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Lead Enterprise Systems Engineer in San Francisco

609 active opportunities · Updated October 2026

Explore current lead enterprise systems engineer jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -73.5%

We believe that the way people interact with their finances will drastically improve in the next few years. We’re dedicated to empowering this transformation by building the tools and experiences that thousands of developers use to create their own products. Plaid powers the tools millions of people rely on to live a healthier financial life. We work with thousands of companies like Venmo, SoFi, several of the Fortune 500, and many of the largest banks to make it easy for people to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Washington D.C., London and Amsterdam. The Enterprise Partnerships team at Plaid works with some of the most influential enterprise companies, helping bring Plaid’s solutions to market through high-impact partnerships. In this role, you’ll lead the acquisition of new partners and play a meaningful role in expanding a fast-growing, strategically important part of the business. In this role, you'll be the primary point of contact for Enterprise partners with a specific focus on managing our payment partners looking to leverage Plaid in a number of ways from Pay-by-Bank to account funding to KYC. You own the full partner lifecycle: from technical integration and "first customer live" milestones to scaling volumes and driving product expansion. You are a "corporate athlete" who thrives in ambiguity: you are just as comfortable diving into technical API specifications with an engineer as you are negotiating commercial terms with a C-suite executive. You will act as the internal quarterback, driving cross-functional work streams across Product, Legal, Engineering, and Marketing to align internal resources with partner needs. Successful candidates bring a blend of commercial prowess, high-level business acumen, and a proven track record of infl

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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the team OpenAI’s mission is to build safe artificial general intelligence (AGI) which benefits all of humanity. This long-term undertaking brings the world’s best scientists, engineers, and business professionals into one lab together to accomplish this. In pursuit of this mission, our Go To Market (GTM) team is responsible for helping customers learn how to leverage and deploy our highly capable AI products across their business. The team is made of Sales, Solutions, Support, Marketing, and Partnership professionals that work together to create valuable solutions that will help bring AI to as many users as possible. About the role Our Sales team has a unique mission to help customers understand the deep impact that highly capable AI models can bring to their business and users. This role is a mixture of technical understanding, vision, partnership, and value-driven strategy. You’ll be a key driver of opportunities through the entire sales cycle, from pipeline generation to closure. You’ll work with researchers, engineers, and solution strategists to help customers evolve their industry with AI. This role is based in San Francisco. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you'll: Manage a portfolio of accounts, developing and executing strategies for a comprehensive account plan Lead our prospects’ journeys from consideration to successful deployment Partner with solutions and research engineering to build and execute complex customer programs and projects Own a consumption revenue target Manage consumption revenue forecasts Analyze key account metrics to create reports and provide insights to internal and external stakeholders Closely monitor the industry landscape (people, competitors, partners, etc.) to contribute to product roadmap and other corporate strategies Collaborate with solutions, marketing, communications, business operations, people operations, finance, product m

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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, United States· Full-time· Remote
✓ High-confidence listingCompany trend -86.4%
Quick readStrong listing-quality and freshness signals

About Pinterest: Millions of people around the world come to our platform to find creative ideas, dream about new possibilities and plan for memories that will last a lifetime. At Pinterest, we’re on a mission to bring everyone the inspiration to create a life they love, and that starts with the people behind the product. Discover a career where you ignite innovation for millions, transform passion into growth opportunities, celebrate each other’s unique experiences and embrace the flexibility to do your best work. Creating a career you love? It’s Possible. At Pinterest, AI isn't just a feature, it's a powerful partner that augments our creativity and amplifies our impact, and we’re looking for candidates who are excited to be a part of that. To get a complete picture of your experience and abilities, we’ll explore your foundational skills and how you collaborate with AI. Through our interview process, what matters most is that you can always explain your approach, showing us not just what you know, but how you think. You can read more about our AI interview philosophy and how we use AI in our recruiting process here . Pinterest is building the next phase of retail growth at the intersection of inspiration and commerce. As Director, Retail Transformation, you will lead a small team responsible for the operating model, strategy and end-to-end execution behind Pinterest’s most strategic retail partnerships across Retail Media, Future of Retail programs and tentpole moments. You will work across Sales, Product, Engineering, Data Science, Marketing and Content to develop clear strategic points of view across key retail growth areas, and to lead complex, multi-year initiatives from concept through delivery. You’ll translate partnership opportunities into scalable programs, new capabilities and measurable business outcomes. What you’ll do: Build and lead the centralized operating model for Pinterest’s most strategic retail partnerships, including prioritizati

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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -87.7%

$140K – $175K/yr

Quick readStrong listing-quality and freshness signals

About Flexport: At Flexport, we believe global trade can move the human race forward. That’s why it’s our mission to make global commerce so easy there will be more of it. We’re shaping the future of a $10T industry with solutions powered by innovative technology and exceptional people. Today, companies of all sizes—from emerging brands to Fortune 500s—use Flexport technology to move more than $19B of merchandise across 112 countries a year. The recent global supply chain crisis has put Flexport center stage as we continue to play a pivotal role in how goods move around the world. We are proud to have the support of the best investors in the game who believe in our mission, solutions and people. Ready to tackle global challenges that impact business, society, and the environment? Come join us. Equip businesses with the tools and insights to transform their supply chains This role has a robust compensation package: Base salary: $140,000-175,000; OTE: $280,000-350,000, uncapped accelerators, equity grants, competitive benefits and more. The opportunity: We’re looking for a pragmatic, growth-minded Sales Leader with a proven history of driving success to guide our San Francisco Sales Team. In this role, you’ll coach and develop Account Executive, building high-performing, inclusive teams to achieve company goals for volume growth and net revenue. You’ll play a critical part in developing talent for progression and promotion within our fast-growing organization. Reporting directly to our Regional General Manager, you’ll collaborate closely with our Executive Team to deliver key outcomes. This role features a 50/50 compensation model (Base + Uncapped bonus), designed for strong leaders to effectively maximize their earnings through a heavily incentivized sales program. You will: Build, inspire, and lead strong sales teams that consistently meet and exceed targets. Provide inclusive leadership and clear direction to a high-performance team, includi

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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -84.1%
Quick readStrong listing-quality and freshness signals

About the Team: We are a small and fast-moving partnerships team that shapes and executes OpenAI’s most important collaborations. Your mission is to identify, structure, and scale partnerships that expand how businesses adopt and benefit from OpenAI. You will work across priority sectors, including legal, professional services, information services, and other B2B categories, while maintaining the flexibility to pursue the highest-impact opportunities as the market evolves. About the Role: You are a senior business development and partnerships leader with strong judgment, high ownership, and a track record of originating and closing complex partnerships. You can move from market strategy and executive engagement through deal development, launch, and growth. You combine strategic thinking, commercial discipline, and hands-on execution, and you can create clarity and momentum across multiple internal and external stakeholders. Key Responsibilities: Develop a portfolio strategy for high-impact B2B partnerships. Identify and prioritize partners based on customer reach, differentiated data or workflows, distribution, strategic value, and growth potential. Originate, structure, negotiate, and launch complex product and commercial partnerships. Build joint value propositions and business plans spanning integration, distribution, go-to-market, and customer adoption. Lead executive relationships and establish durable cross-functional partnership governance. Coordinate product, engineering, sales, marketing, legal, finance, security, policy, and operations to deliver partnership outcomes. Translate partner and market insight into product strategy and new partnership models. Track adoption, pipeline, revenue impact, strategic milestones, and partner performance, and communicate progress and risks clearly. Qualifications: 10+ years of experience in strategic partnerships, business development, enterprise technology, or platform ecosystems. Proven experience personally originatin

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the Team OpenAI’s GTM Partnerships team builds a strategic, global partner ecosystem to accelerate customer success, enable responsible enterprise AI adoption, and drive durable growth in support of OpenAI’s mission. We work cross-functionally across Sales, Solutions, Product, Engineering, Security, Legal, Finance, Marketing, Operations, and Customer Success to translate strategic partnerships into measurable outcomes for customers. Global consulting and advisory partners are essential to helping enterprises move from AI strategy to production deployment. PwC brings global reach, deep industry and functional expertise, technology and transformation capabilities, and longstanding relationships with complex and regulated enterprises. This role will lead OpenAI’s global partnership with PwC and create the strategy, operating model, and field motions needed to turn that relationship into repeatable customer and commercial impact. This role is based in San Francisco, New York City, or Seattle. We use a hybrid work model of three days in the office per week. About the Role We are hiring a Partner Director, PwC to serve as the single accountable owner of OpenAI’s strategic relationship with PwC globally. You will define the partnership thesis and joint business plan, build executive alignment, activate PwC’s industry, advisory, technology, sales, and delivery organizations, and develop repeatable go-to-market motions that accelerate enterprise AI adoption. This is a strategic and hands-on leadership role. You will move fluidly between senior executive engagement, joint account and opportunity strategy, solution and delivery alignment, field enablement, governance, and day-to-day execution. Success requires a strong understanding of how a large, matrixed professional-services organization operates, commercial discipline, technical fluency, and the ability to align teams without relying on formal authority. The ideal candidate has led a high-impact global alliance with

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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, California, United States· Full-time· Remote
✓ Quality checkedCompany trend -84.1%

About the Role OpenAI’s Applications organization spans rapidly growing Consumer, Enterprise, Developer, and Hardware businesses. As we scale across EMEA, APAC, and LATAM, we’re building the financial and operating model that will help our regional teams make faster, better decisions. We are hiring a senior Strategic Finance partner to help shape that work. You’ll serve as a trusted advisor to regional GMs, connecting market strategy with business performance and guiding where and how we invest. By bringing together insights across growth, revenue, OpEx, headcount, and marketing effectiveness, you’ll help leaders understand market health, set priorities, and drive measurable outcomes. You’ll create the frameworks, operating rhythms, and decision processes needed to scale our international business, while contributing to broader Strategic Finance priorities across Marketing. This role is based in our San Francisco HQ. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. Periodic international travel is expected. In this role, you will: Own an integrated view of OpenAI’s international performance—spanning countries, regions, and Consumer, Enterprise/API, and Developer businesses—to guide growth, resource allocation, and investment decisions. Partner with regional GMs and functional leaders to shape country strategies spanning Product, Sales, Growth and Brand Marketing, Partnerships, Communications, and Policy. Lead regional financial planning and forecasting, tracking budgets, headcount, capacity, investments, and risks against the company plan. Build and operationalize investment frameworks across markets, channels, and programs, evaluating expected returns, opportunity costs, and tradeoffs to recommend what to fund and when. Create regional and country scorecards and lead regular business reviews that track key metrics, surface risks, drive decisions, and ensure follow-through. Design decision rights and escal

SQLAWSRestAI
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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the team OpenAI’s mission is to build safe artificial general intelligence (AGI) that benefits all of humanity. Achieving this requires bringing together world-class scientists, engineers, and business leaders to translate frontier research into real-world impact. Within OpenAI, the Go-to-Market organization helps customers understand, adopt, and scale our products across their businesses. The team includes Sales, Solutions, Support, Marketing, Partnerships, and Strategic Pursuits professionals who work together to bring the benefits of AI to organizations globally. About the role We are hiring a Senior Specialist Seller to join the Strategic Pursuits team and lead priority opportunities generated through the joint AWS and OpenAI co-sell motion. You will partner closely with Account Directors, AWS field teams, and cross-functional stakeholders to identify, shape, advance, and close high-value strategic enterprise engagements. This role is ideal for a senior seller with deep experience in enterprise technology, AI, cloud, or complex transformation sales motions. You should be comfortable operating in executive-facing environments, aligning multiple stakeholders, and turning customer priorities into commercially compelling and technically credible opportunities. This role is based in San Francisco, Seattle, or New York. We operate on a hybrid model of 3 days per week in office and offer relocation support. We are also open to remote candidates based in the United States. In this role, you will: Lead commercial execution of priority AWS/OpenAI co-sell opportunities across strategic enterprise accounts. Identify and qualify high-potential opportunities focused on GenAI adoption, frontier platform use cases, and enterprise-wide transformation. Partner with AWS and OpenAI field teams to align account strategy, messaging, stakeholder mapping, and execution plans. Develop customer-facing value propositions that connect OpenAI capabilities with business priorities and

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the Role The AI Deployment Manager (ADM) - Pilots is a customer-facing role responsible for leading structured, time-bound enterprise AI pilots from initial scoping through final executive readout. This role is focused on helping customers evaluate OpenAI’s products in real-world contexts, identify high-value use cases, and generate clear, decision-ready signals tied to business value. You will design and lead pilot engagements that drive activation, sustained usage, and measurable impact across ChatGPT Enterprise, Codex, and adjacent workflows. This includes partnering with customer stakeholders to define success criteria, guiding users from experimentation to real adoption, and translating pilot outcomes into clear recommendations that support expansion or purchase decisions. This role requires strong judgment, the ability to operate in ambiguity, and a consistent focus on connecting technical capabilities to business outcomes. You will regularly engage both executive stakeholders and working teams, adapting your approach to meet customers where they are and move them forward. In this role, you will: Own the design and execution of enterprise AI pilots, including scoping, cohort definition, and success criteria aligned to a clear commercial decision. Identify and prioritize a small set of high-impact use cases that can generate credible signal within a 30–45 day pilot. Drive activation and sustained engagement across pilot cohorts through targeted enablement, office hours, and workflow-level coaching. Monitor pilot performance and adapt in real time, diagnosing gaps in engagement, use case traction, or stakeholder alignment. Translate pilot signals into clear, executive-ready recommendations, including whether and how the customer should expand. Navigate customer constraints such as security, data access, and competing tools while maintaining pilot momentum. Partner closely with ADs, SEs, and customer stakeholders to align on scope, risks, and next steps. Ca

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the Team OpenAI’s GTM Partnerships team builds a strategic, global partner ecosystem designed to accelerate customer success, enable enterprise AI adoption, and drive durable growth in support of OpenAI’s mission. We work closely across Product, Research, Sales, Legal, Communications, and regional leadership to ensure a cohesive strategy and disciplined execution with our most strategic partners. About the Role We are hiring a Partner Director, Global McKinsey Alliance to lead and scale OpenAI’s relationship with McKinsey & Company. This role will serve as the single accountable executive owner of the alliance globally. You will define the partnership strategy and operating model, translating executive alignment into scaled commercial and transformation outcomes across regions and industries. You will work closely with McKinsey’s global leadership, industry and functional practices, and technology organizations—including QuantumBlack, AI by McKinsey—to develop differentiated enterprise AI offerings, pursue complex transformation opportunities, and help customers move from strategy to production deployment and measurable value. The role carries responsibility for the health, performance, and long-term expansion of the partnership. Success requires senior executive presence, sound judgment, commercial discipline, technical fluency, and the ability to operate effectively across a complex, partner-led organization. In this role, you will: Own the global McKinsey relationship, including alliance strategy, pipeline growth, enterprise impact, deployment scale, and long-term expansion across priority industries. Define and run the partnership’s operating model across executive governance, joint planning, regional execution, opportunity management, resource allocation, and escalation. Serve as OpenAI’s senior executive counterpart to McKinsey’s global leadership and relevant industry, functional, technology, and regional leaders. Develop a differentiated alliance s

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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the Team : We build core first-party app experiences in ChatGPT and Codex, define the primitives for high-quality app third-party app experiences, and collaborate with best-in-class partners across consumer and enterprise categories to bring delightful experiences to our customers. About the Role: We are hiring a Product Manager to shape and scale the app ecosystem across ChatGPT and Codex. This person will own both 1P product experiences and partner-led launches, translating user needs, model capabilities, platform constraints, developer and partner requirements, and enterprise controls into products that feel delightful, reliable, and safe. This position is based in San Francisco, CA, with relocation assistance available. In this role, you will: Develop the strategy and roadmap for ChatGPT and Codex app ecosystem experiences across consumer and enterprise use cases. Build and ship high-quality first-party app experiences that demonstrate the best of what apps can do inside ChatGPT and Codex. Collaborate with best-in-class partners to create app experiences that solve real user and business workflows. Define the product foundations and quality standards needed for a trusted app ecosystem. Lead cross-functional execution across engineering, design, research, partnerships, GTM, legal, privacy, security, support, and data/evals. Use customer, user, partner, and model-behavior insights to prioritize the roadmap and improve post-launch performance. You might thrive in this role if you: Have built and scaled consumer or enterprise product experiences with strong product taste and measurable user impact. Have built app platforms, marketplaces, partner ecosystems. Are technically fluent enough to reason about MCPs, APIs, SDKs, and model/product constraints. Can move fluidly between strategy, product, partner judgment, and operational execution. Communicate crisply in writing and bring clarity to ambiguous, fast-moving product areas. Care deeply about user trust, safe

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -92.7%

At Vanta, our mission is to help businesses earn and prove trust. We believe that security should be monitored and verified continuously, and we empower companies to practice better security and prove it with ease. Vanta has a kind and talented team, and while some have prior security experience, many have been successful at Vanta without it. Our GTM team is currently looking for a Manager, Sales Development to join us! As our Manager, Sales Development, you’ll lead and support a team of highly motivated and ambitious Sales Development Representatives during a period of rapid-growth at Vanta. These SDRs will be focused on the VMB, SMB and Enterprise segments of our NAMER business. You’ll be integral in shaping our sales organization as we continue to scale, move up market, and distinguish Vanta as best-in-class to prospects in our rapidly growing category of security automation, with Vanta having created the category of automated compliance. This role is hybrid in our San Francisco or New York City office 3 days per week. What you’ll do as a Manager, Sales Development at Vanta: Manage and mentor a growing team of high performing Sales Development Representatives, providing them the tools, coaching, and support needed to deliver results for the business Evolve Vanta’s prospecting playbook by developing and implementing new prospecting initiatives and strategies that will increase deal sizes, resolve complex use cases, and drive more revenue to the company Grow the Sales Development team at Vanta, through active involvement in recruitment, on-boarding and training of new Sales Development Representatives Create and establish strategic prospecting training, conduct weekly forecasting meetings, and mentor your direct reports on strategies that can help create pipeline Help to continually foster an inclusive Sales organization representing Vanta’s culture and values Ensure development plans are in place, adapted to each individual, and made useful in a way that ensures t

RestAgileAIGo
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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the Team The AI Deployment Management (ADM) team enables organizations to turn OpenAI products into real, sustained impact through world-class services execution. Our mission is to help customers successfully adopt and operationalize AI across their organizations. We partner with enterprises to translate the potential of OpenAI’s technology into durable capability - through structured training, technical enablement, and services. By helping customers move from experimentation to production, the ADM team accelerates time-to-value, deepens product adoption, and helps make OpenAI indispensable to how organizations work. About the Role The AI Deployment Manager role is a specialist post-sales enablement role focused on delivering high-impact enablement and adoption services across OpenAI’s product suite. This role is responsible for designing and delivering enablement experiences that support a repeatable adoption framework, driving sustained activation, expanding breadth and depth of usage, and measurable business value across OpenAI’s product suite, including ChatGPT Enterprise and Agents. This role blends strong product fluency, instructional design, and customer advisory. You will lead live workshops, deliver services, and design adoption interventions for audiences ranging from everyday business users to technical practitioners and executive leaders, helping customers understand not just what OpenAI’s products can do, but how to apply them effectively in real world workflows. Success in this role means accelerating customer confidence, increasing product adoption, supporting successful launches of new product capabilities, and helping customers translate product features into tangible outcomes across teams and business functions. You will own outcomes related to activation and sustained usage by shaping how enablement drives measurable customer impact. This role is based in our San Francisco office. We use a hybrid work model of 3 days in the office per week

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the Team OpenAI’s AI Success Engineer team partners with the world’s most ambitious organizations to translate cutting edge AI into real business value. We guide customers from first deployment through scaled enterprise adoption. Our work spans technical integration and enablement, workflow transformation, and sustained program and product delivery. Our customers range from fast growing digital natives to the largest global enterprises, government agencies and educational institutions. Every engagement is an opportunity to shape how AI changes work, productivity, and innovation. This role sits at the center of that mission. About the Role The Success Engineer role is the primary post-sales point of contact for a portfolio of education institutions. You are responsible for driving account health and adoption, ensuring technical readiness, identifying high-impact academic and administrative use cases, and delivering measurable value to our education customers using OpenAI’s platform. This role blends technical leadership, program management, customer advisory, and product influence. You will partner deeply with customer teams, map workflows, lead configuration and enablement, oversee deployment plans, and guide institutions toward high impact use cases that showcase the full value of our platform. You will work closely with Sales, Solutions Architecture, Product, and Research to ensure the customer experience is connected and successful across every touchpoint. Success in this role means accelerating adoption, increasing customer activation depth, guiding strategic use cases that get to production, and helping customers demonstrate tangible business impact. This role is based in SF or NYC; we offer relocation benefits to new hires. In this role, you will: Lead the technical relationship for post-sale customers and act as their trusted advisor on deployment, adoption, and value realization Own account health, adoption velocity, and ongoing technical deployment an

AWSGitRestAI
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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -7.5%
Quick readStrong listing-quality and freshness signals

🚀 About WRITER WRITER is where the world's leading enterprises orchestrate AI-powered work. Our vision is to expand human capacity through superintelligence. And we're proving it's possible – through powerful, trustworthy AI that unites IT and business teams together to unlock enterprise-wide transformation. With WRITER's end-to-end platform, hundreds of companies like Mars, Marriott, Uber, and Vanguard are building and deploying AI agents that are grounded in their company's data and fueled by WRITER's enterprise-grade LLMs. Valued at $1.9B and backed by industry-leading investors including Premji Invest, Radical Ventures, and ICONIQ Growth, WRITER is rapidly cementing its position as the leader in enterprise generative AI. Founded in 2020 with office hubs in San Francisco, New York City, Austin, Chicago, and London, our team thinks big and moves fast, and we're looking for smart, hardworking builders and scalers to join us on our journey to create a better future of work with AI. 📐 About the role At WRITER, we're not just building the future of enterprise AI; we're actively orchestrating it. The director, solutions architecture plays a pivotal role in this journey, leading a team of exceptional solutions architects who empower our enterprise customers to unlock the full potential of our cutting-edge generative AI platform. You’ll be at the forefront of driving AI transformation, moving beyond theoretical discussions to hands-on deployment and measurable impact. This is your chance to lead, mentor, and inspire a team dedicated to solving complex business challenges with innovative AI solutions, directly influencing customer success and WRITER's rapid growth. This is a full-time, hybrid role based out of our San Francisco hub. You will report directly to the VP of solutions architecture. 🦸🏻‍♀️ What you'll do Lead and empower a team of highly skilled solutions architects, fostering their technical growth and career development across complex enterprise AI engagem

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