflows”—image → analysis → summary → recommendation. Integrate clinical agents with the 3D foundation model’s representations, enabling structured medical reasoningand contextual memory across longitudinal data. Develop evaluation frameworks for trustworthiness, interpretability, calibration, and clinical safety. Collaborate with clinicians and scientists to co-design tasks, datasets, and validation protocols. Benchmark models against open and proprietary datasets: MIMIC, CheXpert, MosMed, LiTS, BraTS, and India-specific clinical corpora. Publish findings at top-tier venues (MICCAI, NeurIPS, AAAI, EMNLP). Work with regulatory and product teams to translate research into medically viable systems. Why This Role Appeals to CLIP / VLM / Chitrarth / Patram Authors A rare opportunity to work at the

Beacon Biosignals is transforming precision medicine for the brain, from clinical development to clinical care. For Life Sciences partners, we offer the leading at-home EEG platform for clinical development of novel therapeutics for neurological, psychiatric, and sleep disorders. Our Diagnostics business is building the most comprehensive at-home platform for precision diagnostics, combining EEG and cardiopulmonary signals to deliver reimbursable assessments for sleep and central nervous system disorders. Together, we're changing the way patients are diagnosed and treated for any disorder that affects brain physiology. As a Senior Mobile Engineer focused on device connectivity, you'll help power Beacon's mission by building the native iOS and Android BLE layer that connects our EEG headbands and other wearables to the apps patients and clinicians rely on. Your work will determine how reliably we capture high-fidelity data in homes, clinics, and trial sites. This isn't just another app. You'll build tools that help unlock insights into neurological, psychiatric, and sleep disorders, with the potential to improve lives at scale. Beacon's robust asynchronous work practices ensure a first-class remote work experience, and we also have in-person office hubs in Boston and New York. For this position we will consider candidates based anywhere in the US Eastern time zone. What success looks like As part of our small, mission-driven Mobile Apps Team, you will: Lead development of our native iOS and Android BLE device SDKs. Own connection reliability, data throughput, and battery performance for device communication across a wide range of phones, OS versions, and real-world environments. Partner closely with our Devices team on firmware interfaces, GATT profiles, and device behavior. Expose device capabilities to our React Native applications through clean, well-tested native modules. Own the observability of device connectivity, using telemetry and field feedback from real u

Beacon Biosignals is transforming precision medicine for the brain, from clinical development to clinical care. For Life Sciences partners, we offer the leading at-home EEG platform for clinical development of novel therapeutics for neurological, psychiatric, and sleep disorders. Our Diagnostics business is building the most comprehensive at-home platform for precision diagnostics, combining EEG and cardiopulmonary signals to deliver reimbursable assessments for sleep and central nervous system disorders. Together, we're changing the way patients are diagnosed and treated for any disorder that affects brain physiology. As a Senior Mobile App Engineer, you'll help power Beacon's mission by building the cross-platform React Native apps that patients and clinicians use with our EEG headbands and other wearables. Your work will shape how people capture high-fidelity data and how easily they move through clinical trials and at-home diagnostics. This isn't just another app. You'll build tools that help unlock insights into neurological, psychiatric, and sleep disorders, with the potential to improve lives at scale. Beacon's robust asynchronous work practices ensure a first-class remote work experience, and we also have in-person office hubs in Boston and New York. For this position we will consider candidates based anywhere in the US Eastern time zone. What success looks like As part of our small, mission-driven Mobile Apps Team, you will: Lead development of our React Native mobile applications across iOS and Android. Design and implement UX workflows for clinical trial participants and at-home diagnostic patients. Own the user experience, performance, reliability, and observability of the apps and features you build, using feedback from real users across diverse use cases and environments. Work with engineers on our native iOS and Android BLE device SDKs to integrate device capabilities cleanly into the app. Partner with our Devices team, other Platform teams, and produ

Become a part of our caring community Most AI engineering jobs are a thin wrapper around a model API. This role is different. We build the platform that transforms millions of clinical documents into trusted, actionable data. Our systems use large language models (LLMs) to read medical records, extract structured facts, answer complex questions with citations back to the source document, and route ambiguous cases to human experts for review. Our users make decisions that impact real healthcare outcomes, so “good enough” is not good enough. Building AI systems that are accurate, reliable, auditable, and scalable is at the core of this role. As a Senior AI Applied Engineer, you will design, build, deploy, and operate production AI systems used at scale within one of the largest health insurers in the United States. You will own solutions end-to-end, from user experience and APIs to model orchestration, evaluation frameworks, infrastructure, and production operations. Why Join Us Build production AI systems where LLMs are in the critical path, not just demos or proofs of concept. Work on extraction, retrieval, agentic workflows, and human-review systems that process real healthcare data at scale. Own projects end-to-end across frontend, backend, AI orchestration, infrastructure, deployment, and operations. Solve challenging problems around accuracy, explainability, traceability, and reliability in regulated environments. Ship quickly in a small, high-impact team that embraces AI-assisted development and rigorous quality standards. Build systems that continuously improve through expert feedback, evaluations, and human-in-the-loop workflows. Key Responsibilities Design, develop, and deploy full-stack AI-powered application

Beacon Biosignals is transforming precision medicine for the brain, from clinical development to clinical care. For Life Sciences partners, we offer the leading at-home EEG platform for clinical development of novel therapeutics for neurological, psychiatric, and sleep disorders. Our Diagnostics business is building the most comprehensive at-home platform for precision diagnostics, combining EEG and cardiopulmonary signals to deliver reimbursable assessments for sleep and central nervous system disorders. Together, we're changing the way patients are diagnosed and treated for any disorder that affects brain physiology. Beacon Biosignals is seeking a Senior Algorithm and Machine Learning engineer! As part of Beacon's analytics and machine learning domain, you'll work alongside fellow data scientists, neuroscientists, engineers, and clinicians to scope, build, deploy, and maintain the machine and deep learning models that analyze brain and biosignal data for advancing sleep, neurological, and psychiatric therapy development. At Beacon, we've found that cultural and scientific impact is driven most by those who lead by example. As such, we're always seeking out new contributors whose work demonstrates innate curiosity, a bias toward simplicity, an eye for composability, a self-service mindset, and—most of all—a deep empathy toward colleagues, stakeholders, users, and patients. We believe a diverse team builds more robust systems and achieves higher impact. Beacon's work practices ensure a first-class remote work experience, but we also have in-person office hubs in Boston, New York City and Paris. This is a fully remote role based anywhere in the U.S. What success looks like Participate in and lead the entire biosignal-based algorithm development lifecycle for medical devices including specifications and requirements gathering, data curation and labeling, development, failure-analysis, production, maintenance, and documentation. Select, implement, and develop the

Beacon Biosignals is transforming precision medicine for the brain, from clinical development to clinical care. For Life Sciences partners, we offer the leading at-home EEG platform for clinical development of novel therapeutics for neurological, psychiatric, and sleep disorders. Our Diagnostics business is building the most comprehensive at-home platform for precision diagnostics, combining EEG and cardiopulmonary signals to deliver reimbursable assessments for sleep and central nervous system disorders. Together, we're changing the way patients are diagnosed and treated for any disorder that affects brain physiology. Beacon Biosignals is seeking a Machine Learning engineer! As part of Beacon's analytics and machine learning domain, you'll work alongside fellow data scientists, neuroscientists, engineers, and clinicians to scope, build, deploy, and maintain the machine and deep learning models that analyze brain and biosignal data for advancing sleep, neurological, and psychiatric therapy development. At Beacon, we've found that cultural and scientific impact is driven most by those who lead by example. As such, we're always seeking out new contributors whose work demonstrates innate curiosity, a bias toward simplicity, an eye for composability, a self-service mindset, and—most of all—a deep empathy toward colleagues, stakeholders, users, and patients. We believe a diverse team builds more robust systems and achieves higher impact. Beacon's robust asynchronous work practices ensure a first-class remote work experience, but we also have in-person office hubs in Boston, New York City and Paris. This is a primarily remote role for individuals based near Paris. What success looks like Participate in and lead the entire biosignal-based algorithm development lifecycle for medical devices including specifications and requirements gathering, data curation and labeling, development, failure-analysis, production, maintenance, and documentation. Select, implement, and d

At Curai, we believe that access to high-quality healthcare is a fundamental human right, not a privilege. Our mission is to radically transform healthcare by harnessing the power of artificial intelligence and clinical expertise to make care more affordable, accessible, and effective for everyone. We are looking for a Senior Software Engineer, Marketing Platform, to build the systems that help people discover Curai Health and find care. You’ll own the web, measurement, and data integration systems to support marketing and growth. What You'll do as a Senior Software Engineer, Marketing Platform In a typical day in the life of a Curai Senior Software Engineer, you’ll: Turning priorities from marketing into scoped engineering projects Define funnel events, implement client and server side tracking, and reconcile conversion data with warehouse reporting. Build SQL models and dashboards to examine cost per visit and cohort behavior Support the build pipeline and ClickHouse data behind our MTA tooling Designing, building, and maintaining web features and the APIs and data flows supporting them Investigating site performance, conversion, and data quality issues, then shipping improvements Reviewing code, improving tests and monitoring, and making technical decisions with the broader engineering team What You'll Need We recognize not everyone will have all of these requirements. If you

Opportunity Overview: We are seeking a Senior AI Engineer to join our Engineering team. In this role, you'll design retrieval architectures, build AI-powered agents, and own production deployments that serve health insurance plans covering over 15 million people. You'll partner closely with product, data science, and clinical teams to build the foundation that transforms how clinical intelligence is delivered at scale - from hands-on code to HIPAA-compliant systems that directly improve healthcare outcomes. This is an opportunity to work at the intersection of cutting-edge AI and real-world impact, in a fast-paced, collaborative environment. This is a remote-first role that may require travel to Boston, MA for new hire onboarding and occasional in-person team meetings and company events. What you’ll do: Agent Development: Participate in the development, evaluation, and deployment of Cohere’s AI-powered agents and applications. Data & Retrieval Architecture: Design data and retrieval architectures that give AI agents the right context, across diverse healthcare sources. Hands-On Engineering: Design, review, and own high-quality agentic code — leading releases, production deployments and on-call support. Cross-Functional Collaboration: Work closely with ML/DS teams, product teams, and architects to understand requirements and ensure systems meet business needs. Security & Compliance: Ensure all agentic components comply with healthcare security and privacy regulations (e.g., HIPAA) and adhere to industry best practices for security. Agile Development: Contribute to sprint planning, execution, and retrospectives, driving efficiency and velocity within the engineering team and collaborating closely with stakeholders to align with product goals and business priorities. What you’ll need: 5+ years of experience in the software development lifecycle, with demonstrated experience working with popular agent frameworks and language models. Expertise in one

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Position Summary We are seeking a skilled and analytical Senior Product Analytics Associate to lead the development and execution of a data-driven product roadmap. The ideal candidate will have a deep understanding of product analytics, strong problem-solving skills, and experience working with cross-functional teams to support strategic initiatives. As a Senior Product Analytics Associate, you will work closely with cross-functional teams including engineering, product, and clinical operations. Roles and Responsibilities: Define, track, and report on product metrics including performance and profitability Build and maintain robust data transformation models using dbt (or similar frameworks like Dataform or SQL-based ETL tools) to ensure analytics-ready datasets Design and interpret A/B tests; when A/B testing is not feasible, apply causal inference methods (e.g., Diff-in-Diff, Propensity Score Matching) to determine product efficacy. Develop ROI projections for analytics projects to prioritize deliverables by business impact Tell compelling stories through data, articulating technical information to a non-technical audience Build and maintain Power BI dashboards to