Senior Lead Structural Analysis Engineer Jobs

Use Your Power for Purpose At Pfizer, our purpose is to deliver breakthroughs that transform patients' lives. Central to this mission is our Research and Development team, which strives to convert advanced science and cutting-edge technologies into impactful therapies and vaccines. Whether you are engaged in discovery sciences, ensuring drug safety and efficacy, or supporting clinical trials, your role is crucial. You will leverage innovative design and process development capabilities to expedite the delivery of top-tier medicines to patients globally. Role Summary Pfizer’s Machine Learning and Computational Sciences (MLCS) group is seeking a Senior Machine Learning Scientist to lead independent and collaborative research in computational antibody design and optimization. This position focuses on developing and applying modern computational and machine-learning approaches to accelerate the discovery of next-generation biologic therapeutics. Positioned at the intersection of machine learning, protein science, and therapeutic discovery, the role is ideal for candidates eager to translate foundational AI research into real-world drug design. It offers the opportunity to join an innovative, collaborative environment that supports professional growth through mentorship, knowledge sharing, and the freedom to pursue impactful science. What You Will Achieve In this role, you will: Conduct original research in computational antibody engineering, with an emphasis on sequence- and structure-based generative modeling. Develop and deploy state-of-the-art machine-learning methods for multi-objective, constraint-aware antibody optimization that balances affinity, stability, and developability. Apply proprietary computational frameworks and machine-learning models to predict antibody developability and affinity. Leverage NGS-derived antibody repertoires to info

Everpure (NYSE: P) has evolved from storage pioneer to data platform, closing fiscal 2026 with $3.7 billion in revenue, its first billion-dollar quarter, and accelerating growth into FY27. Our strategic agenda spans the companies defining the next era of technology - hyperscalers, AI labs, the AI hardware supply chain, data platform providers, and the broader AI ecosystem. This type of work—work that changes the world—is what the tech industry was founded on. So, if you're ready to seize the endless opportunities and leave your mark, come join us. The Role The Strategic Program Manager will lead high-impact growth and transformation programs across Advanced Services, turning strategic priorities into coordinated, measurable execution. Working across Sales, Delivery, Portfolio, Finance and other Everpure organizations, the role will establish and run programs designed to accelerate services growth, customer adoption and organizational transformation. Key Responsibilities Strategic Growth Programs — Design, launch and manage programs that accelerate adoption, pipeline, bookings and revenue growth, including incentive-led and customer adoption initiatives. Program Strategy & Execution — Translate strategic priorities into structured programs with clear objectives, work streams, milestones, ownership and measurable outcomes. Acquisition & Organizational Integration — Lead Services integration activities associated with acquisitions, new technologies or organizational changes, coordinating capabilities, processes, people and GTM readiness. Cross-functional Leadership — Coordinate stakeholders across Advanced Services, Sales, Portfolio, Product, Finance and Operations to drive execution without relying on direct authority. Commercial & Performance Management — Establish business cases, success measures and reporting to understand program adoption, investment effectiveness and commercial impact. GTM & Field Activation — Partner with Services Sales and Enabl

About Vercel: Vercel is the agentic infrastructure company, freeing people and agents to ship what's next. For more than a decade we've helped builders move from idea to production with speed, security, and exceptional developer experience. Now we're scaling our products for both agents and people to ship and run software, built in the open and trusted by OpenAI, PayPal, Ramp, Supreme, and millions of developers worldwide. About the Role: We are seeking a Senior Deal Desk Analyst to join the Deal Desk team within our Revenue Operations function. This is a high-impact, high-visibility role at the center of how we structure, price, and close business globally — partnering with Sales, Finance, Legal, and Product to turn deals into signed revenue. You will lead the quote-to-contract execution cycle for our global sales team while helping build the systems, processes, and playbooks that scale a world-class Deal Desk. As the organization continues through a period of rapid growth, we are looking for someone who wants to shape the function rather than inherit it — bringing structure to ambiguity, modernizing how deals get done, and raising the bar for commercial excellence. This position reports to the Senior Manager, Global Deal Desk, and is preferably based in a hybrid capacity out of our London office, working standard US business hours. What you will do Deal Management — Own the day-to-day deal review and closing process end to end, including deal approvals, deal structuring, and quote configuration within Vercel CPQ, ensuring every deal is executed accurately and on time. Commercialization & Execution — Drive deal execution in close partnership with Finance, Legal, GTM, Partnerships, Product, and Pricing. Design, build, and continuously optimize the sales and deal processes that bring new pricing, packaging, and product launches to market. Trusted Advisor — Serve as the subject-matter expert for the Sales organization, providing deal guidance and operational suppo

Elastic, the Search AI Company, enables everyone to find the answers they need in real time, using all their data, at scale — unleashing the potential of businesses and people. The Elastic Search AI Platform, used by more than 50% of the Fortune 500, brings together the precision of search and the intelligence of AI to enable everyone to accelerate the results that matter. By taking advantage of all structured and unstructured data — securing and protecting private information more effectively — Elastic’s complete, cloud-based solutions for search, security, and observability help organizations deliver on the promise of AI. What is The Role We're looking for a Senior Software Engineer to join our Streams UI team, where you'll have the chance to shape and enhance our user interface, making it more intuitive and engaging for our users. In this role, you'll work on Fleet. Fleet is the central management experience for Elastic Agent in Kibana. You'll also work on Streams. Streams is our new tool for handling log data. This includes ingesting, organizing, parsing, enriching, and setting retention for the data. You will be part of a skilled group of engineers and designers. You will contribute your expertise and learn from others. If you enjoy tackling complex challenges and want to make a meaningful impact on our product, we’d love to hear from you. What You Will Be Doing Design and implement intuitive user interface components that enhance user commitment, using TypeScript, React, and Node.js. Integrate front-end elements seamlessly with back-end services to ensure a smooth user experience. Conduct usability testing and gather user feedback to drive continuous improvements. Own complex, loosely-defined problems end-to-end: shape the approach, split the work if needed, make the key technical decisions, and deliver. Lead discussions on architecture and system design. During these discussions, consider trade-offs. Also, think about backwards compatibility, performance, and

Elastic, the Search AI Company, enables everyone to find the answers they need in real time, using all their data, at scale — unleashing the potential of businesses and people. The Elastic Search AI Platform, used by more than 50% of the Fortune 500, brings together the precision of search and the intelligence of AI to enable everyone to accelerate the results that matter. By taking advantage of all structured and unstructured data — securing and protecting private information more effectively — Elastic’s complete, cloud-based solutions for search, security, and observability help organizations deliver on the promise of AI. What is The Role We're looking for a Senior Software Engineer to join our Streams UI team, where you'll have the chance to shape and enhance our user interface, making it more intuitive and engaging for our users. In this role, you'll work on Fleet. Fleet is the central management experience for Elastic Agent in Kibana. You'll also work on Streams. Streams is our new tool for handling log data. This includes ingesting, organizing, parsing, enriching, and setting retention for the data. You will be part of a skilled group of engineers and designers. You will contribute your expertise and learn from others. If you enjoy tackling complex challenges and want to make a meaningful impact on our product, we’d love to hear from you. What You Will Be Doing Design and implement intuitive user interface components that enhance user commitment, using TypeScript, React, and Node.js. Integrate front-end elements seamlessly with back-end services to ensure a smooth user experience. Conduct usability testing and gather user feedback to drive continuous improvements. Own complex, loosely-defined problems end-to-end: shape the approach, split the work if needed, make the key technical decisions, and deliver. Lead discussions on architecture and system design. During these discussions, consider trade-offs. Also, think about backwards compatibility, performance, and

Elastic, the Search AI Company, enables everyone to find the answers they need in real time, using all their data, at scale — unleashing the potential of businesses and people. The Elastic Search AI Platform, used by more than 50% of the Fortune 500, brings together the precision of search and the intelligence of AI to enable everyone to accelerate the results that matter. By taking advantage of all structured and unstructured data — securing and protecting private information more effectively — Elastic’s complete, cloud-based solutions for search, security, and observability help organizations deliver on the promise of AI. What is The Role We're looking for a Senior Software Engineer to join our Streams UI team, where you'll have the chance to shape and enhance our user interface, making it more intuitive and engaging for our users. In this role, you'll work on Fleet. Fleet is the central management experience for Elastic Agent in Kibana. You'll also work on Streams. Streams is our new tool for handling log data. This includes ingesting, organizing, parsing, enriching, and setting retention for the data. You will be part of a skilled group of engineers and designers. You will contribute your expertise and learn from others. If you enjoy tackling complex challenges and want to make a meaningful impact on our product, we’d love to hear from you. What You Will Be Doing Design and implement intuitive user interface components that enhance user commitment, using TypeScript, React, and Node.js. Integrate front-end elements seamlessly with back-end services to ensure a smooth user experience. Conduct usability testing and gather user feedback to drive continuous improvements. Own complex, loosely-defined problems end-to-end: shape the approach, split the work if needed, make the key technical decisions, and deliver. Lead discussions on architecture and system design. During these discussions, consider trade-offs. Also, think about backwards compatibility, performance, and

Elastic, the Search AI Company, enables everyone to find the answers they need in real time, using all their data, at scale — unleashing the potential of businesses and people. The Elastic Search AI Platform, used by more than 50% of the Fortune 500, brings together the precision of search and the intelligence of AI to enable everyone to accelerate the results that matter. By taking advantage of all structured and unstructured data — securing and protecting private information more effectively — Elastic’s complete, cloud-based solutions for search, security, and observability help organizations deliver on the promise of AI. What is The Role We're looking for a Senior Software Engineer to join our Streams UI team, where you'll have the chance to shape and enhance our user interface, making it more intuitive and engaging for our users. In this role, you'll work on Fleet. Fleet is the central management experience for Elastic Agent in Kibana. You'll also work on Streams. Streams is our new tool for handling log data. This includes ingesting, organizing, parsing, enriching, and setting retention for the data. You will be part of a skilled group of engineers and designers. You will contribute your expertise and learn from others. If you enjoy tackling complex challenges and want to make a meaningful impact on our product, we’d love to hear from you. What You Will Be Doing Design and implement intuitive user interface components that enhance user commitment, using TypeScript, React, and Node.js. Integrate front-end elements seamlessly with back-end services to ensure a smooth user experience. Conduct usability testing and gather user feedback to drive continuous improvements. Own complex, loosely-defined problems end-to-end: shape the approach, split the work if needed, make the key technical decisions, and deliver. Lead discussions on architecture and system design. During these discussions, consider trade-offs. Also, think about backwards compatibility, performance, and

Elastic, the Search AI Company, enables everyone to find the answers they need in real time, using all their data, at scale — unleashing the potential of businesses and people. The Elastic Search AI Platform, used by more than 50% of the Fortune 500, brings together the precision of search and the intelligence of AI to enable everyone to accelerate the results that matter. By taking advantage of all structured and unstructured data — securing and protecting private information more effectively — Elastic’s complete, cloud-based solutions for search, security, and observability help organizations deliver on the promise of AI. What is The Role We're looking for a Senior Software Engineer to join our Streams UI team, where you'll have the chance to shape and enhance our user interface, making it more intuitive and engaging for our users. In this role, you'll work on Fleet. Fleet is the central management experience for Elastic Agent in Kibana. You'll also work on Streams. Streams is our new tool for handling log data. This includes ingesting, organizing, parsing, enriching, and setting retention for the data. You will be part of a skilled group of engineers and designers. You will contribute your expertise and learn from others. If you enjoy tackling complex challenges and want to make a meaningful impact on our product, we’d love to hear from you. What You Will Be Doing Design and implement intuitive user interface components that enhance user commitment, using TypeScript, React, and Node.js. Integrate front-end elements seamlessly with back-end services to ensure a smooth user experience. Conduct usability testing and gather user feedback to drive continuous improvements. Own complex, loosely-defined problems end-to-end: shape the approach, split the work if needed, make the key technical decisions, and deliver. Lead discussions on architecture and system design. During these discussions, consider trade-offs. Also, think about backwards compatibility, performance, and

Elastic, the Search AI Company, enables everyone to find the answers they need in real time, using all their data, at scale — unleashing the potential of businesses and people. The Elastic Search AI Platform, used by more than 50% of the Fortune 500, brings together the precision of search and the intelligence of AI to enable everyone to accelerate the results that matter. By taking advantage of all structured and unstructured data — securing and protecting private information more effectively — Elastic’s complete, cloud-based solutions for search, security, and observability help organizations deliver on the promise of AI. What is The Role We're looking for a Senior Software Engineer to join our Streams UI team, where you'll have the chance to shape and enhance our user interface, making it more intuitive and engaging for our users. In this role, you'll work on Fleet. Fleet is the central management experience for Elastic Agent in Kibana. You'll also work on Streams. Streams is our new tool for handling log data. This includes ingesting, organizing, parsing, enriching, and setting retention for the data. You will be part of a skilled group of engineers and designers. You will contribute your expertise and learn from others. If you enjoy tackling complex challenges and want to make a meaningful impact on our product, we’d love to hear from you. What You Will Be Doing Design and implement intuitive user interface components that enhance user commitment, using TypeScript, React, and Node.js. Integrate front-end elements seamlessly with back-end services to ensure a smooth user experience. Conduct usability testing and gather user feedback to drive continuous improvements. Own complex, loosely-defined problems end-to-end: shape the approach, split the work if needed, make the key technical decisions, and deliver. Lead discussions on architecture and system design. During these discussions, consider trade-offs. Also, think about backwards compatibility, performance, and

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Position Summary The Senior Manager, Reimbursement Strategy & Analytics will lead the transformation of CVS’s approach to evaluating competitive pharmacy reimbursement performance across the marketplace. This role will be accountable for developing a new, scalable methodology for measuring various Payer related programs, enabling a deeper understanding of how CVS competes and where strategic opportunities exist. The Senior Manager will provide analytical leadership, market insight, and strategic recommendations that help guide CVS’s reimbursement strategy and strengthen its position in the marketplace. Required Qualifications 7+ years of experience in analytics, finance, strategy, or consulting Demonstrated critical thinking and structured problem‑solving skills Demonstrated ability to synthesize data from multiple sources to derive conclusions and recommendations Strong understanding of how value is created within complex financial models Ability to identify base‑level economic levers and trade‑offs Experience working independently in ambiguous environments and driving work e

Here at Appian, our values of Intensity and Excellence define who we are. We set high standards and live up to them, ensuring that everything we do is done with care and quality. We approach every challenge with ambition and commitment, holding ourselves and each other accountable to achieve the best results. When you join Appian, you’ll be part of a passionate team dedicated to accomplishing hard things, together. Senior Manager, Solutions Consulting Lead and develop an elite team of pre-sales engineers to architect sophisticated solutions, deliver high-impact technical demonstrations, and drive revenue velocity for Appian’s enterprise market. Location: McLean, VA | Work Model: On-site (5 days/week) About the Team The Solutions Consulting team is a high-impact corporate unit at the forefront of Appian’s global commercial engine. We bridge the gap between complex enterprise business challenges and cutting-edge technical execution. Our mission is to secure the technical win by demonstrating the undeniable value of Appian’s platform within the AI-Powered Process Automation market, driving customer acquisition and fueling global revenue growth. Under our SC 2.0 operating model , our consultants move beyond simple feature lists to tell compelling value stories and co-create digital transformation strategies. The Opportunity Enterprise organizations are facing unprecedented complexity in their digital transformation journeys, making pre-sales engineering leadership more critical than ever. As a Solutions Consulting Manager, you have a premier opportunity to lead a world-class team of technical professionals and directly shape how Fortune 500 companies automate their core operations. Operating within a structured sales incentive plan tied directly to revenue and bookings results, you will exercise significant autonomy to build system integration strategies, influence product roadmaps, and establish Appian as the gold standard for Enterprise-Grade Orchestrati

This is Adyen Adyen provides payments, data, and financial products in a single solution for customers like Meta, Uber, H&M, and Microsoft - making us the financial technology platform of choice. At Adyen, everything we do is engineered for ambition. For our teams, we create an environment with opportunities for our people to succeed, backed by the culture and support to ensure they are enabled to truly own their careers. We are motivated individuals who tackle unique technical challenges at scale and solve them as a team. Together, we deliver innovative and ethical solutions that help businesses achieve their ambitions faster. Senior Partnerships Manager - Visa Adyen is looking for a Senior Partnerships Manager who will advance Adyen’s strategy and agenda with Visa globally. In this role, you will lead high-impact Visa partnerships for Adyen and use your expertise and influence to build strong inroads across their global organization. You will serve as a recognized subject matter expert whose insights help shape our partnership strategy, while working together with a broad range of senior cross-functional stakeholders across Product, Commercial, and Finance teams. This is a full-time position based in our London or Amsterdam office reporting into our Head of Card Network & Product Partnerships. What you’ll do Strategic Partnership Management: Build and nurture deep global relationships with Visa across all levels. Architect and execute multi-year strategic plans for key initiatives and establish partnership frameworks to ensure Adyen remains at the forefront of payments innovation Deliver High-Impact Outcomes: Drive breakthrough commercial performance and long-term financial scalability for our Visa portfolio. Solve complex, ambiguous payment ecosystem challenges by leveraging deep analytical insight into scheme economics, scheme fees, and incentive structures Product Strategy & Innovation: Serve as a key strategic advisor to Product. Deeply shape

JOB TITLE: Senior Security Data Engineer CLASSIFICATION: Exempt Approved by: Jitendra Patil EXPERIENCE: 5–10 Years Approved Date: REPORTS TO: Shivendra Ashish Revised Dates: POSITIONS SUPERVISED: Core Responsibilities: Pipeline Management: Maintain high-throughput streaming pipelines to ingest logs from various sources (Firewalls, Cloud, Endpoints) to a central destination. Log Normalization: Write parsers to convert raw, messy logs into standard schemas (e.g., OCSF or ECS) for consistent querying. Cost Optimization: Implement routing logic to send "high-value" data to the SIEM and "bulk" data to low-cost Object Storage (Data Lake). Data Preparation: Clean and structure data to enable AI/ML detection models and advanced analytics. Must-Have Skills: Data Engineering: Proficiency in Python (for ETL) and SQL (for complex querying). Streaming Tech: Experience with Message Queues (e.g., Kafka, Pub/Sub) and stream processing concepts. Log Handling: Mastery of Regex and log parsing strategies for standard formats (Syslog, CEF, JSON). Storage Architecture: Understanding of Data Lake principles (Parquet/Avro formats) vs. Data Warehouses. Preferred / Nice to Have: Experience with Vector Databases for storing embeddings. Knowledge of Log Observability/Routing tools (middleware that routes logs). Familiarity with Big Data frameworks (e.g., Spark, Flink). Ability to embrace Clearwater's CLEAR core values (Commitment to Client Success, Lead with Accountability, Integrity & Collaboration, Excellence in All That We Do, Advance Colleague Success, Respect & Transparency) and culture. Disclaimer: The above statements are intended to describe the general nature and level of work being performed by people assigned to this position. They are not to be construed as an exhaustive list of all responsibilities, duties, and skills required of colleagues in the role. All colleagues may be required to perform duties outside of their normal responsibilities fr

Webflow is the agentic web marketing platform for modern marketing teams, helping organizations build, manage, and optimize high-performing web experiences that drive predictable growth and strengthen brand trust. Building at Webflow will need grit, because we move fast, without ever sacrificing craft or quality. We’re looking for a Senior Manager, AI Customer Success to help us build and lead the Customer Success team for Source by Webflow, a new platform where marketing teams and their AI agents launch, optimize and scale digital experiences together. Source is in limited research preview today, and this team will support customers as it moves into commercial availability. You’ll start as a player/coach, owning a small portfolio of strategic enterprise Source accounts, including renewals and growth. As Source adoption grows, you’ll build and scale the team. Your job is to help customers get agents into production, prove the business value, and turn that into retention and expansion. This is a first of its kind role for a first of its kind product. There is no playbook yet, and you will write it. About the role: Location: Remote-first (United States) Full-time Permanent Exempt The cash compensation for this role is tailored to align with the cost of labor in different geographic markets. We've structured the base pay ranges for this role into zones for our geographic markets, and the specific base pay within the range will be determined by the candidate’s geographic location, job-related experience, knowledge, qualifications, and skills. United States (all figures cited below are in USD and pertain to workers in the United States) Zone A: $204,000 - $255,000 Zone B: $190,000 - $238,000 Zone C: $177,500 - $222,000 For sales roles, the ranges provided are the role’s On Target Earnings (“OTE”) ranges, meaning that the ranges include both the sales commissions target and annual base salary for the role. This salary range may be inclusive of several career levels

Senior Mobile Producer (Atari) Location: Remote, Melbourne Ideal, not required. Time Zone: Australian, New Zealand, Southeast Asian, Japanese, or Korean time zones About Us Atari, one of the world's most iconic entertainment brands, is a pioneer in interactive entertainment. With operations spanning gaming, e-commerce, licensing, and hardware, Atari thrives at the intersection of innovation and legacy. Join our dynamic team and help shape the next generation of Atari games across mobile, web, and emerging platforms. About the Role Atari is seeking a highly experienced Senior Mobile Producer to lead the development, porting, and delivery of mobile and web games across a growing portfolio. You’ll work with internal stakeholders, external development and porting teams, platform partners, and strategic partners to ensure games are built correctly, tested thoroughly, and delivered on time. This is a product-focused production role, not a marketing role. You’ll take ownership across the full game development lifecycle, from identifying promising existing titles and exploring new development opportunities through production, testing, porting, platform submission, launch readiness, and ongoing product improvement. The role will have a balanced focus across porting existing titles and developing new games under Atari Mobile, with the opportunity to explore web-based games and other emerging product opportunities. You’ll manage multiple games simultaneously and bring structure, clarity, and momentum to a fast-moving portfolio. What You'll Do Own the end-to-end production lifecycle for mobile and web games, from early product exploration and concept development through production, testing, launch, and post-launch support. Manage multiple games and initiatives in parallel, maintaining clear priorities, schedules, milestones, risks, dependencies, and delivery expectations across the portfolio. Lead the porting of games to mobile and other platforms, coordina