Jobs in United States

Lead Staff Technical Program Manager in United States

2,434 active opportunities · Updated October 2026

Explore current lead staff technical program manager jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

Hiring demand

43/100

watch · 145 related jobs

Hiring trend

-65.7%

Job postings compared with the previous 30 days

Remote options

20.7%

Share of matching jobs listed as remote

Typical salary

$145.7K – $145.7K/yr

Based on 9 salary observations

P
📍 New York, United States
✓ High-confidence listingCompany trend +671.4%

$300.1K – $500.1K/yr

Quick readStrong listing-quality and freshness signals

Role Summary This role serves as the single point of accountability between USMAPPS and the Oncology Business Unit, owning access strategy, payer marketing, and brand-level contracting and pricing strategy across the full oncology portfolio. The role drives and owns outcomes, integrating all USMAPPS capabilities into one coherent access plan that directly supports the Oncology BU President and franchise leads. The Vice President is expected to operate at full strategic weight, lead a team aligned to oncology brands and franchise clusters, and be the single person the Oncology BU holds accountable for market access results. The Vice President, US Market Access Lead – Oncology reports directly to the Senior Vice President of US Market Access & Pfizer Patient Services (USMAPPS) with a dotted line to the Oncology BU President . This position requires close partnership with the Oncology BU President, franchise leads, Strategic Contracting & Analytic s , Strategic Account Management, the Patient Services, and USMAPPS leadership. The role sits on the Oncology BU leadership team and on the USMAPPS Leadership Team. Role Responsibilities 1. Oncology Access Strategy Ownership Develop and maintain a fully integrated brand market access plan for all oncology brands, covering payer marketing, contracting strategy, and pricing strategy in one coherent plan </

AIRecruitment
B
📍 Berkeley, United States
✓ Quality checkedCompany trend +515.8%

Cloud Platform Administrator (Mid-Level, Senior or Lead) **Sign on Bonus Potential** Company: The Boeing Company The Boeing Company’s Specialized United States Infrastructure Operations is currently seeking a Cloud Platform Administrator (Mid-Level, Senior or Lead) to join the team in Berkeley, MO; Seattle, WA; or Daytona Beach, FL . The Infrastructure team is seeking a skilled platform engineer to help build and operate the cloud platform services that host critical enterprise applications and software toolchains. In this role, the selected candidate will focus on the shared platform capabilities that enable teams to deploy, run, and maintain containerized and cloud-hosted solutions in a consistent and supportable manner. As both an individual contributor and technical leader, this position will help define and implement platform standards for Kubernetes, container hosting, deployment automation, configuration management, and operational support. This role is focused on platform reliability, repeatability, scalability, and service enablement, rather than custom application software development. Position Responsibilities: Design, implement, and maintain cloud platform services supporting Kubernetes, containers, ingress, storage integration, secrets management, and service connectivity Build and sustain reusable deployment patterns for Commercial-Off-The-Shelf (COTS), Open Source Software (OSS), and internally customized applications Develop and maintain automation for platform provisioning, upgrades, patching, and lifecycle support Manage cluster lifecycle activities including: Cluster upgrades Node management <

AWSAzureDockerKubernetes
B
📍 Berkeley, United States
✓ Quality checkedCompany trend +515.8%

Cloud Infrastructure Administrator (Mid-Level, Senior or Lead) **Sign on Bonus Potential** Company: The Boeing Company The Boeing Company’s Specialized United States Infrastructure Operations organization is currently seeking a Cloud Infrastructure Administrator (Mid-Level, Senior or Lead) to join the team in Berkeley, MO; Seattle, WA; or Daytona Beach, FL . The Infrastructure team is seeking an experienced cloud infrastructure professional to help design, build, and sustain the foundational cloud environment supporting critical program needs. In this role, the selected candidate will help establish and operate secure, scalable, and resilient cloud infrastructure environments in Microsoft Azure to enable enterprise applications, software toolchains, and digital engineering workloads. As both an individual contributor and technical leader, this position will work across network, computer, storage, identity, security, and automation domains to deliver repeatable cloud infrastructure patterns and operational excellence. This role is focused on infrastructure operations, sustainment, automation, and reliability, rather than application software development. Position Responsibilities: Design, implement, and maintain Microsoft Azure-based infrastructure solutions including networking, compute, storage, identity integration, and supporting services Develop and maintain Infrastructure as Code (IaC) and configuration automation solutions using Terraform, Ansible, PowerShell, and Bash Implement cloud policies to enforce security, ensure regulatory compliance, and manage user access Build repeatable landing zones and cloud infrastructure patterns that support mul

AzureTerraformAnsibleSap
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -82%

About the Team OpenAI’s mission is to ensure that artificial general intelligence benefits all of humanity. Customer Education plays an important role in that mission by helping people and organizations use increasingly capable AI systems effectively, responsibly, and with confidence. We create learning experiences, programs, and resources that help customers move from initial understanding to sustained use and measurable impact. As our products, audiences, and programs grow, we need an operating foundation that keeps the content portfolio trusted, clarifies complex work, and helps the team deliver at a consistently high standard. This role offers the opportunity to build the operational foundation behind education programs that shape how enterprises adopt frontier AI. About the Role We are looking for a strategic operator to own the operating system behind Customer Education. You will work at the center of content, systems, and team execution: owning the health of our education content portfolio, running the team’s operating rhythm, and translating evolving business needs into scalable workflows and system requirements. The right person will raise the quality of execution across Customer Education. You will bring order, judgment, and follow-through to a fast-moving environment, making the function easier to run, easier to trust, and easier to scale. In this role, you will: Own the health and integrity of the Customer Education content portfolio, including lifecycle, governance, discoverability, reuse, and meaningful gaps. Ensure customer-facing teams can confidently find and use the right education resources at the right time. Run the team’s operating rhythm across priorities, ownership, timelines, dependencies, decisions, launch readiness, and follow-through. Turn ambiguous cross-functional initiatives into clear plans, workflows, responsibilities, and decision points. Design scalable processes and handoffs for how education programs are created, launched, maintai

AWSRestAIGo
N
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -87.4%

From $299K/yr

Quick readStrong listing-quality and freshness signals

Who We Are Notion is the collaborative AI workspace where teams and agents think together . We're building one place where your knowledge, projects, meetings, and AI tools live side by side, so work is faster, clearer, and less fragmented. Millions of individuals, small teams, and large companies run their work on Notion. Notinos (our employees) are customer zero in bringing this future of work to life. We care about craft, building things that last, and the belief that great work is still fundamentally human. Our goal isn’t to ship the next feature. Each and every team of Notinos is working to set the standard for how humans work together in the AI era. From building a business’s system of record to making and managing AI agents to automating away the busy work, we care deeply about giving our customers more time for their life’s work. About the Role We’re rolling out Go support at production scale at Notion, and we need an owner who can make it durable. You’ll lead the work to turn Go into a fully supported, well-operated platform: reliable and scalable service patterns, paved paths for our tooling stack, and the guardrails that make building in Go feel fast and safe. This role matters because our next wave of AI and agent-driven products will require backend services where Node won’t always be the right fit, and the platform decisions we make now will compound for years. While Go is the core focus, this role sits within Developer Experience and will regularly tackle other high-leverage engineering productivity challenges, developer experience ranging from AI-assisted development workflows and remote agent environments to CI performance, deployments, and reliability tooling. This role can be based in either San Francisco or New York City. We work from our offices on Mondays, Tuesdays and Thursdays (our Anchor Days) because we do our best thinking and building together in person. We’re looking for someone who’s excited to work alongside the team during those days.

TypeScriptKubernetesRestAI
S
📍 Menlo Park, California, United States· Full-time
✓ Quality checkedCompany trend -92.9%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. About the Team Strategic Finance is the commercial and analytical engine behind Snowflake's product and revenue decisions. The team operates at the intersection of product strategy, pricing, and investment prioritization. Strategic Engagements, the function this role sits within, owns Snowflake's most consequential customer pursuits, partnerships, and M&A engagements. We bring financial, product, market, and pricing depth to the deals that determine quarters, set commercial precedent, and shape Snowflake's largest customer relationships. About the Role We are hiring two Strategic Engagements Deal Leads to own the commercial structuring and execution of Snowflake's most consequential customer engagements across North America. You will own the deal-by-deal economic frame, commercial recommendation, and structuring approach for the company's highest-priority strategic engagements. The portfolio spans the full range of qualifying deals: net-new logo acquisitions, multi-year capacity expansions in installed-base accounts, partnership-driven commercial structures, and deals that set commercial precedent for new business models. You will partner directly with account leadership, Specialist Sales, AI Specialists, Deal Desk, Legal, Pricing, and Revenue Accounting. You will join

SQLAWSAIGo
B
📍 Oklahoma City, OK, United States
✓ High-confidence listingCompany trend +515.8%
Quick readStrong listing-quality and freshness signals

Wire Harness Installation Engineer (Associate, Experienced, or Lead) Company: The Boeing Company Boeing Defense, Space, & Security (BDS) is looking for a Wire Harness Installation Engineer (Associate, Experienced, or Lead) to join our team in Oklahoma City, OK . This position will provide engineering support across the Boeing portfolio of products, to include – but not limited to – Boeing Military Aircraft and Military Derivative Aircraft (AEW&C, AWACS, C-32/C-40, E-4B, VC-25A, KC-767, B-1B, B-2, B-52 and others). Our teams are currently hiring for a broad range of experience levels including Associate, Experienced, or Lead Level Engineers. Position Responsibilities Associate (Level 2) Develops and maintains wire harness installation engineering drawings Supports analysis and design reviews Develops and maintains electrical product detail, assembly and installation designs (e.g., equipment racks, power panels, cable routing and geometry, antennas) Provides engineering design disposition on discrepancies (e.g., rejection tags, production action requests, shop revision requests) Follows documented processes, specifications and procedures that support the design and manufacture of electrical commodities Supports the development of statements of work. Assists in the technical review of supplier capabilities to facilitate source selection Analyzes functional and physical input used in the development of integrated design and system architecture. Works under general supervision.</spa

Recruitment
B
📍 Oklahoma City, OK, United States
✓ High-confidence listingCompany trend +515.8%
Quick readStrong listing-quality and freshness signals

Hydraulic Systems Engineer (Associate, Experienced, or Lead) Company: The Boeing Company Boeing Defense, Space & Security (BDS) Mobility, Surveillance and Bombers (MS&B) B-52 Commercial Engine Replacement Program (CERP ) is seeking a Hydraulic Systems Engineer (Associate, Experienced or Senior) to join the Systems Engineering, Integration, and Test (SEIT) team . The selected candidate will drive engineering excellence on this complex development program in Oklahoma City, OK . Position Responsibilities: Operate as the team’s Subject Matter Expert on the B-52 Hydraulics Subsystem. Lead systems and multifunctional engineering efforts for the SEIT IPT, ensuring adherence to technical quality standards throughout the product lifecycle Collaborate with cross-functional teams, including design, manufacturing, and quality assurance, to define and implement systems engineering processes and best practices Conduct trade studies and risk assessments to inform design decisions and optimize system performance, cost, and schedule Develop and maintain system requirements, interface control documents, and verification and validation plans to ensure compliance with customer specifications and regulatory standards Oversee the integration of hardware and software components in System Integration Labs in Oklahoma City Oversee the verification and test of hardware and software components supporting the modification in San Antonio

Recruitment
P
📍 New York, United States
✓ High-confidence listingCompany trend +671.4%

$230.9K – $384.8K/yr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY Pfizer Commercial Oncology is introducing the world to the next era of cancer care. With a growing portfolio of novel therapies, industry-leading R&D, and a goal of delivering eight breakthroughs by 2030 across major cancer types, we're translating cutting-edge science into market-shaping impact. Here, you'll partner with exceptional colleagues across scientific, medical, and manufacturing teams, backed by advanced digital and AI-enabled infrastructure and the authority to accelerate medicines from discovery to delivery. Guided by our values of courage, excellence, equity, and joy, you'll have the opportunity to stretch your skills and build a career that evolves with you—across teams, roles, and the Pfizer enterprise. Join us to make history — for patients, for their families, for the future. The US Precision Medicine Thoracic Franchise is entering its most consequential — and most complex — growth chapter. Our in-line thoracic portfolio spans two biomarker-defined populations: LORBRENA (lorlatinib) for adults with ALK-positive metastatic non-small cell lung cancer (NSCLC), and the BRAFTOVI &#43; MEKTOVI (encorafenib &#43; binimetinib) regimen for BRAF V600E-mutant metastatic NSCLC. Both sit inside a molecularly driven treatment landscape where the right patient is identified by a biomarker signature. Winning here means mastering precision targeting: reaching narrow, high-value, genomically defined patient populations through the exact clinicians who test for and treat them. This is a people-management leadership role that demands a strong enterprise leader — one fluent in both commercial strategy and AI-enabled execution, and able to think and operate at the enterprise level. The colleague who leads this team will set a multi-year strategic vision, make thoughtful trade-off and resource-prioritization decisions across two brands, and influence senior leadership across the wider organizati

Machine LearningAIExcelRecruitment
G
📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$195.7K – $253.2K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description At Gilead our pursuit of a healthier world for all people has yielded a cure for hepatitis C, revolutionary improvements in HIV treatment and prevention as well as advancements in therapies for viral and inflammatory diseases and certain cancers. We set and achieve bold ambitions in our fight against the world’s most devastating diseases, united in our commitment to confronting the largest public health challenges of our day and improving the lives of patients for generations to come. The Protein Therapeutics Department is seeking a laboratory-based Automation Engineer to join the Protein Sciences team. This role will lead the design, implementation, integration and suppor

PythonJavaRecruitment
D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -85.2%
Quick readStrong listing-quality and freshness signals

Datadog's integrations are the connective tissue between our platform and the technologies our customers run in the real world. As a Sr. PM on the Agent Integrations team, you will own the vision, prioritization, and execution for 100+ integrations that run directly inside the Datadog Agent from foundational infrastructure (MySQL, Kafka, Kubernetes) to the rapidly growing landscape of self-hosted AI and on-premise enterprise technologies. This is a high-impact, breadth-first role at the intersection of infrastructure observability and the frontier of AI-native workloads. At Datadog, we place value in our office culture; the relationships it builds, the creativity it brings, and the collaboration of being together. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You'll Do: Own the Agent Integrations roadmap. Determine which new integrations to build and which existing ones to improve, balancing customer demand, business impact, and engineering capacity across a catalog of 100+ technologies. Drive the expanding AI integration surface. Lead product strategy for self-hosted AI workloads, including LLM inference frameworks (e.g., Hugging Face TGI, BentoML), AI agents, MCP servers, and model orchestration tools, so Datadog customers can monitor every layer of their AI stack. Expand on-prem and hybrid coverage. Prioritize and execute new integrations for on-prem technologies including storage systems, HPC schedulers, network devices, and legacy enterprise platforms where customers run critical workloads. Build observability for ERP systems. Define and drive Datadog's strategy for monitoring enterprise ERP platforms (SAP, Oracle EBS/Fusion, Microsoft Dynamics) covering performance, job execution health, and integration layer telemetry so enterprise customers can observe their ERP stack alongside the rest of their infrastructure. Analyze adoption and customer feedback at scale. Use data from multiple sources to

SQLPostgreSQLMySQLMongoDB
C
📍 Irving Texas United States, United States
✓ High-confidence listingCompany trend +800%
Quick readStrong listing-quality and freshness signals

The Applications Development Technology Lead Analyst is a senior level position responsible for building robust, high-performance, large-scale applications. The overall objective of this role is to lead applications systems analysis and programming activities. Responsibilities: * Partner with multiple management teams to ensure appropriate integration of functions to meet goals as well as identify and define necessary system enhancements to deploy new products and process improvements * Resolve variety of high impact problems/projects through in-depth evaluation of complex business processes, system processes, and industry standards * Provide expertise in area and advanced knowledge of applications programming and ensure application design adheres to the overall architecture blueprint * Utilize advanced knowledge of system flow and develop standards for coding, testing, debugging, and implementation * Develop comprehensive knowledge of how areas of business, such as architecture and infrastructure, integrate to accomplish business goals * Provide in-depth analysis with interpretive thinking to define issues and develop innovative solutions * Serve as advisor or coach to mid-level developers and analysts, allocating work as necessary * Appropriately assess risk when business decisions are made, demonstrating particular consideration for the firm's reputation and safeguarding Citigroup, its clients and assets, by driving compliance with applicable laws, rules and regulations, adhering to Policy, applying sound ethical judgment regarding personal behavior, conduct and business practices, and escalating, managing and reporting control issues with transparency. Qualifications: * 5 to 8 years of relevant experience in Apps Development or systems analysis role * Extensive experience system analysis and in programming of software applications * Hands-on experience in

JavaReactDockerKubernetes
C
📍 Irving Texas United States, United States
✓ High-confidence listingCompany trend +800%
Quick readStrong listing-quality and freshness signals

The Applications Development Technology Lead Analyst is a senior level position responsible for building robust, high-performance, large-scale applications. The overall objective of this role is to lead applications systems analysis and programming activities. Responsibilities: * Partner with multiple management teams to ensure appropriate integration of functions to meet goals as well as identify and define necessary system enhancements to deploy new products and process improvements * Resolve variety of high impact problems/projects through in-depth evaluation of complex business processes, system processes, and industry standards * Provide expertise in area and advanced knowledge of applications programming and ensure application design adheres to the overall architecture blueprint * Utilize advanced knowledge of system flow and develop standards for coding, testing, debugging, and implementation * Develop comprehensive knowledge of how areas of business, such as architecture and infrastructure, integrate to accomplish business goals * Provide in-depth analysis with interpretive thinking to define issues and develop innovative solutions * Serve as advisor or coach to mid-level developers and analysts, allocating work as necessary * Appropriately assess risk when business decisions are made, demonstrating particular consideration for the firm's reputation and safeguarding Citigroup, its clients and assets, by driving compliance with applicable laws, rules and regulations, adhering to Policy, applying sound ethical judgment regarding personal behavior, conduct and business practices, and escalating, managing and reporting control issues with transparency. Qualifications: * 6 to 9 years of relevant experience in Apps Development or systems analysis role * Extensive experience system analysis and in programming of software applications * Hands-on experience in

JavaReactDockerKubernetes
C
📍 Irving Texas United States, United States
✓ High-confidence listingCompany trend +800%
Quick readStrong listing-quality and freshness signals

The Applications Development Technology Lead Analyst is a senior level position responsible for building robust, high-performance, large-scale applications. The overall objective of this role is to lead applications systems analysis and programming activities. Responsibilities: * Partner with multiple management teams to ensure appropriate integration of functions to meet goals as well as identify and define necessary system enhancements to deploy new products and process improvements * Resolve variety of high impact problems/projects through in-depth evaluation of complex business processes, system processes, and industry standards * Provide expertise in area and advanced knowledge of applications programming and ensure application design adheres to the overall architecture blueprint * Utilize advanced knowledge of system flow and develop standards for coding, testing, debugging, and implementation * Develop comprehensive knowledge of how areas of business, such as architecture and infrastructure, integrate to accomplish business goals * Provide in-depth analysis with interpretive thinking to define issues and develop innovative solutions * Serve as advisor or coach to mid-level developers and analysts, allocating work as necessary * Appropriately assess risk when business decisions are made, demonstrating particular consideration for the firm's reputation and safeguarding Citigroup, its clients and assets, by driving compliance with applicable laws, rules and regulations, adhering to Policy, applying sound ethical judgment regarding personal behavior, conduct and business practices, and escalating, managing and reporting control issues with transparency. Qualifications: * 5-8 years of relevant experience in Apps Development or systems analysis role * Extensive experience system analysis and in programming of software applications * Hands-on experience in We

JavaReactDockerKubernetes
G
📍 Austin, Texas, United States· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

About the job Lead the team that proves our AI silicon performs reliably before it reaches customers. You will build and lead Graphcore's characterisation capability for next generation silicon and system platforms. Your work will help ensure our products perform consistently across real world conditions. You will define bring up and characterisation strategies, lead technical execution, and shape the lab infrastructure needed for success. You'll work across silicon, hardware, manufacturing, architecture and product teams to solve complex engineering challenges. This is a hands on leadership role with the opportunity to influence both product design and how Graphcore validates future AI systems. The team and culture This is a newly formed team within Manufacturing Operations. You'll have the opportunity to establish how the team works while building strong partnerships across engineering and operations. Day to day, you'll work closely with architecture, silicon, hardware, production test and product teams. Decisions are driven by data, technical evidence and close collaboration across disciplines. We value ownership and clear communication. You'll be trusted to lead technical direction, remove blockers and help teams make progress with confidence. What we're looking for Essential Proven track record of delivering complex technical projects as an individual contributor, manager, or project manager, with the ability to work independently and drive execution. Strong expertise in silicon digital device design, bring-up, characterisation, and silicon process technologies, with an understanding of their impact on transistor- and system-level performance. In-depth knowledge of high-performance processors, system-on-chip (SoC) architectures, and high-speed digital interfaces such as PCIe, Ethernet, and DDR. Experience with measurement automation, data analysis, and scripting/coding to develop automated test and analysis workflows, with familiarity of ATE systems and t

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