Jobs in United States

Senior Lead Technical Program Manager Knowledge Systems in United States

1,941 active opportunities · Updated October 2026

Explore current senior lead technical program manager knowledge systems jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

Hiring demand

43/100

watch · 145 related jobs

Hiring trend

-65.7%

Job postings compared with the previous 30 days

Remote options

20.7%

Share of matching jobs listed as remote

Typical salary

$145.7K – $145.7K/yr

Based on 9 salary observations

A
📍 United States· Full-time
✓ High-confidence listingCompany trend -98.8%

From $204K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: Hotels represent one of Airbnb's most exciting growth frontiers, bringing professional hospitality partners onto the platform and making it possible for guests to choose Airbnb for every kind of trip. By ensuring a robust and exceptional hotel supply, the Revenue Operations team plays a critical role in shaping Airbnb's future and delivering on its mission to create a world where anyone can belong anywhere. The Revenue Operations team partners across the company to build world-class Sales, Onboarding, and Account Management capabilities. We support partners across the full journey – from identifying and acquiring the right supply in the right markets, to seamless onboarding and integration, to the tools, programs, and insights that help partners grow and succeed on our platform. We own critical growth levers that ladder directly into business goals, and we build the central infrastructure that powers in-market execution for field teams worldwide. The Difference You Will Make: Acquiring the right hotels in the right markets is one of the most critical drivers of Hotels growth at Airbnb – and this role sits at the center of that effort. As Sr. Lead, Revenue Operations – Hotels Acquisition, you will own the global acquisition operations strategy, partnering with regional sales leaders, marketing, product, and central analytics teams to drive funnel performance, optimize conversion, and scale what works across markets. You will serve as the global subject matter expert on hotel acquisition levers — bringing strategic clarity to how and where we acquire supply, translat

N
📍 Santa Clara, United States
✓ High-confidence listingCompany trend -8%
Quick readStrong listing-quality and freshness signals

The Silicon Co-Design Group (SCG) sits at the crossroads of architecture, design, marketing, operations, and productization. Our work spans early architecture through final product delivery across Datacenter, Gaming, Robotics, Automotive, and Embedded markets. We work closely across functions to deliver chips that change what is possible. System Integration sits at the intersection of all of them. It is the layer where every architecture, design, software, and manufacturing decision meets reality. When something breaks late in a program, it usually breaks here first. We are hiring a Senior Manager to lead this team in the US and partner closely with teams globally. Your work will sit on the critical path of every NVIDIA silicon program, and the bar you set for system integration is the bar we ship to! The two hardest, highest-leverage problems in this seat: Find critical silicon issues earlier — often before software is production-ready. Left-shifting post-silicon coverage is the highest-value thing System Integration can do. Standing up wide-area testing as a repeatable capability is a core part of the role. Keep programs on milestone when upstream dependencies slip. Validation plans collide with reality every program! The team needs new strategies, not just contingency plans, to keep moving when software, firmware, or methodology slip. You will design and run those strategies. What you’ll be doing: Plan and execute post-silicon feature integration, PVT validation, and wide-area testing across NVIDIA’s GPU, SoC, and CPU programs. Build wide-area and in-system test as a repeatable capability that shifts post-silicon coverage left, so issues surface before we are production-ready. Lead resolution of the most complex system-level issues, RMAs, and HW/SW interaction problems with creative workarounds and focused lab experimentation. Deve

B
📍 Berkeley, United States
✓ High-confidence listingCompany trend +515.8%
Quick readStrong listing-quality and freshness signals

Senior Systems Engineering Manager (Systems Engineering Management) Company: The Boeing Company Boeing Defense, Space & Security (BDS) is looking for a Senior Systems Engineering Manager (Level M) to join the System Engineering, Integration and Test (SEIT) Team in Berkeley, MO . The SEIT Senior Manager will lead a high-performing, cross-functional Systems Engineering, Integration, and Test (SEIT) team, driving the development and delivery of cutting-edge capabilities for the Air Proprietary Program. This position reports directly to the Air Proprietary SEIT Director. This position will plan, organize and direct activities for the Air Proprietary Systems Engineering team. A successful candidate will have familiarity with: Model Based System Engineering (MBSE) using MSOSA tools System Engineering best practices, processes, and procedures Design, Integration, and Test including architecture, interfaces, requirements, modeling, and verification Certification including Airworthiness, Certifications, and SCFTA Configuration Management & Data Management including Teamcenter/IPDM, SSOWs, SDRLs Specialty Engineering including FMECA, R&M, Supportability, System Health, and Human Engineering EME/EEE & Product Security including EMC, TEMPEST, System Security, and Cyber Collaboration with System Safety Function including CSIs, Hazard analysis, and SSWGs Position Responsibilities Responsible for integration across the Air Proprietary program statement of work ensuring synchronized work is accomplished in support of the integrated master schedules and in compliance to customer requirements Oversees translating strategies int

SapRecruitment
B
📍 Salt Lake City, Utah, United States· Full-time
✓ High-confidence listing

$200K – $250K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Sales at Brex Sales is the growth engine at Brex. We bring in new customers, expand existing relationships, and drive the company’s bottom line. With unlimited territories and uncapped opportunity, your ambition sets the ceiling. We win together, celebrate often, and reward performance. If you want to sell a category-defining product with real ownership, this is your team. What you'll do We're seeking an experienced Senior Manager to lead our Sales Development organization. In this second-line leadership role, you will manage a team of SDR Managers, drive pipeline generation strategy, and build the scalable systems that turn early-career sales talent into high-performing revenue contributors. Where you'll work This role will be based in our Salt Lake City office. We are a hybrid environment that combines the energy and connections of being in the office with the benefits and flexibility of working from home. We currently require a min

AIGoExcelMarketing
B
📍 Seattle, Washington, United States· Full-time
✓ High-confidence listing

$226K – $282.5K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Sales at Brex Sales is the growth engine at Brex. We bring in new customers, expand existing relationships, and drive the company’s bottom line. With unlimited territories and uncapped opportunity, your ambition sets the ceiling. We win together, celebrate often, and reward performance. If you want to sell a category-defining product with real ownership, this is your team. What you'll do We're seeking an experienced Senior Manager to lead our Sales Development organization. In this second-line leadership role, you will manage a team of SDR Managers, drive pipeline generation strategy, and build the scalable systems that turn early-career sales talent into high-performing revenue contributors. Where you'll work This role will be based in our Seattle office. We are a hybrid environment that combines the energy and connections of being in the office with the benefits and flexibility of working from home. We currently require a minimum of

AIGoExcelMarketing
B
📍 New York, New York, United States· Full-time
✓ High-confidence listing

$226K – $282.5K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Sales at Brex Sales is the growth engine at Brex. We bring in new customers, expand existing relationships, and drive the company’s bottom line. With unlimited territories and uncapped opportunity, your ambition sets the ceiling. We win together, celebrate often, and reward performance. If you want to sell a category-defining product with real ownership, this is your team. What you'll do We're seeking an experienced Senior Manager to lead our Sales Development organization. In this second-line leadership role, you will manage a team of SDR Managers, drive pipeline generation strategy, and build the scalable systems that turn early-career sales talent into high-performing revenue contributors. Where you'll work This role will be based in our New York City office. We are a hybrid environment that combines the energy and connections of being in the office with the benefits and flexibility of working from home. We currently require a mini

AIGoExcelMarketing
B
📍 San Francisco, California, United States· Full-time
✓ High-confidence listing

$226K – $282.5K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Sales at Brex Sales is the growth engine at Brex. We bring in new customers, expand existing relationships, and drive the company’s bottom line. With unlimited territories and uncapped opportunity, your ambition sets the ceiling. We win together, celebrate often, and reward performance. If you want to sell a category-defining product with real ownership, this is your team. What you'll do We're seeking an experienced Senior Manager to lead our Sales Development organization. In this second-line leadership role, you will manage a team of SDR Managers, drive pipeline generation strategy, and build the scalable systems that turn early-career sales talent into high-performing revenue contributors. Where you'll work This role will be based in our San Francisco office. We are a hybrid environment that combines the energy and connections of being in the office with the benefits and flexibility of working from home. We currently require a mini

AIGoExcelMarketing
D
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

$186.6K – $230.5K/yr

Quick readStrong listing-quality and freshness signals

Drata is building the trust layer between great companies - automating compliance, managing risk, and helping organizations prove trust continuously as they scale. We're Dratanauts: a global crew of 600+ professionals united by a culture that rewards integrity, ownership, and raising the bar, no matter where in the world we're working from. Why Join the Drata Team? At Drata, you're not maintaining legacy compliance software - you're building the agentic AI platform defining what trust looks like for the next generation of companies. Here's what makes the work itself worth showing up for: Problems without a playbook: You'll work at the edge of AI and security, building agentic governance, continuous compliance, and real-time trust verification to solve problems that don't have an established answer yet. You're writing it as you go. Real ownership, not just process: Our values center on owning outcomes and raising the bar, not checking boxes. You're expected to have opinions and back them. A seat at the table: Your perspective is unique and valued. Open debate and diverse viewpoints are built into how decisions actually get made here, at every level. Growth at rocketship speed: Drata is scaling fast, which means scope grows fast too. High performers get more ownership, visibility, and experience. A crew, not just coworkers: Dratanauts consistently describe a "come as you are" culture with sharp, curious people—the kind of team that makes hard problems genuinely fun to solve. See what they say here and follow us on LinkedIn for company news, employee stories, and career updates. Job Summary: We are looking for a Senior Business Development Lead, Cloud Service Providers to join the Drata team. This is a senior individual contributor role responsible for leading and expanding Drata's strategic partnerships across major cloud providers, including AWS. As the primary owner of our CSP partner strategy, you will shape how Drata co-sells, co-markets, and integrates within the

AWSAzureGCPRest
N
📍 Santa Clara, United States
✓ High-confidence listingCompany trend -8%
Quick readStrong listing-quality and freshness signals

As one of the technology industry's most desirable employers, NVIDIA has been redefining accelerated computing, computer graphics and leading the Artificial Intelligence revolution. NVIDIA's innovation is fueled by its great technology—and amazing people. We are seeking a Senior Silicon and System Product Lead to influence, innovate and take our next generation products to the market. As part of the Silicon Solutions Team, we architect and deliver groundbreaking system solutions that integrate all aspects of the system from silicon design, software design to operations and final deployment in multiple market segments that NVIDIA serves. This position offers an unique opportunity to collaborate with multiple organizations in the company and grow your career in a high impact role. We need a passionate, hard-working and creative individual to lead the products all the way from market analysis to delivering the features on the final product. What you'll be doing: Drive product performance and power targets, trade-off features/configurations and provide innovative solutions to complex silicon and system level problems. Evaluate new market segments and use cases; translate market requirements to engineering problem statements and metrics. Innovate Performance, power, yield and quality optimizations and features for the world’s fastest power-shipping products in the GPU and SoC market segments spanning gaming, automotive, datacenter and DL/AI. Develop methodologies and requirements for multi-functional teams to drive silicon and system product features to production. Incorporate productization feedback to improve the next generation. Lead the team for feature requirements and schedule from architecture to silicon phase of projects. Work alongside system architects, designers, marketing teams, chip and board designers, software/firmware engineers, HW/S

Artificial IntelligenceAI
N
📍 Santa Clara, United States
✓ High-confidence listingCompany trend -8%
Quick readStrong listing-quality and freshness signals

NVIDIA has been transforming computer graphics, PC gaming, and accelerated computing for more than 25 years. It’s a unique legacy of innovation that’s fueled by great technology—and amazing people. Today, we’re tapping into the unlimited potential of AI to define the next era of computing. An era in which our GPU acts as the brain of computers, robots, and self-driving cars that can understand the world. Doing what’s never been done before takes vision, innovation, and the world’s best talent. As a NVIDIAN, you’ll be immersed in a diverse, supportive environment where everyone is inspired to do their best work. Come join the team and see how you can make a lasting impact on the world. NVIDIA Silicon Codesign Group is seeking a versatile engineer to join the HW bring-up methodology team. The SCG team is uniquely positioned to have an end-to-end view of the product development cycle - from early architecture definition, through bringup, to product release. What will you be doing: Led end-to-end planning and on-time execution of Nvidia's new chip bringup effort, from pre-silicon through production deployment. Coordinate multi-functional teams across Architecture, Build, Validation, DFT, SW, System, and Operations to drive shared bringup achievements. Improve cross-team communication, work, and handoffs. Develop and standardize methodologies, processes, and workflows for silicon bringup, creating reusable checklists and playbooks. Drive scheduling, equipment, and material logistics to support ambitious NPI and production schedules. Lead post-action reviews and convert learnings into concrete process improvements for future silicon and solution bringups. Contribute to post-silicon learnings that feed back into architecture, design, and pre-silicon

AILogistics
P
📍 Connecticut, United States
✓ High-confidence listingCompany trend +671.4%

$88.5K – $147.5K/yr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY The Asset Lifecycle Management (ALM) Lead is responsible for the systematic tracking, installation, and removal of laboratory equipment throughout the entire lifecycle, from acquisition through deployment, maintenance, and final disposal. Operating within an R&D environment, this role facilitates asset preplanning, site assessments, and ensures all asset-related activities are documented, tracked, and compliant with regulatory standards. By optimizing equipment usage, managing inventory, coordinating maintenance, and driving process improvements, the ALM supports efficient and safe laboratory operations while controlling costs and enabling the lab for evolving technological requirements. This is to include but not be limited to supporting the regular updates and reconciliation of the Fixed Asset Registry (FAR) and physical inventory field activities. With input from both the customer equipment owner and the original equipment manufacturer (OEM), this role will develop the correct service program for assets within EAMS (Enterprise Asset Management System) or Pfizer’s Computerized Maintenance Management System (CMMS). Additionally, this position will be responsible for the documentation of asset maintenance activities within EAMS and support site EAMS administration requiring the review of training requirements and On the Job Training (OJT) for new resources requiring system access. The Asset Lifecycle Manager will also represent the site on various Global Workplace Experience (GWE) Communities of Practice or multi-site or global teams ensuring best practices and standards are being leveraged across the broader R&D portfolio. This position will foster and maintain working relationships with GWE, Preclinical & Translational Sciences (P&TS) Research and business operations team colleague and contractors to analyze needs, provide recommendations, and execute plans and options that ali

AIExcelProject ManagementAccounting
C
📍 Tampa Florida United States, United States
✓ High-confidence listingCompany trend +800%
Quick readStrong listing-quality and freshness signals

This is a senior attorney role to lead the negotiation and execution of derivatives documentation supporting our global Markets trading activities. This role will serve as a key partner to front office, risk, and legal teams, managing complex master trading agreements, such as ISDA and Futures Clearing agreements, and advising on legal and regulatory risk across OTC derivatives transactions. The position requires deep expertise in ISDA Master Agreements, collateral documentation, and derivatives market practice, along with strong stakeholder management and negotiation capabilities. Responsibilities: Serve as lead negotiator and subject matter expert for ISDA Master Agreements, Schedules, Credit Support Annexes (CSAs), and related derivatives and collateral documentation; manage complex, bespoke negotiations across the full documentation lifecycle Provide legal counsel and guidance to Markets business stakeholders, interpreting applicable laws, rules, regulations, and industry practices and delivering commercially practical, risk-appropriate solutions Advise senior management on legal matters impacting trading activities, client relationships, and strategic initiatives, contributing informed, business-oriented perspectives to decision-making Identify, evaluate, and manage legal, regulatory, and reputational risk in coordination with Legal, Risk, and ICRM; ensure alignment with internal policies and applicable regulatory requirements Objectively assess business proposals against institutional risk appetite, regulatory frameworks, and market standards, escalating issues as appropriate Collaborate closely with Trading, Sales, Credit, Risk, Operations, and Legal teams across regions to deliver coordinated, efficient, and consistent outcomes Oversee day-to-day legal and documentation activities as a subject matter expert, ensuring tim

Artificial IntelligenceAI
C
📍 Farmington, United States
✓ High-confidence listingCompany trend +340.2%
Quick readStrong listing-quality and freshness signals

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Position Summary At Aetna®, part of CVS Health, we proudly serve more than 26 million medical members through our broad range of health plan offerings. We're committed to delivering a simpler, more meaningful, and personal health care experience to each of them. As a Senior Manager Medicare Product, Vendor Management Contract Lead you will play a critical role contracting, negotiations, oversight of vendors and assisting in achieving CVS goals, work strategically together, and remain as adaptable as possible in an ever-changing environment. This role's scope of responsibility includes overseeing the following in relation to Medicare Product vendor management: Finance, Contracts, Invoicing, Negotiations, Provisioning, Aetna Medicare Supplemental & Duals benefits, Vendor relationship management, Compliance oversight, Auditing, and projects as assigned. The Senior Manager, Vendor Management Contract Lead is a high impact role. You will lead advance contract and negotiation skills, work with other partner to identify root cause, address, and resolve vendor issues, manage vendors to the contract SLAs, performance guarantees and provide insight into complex vendor problems. Responsibilities include: Work assignments involving moderately complex to complex issues where the analysis of situations or data requires an in-dep

FinanceAuditing
G
📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$157.6K – $203.9K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description Gilead Sciences is seeking a collaborative, hands-on leader to shape and deliver the ERP capabilities for a new, next-generation bulk drug substance manufacturing facility at our Foster City site. As the site’s SAP business lead, you will translate operational needs into integrated processes across production, procurement, quality, and warehousing. Working closely with site stakeholders and the IT implementation team, you will define requirements, guide implementation, and connect SAP with other digital platforms to help create a compliant, paperless manufacturing environment. R

SapLogisticsProcurementWarehouse
G
📍 California, United States
✓ Quality checkedCompany trend +190.5%

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Real-World Evidence (RWE) function at Gilead is part of the Clinical Data Sciences (CDS) group within the Clinical Development organization and aims to unlock the power of Real-World Data (RWD) to help transform innovations to life-changing medicines for patients. We are seeking a Senior Director, RWE Inflammation Product Lead who will be accountable for the development and execution of the RWE strategy in support of one or more Inflammation products under development. The incumbent will serve as the key RWE subject matter expert within Gilead's lifecycle management teams for the product(s) and all its indications across the development lifecycle and serve as a strategic

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