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Senior Principal Model Optimization Engineer Jobs

10,000 active opportunities · Updated for October 2026

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Explore current senior principal model optimization engineer jobs. Use filters to narrow by work mode, employment type, experience and date posted.

T
6mo ago

Who we are At Twilio, we’re shaping the future of communications, all from the comfort of our homes. We deliver innovative solutions to hundreds of thousands of businesses and empower millions of developers worldwide to craft personalized customer experiences. Our dedication to remote-first work , and strong culture of connection and global inclusion means that no matter your location, you’re part of a vibrant team with diverse experiences making a global impact each day. As we continue to revolutionize how the world interacts, we’re acquiring new skills and experiences that make work feel truly rewarding. Your career at Twilio is in your hands. . Hiring and how we work We use Artificial Intelligence (AI) to help make our hiring process efficient. That said, every hiring decision is made by real Twilions! Also, while we are a remote-first company, you may be asked to report in person on an ad-hoc basis for team gatherings, functional off-sites or customer meetings. . See yourself at Twilio Join the team as Twilio’s next Senior Principal, Technical Program Management within Research & Development (R&D). About the job Twilio is the world’s leading customer engagement platform empowering developers to build modern communication applications and experiences designed to be trusted, simple and smart. Twilio is looking for a Senior Principal Technical Program Manager to help direct a portfolio of strategic, complex, and multidisciplinary programs that significantly accelerate R&D's business impact. You'll set program strategy and lead program teams to successfully deliver business, operational, and technical improvements across Engineering & Product organizations. As a trusted strategic advisor, you will play a critical role in driving alignment, setting priorities, and delivering high-impact programs that advance strategic initiatives. The Senior Principal, Technical Program Management is highly visible and require

REMOTErestagileai
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R
Roblox
📍 San Mateo• $345K – $399.4K/yr
7mo ago

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. As a Principal Software Engineer on Creator Services Data, you’ll be leading the company’s efforts to build the next generation Data Storage systems to power the millions of experiences on the Roblox Platform. We run the mission critical cloud services, Data Stores , Memory Stores , and Badges , which are crucial for storing game state such as inventory and scores, implementing leaderboards, server lists, and trading, and tracking player progress and achievements. Our team is also responsible for building dashboards to provide insights to Creators using cloud services including Client/Server Performance , Data Stores , and Memory Stores . Finally, our team owns the Roblox Extended Services platform, which provides the capability for large experiences to purchase additional resources for existing services like Data Stores and new services built around compute and generative AI. At its core, this team is focused on solving complex back end distributed systems and storage problems at scale. However, our scope extends to full stack projects spanning all the way from the infrastructure layer, through data storage and data pipelines, microservices, telemetry, game servers,

awsazuregcp
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Who We Are At OKX, we believe that the future will be reshaped by crypto, and ultimately contribute to every individual's freedom. OKX is a leading crypto exchange, and the developer of OKX Wallet, giving millions access to crypto trading and decentralized crypto applications (dApps). OKX is also a trusted brand by hundreds of large institutions seeking access to crypto markets. We are safe and reliable, backed by our Proof of Reserves. Across our multiple offices globally, we are united by our core principles: We Before Me , Do the Right Thing , and Get Things Done . These shared values drive our culture, shape our processes, and foster a friendly, rewarding, and diverse environment for every OK-er. OKX is part of OKG, a group that brings the value of Blockchain to users around the world, through our leading products OKX, OKX Wallet, OKLink and more. About the Opportunity What You’ll Be Doing Own product strategy and roadmap for the DEX Trading product, covering Token Market, Swap (Aggregator), Bridge, Limit Order, and emerging trading primitives. Partner closely with the Growth & Operations team to ship initiatives that drive user acquisition, activation, retention, and trading volume, turning growth hypotheses into PRDs, prototypes, and launched features. Identify and prototype new product opportunities in DEX, evaluating emerging protocols, narratives, and paradigms (intent-based trading, MEV protection, new L1/L2s, etc.) with AI-augmented research and competitive scanning to move faster and broader than manual analysis allows. Lead end-to-end execution: drive PRDs, prototypes, and supporting documentation with AI in the loop for higher velocity and quality, then partner with R&D, UI/UX, QA, and Marketing through to launch. Define, instrument, and monitor core product KPIs (Volume, MAU, retention, route quality, etc.); run your own data analysis with AI-assisted SQL , exploratory queries, and insight synthesi

sqlairecruitment
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Who We Are At OKX, we believe that the future will be reshaped by crypto, and ultimately contribute to every individual's freedom. OKX is a leading crypto exchange, and the developer of OKX Wallet, giving millions access to crypto trading and decentralized crypto applications (dApps). OKX is also a trusted brand by hundreds of large institutions seeking access to crypto markets. We are safe and reliable, backed by our Proof of Reserves. Across our multiple offices globally, we are united by our core principles: We Before Me , Do the Right Thing , and Get Things Done . These shared values drive our culture, shape our processes, and foster a friendly, rewarding, and diverse environment for every OK-er. OKX is part of OKG, a group that brings the value of Blockchain to users around the world, through our leading products OKX, OKX Wallet, OKLink and more. About the Opportunity What You’ll Be Doing Own product strategy and roadmap for the DEX Trading product, covering Token Market, Swap (Aggregator), Bridge, Limit Order, and emerging trading primitives. Partner closely with the Growth & Operations team to ship initiatives that drive user acquisition, activation, retention, and trading volume, turning growth hypotheses into PRDs, prototypes, and launched features. Identify and prototype new product opportunities in DEX, evaluating emerging protocols, narratives, and paradigms (intent-based trading, MEV protection, new L1/L2s, etc.) with AI-augmented research and competitive scanning to move faster and broader than manual analysis allows. Lead end-to-end execution: drive PRDs, prototypes, and supporting documentation with AI in the loop for higher velocity and quality, then partner with R&D, UI/UX, QA, and Marketing through to launch. Define, instrument, and monitor core product KPIs (Volume, MAU, retention, route quality, etc.); run your own data analysis with&

sqlairecruitment
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Strength in Trust OneTrust’s mission is to enable innovation through the responsible use of data and AI. We believe that ensuring data is trusted shouldn’t slow teams down—it should accelerate what’s possible. This led us to develop the first technology platform for responsible data use in 2016. Today, with AI representing the latest and most impactful expansion of data yet, OneTrust is once again redefining what responsible innovation looks like. OneTrust, the AI‑Ready Governance Platform™, unifies regulatory intelligence, automation, and connected governance workflows so businesses can continue to move at the speed of AI while ensuring good governance to prevent data misuse at scale. Trusted by thousands of organizations worldwide, OneTrust is shaping the future where trusted data becomes a transformative force for business and society. The Challenge We are looking for a Principal Solutions Engineer to lead the technical strategy behind our most complex AI and data governance opportunities. You will work directly with enterprise customers to design how they govern AI and data in practice, not just in policy. You will lead high-impact deals, influence executive stakeholders, and help position OneTrust as a leader in AI governance. At the same time, you will help raise the level of the entire Solutions Engineering organisation by building repeatable approaches that scale beyond our own deals. Your Mission Own technical strategy in complex, multi-stakeholder enterprise deals and partner closely with Account Executives to drive deal progression and win outcomes Engage senior stakeholders including CIO, CISO, AI, Risk, and Data leaders in high-impact conversations Design end-to-end AI and data governance solutions, translating fragmented requirements and regulatory expectations into scalable architectures and workflows Lead deep discovery, clearly position against alternatives, and deliver POCs tha

airecruitment
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G
7mo ago

About us Graphcore is one of the world’s leading innovators in Artificial Intelligence compute. It is developing hardware, software and systems infrastructure that will unlock the next generation of AI breakthroughs and power the widespread adoption of AI solutions across every industry. As part of the SoftBank Group, Graphcore is a member of an elite family of companies responsible for some of the world’s most transformative technologies. Together, they share a bold vision: to enable Artificial Super Intelligence and ensure its benefits are accessible to everyone. Graphcore’s teams are drawn from diverse backgrounds and bring a broad range of skills and perspectives. A melting pot of AI research specialists, silicon designers, software engineers and systems architects, Graphcore enjoys a culture of continuous learning and constant innovation. Job Summary We are seeking a Senior Principal Network Engineer to help design, deploy, and optimize next‑generation AI data center networks. AI training and inference workloads require extremely high bandwidth, deterministic low latency, and zero‑packet‑loss networking environments. In this role, you will partner closely with the Network Architecture Lead to design and scale high‑performance computing (HPC) network fabrics supporting GPU clusters. You will work across hardware, networking, and AI application layers to ensure Graphcore’s large‑scale AI infrastructure operates at peak performance. The ideal candidate brings deep experience operating hyperscale or HPC data center networks and has expertise in high‑speed Ethernet fabrics, RDMA technologies, advanced automation, and telemetry systems. The Team The Data Center Network Engineering team designs and operates the high‑performance network fabrics that power Graphcore’s AI compute platforms. The team collaborates closely with hardware engineering, AI researchers, and infrastructure teams to build scalable networking environments optimized for distributed training and infe

pythonartificial intelligenceai
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C
11mo ago

Our Product Management team drives product initiatives from inception through execution, makes impacts and launches products/features across our global footprint. We collaborate closely with engineers, designers, analysts, marketers, and other cross-functional team members to ship remarkable features and products. Role Overview We are looking for a Senior Product Manager, Trading to own trading products on the Crypto.com App end-to-end. Retail trading is where users feel the product every day - and where volume, engagement, and retention compound. Every improvement you ship shows up in how people trade, how often they come back, and how Crypto.com wins share in a crowded market. Your mandate is to drive trading products from discovery through launch and iteration: roadmap clarity, feature definition, customer insight, and shipping at global scale. You will run your roadmap with independence within Trading's strategic priorities. You prioritize initiatives, cut tradeoffs, and make the call on what ships when. You report to the Senior Director of Product Management, who sets strategic direction. You own the how and the when. If you've shipped trading or financial products at scale, this will feel familiar. The difference is you'll be doing it at the frontier of crypto retail trading- perpetuals, spot, and adjacent markets- where the rails keep moving and the playbook is yours to write. No layers. No politics. What You'll Actually Do: Own the Trading roadmap. You set milestones, surface dependencies, and keep strategic priorities honest. You make the prioritization call when everything can't ship at once. Define and ship trading experiences. You write the specs, run user studies, iterate on feedback, partner with QA on test plans, and clear the backlog. Nothing in your charter goes live without your sign-off. Stay close to how traders actually behave. You interview and observe customers. You ask "Show me how you currently

airecruitment
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Zscaler (NASDAQ: ZS) accelerates digital transformation so customers can be more agile, efficient, resilient, and secure. The Zscaler Zero Trust Exchange platform protects thousands of customers from cyberattacks and data loss by securely connecting users, devices, and applications in any location. Distributed across 200+ public data centers globally and thousands of private sites at the edge, the SASE-based Zero Trust Exchange is the world’s largest in-line cloud security platform. We believe the future of work is Human + AI and are building an AI-native enterprise where human potential is amplified by machine intelligence to solve the world’s hardest security challenges. Driven by deep customer obsession, we are committed to the mission, outcome, and to each other. We bring these commitments to life through three core behaviors: ownership and collaboration, trust through outcomes and impact, and a challenge culture with ongoing feedback. Ready to make an impact at the company pioneering security transformation in the AI era? Join us at Zscaler. Role We are looking for an Architect / Senior Principal Software Development Engineer (Layer 7 Security & Proxy) to join our team. This is a hybrid role (minimum 3 days a week in Santa Clara, CA office), reporting to the Director, Software Development Engineering in the Zero Trust Exchange department. This architect role is essential to provide technical leadership for the ZIA proxy architecture, with a strong focus on advanced Layer 7 protocols and SSL inspection. You will help improve the quality of code shipped to production by driving sound architectural decisions, implementing innovative solutions, and raising the overall engineering bar for the team. Additionally, you will play a key role in modernizing the ZIA code base by addressing technical debt, fixing existing issues, and rewriting components where necessary. Ultimately, this role is critical for supporting and accelerating the delivery of key proxy roadmap

Graphcore Senior Principal AI SoC Validation (Bring-up lead) Graphcore is a globally recognised leader in Artificial Intelligence computing systems. The company designs advanced semiconductors and data centre hardware that provide the specialised processing power needed to drive AI innovation, while delivering the efficiency required to support its broader adoption. As part of the SoftBank Group, Graphcore is a member of an elite family of companies responsible for some of the world’s most transformative technologies. We are opening a new AI Engineering Campus in Bengaluru which will play a central role in Graphcore's work building the future of AI computing. We are developing the next generation of AI compute, a large-scale system-on-chip (SoC) designed to power future high-performance AI systems. As the SoC Validation Lead, you will be responsible for enabling pre-production software to run reliably on new silicon quickly and efficiently, before showing that the silicon meets the highest standards of quality, reliability and functionality, ready for production deployment. You will lead a team delivering post-silicon validation across the full AI SoC, working across silicon, firmware, and platform levels. The role requires a deep technical understanding, strong hands-on debug experience, and the ability to collaborate effectively with hardware, software, and systems engineering teams. Key responsibilities Define and lead post-silicon validation strategy Develop and refine the overall post-silicon validation approach for our AI SoCs, ensuring reliable and timely delivery of validated silicon, architectural correctness, feature robustness, and at-scale system reliability. Drive cross-domain debug and issue resolution Lead investigation and resolution of complex issues spanning silicon, firmware, operating systems, and platform interactions. Ensure that fixes are effective and sustainable. Promote collaboration and shared understanding Work closely with

pythonlinuxartificial intelligence
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ClinChoice is a global full-service CRO committed to professional growth and a quality-driven “one-team” culture. We are seeking a Senior/ Principal Statistician to join our in-house team and support projects across a diverse client portfolio, including pharmaceutical, biotechnology, medical device, and consumer health companies of varying sizes. We are seeking an experienced Senior/Principal Statistician Consultant to provide statistical leadership and expertise across clinical development programs within the pharmaceutical industry. The successful candidate will contribute to clinical trial design, statistical methodology, data analysis, and regulatory submissions while collaborating with cross-functional teams to support evidence generation and informed decision-making throughout drug development. Key Responsibilities Provide statistical leadership across clinical development programs, from early-phase studies through late-phase clinical trials. Lead clinical trial design, including endpoint selection, sample size calculations, power analyses, and randomization strategies. Develop and review clinical study protocols, statistical analysis plans (SAPs), and other statistical documentation. Oversee statistical analyses and interpretation of clinical trial data to ensure scientific rigor and regulatory compliance. Provide statistical expertise for regulatory submissions and interactions with health authorities, including the FDA and EMA. Collaborate with Clinical Development, Clinical Operations, Data Management, Regulatory Affairs, and Medical Writing teams. Review statistical outputs, including tables, listings, and figures (TLFs), to ensure accuracy and consistency with analysis plans. Apply appropriate statistical methodologies to address complex clinical trial design and analysis challenges. Contribute to clinical study reports (CSRs), integrated summaries of safety and efficacy, and other regulatory documents. Identify statistical risks and recommend appropriat

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