Jobs in United States

Senior Lead Technical Program Manager Infrastructure in United States

1,941 active opportunities · Updated October 2026

Explore current senior lead technical program manager infrastructure jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

Hiring demand

43/100

watch · 145 related jobs

Hiring trend

-64.5%

Job postings compared with the previous 30 days

Remote options

20.7%

Share of matching jobs listed as remote

Typical salary

$145.7K – $145.7K/yr

Based on 9 salary observations

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📍 Santa Clara, United States
✓ Quality checkedDemand 43/100Company trend -8%

$145.7K – $148.8K/yr · Jobiba est.

NVIDIA's DGX Cloud (DGXC) powers AI for strategic research and product workloads. The company seeks a Senior Technical Program Manager (TPM) to lead complex, cross-functional programs powering NVIDIA’s next-generation AI software platforms. In this role, you will drive software initiatives across platform services, cloud infrastructure, and system integration. The focus is on enabling scalable, reliable, and supportable software for AI workloads. You will be responsible for managing high-impact engineering programs within a dynamic, fast-paced roadmap, aligning priorities across teams, and ensuring timely, high-quality delivery. This role requires strong technical competence, a proactive approach, and the ability to operate effectively across multiple levels of the organization. This is a software-first TPM role. The ideal candidate has extensive experience managing software initiatives. They also understand the full-stack environment, including infrastructure dependencies, system bring-up, integration readiness, and operational needs to support software across stack layers. What You'll Be Doing: Lead end-to-end execution of software platform initiatives, including planning, execution, delivery, and operationalization. Work together with software, infrastructure, product, and operations teams to ensure alignment on goals, deliverables, achievements, and schedules. Lead cross-functional initiatives encompassing cloud-native services, platform software, system integration, and release delivery. Help connect software roadmap execution to full-stack readiness, including dependencies across infrastructure, bring-up, validation, and downstream operational support. Identify cross-functional dependencies, mitigate risks, and drive resolution of complex technical and programmatic issues. Establish clear success metrics and reporting mechanis

KubernetesLinuxMachine LearningArtificial Intelligence
M
📍 O Fallon, Missouri, United States
✓ High-confidence listingDemand 43/100Company trend +212.5%

$145.7K – $148.8K/yr · Jobiba est.

Quick readStrong listing-quality and freshness signals

Our Purpose Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential. Title and Summary Senior Technical Program Manager Overview As a Senior Technical Program Manager at Mastercard, you’ll bring your expertise with conceptualizing, coordinating and driving technology projects, and coaching Agile practices in high-performing, self-organizing development teams. We’re building a global B2B, microservices-based platform to help businesses of all sizes streamline how they manage payments when buying or selling products & services. As a global business, the projects you lead for Mastercard will deliver software operating at massive scale requiring a focus on performance, security, and reliability. This role will support our Network Solutions team within Payment Networks, assisting the development team with building out software solutions for Mastercard. Role: • Dive as deep as you want into the tech stack, the integration patterns, the organizational capabilities, and the company wide assets that can be leveraged to provide technical solutions to customer problems. • Contribute to the strategies, design choices, and even the cloud infrastructure necessary to build comprehensive and achievable execution plans to deliver high-profile new features and capabilities for our customers. • Drive the execution of an initiative that may span multiple teams and integrations, reporting meani

AIRecruitment
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingTop 10% payDemand 43/100Company trend -100%

From $226.4K/yr

Quick readTop 10% pay versus similar roles

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. As Senior Technical Program Manager for the Human-in-the-Loop (HITL) Operations , you will own the end-to-end lifecycle of Roblox's AI data labeling and model evaluation ecosystem. This is a high-leverage, high-ownership role at the intersection of Research, Engineering, and Operations. You will scale our data operations that is handling million of items evaluated annually today with projection of 4x the current volume by 2030, managing a multi-million annual budget and a distributed workforce of 100+ remote contractors — all while driving the platform evolution from manual workflows to AI-assisted, LLM-accelerated operations. This is a rare opportunity to build the data infrastructure that directly determines the quality of Roblox's AI models across creator tools, content discovery, in-experience AI, and 3D generative content — at the exact moment when human judgment is the critical ingredient for getting these models right. You Will Lead data programs end-to-end. Own the full lifecycle of labeling and model evaluation workflows across Roblox's AI teams — from translating ambiguous ML requirements into structured annotation tasks, to overseeing contractor execution, quality review, a

PythonSQLAWSGit
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedDemand 43/100Company trend -80.2%

$145.7K – $148.8K/yr · Jobiba est.

About the Team OpenAI’s mission is to ensure that artificial general intelligence benefits all of humanity. Safely delivering increasingly capable AI systems requires scalable technical safeguards, clear ownership of emerging risks, rigorous deployment readiness, and close coordination across research, engineering, product, operations, legal, policy, and external partners. Our Technical Program Managers lead complex, high-stakes initiatives that turn safety commitments into deployed systems and measurable outcomes. We work across model development, infrastructure, product, and operational response to help ensure our technology is deployed responsibly and cannot be used to cause serious real-world harm. About the Role We’re seeking Technical Program Managers to drive complex product, platform, and safety initiatives across ChatGPT, API, enterprise, and related deployment environments. These roles operate at the intersection of technical strategy and execution: you will turn safety and product priorities into actionable plans, influence architectural and operational decisions, and deliver durable capabilities across model, infrastructure, application, and platform layers. Depending on the role, you may enable sensitive or high-impact model deployments, integrate safeguards into cloud and API platforms, prevent violent misuse and other serious harms, improve detection and enforcement systems, create platform solutions for safety or establish new programs as risks evolve. You will partner deeply with engineers, researchers, product managers, and operational teams while communicating technical tradeoffs and program decisions to senior leadership. You bring technical fluency, product judgment, and a strong execution record. You’re comfortable navigating ambiguity, advocating for users and developers, balancing safety with model usefulness, and leading cross-functional work with urgency, rigor, and empathy. Specific focus areas and scope will vary by opening and level. Thi

AWSRestMachine LearningAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedDemand 43/100Company trend -80.2%

$145.7K – $148.8K/yr · Jobiba est.

About the Team The Product & Platform teams at OpenAI are responsible for delivering the company’s most impactful offerings—such as ChatGPT, our API platform, and new enterprise capabilities—to a global and diverse customer base. These systems must perform at scale and deliver exceptional experiences to developers, consumers, and businesses alike. Technical Program Managers at OpenAI play a key leadership role in scaling these efforts, partnering deeply with product, engineering, design, and go-to-market teams to bring ambitious ideas to life and ensure clarity and discipline in execution. About the Role We are hiring a Technical Program Manager to support OpenAI's critical AI deployments across strategic cloud partners. This role is designed for a candidate who can operate as an end-to-end owner across internal engineering teams and external partner organizations. This role will drive the technical strategy and execution required to bring OpenAI models and platform capabilities into partner environments responsibly and at scale. The work spans engineering deliverables, shared roadmaps, model launch pipelines, technical integration, launch readiness, and post-launch follow-through. You will work closely with senior leaders across OpenAI engineering, infrastructure, product, safety, security, legal, finance, and go-to-market, as well as technical counterparts at our partners. The job is to turn broad partnership commitments into concrete execution plans, align both sides on what must land, and build repeatable mechanisms for launching OpenAI capabilities on third-party platforms. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Lead end-to-end execution for major cloud partner programs spanning model deployment, product integration, operational readiness, launch follow-through, and partner-platform adoption. Own integrated technical roadma

AWSRestAIGo
A
📍 United States· Full-time
✓ High-confidence listingCompany trend -98.8%

From $232K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: Airbnb's mission is to create a world where people can Belong Anywhere. As we grow to achieve that mission, we're looking to add a technical, hands-on, and mission-driven Senior Manager of Technical Program Management (TPM) for the Infrastructure team to lead AI Platforms initiatives spanning Search Relevance, Machine Learning Infrastructure (MLI), and Search Knowledge Infrastructure (SKI). This person will partner with our engineering & product teams to build/enhance data-driven decision making across multiple areas in Airbnb. They will partner closely with senior ICs and engineering directors across Airbnb on processes, strategy and execution. In this role, you will collaborate closely with the Machine Learning (ML) engineers, infrastructure engineers and product managers from across Airbnb to develop holistic solutions that ensure a vibrant and equitable marketplace. The Search Relevance, Machine Learning Infrastructure (MLI), and Search Knowledge Infrastructure (SKI) teams power the ranking, recommendations, model infrastructure, and search intelligence capabilities that make up a core part of Airbnb's AI Platforms, including: Search Ranking for Stays, Experiences, and Services, Home Page Recommendations, Search Bar AutoSuggest and Autocomplete, Marketing Technology, and the ML infrastructure and platform capabilities that support them. The team also creates the fabric for personalization and the underlying model infrastructure, used both on and off platform for Airbnb. We collaborate with many teams including Search Infrastructure, Guest and Host Experiences, MD

Machine LearningAIGoRust
V
📍 United States· Full-time
✓ Quality checkedCompany trend -88.6%

At Vanta, our mission is to help businesses earn and prove trust. We believe that security should be monitored and verified continuously, and we empower companies to practice better security and prove it with ease. Vanta has a kind and talented team, and while some have prior security experience, many have been successful at Vanta without it. Vanta's Corporate Engineering team is the infrastructure layer that keeps 1,500+ people connected, secure, and moving fast. AI is now central to how that happens, and this role leads the team that owns the backbone underneath it. Corporate Engineering owns the shared AI platform for Vanta's internal systems: identity and access for AI tools, cost visibility and controls, sanctioned tooling and guardrails, and the enablement that helps people use those tools well. We do not own product AI, which stays with Engineering, and we do not replace the AI work happening inside individual departments. We build the engineering layer that makes all of it safer, cheaper, and better supported. The company has moved fast. AI assistant use is widespread across every function, MCP infrastructure is live and self-serve company-wide, internal apps ship on a hosted platform, and AI spend has grown to the point where attribution and guardrails genuinely matter. What does not exist yet is a single owner for that platform layer. That is this role. As Sr. Manager, AI Engineering, you will lead a small, senior team, write the charter for what Corporate Engineering owns versus enables, and build the platform that lets the rest of Vanta adopt AI quickly without accumulating cost, risk, or duplication. What you’ll do as a Senior Manager, AI Corporate Engineering at Vanta: Lead, coach, and grow a senior team spanning platform engineering and technical program management. Set clear direction, hold a high bar, and give the team explicit permission to push back with data. Own the AI access layer end to end: identity and authentication for AI tools, connector

CI/CDRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team Tax and Trade at OpenAI shapes business strategy by embedding critical tax, export control, customs, and cross-border considerations into how the company builds, sources, scales, and operates in support of the mission. We combine deep expertise with practical systems thinking to look around corners, identify emerging risks and opportunities early, and help teams make smarter decisions at the point where strategy becomes execution. Across procurement, hardware operations, manufacturing, logistics, finance, legal, supplier onboarding, and operator workflows, we build robust, scalable support services leveraging cutting-edge technology—including governed AI and automation—to make complex regulated work more durable, more efficient, and easier to scale. About the Role We’re hiring a Senior Manager, Export Controls to lead OpenAI’s export controls strategy and operating model. This is a senior role with broad scope across advanced computing, semiconductors, software, hardware, manufacturing, and high technology partnerships. You will refine how OpenAI classifies controlled technology, software, and hardware, structures access-controlled environments, manages licensing and supplier commitments, and scales export-control operations in a way that supports the company’s pace of innovation. You will also shape how OpenAI applies AI and agentic workflows to policy-heavy operational work, building systems that make complex rules easier to navigate and easier to execute. In this role, you will: Refine the strategy and operating model for OpenAI’s export controls program across advanced computing, semiconductors, software, hardware, manufacturing, and high technology partnerships. Own export classification and licensing strategy for controlled technical data, software, hardware, and research environments. Lead the design and operation of compliant controlled environments and related governance processes. Partner with Research and Infrastructure to support efficient

AWSRestAIGo
B
📍 Berkeley, United States
✓ Quality checkedCompany trend +515.8%

Cloud Infrastructure Administrator (Mid-Level, Senior or Lead) **Sign on Bonus Potential** Company: The Boeing Company The Boeing Company’s Specialized United States Infrastructure Operations organization is currently seeking a Cloud Infrastructure Administrator (Mid-Level, Senior or Lead) to join the team in Berkeley, MO; Seattle, WA; or Daytona Beach, FL . The Infrastructure team is seeking an experienced cloud infrastructure professional to help design, build, and sustain the foundational cloud environment supporting critical program needs. In this role, the selected candidate will help establish and operate secure, scalable, and resilient cloud infrastructure environments in Microsoft Azure to enable enterprise applications, software toolchains, and digital engineering workloads. As both an individual contributor and technical leader, this position will work across network, computer, storage, identity, security, and automation domains to deliver repeatable cloud infrastructure patterns and operational excellence. This role is focused on infrastructure operations, sustainment, automation, and reliability, rather than application software development. Position Responsibilities: Design, implement, and maintain Microsoft Azure-based infrastructure solutions including networking, compute, storage, identity integration, and supporting services Develop and maintain Infrastructure as Code (IaC) and configuration automation solutions using Terraform, Ansible, PowerShell, and Bash Implement cloud policies to enforce security, ensure regulatory compliance, and manage user access Build repeatable landing zones and cloud infrastructure patterns that support mul

AzureTerraformAnsibleSap
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Role We are looking for a senior partner success and learning professional to activate cloud partners to co-sell and deploy customer solutions at scale. This role leads the enablement strategy and execution that equip partner teams to turn joint priorities into measurable customer and business outcomes. As a trusted advisor to strategic partners, you will turn shared business priorities into practical enablement programs that help partner sales, technical, customer success, and leadership teams identify joint opportunities, co-sell effectively, and deploy customer solutions successfully. You will own the partner enablement relationship for an assigned portfolio and work across internal teams to ensure programs are coordinated, scalable, and connected to measurable partner, customer, and business outcomes. This is not a traditional training delivery role or a quota-carrying partner account manager position. It is a consultative, partner-facing role for someone who can shape strategy, build relationships, translate complex AI capabilities into effective learning experiences, lead persuasive enablement sessions, and guide strategic partners toward sustained success. In this role, you will: Own strategic partner enablement and success Serve as the primary enablement and success lead for a portfolio of strategic cloud platforms. Develop a deep understanding of each partner’s business, priorities, audiences, existing learning infrastructure, and strategic relationship with our company. Build partner-specific enablement strategies aligned to shared goals, priorities, and the broader partnership strategy. Establish trusted relationships with partner leaders, alliance teams, enablement stakeholders, sales organizations, technical communities, and post-sales teams. Lead ongoing planning conversations, enablement reviews, stakeholder check-ins, and executive updates that keep partners and internal teams aligned. Identify gaps, risks, opportunities, and emerging partn

AWSRestMachine LearningAI
P
📍 Pennsylvania, United States
✓ High-confidence listingCompany trend +671.4%

$99.2K – $165.4K/yr

Quick readStrong listing-quality and freshness signals

Role Summary The CISO, Infrastructure and Cloud Services organization enables Pfizer’s mission by delivering secure, resilient, and scalable technology platforms that support operations and future growth. Through a unified operating model, it strengthens accountability, accelerates decision‑making, and improves availability, security, and cost efficiency. The CISO Marketing Manager will support the Senior Manager, Marketing and Enterprise Awareness to develop meaningful marketing materials that tell the CISO story to external clients by executing strategic, creative, and visually compelling communications including presentations, graphics, pictures, charts and tables that support cybersecurity awareness, organizational priorities, and business outcomes. The manager will lead the creation of a marketing strategy for the Chief Information Security Office Team. Role Responsibilities Lead the development and execution of integrated marketing and communications strategies in support of CISO priorities, strategic initiatives, and portfolio management objectives. Produce high-quality written, visual, and digital content that strengthens awareness, engagement, and understanding of cybersecurity programs across the organization. Create and manage internal communications, including newsletters, leadership messages, campaign materials, SharePoint content, presentations, infographics, and other digital assets. Simplify complex cybersecurity and technical information into clear, engaging, and actionable content for diverse audiences, including executives, business partners, and internal colleagues. Partner closely with cross-functional teams across Cyber Defense, Infrastructure, Cloud, and related Digital and Technology groups to ensure consistent, coordinated, and impactful messaging. Develop executive-ready presentations and visual storytelling materials

AIExcelRecruitment
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $295.3K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. Join Roblox as an Engineering Manager of Application Security and lead a team responsible for improving the security of our products, services, and development ecosystem. In this role, you will drive security across the software lifecycle, partnering with engineering teams to identify risks, improve secure development practices, and build scalable solutions that protect Roblox at scale. You will balance hands-on security work with longer-term investments in automation, tooling, and developer enablement. You will work closely with engineering, infrastructure, and security teams to reduce risk while enabling teams to move quickly and safely. This role reports to the Senior Manager of Application Security and is based in San Mateo with a hybrid schedule. You Have: 8+ years of experience in Information Security 2+ years of experience managing engineers Strong background in Application Security or Product Security Experience driving security programs across the software development lifecycle Solid understanding of common vulnerabilities (e.g., OWASP Top 10) and secure coding practices Experience working closely with engineering teams in modern environments (cloud, microservices, CI/CD) Prov

AWSCI/CDGitMicroservices
R
📍 Foster City, California, United States· Full-time
✓ Quality checkedCompany trend -85.9%

Replit is the agentic software creation platform that enables anyone to build applications using natural language. With millions of users worldwide, Replit is democratizing software development by removing traditional barriers to application creation. About the role: As a Staff Product Engineer at Replit, you’ll work closely with other product and platform engineers, designers, sales representative, and product managers to build features that help users collaborate with their team to go from idea to software fast. You’ll be at the forefront of shaping and experimenting on what our tens of millions of users love. You will: Help lead major projects and take new products from 0->1 Identify the hardest technical and/or quality problems holding us back, and then build solutions Chart high level technical direction and follow up to make sure those projects come together to deliver on results Mentor and develop new senior engineers to help grow the team Ship new features and build infrastructure using: TypeScript, React, CSS, GraphQL, Node.js, and Postgres Required skills and experience: A minimum of 7 years of professional software development experience Experience in a technical leadership role, working cross functionally Working experience building full stack applications with TypeScript Working experience building directly for users Bonus Points : You’re excited about the future of programming and have experience working with IDEs, terminals, or other common developer tools You’ve had previous experience working at a startup in a cross-functional engineering role This is a full-time role that can be held from our Foster City, CA office. The hybrid role has an in-office requirement of Monday, Wednesday, and Friday. Full-Time Employee Benefits Include: 💰 Competitive Salary & Equity 💹 401(k) Program with a 4% match ( US Only ) ⚕️ Health, Dental, Vision and Life Insurance 🩼 Short Term and Long Term Disability 🚼 Paid Parental, Medical, Caregiver Leave 🏝 Flexible

TypeScriptReactNode.jsGraphql
A
📍 San Francisco, United States· Full-time
✓ High-confidence listingCompany trend -98.8%

From $204K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: The Total Rewards Compensation team serves as a strategic advisor to business leaders, managers, and employees across Airbnb. We are compensation experts with a deep understanding of our stakeholders, problem solvers who use data and insights to drive value, and partners who build the tools, models, and frameworks that support sound compensation decision-making across the company. This role sits within the Compensation function and will work closely with the Technology organization and cross-functional partners including Talent Directors, Recruiting, People Analytics, Finance, and Legal. The Difference You Will Make: We are looking for a Senior Compensation Partner to own Airbnb's compensation strategy for the Technology organization, covering functions such as Engineering, Infrastructure, ML/AI and Data Science. You will be the primary Total Rewards advisor to Technology leadership and the compensation point of contact for Talent Directors and Recruiting, defining how Airbnb competes for AI, ML, and frontier engineering talent. Working alongside our regional Total Rewards Partners, you will hold a global view of how we pay technical talent across all markets. Beyond your client group, you will contribute to the design and strategy of complex global programs, lead core Total Rewards priorities, and build the models and tools the broader Compensation team relies on. You are equally credible advising our most senior technical leaders and in the data behind the recommendation. A Typical Day: Serve as the senior compensation advisor to Technology leadership across func

PythonSQLAIGo
T
📍 Austin, Texas, United States· Full-time
✓ High-confidence listingTop 10% payDemand 43/100

$100K – $500K/yr

Quick readTop 10% pay versus similar roles

Tenstorrent is leading the industry on cutting-edge AI technology, revolutionizing performance expectations, ease of use, and cost efficiency. With AI redefining the computing paradigm, solutions must evolve to unify innovations in software models, compilers, platforms, networking, and semiconductors. Our diverse team of technologists have developed a high performance RISC-V CPU from scratch, and share a passion for AI and a deep desire to build the best AI platform possible. We value collaboration, curiosity, and a commitment to solving hard problems. We are growing our team and looking for contributors of all seniorities. We're looking for an Engineering Program Manager — or a technical engineer ready to move into program management — to help drive execution on our RISC-V CPU team. You'll work across architecture, design, verification, physical design, and DFT to keep a high-performance CPU program moving from spec through tapeout and post-silicon debug. Partnering with a senior program lead and engineering managers, you'll own schedules, track milestones, surface risks early, and keep cross-functional teams aligned. This role is hybrid, based out of Austin, TX or Santa Clara, CA. We welcome candidates at various experience levels for this role. During the interview process, candidates will be assessed for the appropriate level, and offers will align with that level, which may differ from the one in this posting. Who You Are Experience in CPU, SoC, or silicon development — as an engineer, technical lead, or program manager. Comfortable working with cross-functional engineering teams and translating technical detail into clear status, dependencies, and trade-offs. Organized and proactive; you chase down open items rather than waiting for them to resolve. A clear communicator who can hold your own in engineering discussions and write updates leadership can act on. What We Need Support the full CPU development cycle — spec, design, verification, DFT, ta

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