Jobs in United States

Ai Oncology Portfolio Lead in United States

5,082 active opportunities · Updated October 2026

Explore current ai oncology portfolio lead jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $176.5K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. Roblox is building the future of human connection through play. As a Senior Growth Marketing Manager, you will play a critical role in scaling Roblox's global growth engine, helping millions of users discover, engage with, and return to Roblox. This role sits at the intersection of marketing, product, data science, and engineering. You will lead high-impact growth initiatives spanning user acquisition, lifecycle marketing, personalization, creator growth, and product-led growth. You will be responsible for identifying new growth opportunities, designing and executing experiments, influencing product strategy, and scaling programs that drive measurable business impact. This is a highly cross-functional role for someone who combines analytical rigor, strong growth instincts, operational excellence, and the ability to influence across teams. You will report to Sr Manager, Growth Marketing. You will: Own and Scale Growth Programs Lead end-to-end growth initiatives across user acquisition, reactivation, paid influencer, and product-led growth programs. Manage and optimize multimillion-dollar marketing investments across ad platforms including but not limited to Google, YouTube, Meta, TikTok, App

ReactSQLAWSGit
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $263.7K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. WHY DATA SCIENCE & ANALYTICS? The Data Science & Analytics organization's mission is to increase our speed, frequency and acumen of making decisions at scale by instilling a data-influenced approach to building products. We cover a wide area of the data spectrum including analytical data engineering, product analytics, experimentation, causal inference, statistical modeling and machine learning. Aligned and partnering with product groups, we use this vast tool belt to discover new opportunities and unmet use cases, influence and shape the product roadmap and prioritization, build data products and measure the impact on our community of players and developers. WHY CONSUMER FRONTEND? Consumer Frontend’s team mission is to deliver the frontend architecture, components, libraries, navigation patterns, and core UI necessary for a high-quality, performant, intuitive, and observable consumer user experience for gaming and all future use cases. One of the focus areas is UX Excellence through Standardization, where the goal is to maintain a comprehensive library of high-quality components and navigation patterns that ensure a consistent and intuitive experience across all consumer surfaces.

PythonSQLAWSGit
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%
Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. As a Senior Frontend Software Engineer on the Marketplace team, you will architect and scale the applications powering Roblox's Avatar Marketplace—the core digital storefront driving one of the largest virtual economies globally. This ecosystem facilitates self-expression for hundreds of millions of monthly active users and manages a catalog of hundreds of millions of items, serving as a primary revenue engine for both Roblox and our global community of User-Generated Content (UGC) creators. This is a high-leverage, high-impact role where you will design, build, and optimize cross-platform UI/UX across iOS, Android, Xbox, and cutting-edge VR platforms. If you are an expert at developing user facing applications and are passionate about user experience, you will be right at home with us! You will: Own high-traffic, mission-critical surfaces visited by millions of users daily. Your code will directly influence user engagement, retention and bookings. Architect and build marketplace experiences that drive discovery and monetization for a booming ecosystem of independent creators and brands. Partner with Product, Design and Data Science teams to run A/B tests, analyze user interactions, a

ReactAWSGitAI
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $196.8K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. As a Senior Security Engineer on the Detection and Response (D&R) team at Roblox, you’ll protect our user community alongside the underlying platform infrastructure. You’ll design high-fidelity detections, engineer security data platforms, and respond alongside the team during incidents. This is a hybrid in-office role in San Mateo. You Will: Deliver robust D&R capabilities: Engineer high-fidelity detections end-to-end. Lead partners through threat modeling and logging, to deploying actionable alerts, while keeping false positives low. Build security data pipelines: Develop security data pipelines and actively contribute to internal software and data platforms, collaborating across engineering teams. Ensure service reliability: Participate in an on-call rotation to keep detection and response services healthy. Embody security culture: Serve as a trusted security partner across Roblox, helping protect our community and enterprise while fostering a culture grounded in trust, ownership, and shared responsibility. You Have: 3+ years of experience in Security Data Engineering: You have built services that are efficient, reliable, and scalable using programming languages like Golang or Py

PythonSQLAWSGit
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $345K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. The mission of the search and discovery team is to connect a billion users with the best connections and content at the right time, covering an extremely diverse range of recommendations and search problems at high scale. This is fundamental to how we personalize the experience to drive engagement and retention for Roblox users. Our recommendation systems suggest all games that the users see and play with across all surfaces. As a Senior Engineering Manager for the Search & Discovery ML team, you will lead the architects of exploration for one of the world's largest immersive platforms. You will be responsible for the core algorithms that connect over 120 million daily active users with millions of 3D experiences, items, and social connections. This is a high-impact leadership role where your team’s models directly determine the growth, retention, and satisfaction of the Roblox community. You will move beyond traditional recommendation systems into the realm of multimodal, agentic, and generative discovery . You Will: Lead and grow a high-performing team of machine learning engineers, fostering a culture of ownership, collaboration, and engineering excellence. Establish a lo

AWSGitMachine LearningAI
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $221.4K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. WHY DATA SCIENCE & ANALYTICS? The Data Science & Analytics organization’s mission is to increase our speed, frequency and acumen of making decisions at scale by instilling a data-influenced approach to building products. We cover a wide area of the data spectrum including analytical data engineering, product analytics, experimentation, causal inference, statistical modeling and machine learning. Aligned and partnering with product verticals, we use this extensive toolbelt to discover new opportunities and unmet use cases, influence and shape the product roadmap and prioritization, build data products and measure impact on our community of players and creators. WHY CREATOR SERVICES? At Roblox, the Creator Services team enables unbounded creation through reliable core services and novel AI applications. As a Senior Data Scientist focused on Machine Intelligence , you will bridge the gap between high-tier engineering infrastructure and cutting-edge ML applications. You will be the primary strategic partner to product and engineering leadership, transforming unstructured data into actionable business insights and user-facing products. This is a "zero-to-one" environment. You will be tas

AWSGitMachine LearningAI
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $174.1K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. As a Senior Child Safety Intelligence Analyst on Roblox’s Safety Intelligence Team, you will be on the front lines protecting the platform’s youngest and most vulnerable users. This is a proactive intelligence role focused on identifying, tracking, and disrupting systemic threats to minors, to include child sexual exploitation and abuse (CSAE), grooming behaviors, peer-to-peer harassment, financial minor extortion (sextortion) and bad-actor networks trying to exploit platform features to victimize minors. You will blend quantitative and qualitative data, open-source intelligence (OSINT), behavioral analysis, and deep knowledge of online culture to uncover adversarial trends before they impact the platform ecosystem, and provide your analysis to teams across Roblox and company leadership. Your insights will directly shape automated detection logic, product safety features, and platform policy. Psychological Wellness Note: This role involves exposure to highly sensitive and potentially disturbing themes regarding the exploitation of minors. Roblox offers resources to support employees handling this challenging work. This role is based in San Mateo, CA and requires employees

PythonSQLAWSGit
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $243.3K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. As a Senior Frontend Engineer on the Voice Communication team, you'll help build how tens of millions of people talk to each other on Roblox. Voice is one of our most important levers for deeper social connection, and you'll shape the client experience that makes real-time communication feel fast, reliable, and natural on any device.Your work has a direct impact on how many people use communication on Roblox every day. and it sits at the center of our mission to reimagine how people come together. You will lead the charge in architecting a robust, highly scalable voice client foundation designed to serve as a company-wide platform. Your work will ensure that any internal team at Roblox can easily onboard and integrate voice capabilities into their products. By building this solid technical core, you will enable the next generation of social interactions, moving from simple in-experience chat to sophisticated, persistent social presence across the entire ecosystem. Furthermore, you will empower our creator community by developing sophisticated, yet accessible APIs that allow them to build deeply immersive experiences tailored to their unique visions. You'll design these systems with safety b

ReactAWSGitAI
R
📍 District of Columbia, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $294K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. Senior Director, Policy Communications Roblox is looking for an experienced communicator to support a wide range of issues, including leading public affairs communications. You will report to the Chief Communications Officer. As a member of the Global Communications and Corporate Affairs team, you will guide the development and implementation of corporate positioning and crisis management on a global scale. You will devise specific communications materials and campaigns to inform and educate our community, opinion leaders, media about the benefits of Roblox products, our company culture/values and our approach to public policy issues of the day. You will follow the regulatory environment that impacts our industry and, as appropriate, work with the policy team to comment on or respond to legislation. You will participate in face-to-face meetings with commentators and other opinion formers, develop print and web-based material supporting these campaigns, and counter misinformation that might interfere with our business and ability to serve our community. This role will ideally be based in either our Washington DC or San Mateo, CA offices (hybrid Tu

ReactAWSGitAI
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $221.4K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. WHY DATA SCIENCE & ANALYTICS? The Data Science & Analytics organization's mission is to increase our speed, frequency and acumen of making decisions at scale by instilling a data-influenced approach to building products. We cover a wide area of the data spectrum including analytical data engineering, product analytics, experimentation, causal inference, statistical modeling and machine learning. Aligned and partnering with product verticals, we use this extensive tool belt to discover new opportunities and unmet use cases, influence and shape the product roadmap and prioritization, build data products and measure impact on our community of players and developers. WHY AUTHENTICATION & SECURITY? Authentication & Security sits at the intersection of trust, product, and growth. The team builds the systems that allow users to sign in, recover, and protect their accounts with confidence, while defending the platform against account takeovers, credential abuse, and fraud at massive scale. This role is an opportunity to shape a high-stakes product area where small changes in friction or protection can meaningfully affect sign-ups and user frequency. You will act as a strategic leade

PythonSQLAWSGit
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $295.3K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. As a Principal Software Engineer on the Sharing team, you will lead large, multi-team initiatives with long-term technical vision and group-level impact. You will be expected to define and drive the platform-wide strategy powering how millions of users capture, share, and discover content on Roblox. In this role, you will set engineering standards, mentor senior engineers, and serve as a key architect of our long-term technical direction. You Will Drive Strategy & Execution: Own the outcome of complex, business-critical programs spanning several teams, often lasting years. Innovate at Scale: Develop and drive a multi-year technical vision for content creation and sharing, anticipating scale, technology, and business evolution. Elevate Reliability: Lead high-severity incident response across groups; drive durable systemic solutions that improve reliability and velocity. Architect Foundations: Regularly improve shared infrastructure and foundational systems, introducing frameworks that uplift development speed across the organization. Align Teams: Aligns multiple teams on shared technical direction, producing detailed design docs, phased roadmaps, and planning models that balance short an

JavaAWSGitAI
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $237.9K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. As Product Counsel / Sr Product Counsel for the Ads and Brands team, you will act as a key advisor and first point of legal contact to support our product, engineering, and other teams in building the future of the Roblox platform. Our mission as Product Counsel is to become product experts and to provide thoughtful and effective legal advice to help our business teams succeed. To accomplish this, we work closely with other members of the legal team and collaborate with a wide range of cross-functional teams to identify risks while maintaining a keen sense of business judgment. This role is dedicated to providing strategic legal advice to internal product and engineering teams, primarily in connection with our Ads and Brands team. The role requires application of complex, evolving legal frameworks to new and innovative products and services. This is a great opportunity to join a growing legal team, learn about interesting new technologies and business models, and work on novel issues in an exciting, fast-paced environment. You will: Act as a trusted advisor to Roblox product, engineering, and operations teams as well as company leadership throughout the product and process development

AWSGitRestAI
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $345K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. We are seeking a visionary Principal Software Engineer to join our Compute organization and provide technical leadership for our Kubernetes infrastructure. You will drive the evolution of a platform that powers our global scale operations, transforming Kubernetes into a secure, reliable, and invisible foundation for our developers across our on-prem and public cloud fleet. Your mission is to balance cutting-edge innovation with rigorous platform stability, ensuring that internal and external customers have a seamless, high-performance experience at massive scale. You Will: Architectural Leadership: Serve as a technical lead for our Kubernetes ecosystem, setting the long-term architectural strategy for a platform that manages thousands of nodes and supports millions of concurrent requests. Customer Focus: Think deeply about how our internal customers consume and interact with compute, designing intuitive interfaces and tooling that simplify consumption of complex infrastructure services. Deep-Dive Engineering: Leverage deep expertise in Kubernetes internals, including custom controllers, operators, API server architecture, and etcd, to solve complex scaling bottlenecks and optimize our contr

AWSKubernetesGitMicroservices
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $345K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. From the early days, simulated physics has been the foundation of the way users build in Roblox. Our physics engine enables dynamic environments with emergent behavior making games more immersive and exciting. The Physics team develops Roblox's proprietary distributed physics engine. Our team implements the mathematical models behind our dynamic simulation engine, and ships engine APIs and tools that developers use every day. These models incorporate rigid body dynamics arising from external forces, collisions, and constraints while optimizing for real-time performance. We work on integrating the low level physics solver into the rest of the engine for online gameplay across multiple platforms. You will report to the Physics Environment Engineering Manager. You Will: Innovate and implement powerful physics features that empower Roblox developers to create immersive and dynamic experiences. Drive innovation through research and rapid prototyping , translating new ideas into practical solutions that stand the test of time. Optimize and enhance the robustness and performance of the physics engine and its integrations, ensuring a seamless user experience. Collaborate with internal teams and ext

AWSGitRestAI
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $399.4K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. The platforms in our Engineering Acceleration org dictate how thousands of Roblox engineers ship, and how every backend service gets built, deployed, and kept reliable at scale. They sit on the critical path for production reliability, developer velocity, and security posture. Reporting to Andrew Swerdlow, you will rethink the entire engineering toolchain from the ground up to be agentic-native, creating a world where AI agents are first-class participants in software development and humans set direction and supervise. This is a unique opportunity to define what modern engineering infrastructure looks like at one of the largest platforms in the world. You will: Reimagine the engineering toolchain as agentic-native, designing the platforms, guardrails, and feedback loops that let AI agents safely drive migrations, validation, and routine operational work. Set a bold technical direction for AI-driven quality, including agent-generated tests, automated coverage of untested paths, intelligent verification, and continuous-deployment workflows. Make software quality and SEV prevention a measurable property of the platform by investing in safe-change mechanisms, automated verification, progressive

AWSKubernetesCI/CDGit
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